Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2022
  2. Published

    Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite–binding site

    Sanders, M. J., Ratinaud, Y., Neopane, K., Bonhoure, N., Day, E. A., Ciclet, O., Lassueur, S., Pinta, M. N., Deak, M., Brinon, B., Christen, S., Steinberg, G. R., Barron, D. & Sakamoto, Kei, 2022, In: Journal of Biological Chemistry. 298, 5, 15 p., 101852.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis

    Sato, S., Dyar, K. A., Treebak, J. T., Jepsen, S. L., Ehrlich, A. M., Ashcroft, S. P., Trost, K., Kunzke, T., Prade, V. M., Small, L., Basse, A. L., Schönke, M., Chen, S., Samad, M., Baldi, P., Barrès, R., Walch, A., Moritz, T., Holst, J. J., Lutter, D. & 2 others, Zierath, Juleen R & Sassone-Corsi, P., 2022, In: Cell Metabolism. 34, 2, p. 329-345.e8 26 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Exercise timing influences multi-tissue metabolome and skeletal muscle proteome profiles in type 2 diabetic patients - A randomized crossover trial

    Savikj, M., Stocks, Ben Nicholas, Sato, S., Caidahl, K., Krook, A., Deshmukh, Atul Shahaji, Zierath, Juleen R & Wallberg-Henriksson, H., 2022, In: Metabolism. 135, 14 p., 155268.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Can we target obesity using a single-cell atlas of adipose tissue?

    Schéele, Camilla Charlotte Nielsen & Nielsen, S., 2022, In: Med. 3, 5, p. 276-278 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  6. Published

    Isolation and Characterization of Human Brown Adipocytes

    Schéele, Camilla Charlotte Nielsen, Henriksen, T. I. & Nielsen, S., 2022, In: Methods in Molecular Biology. 2448, p. 217-234 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Segmental reversal of the distal small intestine in a short bowel syndrome model in piglets showed detrimental effect on weight gain

    Schmidt, L. H., Aa, J. S., Hartmann, Bolette, Madsen, G. I., Qvist, N. & Ellebæk, M. B., 2022, In: BMC Gastroenterology. 22, 1, 9 p., 349.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Interactions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD

    Schnurr, T. M., Katz, S. F., Justesen, Johanne Marie, O'Sullivan, J. W., Saliba-Gustafsson, P., Assimes, T. L., Carcamo-Orive, I., Ahmed, A., Ashley, E. A., Hansen, Torben & Knowles, J. W., 2022, In: Hepatology Communications. 6, 7, p. 1516-1526

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Smoking during pregnancy is associated with child overweight independent of maternal pre-pregnancy BMI and genetic predisposition to adiposity

    Schnurr, T. M., Ängquist, Lars, Nohr, E. A., Hansen, Torben, Sørensen, Thorkild I.A. & Morgen, C. S., 2022, In: Scientific Reports. 12, 1, 10 p., 3135.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling

    Segref, A., Vakkayil, K. L., Padvitski, T., Li, Q., Kroef, V., Lormann, J., Körner, L., Finger, Fabian Michael & Hoppe, T., 2022, In: Nature Communications. 13, 1, 17 p., 5874.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Whole genome sequence analysis of blood lipid levels in >66,000 individuals

    Selvaraj, M. S., Li, X., Li, Z., Pampana, A., Zhang, D. Y., Park, J., Aslibekyan, S., Bis, J. C., Brody, J. A., Cade, B. E., Chuang, L. M., Chung, R. H., Curran, J. E., de las Fuentes, L., de Vries, P. S., Duggirala, R., Freedman, B. I., Graff, M., Guo, X., Heard-Costa, N. & 27 others, Hidalgo, B., Hwu, C. M., Irvin, M. R., Kelly, T. N., Kral, B. G., Lange, L., Li, X., Lisa, M., Lubitz, S. A., Manichaikul, A. W., Michael, P., Montasser, M. E., Morrison, A. C., Naseri, T., O’Connell, J. R., Palmer, N. D., Peyser, P. A., Reupena, M. S., Smith, J. A., Sun, X., Taylor, K. D., Tracy, R. P., Tsai, M. Y., Wang, Z., Wang, Y., Loos, Ruth & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2022, In: Nature Communications. 13, 18 p., 5995.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Molecular Insights into the Role of Pathogenic nsSNPs in GRIN2B Gene Provoking Neurodevelopmental Disorders

    Shah, A. A., Amjad, M., Hassan, J. U., Ullah, A., Mahmood, A., Deng, H., Ali, Y., Gul, F. & Xia, K., 2022, In: Genes. 13, 8, 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    GLP-1 effect on ß-cell function varies according to diabetes remission status after RYGB

    Shah, A., Prasad, M., Mark, V., Holst, Jens Juul & Laferrère, B., 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2081-2089

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Changing genetic architecture of body mass index from infancy to early adulthood: an individual based pooled analysis of 25 twin cohorts

    Silventoinen, K., Li, W., Jelenkovic, A., Sund, R., Yokoyama, Y., Aaltonen, S., Piirtola, M., Sugawara, M., Tanaka, M., Matsumoto, S., Baker, L. A., Tuvblad, C., Tynelius, P., Rasmussen, F., Craig, J. M., Saffery, R., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Martin, N. G. & 37 others, Medland, S. E., Montgomery, G. W., Lichtenstein, P., Krueger, R. F., McGue, M., Pahlen, S., Christensen, K., Skytthe, A., Kyvik, K. O., Saudino, K. J., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Ullemar, V., Almqvist, C., Magnusson, P. K. E., Corley, R. P., Huibregtse, B. M., Knafo-Noam, A., Mankuta, D., Abramson, L., Haworth, C. M. A., Plomin, R., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Duncan, G. E., Buchwald, D., Burt, S. A., Klump, K. L., Llewellyn, C. H., Fisher, A., Boomsma, D., Sørensen, Thorkild I.A. & Kaprio, J., 2022, In: International Journal of Obesity. 46, p. 1901–1909 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Smoking remains associated with education after controlling for social background and genetic factors in a study of 18 twin cohorts

