- Published
An RNA-seq atlas of mouse brain areas during fasting and diet-induced obesity
Todorov, Petar Vladimirov, Klein, A. B., Egerod, Kristoffer Lihme, Clemmensen, Christoffer & Pers, Tune H, 2024, In: Scientific Data. 11, 8 p., 44.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An abundant biliary fatty acid metabolite derived from dietary omega-3 polyunsaturated fatty acids regulates triglycerides
Grevengoed, Trisha Jean, Trammell, Sam, Svenningsen, J. S., Makarov, M., Nielsen, Thomas Svava, Jacobsen, Jens Christian Brings, Calder, P. C., Migaud, M. E., Cravatt, B. & Gillum, M. P., 2021, In: Journal of Clinical Investigation. 131, 6, 12 p., e143861.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An adiposity force induces obesity in humans independently of a normal energy balance system-a thought experiment
Sørensen, Thorkild I.A., 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 9 p., 20220203.Research output: Contribution to journal › Review › Research › peer-review
- Published
An adult-based genetic risk score for hepatic fat associates with liver and lipid traits in Danish children and adolescents
Huang, Yun, Stinson, Sara, Juel, H. B., Lund, Morten Asp Vonsild, Holm, L. A., Fonvig, Cilius Esmann, Grarup, Niels, Pedersen, Oluf Borbye, Christiansen, Michael, Krag, A., Stender, S., Holm, Jens-Christian & Hansen, Torben, 2022, In: Journal of Hepatology. 77, p. S450-S450 1 p., FRI104.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
An adult-based genetic risk score for liver fat associates with liver and plasma lipid traits in children and adolescents
Huang, Yun, Stinson, Sara, Juel, H. B., Lund, M. A. V., Holm, Louise Aas, Fonvig, Cilius Esmann, Nielsen, T., Grarup, Niels, Pedersen, Oluf Borbye, Christiansen, M., Chabanova, E., Thomsen, Henrik S., Krag, A., Stender, S., Holm, Jens-Christian & Hansen, Torben, 2023, In: Liver International. 43, 8, p. 1772-1782 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese
Graae, A. S., Hollensted, M., Kloppenborg, J. T., Mahendran, Y., Schnurr, T. M., Appel, E. V. R., Rask, J., Nielsen, T. R. H., Johansen, M., Linneberg, Allan René, Jørgensen, M. E., Grarup, Niels, Kadarmideen, H. N., Holst, Birgitte, Pedersen, Oluf Borbye, Holm, Jens-Christian & Hansen, Torben, Aug 2018, In: Diabetologia. 61, 8, p. 1769-1779Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise
Ziegler, A. K., Damgaard, A., Mackey, Abigail, Schjerling, Peter, Magnusson, Stig Peter, Olesen, A. T., Kjær, Michael & Schéele, Camilla Charlotte Nielsen, 2019, In: Scientific Reports. 9, 11 p., 12069.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor
Els, S., Schild, E., Petersen, P. S., Kilian, T., Mokrosinski, J., Frimurer, Thomas Michael, Chollet, C., Schwartz, Thue W., Holst, Birgitte & Beck-Sickinger, A. G., 13 Sep 2012, In: Journal of Medicinal Chemistry. 55, 17, p. 7437-49 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles
Madsen, Thomas Daugbjerg, Hansen, L. H., Hintze, John, Ye, Z., Jebari, S., Andersen, Daniel Bjørklund, Joshi, Hiren Jitendra, Ju, T., Goetze, Jens P. , Martin, C., Rosenkilde, Mette, Holst, Jens Juul, Kuhre, Rune Ehrenreich, Goth, C. K., Vakhrushev, Sergey & Schjoldager, Katrine Ter-Borch Gram, 2020, In: Nature Communications. 11, 1, 13 p., 4033.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An automated workflow for multi-omics screening of microbial model organisms
