Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2004
  2. Published

    Using importance sampling to improve simulation in linkage analysis

    Ängquist, Lars & Hössjer, O., 1 Jan 2004, In: Statistical Applications in Genetics and Molecular Biology. 3, 1, 5.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Alteration in insulin action: role of IRS-1 serine phosphorylation in the retroregulation of insulin signalling

    Tanti, J. F., Gual, P., Grémeaux, T., Gonzalez, T., Barrès, Romain & Le Marchand-Brustel, Y., Feb 2004, In: Annales d'Endocrinologie. 65, 1, p. 43-8 6 p.

    Research output: Contribution to journal › Journal article › Communication

  4. Published

    Keeping hens in tents - Experiences from the first year

    Forkman, Björn, Andersen, Daniel Bjørklund, Hindrup, B. & Horsted, K., Apr 2004, In: British Poultry Science. 45, SUPPL. 1, p. S37-S38

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Glucagon-like peptide-1 secretion is influenced by perfusate glucose concentration and by a feedback mechanism involving somatostatin in isolated perfused porcine ileum

    Hansen, L., Hartmann, Bolette, Mineo, H. & Holst, Jens Juul, 15 Apr 2004, In: Regulatory Peptides. 118, 1-2, p. 11-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Onset of small intestinal atrophy is associated with reduced intestinal blood flow in TPN-fed neonatal piglets

    Niinikoski, H., Stoll, B., Guan, X., Kansagra, K., Lambert, B. D., Stephens, J., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Jun 2004, In: Journal of Nutrition. 134, 6, p. 1467-74 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Transcriptional profiling of extracellular amino acid sensing in Saccharomyces cerevisiae and the role of Stp 1 p and Stp2p

    Eckert-Boulet, N., Nielsen, P. S., Friis, Carsten, Moreira dos Santos, M., Nielsen, J., Kielland-Brandt, M. C. & Regenberg, Birgitte, 1 Jun 2004, In: Yeast. 21, 8, p. 635-648 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Characterization of RNA interference in rat PC12 cells: requirement of GERp95

    Thonberg, H., Schéele, Camilla Charlotte Nielsen, Dahlgren, C. & Wahlestedt, C., 11 Jun 2004, In: Molecular Cell Biology Research Communications. 318, 4, p. 927-34 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The independent effect of type 2 diabetes mellitus on ischemic heart disease, stroke, and death: a population-based study of 13,000 men and women with 20 years of follow-up

    Almdal, Thomas Peter, Scharling, H., Jensen, J. S. & drb459, drb459, 12 Jul 2004, In: J A M A Internal Medicine. 164, 13, p. 1422-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice

    Thulesen, J., Hartmann, Bolette, Hare, K. J., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Aug 2004, In: Gut. 53, 8, p. 1145-1150 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation: effects of different diet regimens

    Paris, M. C., Fuller, P. J., Carstensen, Bendix, Nagy, E., Taylor, R. G., Sourial, M., Holst, Jens Juul, Hartmann, Bolette & Binesm, J. E., Oct 2004, In: Digestive Diseases and Sciences. 49, 10, p. 1688-95 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Studies of the Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene and the relationship to beta-cell function during an OGTT in glucose-tolerant women with and without previous gestational diabetes mellitus

    Lauenborg, J., Damm, Peter, Ek, J., Glümer, C., Jørgensen, Tina, Borch-Johnsen, K., Vestergaard, H., Hornnes, P., Pedersen, Oluf Borbye & Hansen, Torben, Dec 2004, In: Diabetic Medicine. 21, 12, p. 1310-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The potential role of SOCS-3 in the interleukin-1beta-induced desensitization of insulin signaling in pancreatic beta-cells

    Emanuelli, Brice, Glondu, M., Filloux, C., Peraldi, P. & Van Obberghen, E., Dec 2004, In: Diabetes. 53 Suppl 3, p. S97-S103

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2005
  15. Published

    6-Acylamino-2-aminoquinolines as Potent Melanin-Concentrating Hormone 1 Receptor Antagonists

    Ulven, Trond, Frimurer, Thomas Michael, Receveur, J., Little, P. B., Rist, Ø., Nørregaard, P. K. & Högberg, T., 2005, In: Journal of Medicinal Chemistry. 48, 18, p. 5684-5697 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites

    Rose, C. S., Ek, J., Urhammer, S. A., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2005, In: Diabetes. 54, 10, p. 3026-31 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A physicogenetic method to assign ligand-binding relationships between 7TM receptors