    Silventoinen, K., Piirtola, M., Jelenkovic, A., Sund, R., Tarnoki, A. D., Tarnoki, D. L., Medda, E., Nisticò, L., Toccaceli, V., Honda, C., Inui, F., Tomizawa, R., Watanabe, M., Sakai, N., Gatz, M., Butler, D. A., Lee, J., Lee, S. J., Sung, J., Franz, C. E. & 31 others, Kremen, W. S., Lyons, M. J., Derom, C. A., Vlietinck, R. F., Loos, Ruth, Tynelius, P., Rasmussen, F., Martin, N. G., Medland, S. E., Montgomery, G. W., Brandt, I., Nilsen, T. S., Harris, J. R., Tyler, J., Hopper, J. L., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Rebato, E., Zhang, D., Pang, Z., Tan, Q., Silberg, J. L., Maes, H. H., Boomsma, D. I., Sørensen, Thorkild I.A., Korhonen, T. & Kaprio, J., 2022, In: Scientific Reports. 12, 1, 9 p., 13148.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Exome Sequencing Revealed a Novel Splice Site Variant in the CRB2 Gene Underlying Nephrotic Syndrome

    Simaab, A., Krishin, J., Alaradi, S. R., Haider, N., Shah, M., Ullah, A., Abdullah, A., Ahmad, W., Hansen, Torben & Basit, S., 2022, In: Medicina. 58, 12, 9 p., 1784.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Association of milk intake with hay fever, asthma, and lung function: a Mendelian randomization analysis

    Skaaby, T., Kilpeläinen, Tuomas O., Mahendran, Y., Huang, L. O., Sallis, H., Thuesen, B. H., Kårhus, L. L., Leth-Møller, K. B., Grarup, Niels, Hansen, Torben, Pedersen, Oluf Borbye, Burgess, S., Munafò, M. R. & Linneberg, Allan René, 2022, In: European Journal of Epidemiology. 37, p. 713-722

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes

    Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K., Grove, J., Albiñana, C., Geller, F., Bjurström, C. F., Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V., Erikstrup, C., Westergaard, D., Nielsen, K. R. & 19 others, Sørensen, E., Bruun, M. T., Liu, X., Hjalgrim, Henrik, Pers, Tune H, Mortensen, P. B., Mors, O., Nordentoft, Merete, Dreier, J. W., Børglum, A. D., Christensen, J., Hougaard, D. M., Buil, A., Hviid, Anders Peter, Melbye, M., Ullum, H., Berkovic, S. F., Werge, Thomas & Feenstra, B., 2022, In: Brain. 145, 2, p. 555–568

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Comparative analysis of oral and intraperitoneal glucose tolerance tests in mice

    Small, Lewin Barkla, Ehrlich, Amy M, Iversen, Jo Frøkjær, Ashcroft, Stephen Paul, Trošt, K., Moritz, Thomas, Hartmann, Bolette, Holst, Jens Juul, Treebak, Jonas Thue, Zierath, Juleen R & Barrès, Romain, 2022, In: Molecular Metabolism. 57, 8 p., 101440.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response

    Snieckute, Goda, Genzor Garbayo, Aitana Victoria, Vind, Anna Constance, Jordan, Laura Ryder, Stoneley, M., Chamois, S., Dreos, R., Nordgaard, C., Sass, Frederike, Blasius, Melanie, López, A. R., Brynjólfsdóttir, S. H., Andersen, Kasper Langebjerg, Willis, A. E., Frankel, Lisa, Poulsen, Steen Seier, Gatfield, D., Gerhart-Hines, Zach, Clemmensen, Christoffer & Bekker-Jensen, Simon Holst, 2022, In: Cell Metabolism. 34, 12, p. 2036-2046.e8 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation

    Solomon, O., Huen, K., Yousefi, P., Küpers, L. K., González, J. R., Suderman, M., Reese, S. E., Page, C. M., Gruzieva, O., Rzehak, P., Gao, L., Bakulski, K. M., Novoloaca, A., Allard, C., Pappa, I., Llambrich, M., Vives, M., Jima, D. D., Kvist, T., Baccarelli, A. & 65 others, White, C., Rezwan, F. I., Sharp, G. C., Tindula, G., Bergström, A., Grote, V., Dou, J. F., Isaevska, E., Magnus, M. C., Corpeleijn, E., Perron, P., Jaddoe, V. W. V., Nohr, E. A., Maitre, L., Foraster, M., Hoyo, C., Håberg, S. E., Lahti, J., DeMeo, D. L., Zhang, H., Karmaus, W., Kull, I., Koletzko, B., Feinberg, J. I., Gagliardi, L., Bouchard, L., Ramlau-Hansen, C. H., Tiemeier, H., Santorelli, G., Maguire, R. L., Czamara, D., Litonjua, A. A., Langhendries, J. P., Plusquin, M., Lepeule, J., Binder, E. B., Verduci, E., Dwyer, T., Carracedo, Á., Ferre, N., Eskenazi, B., Kogevinas, M., Nawrot, T. S., Munthe-Kaas, M. C., Herceg, Z., Relton, C., Melén, E., Gruszfeld, D., Breton, C., Fallin, M. D., Ghantous, A., Nystad, W., Heude, B., Snieder, H., Hivert, M. F., Felix, J. F., Sørensen, Thorkild I.A., Bustamante, M., Murphy, S. K., Raikkönen, K., Oken, E., Holloway, J. W., Arshad, S. H., London, S. J. & Holland, N., 2022, In: Mutation Research - Reviews in Mutation Research. 789, 108415.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    Plasma FGF21 concentrations are regulated by glucose independently of insulin and GLP-1 in lean, healthy humans

    Solomon, T. P. J., Carter, S., Haus, J. M., Karstoft, Kristian, Holstein-Rønsbo, Stephanie, Nielsen, M. S. & Gillum, M. P., 2022, In: PeerJ. 10, 16 p., e12755.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Staying strong during hibernation

    Sommer, F. & Bäckhed, F., 2022, In: Science. 375, 6579, p. 376-377 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Himalayan bacterial endophytes enhance microalgal cell numbers and chlorophyll content in synthetic co-culture

    Sonowal, S., Palani, Nagendra Prasad, Ahmed, R., Debbarma, J., Chikkaputtaiah, C., Basar, E. & Velmurugan, N., 2022, In: Journal of Applied Phycology. 34, 5, p. 2383-2400

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published
  26. Published
  27. Published

    Hyperglucagonemia in pediatric adiposity associates with cardiometabolic risk factors but not hyperglycemia

    Stinson, Sara, Jonsson, Anna Elisabet, Alzola, I. F. D. R., Lund, Morten Asp Vonsild, Frithioff-Bøjsøe, C., Holm, L. A., Fonvig, Cilius Esmann, Pedersen, Oluf Borbye, Ängquist, Lars, Sørensen, Thorkild I.A., Holst, Jens Juul, Christiansen, M., Holm, Jens-Christian, Hartmann, Bolette & Hansen, Torben, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 6, p. 1569–1576

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Integrated Liver and Plasma Proteomics in Obese Mice Reveals Complex Metabolic Regulation

    Stocks, Ben Nicholas, Gonzalez-Franquesa, A., Borg, M. L., Björnholm, M., Niu, Lili, Zierath, Juleen R & Deshmukh, Atul Shahaji, 2022, In: Molecular and Cellular Proteomics. 21, 3, 19 p., 100207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Post-translational modifications: The signals at the intersection of exercise, glucose uptake and insulin sensitivity

    Stocks, Ben Nicholas & Zierath, Juleen R, 2022, In: Endocrine Reviews. 43, 4, p. 654-677 24 p.

