Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2001
  2. Published

    The association between the val/ala-55 polymorphism of the uncoupling protein 2 gene and exercise efficiency

    Buemann, B., Schierning, B., Toubro, S., Bibby, B. M., Sørensen, Thorkild I.A., Dalgaard, L., Pedersen, Oluf Borbye & Astrup, A., 2001, In: International Journal of Obesity. 25, p. 467-471 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2000
  4. Published

    Studies of the variability of the genes encoding the insulin-like growth factor I receptor and its ligand in relation to type 2 diabetes mellitus

    Rasmussen, S. K., Lautier, C., Hansen, L., Echwald, S. M., Hansen, Torben, Ekstrøm, Claus Thorn, Urhammer, Søren Asger, Borch-Johnsen, K., Grigorescu, F., Smith, R. J. & Pedersen, Oluf Borbye, 1 Dec 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, 4, p. 1606-1610 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Interaktion mellem warfarin og oral miconazol-gel

    Ogard, C. G. & drb459, drb459, 9 Oct 2000, In: Ugeskrift for Laeger. 162, 41, p. 5511

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Chemokines and chemokine receptors in inflammation of the nervous system: manifold roles and exquisite regulation

    Huang, D., Han, Y., Rani, M. R., Glabinski, A., Trebst, C., Sørensen, Torben Lykke, Tani, M., Wang, J., Chien, P., O'Bryan, S., Bielecki, B., Zhou, Z., Majumder, S. & Ransohoff, R. M., Oct 2000, In: Immunological Reviews. 177, p. 52-67 16 p.

    Research output: Contribution to journal › Journal article › Research

  7. Published

    Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2

    Thulesen, J., Hartmann, Bolette, Ørskov, Cathrine, Jeppesen, Palle Bekker, Holst, Jens Juul & Poulsen, Steen Seier, Oct 2000, In: Peptides. 21, 10, p. 1511-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colon

    Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Hansen, B. S., Holst, Jens Juul, Poulsen, Steen Seier & Mortensen, P. B., Sep 2000, In: Gut. 47, 3, p. 370-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells

    Schmidt, P. T., Hartmann, Bolette, Bregenholt, S., Holst, Jens Juul & Claesson, Mogens Helweg, 1 May 2000, In: Scandinavian Journal of Gastroenterology. 35, 5, p. 522-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice

    Hartmann, Bolette, Thulesen, J., Kissow, Hannelouise, Thulesen, S., Ørskov, Cathrine, Ropke, C., Poulsen, Steen Seier & Holst, Jens Juul, 2000, In: Endocrinology. 141, 11, p. 4013-20 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 1999
  12. Published

    Diabetic intestinal growth adaptation and glucagon-like peptide 2 in the rat: effects of dietary fibre

    Thulesen, J., Hartmann, Bolette, Nielsen, C., Holst, Jens Juul & Poulsen, Steen Seier, Nov 1999, In: Gut. 45, 5, p. 672-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: Evaluation of their relation with alterations in insulin secretion and insulin sensitivity

    Almind, K., Frederiksen, S. K., Bernal, D., Hansen, Torben, Ambye, L., Urhammer, Søren Asger, Ekstrøm, Claus Thorn, Berglund, L., Reneland, R., Lithell, H., White, M. F., Van Obberghen, E. & Pedersen, Oluf Borbye, 11 Oct 1999, In: Diabetologia. 42, 10, p. 1244-1249 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Insulin resistance, exercise capacity and body composition in subjects with two hypertensive parents

    Andersen, U. B., Dige-Petersen, H., Ibsen, H., Skøtt, P., Bruun, Niels Eske, drb459, drb459 & Christiansen, C., Sep 1999, In: Journal of Hypertension. 17, 9, p. 1273-80 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Intact proinsulin and beta-cell function in lean and obese subjects with and without type 2 diabetes

    Røder, M. E., Dinesen, B., Hartling, S. G., Houssa, P., drb459, drb459, Sodoyez-Goffaux, F. & Binder, C., Apr 1999, In: Diabetes Care. Supplement. 22, 4, p. 609-14 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Implications of compound heterozygous insulin receptor mutations in congenital muscle fibre type disproportion myopathy for the receptor kinase activation