    Frimurer, Thomas Michael, Ulven, Trond, Elling, T. C. E., Gerlach, L. O., Kostenis, E. & Högberg, T., 2005, In: Bioorganic & Medicinal Chemistry Letters. 15, 16, p. 3707-3712 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    A prevalent amino acid polymorphism at codon 98 (Ala98Val) of the hepatocyte nuclear factor-1alpha is associated with maturity-onset diabetes of the young and younger age at onset of type 2 diabetes in Asian Indians

    Anuradha, S., Radha, V., Deepa, R., Hansen, Torben, Carstensen, Bendix, Pedersen, Oluf Borbye & Mohan, V., 2005, In: Diabetes Care. 28, 10, p. 2430-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    CRTH2 receptor ligands for therapeutic use

    Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E., Högberg, T., Receveur, J. & Grimstrup, M., 2005, Patent No. WO 2005/115382 A1

    Research output: Patent

  20. Published

    CRTH2 receptor ligands for therapeutic use - B-series

    Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E. & Högberg, T., 2005, Patent No. WO 2005/115374 A1

    Research output: Patent

  21. Published

    Closing in on the C. elegans ORFeome by cloning TWINSCAN predictions

    Wei, C., Lamesch, P., Arumugam, Mani, Rosenberg, J., Hu, P., Vidal, M. & Brent, M. R., 2005, In: Genome Research. 15, 4, p. 577-82 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes

    Torekov, Signe Sørensen, Larsen, L. H., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Holst, Jens Juul, Madsen, O. D., Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Diabetes. 54, 7, p. 2261-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene

    hart, L. M., Hansen, Torben, Rietveld, I., Dekker, J. M., Nijpels, G., Janssen, G. M. C., Arp, P. A., Uitterlinden, A. G., Jørgensen, T., Borch-Johnsen, K., Pols, H. A. P., Pedersen, Oluf Borbye, van Duijn, C. M., Heine, R. J. & Maassen, J. A., 2005, In: Diabetes. 54, 6, p. 1892-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Genetics of type 2 diabetes mellitus: status and perspectives

    Hansen, L. & Pedersen, Oluf Borbye, 2005, In: Diabetes, Obesity and Metabolism. 7, 2, p. 122-35 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Increased risk of intestinal cancer in Crohn's disease: A meta-analysis of population-based cohort studies

    Jess, T., Gamborg, M., Matzen, P., Munkholm, P. & Sørensen, Thorkild I.A., 2005, In: American Journal of Gastroenterology. 100, p. 1-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Mutation analysis of the MCHR1 gene in human obesity

    Wermter, A-K., Reichwald, K., Büch, T., Geller, F., Platzer, C., Huse, K., Hess, C., Remschmidt, H., Gudermann, T., Preibisch, G., Siegfried, W., Goldschmidt, H-P., Li, W-D., Price, R. A., Biebermann, H., Krude, H., Vollmert, C., Wichmann, H-E., Illig, T., Sørensen, T. I. A. & 11 others, Astrup, A., Larsen, L. H., Pedersen, Oluf Borbye, Eberlé, D., Clément, K., Blundell, J., Wabitsch, M., Schäfer, H., Platzer, M., Hinney, A. & Hebebrand, J., 2005, In: European Journal of Endocrinology. 152, 6, p. 851-62 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Mutation analysis of the preproghrelin gene: no association with obesity and type 2 diabetes

    Larsen, L. H., Gjesing, A. P., Sørensen, Thorkild I.A., Hamid, Y. H., Echwald, S. M., Toubro, S., Black, E., Astrup, A., Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Clinical Biochemistry. 38, 5, p. 420-424 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Preparation of phenyl benzoyl pyrazoles as CRTH2 receptor ligands

    Ulven, Trond, Frimurer, Thomas Michael, Rist, O., Kostenis, E., Hoegberg, T., Receveur, J. & Grimstrup, M., 2005, Patent No. WO 2005/115382 A1

    Research output: Patent

  29. Published

    Preparation of substituted thiazoleacetic acids as CRTH2 receptor ligands

    Ulven, Trond, Frimurer, Thomas Michael, Rist, O., Kostenis, E., Hoegberg, T., Receveur, J. & Grimstrup, M., 2005, Patent No. WO 2005/116001 A1

    Research output: Patent

  30. Published

    Prevalence of mutations and functional analyses of melanocortin 4 receptor variants identified among 750 men with juvenile-onset obesity

