Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2024
  2. E-pub ahead of print

    An integrative framework to prioritize genes in more than 500 loci associated with body mass index

    Hemerich, D., Svenstrup, Victor, Díez Obrero, Virginia, Preuss, M. H., Moscati, A., Hirschhorn, J. N. & Loos, Ruth, 9 May 2024, (E-pub ahead of print) In: American Journal of Human Genetics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The use of a systems approach to increase NAD+ in human participants

    Henderson, John David, Quigley, S. N. Z., Chachra, S. S., Conlon, N. & Ford, D., 2024, In: npj Aging. 10, 12 p., 7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Genome-wide association study of preserved ratio impaired spirometry (PRISm)

    Higbee, D. H., Lirio, A., Hamilton, F., Granell, R., Wyss, A. B., London, S. J., Bartz, T. M., Gharib, S. A., Cho, M. H., Wan, E., Silverman, E., Crapo, J. D., Lominchar, J. V. T., Hansen, T., Grarup, N., Dantoft, T., Kårhus, L., Linneberg, A., O'Connor, G. T., Dupuis, J. & 25 others, Xu, H., De Vries, M. M., Hu, X., Rich, S. S., Barr, R. G., Manichaikul, A., Wijnant, S. R. A., Brusselle, G. G., Lahousse, L., Li, X., Hernández Cordero, A. I., Obeidat, M., Sin, D. D., Harris, S. E., Redmond, P., Taylor, A. M., Cox, S. R., Williams, A. T., Shrine, N., John, C., Guyatt, A. L., Hall, I. P., Davey Smith, G., Tobin, M. D. & Dodd, J. W., 2024, In: European Respiratory Journal. 63, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Epigenetics of the non-coding RNA nc886 across blood, adipose tissue and skeletal muscle in offspring exposed to diabetes in pregnancy

    Hjort, Line, Bredgaard, S. S., Manitta, Eleonora, Marques, I., Sørensen, A. E., Martino, D., Grunnet, Louise Groth, Kelstrup, Louise, Houshmand-Oeregaard, A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Olsen, S. F., Saffery, R., Barrès, Romain, Damm, Peter, Vaag, A. A. & Dalgaard, L. T., 2024, In: Clinical Epigenetics. 16, 1, 15 p., 61.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    New Lessons from the gut: Studies of the role of gut peptides in weight loss and diabetes resolution after gastric bypass and sleeve gastrectomy

    Holst, Jens Juul, Madsbad, Sten, Bojsen-Møller, Kirstine Nyvold, Dirksen, C. & Svane, M., 2024, In: Peptides. 176, 9 p., 171199.

    Research output: Contribution to journalReviewResearchpeer-review

  7. E-pub ahead of print

    Functional genomic screens with death rate analyses reveal mechanisms of drug action

    Honeywell, M. E., Isidor, Marie Sophie, Harper, N. W., Fontana, R. E., Birdsall, G. A., Cruz-Gordillo, P., Porto, S. A., Jerome, M., Fraser, C. S., Sarosiek, K. A., Guertin, D. A., Spinelli, J. B. & Lee, M. J., 2024, (E-pub ahead of print) In: Nature Chemical Biology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Human Genetic Variation at rs10071329 Correlates with Adiposity-related Traits, Modulates PPARGC1B Expression, and Alters Brown Adipocyte Function

    Huang, M., Prasad, R. B., Coral, D. E., Hjort, Line, Minja, D. T. R., Mulder, H., Franks, P. W. & Kalamajski, S., 2024, In: Diabetes. 73, 4, p. 637-645

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Dietary impact on fasting and stimulated GLP-1 secretion in different metabolic conditions - a narrative review

    Huber, H., Schieren, A., Holst, Jens Juul & Simon, M., 2024, In: The American Journal of Clinical Nutrition. 119, 3, p. 599-627

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas

    Hughes, O., Bentley, A. R., Breeze, C. E., Aguet, F., Xu, X., Nadkarni, G., Sun, Q., Lin, B. M., Gilliland, T., Meyer, M. C., Du, J., Raffield, L. M., Kramer, H., Morton, R. W., Gouveia, M. H., Atkinson, E. G., Valladares-Salgado, A., Wacher-Rodarte, N., Dueker, N. D., Guo, X. & 54 others, Hai, Y., Adeyemo, A., Best, L. G., Cai, J., Chen, G., Chong, M., Doumatey, A., Eales, J., Goodarzi, M. O., Ipp, E., Irvin, M. R., Jiang, M., Jones, A. C., Kooperberg, C., Krieger, J. E., Lange, E. M., Lanktree, M. B., Lash, J. P., Lotufo, P. A., Loos, Ruth, Ha My, V. T., Peralta-Romero, J., Qi, L., Raffel, L. J., Rich, S. S., Rodriquez, E. J., Tarazona-Santos, E., Taylor, K. D., Umans, J. G., Wen, J., Young, B. A., Yu, Z., Zhang, Y., Ida Chen, Y. D., Rundek, T., Rotter, J. I., Cruz, M., Fornage, M., Lima-Costa, M. F., Pereira, A. C., Paré, G., Natarajan, P., Cole, S. A., Carson, A. P., Lange, L. A., Li, Y., Perez-Stable, E. J., Do, R., Charchar, F. J., Tomaszewski, M., Mychaleckyj, J. C., Rotimi, C., Morris, A. P. & Franceschini, N., 2024, In: Cell Genomics. 4, 1, 13 p., 100468.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. E-pub ahead of print

