Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2023
  2. Published

    Role of sociodemographic, clinical, behavioral, and molecular factors in precision prevention of type 2 diabetes: a systematic review

    Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD Precision Medicine in Diabetes Initiative, A. P. M. I. D. I., 2023, medRxiv.

    Research output: Working paper › Preprint › Research

  3. Published

    Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

    Maury, E. A., Sherman, M. A., Genovese, G., Gilgenast, T. G., Kamath, T., Burris, S. J., Rajarajan, P., Flaherty, E., Akbarian, S., Chess, A., McCarroll, S. A., Loh, P. R., Phillips-Cremins, J. E., Brennand, K. J., Macosko, E. Z., Walters, J. T. R., O'Donovan, M., Sullivan, P., Werge, T., Pers, T. H. & 2 others, Brain Somatic Mosaicism Network, B. S. M. N. & Psychiatric Genomic Consortium Schizophrenia and CNV workgroup, P. G. C. S. A. C. W., 2023, In: Cell Genomics. 3, 8, 22 p., 100356.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Seasonal light hours modulate peripheral clocks and energy metabolism in mice

    Small, Lewin Barkla, Lundell, L. S., Iversen, Jo Frøkjær, Ehrlich, Amy M, Dall, M., Basse, A. L., Kellezi, Emilie Dalbram, Hansen, Ann Normann, Treebak, Jonas Thue, Barrès, Romain & Zierath, Juleen R, 2023, In: Cell Metabolism. 35, 10, p. 1722-1735.e5 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

    Tobias, D. K., Merino, J., Ahmad, A., Aiken, C., Benham, J. L., Bodhini, D., Clark, A. L., Colclough, K., Corcoy, R., Cromer, S. J., Duan, D., Felton, J. L., Francis, E. C., Gillard, P., Gingras, V., Gaillard, R., Haider, E., Hughes, A., Ikle, J. M., Jacobsen, L. M. & 180 others, Kahkoska, A. R., Kettunen, J. L. T., Kreienkamp, R. J., Lim, L. L., Männistö, J. M. E., Massey, R., Mclennan, N. M., Miller, R. G., Morieri, M. L., Most, J., Naylor, R. N., Ozkan, B., Patel, K. A., Pilla, S. J., Prystupa, K., Raghavan, S., Rooney, M. R., Schön, M., Semnani-Azad, Z., Sevilla-Gonzalez, M., Svalastoga, P., Takele, W. W., Tam, C. H. T., Thuesen, Anne Cathrine Baun, Tosur, M., Wallace, A. S., Wang, C. C., Wong, J. J., Yamamoto, J. M., Young, K., Amouyal, C., Lepola, Mette Andersen, Bonham, M. P., Chen, M., Cheng, F., Chikowore, T., Chivers, S. C., Clemmensen, Christoffer, Dabelea, D., Dawed, A. Y., Deutsch, A. J., Dickens, L. T., DiMeglio, L. A., Dudenhöffer-Pfeifer, M., Evans-Molina, C., Fernández-Balsells, M. M., Fitipaldi, H., Fitzpatrick, S. L., Gitelman, S. E., Goodarzi, M. O., Grieger, J. A., Guasch Ferre, Marta, Habibi, N., Hansen, Torben, Huang, C., Harris-Kawano, A., Ismail, H. M., Hoag, B., Johnson, R. K., Jones, A. G., Koivula, R. W., Leong, A., Leung, G. K. W., Libman, I. M., Liu, K., Long, S. A., Lowe, W. L., Morton, R. W., Motala, A. A., Onengut-Gumuscu, S., Pankow, J. S., Pathirana, M., Pazmino, S., Perez, D., Petrie, J. R., Powe, C. E., Quinteros, A., Jain, R., Ray, D., Ried-Larsen, M., Saeed, Z., Santhakumar, V., Kanbour, S., Sarkar, S., Monaco, G. S. F., Scholtens, D. M., Selvin, E., Sheu, W. H. H., Speake, C., Stanislawski, M. A., Steenackers, N., Steck, A. K., Stefan, N., Støy, J., Taylor, R., Tye, S. C., Ukke, G. G., Urazbayeva, M., Van der Schueren, B., Vatier, C., Wentworth, J. M., Hannah, W., White, S. L., Yu, G., Zhang, Y., Zhou, S. J., Beltrand, J., Polak, M., Aukrust, I., de Franco, E., Flanagan, S. E., Maloney, K. A., McGovern, A., Molnes, J., Nakabuye, Mariam, Njølstad, P. R., Pomares-Millan, H., Provenzano, M., Saint-Martin, C., Zhang, C., Zhu, Y., Auh, S., de Souza, R., Fawcett, A. J., Gruber, C., Mekonnen, E. G., Mixter, E., Sherifali, D., Eckel, R. H., Nolan, J. J., Philipson, L. H., Brown, R. J., Billings, L. K., Boyle, K., Costacou, T., Dennis, J. M., Florez, J. C., Gloyn, A. L., Gomez, M. F., Gottlieb, P. A., Greeley, S. A. W., Griffin, K., Hattersley, A. T., Hirsch, I. B., Hivert, M. F., Hood, K. K., Josefson, J. L., Kwak, S. H., Laffel, L. M., Lim, S. S., Loos, Ruth, Ma, R. C. W., Mathieu, C., Mathioudakis, N., Meigs, J. B., Misra, S., Mohan, V., Murphy, R., Oram, R., Owen, K. R., Ozanne, S. E., Pearson, E. R., Perng, W., Pollin, T. I., Pop-Busui, R., Pratley, R. E., Redman, L. M., Redondo, M. J., Reynolds, R. M., Semple, R. K., Sherr, J. L., Sims, E. K., Sweeting, A., Tuomi, T., Udler, M. S., Vesco, K. K., Vilsbøll, Tina, Wagner, R., Rich, S. S. & Franks, P. W., 2023, In: Nature Medicine. 29, 10, p. 2438-2457 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Secretion and Impact of Gut Hormones in Obesity and Diabetes

    Holst, Jens Juul, 2023, Encyclopedia of Cell Biology: Systems, Translational and Specialized Cell Aspects of Cell Biology. Bradshaw, R. A., Hart, G. W. & Stahl, P. D. (eds.). 2 ed. Elsevier, Vol. 6. p. 543-550 8 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  7. Published

    Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery

    Lappa, D., Meijnikman, A. S., Krautkramer, K. A., Olsson, L. M., Aydin, Ö., Van Rijswijk, A. S., Acherman, Y. I. Z., De Brauw, M. L., Tremaroli, V., Olofsson, L. E., Lundqvist, A., Hjorth, Siv Annegrethe, Ji, B., Gerdes, V. E. A., Groen, A. K., Schwartz, Thue W., Nieuwdorp, M., Bäckhed, F. & Nielsen, J., 2023, In: PLoS ONE. 18, 3, 26 p., e0279335.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Serotonin receptor 4 agonism prevents high fat diet induced reduction in GLP-1 in mice

    Vanslette, A. M., Toft, P. B., Lund, M. L., Moritz, Thomas & Arora, Tulika, 2023, In: European Journal of Pharmacology. 960, 176181.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Sex differences in muscle protein expression and DNA methylation in response to exercise training

    Landen, S., Jacques, M., Hiam, D., Alvarez-Romero, J., Schittenhelm, R. B., Shah, A. D., Huang, C., Steele, J. R., Harvey, N. R., Haupt, L. M., Griffiths, L. R., Ashton, K. J., Lamon, S., Voisin, S. & Eynon, N., 2023, In: Biology of Sex Differences. 14, 20 p., 56.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Sleep-Time eating boosts exercise endurance

    Treebak, Jonas Thue, 2023, In: Life Metabolism. 2, 5, 2 p., load029.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Sphingolipids Are Depleted in Alcohol-Related Liver Fibrosis

    Thiele, M., Suvitaival, T., Trošt, K., Kim, M., de Zawadzki, A., Kjaergaard, M., Rasmussen, D. N., Lindvig, K. P., Israelsen, M., Detlefsen, S., Andersen, P., Juel, H. B., Nielsen, T., Georgiou, S., Filippa, V., Kuhn, M., Nishijima, S., Moitinho-Silva, L., Rossing, P., Trebicka, J. & 14 others, Anastasiadou, E., Bork, P., Hansen, T., Legido-Quigley, C., Krag, A., Mann, M., Matthijnssens, J., Arumugam, Mani, Henrar, R., Israelsen, H., Karsdal, M., Melberg, H. O., MicrobLiver Consortium, M. C. & GALAXY Consortium, G. C., 2023, In: Gastroenterology. 164, 7, p. 1248-1260

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones

    Pedersen, K., Andersen, H., Fledelius, C., Holst, Jens Juul, Hjuler, S. T. & Kuhre, Rune Ehrenreich, 2023, In: Molecular Metabolism. 69, 101689.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease

    Gupta, Y., Friedman, D. J., McNulty, M. T., Khan, A., Lane, B., Wang, C., Ke, J., Jin, G., Wooden, B., Knob, A. L., Lim, T. Y., Appel, G. B., Huggins, K., Liu, L., Mitrotti, A., Stangl, M. C., Bomback, A., Westland, R., Bodria, M., Marasa, M. & 60 others, Shang, N., Cohen, D. J., Crew, R. J., Morello, W., Canetta, P., Radhakrishnan, J., Martino, J., Liu, Q., Chung, W. K., Espinoza, A., Luo, Y., Wei, W., Feng, Q., Weng, C., Fang, Y., Kullo, I. J., Naderian, M., Limdi, N., Irvin, M. R., Tiwari, H., Mohan, S., Rao, M., Dube, G. K., Chaudhary, N. S., Gutiérrez, O. M., Judd, S. E., Cushman, M., Lange, L. A., Lange, E. M., Bivona, D. L., Verbitsky, M., Winkler, C. A., Kopp, J. B., Santoriello, D., Batal, I., Pinheiro, S. V. B., Oliveira, E. A., Simoes e Silva, A. C., Pisani, I., Fiaccadori, E., Lin, F., Gesualdo, L., Amoroso, A., Ghiggeri, G. M., D’Agati, V. D., Magistroni, R., Kenny, E. E., Loos, Ruth, Montini, G., Hildebrandt, F., Paul, D. S., Petrovski, S., Goldstein, D. B., Kretzler, M., Gbadegesin, R., Gharavi, A. G., Kiryluk, K., Sampson, M. G., Pollak, M. R. & Sanna-Cherchi, S., 2023, In: Nature Communications. 14, 8 p., 7836.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Structural elucidation of 3-nitrophenylhydrazine derivatives of tricarboxylic acid cycle acids and optimization of their fragmentation to boost sensitivity in liquid chromatography-mass spectrometry

    Hodek, O., Henderson, John David, Argemi Muntadas, Lidia, Khan, Adnan & Moritz, Thomas, 2023, In: Journal of Chromatography - B. 1222, 9 p., 123719.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Sugar- or artificially-sweetened beverage consumption, physical activity, and risk of cardiovascular disease in US adults

    Pacheco, L. S., Tobias, D. K., Li, Y., Bhupathiraju, S. N., Willett, W. C., Ludwig, D. S., Ebbeling, C. B., Haslam, D. E., Drouin-Chartier, J., Hu, F. B. & Guasch Ferre, Marta, 2023, medRxiv, 29 p.

    Research output: Working paper › Preprint › Research

  16. Published

    Supplementation of cyanidin-3-O-β-glucoside-rich haskap (Lonicera caerulea L.) berry extract attenuates hepatic lipid dysregulation in diet-induced obese mice

    Biswas, Dipsikha, De Silva, A. B. K. H., Mercer, A., Sarkar, S., Kienesberger, P., Langille, M., Rupasinghe, H. P. V. & Pulinilkunnil, T., 2023, In: Journal of Functional Foods. 108, 11 p., 105635.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Synergy and oxygen adaptation for development of next-generation probiotics

    Khan, M. T., Dwibedi, C., Sundh, D., Pradhan, M., Kraft, J. D., Caesar, R., Tremaroli, V., Lorentzon, M. & Bäckhed, F., 2023, In: Nature. 620, p. 381-385

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    TBC1D4-S711 controls skeletal muscle insulin sensitization after exercise and contraction

    Kjøbsted, Rasmus, Kristensen, Jonas Møller, Eskesen, N. O., Kido, K., Fjorder, Klara, Damgaard, D. F., Larsen, Jeppe Kjærgaard, Andersen, Nicoline Resen, Birk, Jesper Bratz, Gudiksen, Anders, Treebak, Jonas Thue, Schjerling, Peter, Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2023, In: Diabetes. 72, 7, p. 857-871 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    TNIK is a conserved regulator of glucose and lipid metabolism in obesity