    Research output: Contribution to journalReviewResearchpeer-review

  30. Published

    A glucose-insulin-glucagon coupled model of the isoglycemic intravenous glucose infusion experiment

    Subramanian, V., Bagger, J. I., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Frontiers in Physiology. 13, 20 p., 911616.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Four weeks treatment with the GLP-1 receptor analogue liraglutide lowers liver fat and concomitantly circulating glucagon in individuals with overweight

    Svane, M. S., Johannesen, H. H., Hansen, Adam Espe, Martinussen, C., Bojsen-Møller, K. N., Hansen, M. L., Deacon, Carolyn F., Keller, S. H., Klausen, Thomas Levin, Loft, A., Kjær, Andreas, Löfgren, J., Madsbad, Sten, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: International Journal of Obesity. 46, 11, p. 2058–2062 8 p.

    Research output: Contribution to journalLetterResearchpeer-review

  32. Published

    Neurotensin secretion after Roux-en-Y gastric bypass, sleeve gastrectomy, and truncal vagotomy with pyloroplasty

    Svane, M. S., Øhrstrøm, C. C., Plamboeck, A., Jørgensen, Nils Bruun, Bojsen-Møller, K. N., Dirksen, C., Martinussen, C., Vilsbøll, Tina, Hartmann, Bolette, Deacon, Carolyn F., Kristiansen, V. B., Knop, Filip Krag, Svendsen, Lars Bo, Madsbad, Sten, Holst, Jens Juul & Veedfald, Simon, 2022, In: Neurogastroenterology and Motility. 34, 1, e14210.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Leveraging GPCR signaling in thermogenic fat to counteract metabolic diseases

    Sveidahl Johansen, O., Ma, Tao & Gerhart-Hines, Zach, 2022, In: Molecular Metabolism. 60, 8 p., 101474.

    Research output: Contribution to journalReviewResearchpeer-review

  34. Published

    Do gene-environment interactions have implications for the precision prevention of type 2 diabetes?

    Sørensen, Thorkild I.A., Metz, Sophia & Kilpeläinen, Tuomas O., 2022, In: Diabetologia. 65, p. 1804–1813 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  35. Published

    Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease

    Talmor-Barkan, Y., Bar, N., Shaul, A. A., Shahaf, N., Godneva, A., Bussi, Y., Lotan-Pompan, M., Weinberger, A., Shechter, A., Chezar-Azerrad, C., Arow, Z., Hammer, Y., Chechi, K., Forslund, S. K., Fromentin, S., Dumas, M. E., Ehrlich, S. D., Pedersen, Oluf Borbye, Kornowski, R. & Segal, E., 2022, In: Nature Medicine. 28, 2, p. 295-302 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction

    Tang, X., Rönnberg, E., Säfholm, J., Thulasingam, M., Trauelsen, Mette, Schwartz, Thue W., Wheelock, C. E., Dahlén, S. E., Nilsson, G. & Haeggström, J. Z., 2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 77, 9, p. 2677-2687

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Metabolite G-protein coupled receptor signaling: Potential regulation of eicosanoids

    Tang, X., Hou, Y., Schwartz, Thue W. & Haeggström, J. Z., 2022, In: Biochemical Pharmacology. 204, 7 p., 115208.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Role of endogenous incretins in the regulation of postprandial lipoprotein metabolism

    Taskinen, M., Matikainen, N., Björnson, E., Söderlund, S., Ainola, M., Hakkarainen, A., Lundbom, N., Sihlbom, C., Thorsell, A., Andersson, L., Adiels, M., Hartmann, Bolette, Deacon, Carolyn F., Holst, Jens Juul, Packard, C. J. & Borén, J., 2022, In: European Journal of Endocrinology. 187, 1, p. 75-84 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The Role of D-allulose and Erythritol on the Activity of the Gut Sweet Taste Receptor and Gastrointestinal Satiation Hormone Release in Humans: A Randomized, Controlled Trial

    Teysseire, F., Bordier, V., Budzinska, A., Weltens, N., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Beglinger, C., Van Oudenhove, L., Wölnerhanssen, B. K. & Meyer-Gerspach, A. C., 2022, In: Journal of Nutrition. 152, 5, p. 1228–1238,

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    DeepFake electrocardiograms: the key for open science for artificial intelligence in medicine

    Thambawita, V., Isaksen, Jonas L., Hicks, S. A., Ghouse, Jonas, Ahlberg, Gustav, Linneberg, Allan René, Grarup, Niels, Ellervik, Christina, Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., Holstein-Rathlou, N., Strümke, I., Hammer, H. L., Maleckar, M., Halvorsen, P., Riegler, M. A. & Kanters, Jørgen K., 2022, 17 p. (medRxiv).

    Research output: Working paperPreprint

  41. Published
  42. Published

    Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes: A randomised controlled trial

    Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Chabanova, E., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Haugaard, Steen Bendix & Krarup, T., 2022, In: Diabetologia. 65, p. 506-517 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Long-term outcomes of dietary carbohydrate restriction for HbA1c reduction in type 2 diabetes mellitus are needed. Reply to Kang J and Ma E [letter]

    Thomsen, M. N., Astrup, A., Holst, Jens Juul, Madsbad, Sten, Magkos, Faidon, Haugaard, Steen Bendix & Krarup, T., 2022, In: Diabetologia. 65, 6, p. 1060-1062 3 p.