    Larsen, L. H., Echwald, S. M., Sørensen, Thorkild I.A., Andersen, T., Wulff, B. S. & Pedersen, Oluf Borbye, 2005, In: The Journal of Clinical Endocrinology & Metabolism. 90, 1, p. 219-224 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Quinazoline compounds and their use in MCH-related disease

    Frimurer, Thomas Michael, Ulven, Trond, Högberg, T., Nørregaard, P. K., Little, P. B., Receveur, J. & Grimstrup, M., 2005, Patent No. WO 2005/123714

    Research output: Patent

  32. Published

    Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function

    Neve, B., Fernandez-Zapico, M. E., Ashkenazi-Katalan, V., Dina, C., Hamid, Y. H., Joly, E., Vaillant, E., Benmezroua, Y., Durand, E., Bakaher, N., Delannoy, V., Vaxillaire, M., Cook, T., Dallinga-Thie, G. M., Jansen, H., Charles, M-A., Clément, K., Galan, P., Hercberg, S., Helbecque, N. & 7 others, Charpentier, G., Prentki, M., Hansen, Torben, Pedersen, Oluf Borbye, Urrutia, R., Melloul, D. & Froguel, P., 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 13, p. 4807-12 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release

    Hamid, Y. H., Vissing, H., Holst, Birgitte, Urhammer, S. A., Pyke, C., Hansen, S. K., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Schwartz, Thue W., Pedersen, O. & Hansen, Torben, 2005, In: Diabetic Medicine. 22, 1, p. 74-80 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Studies of variations of the cyclin-dependent kinase inhibitor 1C and the cyclin-dependent kinase 4 genes in relation to type 2 diabetes mellitus and related quantitative traits

    Nielsen, E. D., Hansen, L., Stissing, T., Yanagisawa, K., Borch-Johnsen, K., Poulsen, P., Vaag, Allan, Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Journal of Molecular Medicine. 83, 5, p. 353-61 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Substituted thiazoleacetic acids as CRTH2 receptor ligands

    Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E., Högberg, T., Receveur, J. & Grimstrup, M., 2005, Patent No. WO 2005/116001 A1

    Research output: Patent

  36. Published

    The N363S polymorphism of the glucocorticoid receptor and metabolic syndrome factors in men

    Buemann, B., Black, E., Holst, C., Toubro, S., Echwald, S., Pedersen, Oluf Borbye, Astrup, A. & Sørensen, Thorkild I.A., 2005, In: Obesity Research. 13, 5, p. 862-867 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes

    Ek, J., Rose, C. S., Jensen, D. P., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 5, p. 3054-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The prevalence of the metabolic syndrome in a danish population of women with previous gestational diabetes mellitus is three-fold higher than in the general population

    Lauenborg, J., Mathiesen, Elisabeth, Hansen, Torben, Glümer, C., Jørgensen, T., Borch-Johnsen, K., Hornnes, P., Pedersen, Oluf Borbye & Damm, Peter, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 7, p. 4004-10 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    alpha 2-AMPK knockout abolishes AICAR but not exercise training-induced GLUT4 and HKII protein expression in mouse skeletal muscle

    Jørgensen, Solvejg, Treebak, Jonas Thue, Viollet, B., Andreelli, F., Schjerling, Peter, Vaulont, S., Wojtaszewski, Jørgen F P & Richter, Erik A., 2005, In: FASEB Journal.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Glucagon-like peptide-2 (GLP-2) response to enteral intake in children during anti-cancer treatment

    Andreassen, B. U., Paerregaard, A., Schmiegelow, Kjeld, Rechnitzer, C., Heilman, C., Hartmann, Bolette, Holst, Jens Juul & Michaelsen, Kim F., Jan 2005, In: Journal of Pediatric Gastroenterology and Nutrition. 40, 1, p. 48-53 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    The morphogenetic MreBCD proteins of Escherichia coli form an essential membrane-bound complex

    Kruse, Thomas, Bork-Jensen, J. & Gerdes, K., Jan 2005, In: Molecular Microbiology. 55, 1, p. 78-89 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Tissue levels and post-prandial secretion of the intestinal growth factor, glucagon-like peptide-2, in controls and inflammatory bowel disease: comparison with peptide YY

    Schmidt, P. T., Ljung, T., Hartmann, Bolette, Hare, K. J., Holst, Jens Juul & Hellström, P. M., Feb 2005, In: European journal of gastroenterology & hepatology. 17, 2, p. 207-12 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Primaer hyperparatyroidisme--forekomst, symptomer, komplikationer og behandling

    Bollerslev, J., Ogard, C. G., Schwarz, Peter, drb459, drb459, Vestergaard, P. & drb459, drb459, 21 Feb 2005, In: Ugeskrift for Laeger. 167, 8, p. 910-4 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Nutrient-stimulated GLP-2 release and crypt cell proliferation in experimental short bowel syndrome

    Martin, G. R., Wallace, L. E., Hartmann, Bolette, Holst, Jens Juul, Demchyshyn, L., Toney, K. & Sigalet, D. L., Mar 2005, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 288, 3, p. G431-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma.