    Introduction: Laboratory times

    Hussey, Kristin D. & Douglas-Jones, R., 2024, (E-pub ahead of print) In: Time & Society.

    Research output: Contribution to journalJournal articleResearch

  12. E-pub ahead of print

    Z-Time: Making and feeling time in the chronobiological laboratory

    Hussey, Kristin D., 2024, (E-pub ahead of print) In: Time & Society.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Persistent thinness and anorexia nervosa differ on a genomic level

    Hübel, C., Abdulkadir, M., Herle, M., Palmos, A. B., Loos, Ruth, Breen, G., Micali, Nadia & Bulik, C. M., 2024, In: European Journal of Human Genetics. 32, 1, p. 117-124

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Impact of acute alcohol consumption on circulating microbiome in asymptomatic alcohol-related liver disease

    Israelsen, M., Alvarez Silva, Maria Camila, Madsen, B. S., Hansen, C. D., Torp, N. C., Johansen, S., Hansen, J. K., Prier Lindvig, K., Insonere, J., Riviere, V., Juel, H. B., Brejnrod, A., Jensen, Lars Juhl, Thiele, M., Lelouvier, B., Hansen, Torben, Arumugam, Mani & Krag, A., 2024, In: Gut. 73, 6, p. 1041-1044 gutjnl-2023-330360.

    Research output: Contribution to journalLetterResearchpeer-review

  15. Published
  16. Published

    Infections increase the risk of decompensation and death in patients with early alcohol-related liver disease

    Johansen, S., Langkjær, S., Rasmussen, D. N., Israelsen, M., Torp, N., Lindvig, K., Kjærgaard, M., Hansen, J. K., Hansen, C. D., Thorhauge, K., Andersen, P., Detlefsen, S., Juel, H. B., Justesen, U. S., Hansen, Torben, Krag, A., Thiele, M., GALAXY and MicrobLiver consortia, G. A. M. C. & MicrobLiver Consortium, M. C., 2024, In: JHEP Reports. 6, 4, 10 p., 101016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Change in abdominal obesity after colon cancer surgery – effects of left-sided and right-sided colonic resection

    Kays Mohammed Ali, Y., Dolin, T. G., Damm Nybing, J., Lykke, J., Hvid Linden, F., Høgh-Schmidt, E., Sørensen, Thorkild I.A., Christensen, J. F., Nielsen, Yousef Jesper Wirenfeldt, Stenfatt Larsen, J., Madsbad, Sten, Johansen, Julia Sidenius, Svane, M. S. & Lang Lehrskov, L., 2024, In: International Journal of Obesity. 48, 4, p. 533-541 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits

    Million Veteran Program, M. V. P., LifeLines Cohort Study, L. C. S., CHARGE Consortium, C. C. & ICBP Consortium, I. C., 2024, In: Nature Genetics. 56, 5, p. 778-791

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Sociodemographic characteristics and COVID-19 testing rates: spatiotemporal patterns and impact of test accessibility in Sweden

    Kennedy, B., Varotsis, G., Hammar, U., Nguyen, D., Carrasquilla, Germán D., van Zoest, V., Kristiansson, R. S., Fitipaldi, H., Dekkers, K. F., Daivadanam, M., Martinell, M., Björk, J. & Fall, T., 2024, In: European Journal of Public Health. 34, 1, p. 14-21

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood donors

    Kjerulff, B., Dowsett, J., Jacobsen, R. L., Gladov, J., Larsen, M. H., Lundgaard, A. T., Banasik, K., Westergaard, D., Mikkelsen, S., Dinh, K. M., Hindhede, L., Kaspersen, K. A., Schwinn, M., Juul, A., Poulsen, B., Lindegaard, B., Pedersen, C. B., Sabel, C. E., Bundgaard, H., Nielsen, H. S. & 30 others, Møller, J. A., Boldsen, J. K., Burgdorf, Kristoffer Sølvsten, Kessing, Lars Vedel, Handgaard, L. J., Thørner, L. W., Didriksen, Maria, Nyegaard, Mette, Grarup, Niels, Ødum, Niels, Johansson, P. I., Jennum, Poul, Frikke-Schmidt, Ruth, Berger, S. S., Brunak, Søren, Jacobsen, Søren, Hansen, Thomas Folkmann, Lundquist, T. K., Hansen, Torben, Sørensen, Torben Lykke, Sigsgaard, T., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Ullum, H., Rostgaard, K., Sørensen, E., Pedersen, Ole Birger Vesterager, Ostrowski, Sisse Rye & Erikstrup, C., 2024, In: Communications Medicine. 4, 15 p., 50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. E-pub ahead of print