    Pham, Tang Cam Phung, Dollet, L., Ali, Mona Sadek, Raun, Steffen Henning, Møller, Lisbeth L V, Jafari Kermani, Abbas, Ditzel, N., Andersen, Nicoline Resen, Fritzen, Andreas Mæchel, Gerhart-Hines, Zach, Kiens, Bente, Suomalainen, A., Simpson, S. J., Salling Olsen, M., Kieser, A., Schjerling, Peter, Nieminen, A. I., Richter, Erik A., Havula, E. & Sylow, Lykke, 2023, In: Science Advances. 9, 32, 18 p., eadf7119.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Targeted Analysis of Phosphorylated Metabolites in Biological Samples by HILIC–LC–MS

    Hodek, O., Jiang, W. & Moritz, Thomas, 2023, In: LC-GC North America. 41, 8, p. 354-355 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  21. Published

    Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice

    Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Sørensen, C., Størling, Joachim, Moritz, Thomas, Mariño, E. & Billestrup, Nils, 2023, In: International Journal of Molecular Sciences. 24, 5, 17 p., 4533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα

    Griem-Krey, Nane, Klein, A. B., Clausen, B. H., Namini, M. R. J., Nielsen, P. V., Bhuiyan, M., Nagaraja, R. Y., De Silva, T. M., Sobey, C. G., Cheng, H. C., Orset, C., Vivien, D., Lambertsen, K. L., Clarkson, A. N. & Wellendorph, Petrine, 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 8, p. 1419-1434

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The Prevalence of Polyneuropathy in Type 2 Diabetes Subgroups Based on HOMA2 Indices of β-Cell Function and Insulin Sensitivity

    Kristensen, F. P. B., Christensen, D. H., Callaghan, B. C., Stidsen, J. V., Nielsen, J. S., Højlund, K., Beck-Nielsen, H., Jensen, T. S., Andersen, H., Vestergaard, P., Jessen, N., Olsen, M. H., Hansen, Torben, Brøns, C., Vaag, Allan, Sørensen, H. T. & Thomsen, R. W., 2023, In: Diabetes Care. 46, 8, p. 1546-1555 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions

    Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, Clemmensen, Christoffer, 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The biochemistry and physiology of long-chain dicarboxylic acid metabolism

    Ranea-Robles, Pablo & Houten, S. M., 2023, In: Biochemical Journal. 480, 9, p. 607-627 21 p.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    The contribution of functional HNF1A variants and polygenic susceptibility to risk of type 2 diabetes in ancestrally diverse populations

    Stalbow, L. A., Preuss, M. H., Smit, Roelof Adriaan Johan, Chami, N., Bjørkhaug, L., Aukrust, I., Gloyn, A. L. & Loos, Ruth, 2023, In: Diabetologia. 66, p. 116-126 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The dietary regulation of LEAP2 depends on meal composition in mice

    Gradel, Anna Katrina Jógvansdóttir, Holm, Stephanie Kjærulff, Byberg, Sarah, Merkestein, M., Hogendorf, W. F. J., Lund, M. L., Buijink, Jesse A., Damgaard, J., Lykkesfeldt, Jens & Holst, Birgitte, 2023, In: FASEB Journal. 37, 6, 21 p., 22923.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The effect of diabetes and the diabetogenic TBC1D4 p.Arg684ter variant on kidney function in Inuit in Greenland

    Overvad, M., Díaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Grarup, Niels, Hansen, Torben, Rossing, Peter & Jørgensen, M. E., 2023, In: International Journal of Circumpolar Health. 82, 8 p., 2191406.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The effect of ferritin-guided iron supplementation among Danish female first-time blood donors

    Drechsler, L. Ø., Boldsen, J. K., Hindhede, L., Aagaard, B., Harritshøj, Lene Holm, Mikkelsen, Christina, Brodersen, T., Brøns, N., Schwinn, M., Hjalgrim, Henrik, Rostgaard, K., Topholm Bruun, M., Ostrowski, Sisse Rye, Pedersen, Ole Birger Vesterager, Mikkelsen, S. & Erikstrup, C., 2023, In: Transfusion. 63, 9, p. 1710-1718 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    The effect of sucrase-isomaltase deficiency on metabolism, food intake and preferences: protocol for a dietary intervention study

    Senftleber, N. K., Pedersen, K. S., Schnoor Jørgensen, C., Pedersen, H., Bjerg Christensen, M. M., Kabel Madsen, E., Andersen, K., Jørsboe, E., Gillum, M. P., Frøst, Michael Bom, Hansen, Torben & Jørgensen, M. E., 2023, In: International Journal of Circumpolar Health. 82, 1, 10 p., 2178067.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The effect of traditional diet on glucose homeostasis in carriers and non-carriers of a common TBC1D4 variant in Greenlandic Inuit: A randomized crossover study

    Lewis, Jack Ivor, Lind, M. V., Møller, G., Hansen, Torben, Pedersen, H., Christensen, M. M. B., Laursen, J. C., Nielsen, S., Ottendahl, C. B., Larsen, C. V. L., Stark, K. D., Bjerregaard, P., Jørgensen, M. E. & Lauritzen, Lotte, 2023, In: British Journal of Nutrition. 130, 11, p. 1871-1884

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The expanding incretin universe: from basic biology to clinical translation

    Drucker, D. J. & Holst, Jens Juul, 2023, In: Diabetologia. 66, p. 1765-1779

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice

    Fan, Y., Støving, R. K., Berreira Ibraim, S., Hyötyläinen, T., Thirion, F., Arora, T., Lyu, L., Stankevic, E., Hansen, T. H., Déchelotte, P., Sinioja, T., Ragnarsdottir, O., Pons, N., Galleron, N., Quinquis, B., Levenez, F., Roume, H., Falony, G., Vieira-Silva, S., Raes, J. & 6 others, Clausen, L., Telléus, G. K., Bäckhed, F., Oresic, M., Ehrlich, S. D. & Pedersen, Oluf Borbye, 2023, In: Nature Microbiology. 8, p. 787–802

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The gut microbiota in multiple sclerosis varies with disease activity

    Thirion, F., Sellebjerg, Finn Thorup, Fan, Yong, Lyu, Liwei, Hansen, T. H., Pons, N., Levenez, F., Quinquis, B., Stankevic, Evelina, Søndergaard, H. B., Dantoft, T. M., Poulsen, C. S., Forslund, S. K., drb459, drb459, Hansen, Torben, Brix, S., Oturai, A., Sørensen, Per Soelberg, Ehrlich, S. D. & Pedersen, Oluf Borbye, 2023, In: Genome Medicine. 15, 17 p., 1.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery

    Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide

    Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Meier, J. J., Holst, Jens Juul & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 11, p. 3079-3092

    Research output: Contribution to journal › Review › Research › peer-review

  37. Published

    The influence of insulin-related genetic variants on fetal growth, fetal blood flow, and placental weight in a prospective pregnancy cohort

    Reim, Pauline Kromann, pjx571, pjx571, Gybel-Brask, D., Schnurr, T. M., Kelstrup, Louise, Høgdall, Estrid Vilma Solyom & Hansen, Torben, 2023, In: Scientific Reports. 13, 10 p., 19638.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The national child odontology registry (SCOR): a valuable resource for odontological and public health research

    Nygaard, Nikoline, Ängquist, Lars, Midjord-Belstrøm, Daniel, Stankevic, Evelina, Hansen, Torben, Olsen, A., Rosing, Kasper & Markvart, Merete, 2023, In: BMC Oral Health. 23, 13 p., 608.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

    Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, Joachim, Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The potential of tailoring the gut microbiome to prevent and treat cardiometabolic disease

    Chakaroun, R. M., Olsson, L. M. & Bäckhed, F., 2023, In: Nature Reviews Cardiology. 20, p. 217-235

    Research output: Contribution to journal › Review › Research › peer-review

  41. Published

    The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes

    Huerta-Chagoya, A., Schroeder, P., Mandla, R., Deutsch, A. J., Zhu, W., Petty, L., Yi, X., Cole, J. B., Udler, M. S., Dornbos, P., Porneala, B., DiCorpo, D., Liu, C. T., Li, J. H., Szczerbiński, L., Kaur, V., Kim, J., Lu, Y., Martin, A., Eizirik, D. L. & 31 others, Marchetti, P., Marselli, L., Chen, L., Srinivasan, S., Todd, J., Flannick, J., Gubitosi-Klug, R., Levitsky, L., Shah, R., Kelsey, M., Burke, B., Dabelea, D. M., Divers, J., Marcovina, S., Stalbow, L., Loos, Ruth, Darst, B. F., Kooperberg, C., Raffield, L. M., Haiman, C., Sun, Q., McCormick, J. B., Fisher-Hoch, S. P., Ordoñez, M. L., Meigs, J., Baier, L. J., González-Villalpando, C., González-Villalpando, M. E., Orozco, L., García-García, L. & Mexican Biobank, M. B., 2023, In: Diabetologia. 66, p. 1273-1288 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The social origins of obesity within and across generations

    Hemmingsson, E., Nowicka, P., Ulijaszek, S. & Sørensen, Thorkild I.A., 2023, In: Obesity Reviews. 24, 1, 11 p., e13514.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    Time of day determines postexercise metabolism in mouse adipose tissue

    Pendergrast, L. A., Lundell, L. S., Ehrlich, Amy M, Ashcroft, Stephen Paul, Schönke, M., Basse, A. L., Krook, A., Treebak, Jonas Thue, Dollet, L. & Zierath, Juleen R, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 8, e2218510120.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Timeless spaces: Field experiments in the physiological study of circadian rhythms, 1938–1963

    Hussey, Kristin D., 2023, In: History and Philosophy of the Life Sciences. 45, 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Tracing the biological roots of obesity resistance in humans

    Lund, Jens, 2023, In: Nature Reviews Endocrinology. 19, p. 500 1 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  46. Published

    Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation

    Pikkupeura, Laura Maarit, Bardini Bressan, Raul, Guiu, J., Chen, Y., Maimets, Martti, Mayer, Daniela, Schweiger, P. J., Hansen, Stine Lind, Maciag, Grzegorz Jerzy, Larsen, Hjalte List, Lõhmussaar, Kadi, Pedersen, M. T., Teves, Joji Marie Yap, Lange, Jette Bornholdt, Benes, V., Sandelin, Albin Gustav & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 16 p., eadf9460.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Transient changes to metabolic homeostasis initiate mitochondrial adaptation to endurance exercise

    Dent, J. R., Stocks, Ben Nicholas, Campelj, D. G. & Philp, A., 2023, In: Seminars in Cell and Developmental Biology. 143, p. 3-16

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists

    Umapathysivam, M. M., Araldi, E., Hastoy, B., Dawed, A. Y., Vatandaslar, H., Sengupta, S., Kaufmann, A., Thomsen, S., Hartmann, B., Jonsson, A. E., Kabakci, H., Thaman, S., Grarup, N., Have, C. T., Færch, K., Gjesing, A. P., Nawaz, S., Cheeseman, J., Neville, M. J., Pedersen, O. & 12 others, Walker, M., Jennison, C., Hattersley, A. T., Hansen, Torben, Karpe, F., Holst, Jens Juul, Jones, A. G., Ristow, M., McCarthy, M. I., Pearson, E. R., Stoffel, M. & Gloyn, A. L., 2023, medRxiv, 35 p.

    Research output: Working paper › Preprint › Research

  49. Published

    Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets

    Bacos, K., Perfilyev, A., Karagiannopoulos, A., Cowan, E., Ofori, J. K., Bertonnier-Brouty, L., Rönn, T., Lindqvist, A., Luan, C., Ruhrmann, S., Ngara, M., Nilsson, Å., Gheibi, S., Lyons, C. L., Lagerstedt, J. O., Barghouth, M., Esguerra, J. L. S., Volkov, P., Fex, M., Mulder, H. & 7 others, Wierup, N., Krus, U., Artner, I., Eliasson, L., Prasad, R. B., Cataldo Bascunan, Luis Rodrigo & Ling, C., 2023, In: Journal of Clinical Investigation. 133, 4, 17 p., e163612.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Unanswered questions about the causes of obesity

    Speakman, J. R., Sørensen, Thorkild I.A., Hall, K. D. & Allison, D. B., 2023, In: Science. 381, 6661, p. 944-946 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Uncovering CNS access of lipidated exendin-4 analogues by quantitative whole-brain 3D light sheet imaging

    Skovbjerg, G., Roostalu, U., Salinas, C. G., Skytte, J. L., Perens, J., Clemmensen, Christoffer, Elster, L., Frich, C. K., Hansen, H. H. & Hecksher-Sørensen, J., 2023, In: Neuropharmacology. 238, 109637.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Unravelling Effects of Rosemary (Rosmarinus officinalis L.) Extract on Hepatic Fat Accumulation and Plasma Lipid Profile in Rats Fed a High-Fat Western-Style Diet

