Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 1996
  2. Published

    Positive effects on plasma glucose & appetite by industrial modification of starch

    Raben, A., Andersen, K., Karberg, M. A., Holst, Jens Juul & Astrup, A., 1996. 1 p.

    Research output: Contribution to conference › Poster › Research

  3. Published

    Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients

    Willms, B., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Nauck, M. A., Jan 1996, In: Endocrinology. 81, 1, p. 327-32 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Impaired insulin-stimulated nonoxidative glucose metabolism in glucose-tolerant women with previous gestational diabetes

    Damm, Peter, drb459, drb459, Kühl, C. E. & Pedersen, Oluf Borbye, Feb 1996, In: American Journal of Obstetrics and Gynecology. 174, 2, p. 722-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Studies of insulin resistance in congenital generalized lipodystrophy

    Søvik, O., drb459, drb459, Trygstad, O. & Pedersen, Oluf Borbye, Jun 1996, In: Acta Paediatrica. Supplement. 413, p. 29-37 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Handedness in twins according to zygosity and chorion type: a preliminary report

    Derom, C., Thiery, E., Vlietinck, R., Loos, Ruth & Derom, R., Jul 1996, In: Behavior Genetics. 26, 4, p. 407-8 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Cloning of the fomA gene, encoding the major outer membrane porin of Fusobacterium nucleatum ATCC10953

    Jensen, H. B., Skeidsvoll, J., Fjellbirkeland, A., Høgh, Birthe, Puntervoll, P., Kleivdal, H. & Tommassen, J., Nov 1996, In: Microbial Pathogenesis. 21, 5, p. 331-42 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 1997
  9. Published

    Posttranslational processing of proglucagon and postsecretory fate of proglucagon products.

    Holst, Jens Juul, Ørskov, C., Hartmann, B. & Deacon, Carolyn F., 1997, The Insulinotropic Gut Hormone Glucagon-like Peptide-1.. Basel: Karger, p. 24-48

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  10. Published

    Identification of a common amino acid polymorphism in the p85alpha regulatory subunit of phosphatidylinositol 3-kinase: effects on glucose disappearance constant, glucose effectiveness, and the insulin sensitivity index

    Hansen, Torben, Andersen, C. B., Echwald, S. M., Urhammer, S. A., Clausen, J. O., drb459, drb459, Owens, D., Hansen, L. & Pedersen, Oluf Borbye, Mar 1997, In: Diabetes. 46, 3, p. 494-501 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Short- and long-term metabolic effects of recombinant human IGF-I treatment in patients with severe insulin resistance and diabetes mellitus

    Vestergaard, H., Rossen, M., Urhammer, S. A., Müller, J. & Pedersen, Oluf Borbye, May 1997, In: European Journal of Endocrinology. 136, 5, p. 475-82 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Population studies of the human V kappa A18 gene polymorphism in Caucasians, blacks and Eskimos. New functional alleles and evidence for evolutionary selection of a more restricted antibody repertoire

    Juul, Lars, Hougs, L., Andersen, V., Garred, Peter, Ryder, L., Svejgaard, A., Høgh, Birthe, Lamm, L., Graugaard, B. & Barington, T., Jun 1997, In: Tissue Antigens. 49, 6, p. 595-604 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Chromosomal mapping and mutational analysis of the coding region of the glycogen synthase kinase-3alpha and beta isoforms in patients with NIDDM

    Hansen, L., Arden, K. C., Rasmussen, S. B., Viars, C. S., drb459, drb459, Hansen, Teis Schjals, Møller, A. M., Woodgett, J. R. & Pedersen, Oluf Borbye, Aug 1997, In: Diabetologia. 40, 8, p. 940-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Expression of protein-tyrosine phosphatases in the major insulin target tissues

    Norris, K., Norris, F., Kono, D. H., drb459, drb459, Pedersen, Oluf Borbye, Theofilopoulos, A. N. & Møller, N. P., 6 Oct 1997, In: FEBS Letters. 415, 3, p. 243-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The Matola malaria project: a temporal and spatial study of malaria transmission and disease in a suburban area of Maputo, Mozambique

    Thompson, R., Begtrup, K., Cuamba, N., Dgedge, M., Mendis, C., Gamage-Mendis, A., Enosse, S. M., Barreto, J., Sinden, R. E. & Høgh, Birthe, Nov 1997, In: American Journal of Tropical Medicine and Hygiene. 57, 5, p. 550-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 1998
  17. Published

    Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.