    Klein, H. H., Müller, R., drb459, drb459 & Pedersen, Oluf Borbye, Feb 1999, In: Diabetologia. 42, 2, p. 245-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Mutational analysis of the coding regions of the genes encoding protein kinase B-alpha and -beta, phosphoinositide-dependent protein kinase-1, phosphatase targeting to glycogen, protein phosphatase inhibitor-1, and glycogenin: lessons from a search for genetic variability of the insulin-stimulated glycogen synthesis pathway of skeletal muscle in NIDDM patients

    Hansen, L., Fjordvang, H., Rasmussen, S. K., drb459, drb459, Echwald, S. M., Hansen, Teis Schjals, Alessi, D., Shenolikar, S., Saltiel, A. R., Barbetti, F. & Pedersen, Oluf Borbye, Feb 1999, In: Diabetes. 48, 2, p. 403-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Studies of gene expression and activity of hexokinase, phosphofructokinase and glycogen synthase in human skeletal muscle in states of altered insulin-stimulated glucose metabolism

    drb459, drb459, Feb 1999, In: Danish Medical Bulletin (Print). 46, 1, p. 13-34 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Low incidence rate of overt hypothyroidism compared with hyperthyroidism in an area with moderately low iodine intake

    Laurberg, P., Bülow Pedersen, I., Pedersen, K. M. & drb459, drb459, Jan 1999, In: Thyroid. 9, 1, p. 33-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Alternative splicing of exon 17 and a missense mutation in exon 20 of the insulin receptor gene in two brothers with a novel syndrome of insulin resistance (congenital fiber-type disproportion myopathy)

    Vorwerk, P., Christoffersen, C. T., Müller, J., drb459, drb459, Pedersen, Oluf Borbye, De Meyts, P. & drb459, drb459, 1999, In: Hormone Research. 52, 5, p. 211-20 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Bivariant periodic cyclic homology

    Grønbæk, Christian, 1999, USA: Chapman & Hall/CRC. (Research Notes in Mathematics).

    Research output: Book/Report › Book › Research › peer-review

  22. Published

    Intermediate Expansions of a GAA Repeat in the Frataxin Gene are not associated with Type 2 Diabetes or Altered Glucose-Induced ¿-cell function in Danish Caucasians

    Dalgaard, L. T., Hansen, T., Urhammer, S. A., Clausen, J. O., Eiberg, Hans Rudolf Lytchoff & Pedersen, Oluf Borbye, 1999, In: Diabetes. 48, p. 914-917

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 1998
  24. Published

    The Ala/Va198 polymorphism of the hepatocyte nuclear factor-1α gene contributes to the interindividual variation in serum C-peptide response during an oral glucose tolerance test: Evidence from studies of 231 glucose- tolerant first degree relatives of type 2 diabetic probands

    Urhammer, Søren Asger, Hansen, Torben, Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff & Pedersen, Oluf Borbye, 1 Dec 1998, In: Journal of Clinical Endocrinology and Metabolism. 83, 12, p. 4506-4509 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1α gene on estimates of the pancreatic β-cell function in Caucasian glucosetolerant first-degree relatives of type 2 diabetic patients

    Urhammer, Søren Asger, Møller, Ann, Nyholm, B., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Clausen, J. O., Hansen, Torben, Pedersen, Oluf Borbye & Schmitz, O., 20 Nov 1998, In: Journal of Clinical Endocrinology and Metabolism. 83, 11, p. 3992-3995 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Different molecular events result in low protein levels of mannan-binding lectin in populations from southeast Africa and South America

    Madsen, H. O., Satz, M. L., Høgh, Birthe, Svejgaard, A. & Garred, Peter, 15 Sep 1998, In: Journal of immunology (Baltimore, Md. : 1950). 161, 6, p. 3169-75 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Nye farmaka til behandling af malaria

    Høgh, Birthe, 10 Aug 1998, In: Ugeskrift for Laeger. 160, 33, p. 4783-6 4 p.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Decarboxylation-based traceless linking with Aroyl acrylic acids

    Garibay, P., Nielsen, J. & Hoeg-Jensen, T., 9 Apr 1998, In: Tetrahedron Letters. 39, 15, p. 2207-2210 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The differing impact of chloroquine and pyrimethamine/sulfadoxine upon the infectivity of malaria species to the mosquito vector

    Høgh, Birthe, Gamage-Mendis, A., Butcher, G. A., Thompson, R., Begtrup, K., Mendis, C., Enosse, S. M., Dgedge, M., Barreto, J., Eling, W. & Sinden, R. E., Feb 1998, In: American Journal of Tropical Medicine and Hygiene. 58, 2, p. 176-82 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.