    Research output: Contribution to journalComment/debateResearch

  44. Published

    Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial

    Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2022, In: Frontiers in Nutrition. 9, 14 p., 933118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Asthma and Wheeze Severity and the Oropharyngeal Microbiota in Children and Adolescents

    Thorsen, J., Stokholm, J., Rasmussen, M. A., Roggenbuck-Wedemeyer, M., Vissing, N. H., Mortensen, M. S., Brejnrod, A. D., Fleming, L., Bush, A., Roberts, G., Singer, F., Frey, U., Hedlin, G., Nordlund, B., Murray, C. S., Abdel-Aziz, M. I., Hashimoto, S., van Aalderen, W., Maitland-van der Zee, A. H., Shaw, D. & 13 others, Fowler, S. J., Sousa, A., Sterk, P. J., Chung, K. F., Adcock, I. M., Djukanovic, R., Auffray, C., Bansal, A. T., Wagers, S., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Sørensen, Søren Johannes & Bisgaard, H., 2022, In: Annals of the American Thoracic Society. 19, 12, p. 2031-2043 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Successful treatment of psoriasis with adalimumab induced no changes in the gut microbiota

    Todberg, T., Egeberg, Alexander, Zachariae, Claus, Sørensen, N., Pedersen, Oluf Borbye & Skov, Lone, 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 6, p. e464-e467 4 p.

    Research output: Contribution to journalComment/debateResearch

  47. Published

    Patients with psoriasis have a dysbiotic taxonomic and functional gut microbiota

    Todberg, T., Egeberg, Alexander, Zachariae, Claus, Sørensen, N., Pedersen, Oluf Borbye & Skov, Lone, 2022, In: British Journal of Dermatology. 187, 1, p. 89-98

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Binge drinking induces an acute burst of markers of hepatic fibrogenesis (PRO-C3)

    Torp, N., Israelsen, M., Nielsen, M. J., Åstrand, C. P., Juhl, P., Johansen, S., Hansen, C. D., Madsen, B., Villesen, I. F., Leeming, D. J., Thiele, M., Hansen, Torben, Karsdal, M. & Krag, A., 2022, In: Liver International. 42, 1, p. 92-101

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Dynamic interplay between Afadin S1795 phosphorylation and diet regulates glucose homeostasis in obese mice

    Tozzi, M., Brown, E. L., Petersen, P. S., Lundh, M., Isidor, Marie Sophie, Plucinska, Kaja, Nielsen, Thomas Svava, Agueda Oyarzabal, Marina, Small, Lewin Barkla, Treebak, Jonas Thue & Emanuelli, Brice, 2022, In: The Journal of Physiology. 600, 4, p. 885-902

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Scale in the history of medicine

    Tybjerg, Karin, 2022, In: Studies in History and Philosophy of Science. 91, p. 221-233 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    With obesity becoming the new normal, what should we do? Volume II

    Tziomalos, K., Kilpeläinen, Tuomas O. & Samaras, K., 2022, In: Frontiers in Endocrinology. 13, 3 p., 1119910.

    Research output: Contribution to journalEditorialResearch

  52. Published

    A novel nonsense variant in EXOC8 underlies a neurodevelopmental disorder

    Ullah, A., Krishin, J., Haider, N., Aurangzeb, B., Abdullah, Suleman, Sufyan, Ahmad, W., Hansen, Torben & Basit, S., 2022, In: Neurogenetics. 23, p. 203-212

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Clinical and genetic characterization of patients segregating variants in KPTN, MINPP1, NGLY1, AP4B1, and SON underlying neurodevelopmental disorders: Genetic and phenotypic expansion

    Ullah, A., Shah, A. A., Alluqmani, M., Haider, N., Aman, H., Alfadhli, F., Almatrafi, A. M., Albalawi, A. M., Krishin, J., Ullah Khan, F., Anjam, B. A., Abdullah, Peña Lozano, Elionora, Samad, A., Ahmad, W., Hansen, Torben, Xia, K. & Basit, S., 2022, In: International Journal of Developmental Neuroscience. 82, 8, p. 788-804

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Vagal afferent cholecystokinin receptor activation is required for glucagon-like peptide-1–induced satiation

    Vana, V., Lærke, M. K., Rehfeld, Jens Frederik, Arnold, M., Dmytriyeva, O., Langhans, W., Schwartz, Thue W. & Hansen, Harald S., 2022, In: Diabetes, Obesity and Metabolism. 24, 2, p. 268-280

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Entero-pancreatic hormone secretion, gastric emptying and glucose absorption after frequently sampled meal tests

    Veedfald, Simon, Rehfeld, Jens Frederik, van Hall, Gerrit, Svendsen, Lars Bo & Holst, Jens Juul, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 1, p. e188-e204 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Changes in BMI and physical activity from youth to adulthood distinguish normal-weight, metabolically obese adults from those who remain healthy

    Viitasalo, A., Pahkala, K., Lehtimäki, T., Viikari, J. S. A., Tammelin, T. H., Raitakari, O. & Kilpeläinen, Tuomas O., 2022, In: Frontiers in Endocrinology. 13, 7 p., 923327.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Endurance Training in Humans Modulates the Bacterial DNA Signature of Skeletal Muscle

    Villarroel, J., Donkin, I., Champion, C., Burcelin, R. & Barrès, Romain, 2022, In: Biomedicines. 10, 1, 15 p., 64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes

    Vogelezang, S., Bradfield, J. P., Early Growth Genetics Consortium, Ahluwalia, T. V. S., Liu, X., Schnurr, T. M., Frithioff-Bøjsøe, C., Bønnelykke, K., Lind, M. V., Lauritzen, L., Michaelsen, K. F., Lund, M. A. V., Melbye, M., Morgen, C. S., Pedersen, O. B., Holm, J-C., Grarup, N., Hansen, T., Nohr, E. A., Bisgaard, H. & 3 others, Grant, S. F. A., Felix, J. F. & Jaddoe, V. W. V., 2022, In: BMC Medical Genomics. 15, 16 p., 124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Exercise effects on γ3-AMPK activity, Akt substrate of 160 kDa phosphorylation, and glucose uptake in muscle of normal and insulin-resistant female rats

    Wang, H., Arias, E. B., Treebak, Jonas Thue & Cartee, G. D., 2022, In: Journal of Applied Physiology. 132, 1, p. 140-153 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Sucrose synthase activity is not required for cellulose biosynthesis in Arabidopsis

    Wang, W., Viljamaa, S., Hodek, O., Moritz, Thomas & Niittylä, T., 2022, In: Plant Journal. 110, 5, p. 1493-1497