    Deacon, Carolyn F., Hughes, T. E. & Holst, Jens Juul, 1998, In: Diabetes. 47, p. 764-769

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity

    Deacon, Carolyn F., Knudsen, L. B., Madsen, K., Wiberg, F. C., Jacobsen, O. & Holst, Jens Juul, 1998, In: Diabetologia. 41, p. 271-278

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes

    Holst, Jens Juul & Deacon, Carolyn F., 1998, In: Diabetes. 47, p. 1663-1670

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    On the treatment of diabetes mellitus with glucagon-like peptide-1.

    Holst, Jens Juul, Deacon, Carolyn F., Toft-Nielsen, M. & Bjerre-Knudsen, L., 1998, In: Annals of the New York Academy of Sciences. 865, p. 336-343

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The differing impact of chloroquine and pyrimethamine/sulfadoxine upon the infectivity of malaria species to the mosquito vector

    Høgh, Birthe, Gamage-Mendis, A., Butcher, G. A., Thompson, R., Begtrup, K., Mendis, C., Enosse, S. M., Dgedge, M., Barreto, J., Eling, W. & Sinden, R. E., Feb 1998, In: American Journal of Tropical Medicine and Hygiene. 58, 2, p. 176-82 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Decarboxylation-based traceless linking with Aroyl acrylic acids

    Garibay, P., Nielsen, J. & Hoeg-Jensen, T., 9 Apr 1998, In: Tetrahedron Letters. 39, 15, p. 2207-2210 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Nye farmaka til behandling af malaria

    Høgh, Birthe, 10 Aug 1998, In: Ugeskrift for Laeger. 160, 33, p. 4783-6 4 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Different molecular events result in low protein levels of mannan-binding lectin in populations from southeast Africa and South America

    Madsen, H. O., Satz, M. L., Høgh, Birthe, Svejgaard, A. & Garred, Peter, 15 Sep 1998, In: Journal of immunology (Baltimore, Md. : 1950). 161, 6, p. 3169-75 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1α gene on estimates of the pancreatic β-cell function in Caucasian glucosetolerant first-degree relatives of type 2 diabetic patients

    Urhammer, Søren Asger, Møller, Ann, Nyholm, B., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Clausen, J. O., Hansen, Torben, Pedersen, Oluf Borbye & Schmitz, O., 20 Nov 1998, In: Journal of Clinical Endocrinology and Metabolism. 83, 11, p. 3992-3995 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    The Ala/Va198 polymorphism of the hepatocyte nuclear factor-1α gene contributes to the interindividual variation in serum C-peptide response during an oral glucose tolerance test: Evidence from studies of 231 glucose- tolerant first degree relatives of type 2 diabetic probands

    Urhammer, Søren Asger, Hansen, Torben, Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff & Pedersen, Oluf Borbye, 1 Dec 1998, In: Journal of Clinical Endocrinology and Metabolism. 83, 12, p. 4506-4509 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 1999
  28. Published

    Alternative splicing of exon 17 and a missense mutation in exon 20 of the insulin receptor gene in two brothers with a novel syndrome of insulin resistance (congenital fiber-type disproportion myopathy)

    Vorwerk, P., Christoffersen, C. T., Müller, J., drb459, drb459, Pedersen, Oluf Borbye, De Meyts, P. & drb459, drb459, 1999, In: Hormone Research. 52, 5, p. 211-20 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Bivariant periodic cyclic homology

    Grønbæk, Christian, 1999, USA: Chapman & Hall/CRC. (Research Notes in Mathematics).