    Deacon, Carolyn F., Hughes, T. E. & Holst, Jens Juul, 1998, In: Diabetes. 47, p. 764-769

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity

    Deacon, Carolyn F., Knudsen, L. B., Madsen, K., Wiberg, F. C., Jacobsen, O. & Holst, Jens Juul, 1998, In: Diabetologia. 41, p. 271-278

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes

    Holst, Jens Juul & Deacon, Carolyn F., 1998, In: Diabetes. 47, p. 1663-1670

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    On the treatment of diabetes mellitus with glucagon-like peptide-1.

    Holst, Jens Juul, Deacon, Carolyn F., Toft-Nielsen, M. & Bjerre-Knudsen, L., 1998, In: Annals of the New York Academy of Sciences. 865, p. 336-343

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. 1997
  35. Published

    The Matola malaria project: a temporal and spatial study of malaria transmission and disease in a suburban area of Maputo, Mozambique

    Thompson, R., Begtrup, K., Cuamba, N., Dgedge, M., Mendis, C., Gamage-Mendis, A., Enosse, S. M., Barreto, J., Sinden, R. E. & Høgh, Birthe, Nov 1997, In: American Journal of Tropical Medicine and Hygiene. 57, 5, p. 550-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Expression of protein-tyrosine phosphatases in the major insulin target tissues

    Norris, K., Norris, F., Kono, D. H., drb459, drb459, Pedersen, Oluf Borbye, Theofilopoulos, A. N. & Møller, N. P., 6 Oct 1997, In: FEBS Letters. 415, 3, p. 243-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Chromosomal mapping and mutational analysis of the coding region of the glycogen synthase kinase-3alpha and beta isoforms in patients with NIDDM

    Hansen, L., Arden, K. C., Rasmussen, S. B., Viars, C. S., drb459, drb459, Hansen, Teis Schjals, Møller, A. M., Woodgett, J. R. & Pedersen, Oluf Borbye, Aug 1997, In: Diabetologia. 40, 8, p. 940-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Population studies of the human V kappa A18 gene polymorphism in Caucasians, blacks and Eskimos. New functional alleles and evidence for evolutionary selection of a more restricted antibody repertoire

    Juul, Lars, Hougs, L., Andersen, V., Garred, Peter, Ryder, L., Svejgaard, A., Høgh, Birthe, Lamm, L., Graugaard, B. & Barington, T., Jun 1997, In: Tissue Antigens. 49, 6, p. 595-604 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Short- and long-term metabolic effects of recombinant human IGF-I treatment in patients with severe insulin resistance and diabetes mellitus

    Vestergaard, H., Rossen, M., Urhammer, S. A., Müller, J. & Pedersen, Oluf Borbye, May 1997, In: European Journal of Endocrinology. 136, 5, p. 475-82 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Identification of a common amino acid polymorphism in the p85alpha regulatory subunit of phosphatidylinositol 3-kinase: effects on glucose disappearance constant, glucose effectiveness, and the insulin sensitivity index

    Hansen, Torben, Andersen, C. B., Echwald, S. M., Urhammer, S. A., Clausen, J. O., drb459, drb459, Owens, D., Hansen, L. & Pedersen, Oluf Borbye, Mar 1997, In: Diabetes. 46, 3, p. 494-501 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Posttranslational processing of proglucagon and postsecretory fate of proglucagon products.

    Holst, Jens Juul, Ørskov, C., Hartmann, B. & Deacon, Carolyn F., 1997, The Insulinotropic Gut Hormone Glucagon-like Peptide-1.. Basel: Karger, p. 24-48

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  42. 1996
  43. Published

    Cloning of the fomA gene, encoding the major outer membrane porin of Fusobacterium nucleatum ATCC10953

    Jensen, H. B., Skeidsvoll, J., Fjellbirkeland, A., Høgh, Birthe, Puntervoll, P., Kleivdal, H. & Tommassen, J., Nov 1996, In: Microbial Pathogenesis. 21, 5, p. 331-42 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Handedness in twins according to zygosity and chorion type: a preliminary report

    Derom, C., Thiery, E., Vlietinck, R., Loos, Ruth & Derom, R., Jul 1996, In: Behavior Genetics. 26, 4, p. 407-8 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Studies of insulin resistance in congenital generalized lipodystrophy