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

    Wang, Z., Emmerich, A., Pillon, N. J., Moore, T., Hemerich, D., Cornelis, M. C., Mazzaferro, E., Broos, S., Ahluwalia, T. S., Bartz, T. M., Bentley, A. R., Bielak, L. F., Chong, M., Chu, A. Y., Berry, D., Dorajoo, R., Dueker, N. D., Kasbohm, E., Feenstra, B., Feitosa, M. F. & 32 others, Gieger, C., Graff, M., Hall, L. M., Haller, T., Hartwig, F. P., Hillis, D. A., Huikari, V., Heard-Costa, N., Holzapfel, C., Jackson, A. U., Johansson, A., Jorgensen, A. M., Kaakinen, M. A., Karlsson, R., Kerr, K. F., Kim, B., Koolhaas, C. M., Kutalik, Z., Pacolet, A., Zhao, J., Balslev-Harder, M. N., Grarup, Niels, Linneberg, Allan René, Hansen, Torben, Melbye, M., Pedersen, Oluf Borbye, Pers, Tune H, Sørensen, Thorkild I.A., Zierath, Juleen R, Kilpeläinen, Tuomas O., Loos, Ruth & LifeLines Cohort Study, L. C. S., 2022, In: Nature Genetics. 54, p. 1332–1344 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    The Value of Rare Genetic Variation in the Prediction of Common Obesity in European Ancestry Populations

    Wang, Z., Choi, S. W., Chami, N., Boerwinkle, E., Fornage, M., Redline, S., Bis, J. C., Brody, J. A., Psaty, B. M., Kim, W., McDonald, M. L. N., Regan, E. A., Silverman, E. K., Liu, C. T., Vasan, R. S., Kalyani, R. R., Mathias, R. A., Yanek, L. R., Arnett, D. K., Justice, A. E. & 21 others, North, K. E., Kaplan, R., Heckbert, S., de Andrade, M., Guo, X., Lange, L. A., Rich, S., Rotter, J. I., Ellinor, P. T., Lubitz, S. A., Blangero, J., Shoemaker, M. B., Darbar, D., Gladwin, M. T., Albert, C. M., Chasman, D. I., Jackson, R. D., Kooperberg, C., Reiner, A. P., O’Reilly, P. F. & Loos, Ruth, 2022, In: Frontiers in Endocrinology. 13, 12 p., 863893.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Effects of carbohydrate restriction on body weight and glycemic control in individuals with type 2 diabetes: A randomized controlled trial of efficacy in real-life settings

    Weber, P., Thomsen, M. N., fbg982, fbg982, Samkani, A., Carl, M. H., Astrup, A., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Madsbad, Sten, Magkos, Faidon, Krarup, T. & Haugaard, Steen Bendix, 2022, In: Nutrients. 14, 24, 12 p., 5244.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation

    Wei, T-T., Chandy, M., Nishiga, M., Zhang, A., Kumar, K. K., Thomas, D., Manhas, A., Rhee, S., Justesen, J. M., Chen, I. Y., Wo, H-T., Khanamiri, S., Yang, J. Y., Seidl, F. J., Burns, N. Z., Liu, C., Sayed, N., Shie, J-J., Yeh, C-F., Yang, K-C. & 5 others, Lau, E., Lynch, K. L., Rivas, M., Kobilka, B. K. & Wu, J. C., 2022, In: Cell. 185, 10, p. 1676-1693.e23

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study

    Wesolowska-Andersen, A., Brorsson, C. A., Bizzotto, R., Mari, A., Tura, A., Koivula, R., Mahajan, A., Vinuela, A., Tajes, J. F., Sharma, S., Haid, M., Prehn, C., Artati, A., Hong, M. G., Musholt, P. B., Kurbasic, A., Masi, F. D., Tsirigos, K., Pedersen, H. K., Gudmundsdottir, V. & 31 others, Thomas, Cecilia Engel, Banasik, Karina, Jennison, C., Jones, A., Kennedy, G., Bell, J., Thomas, L., Frost, G., Thomsen, H., Allin, K., Hansen, T. H., drb459, drb459, Hansen, Torben, Rutters, F., Elders, P., t'Hart, L., Bonnefond, A., Canouil, M., Brage, S., Kokkola, T., Heggie, A., McEvoy, D., Hattersley, A., McDonald, T., Teare, H., Ridderstrale, M., Walker, M., Forgie, I., Pedersen, Oluf Borbye, Brunak, Søren & IMI-DIRECT consortium, I. C., 2022, In: Cell Reports Medicine. 3, 1, 25 p., 100477.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Acute effects on glucose tolerance by neprilysin inhibition in patients with type 2 diabetes

    Albrechtsen, Nicolai Jacob Wewer, Møller, A., Martinussen, C., Gluud, Lise Lotte, Rashu, E. B., Richter, Michael Martin, Plomgaard, Peter Stendahl, Goetze, Jens P. , Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2022, In: Diabetes, Obesity and Metabolism. 24, 10, p. 2017-2026 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    On measurements of glucagon secretion in healthy, obese, and Roux-en-Y gastric bypass operated individuals using sandwich ELISA

    Albrechtsen, Nicolai Jacob Wewer, Kjeldsen, Sasha Alexandra Sampson, Jensen, N. J., Rungby, Jørgen, Veedfald, Simon, Bojsen-Møller, K. N., Dirksen, C., Jensen, Christian Zinck, Martinussen, C., Madsbad, Sten & Holst, Jens Juul, 2022, In: Scandinavian Journal of Clinical & Laboratory Investigation. 82, 1, p. 75-83

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program

    Wheeler, M. M., Stilp, A. M., Rao, S., Halldórsson, B. V., Beyter, D., Wen, J., Mihkaylova, A. V., McHugh, C. P., Lane, J., Jiang, M. Z., Raffield, L. M., Jun, G., Sedlazeck, F. J., Metcalf, G., Yao, Y., Bis, J. B., Chami, N., de Vries, P. S., Desai, P., Floyd, J. S. & 39 others, Gao, Y., Kammers, K., Kim, W., Moon, J. Y., Ratan, A., Yanek, L. R., Almasy, L., Becker, L. C., Blangero, J., Cho, M. H., Curran, J. E., Fornage, M., Kaplan, R. C., Lewis, J. P., Loos, Ruth, Mitchell, B. D., Morrison, A. C., Preuss, M., Psaty, B. M., Rich, S. S., Rotter, J. I., Tang, H., Tracy, R. P., Boerwinkle, E., Abecasis, G. R., Blackwell, T. W., Smith, A. V., Johnson, A. D., Mathias, R. A., Nickerson, D. A., Conomos, M. P., Li, Y., Þorsteinsdóttir, U., Magnússon, M. K., Stefansson, K., Pankratz, N. D., Bauer, D. E., Auer, P. L. & Reiner, A. P., 2022, In: Nature Communications. 13, 18 p., 7592.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