    Jensen, K., Manfra, D., Grisotto, M., Martin, A., Vassileva, G., Kelley, K., Schwartz, Thue W. & Lira, S., Mar 2005, In: Journal of immunology (Baltimore, Md. : 1950).

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Effect of three types of additives in poor solvent on preparation of sustained-release nitrendipine microspheres by the quasi-emulsion solvent diffusion method

    Yang, Mingshi, Cui, F., Fan, Yong, You, B., Ren, K., Feng, H. & Kawashima, Y., 1 Mar 2005, In: Journal of Drug Delivery Science and Technology. 15, 2, p. 129-135 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    PGC-1alpha Gly482Ser polymorphism associates with hypertension among Danish whites

    Andersen, G., Wegner, L., Jensen, D. P., Glümer, C., Tarnow, L., Drivsholm, Thomas, Poulsen, P., Hansen, S. K., Nielsen, E. D., Ek, J., Mouritzen, P., Vaag, A., Parving, H., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 1 Apr 2005, In: Hypertension. 45, 4, p. 565-70 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Parathyroid scintigraphy during hypocalcaemia in primary hyperparathyroidism

    Øgard, C. G., drb459, drb459, Thomsen, J. B., Jakobsen, H., Almdal, Thomas Peter, Nielsen, S. L. & drb459, drb459, May 2005, In: Clinical Physiology and Functional Imaging. 25, 3, p. 166-70 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Myocardial perfusion defects and the left ventricular ejection fraction disclosed by scintigraphy in patients with primary hyperparathyroidism

    Ogard, C. G., Søndergaard, S. B., drb459, drb459, Jakobsen, H., Nielsen, S. L. & drb459, drb459, Jul 2005, In: World Journal of Surgery. 29, 7, p. 914-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    The interaction between the adaptor protein APS and Enigma is involved in actin organisation

    Barrès, Romain, Gonzalez, T., Le Marchand-Brustel, Y. & Tanti, J., 15 Aug 2005, In: Experimental Cell Research. 308, 2, p. 334-44 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Pancreatic beta cells from db/db mice show cell-specific [Ca2+]i and NADH responses to glucose but not to alpha-ketoisocaproic acid

    Gustavsson, N., Larsson-Nyrén, G. & Lindström, P., Oct 2005, In: Pancreas. 31, 3, p. 242-50 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Improving the calculation of statistical significance in genome-wide scans

    Ängquist, Lars & Hössjer, O., 1 Oct 2005, In: Biostatistics. 6, 4, p. 520-538 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Increased plasma N-terminal pro-B-type natriuretic peptide and markers of inflammation related to atherosclerosis in patients with primary hyperparathyroidism

    Ogard, C. G., Engelmann, M. D., Kistorp, Caroline Michaela Nervil, Nielsen, S. L. & drb459, drb459, Nov 2005, In: Clinical Endocrinology. 63, 5, p. 493-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Growth Hormone Antagonists. A Pharmacological Tool in Present and Future Therapies

    Kopchick, J. J., Qiu, L., Gosney, E., Keller, C., Palmer, A. & Sankaran, S., 1 Dec 2005, The Somatotrophic Axis in Brain Function. Elsevier Science Inc., p. 313-326 14 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  55. 2006
  56. Published

    6-Acylamino-2-amino-4-methylquinolines as potent melanin-concentrating hormone 1 receptor antagonists

    Ulven, Trond, Little, P. B., Receveur, J., Frimurer, Thomas Michael, Rist, Ø., Nørregaard, P. K., Mathiesen, Jesper M. & Högberg, T., 2006, In: Bioorganic & Medicinal Chemistry Letters. 16, 4, p. 1070-1075 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    A novel -192c/g Mutation in the Proximal P2 Promoter of the Hepatocyte Nuclear Factor-4α Gene (HNF4A) Associates With Late-onset Diabetes

    Ek, J., Hansen, S. P., Lajer, M., Nicot, C., Boesgaard, T. W., Pruhova, S., Johansen, A., Albrechtsen, Anders, Yderstraede, K., Lauenborg, J., Parrizas, M., Boj, S. F., Jørgensen, T., Borch-Johnsen, K., Damm, Peter, Ferrer, J., Lebl, J., Pedersen, Oluf Borbye & Hansen, Torben, 2006, In: Diabetes. 55, 6, p. 1869-73 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits.