    Madsen, S., Bak, S. Y., Yde, C. C., Jensen, H. M., Knudsen, T. A., Bæch-Laursen, C., Holst, Jens Juul, Laustsen, C. & Hedemann, M. S., 2023, In: Metabolites. 13, 9, 21 p., 974.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Usefulness of Heat Map Explanations for Deep-Learning-Based Electrocardiogram Analysis

    Storås, A. M., Andersen, O. E., Lockhart, S., Thielemann, Roman, Gnesin, Filip Jurijevitj, Thambawita, Vajira Lasantha Bandara, Hicks, S. A., Kanters, Jørgen K., Strümke, I., Halvorsen, P. & Riegler, M. A., 2023, In: Diagnostics. 13, 14, 11 p., 2345.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Variants in EFCAB7 underlie nonsyndromic postaxial polydactyly

    Bilal, M., Khan, H., Khan, M. J., Haack, T. B., Buchert, R., Liaqat, K., Ullah, K., Ahmed, S., Bharadwaj, T., Acharya, A., Peralta, S., Najumuddin, Ali, H., Hasni, M. S., Schrauwen, I., Ullah, A., Ahmad, W. & Leal, S. M., 2023, In: European Journal of Human Genetics. 31, 11, p. 1270-1274

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Weight loss by calorie restriction does not alter appetite-regulating gut hormone responses from perfused rat small intestine

    Gerstenberg, M. K., Andersen, Daniel Bjørklund, Torz, L., Castorena, C. M., Bookout, A. L., Hartmann, Bolette, Rehfeld, Jens Frederik, Petersen, N., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2023, In: Acta Physiologica. 238, 1, 12 p., e13947.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function

    Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Lundgren, J. R., Martinussen, C., Wiingaard, C., Knudsen, C., Frikke-Schmidt, Ruth, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Obesity. 31, 4, p. 977-989 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    What is really known about the effects of nicotinamide riboside supplementation in humans

    Damgaard, Mads Vargas & Treebak, Jonas Thue, 2023, In: Science Advances. 9, 29, 12 p., eadi4862.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Whole exome sequencing identified a novel splice donor site variant in interleukin 2 receptor alpha chain

    Waheed, N., Naseer, M., Haider, N., Suleman, Sufyan & Ullah, A., 2023, In: Immunogenetics. 75, p. 71-79

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. 2022
  60. Published

    Elucidating the relationship between migraine risk and brain structure using genetic data

    International Headache Genetics Consortium, I. H. G. C., 1 Sep 2022, In: Brain. 145, 9, p. 3214-3224 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial

    Andersen, E., Juhl, C. R., Kjøller, E. T., Lundgren, J. R., Janus, C., Dehestani, Y., Saupstad, M., Ingerslev, L. R., Duun, O. M., Jensen, Simon Birk Kjær, Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten, Torekov, Signe Sørensen & Barrès, Romain, May 2022, In: Human Reproduction. 37, 7, p. 1414–1422 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    "The Waste of Daylight": Rhythmicity, Workers' Health and Britain's Edwardian Daylight Saving Time Bills

    Hussey, Kristin D., 2022, In: Social History of Medicine. 35, 2, p. 422-443 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes

    Gjesing, A. P., Engelbrechtsen, L., Cathrine B. Thuesen, A., Have, C. T., Hollensted, M., Grarup, N., Linneberg, A., Steen Nielsen, J., Christensen, L. B., Thomsen, R. W., Johansson, K. E., Cagiada, M., Gersing, S., Hartmann-Petersen, R., Lindorff-Larsen, K., Vaag, A., Sørensen, H. T., Brandslund, I., Beck-Nielsen, H., Pedersen, O. & 2 others, Rungby, Jørgen & Hansen, Torben, 2022, In: Diabetes Research and Clinical Practice. 194, 9 p., 110159.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    ADAMTS1, MPDZ, MVD, and SEZ6: candidate genes for autosomal recessive nonsyndromic hearing impairment

    Bharadwaj, T., Schrauwen, I., Rehman, S., Liaqat, K., Acharya, A., Giese, A. P. J., Nouel-Saied, L. M., Nasir, A., Everard, J. L., Pollock, L. M., Zhu, S., Bamshad, M. J., Nickerson, D. A., Ali, R. H., Ullah, A., Wali, A., Ali, G., Santos-Cortez, R. L. P., Ahmed, Z. M., McDermott, B. M. & 4 others, Ansar, M., Riazuddin, S., Ahmad, W. & Leal, S. M., 2022, In: European Journal of Human Genetics. 30, p. 22-33

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    MYC mRNA expression throughout the intestine is not associated with body mass index or type 2 diabetes

    Ellegaard, A. & Knop, Filip Krag, 2022, In: Endocrinology, Diabetes and Metabolism. 5, 2, 4 p., 00327.

    Research output: Contribution to journal › Comment/debate › Research

  66. Published

    A glucose-insulin-glucagon coupled model of the isoglycemic intravenous glucose infusion experiment

    Subramanian, V., Bagger, J. I., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Frontiers in Physiology. 13, 20 p., 911616.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

    Ramdas, S., Judd, J., Graham, S. E., Kanoni, S., Wang, Y., Surakka, I., Wenz, B., Clarke, S. L., Chesi, A., Wells, A., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K. H. H., Ntalla, I., Hui, Q., Klarin, D. & 32 others, Hilliard, A. T., Wang, Z., Xue, C., Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Hwang, M. Y., Han, S., Zhao, J. H., Aadahl, Mette, Bork-Jensen, J., Møllehave, L. T., Liu, J., Wang, J., drb459, drb459, Jackson, R. D., Kovacs, P., Pedersen, Oluf Borbye, Hansen, Torben, Lind, L., Loos, Ruth, Christensen, K., Linneberg, Allan René, Grarup, Niels, Dantoft, T. M., Karpe, F., Wei, W. Q., Sun, Y. V., Million Veterans Program, M. V. P. & Global Lipids Genetics Consortium, G. L. G. C., 2022, In: American Journal of Human Genetics. 109, 8, p. 1366-1387 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    A novel homozygous variant in the GLI1 underlies postaxial polydactyly in a large consanguineous family with intra familial variable phenotypes