    Winkler, T. W., Rasheed, H., Teumer, A., Gorski, M., Rowan, B. X., Stanzick, K. J., Thomas, L. F., Tin, A., Hoppmann, A., Chu, A. Y., Tayo, B., Thio, C. H. L., Cusi, D., Chai, J-F., Sieber, K. B., Horn, K., Li, M., Scholz, M., Cocca, M., Wuttke, M. & 31 others, van der Most, P. J., Yang, Q., Ghasemi, S., Nutile, T., Li, Y., Pontali, G., Günther, F., Dehghan, A., Correa, A., Parsa, A., Feresin, A., de Vries, A. P. J., Zonderman, A. B., Smith, A. V., Oldehinkel, A. J., De Grandi, A., Rosenkranz, A. R., Franke, A., Teren, A., Metspalu, A., Hicks, A. A., Morris, A. P., Tönjes, A., Morgan, A., Podgornaia, A. I., Christensen, K., Lind, L., Kovacs, P., Rossing, Peter, Loos, Ruth & LifeLines Cohort Study, L. C. S., 2022, In: Communications Biology . 5, p. 580 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Fueling the fire of adipose thermogenesis

    Wolfrum, C. & Gerhart-Hines, Zach, 2022, In: Science. 375, 6586, p. 1229-1231 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers

    Xu, R., Höß, C., Swiercz, J. M., Brandt, D. T., Lutz, V., Petersen, N., Li, R., Zhao, D., Oleksy, A., Creigh-Pulatmen, T., Trokter, M., Fedorova, M., Atzberger, A., Strandby, R. B., Olsen, A. A., Achiam, M. P., Matthews, D., Huber, M., Gröne, H-J., Offermanns, S. & 1 others, Worzfeld, T., 2022, In: Science Translational Medicine. 14, 654, eabf1922.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    A saturated map of common genetic variants associated with human height

    Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y. & 37 others, Karaderi, Tugce, Lin, K., Lull, K., Malden, D. E., Lepola, Mette Andersen, Appadurai, V., Bork-Jensen, J., Burgdorf, Kristoffer Sølvsten, Hansen, Thomas Folkmann, Jonsson, Anna Elisabet, Jorgensen, T., Liu, J., Møllehave, Line Tang, Smit, Roelof Adriaan Johan, Zhao, J., Bisgaard, H., Bønnelykke, Klaus, Dantoft, T. M., Grarup, Niels, Hansen, Torben, Jackson, R. D., Karpe, F., Kovacs, P., Lind, L., Linneberg, Allan René, Pedersen, Oluf Borbye, Werge, Thomas, Sun, Y., Loos, Ruth, Winkler, T. W., 23andMe Res Team, 2. R. T., VA Million Vet Program, V. M. V. P., DiscovEHR DiscovEHR MyCode Communi, D. D. M. C., eEMERGE Elect Med Records Genomics, E. E. M. R. G., LifeLines Cohort Study, L. C. S., PRACTICAL consortium, P. C. & Understanding Soc Sci Grp, U. S. S. G., 2022, In: Nature. 610, p. 704–712

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

    Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J-W., Haessler, J., Lyytikäinen, L-P., Repetto, L., Concas, M. P., van den Berg, M. E., Weiss, S., Baldassari, A. R., Bartz, T. M., Cook, J. P., Evans, D. S. & 31 others, Freudling, R., Hines, O., Isaksen, Jonas L., Lin, H., Mei, H., Moscati, A., Müller-Nurasyid, M., Nursyifa, Casia, Qian, Y., Richmond, A., Roselli, C., Ryan, K. A., Tarazona-Santos, E., Thériault, S., van Duijvenboden, S., Warren, H. R., Yao, J., Raza, D., Aeschbacher, S., Ahlberg, Gustav, Andreasen, Laura Korsholm, Ellervik, Christina, Hansen, Torben, Jackson, R. D., Lind, L., Linneberg, Allan René, Grarup, Niels, Kanters, Jørgen K., Loos, Ruth, Olesen, Morten Steen Salling & CHARGE Consortium, C. C., 2022, In: Nature Communications. 13, 1, 18 p., 5144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease

    Zhou, W., Kanai, M., Wu, K. H. H., Rasheed, H., Tsuo, K., Hirbo, J. B., Wang, Y., Bhattacharya, A., Zhao, H., Namba, S., Surakka, I., Wolford, B. N., Lo Faro, V., Lopera-Maya, E. A., Läll, K., Favé, M. J., Partanen, J. J., Chapman, S. B., Karjalainen, J., Kurki, M. & 54 others, Maasha, M., Brumpton, B. M., Chavan, S., Chen, T. T., Daya, M., Ding, Y., Feng, Y. C. A., Guare, L. A., Gignoux, C. R., Graham, S. E., Hornsby, W. E., Ingold, N., Ismail, S. I., Johnson, R., Laisk, T., Lin, K., Lv, J., Millwood, I. Y., Moreno-Grau, S., Nam, K., Palta, P., Pandit, A., Preuss, M. H., Saad, C., Setia-Verma, S., Thorsteinsdottir, U., Uzunovic, J., Verma, A., Zawistowski, M., Loos, Ruth, deCODE Genetics, D. G., Estonian Biobank, E. B., FinnGen, F., Generation Scotland, G. S., Genes & Health Research Team, G. &. H. R. T., LifeLines, L., Mass General Brigham Biobank, M. G. B. B., Michigan Genomics Initiative, M. G. I., National Biobank of Korea, N. B. O. K., Penn Medicine BioBank, P. M. B., Qatar Biobank, Q. B., The QSkin Sun and Health Study, T. Q. S. A. H. S., Taiwan Biobank, T. B., The HUNT Study, T. H. S., UCLA ATLAS Community Health Initiative, U. A. C. H. I., Uganda Genome Resource, U. G. R., UK Biobank, U. B., Biobank of the Americas, B. O. T. A., BioBank Japan Project, B. J. P., BioMe, B., BioVU, B., CanPath - Ontario Health Study, C. -. O. H. S., China Kadoorie Biobank Collaborative Group, C. K. B. C. G. & Colorado Center for Personalized Medicine, C. C. F. P. M., 2022, In: Cell Genomics. 2, 10, 20 p., 100192.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Ellagic Acid prevents vascular dysfunction in small mesenteric arteries of ovariectomized hypertensive rats