    Research output: Book/Report › Book › Research › peer-review

  30. Published

    Intermediate Expansions of a GAA Repeat in the Frataxin Gene are not associated with Type 2 Diabetes or Altered Glucose-Induced ¿-cell function in Danish Caucasians

    Dalgaard, L. T., Hansen, T., Urhammer, S. A., Clausen, J. O., Eiberg, Hans Rudolf Lytchoff & Pedersen, Oluf Borbye, 1999, In: Diabetes. 48, p. 914-917

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Low incidence rate of overt hypothyroidism compared with hyperthyroidism in an area with moderately low iodine intake

    Laurberg, P., Bülow Pedersen, I., Pedersen, K. M. & drb459, drb459, Jan 1999, In: Thyroid. 9, 1, p. 33-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Implications of compound heterozygous insulin receptor mutations in congenital muscle fibre type disproportion myopathy for the receptor kinase activation

    Klein, H. H., Müller, R., drb459, drb459 & Pedersen, Oluf Borbye, Feb 1999, In: Diabetologia. 42, 2, p. 245-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Mutational analysis of the coding regions of the genes encoding protein kinase B-alpha and -beta, phosphoinositide-dependent protein kinase-1, phosphatase targeting to glycogen, protein phosphatase inhibitor-1, and glycogenin: lessons from a search for genetic variability of the insulin-stimulated glycogen synthesis pathway of skeletal muscle in NIDDM patients

    Hansen, L., Fjordvang, H., Rasmussen, S. K., drb459, drb459, Echwald, S. M., Hansen, Teis Schjals, Alessi, D., Shenolikar, S., Saltiel, A. R., Barbetti, F. & Pedersen, Oluf Borbye, Feb 1999, In: Diabetes. 48, 2, p. 403-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Studies of gene expression and activity of hexokinase, phosphofructokinase and glycogen synthase in human skeletal muscle in states of altered insulin-stimulated glucose metabolism

    drb459, drb459, Feb 1999, In: Danish Medical Bulletin (Print). 46, 1, p. 13-34 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Intact proinsulin and beta-cell function in lean and obese subjects with and without type 2 diabetes

    Røder, M. E., Dinesen, B., Hartling, S. G., Houssa, P., drb459, drb459, Sodoyez-Goffaux, F. & Binder, C., Apr 1999, In: Diabetes Care. Supplement. 22, 4, p. 609-14 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Insulin resistance, exercise capacity and body composition in subjects with two hypertensive parents

    Andersen, U. B., Dige-Petersen, H., Ibsen, H., Skøtt, P., Bruun, Niels Eske, drb459, drb459 & Christiansen, C., Sep 1999, In: Journal of Hypertension. 17, 9, p. 1273-80 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: Evaluation of their relation with alterations in insulin secretion and insulin sensitivity

    Almind, K., Frederiksen, S. K., Bernal, D., Hansen, Torben, Ambye, L., Urhammer, Søren Asger, Ekstrøm, Claus Thorn, Berglund, L., Reneland, R., Lithell, H., White, M. F., Van Obberghen, E. & Pedersen, Oluf Borbye, 11 Oct 1999, In: Diabetologia. 42, 10, p. 1244-1249 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Diabetic intestinal growth adaptation and glucagon-like peptide 2 in the rat: effects of dietary fibre

    Thulesen, J., Hartmann, Bolette, Nielsen, C., Holst, Jens Juul & Poulsen, Steen Seier, Nov 1999, In: Gut. 45, 5, p. 672-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2000
  40. Published

    Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice

    Hartmann, Bolette, Thulesen, J., Kissow, Hannelouise, Thulesen, S., Ørskov, Cathrine, Ropke, C., Poulsen, Steen Seier & Holst, Jens Juul, 2000, In: Endocrinology. 141, 11, p. 4013-20 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells

    Schmidt, P. T., Hartmann, Bolette, Bregenholt, S., Holst, Jens Juul & Claesson, Mogens Helweg, 1 May 2000, In: Scandinavian Journal of Gastroenterology. 35, 5, p. 522-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colon

    Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Hansen, B. S., Holst, Jens Juul, Poulsen, Steen Seier & Mortensen, P. B., Sep 2000, In: Gut. 47, 3, p. 370-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Chemokines and chemokine receptors in inflammation of the nervous system: manifold roles and exquisite regulation

    Huang, D., Han, Y., Rani, M. R., Glabinski, A., Trebst, C., Sørensen, Torben Lykke, Tani, M., Wang, J., Chien, P., O'Bryan, S., Bielecki, B., Zhou, Z., Majumder, S. & Ransohoff, R. M., Oct 2000, In: Immunological Reviews. 177, p. 52-67 16 p.