    Bakar, A., Ullah, A., Bibi, N., Khan, H., Rahman, A. U., Ahmad, W. & Khan, B., 2022, In: European Journal of Medical Genetics. 65, 10, 104599.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    A novel nonsense variant in EXOC8 underlies a neurodevelopmental disorder

    Ullah, A., Krishin, J., Haider, N., Aurangzeb, B., Abdullah, Suleman, Sufyan, Ahmad, W., Hansen, Torben & Basit, S., 2022, In: Neurogenetics. 23, p. 203-212

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals

    Jensen, J. B., Dollerup, O. L., Møller, A. B., Billeskov, T. B., Kellezi, Emilie Dalbram, Chubanava, Sabina, Damgaard, Mads Vargas, Dellinger, R. W., Trošt, K., Moritz, Thomas, Ringgaard, S., Møller, N., Treebak, Jonas Thue, Farup, J. & Jessen, N., 2022, In: JCI insight. 7, 19, 15 p., e158314.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    A saturated map of common genetic variants associated with human height

    Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y. & 37 others, Karaderi, Tugce, Lin, K., Lull, K., Malden, D. E., Lepola, Mette Andersen, Appadurai, V., Bork-Jensen, J., Burgdorf, Kristoffer Sølvsten, Hansen, Thomas Folkmann, Jonsson, Anna Elisabet, Jorgensen, T., Liu, J., Møllehave, Line Tang, Smit, Roelof Adriaan Johan, Zhao, J., Bisgaard, H., Bønnelykke, Klaus, Dantoft, T. M., Grarup, Niels, Hansen, Torben, Jackson, R. D., Karpe, F., Kovacs, P., Lind, L., Linneberg, Allan René, Pedersen, Oluf Borbye, Werge, Thomas, Sun, Y., Loos, Ruth, Winkler, T. W., 23andMe Res Team, 2. R. T., VA Million Vet Program, V. M. V. P., DiscovEHR DiscovEHR MyCode Communi, D. D. M. C., eEMERGE Elect Med Records Genomics, E. E. M. R. G., LifeLines Cohort Study, L. C. S., PRACTICAL consortium, P. C. & Understanding Soc Sci Grp, U. S. S. G., 2022, In: Nature. 610, p. 704–712

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers

    Xu, R., Höß, C., Swiercz, J. M., Brandt, D. T., Lutz, V., Petersen, N., Li, R., Zhao, D., Oleksy, A., Creigh-Pulatmen, T., Trokter, M., Fedorova, M., Atzberger, A., Strandby, R. B., Olsen, A. A., Achiam, M. P., Matthews, D., Huber, M., Gröne, H-J., Offermanns, S. & 1 others, Worzfeld, T., 2022, In: Science Translational Medicine. 14, 654, eabf1922.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    A single-cell atlas of human and mouse white adipose tissue

    Emont, M. P., Jacobs, C., Essene, A. L., Pant, D., Tenen, D., Colleluori, G., Di Vincenzo, A., Jørgensen, A. M., Dashti, H., Stefek, A., McGonagle, E., Strobel, S., Laber, S., Agrawal, S., Westcott, G. P., Kar, A., Veregge, M. L., Gulko, A., Srinivasan, H., Kramer, Z. & 18 others, De Filippis, E., Merkel, E., Ducie, J., Boyd, C. G., Gourash, W., Courcoulas, A., Lin, S. J., Lee, B. T., Morris, D., Tobias, A., Khera, A. V., Claussnitzer, M., Pers, Tune H, Giordano, A., Ashenberg, O., Regev, A., Tsai, L. T. & Rosen, E. D., 2022, In: Nature. 603, p. 926-933

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    A systems biology approach to study non-alcoholic fatty liver (NAFL) in women with obesity

    Meijnikman, A. S., Lappa, D., Herrema, H., Aydin, O., Krautkramer, K. A., Tremaroli, V., Olofsson, L. E., Lundqvist, A., Bruin, S., Acherman, Y., Verheij, J., Hjorth, Siv Annegrethe, Gerdes, V. E. A., Schwartz, Thue W., Groen, A. K., Bäckhed, F., Nielsen, J. & Nieuwdorp, M., 2022, In: iScience. 25, 8, 18 p., 104828.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    ADRA1A–Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP

    Rahbani, J. F., Scholtes, C., Lagarde, D. M., Hussain, M. F., Roesler, A., Dykstra, C. B., Bunk, J., Samborska, B., O’Brien, S. L., Tripp, E., Pacis, A., Angueira, A. R., Johansen, O. S., Cinkornpumin, J., Hossain, I., Lynes, M. D., Zhang, Y., White, A. P., Pastor, W. A., Chondronikola, M. & 12 others, Sidossis, L., Klein, S., Kralli, A., Cypess, A. M., Pedersen, S. B., Jessen, N., Tseng, Y. H., Gerhart-Hines, Zach, Seale, P., Calebiro, D., Giguère, V. & Kazak, L., 2022, In: Nature Metabolism. 4, 11, p. 1459-1473

    Research output: Contribution to journal › Letter › Research › peer-review

  76. Published

    Actions of glucagon-like peptide-1 receptor ligands in the gut

    Holst, Jens Juul, Andersen, Daniel Bjørklund & Grunddal, Kaare Villum, 2022, In: British Journal of Pharmacology. 179, 4, p. 727-742

    Research output: Contribution to journal › Review › Research › peer-review

  77. Published

    Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction

    Tang, X., Rönnberg, E., Säfholm, J., Thulasingam, M., Trauelsen, Mette, Schwartz, Thue W., Wheelock, C. E., Dahlén, S. E., Nilsson, G. & Haeggström, J. Z., 2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 77, 9, p. 2677-2687

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Acute and long-term effects of psilocybin on energy balance and feeding behavior in mice

    Fadahunsi, N., Lund, Jens, Breum, Alberte Wollesen, Mathiesen, C. V., Larsen, I. B., Knudsen, Gitte Moos, Klein, A. B. & Clemmensen, Christoffer, 2022, In: Translational Psychiatry. 12, 12 p., 330.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls

    Andersen, A., Jørgensen, P. G., Bagger, J., Baldassarre, M. P. A., Christensen, Mikkel Bring, Pedersen-Bjergaard, Ulrik, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Diabetes, Obesity and Metabolism. 24, 6, p. 1123-1131

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Acute concomitant GIP receptor antagonism during GLP-1 receptor agonism does not affect appetite, resting energy expenditure or food intake in patients with type 2 diabetes and overweight/obesity