    Treebak, Jonas Thue, Glund, S., Deshmukh, Atul Shahaji, Klein, D. K., Long, Y. C., Jensen, Thomas Elbenhardt, Jørgensen, S. B., Viollet, B., Andersson, L., Neumann, D., Wallimann, T., Richter, Erik A., Chibalin, A. V., Zierath, J. R. & Wojtaszewski, Jørgen F P, 2006, In: Diabetes. 55, 7, p. 2051-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Association between neuromedin U gene variants and overweight and obesity

    Hainerová, I., Torekov, Signe Sørensen, Ek, J., Finková, M., Borch-Johnsen, K., Jørgensen, T., Madsen, O. D., Lebl, J., Hansen, Torben & Pedersen, Oluf Borbye, 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 12, p. 5057-63 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses

    Tsuchiya, T., Schwarz, P. E. H., Bosque-Plata, L. D., Geoffrey Hayes, M., Dina, C., Froguel, P., Wayne Towers, G., Fischer, S., Temelkova-Kurktschiev, T., Rietzsch, H., Graessler, J., Vcelák, J., Palyzová, D., Selisko, T., Bendlová, B., Schulze, J., Julius, U., Hanefeld, M., Weedon, M. N., Evans, J. C. & 12 others, Frayling, T. M., Hattersley, A. T., Orho-Melander, M., Groop, L., Malecki, M. T., Hansen, Torben, Pedersen, Oluf Borbye, Fingerlin, T. E., Boehnke, M., Hanis, C. L., Cox, N. J. & Bell, G. I., 2006, In: Molecular Genetics and Metabolism. 89, 1-2, p. 174-84 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Biases in the perceived timing of perisaccadic perceptual and motor events

    Yarrow, K., Whiteley, Louise, Haggard, P. & Rothwell, J. C., 2006, In: Attention, Perception & Psychophysics. 68, 7, p. 1217-26 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Body mass, fat-free body mass, and prognosis in patients with chronic obstructive pulmonary disease from a random population sample: findings from the Copenhagen City Heart Study

    Vestbo, J., Prescott, Eva, Almdal, Thomas Peter, Dahl, M., Nordestgaard, Børge, Andersen, T., Sørensen, Thorkild I.A. & Lange, Peter, 2006, In: American Journal of Respiratory and Critical Care Medicine. 173, 1, p. 79-83 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families

    Cheyssac, C., Dina, C., Leprêtre, F., Vasseur-Delannoy, V., Dechaume, A., Lobbens, S., Balkau, B., Ruiz, J., Charpentier, G., Pattou, F., Joly, E., Prentki, M., Hansen, Torben, Pedersen, Oluf Borbye, Vaxillaire, M. & Froguel, P., 2006, In: Diabetes. 55, 4, p. 1171-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Fedmens genetik

    Echwald, S. M., Larsen, P. J., Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2006, In: Ugeskrift for læger. 168, 2, p. 150-152 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Genetic polymorphisms and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets

    Sørensen, T. I. A., Boutin, P., Taylor, M. A., Larsen, L. H., Verdich, C., Petersen, L., Holst, C., Echwald, S. M., Dina, C., Toubro, S., Petersen, M., Polak, J., Clément, K., Martinez, J. A., Langin, D., Oppert, J-M., Stich, V., Macdonald, I., Arner, P., Saris, W. H. M. & 3 others, Pedersen, Oluf Borbye, Astrup, A. & Froguel, P., 2006, In: PLoS Clinical Trials. 12, 2, p. 1-14 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Genotype-by-nutrient interactions assessed in European obese women: a case-only study

    Santos, J. L., Boutin, P., Verdich, C., Holst, C., Larsen, L. H., Toubro, S., Dina, C., Saris, W. H. M., Blaak, E. E., Hoffstedt, J., Taylor, M. A., Polak, J., Clement, K., Langin, D., Astrup, A., Froguel, P., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A., Martinez, J. A. & NUGENOB* consortium, N. C., 2006, In: European Journal of Nutrition. 45, 8, p. 454-462 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies

