Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2022
  2. Published

    Causality between physical activity, sedentary behavior and obesity: A Mendelian randomization study

    Carrasquilla, Germán D., García Ureña, Mario, Fall, T., Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2022, In: European Journal of Human Genetics. 30, Supplement 1, p. 536-536 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  3. Published

    Causes of Outcome Learning: a causal inference-inspired machine learning approach to disentangling common combinations of potential causes of a health outcome

    Rieckmann, Andreas, Dworzynski, P., Arras, L., Lapuschkin, S., Samek, W., Arah, O. A., Rod, Naja Hulvej & Ekstrøm, Claus Thorn, 2022, In: International Journal of Epidemiology. 51, 5, p. 1622–1636 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Changes in BMI and physical activity from youth to adulthood distinguish normal-weight, metabolically obese adults from those who remain healthy

    Viitasalo, A., Pahkala, K., Lehtimäki, T., Viikari, J. S. A., Tammelin, T. H., Raitakari, O. & Kilpeläinen, Tuomas O., 2022, In: Frontiers in Endocrinology. 13, 7 p., 923327.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Changing genetic architecture of body mass index from infancy to early adulthood: an individual based pooled analysis of 25 twin cohorts

    Silventoinen, K., Li, W., Jelenkovic, A., Sund, R., Yokoyama, Y., Aaltonen, S., Piirtola, M., Sugawara, M., Tanaka, M., Matsumoto, S., Baker, L. A., Tuvblad, C., Tynelius, P., Rasmussen, F., Craig, J. M., Saffery, R., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Martin, N. G. & 37 others, Medland, S. E., Montgomery, G. W., Lichtenstein, P., Krueger, R. F., McGue, M., Pahlen, S., Christensen, K., Skytthe, A., Kyvik, K. O., Saudino, K. J., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Ullemar, V., Almqvist, C., Magnusson, P. K. E., Corley, R. P., Huibregtse, B. M., Knafo-Noam, A., Mankuta, D., Abramson, L., Haworth, C. M. A., Plomin, R., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Duncan, G. E., Buchwald, D., Burt, S. A., Klump, K. L., Llewellyn, C. H., Fisher, A., Boomsma, D., Sørensen, Thorkild I.A. & Kaprio, J., 2022, In: International Journal of Obesity. 46, p. 1901–1909 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Cholestasis alters brain lipid and bile acid composition and compromises motor function in neonatal piglets

    Henriksen, Nicole Lind, Hansen, S. H., Lycas, M. D., Pan, X., Eriksen, Thomas, Johansen, L. S., Sprenger, R. R., Ejsing, C. S., Burrin, D. G., Skovgaard, K., Christensen, Vibeke Brix, Thymann, Thomas & Pankratova, Stanislava, 2022, In: Physiological Reports. 10, 13, 15 p., e15368.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Circulating Soluble CD163, Associations With Cardiovascular Outcomes and Mortality, and Identification of Genetic Variants in Older Individuals: The Cardiovascular Health Study

    Durda, P., Raffield, L. M., Lange, E. M., Olson, N. C., Jenny, N. S., Cushman, M., Deichgraeber, P., Grarup, Niels, Jonsson, Anna Elisabet, Hansen, Torben, Mychaleckyj, J. C., Psaty, B. M., Reiner, A. P., Tracy, R. P. & Lange, L. A., 2022, In: Journal of the American Heart Association. 11, 21, 14 p., e024374.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Clinical Characterization of Copy Number Variants Associated with Neurodevelopmental Disorders in a Large-scale Multiancestry Biobank

    Birnbaum, R., Mahjani, B., Loos, Ruth & Sharp, A. J., 2022, In: JAMA Psychiatry. 79, 3, p. 250-259

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Clinical and genetic characterization of patients segregating variants in KPTN, MINPP1, NGLY1, AP4B1, and SON underlying neurodevelopmental disorders: Genetic and phenotypic expansion