    Stensen, S., Krogh, L. L., wbf943, wbf943, Dela, Flemming, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, Mikkel Bring, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 9, p. 1882-1887

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Acute effects of linagliptin on intact and total glucagon-like peptide-1 and gastric inhibitory polypeptide levels in insulin-dependent type 2 diabetes patients with and without moderate renal impairment

    Meier, J. J., Quast, D. R., Nauck, M. A., Schenker, N., Deacon, Carolyn F., Holst, Jens Juul, Plum-Mörschel, L. & Kapitza, C., 2022, In: Diabetes, Obesity and Metabolism. 24, 5, p. 806-815

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Acute effects on glucose tolerance by neprilysin inhibition in patients with type 2 diabetes

    Albrechtsen, Nicolai Jacob Wewer, Møller, A., Martinussen, C., Gluud, Lise Lotte, Rashu, E. B., Richter, Michael Martin, Plomgaard, Peter Stendahl, Goetze, Jens P. , Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2022, In: Diabetes, Obesity and Metabolism. 24, 10, p. 2017-2026 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Adipose Tissue, Bile Acids, and Gut Microbiome Species Associated With Gallstones After Bariatric Surgery

    Guman, M. S. S., Hoozemans, J. B., Haal, S., de Jonge, P. A., Aydin, Lappa, D., Meijnikman, A. S., Westerink, F., Acherman, Y., Bäckhed, F., de Brauw, M., Nielsen, J., Nieuwdorp, M., Groen, A. K. & Gerdes, V. E. A., 2022, In: Journal of Lipid Research. 63, 11, 9 p., 100280.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Amplicon sequencing demonstrates comparable follicular mycobiomes in patients with hidradenitis suppurativa compared with healthy controls

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Egeberg, Alexander, Ingham, Andreas, Vedel Nielsen, H., Frew, J. W., Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 7, p. e580-e583 4 p.

    Research output: Contribution to journal › Comment/debate › Research

  85. Published

    An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention

    Jørsboe, E., Andersen, M. K., Skotte, L., Stæger, F. F., Færgeman, N. J., Hanghøj, K., Santander, C. G., Senftleber, N. K., Diaz, L. J., Overvad, M., Waples, R. K., Geller, F., Bjerregaard, P., Melbye, M., Larsen, C. V. L., Feenstra, B., Anders Koch, K., Jørgensen, M. E., Grarup, N., Moltke, I. & 2 others, Albrechtsen, Anders & Hansen, Torben, 2022, In: Human Genetics and Genomics Advances. 3, 4, 10 p., 100118.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    An adult-based genetic risk score for hepatic fat associates with liver and lipid traits in Danish children and adolescents

    Huang, Yun, Stinson, Sara, Juel, H. B., Lund, Morten Asp Vonsild, Holm, L. A., Fonvig, Cilius Esmann, Grarup, Niels, Pedersen, Oluf Borbye, Christiansen, Michael, Krag, A., Stender, S., Holm, Jens-Christian & Hansen, Torben, 2022, In: Journal of Hepatology. 77, p. S450-S450 1 p., FRI104.

    Research output: Contribution to journal › Conference abstract in journal › Research

  87. Published

    An integrated model of obesity pathogenesis that revisits causal direction

    Ludwig, D. S. & Sørensen, Thorkild I.A., 2022, In: Nature Reviews Endocrinology. 18, p. 261-262 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  88. Published

    Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits—The Hispanic/Latino Anthropometry Consortium

    Fernández-Rhodes, L., Graff, M., Buchanan, V. L., Justice, A. E., Highland, H. M., Guo, X., Zhu, W., Chen, H. H., Young, K. L., Adhikari, K., Palmer, N. D., Below, J. E., Bradfield, J., Pereira, A. C., Glover, L. S., Kim, D., Lilly, A. G., Shrestha, P., Thomas, A. G., Zhang, X. & 96 others, Chen, M., Chiang, C. W. K., Pulit, S., Horimoto, A., Krieger, J. E., Guindo Martínez, Marta, Preuss, M., Schumann, C., Smit, R. A. J., Torres-Mejía, G., Acuña-Alonzo, V., Bedoya, G., Bortolini, M. C., Canizales-Quinteros, S., Gallo, C., González-José, R., Poletti, G., Rothhammer, F., Hakonarson, H., Igo, R., Adler, S. G., Iyengar, S. K., Nicholas, S. B., Gogarten, S. M., Isasi, C. R., Papnicolaou, G., Stilp, A. M., Qi, Q., Kho, M., Smith, J. A., Langefeld, C. D., Wagenknecht, L., Mckean-Cowdin, R., Gao, X. R., Nousome, D., Conti, D. V., Feng, Y., Allison, M. A., Arzumanyan, Z., Buchanan, T. A., Ida Chen, Y. D., Genter, P. M., Goodarzi, M. O., Hai, Y., Hsueh, W., Ipp, E., Kandeel, F. R., Lam, K., Li, X., Nadler, J. L., Raffel, L. J., Roll, K., Sandow, K., Tan, J., Taylor, K. D., Xiang, A. H., Yao, J., Audirac-Chalifour, A., de Jesus Peralta Romero, J., Hartwig, F., Horta, B., Blangero, J., Curran, J. E., Duggirala, R., Lehman, D. E., Puppala, S., Fejerman, L., John, E. M., Aguilar-Salinas, C., Burtt, N. P., Florez, J. C., García-Ortíz, H., González-Villalpando, C., Mercader, J., Orozco, L., Tusié-Luna, T., Blanco, E., Gahagan, S., Cox, N. J., Hanis, C., Butte, N. F., Cole, S. A., Comuzzie, A. G., Voruganti, V. S., Rohde, R., Wang, Y., Sofer, T., Ziv, E., Grant, S. F. A., Ruiz-Linares, A., Rotter, J. I., Haiman, C. A., Parra, E. J., Cruz, M., Loos, Ruth & North, K. E., 2022, In: Human Genetics and Genomics Advances. 3, 2, 21 p., 100099.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Arginine-induced glucagon secretion and glucagon-induced enhancement of amino acid catabolism are not influenced by ambient glucose levels in mice

    Maruszczak, K., Rasmussen, C., Ceutz, F. R., Ørgaard, A., Elmelund, E., Richter, Michael Martin, Holst, Jens Juul, Winther-Sørensen, Marie & Albrechtsen, Nicolai Jacob Wewer, 2022, In: American Journal of Physiology - Endocrinology and Metabolism. 323, p. E207–E214