    Huth, C., Heid, I. M., Vollmert, C., Gieger, C., Grallert, H., Wolford, J. K., Langer, B., Thorand, B., Klopp, N., Hamid, Y. H., Pedersen, O., Hansen, T., Lyssenko, V., Groop, L., Meisinger, C., Döring, A., Löwel, H., Lieb, W., Hengstenberg, C., Rathmann, W. & 25 others, Martin, S., Stephens, J. W., Ireland, H., Mather, H., Miller, G. J., Stringham, H. M., Boehnke, M., Tuomilehto, J., Boeing, H., Möhlig, M., Spranger, J., Pfeiffer, A., Wernstedt, I., Niklason, A., López-Bermejo, A., Fernández-Real, J., Hanson, R. L., Gallart, L., Vendrell, J., Tsiavou, A., Hatziagelaki, E., Humphries, S. E., Wichmann, H., Herder, C. & Illig, T., 2006, In: Diabetes. 55, 10, p. 2915-21 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Lens fluorescence in relation to glucose tolerance and genetic predisposition to type 2 diabetes mellitus in a population-based study

    Koefoed Theil, P., Kessel, Line, Hansen, Torben, Lund-Andersen, H., Pedersen, Oluf Borbye & Larsen, Michael, 2006, In: Current Eye Research. 31, 9, p. 733-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Molecular properties of adult mouse gastric and intestinal epithelial progenitors in their niches

    Giannakis, M., Stappenbeck, T. S., Mills, J. C., Leip, D. G., Lovett, M., Clifton, S. W., Ippolito, J. E., Glasscock, J. I., Arumugam, Mani, Brent, M. R. & Gordon, J. I., 2006, In: Journal of Biological Chemistry. 281, 16, p. 11292-300 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Molekylaer patogenese ved monogen og polygen fedme

    Larsen, P. J., Echwald, S. M., Sørensen, Thorkild I.A. & Pedersen, Oluf Borbye, 2006, In: Ugeskrift for Laeger. 168, 2, p. 152-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Monitoring kidney function in type 2 diabetic patients with incipient and overt diabetic nephropathy

    Rossing, Peter, Rossing, K., Gaede, P., Pedersen, Oluf Borbye & Parving, H., 2006, In: Diabetes Care. 29, 5, p. 1024-30 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits

    Ulven, Trond, Receveur, J., Grimstrup, M., Rist, Ø., Frimurer, Thomas Michael, Gerlach, L., Mathiesen, Jesper M., Kostenis, E., Uller, L. & Högberg, T., 2006, In: Journal of Medicinal Chemistry. 49, 23, p. 6638-6641 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    PROactive study

    Gaede, P., Parving, H. & Pedersen, Oluf Borbye, 2006, In: Lancet. 367, 9504, p. 23-4; author reply 26-7

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Pairagon+N-SCAN_EST: a model-based gene annotation pipeline

    Arumugam, Mani, Wei, C., Brown, R. H. & Brent, M. R., 2006, In: Genome Biology (Online Edition). 7 Suppl 1, p. S5.1-10

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Serum ionised calcium and cardiovascular disease in 45-years old men and women followed for 18 years

    Ogard, C. G., Petersen, Janne, Jørgensen, T., Almdal, Thomas Peter, drb459, drb459 & drb459, drb459, 2006, In: European Journal of Epidemiology. 21, 2, p. 123-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Spatial consequences of bridging the saccadic gap

    Yarrow, K., Whiteley, Louise, Rothwell, J. C. & Haggard, P., 2006, In: Vision Research. 46, 4, p. 545-55 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    The HADHSC gene encoding short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD) and type 2 diabetes susceptibility: the DAMAGE study

    van Hove, E. C., Hansen, Torben, Dekker, J. M., Reiling, E., Nijpels, G., Jørgensen, T., Borch-Johnsen, K., Hamid, Y. H., Heine, R. J., Pedersen, Oluf Borbye, Maassen, J. A. & hart, L. M., 2006, In: Diabetes. 55, 11, p. 3193-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Variants in the 5' region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects

    Torekov, Signe Sørensen, Larsen, L. H., Andersen, G., Albrechtsen, Anders, Glümer, C., Borch-Johnsen, K., Jørgensen, Tina, Hansen, Teis Schjals & Pedersen, Oluf Borbye, 2006, In: Diabetologia. 49, 11, p. 2653-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: studies in 6018 whites

    Jensen, D. P., Urhammer, S. A., Eiberg, Hans Rudolf Lytchoff, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2006, In: Molecular Genetics and Metabolism. 89, 4, p. 360-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Endocannabinoids