    Research output: Contribution to journal › Journal article › Research

  44. Published

    Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2

    Thulesen, J., Hartmann, Bolette, Ørskov, Cathrine, Jeppesen, Palle Bekker, Holst, Jens Juul & Poulsen, Steen Seier, Oct 2000, In: Peptides. 21, 10, p. 1511-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Interaktion mellem warfarin og oral miconazol-gel

    Ogard, C. G. & drb459, drb459, 9 Oct 2000, In: Ugeskrift for Laeger. 162, 41, p. 5511

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Studies of the variability of the genes encoding the insulin-like growth factor I receptor and its ligand in relation to type 2 diabetes mellitus

    Rasmussen, S. K., Lautier, C., Hansen, L., Echwald, S. M., Hansen, Torben, Ekstrøm, Claus Thorn, Urhammer, Søren Asger, Borch-Johnsen, K., Grigorescu, F., Smith, R. J. & Pedersen, Oluf Borbye, 1 Dec 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, 4, p. 1606-1610 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2001
  48. Published

    A prevalent polymorphism in the putative promotor of the UCP3 gene and its relationship to body mass index in the Danish population

    Dalgaard, L. T., Sørensen, Thorkild I.A., Drivsholm, T. B., Borch-Johnsen, K., Andersen, T., Hansen, T. & Pedersen, Oluf Borbye, 2001, In: Journal of Clinical Endocrinology and Metabolism. 86, p. 1398-1402

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Intestinal growth adaptation and glucagon-like peptide 2 in rats with ileal--jejunal transposition or small bowel resection

    Thulesen, J., Hartmann, Bolette, Kissow, Hannelouise, Jeppesen, Palle Bekker, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2001, In: Digestive Diseases and Sciences. 46, 2, p. 379-88 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    The association between the val/ala-55 polymorphism of the uncoupling protein 2 gene and exercise efficiency

    Buemann, B., Schierning, B., Toubro, S., Bibby, B. M., Sørensen, Thorkild I.A., Dalgaard, L., Pedersen, Oluf Borbye & Astrup, A., 2001, In: International Journal of Obesity. 25, p. 467-471 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus

    Hansen, L., Jensen, J. N., Ekstrøm, Claus Thorn, drb459, drb459, Hansen, Teis Schjals, Pedersen, Oluf Borbye & drb459, drb459, Feb 2001, In: Diabetologia. 44, 2, p. 237-240 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Center for epidemiologisk grundforskning.

    Olsen, J., Melbye, M., Sørensen, Thorkild I.A. & Aaby, P., 26 Feb 2001, In: Ugeskrift for Laeger. 163, 9, p. 1296-1297 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon

    Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Graff, J., Lohmann, J., Hansen, B. S., Tofteng, F., Poulsen, Steen Seier, Madsen, J. L., Holst, Jens Juul & Mortensen, P. B., Mar 2001, In: Gastroenterology. 120, 4, p. 806-815 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Serum leptin levels in pregnant women with type 1 diabetes mellitus

    Lauszus, F., Schmitz, O., drb459, drb459, Klebe, J. G., Pedersen, Oluf Borbye & drb459, drb459, Jul 2001, In: Acta Obstetricia et Gynecologica Scandinavica. 80, 7, p. 596-601 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Increments in insulin sensitivity during intensive treatment are closely correlated with decrements in glucocorticoid receptor mRNA in skeletal muscle from patients with Type II diabetes

    drb459, drb459, Bratholm, P. & Christensen, Niels Johan, Nov 2001, In: Clinical Science. 101, 5, p. 533-40 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Rosiglitazone treatment of patients with extreme insulin resistance and diabetes mellitus due to insulin receptor mutations has no effects on glucose and lipid metabolism

    drb459, drb459, Lund, S., Pedersen, Oluf Borbye & drb459, drb459, Nov 2001, In: Journal of Internal Medicine. 250, 5, p. 406-14 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. 2002
  58. Published

    Fat mass measured by DXA varies with scan velocity

    Black, E., Petersen, L., Kreutzer, M., Toubro, S., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Astrup, A., 2002, In: Obesity. 10, 2, p. 69-77 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function