    Søvik, O., drb459, drb459, Trygstad, O. & Pedersen, Oluf Borbye, Jun 1996, In: Acta Paediatrica. Supplement. 413, p. 29-37 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Impaired insulin-stimulated nonoxidative glucose metabolism in glucose-tolerant women with previous gestational diabetes

    Damm, Peter, drb459, drb459, Kühl, C. E. & Pedersen, Oluf Borbye, Feb 1996, In: American Journal of Obstetrics and Gynecology. 174, 2, p. 722-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients

    Willms, B., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Nauck, M. A., Jan 1996, In: Endocrinology. 81, 1, p. 327-32 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Clinical and parasitological studies on immunity to Plasmodium falciparum malaria in children

    Høgh, Birthe, 1996, In: Scandinavian Journal of Infectious Diseases. Supplementum. 102, p. 1-53 53 p.

    Research output: Contribution to journal › Journal article › Research

  49. Published

    Gastrin release in the fetal lamb in response to luminal infusion of amniotic fluid, milk or GRP

    Sangild, Per Torp, Hilsted, L., Bjørnskov-Bartholdy, L., Holst, Jens Juul & Trahair, J. F., 1996. 1 p.

    Research output: Contribution to conference › Paper › Research

  50. Published

    Impaired insulin-stimulated nonoxidative glucose metabolism in pancreas-kidney transplant recipients: dose-response effects of insulin on glucose turnover

    Christiansen, E., drb459, drb459, Tibell, A., Hother-Nielsen, O., Holst, Jens Juul, Pedersen, O. & Madsbad, Sten, 1996, In: Diabetes. 45, 9, p. 1267-75 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Positive effects on plasma glucose & appetite by industrial modification of starch

    Raben, A., Andersen, K., Karberg, M. A., Holst, Jens Juul & Astrup, A., 1996. 1 p.

    Research output: Contribution to conference › Poster › Research

  52. 1995
  53. Published

    Interval censored survival data and multistate compartmental models in the analysis of first appearance of Plasmodium falciparum parasites in infants

    Gottschau, A. & Høgh, Birthe, 30 Dec 1995, In: Statistics in Medicine. 14, 24, p. 2727-36 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Elevation of serum insulin concentration during euglycemic hyperinsulinemic clamp studies leads to similar activation of insulin receptor kinase in skeletal muscle of subjects with and without NIDDM

    Klein, H. H., drb459, drb459, Kotzke, G. & Pedersen, Oluf Borbye, Nov 1995, In: Diabetes. 44, 11, p. 1310-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Molecular characterization of a 40-kDa outer membrane protein, FomA, of Fusobacterium periodonticum and comparison with Fusobacterium nucleatum

    Bolstad, A. I., Høgh, Birthe & Jensen, H. B., Oct 1995, In: Oral Microbiology and Immunology. 10, 5, p. 257-64 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Molecular mechanism of action of non-peptide ligands for peptide receptors

    Schwartz, Thue W., Gether, Ulrik, Schambye, H. T. & Hjorth, Siv Annegrethe, Oct 1995, In: Current Pharmaceutical Design. 1, 3, p. 325-342 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Unchanged gene expression of glycogen synthase in muscle from patients with NIDDM following sulphonylurea-induced improvement of glycaemic control

    drb459, drb459, Lund, S., Bjørbaek, C. & Pedersen, Oluf Borbye, Oct 1995, In: Diabetologia. 38, 10, p. 1230-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Insulin-resistant glucose metabolism in patients with microvascular angina--syndrome X

    drb459, drb459, Skøtt, P., Steffensen, R., Wroblewski, H., Pedersen, O. & Kastrup, J., Jul 1995, In: Metabolism. 44, 7, p. 876-82 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity

    Echwald, S. M., Bjørbaek, C., Hansen, Torben, Clausen, J. O., drb459, drb459, Zierath, Juleen R, Printz, R. L., Granner, D. K. & Pedersen, Oluf Borbye, Mar 1995, In: Diabetes. 44, 3, p. 347-53 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Antigenicity and immunogenicity of recombinant glutamate-rich protein of Plasmodium falciparum expressed in Escherichia coli

    Theisen, Michael, Vuust, J., Gottschau, A., Jepsen, S. & Høgh, Birthe, Jan 1995, In: Clinical and Vaccine Immunology. 2, 1, p. 30-4 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Cloning of a human insulin-stimulated protein kinase (ISPK-1) gene and analysis of coding regions and mRNA levels of the ISPK-1 and the protein phosphatase-1 genes in muscle from NIDDM patients