    Hansen, Harald S., Petersen, G., Artmann, A. & Madsen, A. N., 1 Jan 2006, In: European Journal of Lipid Science and Technology. 108, 10, p. 877-889 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Critical nodes in signalling pathways: insights into insulin action

    Taniguchi, C. M., Emanuelli, Brice & Kahn, C. R., Feb 2006, In: Nature Reviews. Molecular Cell Biology. 7, 2, p. 85-96 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Timing of Ca2+ response in pancreatic beta-cells is related to mitochondrial mass

    Gustavsson, N., Abedi, G., Larsson-Nyrén, G. & Lindström, P., 24 Feb 2006, In: Molecular Cell Biology Research Communications. 340, 4, p. 1119-24 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients

    Bouzakri, K., Karlsson, H. K. R., drb459, drb459, Madsbad, Sten, Christiansen, E. & Zierath, Juleen R, Mar 2006, In: Diabetes. 55, 3, p. 785-91 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    A liver specific gene that is expressed in growth hormone transgenic mice and in normal female mice as a function of age

    Tiong, J. D. R., Gosney, E., Ding, J., Chin, E. & Kopchick, J. J., 1 Jun 2006, In: Growth Hormone and IGF Research. 16, 3, p. 145-156 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Cell specificity of the cytoplasmic Ca2+ response to tolbutamide is impaired in beta-cells from hyperglycemic mice

    Gustavsson, N., Larsson-Nyrén, G. & Lindström, P., Aug 2006, In: The Journal of endocrinology. 190, 2, p. 461-70 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Mediastinalt parathyroideacysteadenom--en sjaelden årsag til primaer hyperparatyroidisme

    Øgard, C. G., Nielsen, S. L., Jakobsen, H., Leth-Espensen, P., drb459, drb459 & drb459, drb459, 28 Aug 2006, In: Ugeskrift for Laeger. 168, 35, p. 2921-2 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Enigma interacts with adaptor protein with PH and SH2 domains to control insulin-induced actin cytoskeleton remodeling and glucose transporter 4 translocation

    Barrès, Romain, Grémeaux, T., Gual, P., Gonzalez, T., Gugenheim, J., Tran, A., Le Marchand-Brustel, Y. & Tanti, J., Nov 2006, In: Molecular Endocrinology. 20, 11, p. 2864-75 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

    Lagouge, M., Argmann, C., Gerhart-Hines, Zach, Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., Geny, B., Laakso, M., Puigserver, P. & Auwerx, J., 15 Dec 2006, In: Cell. 127, 6, p. 1109-1122 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. 2007
  90. Published

    A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis

    Dahlman, I., Dicker, A., Jiao, H., Kere, J., Blomqvist, L., van Harmelen, V., Hoffstedt, J., Borch-Johnsen, K., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Laakso, M. & Arner, P., 2007, In: American Journal of Human Genetics. 80, 6, p. 1115-24 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

    Steinthorsdottir, V., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Jonsdottir, T., Walters, G. B., Styrkarsdottir, U., Gretarsdottir, S., Emilsson, V., Ghosh, S., Baker, A., Snorradottir, S., Bjarnason, H., Ng, M. C. Y., Hansen, T., Bagger, Y., Wilensky, R. L., Reilly, M. P., Adeyemo, A., Chen, Y. & 25 others, Zhou, J., Gudnason, V., Chen, G., Huang, H., Lashley, K., Doumatey, A., So, W., Ma, R. C. Y., Andersen, G., Borch-Johnsen, K., Jorgensen, T., van Vliet-Ostaptchouk, J. V., Hofker, M. H., Wijmenga, C., Christiansen, C., Rader, D. J., Rotimi, C., Gurney, M., Chan, J. C. N., Pedersen, Oluf Borbye, Sigurdsson, G., Gulcher, J. R., Thorsteinsdottir, U., Kong, A. & Stefansson, K., 2007, In: Nature Genetics. 39, 6, p. 770-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    AS160 phosphorylation is associated with activation of alpha(2)beta(2)gamma(1)- but not alpha(2)beta(2)gamma(3)-AMPK trimeric complex in skeletal muscle during exercise in humans

    Treebak, Jonas Thue, Birk, Jesper Bratz, Rose, A. J., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2007, In: American Journal of Physiology-Endocrinology and Metabolism.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Association between obesity and asthma in a twin cohort

    Thomsen, S., Ulrik, Charlotte Suppli, Kyvik, K., Sørensen, Thorkild I.A., Posthuma, D., Skadhauge, L., Steffensen, I. & Backer, V., 2007, In: Allergy. European Journal of Allergy and Clinical Immunology. 62, 10, p. 1199-1204 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population: studies of 7,495 Danish whites