    Ullah, A., Shah, A. A., Alluqmani, M., Haider, N., Aman, H., Alfadhli, F., Almatrafi, A. M., Albalawi, A. M., Krishin, J., Ullah Khan, F., Anjam, B. A., Abdullah, Peña Lozano, Elionora, Samad, A., Ahmad, W., Hansen, Torben, Xia, K. & Basit, S., 2022, In: International Journal of Developmental Neuroscience. 82, 8, p. 788-804

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity

    Hayashi, Y., Shimizu, I., Yoshida, Y., Ikegami, R., Suda, M., Katsuumi, G., Fujiki, S., Ozaki, K., Abe, M., Sakimura, K., Okuda, S., Hayano, T., Nakamura, K., Walsh, K., Jespersen, N. Z., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Minamino, T., 2022, In: iScience. 25, 7, 23 p., 104547.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Cold Exposure Drives Weight Gain and Adiposity following Chronic Suppression of Brown Adipose Tissue

    Aldiss, Peter Stuart Jacob, Lewis, J. E., Lupini, I., Bloor, I., Chavoshinejad, R., Boocock, D. J., Miles, A. K., Ebling, F. J. P., Budge, H. & Symonds, M. E., 2022, In: International Journal of Molecular Sciences. 23, 3, 16 p., 1869.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Colonic lactulose fermentation has no impact on glucagon-like peptide-1 and peptide-YY secretion in healthy young men

    Christiansen, Charlotte Bayer, Veedfald, Simon, Hartmann, Bolette, Gauguin, A. M., Møller, Søren, Moritz, Thomas, Madsbad, Sten & Holst, Jens Juul, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 1, p. 77-87

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Combined micro-osmotic pump infusion and intracerebroventricular injection to study FGF1 signaling pathways in the mouse brain

    Brown, Jenny, Phan, B. A., Aalling, Nadia, Morton, G. J., Schwartz, M. W. & Scarlett, J. M., 2022, In: STAR Protocols. 3, 2, 16 p., 101329.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Coming Closer to Citizens? Frustrated Dialogue on the Danish Health Authority's Facebook Page During COVID-19

    Madvig, F., Achiam, Marianne, Adler-Nissen, Rebecca, Johansen, Nicklas & Whiteley, Louise, 2022, In: Frontiers in Communication. 7, 822471.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Comparable Effects of Sleeve Gastrectomy and Roux-en-Y Gastric Bypass on Basal Fuel Metabolism and Insulin Sensitivity in Individuals with Obesity and Type 2 Diabetes

    Brodersen, K., Nielsen, M. F., Richelsen, B., Lauritzen, E. S., Pahle, E., Abrahamsen, J., Hartmann, Bolette, Holst, Jens Juul & Møller, N., 2022, In: Journal of Diabetes Research. 2022, 9 p., 5476454.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Comparative analysis of oral and intraperitoneal glucose tolerance tests in mice

    Small, Lewin Barkla, Ehrlich, Amy M, Iversen, Jo Frøkjær, Ashcroft, Stephen Paul, Trošt, K., Moritz, Thomas, Hartmann, Bolette, Holst, Jens Juul, Treebak, Jonas Thue, Zierath, Juleen R & Barrès, Romain, 2022, In: Molecular Metabolism. 57, 8 p., 101440.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Comparative analysis of sperm DNA methylation supports evolutionary acquired epigenetic plasticity for organ speciation

    Moharrek, Farideh, Ingerslev, L. R., Altıntaş, Ali, Lundell, L., Hansen, Ann Normann, Small, Lewin Barkla, Workman, C. T. & Barrès, Romain, 2022, In: Epigenomics. 14, 21, p. 1305-1324 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Context dependency of nucleotide probabilities and variants in human DNA

    Liang, Yuhu, Grønbæk, Christian, Fariselli, P. & Krogh, Anders, 2022, In: BMC Genomics. 23, 1, 15 p., 87.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Context dependent prediction in DNA sequence using neural networks