    Hansen, S. K., Párrizas, M., Jensen, M. L., Pruhova, S., Ek, J., Boj, S. F., Johansen, A., Maestro, M. A., Rivera, F., Eiberg, Hans Rudolf Lytchoff, Andel, M., Lebl, J., Pedersen, Oluf Borbye, Ferrer, J. & Hansen, Torben, 2002, In: Journal of Clinical Investigation. 110, 6, p. 827-33 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Jagten på de genetiske determinanter for de formodede polygene former for type 2-diabetes. Status og perspektivering

    Pedersen, Oluf Borbye, Hansen, Torben, Hansen, L., Echwald, S. M. & Urhammer, S. A., 2002, In: Ugeskrift for Laeger. 164, 16, p. 2163-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Long-term AICAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome

    Buhl, E. S., Jessen, N., Pold, R., Ledet, T., Flyvbjerg, A., Pedersen, Steen, Pedersen, Oluf Borbye, Schmitz, O. & Lund, S., 2002, In: Diabetes. 51, 7, p. 2199-206 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Maturity-onset diabetes of the young--MODY. Molekylaergenetiske, patofysiologiske og kliniske karakteristika

    Hansen, Torben, Urhammer, S. A. & Pedersen, Oluf Borbye, 2002, In: Ugeskrift for Laeger. 164, 15, p. 2017-22 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    PC-1 amino acid variant (K121Q) has no impact on progression of diabetic nephropathy in type 1 diabetic patients

    Jacobsen, P., Grarup, Niels, Tarnow, L., Parving, H. & Pedersen, Oluf Borbye, 2002, In: Nephrology, Dialysis, Transplantation. 17, 8, p. 1408-12 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians

    Rasmussen, S. K., Urhammer, S. A., Berglund, L. E., Jensen, J. N., Hansen, L., Echwald, S. M., Borch-Johnsen, K., Horikawa, Y., Mashima, H., Lithell, H., Cox, N. J., Hansen, Torben, Bell, G. I. & Pedersen, Oluf Borbye, 2002, In: Diabetes. 51, 12, p. 3561-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

    Almind, K., Delahaye, L., Hansen, Torben, Van Obberghen, E., Pedersen, Oluf Borbye & Kahn, C. R., 19 Feb 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 4, p. 2124-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon

    Haderslev, Kent Valentin, Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Sorensen, H. A., Graff, J., Tofteng, F., Poulsen, S. S., Madsen, J. L., Holst, Jens Juul, Staun, Michael, Mortensen, P. B. & Poulsen, Steen Seier, 1 Apr 2002, In: Scandinavian Journal of Gastroenterology. 37, 4, p. 392-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Normocalcemia and persistent elevated serum concentrations of 1-84 parathyroid hormone after operation for sporadic parathyroid adenoma: evidence of increased morbidity from cardiovascular disease

    drb459, drb459 & ØStergaard Kristensen, L., Jun 2002, In: World Journal of Surgery. 26, 6, p. 657-60 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. 2003
  69. Published

    A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians

    Muller, Y. L., Bogardus, C., Pedersen, Oluf Borbye & Baier, L., 2003, In: Diabetes. 52, 3, p. 895-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity

    Frayling, T. M., Lindgren, C. M., Chevre, J. C., Menzel, S., Wishart, M., Benmezroua, Y., Brown, A., Evans, J. C., Rao, P. S., Dina, C., Lecoeur, C., Kanninen, T., Almgren, P., Bulman, M. P., Wang, Y., Mills, J., Wright-Pascoe, R., Mahtani, M. M., Prisco, F., Costa, A. & 9 others, Cognet, I., Hansen, Torben, Pedersen, Oluf Borbye, Ellard, S., Tuomi, T., Groop, L. C., Froguel, P., Hattersley, A. T. & Vaxillaire, M., 2003, In: Diabetes. 52, 3, p. 872-81 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Evidence for an association between the Leu162Val polymorphism of the PPARalpha gene and decreased fasting serum triglyceride levels in glucose tolerant subjects

    Nielsen, E. D., Hansen, L., Echwald, S. M., Drivsholm, Thomas, Borch-Johnsen, K., Ekstrøm, C. T., Hansen, Torben & Pedersen, Oluf Borbye, 2003, In: Pharmacogenetics and Genomics. 13, 7, p. 417-23 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Impact of low-dose acetylsalicylic acid on kidney function in type 2 diabetic patients with elevated urinary albumin excretion rate

    Gaede, P., Hansen, H. P., Parving, H. & Pedersen, Oluf Borbye, 2003, In: Nephrology, Dialysis, Transplantation. 18, 3, p. 539-42 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Impact of two common polymorphisms in the PPARgamma gene on glucose tolerance and plasma insulin profiles in monozygotic and dizygotic twins: thrifty genotype, thrifty phenotype, or both?