    Wegner, L., Andersen, G., Sparsø, T., Grarup, Niels, Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetes. 56, 3, p. 694-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes

    Larsen, L. H., Rose, C. S., Sparsø, T., Overgaard, J., Torekov, Signe Sørensen, Grarup, Niels, Jensen, Dan Funck, Albrechtsen, Anders, Andersen, G., Ek, J., Glümer, C., Borch-Johnsen, K., Jørgensen, Tina, Hansen, Teis Schjals & Pedersen, Oluf Borbye, 2007, In: International Journal of Obesity. 31, 2, p. 365-70 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Glucagon-like peptide-2 in umbilical cord blood from mature infants

    Bodé, S., Hartmann, Bolette, Holst, Jens Juul & Greisen, Gorm, 2007, In: Neonatology. 91, 1, p. 49-53 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Hyperphosphorylation and low protein content of muscle glycogen synthase contribute to insulin resistance in polycystic ovary syndrome: effects of pioglitazone treatment

    Hojlund, K., Glintborg, D., Andersen, N. R., Birk, Jesper Bratz, Treebak, Jonas Thue, Beck-Nielsen, H. & Wojtaszewski, Jørgen F P, 2007, In: Diabetologia.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Phenoxyacetic acid derivatives as CRTH2 receptor ligands, their preparation, pharmaceutical compositions, and use in therapy

    Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E., Högberg, T., Receveur, J. & Grimstrup, M., 2007, Patent No. WO 2007/062678 A1

    Research output: Patent

  99. Published

    Pointwise and Genomewide Significance Calculations in Gene Mapping through Nonparametric Linkage Analysis: Theory, Algorithms and Applications

    Ängquist, Lars, 2007, 250 p.

    Research output: Book/Report › Ph.D. thesis › Research

  100. Published

    Pointwise and Genomewide Significance Calculations in Gene Mapping through Nonparametric Linkage Analysis: Theory, Algorithms and Applications (Summary)

    Ängquist, Lars, 2007, In: Qvartilen. 22, 2, p. 25-26

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy

    Kamiyama, M., Kobayashi, M., Araki, S., Iida, A., Tsunoda, T., Kawai, K., Imanishi, M., Nomura, M., Babazono, T., Iwamoto, Y., Kashiwagi, A., Kaku, K., Kawamori, R., Ng, D. P. K., Hansen, Torben, Gaede, P., Pedersen, Oluf Borbye, Nakamura, Y. & Maeda, S., 2007, In: Human Genetics. 122, 3-4, p. 397-407 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects

    Pedersen, N. B., Hjøllund, K. R., Johnsen, A. H., Ørskov, Cathrine, Rosenkilde, Mette, Hartmann, B. & Holst, Jens Juul, 2007, In: Regulatory Peptides. 146, 1-3, p. 310-320 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags

    Gorodkin, J., Cirera, S., Hedegaard, J., Gilchrist, M. J., Panitz, F., Jørgensen, C., Scheibye-Knudsen, K., Arvin, T., Lumholdt, S., Sawera, M., Green, T., Nielsen, B., Havgaard, J. H., Rosenkilde, C., Wang, J., Li, H., Li, R., Liu, B., Hu, S., Dong, W. & 16 others, Li, W., Yu, J., Wang, J., Staefeldt, H., Wernersson, R., Madsen, L. B., Thomsen, B. S., Hornshøj, H., Bujie, Z., Wang, X., Wang, X., Bolund, L., Brunak, Søren, Yang, H., Bendixen, C. & Fredholm, Merete, 2007, In: Genome Biology. 8, R45, p. R45 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. Published

    Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

    Helgason, A., Pálsson, S., Thorleifsson, G., Grant, S. F. A., Emilsson, V., Gunnarsdottir, S., Adeyemo, A., Chen, Y., Chen, G., Reynisdottir, I., Benediktsson, R., Hinney, A., Hansen, T., Andersen, G., Borch-Johnsen, K., Jorgensen, T., Schäfer, H., Faruque, M., Doumatey, A., Zhou, J. & 13 others, Wilensky, R. L., Reilly, M. P., Rader, D. J., Bagger, Y., Christiansen, C., Sigurdsson, G., Hebebrand, J., Pedersen, Oluf Borbye, Thorsteinsdottir, U., Gulcher, J. R., Kong, A., Rotimi, C. & Stefánsson, K., 2007, In: Nature Genetics. 39, 2, p. 218-25 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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