Donati, S., Mattanovich, M., Hjort, P., Jacobsen, S. A. B., Blomquist, S. D., Mangaard, D., Gurdo, N., Pastor, F. P., Maury, J., Hanke, R., Herrgård, M. J., Wulff, T., Jakočiūnas, T., Nielsen, L. K. & McCloskey, D., 2023, In: npj Systems Biology and Applications. 9, 12 p., 14.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An effort to use human-based exome capture methods to analyze chimpanzee and macaque exomes
Jin, X., He, M., Ferguson, B., Meng, Y., Ouyang, L., Ren, J., Mailund, T., Sun, F., Sun, L., Shen, J., Zhuo, M., Song, L., Wang, J., Ling, F., Zhu, Y., Hvilsom, C., Siegismund, H. R., Liu, X., Gong, Z., Ji, F. & 15 others, , 2012, In: P L o S One. 7, 7, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An integrated catalog of reference genes in the human gut microbiome
Li, J., Jia, H., Cai, X., Zhong, H., Feng, Q., Sunagawa, S., Arumugam, M., Kultima, J. R., Prifti, E., Nielsen, T., Juncker, A., Manichanh, C., Chen, B., Zhang, W., Levenez, F., Wang, J., Xu, X., Xiao, L., Liang, S., Zhang, D. & 17 others, , 2014, In: Nature Biotechnology. 32, 8, p. 834-845 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins
Yuan, W., Xia, Y., Bell, C. G., Yet, I., Ferreira, T., Ward, K. J., Gao, F., Loomis, A. K., Hyde, C. L., Wu, H., Lu, H., Liu, Y., Small, K. S., Vinuela, A., Morris, A. P., Berdasco, M., Esteller, M., Brosnan, M. J., Deloukas, P., McCarthy, M. I. & 4 others, , 2014, In: Nature Communications. 5, 7 p., 5719.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An integrated model of obesity pathogenesis that revisits causal direction
Ludwig, D. S. & Sørensen, Thorkild I.A., 2022, In: Nature Reviews Endocrinology. 18, p. 261-262 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
An integrated tool to study MHC region: accurate SNV detection and HLA genes typing in human MHC region using targeted high-throughput sequencing
Cao, H., Wu, J., Wang, Y., Jiang, H., Zhang, T., Liu, X., Xu, Y., Liang, D., Gao, P., Sun, Y., Gifford, B., D'Ascenzo, M., Liu, X., Tellier, L. C. A. M., Yang, F., Tong, X., Chen, D., Zheng, J., Li, W., Richmond, T. & 3 others, , 2013, In: P L o S One. 8, 7, 9 p., e69388.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
An integrative framework to prioritize genes in more than 500 loci associated with body mass index
Hemerich, D., Svenstrup, Victor, Díez Obrero, Virginia, Preuss, M. H., Moscati, A., Hirschhorn, J. N. & Loos, Ruth, 9 May 2024, (E-pub ahead of print) In: American Journal of Human Genetics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
Hansen, Stine Lind, Larsen, Hjalte List, Pikkupeura, Laura Maarit, Maciag, Grzegorz Jerzy, Guiu, J., Müller, I., Clement, Ditte Lynge, Mueller, C., Johansen, Jens Vilstrup, Helin, K., Lerdrup, Mads & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 18 p., eadg4055.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An overview of obesity mechanisms in humans: Endocrine regulation of food intake, eating behaviour and common determinants of body weight
Theilade, Karen Simone, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetes, Obesity and Metabolism. 23, S1, p. 17-35 19 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
An overview of once-weekly glucagon-like peptide-1 receptor agonists--available efficacy and safety data and perspectives for the future
Madsbad, Sten, Kielgast, U., Asmar, M., Deacon, Carolyn F., Torekov, Signe Sørensen & Holst, Jens Juul, May 2011, In: Diabetes, Obesity and Metabolism. 13, 5, p. 394-407 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anaemia in the first trimester and poor physiological plasma expansion during pregnancy negatively impact foetal weight and newborn anthropometrics: An observational cohort study in Tanzania