    Gluco-Metabolic response to EXOGENOUS oxytocin in TOTALLY pancreatectomized patients and HEALTHY INDIVIDUALS

    Kliim-Hansen, V., Gether, I. M., Juel, C. T., Ellegaard, A., Pedersen, M. G., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Lund, Asger Bach, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2024, (E-pub ahead of print) In: Peptides. 171242.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Low sphingolipid levels predict poor survival in patients with alcohol-related liver disease

    Kronborg, T. M., Gao, Q., Trošt, K., Lambert, Henriette Ytting, O'Connell, M. B., Werge, M. P., Thing, M., Gluud, Lise Lotte, Hamberg, O., Møller, Søren, Moritz, Thomas, Bendtsen, Flemming & Kimer, N., 2024, In: JHEP Reports. 6, 2, 15 p., 100953.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Harnessing the power of proteomics in precision diabetes medicine

    Kurgan, Nigel Kilty, Larsen, Jeppe Kjærgaard & Deshmukh, Atul Shahaji, 2024, In: Diabetologia. 67, 5, p. 783–797

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    The AMPK-related kinase NUAK1 controls cortical axons branching by locally modulating mitochondrial metabolic functions

    Lanfranchi, M., Yandiev, S., Meyer-Dilhet, G., Ellouze, S., Kerkhofs, M., Dos Reis, R., Garcia, A., Blondet, C., Amar, A., Kneppers, A., Polvèche, H., Plassard, D., Foretz, M., Viollet, B., Sakamoto, Kei, Mounier, R., Bourgeois, C. F., Raineteau, O., Goillot, E. & Courchet, J., 2024, In: Nature Communications. 15, 17 p., 2487.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations

    Lennon, N. J., Kottyan, L. C., Kachulis, C., Abul-Husn, N. S., Arias, J., Belbin, G., Below, J. E., Berndt, S. I., Chung, W. K., Cimino, J. J., Clayton, E. W., Connolly, J. J., Crosslin, D. R., Dikilitas, O., Velez Edwards, D. R., Feng, Q. P., Fisher, M., Freimuth, R. R., Ge, T., Glessner, J. T. & 59 others, Gordon, A. S., Patterson, C., Hakonarson, H., Harden, M., Harr, M., Hirschhorn, J., Hoggart, C., Hsu, L., Irvin, M. R., Jarvik, G. P., Karlson, E. W., Khan, A., Khera, A., Kiryluk, K., Kullo, I., Larkin, K., Limdi, N., Linder, J. E., Loos, Ruth, Luo, Y., Malolepsza, E., Manolio, T. A., Martin, L. J., McCarthy, L., McNally, E. M., Meigs, J. B., Mersha, T. B., Mosley, J. D., Musick, A., Namjou, B., Pai, N., Pesce, L. L., Peters, U., Peterson, J. F., Prows, C. A., Puckelwartz, M. J., Rehm, H. L., Roden, D. M., Rosenthal, E. A., Rowley, R., Sawicki, K. T., Schaid, D. J., Smit, Roelof Adriaan Johan, Smith, J. L., Smoller, J. W., Thomas, M., Tiwari, H., Toledo, D. M., Vaitinadin, N. S., Veenstra, D., Walunas, T. L., Wang, Z., Wei, W. Q., Weng, C., Wiesner, G. L., Yin, X., Kenny, E. E., Berndt, S. & Hirschhorn, J., 2024, In: Nature Medicine. 30, 2, p. 480-487 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Introgression and disruption of migration routes have shaped the genetic integrity of wildebeest populations

    Liu, X., Lin, L., Sinding, M. H. S., Bertola, L. D., Hanghøj, K., Quinn, L., Garcia-Erill, G., Rasmussen, M. S., Schubert, M., Pečnerová, P., Balboa, R. F., Li, Z., Heaton, M. P., Smith, T. P. L., Pinto, R. R., Wang, X., Kuja, J., Brüniche-Olsen, A., Meisner, J., Santander, C. G. & 8 others, Ogutu, J. O., Masembe, C., Rodrigues da Fonseca, Rute Andreia, Muwanika, V., Siegismund, Hans Redlef, Albrechtsen, Anders, Moltke, Ida & Heller, Rasmus, 2024, In: Nature Communications. 15, 1, 16 p., 2921.

    Research output: Contribution to journalJournal articleResearchpeer-review

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