    Poulsen, P., Andersen, G., Fenger, M., Hansen, Torben, Echwald, S. M., Vølund, A., Beck-Nielsen, H., Pedersen, Oluf Borbye & Vaag, Allan, 2003, In: Diabetes. 52, 1, p. 194-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Injected TFF1 and TFF3 bind to TFF2-immunoreactive cells in the gastrointestinal tract in rats

    Poulsen, Steen Seier, Thulesen, J., Hartmann, Bolette, Kissow, Hannelouise, Nexø, E. & Thim, L., 2003, In: Regulatory Peptides. 115, 2, p. 91-99 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Insulin resistance and maximal oxygen uptake

    Seibaek, M., drb459, drb459, Burchardt, H., Sloth, C., Torp-Pedersen, Christian, Nielsen, S. L., Hildebrandt, P. & Pedersen, Oluf Borbye, 2003, In: Clinical Cardiology. 26, 11, p. 515-20 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Intensified multifactorial intervention and cardiovascular outcome in type 2 diabetes: the Steno-2 study

    Pedersen, Oluf Borbye & Gaede, P., 2003, In: Metabolism. 52, 8 Suppl 1, p. 19-23 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes

    Gaede, P., Vedel, P., Larsen, N., Jensen, G. V. H., Parving, H. & Pedersen, Oluf Borbye, 2003, In: Briefings from the New England Journal of Medicine. 348, 5, p. 383-93 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Steno-2-studiet: intensiv multifaktoriel behandling reducerer forekomsten af kardiovaskulaer sygdom hos patienter med type 2-diabetes

    Gaede, P. H., Jepsen, P. V., Larsen, J. N. B., Jensen, G. V., Parving, H. & Pedersen, Oluf Borbye, 2003, In: Ugeskrift for Laeger. 165, 26, p. 2658-61 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes

    Nielsen, E. D., Hansen, L., Carstensen, Bendix, Echwald, S. M., Drivsholm, Thomas, Glümer, C., Thorsteinsson, B., Borch-Johnsen, K., Hansen, Torben & Pedersen, Oluf Borbye, 2003, In: Diabetes. 52, 2, p. 573-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    The 5-HT1A serotonin receptor is located on calbindin- and parvalbumin-containing neurons in the rat brain

    Aznar, S., Qian, Z., Shah, R., Kornum, Birgitte Rahbek & Knudsen, Gitte Moos, 3 Jan 2003, In: Brain Research. 959, 1, p. 58-67 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Activity-induced and developmental downregulation of the Nogo receptor

    Josephson, A., Trifunovski, A., Schéele, Camilla Charlotte Nielsen, Widenfalk, J., Wahlestedt, C., Brené, S., Olson, L. & Spenger, C., Mar 2003, In: Cell and Tissue Research. 311, 3, p. 333-42 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects

    Sørensen, L. B., Flint, A., Raben, Anne, Hartmann, Bolette, Holst, Jens Juul & Astrup, A., Apr 2003, In: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 27, 4, p. 450-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Association of a functional 17beta-estradiol sensitive IL6-174G/C promoter polymorphism with early-onset type 1 diabetes in females

    Kristiansen, O. P., Nolsøe, R. L., Larsen, L., Gjesing, A. M. P., Johannesen, J., Larsen, Z. M. E., Lykkesfeldt, A. E., Karlsen, A. E., Pociot, Flemming, Mandrup-Poulsen, Thomas & DIEGG, D., 15 May 2003, In: Human Molecular Genetics. 12, 10, p. 1101-10 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development