    Bjørbaek, C., Vik, T. A., Echwald, S. M., Yang, P. Y., drb459, drb459, Wang, J. P., Webb, G. C., Richmond, K., Hansen, T. & Erikson, R. L., Jan 1995, In: Diabetes. 44, 1, p. 90-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Specific and nonspecific responses to Plasmodium falciparum blood-stage parasites and observations on the gametocytemia in schoolchildren living in a malaria-endemic area of Mozambique

    Høgh, Birthe, Thompson, R., Hetzel, C., Fleck, S. L., Kruse, N. A., Jones, I., Dgedge, M., Barreto, J. & Sinden, R. E., Jan 1995, In: American Journal of Tropical Medicine and Hygiene. 52, 1, p. 50-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Sulfonylurea therapy improves glucose disposal without changing skeletal muscle GLUT4 levels in noninsulin-dependent diabetes mellitus subjects: a longitudinal study

    drb459, drb459, Weinreb, J. E., Rosen, A. S., Bjørbaek, C., Hansen, L., Pedersen, Oluf Borbye & Kahn, B. B., Jan 1995, In: The Journal of clinical endocrinology and metabolism. 80, 1, p. 270-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin

    Hansen, L., Hansen, T., drb459, drb459, Bjørbæk, C., Echwald, S. M., Clausen, J. O., Chen, Y. H., Chen, M. X., Cohen, P. T. W. & Pedersen, O., 1995, In: Human Molecular Genetics. 4, 8, p. 1313-20 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects.

    Deacon, Carolyn F., Nauck, M. A., Nielsen, M. T., Pridal, L. & Holst, Jens Juul, 1995, In: Diabetes. 44, p. 1126-1131

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Comparison of sandwich ELISA and RIA for determination of exogenous GLP-1 (7-36 amide) in plasma.

    Pridal, L., Ingwersen, S. H., Larsen, F. S., Holst, Jens Juul, Adelhorst, K. & Kirk, O., 1995, In: J Pharmaceutical and Biomedical Analysis. 13, p. 841-850

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Degradation of glucagon-like peptide-1 in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo.

    Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, p. 952-957

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Effect of 17-norleucine-VIP on gastroduodenal motility relative to serum VIP concentration and blockade of NOS.

    Holle, G. E., Steinbach, E., Wünsch, E. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. G584-G590

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Effect of endogenous hypergastrinemia on gastrin receptor expressing human colon carcinoma transplanted to athymic rats.

    Chu, M., Franzén, L., Rehfeld, J. F., Holst, Jens Juul & Borch, K., 1995, In: Today in Medicine. Gastroenterology. 109, p. 1415-1420

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus.

    Hannibal, J., Mikkelsen, J. D., Clausen, H., Holst, Jens Juul, Wulff, B. S. & Fahrenkrug, J., 1995, In: Regulatory Peptides. 55, p. 133-148

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Glucagon-like peptide 1 (7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using a-glucosidase inhibition (acarbose)

    Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Glucagon-like peptide 1 (GLP-1)(7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using alpha-glucosidase inhibition (acarbose).

    Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, C. & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Histochemical, pharmacological, biochemical and chromatographic evidence that pituitary adenylyl cyclase activating peptide is involved in inhibitory neurotransm.in the taenia of the guinea-pig caecum

    McConalogue, K., Furness, J. B., Vremec, M. A., Holst, Jens Juul, Tornøe, K. & Marley, P. D., 1995, In: J. Autonom Nerv. System. 50, p. 311-322

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Human Glucagon-like peptide-1, - six important topics.

    Holst, Jens Juul, 1995, Gastrointestinal Tract and Endocrine System.. Dordrecht/Boston/London: Kluwer Academic Publishers, p. 537-546

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  75. Published

    Human colon produces fully processed glucagon-like peptide-1 (7-36 amide).

    Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: FEBS Letters. 372, p. 269-272.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Ileal release of glucagonlike peptide-1 (GLP-1): association with inhibition of gastric acid in humans

    Layer, P., Holst, Jens Juul, Grandt, D. & Goebell, H., 1995, In: Digestive Disease Science. 40, p. 1074-82

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Increases in plasma motilin follow each episode of gallbladder emptying during the interdigestive period and changes in serum bile acid concentration correlate to plasma motilin.