Schmiegelow, Christentze, Møller, S. L., Yde, A. M., Nielsen, B. B., Hjort, Line, Theander, Thor Grundtvig, Lusingu, J. P. A., Minja, D. T. R. & Bygbjerg, Ib Christian, 2024, In: Tropical Medicine & International Health. 29, 3, p. 243-255 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analyses of single nucleotide polymorphisms in selected nutrient-sensitive genes in weight-regain prevention: the DIOGENES study
Larsen, L. H., Ängquist, Lars, Vimaleswaran, K. S., Hager, J., Viguerie, N., Loos, Ruth, Handjieva-Darlenska, T., Jebb, S. A., Kunesova, M., Larsen, T. M., Martinez, J. A., Papadaki, A., Pfeiffer, A. F. H., van Baak, M. A., Sørensen, Thorkild I.A., Holst, C., Langin, D., Astrup, A. & Saris, W. H. M., 2012, In: American Journal of Clinical Nutrition. 95, 5, p. 1254-1260 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion
Skov, L., Schierup, M. H., Danish Pan Genome Consortium, D. P. G. C., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Rasmussen, Simon, Kristiansen, Karsten & Brunak, Søren, 2017, In: PLOS Genetics. 13, 8, p. e1006834Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of Case-Parent Trios Using a Loglinear Model with Adjustment for Transmission Ratio Distortion
Huang, L. O., Infante-RIvard, C. & Labbe, A., Aug 2016, In: Frontiers in Genetics. 7, p. 1-10 10 p., 155.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude
Kadalayil, L., Alam, M. Z., White, C. H., Ghantous, A., Walton, E., Gruzieva, O., Merid, S. K., Kumar, A., Roy, R. P., Solomon, O., Huen, K., Eskenazi, B., Rzehak, P., Grote, V., Langhendries, J. P., Verduci, E., Ferre, N., Gruszfeld, D., Gao, L., Guan, W. & 83 others, , 2023, In: Clinical Epigenetics. 15, 23 p., 148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of case-parent trios for imprinting effect using a loglinear model with adjustment for sex-of-parent-specific transmission ratio distortion
Huang, L. O., Infante-Rivard, C. & Labbe, A., Aug 2017, In: Human Genetics. 136, 8, p. 951-961 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
Ellinghaus, D., Jostins, L., Spain, S. L., Cortes, A., Bethune, J., Han, B., Park, Y. R., Raychaudhuri, S., Pouget, J. G., Hübenthal, M., Folseraas, T., Wang, Y., Esko, T., Metspalu, A., Westra, H-J., Franke, L., Pers, T. H., Weersma, R. K., Collij, V., D'Amato, M. & 26 others, , May 2016, In: Nature Genetics. 48, 5, p. 510-521 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of sequential hair segments reflects changes in the metabolome across the trimesters of pregnancy
Delplancke, T. D. J., de Seymour, J. V., Tong, C., Sulek, K., Xia, Y., Zhang, H., Han, T. & Baker, P. N., 2018, In: Scientific Reports. 8, p. 1-12 36.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase
Shehata, S. N., Hunter, R. W., Ohta, E., Peggie, M. W., Lou, H. J., Sicheri, F., Zeqiraj, E., Turk, B. E. & Sakamoto, Kei, 1 Nov 2012, In: Cellular Signalling. 24, 11, p. 2085-2094 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits—The Hispanic/Latino Anthropometry Consortium
Fernández-Rhodes, L., Graff, M., Buchanan, V. L., Justice, A. E., Highland, H. M., Guo, X., Zhu, W., Chen, H. H., Young, K. L., Adhikari, K., Palmer, N. D., Below, J. E., Bradfield, J., Pereira, A. C., Glover, L. S., Kim, D., Lilly, A. G., Shrestha, P., Thomas, A. G., Zhang, X. & 96 others, , 2022, In: Human Genetics and Genomics Advances. 3, 2, 21 p., 100099.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancestral diversity in lipoprotein(a) studies helps address evidence gaps
