- 2024
- Published
Development of an automated, high-throughput assay to detect angiotensin AT2-receptor agonistic compounds by nitric oxide measurements in vitro
Souza-Silva, I. M., Peluso, A. A., Mortensen, C., Nazarova, A. L., Stage, T. B., Sumners, C., Katritch, V. & Steckelings, U. M., 2024, In: Peptides. 172, 7 p., 171137.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications
Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., Åsvold, B. O., Bandinelli, S., Beekman, M., Beilby, J. P., Bork-Jensen, J., Boutin, T., Brody, J. A., Brown, S. J., Brumpton, B., Campbell, P. J. & 121 others, , 2024, In: Nature Communications. 15, 1, 18 p., 888.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered Glucagon and GLP-1 Responses to Oral Glucose in Children and Adolescents With Obesity and Insulin Resistance
Stinson, Sara, Fernández de Retana Alzola, I., Hovendal, Emilie Damgaard Brünner, Lund, Morten Asp Vonsild, Fonvig, Cilius Esmann, Holm, Louise Aas, Jonsson, Anna Elisabet, Frithioff-Bøjsøe, C., Christiansen, Michael, Pedersen, Oluf Borbye, Ängquist, Lars, Sørensen, T. I. A., Holst, Jens Juul, Hartmann, Bolette, Holm, Jens-Christian & Hansen, Torben, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 6, p. 1590-1600 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Extended Minimal Model of OGTT: estimation of α- and β-cell dysfunction, insulin resistance, and the incretin effect
Subramanian, V., Bagger, J. I., Harihar, V., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2024, In: American Journal of Physiology - Endocrinology and Metabolism. 326, 2, p. E182-E205Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Genetic underpinnings of fasting and oral glucose-stimulated based insulin sensitivity indices
Suleman, Sufyan, Madsen, Anne Lundager, Ängquist, Lars, Schubert, Mikkel, Linneberg, Allan René, Loos, Ruth, Hansen, Torben & Grarup, Niels, 2024, (Accepted/In press) In: Journal of Clinical Endocrinology and Metabolism.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MagicalRsq-X: A cross-cohort transferable genotype imputation quality metric
Sun, Q., Yang, Y., Rosen, J. D., Chen, J., Li, X., Guan, W., Jiang, M-Z., Wen, J., Pace, R. G., Blackman, S. M., Bamshad, M. J., Gibson, R. L., Cutting, G. R., O'Neal, W. K., Knowles, M. R., Kooperberg, C., Reiner, A. P., Raffield, L. M., Carson, A. P., Rich, S. S. & 7 others, , 2024, In: American Journal of Human Genetics. 111, 5, p. 990-995 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Signs of Glucagon Resistance After a Two-Week Hypercaloric Diet Intervention
Suppli, M. P., Høgedal, A., Bagger, J. I., Chabanova, E., van Hall, Gerrit, Forman, Julie Lyng, Christensen, Mikkel Bring, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Knop, Filip Krag, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 4, p. 955–967 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., Rayner, N. W., Bocher, O., Arruda, A. L., Sonehara, K., Namba, S., Lee, S. S. K., Preuss, M. H., Petty, L. E., Schroeder, P., Vanderwerff, B. & 31 others, , 2024, In: Nature. 627, 8003, p. 347-357 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Association between recent exposure to continuous glucose monitoring-recorded hypoglycaemia and counterregulatory and symptom responses to subsequent controlled hypoglycaemia in people with type 1 diabetes
Svensson, C. H., Fabricius, T. W., Verhulst, C. E. M., Kristensen, Peter Lommer, Tack, C. J., Heller, S. R., Amiel, S. A., McCrimmon, R. J., Evans, M., Holst, Jens Juul, de Galan, B. E. & Pedersen-Bjergaard, Ulrik, 2024, (E-pub ahead of print) In: Diabetes, Obesity and Metabolism.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prognostic Value of Gut Microbe-Generated Metabolite Phenylacetylglutamine in Patients with Heart Failure
Tang, W. H. W., Nemet, I., Li, X. S., Wu, Y., Haghikia, A., Witkowski, M., Koeth, R. A., Demuth, I., König, M., Steinhagen-Thiessen, E., Bäckhed, F., Fischbach, M. A., Deb, A., Landmesser, U. & Hazen, S. L., 2024, In: European Journal of Heart Failure. 26, 2, p. 233-241Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Consumption of Olive Oil and Diet Quality and Risk of Dementia-Related Death
Tessier, A. J., Cortese, M., Yuan, C., Bjornevik, K., Ascherio, A., Wang, D. D., Chavarro, J. E., Stampfer, M. J., Hu, F. B., Willett, W. C. & Guasch Ferre, Marta, 2024, In: JAMA network open. 7, 5, 13 p., E2410021.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma metabolites of a healthy lifestyle in relation to mortality and longevity: Four prospective US cohort studies
Tessier, A. J., Wang, F., Liang, L., Wittenbecher, C., Haslam, D. E., Eliassen, A. H., Tobias, D. K., Li, J., Zeleznik, O. A., Ascherio, A., Sun, Q., Stampfer, M. J., Grodstein, F., Rexrode, K. M., Manson, J. A. E., Balasubramanian, R., Clish, C. B., Martínez-González, M. A., Chavarro, J. E., Hu, F. B. & 1 others, , 2024, In: Med. 5, 3, p. 224-238.e5 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Opportunities and barriers in omics-based biomarker discovery for steatotic liver diseases