    Grønbæk, Christian, Liang, Yuhu, Elliott, Desmond & Krogh, Anders, 2022, In: PeerJ. 10, 22 p., e13666.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Culturing Impermanence at the Museum: The Metabolic Collection

    Grünfeld, Martin, 2022, Impermanenc: Exploring continuous change across cultures. Geismar, H., Otto, T. & Warner, C. D. (eds.). University College London Press

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  21. Published

    DNA Methylation and Gene Expression in Blood and Adipose Tissue of Adult Offspring of Women with Diabetes in Pregnancy - A Validation Study of DNA Methylation Changes Identified in Adolescent Offspring

    Manitta, Eleonora, Marques, I. C. F., Bredgaard, S. S., Kelstrup, Louise, Houshmand-Oeregaard, A., Clausen, Tine Dalsgaard, Grunnet, Louise Groth, Mathiesen, Elisabeth, Dalgaard, L. T., Barrès, Romain, Vaag, Allan, Damm, Peter & Hjort, Line, 2022, In: Biomedicines. 10, 6, 15 p., 1244.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    DNA methylation in blood cells is associated with cortisol levels in offspring of mothers who had prenatal post-traumatic stress disorder

    Fransquet, P. D., Hjort, Line, Rushiti, F., Wang, S. J., Krasniqi, S. P., Çarkaxhiu, S. I., Arifaj, D., Xhemaili, V. D., Salihu, M., Leku, N. A. & Ryan, J., 2022, In: Stress and Health. 38, 4, p. 755-766 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Dasiglucagon Effectively Mitigates Postbariatric Postprandial Hypoglycemia: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial

    Nielsen, C. K., Øhrstrøm, C. C., Kielgast, U. L., Hansen, D. L., Hartmann, Bolette, Holst, Jens Juul, Lund, Asger Bach, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes Care. 45, 6, p. 1476–1481

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Deciphering inhibitory activity of flavonoids against tau protein kinases: a coupled molecular docking and quantum chemical study

    Rasouli, H., Hosseini Ghazvini, S. M. B., Yarani, R., Altıntaş, Ali, Jooneghani, S. G. N. & Ramalho, T. C., 2022, In: Journal of Biomolecular Structure & Dynamics. 40, 1, p. 411-424 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    DeepFake electrocardiograms: the key for open science for artificial intelligence in medicine

    Thambawita, V., Isaksen, Jonas L., Hicks, S. A., Ghouse, Jonas, Ahlberg, Gustav, Linneberg, Allan René, Grarup, Niels, Ellervik, Christina, Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., Holstein-Rathlou, N., Strümke, I., Hammer, H. L., Maleckar, M., Halvorsen, P., Riegler, M. A. & Kanters, Jørgen K., 2022, 17 p. (medRxiv).

    Research output: Working paper › Preprint › Research

  26. Published

    Dietary Protein Restriction Improves Metabolic Dysfunction in Patients with Metabolic Syndrome in a Randomized, Controlled Trial

    Ferraz-Bannitz, R., Beraldo, R. A., Peluso, A., Dall, M., Babaei, P., Foglietti, R. C., Martins, L. M., Gomes, P. M., Marchini, J. S., Miguel Suen, V. M., Conti de Freitas, L. C., Navegantes, L. C., Pretti, M. A. M., Boroni, M., Treebak, Jonas Thue, Mori, M. A., Foss, M. C. & Foss-Freitas, M. C., 2022, In: Nutrients. 14, 13, 18 p., 2670.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes: A randomised controlled trial

    Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Chabanova, E., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Haugaard, Steen Bendix & Krarup, T., 2022, In: Diabetologia. 65, p. 506-517 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Differential Brain and Cerebrospinal Fluid Proteomic Responses to Acute Prenatal Endotoxin Exposure