    da Silva, F. B., Romero, W. G., Rouver, W. D. N., Silva, K., de Almeida, S. A., Mengal, V., Peluso, A. A., Endlich, P. W., Bissoli, N. S., Claudio, E. R. G. & de Abreu, G. R., 2022, In: Journal of Nutritional Biochemistry. 105, 8 p., 108995.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    High-Throughput UHPLC-MS to Screen Metabolites in Feces for Gut Metabolic Health

    de Zawadzki, A., Thiele, M., Suvitaival, T., Wretlind, A., Kim, M., Ali, M., Bjerre, A. F., Stahr, K., Mattila, I., Hansen, Torben, Krag, A. & Legido-Quigley, C., 2022, In: Metabolites. 12, 3, 16 p., 211.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    The effects of laparoscopic Roux-en-Y gastric bypass and one-anastomosis gastric bypass on glycemic control and remission of type 2 diabetes mellitus: study protocol for a multi-center randomized controlled trial (the DIABAR-trial)

    van Rijswijk, A., van Olst, N., Meijnikman, A. S., Acherman, Y. I. Z., Bruin, S. C., van de Laar, A. W., van Olden, C. C., Aydin, O., Borger, H., Beuers, U. H. W., Herrema, H., Verheij, J., Apers, J. A., Bäckhed, F., Gerdes, V. E. A., Nieuwdorp, M. & de Brauw, L. M., 2022, In: Trials. 23, 12 p., 900.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Molecular and in vivo phenotyping of missense variants of the human glucagon receptor

    van der Velden, W. J. C., Lindquist, Peter, Madsen, Jakob Sture, Stassen, R. H. M. J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, M. M., 2022, In: Journal of Biological Chemistry. 298, 2, 101413.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Endurance training improves GLP-1 sensitivity and glucose tolerance in overweight women

    Åkerström, T., Stolpe, Malene Norup, Widmer, R., Dejgaard, T. F., Højberg, J. M., Møller, Kirsten, Hansen, J. S., Trinh, B., Holst, Jens Juul, Thomsen, C., Pedersen, Bente Klarlund & Ellingsgaard, H., 2022, In: Journal of the Endocrine Society. 6, 9, p. 1-8 8 p., bvac111.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. 2021
  81. Published

    Birthweight, Childhood Body Mass Index, Height and Growth, and Risk of Polycystic Ovary Syndrome

    Aarestrup, J., Pedersen, D. C., Thomas, P. E., Glintborg, D., Holm, Jens-Christian, Bjerregaard, L. G. & Baker, J. L., 2021, In: Obesity Facts. 14, 3, p. 283-290 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Genetic markers of abdominal obesity and weight loss after gastric bypass surgery

    Aasbrenn, M., Svendstrup, M., Schnurr, T. M., Hansen, D. L., Worm, Dorte, Balslev-Harder, M., Grarup, Niels, Burgdorf, Kristoffer Sølvsten, drb459, drb459, Pedersen, Oluf Borbye, Ängquist, Lars, Fenger, M., Sørensen, Thorkild I.A., Madsbad, Sten & Hansen, Torben, 2021, In: PLoS ONE. 16, 5, 11 p., 0252525.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    A diet-induced gut microbiota component and related plasma metabolites are associated with depressive-like behaviour in rats

    Abildgaard, A., Kern, T., Pedersen, Oluf Borbye, Hansen, Torben, Lund, S. & Wegener, G., 2021, In: European Neuropsychopharmacology. 43, p. 10-21

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Preserved postprandial suppression of bone turnover markers, despite increased fasting levels, in postmenopausal women

    Abildgaard, J., Ploug, Thorkil, Pedersen, Anette Tønnes, Eiken, P., Pedersen, Bente Klarlund, Holst, Jens Juul, Hartmann, Bolette & Lindegaard, Birgitte, 2021, In: Bone. 143, 8 p., 115612.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci

    Ahluwalia, T. S., Prins, B. P., Abdollahi, M., Armstrong, N. J., Aslibekyan, S., Bain, L., Jefferis, B., Baumert, J., Beekman, M., Ben-Shlomo, Y., Bis, J. C., Mitchell, B. D., de Geus, E., Delgado, G. E., Marek, D., Eriksson, J., Kajantie, E., Kanoni, S., Kemp, J. P., Lu, C. & 31 others, Marioni, R. E., McLachlan, S., Milaneschi, Y., Nolte, I. M., Petrelis, A. M., Porcu, E., Sabater-Lleal, M., Naderi, E., Seppälä, I., Shah, T., Singhal, G., Standl, M., Teumer, A., Thalamuthu, A., Thiering, E., Trompet, S., Ballantyne, C. M., Benjamin, E. J., Casas, J. P., Toben, C., Dedoussis, G., Deelen, J., Durda, P., Engmann, J., Feitosa, M. F., Grallert, H., Hammarstedt, A., Jess, T., Rossing, Peter, Sørensen, Thorkild I.A. & CHARGE Inflammation Working Group, C. I. W. G., 2021, In: Human Molecular Genetics. 30, 5, p. 393–409

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Transcriptomics analysis of differentially expressed genes in subcutaneous and perirenal adipose tissue of sheep as affected by their pre- and early postnatal malnutrition histories

    Ahmad, S., Drag, Markus Hodal, Salleh, S. M., Cai, Z. & Nielsen, M. O., 2021, In: BMC Genomics. 22, 1, 21 p., 338.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965

    Ahwazi, Danial, Neopane, K., Markby, G. R., Kopietz, F., Ovens, A. J., Dall, M., Hassing, Anna Skab, Gräsle, P., Alshuweishi, Y., Treebak, Jonas Thue, Salt, I. P., Göransson, O., Zeqiraj, E., Scott, J. W. & Sakamoto, Kei, 2021, In: Biochemical Journal. 478, 15, p. 2977-2997 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Fat-Secreted Ceramides Regulate Vascular Redox State and Influence Outcomes in Patients With Cardiovascular Disease