    Petersen, Y. M., Hartmann, Bolette, Holst, Jens Juul, Le Huerou-Luron, I., Bjørnvad, Charlotte Reinhard & Sangild, Per Torp, Jun 2003, In: Journal of Nutrition. 133, 6, p. 1781-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    GLP-2-mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TPN-fed piglets 1

    Guan, X., Stoll, B., Lu, X., Tappenden, K. A., Holst, Jens Juul, Hartmann, Bolette & Burrin, D. G., Jul 2003, In: Gastroenterology. 125, 1, p. 136-47 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes

    Gual, P., Gonzalez, T., Grémeaux, T., Barrès, Romain, Le Marchand-Brustel, Y. & Tanti, J., 18 Jul 2003, In: Journal of Biological Chemistry. 278, 29, p. 26550-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety

    Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Hartmann, Bolette, Holst, Jens Juul & Hellström, P. M., 15 Nov 2003, In: Regulatory Peptides. 116, 1-3, p. 21-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Fatty acid-induced insulin resistance: role of insulin receptor substrate 1 serine phosphorylation in the retroregulation of insulin signalling

    Le Marchand-Brustel, Y., Gual, P., Grémeaux, T., Gonzalez, T., Barrès, Romain & Tanti, J., Dec 2003, In: Biochemical Society Transactions. 31, Pt 6, p. 1152-6 5 p.

    Research output: Contribution to journal › Journal article › Communication

  89. 2004
  90. Published

    A common polymorphism in the promoter of the IGF-I gene associates with increased fasting serum triglyceride levels in glucose-tolerant subjects

    Nielsen, E. D., Hansen, L., Lajer, M., Andersen, K. L., Echwald, S. M., Urhammer, S. A., Hansen, Torben & Pedersen, Oluf Borbye, 2004, In: Clinical Biochemistry. 37, 8, p. 660-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene

    Højlund, K., Hansen, Torben, Lajer, M., Henriksen, J. E., Levin, K., Lindholm, J., Pedersen, Oluf Borbye & Beck-Nielsen, H., 2004, In: Diabetes. 53, 6, p. 1592-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    A pseudo-sequence method for comparing 7TM receptors with respect to the physicochemical properties of their binding sites

    Frimurer, Thomas Michael, Ulven, Trond, Högberg, T. & Elling, C. E., 2004, Patent No. WO 2004/079625

    Research output: Patent

  93. Published

    Cyclic Quinoline compounds for use in MCH receptor related disorders

    Frimurer, Thomas Michael, Ulven, Trond, Högberg, T., Nørregaard, P. K., Little, P. B. & Receveur, J., 2004, Patent No. WO 2004/052371

    Research output: Patent

  94. Published

    EMPRR: A high-dimensional EM-based piecewise regression algorithm

    Arumugam, Mani & Scott, S. D., 2004, Proceedings of the 2004 International Conference on Machine Learning and Applications, ICMLA '04. Kantardzic, M., Nasraoui, O. & Milanova, M. (eds.). p. 264-271 8 p. (Proceedings of the 2004 International Conference on Machine Learning and Applications, ICMLA '04).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  95. Published

    Expression profiling of insulin action in human myotubes: induction of inflammatory and pro-angiogenic pathways in relationship with glycogen synthesis and type 2 diabetes

    Hansen, L., Gaster, M., Oakeley, E. J., Brusgaard, K., Damsgaard Nielsen, E., Beck-Nielsen, H., Pedersen, Oluf Borbye & Hemmings, B. A., 2004, In: Biochemical and Biophysical Research Communications. 323, 2, p. 685-95 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Facilitated processing of visual stimuli associated with the body

    Whiteley, Louise, Kennett, S., Taylor-Clarke, M. & Haggard, P., 2004, In: Perception. 33, 3, p. 307-14 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Genome sequence of the Brown Norway rat yields insights into mammalian evolution