Thiele, M., Villesen, I. F., Niu, L., Johansen, S., Sulek, K., Nishijima, S., Espen, L. V., Keller, M., Israelsen, M., Suvitaival, T., Zawadzki, A. D., Juel, H. B., Brol, M. J., Stinson, S. E., Huang, Y., Silva, M. C. A., Kuhn, M., Anastasiadou, E., Leeming, D. J., Karsdal, M. & 12 others, , 2024, (E-pub ahead of print) In: Journal of Hepatology.Research output: Contribution to journal › Review › Research › peer-review
- Published
Variants at the Interleukin 1 Gene Locus and Pericarditis
Thorolfsdottir, R. B., Jonsdottir, A. B., Sveinbjornsson, G., Aegisdottir, H. M., Oddsson, A., Stefansson, O. A., Halldorsson, G. H., Saevarsdottir, S., Thorleifsson, G., Stefansdottir, L., Pedersen, O. B., Sørensen, E., Ghouse, J., Raja, A. A., Zheng, C., Silajdzija, E., Rand, S. A., Erikstrup, C., Ullum, H., Mikkelsen, C. & 26 others, , 2024, In: JAMA Cardiology. 9, 2, p. 165-172 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An RNA-seq atlas of mouse brain areas during fasting and diet-induced obesity
Todorov, Petar Vladimirov, Klein, A. B., Egerod, Kristoffer Lihme, Clemmensen, Christoffer & Pers, Tune H, 2024, In: Scientific Data. 11, 8 p., 44.Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Bitter taste receptors: Key target to understand the effects of polyphenols on glucose and body weight homeostasis. Pathophysiological and pharmacological implications
Trius-Soler, Marta & Moreno, J. J., 2024, (Accepted/In press) In: Biochemical Pharmacology. 116192.Research output: Contribution to journal › Review › Research › peer-review
- Published
High-density lipoprotein functionality, cardiovascular health, and patterns of alcohol consumption: new insights and future perspectives
Trius-Soler, Marta, Mukamal, K. J. & Guasch Ferre, Marta, 2024, In: Current Opinion in Lipidology. 35, 1, p. 25-32 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b
Uehara, K., Lee, W. D., Stefkovich, M., Biswas, Dipsikha, Santoleri, D., Whitlock, A. G., Quinn, W., Coopersmith, T., Creasy, K. T., Rader, D. J., Sakamoto, Kei, Rabinowitz, J. D. & Titchenell, P. M., 2024, In: Journal of Clinical Investigation. 134, 7, 13 p., e173782.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscle
Voisin, S., Seale, K., Jacques, M., Landen, S., Harvey, N. R., Haupt, L. M., Griffiths, L. R., Ashton, K. J., Coffey, V. G., Thompson, J. L. M., Doering, T. M., Lindholm, M. E., Walsh, C., Davison, G., Irwin, R., McBride, C., Hansson, O., Asplund, O., Heikkinen, A. E., Piirilä, P. & 7 others, , 2024, In: Aging Cell. 23, 1, 15 p., e13859.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise-induced increase in muscle insulin sensitivity in men is amplified when assessed using a meal test
Voldstedlund, Christian T, Sjøberg, K. A., Schlabs, Farina Leonie, Sigvardsen, Casper Møller, Andersen, Nicoline Resen, Holst, Jens Juul, Hartmann, Bolette, Wojtaszewski, Jørgen F P, Kiens, Bente, McConell, G. K. & Richter, Erik A., 2024, In: Diabetologia. 67, p. 1386–1398Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical exome sequencing reveals a novel pathogenic variant in KIF12 underlying cholestasis with highly variable phenotypes
Waheed, N., Waris, R., Naseer, M., Razzaq, A., Suleman, Sufyan & Ullah, A., 2024, In: Clinical Genetics. 105, 1, p. 106-108Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Production of deoxycholic acid by low-abundant microbial species is associated with impaired glucose metabolism
Wahlström, A., Brumbaugh, A., Sjöland, W., Olsson, L., Wu, H., Henricsson, M., Lundqvist, A., Makki, K., Hazen, S. L., Bergström, G., Marschall, H. U., Fischbach, M. A. & Bäckhed, F., 2024, In: Nature Communications. 15, 11 p., 4276.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Welsh, J. A., Goberdhan, D. C. I., O’Driscoll, L., Buzas, E. I., Blenkiron, C., Bussolati, B., Cai, H., Di Vizio, D., Driedonks, T. A. P., Erdbrügger, U., Falcon-Perez, J. M., Fu, Q. L., Hill, A. F., Lenassi, M., Lim, S. K., Mahoney, M. Ỹ. G., Mohanty, S., Möller, A., Nieuwland, R., Ochiya, T. & 31 others, , 2024, In: Journal of Extracellular Vesicles. 13, 2, 84 p., e12404.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Childhood adversity trajectories and weight status in young adult men: a register-based study including 359,783 Danish men
Wimmelmann, Cathrine Lawaetz, Sejling, Christoffer, Clarke, Rebecca B, Elsenburg, Leonie K., Sørensen, Thorkild I.A. & Rod, Naja Hulvej, 2024, (E-pub ahead of print) In: International journal of obesity (2005).Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
Winther-Sørensen, Marie, Garcia, S. L., Bartholdy, Andreas, Ottenheijm, Maud Eline, Banasik, Karina, Brunak, Søren, Sorensen, Charlotte Mehlin, Gluud, Lise Lotte, Knop, Filip Krag, Holst, Jens Juul, Rosenkilde, Mette, Jensen, Majken Karoline & Albrechtsen, Nicolai Jacob Wewer, 6 May 2024, (E-pub ahead of print) In: Diabetologia.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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Aficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy
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An integrative framework to prioritize genes in more than 500 loci associated with body mass index
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
Research output: Contribution to journal › Journal article › Research › peer-review