Lee, M. P., Dimos, S. F., Raffield, L. M., Wang, Z., Ballou, A. F., Downie, C. G., Arehart, C. H., Correa, A., De Vries, P. S., Du, Z., Gignoux, C. R., Gordon-Larsen, P., Guo, X., Haessler, J., Howard, A. G., Hu, Y., Kassahun, H., Kent, S. T., Lopez, J. A. G., Monda, K. L. & 14 others, , 2023, In: Open Heart. 10, 2, 11 p., e002382.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression
Wang, Q., Bailey, C. G., Ng, C., Tiffen, J., Thoeng, A., Minhas, V., Lehman, M. L., Hendy, S. C., Buchanan, G., Nelson, C. C., Rasko, J. E. J., Holst, J. & Holst, Jens Juul, 2011, In: Cancer Research. 71, 24, p. 7525-7536 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Animal models of mucositis: critical tools for advancing pathobiological understanding and identifying therapeutic targets
Wardill, H. R., Tissing, W. J. E., Kissow, Hannelouise & Stringer, A. M., 2019, In: Current Opinion in Supportive and Palliative Care. 13, 2, p. 119-133Research output: Contribution to journal › Review › Research › peer-review
- Published
Anorexia and fat aversion induced by vertical sleeve gastrectomy is attenuated in neurotensin receptor 1–Deficient mice
Ratner, C., Shin, J. H., Dwibedi, C., Tremaroli, V., Bjerregaard, Anette, Hartmann, Bolette, Bäckhed, F., Leinninger, G., Seeley, R. J. & Holst, Birgitte, 2021, In: Endocrinology. 162, 9, 12 p., bqab130.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R-dependent manner
Jepsen, Sara Lind, Albrechtsen, Nicolai Jacob Wewer, Windeløv, Johanne Agerlin, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Farb, T. B., Kissow, Hannelouise, Pedersen, J., Deacon, Carolyn F., Martin, R. E. & Holst, Jens Juul, 2021, In: JCI insight. 6, 4, 15 p., e143228.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-Obesity Therapy: from Rainbow Pills to Polyagonists.
Müller, T., Clemmensen, Christoffer, Finan, B., DiMarchi, R. & Tschöp, M., Oct 2018, In: Pharmacological Reviews.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-inflammatory effects of active commuting and leisure time exercise in overweight and obese women and men: A randomized controlled trial
Gram, A. S., Bladbjerg, E., Quist, Jonas Salling, Blond, Martin Bæk, Rosenkilde, M. & Stallknecht, Bente Merete, Oct 2017, In: Atherosclerosis. 265, p. 318-324 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-inflammatory properties of a novel peptide interleukin 1 receptor antagonist
Klementiev, B., Li, S., Korshunova, Irina, Dmytriyeva, O., Pankratova, Stanislava, Walmod, P. S., Kjær, L. K., Dahllöf, M. S., Lundh, M., Christensen, D. P., Mandrup-Poulsen, Thomas, Bock, E. & Berezin, V., 2014, In: Journal of Neuroinflammation. 11, 1, p. 27Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic exposure in early life and childhood overweight and obesity: A systematic review and meta-analysis
Rasmussen, S. H., Shrestha, S., Bjerregaard, L. G., Ängquist, Lars, Baker, J. L., Jess, T. & Allin, K. H., 2018, In: Diabetes, Obesity and Metabolism. 20, 6, p. 1508–1514Research output: Contribution to journal › Review › Research › peer-review
- Published
Antibiotic treatment during early childhood and risk of type 1 diabetes in children: A national birth cohort study
Antvorskov, J. C., Morgen, C. S., Buschard, K., Jess, T., Allin, K. H. & Josefsen, K., 2020, In: Pediatric Diabetes. 21, 8, p. 1457-1464Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic use during pregnancy and childhood overweight: A population-based nationwide cohort study