    Gibbs, R. A., Weinstock, G. M., Metzker, M. L., Muzny, D. M., Sodergren, E. J., Scherer, S., Scott, G., Steffen, D., Worley, K. C., Burch, P. E., Okwuonu, G., Hines, S., Lewis, L., DeRamo, C., Delgado, O., Dugan-Rocha, S., Miner, G., Morgan, M., Hawes, A., Gill, R. & 31 others, Celera, Holt, R. A., Adams, M. D., Amanatides, P. G., Baden-Tillson, H., Barnstead, M., Chin, S., Evans, C. A., Ferriera, S., Fosler, C., Glodek, A., Gu, Z., Jennings, D., Kraft, C. L., Nguyen, T., Pfannkoch, C. M., Sitter, C., Sutton, G. G., Venter, J. C., Woodage, T., Smith, D., Lee, H., Gustafson, E., Cahill, P., Kana, A., Doucette-Stamm, L., Weinstock, K., Fechtel, K., Weiss, R. B., Arumugam, Mani & Rat Genome Sequencing Project Consortium, R. G. S. P. C., 2004, In: Nature. 428, 6982, p. 493-521 29 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Grey-box modelling of pharmacokinetic/pharmacodynamic systems

    Tornøe, C. W., Jacobsen, Judith Lone, Pedersen, Oluf Borbye, Hansen, Torben & Madsen, H. T., 2004, In: Journal of Pharmacokinetics and Pharmacodynamics. 31, 5, p. 401-17 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Handlingsplan om diabetes

    Pedersen, Oluf Borbye, 2004, In: Ugeskrift for Laeger. 166, 12, p. 1099

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Identification of rat genes by TWINSCAN gene prediction, RT-PCR, and direct sequencing

    Wu, J. Q., Shteynberg, D., Arumugam, Mani, Gibbs, R. A. & Brent, M. R., 2004, In: Genome Research. 14, 4, p. 665-71 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Increasing incidence of diabetes after gestational diabetes: a long-term follow-up in a Danish population

    Lauenborg, J., Hansen, Torben, Jensen, D. M., drb459, drb459, Mølsted-Pedersen, L., Hornnes, P., Locht, H., Pedersen, Oluf Borbye & Damm, Peter, 2004, In: Diabetes Care. 27, 5, p. 1194-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Intensive integrated therapy of type 2 diabetes: implications for long-term prognosis

    Gaede, P. & Pedersen, Oluf Borbye, 2004, In: Diabetes. 53 Suppl 3, p. S39-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    Maturity-onset diabetes of the young with end-stage nephropathy: a new indication for simultaneous pancreas and kidney transplantation?

    Saudek, F., Pruhová, S., Boucek, P., Lebl, J., Adamec, M., Ek, J., Pedersen, Oluf Borbye & Hansen, Torben, 2004, In: Transplantation. 77, 8, p. 1298-301 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. Published

    Mutation analysis of NR0B2 among 1545 Danish men identifies a novel c.278G>A (p.G93D) variant with reduced functional activity

    Echwald, S. M., Andersen, K. L., Sørensen, Thorkild I.A., Larsen, L. H., Andersen, T., Tonooka, N., Tomura, H., Takeda, J. & Pedersen, Oluf Borbye, 2004, In: Human Mutation. 24, 5, p. 381-387 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  105. Published

    Quinoline compounds for use in MCH receptor related disorders

    Frimurer, Thomas Michael, Ulven, Trond, Högberg, T., Nørregaard, P. K., Little, P. B. & Receveur, J., 2004, Patent No. WO 2004/052370

    Research output: Patent

  106. Published

    Remission to normoalbuminuria during multifactorial treatment preserves kidney function in patients with type 2 diabetes and microalbuminuria

    Gaede, P., Tarnow, L., Vedel, P., Parving, H. & Pedersen, Oluf Borbye, 2004, In: Nephrology, Dialysis, Transplantation. 19, 11, p. 2784-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  107. Published

    Target intervention against multiple-risk markers to reduce cardiovascular disease in patients with type 2 diabetes

    Gaede, P. & Pedersen, Oluf Borbye, 2004, In: Annals of Medicine. 36, 5, p. 355-66 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  108. Published

    Variation in the interleukin-6 receptor gene associates with type 2 diabetes in Danish whites

    Hamid, Y. H., Urhammer, S. A., Jensen, D. P., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2004, In: Diabetes. 53, 12, p. 3342-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  109. Published

    Increased mortality in patients hospitalized with primary hyperparathyroidism during the period 1977-1993 in Denmark

    Øgard, C. G., Engholm, G., Almdal, Thomas Peter & drb459, drb459, Jan 2004, In: World Journal of Surgery. 28, 1, p. 108-11 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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