    Qvist, N., Øster-Jørgensen, E., Pedersen, S. A., Rasmussen, L., Hovendal, C. & Holst, Jens Juul, 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 122-127

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Insulintropic actions of intravenous glucagon-like peptide-1 (GLP-1) (7-36 amide) in the fasting state in healthy subjects

    Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Acta Diabetologica. 32, p. 13-16

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Pharmacokinetic, insulinotropic and glucagonostatic properties of GLP-1 (7-36 amide) after subcutaneous injection in healthy volunteers. Dose-response-relationships

    Ritzel, R., Ørskov, Cathrine, Holst, Jens Juul & Nauck, M. A., 1995, In: Diabetologia. 38, p. 720-725

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Physiological augmentation of amino acid-induced insulin secretion by GIP and GLP-I but not by CCK-8

    Fieseler, P., Bridenbaugh, S., Nustede, R., Martell, J., Nauck, M. A., Ørskov, Cathrine & Holst, Jens Juul, 1995, In: Am. J. Physiol.. Vol 268, p. E949-E955

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Postprandial glucagon-like peptide-1 (GLP-1) release in states of normal and disturbed luminal nutrient digestion.

    Layer, P., v d Ohe, M. & Holst, Jens Juul, 1995, Gastrointestinal Tract and Endocrine System. Dordrecht/Boston/London: Kluwer Academic Publishers, p. 547-550

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  82. Published

    Potent inhibitory effects of transplantable rat glucagonomas and insulinomas on the respective endogenous islet cells are associated with pancreatic apoptosis.

    Blume, N., Skouv, J., Larsson, L., Holst, Jens Juul & Madsen, O. D., 1995, In: J. Clin. Invest.. 96, p. 2227-2235

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Presence of somatostatin containing neuronal-like cells in the rat pineal gland.

    Møller, M., Holst, Jens Juul, Mikkelsen, J. D. & Webb, S., 1995, In: Neuroendocrinol. Letters. 17, p. 71-80

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Secretion and effects of glucagon-like peptide-1 (GLP-1) in healthy volunteers and NIDDM subjects.

    Ørskov, C. & Holst, Jens Juul, 1995, Diabetes 1994. Elsevier Sci. Intl. Congress Series 1100, p. 513-516

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  85. Published

    Sympathoadrenal regulation of adrenocortical steroidogenesis

    Ehrhart-Bornstein, M., Bornstein, S. R., Gonzalez-Hernandez, J., Holst, Jens Juul, Watermann, M. R. & Scherbaum, W. A., 1995, In: Endocrine Research. 21, p. 13-24

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    The role of glucagon in the maintenance of euglycemia in the fed and the fasted state. Monoclonal antibody treatment as a tool in glucagon physiology in rats.

    Brand, C. L., Jørgensen, P. N., Svendsen, I., Kristensen, J. S., Knigge, U., Warberg, J. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. E469-E477

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Transplantable glucagonomas derived from pluripotent rat islet tumor tissue cause severe anorexia and adipsia

    Madsen, O. D., Karlsen, C., Blume, N., Jensen, H. I., Larsson, L. & Holst, Jens Juul, 1995, In: Scand. J. Clin. Lab. Invest.. 55, suppl. 220, p. 27-36

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. 1994
  89. Published

    Calcitonin gene-related peptide (CGRP) in the nipple of the rat mammary gland

    Thulesen, J., Rasmussen, T. N., Schmidt, P., Holst, Jens Juul & Poulsen, Steen Seier, Dec 1994, In: Histochemistry. 102, 6, p. 437-444 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Immune responses to band 3 neoantigens on Plasmodium falciparum-infected erythrocytes in subjects living in an area of intense malaria transmission are associated with low parasite density and high hematocrit value

    Høgh, Birthe, Petersen, E., Crandall, I., Gottschau, A. & Sherman, I. W., Oct 1994, In: Infection and Immunity. 62, 10, p. 4362-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Sequence of the human glycogen-associated regulatory subunit of type 1 protein phosphatase and analysis of its coding region and mRNA level in muscle from patients with NIDDM

    Chen, Y. H., Hansen, L., Chen, M., Bjørbaek, C., drb459, drb459, Hansen, Teis Schjals, Cohen, P., Pedersen, Oluf Borbye & drb459, drb459, Oct 1994, In: Diabetes. 43, 10, p. 1234-41 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Genetic variants in promoters and coding regions of the muscle glycogen synthase and the insulin-responsive GLUT4 genes in NIDDM