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Association of apolipoprotein M and sphingosine-1-phosphate with brown adipose tissue after cold exposure in humans

    Borup, A., Donkin, I., Boon, M. R., Frydland, M., Martinez-Tellez, B., Loft, A., Keller, S. H., Kjær, Andreas, Kjærgaard, Jesper, Hassager, Christian, Barrès, Romain, Rensen, P. C. N. & Christoffersen, Christina, 2022, In: Scientific Reports. 12, 1, 11 p., 18753.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Association of general health and lifestyle factors with the salivary microbiota – Lessons learned from the ADDITION-PRO cohort

    Poulsen, C. S., Nygaard, Nikoline, Constancias, F., Stankevic, Evelina, Kern, T., Witte, D. R., Vistisen, D., Grarup, Niels, Pedersen, Oluf Borbye, Midjord-Belstrøm, Daniel & Hansen, Torben, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 15 p., 1055117.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Association of milk intake with hay fever, asthma, and lung function: a Mendelian randomization analysis

    Skaaby, T., Kilpeläinen, Tuomas O., Mahendran, Y., Huang, L. O., Sallis, H., Thuesen, B. H., Kårhus, L. L., Leth-Møller, K. B., Grarup, Niels, Hansen, Torben, Pedersen, Oluf Borbye, Burgess, S., Munafò, M. R. & Linneberg, Allan René, 2022, In: European Journal of Epidemiology. 37, p. 713-722

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Asthma and Wheeze Severity and the Oropharyngeal Microbiota in Children and Adolescents

    Thorsen, J., Stokholm, J., Rasmussen, M. A., Roggenbuck-Wedemeyer, M., Vissing, N. H., Mortensen, M. S., Brejnrod, A. D., Fleming, L., Bush, A., Roberts, G., Singer, F., Frey, U., Hedlin, G., Nordlund, B., Murray, C. S., Abdel-Aziz, M. I., Hashimoto, S., van Aalderen, W., Maitland-van der Zee, A. H., Shaw, D. & 13 others, Fowler, S. J., Sousa, A., Sterk, P. J., Chung, K. F., Adcock, I. M., Djukanovic, R., Auffray, C., Bansal, A. T., Wagers, S., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Sørensen, Søren Johannes & Bisgaard, H., 2022, In: Annals of the American Thoracic Society. 19, 12, p. 2031-2043 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis

    Sato, S., Dyar, K. A., Treebak, J. T., Jepsen, S. L., Ehrlich, A. M., Ashcroft, S. P., Trost, K., Kunzke, T., Prade, V. M., Small, L., Basse, A. L., Schönke, M., Chen, S., Samad, M., Baldi, P., Barrès, R., Walch, A., Moritz, T., Holst, J. J., Lutter, D. & 2 others, Zierath, Juleen R & Sassone-Corsi, P., 2022, In: Cell Metabolism. 34, 2, p. 329-345.e8 26 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2

    Holm, Stephanie Kjærulff, Husted, Anna Sofie, Skov, Louise Julie, Morville, T. H., Hagemann, C. A., Jorsal, T., Dall, M., Jakobsen, A., Klein, A. B., Treebak, Jonas Thue, Knop, Filip Krag, Schwartz, Thue W., Clemmensen, Christoffer & Holst, Birgitte, 2022, In: Endocrinology. 163, 6, 13 p., bqac038.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Bile acid-farnesoid X receptor-fibroblast growth factor 19 axis in patients with short bowel syndrome: The randomized, glepaglutide phase 2 trial

    Hvistendahl, M. K., Naimi, R. M., Hansen, S. H., Rehfeld, Jens Frederik, Kissow, Hannelouise, Pedersen, Jens, Dragsted, Lars Ove, Sonne, D. P., Knop, Filip Krag & Jeppesen, Palle Bekker, 2022, In: Journal of Parenteral and Enteral Nutrition. 46, 4, p. 923-935 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Binge drinking induces an acute burst of markers of hepatic fibrogenesis (PRO-C3)

    Torp, N., Israelsen, M., Nielsen, M. J., Åstrand, C. P., Juhl, P., Johansen, S., Hansen, C. D., Madsen, B., Villesen, I. F., Leeming, D. J., Thiele, M., Hansen, Torben, Karsdal, M. & Krag, A., 2022, In: Liver International. 42, 1, p. 92-101

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis

    Neopane, K., Kozlov, N., Negoita, F., Murray-Segal, L., Brink, R., Hoque, A., Ovens, A. J., Tjin, G., McAloon, L. M., Yu, D., Ling, N. X. Y., Sanders, M. J., Oakhill, J. S., Scott, J. W., Steinberg, G. R., Loh, K., Kemp, B. E., Sakamoto, Kei & Galic, S., 2022, In: Cell Reports. 41, 12, 26 p., 111862.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells

    Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Williams, K., Barrès, Romain & Billestrup, Nils, 2022, In: Journal of Biological Chemistry. 298, 9, 14 p., 102312.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Can we target obesity using a single-cell atlas of adipose tissue?

    Schéele, Camilla Charlotte Nielsen & Nielsen, S., 2022, In: Med. 3, 5, p. 276-278 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  101. Published

    Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation

    Wei, T-T., Chandy, M., Nishiga, M., Zhang, A., Kumar, K. K., Thomas, D., Manhas, A., Rhee, S., Justesen, J. M., Chen, I. Y., Wo, H-T., Khanamiri, S., Yang, J. Y., Seidl, F. J., Burns, N. Z., Liu, C., Sayed, N., Shie, J-J., Yeh, C-F., Yang, K-C. & 5 others, Lau, E., Lynch, K. L., Rivas, M., Kobilka, B. K. & Wu, J. C., 2022, In: Cell. 185, 10, p. 1676-1693.e23

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Carbon source availability drives nutrient utilization in CD8+ T cells

    Kaymak, I., Luda, Katarzyna Maria, Duimstra, L. R., Ma, E. H., Longo, J., Dahabieh, M. S., Faubert, B., Oswald, B. M., Watson, M. J., Kitchen-Goosen, S. M., DeCamp, L. M., Compton, S. E., Fu, Z., DeBerardinis, R. J., Williams, K. S., Sheldon, R. D. & Jones, R. G., 2022, In: Cell Metabolism. 34, 9, p. 1298-1311 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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