    Akawi, N., Checa, A., Antonopoulos, A. S., Akoumianakis, I., Daskalaki, E., Kotanidis, C. P., Kondo, H., Lee, K., Yesilyurt, D., Badi, I., Polkinghorne, M., Akbar, N., Lundgren, J., Chuaiphichai, S., Choudhury, R., Neubauer, S., Channon, K. M., Torekov, Signe Sørensen, Wheelock, C. E. & Antoniades, C., 2021, In: American College of Cardiology. Symposia. 77, 20, p. 2494-2513

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Bariatric Surgery and Risk of New-onset Inflammatory Bowel Disease: A Nationwide Cohort Study

    Allin, K. H., Jacobsen, R. K., Ungaro, R. C., Colombel, J. F., Egeberg, A., Villumsen, M. & Jess, T., 2021, In: Journal of Crohn's and Colitis. 15, 9, p. 1474-1480 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Perinatal exposure to nicotine alters spermatozoal DNA methylation near genes controlling nicotine action

    Altıntaş, Ali, Liu, J., Fabre, O., Chuang, T., Wang, Y., Sakurai, R., Chehabi, G. N., Barrès, Romain & Rehan, V. K., 2021, In: F A S E B Journal. 35, 7, e21702.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Trans-ethnic gut microbiota signatures of type 2 diabetes in Denmark and India

    Alvarez-Silva, C., Kashani, A., Hansen, T. H., Pinna, N. K., Anjana, R. M., Dutta, A., Saxena, S., Støy, J., Kampmann, U., Nielsen, T., Jørgensen, T., Gnanaprakash, V., Gnanavadivel, R., Sukumaran, A., Rani, C. S. S., Færch, K., Radha, V., Balasubramanyam, M., Nair, G. B., Das, B. & 6 others, drb459, drb459, Hansen, Torben, Mande, S. S., Mohan, V., Arumugam, Mani & Pedersen, Oluf Borbye, 2021, In: Genome Medicine. 13, 37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Effects of a self-prepared carbohydrate-reduced high-protein diet on cardiovascular disease risk markers in patients with type 2 diabetes

    Alzahrani, A. H., Skytte, M. J., Samkani, A., Thomsen, M. N., Astrup, A., Ritz, C., Frystyk, J., Holst, Jens Juul, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T., Larsen, T. M. & Magkos, Faidon, 2021, In: Nutrients. 13, 5, 10 p., 1694.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Body weight and metabolic risk factors in patients with type 2 diabetes on a self-selected high-protein low-carbohydrate diet

    Alzahrani, A. H. A., Skytte, M. J., Samkani, A., Thomsen, M. N., Astrup, A., Ritz, C., Chabanova, E., Frystyk, J., Holst, Jens Juul, Thomsen, Henrik S., Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T., Larsen, T. M. & Magkos, Faidon, 2021, In: European Journal of Nutrition. 60, 8, p. 4473-4482 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Associations of hypoglycaemia and glycaemic variability with cardiac arrhythmias using a long-term monitoring approach in insulin-treated patients with type 2 diabetes

    Andersen, A., Bagger, J. I., Sorensen, S. K., Baldassarre, M. P. A., Pedersen-Bjergaard, Ulrik, Forman, Julie Lyng, Gislason, Gunnar Hilmar, Lindhardt, T. B., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetologia. 64, SUPPL 1, p. 135-135 257.

    Research output: Contribution to journalConference abstract in journalResearch

  95. Published

    A Pharmacological and Clinical Overview of Oral Semaglutide for the Treatment of Type 2 Diabetes

    Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Drugs. 81, p. 1003-1030 28 p.

    Research output: Contribution to journalReviewResearchpeer-review

  96. Published

    Acute hypoglycemia and risk of cardiac arrhythmias in insulin-treated type 2 diabetes and controls

    Andersen, A., Bagger, J. I., Baldassarre, M. P., Christensen, Mikkel Bring, Abelin, K. U., Faber, Jens, Pedersen-Bjerregaard, U., Holst, Jens Juul, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: European Journal of Endocrinology. 185, 2, p. 343-353 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Associations of hypoglycemia, glycemic variability and risk of cardiac arrhythmias in insulin-treated patients with type 2 diabetes: a prospective, observational study

    Andersen, A., Bagger, J. I., Sørensen, S. K., Baldassarre, M. P. A., Pedersen-Bjergaard, Ulrik, Forman, Julie Lyng, Gislason, Gunnar Hilmar, Lindhardt, T. B., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Cardiovascular Diabetology. 20, 1, 10 p., 241.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Using a Reporter Mouse to Map Known and Novel Sites of GLP-1 Receptor Expression in Peripheral Tissues of Male Mice

    Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Pedersen, Jens, Kuhre, Rune Ehrenreich, Lund, M. L., Holst, Jens Juul & Ørskov, Cathrine, 2021, In: Endocrinology. 162, 3, bqaa246.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Maternal thyroid disease and adiposity in mother and child

    Andersen, S. L., Andersen, S., Liew, Z., Vestergaard, P., Lundbye-Christensen, S., Sørensen, Thorkild I.A. & Olsen, J., 2021, In: Clinical Endocrinology. 94, 3, p. 484-493 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Ocular Surface Microbiota in Contact Lens Users and Contact-Lens-Associated Bacterial Keratitis

    Andersson, J., Vogt, J. K., Dalgaard, M. D., Pedersen, Oluf Borbye, Holmgaard, Kim & Heegaard, Steffen, 2021, In: Vision (Switzerland). 5, 2, 12 p., 27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Ocular surface microbiota in patients with aqueous tear-deficient dry eye

    Andersson, J., Vogt, J. K., Dalgaard, M. D., Pedersen, Oluf Borbye, Holmgaard, Kim & Heegaard, Steffen, 2021, In: Ocular Surface. 19, p. 210-217

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

    Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., González, M. J., Gil Flores, S., Cabaleiro Fabeiro, F. J., del Río Noriega, F., Perez, F. P., Haro González, J., Orozco Diaz, G., de Diego-Otero, Y., Moreno-Küstner, B., Auburger, G., Degenhardt, F., Heilmann-Heimbach, S., Herms, S., Hoffmann, P., Frank, J., Foo, J. C. & 26 others, Treutlein, J., Witt, S. H., Cichon, S., Kogevinas, M., Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R. I., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pers, Tune H, Bækvad-Hansen, M., Pedersen, C. B., Pedersen, M. G., Hansen, C. S., Nordentoft, Merete, Werge, Thomas, Hansen, Thomas Folkmann, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, B. D. W. G. O. T. P. G. C. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2021, In: Molecular Psychiatry. 26, 4, p. 1286-1298 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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