    Bjørbaek, C., Echwald, S. M., Hubricht, P., drb459, drb459, Hansen, Torben, Zierath, Juleen R & Pedersen, Oluf Borbye, Aug 1994, In: Diabetes. 43, 8, p. 976-83 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Glucagon-like peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man

    Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. P. & Holst, Jens Juul, Jun 1994, In: Scandinavian Journal of Gastroenterology. 29, 6, p. 501-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Peptide-evoked release of amylase from isolated acini of the rat parotid gland

    Goll, R., Poulsen, J. H., Schmidt, P., Schjoldager, B., Poulsen, Steen Seier & Holst, Jens Juul, 26 May 1994, In: Regulatory Peptides. 51, 3, p. 237-54 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    The multifactorial and multistage character of protective immunity to Plasmodium falciparum, naturally acquired by an indigenous population in Burkina Faso

    Boudin, C., Sheick, I., Chumpitazi, B., Pazart, L., Høgh, Birthe, Peyron, F., Deloron, P., Picot, S. & Ambroise-Thomas, P., Apr 1994, In: Scandinavian Journal of Immunology. 39, 4, p. 409-17 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans

    Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, Apr 1994, In: Diabetes. 43, 4, p. 535-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Effect of glucagon-like peptide-1 (proglucagon 78-107amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Ørskov, Cathrine & Holst, Jens Juul, Jan 1994, In: Metabolism. 43, 1, p. 104-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Expression of glycogen synthase and phosphofructokinase in muscle from type 1 (insulin-dependent) diabetic patients before and after intensive insulin treatment

    drb459, drb459, Andersen, P. H., Lund, S., Vedel, P. & Pedersen, Oluf Borbye, Jan 1994, In: Diabetologia. 37, 1, p. 82-90 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Atrial natriuretic peptide-like immunoreactive material (ANP-L1) is released from the adrenal gland by splanchnic nerve stimulation

    Duntas, L., Bornstein, S. R., Scherbaum, W. & Holst, Jens Juul, 1994, In: Exp.Clin.Endocrinol.. 101, p. 371-373

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Cholecystokinin is a negative regulator of gastric acid secretion and postprandial release of gastrin in humans.

    Schmidt, W. E., Schenk, S., Nustede, R., Rovati, L. C., Holst, Jens Juul, Fölsch, U. & Creutzfeldt, W., 1994, In: Today in Medicine. Gastroenterology. 107, p. 1610-1620

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Decreased postprandial thermogenesis and fat oxidation, but increased fullness after a high-fiber meal compared to a low-fiber meal

    Raben, A. B., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Clin. Nutr.. 59, p. 1386-1394

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Effect of glucagon-like peptide-1 (proglucagon 78 - 107 amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Ørskov, Cathrine & Holst, Jens Juul, 1994, In: Metabolism. 43, p. 104-108

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    Effect of glucagon-like peptide-1 (proglucagon 78-107 amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Holst, Jens Juul & Ørskov, C., 1994, In: Metabolism. 43, p. 104-108

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. Published

    Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity

    Raben, A., Andersen, H. B., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Physiol.. 267, p. E549-E559

    Research output: Contribution to journal › Journal article › Research › peer-review

  105. Published

    Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity

    Raben, Anne, Andersen, H. B., Christensen, N. J., Madsen, J., Holst, Jens Juul & Astrup, A., 1994, In: American Journal of Physiology: Endocrinology and Metabolism. 267, 4 part 1, p. E549-E559 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  106. Published

    Exendin-4 and exendin (9-39)NH*U2-agonist and antagonist, respectively, at the rat parietal cell receptor for glucagon-like peptide-1 (7-36)NH*U2

    Schepp, W., Schmidtler, J. & Holst, Jens Juul, 1994, In: Eur. J. Pharmacol.. 269, p. 183-191

    Research output: Contribution to journal › Journal article › Research › peer-review

  107. Published

    Glucagon and other proglucagon-derived peptides

    Holst, Jens Juul & Ørskov, Cathrine, 1994, Gut Peptides: Biochemistry and Physiology. New York: Raven Press, p. 305-340

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  108. Published

    Glucagon-like peptide 1: on its way to clinical application

    Göke, B., Göke, R., Holst, Jens Juul & Ørskov, C., 1994, In: Digestion. 54, p. 339-340

    Research output: Contribution to journal › Journal article › Research › peer-review

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