Jess, T., Morgen, C. S., Harpsoe, M. C., Sørensen, Thorkild I.A., Ajslev, T. A., Antvorskov, J. C. & Allin, K. H., 2019, In: Scientific Reports. 9, 9 p., 11528 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice
Livanos, A. E., Greiner, T. U., Vangay, P., Pathmasiri, W., Stewart, D., McRitchie, S., Li, H., Chung, J., Sohn, J., Kim, S., Gao, Z., Barber, C., Kim, J., Ng, S., Rogers, A. B., Sumner, S., Zhang, X-S., Cadwell, K., Knights, D., Alekseyenko, A. & 2 others, , 22 Aug 2016, In: Nature Microbiology. 1, 11, p. 1-13 13 p., 16140.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotics during childhood and development of appendicitis—a nationwide cohort study
Antonsen, J., Hansen, S., Morgen, C. S., Jess, T., Jørgensen, Lars Nannestad & Allin, K. H., 2021, In: Alimentary Pharmacology and Therapeutics. 53, 1, p. 87-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anticholinergic medication exposure predicts poor physical capability: Findings from a large prospective cohort study in England
Yrjana, K. R., Keevil, V. L., Soiza, R. L., Luben, R. N., Wareham, N. J., Khaw, K. & Myint, P. K., 1 Dec 2020, In: Maturitas. 142, p. 55-63Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetes Agents and Incident Depression: A Nationwide Population-Based Study
Kessing, Lars Vedel, Rytgaard, Helene Charlotte Wiese, Ekstrøm, Claus Thorn, Knop, Filip Krag, Berk, M. & Gerds, Thomas Alexander, 2020, In: Diabetes Care. 43, 12, p. 3050-3060Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual ß-cell function
Kielgast, U., Holst, Jens Juul & Madsbad, Sten, May 2011, In: Diabetes. 60, 5, p. 1599-1607 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetogenic Effect of glucagon-like peptide-1 (7-36) amide in normal subjects and patients with diabetes mellitus
Gutniak, M., Ørskov, Cathrine, Holst, Jens Juul, Ahrén, B. & Efendic, S., 1992, In: New England Journal of Medicine. 326, p. 1316-1322Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antifibrotic and molecular aspects of rifaximin in alcoholic liver disease: study protocol for a randomized controlled trial
Madsen, B. S., Trebicka, J., Thiele, M., Israelsen, M., Arumugam, Mani, Havelund, T. & Krag, A., 2018, In: Trials. 19, p. 1-5 5 p., 143.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antigenicity and immunogenicity of recombinant glutamate-rich protein of Plasmodium falciparum expressed in Escherichia coli
Theisen, Michael, Vuust, J., Gottschau, A., Jepsen, S. & Høgh, Birthe, Jan 1995, In: Clinical and Vaccine Immunology. 2, 1, p. 30-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antihypertensive treatment of end-stage renal disease patients on hemodialysis does not alter circulating ACE and ACE2 activity and angiotensin peptides
Gomes, R. V. C., Peluso, A. A., Ronchi, F. A., de Oliveira, L. C. G., Casarini, D. E., Santos, R. A. S., Endlich, P. W. & de Abreu, G. R., 2024, In: American Journal of the Medical Sciences. 367, 2, p. 128-134Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
Schafer, Z. T., Grassian, A. R., Song, L., Jiang, Z., Gerhart-Hines, Zach, Irie, H. Y., Gao, S., Puigserver, P. & Brugge, J. S., 3 Sep 2009, In: Nature. 461, 7260, p. 109-113 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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An integrative framework to prioritize genes in more than 500 loci associated with body mass index
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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