    Muk (Mudi), Tik, Stensballe, A., Dmytriyeva, O., Brunse, Anders, Jiang, Pingping, Thymann, Thomas, Sangild, Per Torp & Pankratova, Stanislava, 2022, In: Molecular Neurobiology. 59, p. 2204–2218

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

    Winkler, T. W., Rasheed, H., Teumer, A., Gorski, M., Rowan, B. X., Stanzick, K. J., Thomas, L. F., Tin, A., Hoppmann, A., Chu, A. Y., Tayo, B., Thio, C. H. L., Cusi, D., Chai, J-F., Sieber, K. B., Horn, K., Li, M., Scholz, M., Cocca, M., Wuttke, M. & 31 others, van der Most, P. J., Yang, Q., Ghasemi, S., Nutile, T., Li, Y., Pontali, G., Günther, F., Dehghan, A., Correa, A., Parsa, A., Feresin, A., de Vries, A. P. J., Zonderman, A. B., Smith, A. V., Oldehinkel, A. J., De Grandi, A., Rosenkranz, A. R., Franke, A., Teren, A., Metspalu, A., Hicks, A. A., Morris, A. P., Tönjes, A., Morgan, A., Podgornaia, A. I., Christensen, K., Lind, L., Kovacs, P., Rossing, Peter, Loos, Ruth & LifeLines Cohort Study, L. C. S., 2022, In: Communications Biology . 5, p. 580 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Discovery of the GI Effects of GLP-1: An Historical Perspective

    Holst, Jens Juul, 2022, In: Digestive Diseases and Sciences. 67, p. 2716-2720

    Research output: Contribution to journal › Review › Research › peer-review

  31. Published

    Divergent Roles of α5 and β4 Nicotinic Receptor Subunits in Food Reward and Nicotine-induced Weight Loss in Male Mice

    Breum, Alberte Wollesen, Falk, S., Svendsen, C. S. A., Nicolaisen, T. S., Mathiesen, C. V., Maskos, U. & Clemmensen, Christoffer, 2022, In: Endocrinology. 163, 7, 9 p., bqac079.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Do gene-environment interactions have implications for the precision prevention of type 2 diabetes?

    Sørensen, Thorkild I.A., Metz, Sophia & Kilpeläinen, Tuomas O., 2022, In: Diabetologia. 65, p. 1804–1813 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study

    Koopen, A., Witjes, J., Wortelboer, K., Majait, S., Prodan, A., Levin, E., Herrema, H., Winkelmeijer, M., Aalvink, S., Bergman, J. J. G. H. M., Havik, S., Hartmann, B., Levels, H., Bergh, P-O., van Son, J., Balvers, M., Bastos, D. M., Stroes, E., Groen, A. K., Henricsson, M. & 8 others, Kemper, E. M., Holst, Jens Juul, Strauch, C. M., Hazen, S. L., Backhed, F., De Vos, W. M., Nieuwdorp, M. & Rampanelli, E., 2022, In: Gut. 71, p. 1577-1587 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Dynamic interplay between Afadin S1795 phosphorylation and diet regulates glucose homeostasis in obese mice

    Tozzi, M., Brown, E. L., Petersen, P. S., Lundh, M., Isidor, Marie Sophie, Plucinska, Kaja, Nielsen, Thomas Svava, Agueda Oyarzabal, Marina, Small, Lewin Barkla, Treebak, Jonas Thue & Emanuelli, Brice, 2022, In: The Journal of Physiology. 600, 4, p. 885-902

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Dynamics of the normal gut microbiota: A longitudinal one-year population study in Sweden

    Olsson, L. M., Boulund, F., Nilsson, S., Khan, M. T., Gummesson, A., Fagerberg, L., Engstrand, L., Perkins, R., Uhlén, M., Bergström, G., Tremaroli, V. & Bäckhed, F., 2022, In: Cell Host and Microbe. 30, 5, p. 726-739.e3

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance

    Pellegrinelli, V., Rodriguez-Cuenca, S., Rouault, C., Figueroa-Juarez, E., Schilbert, H., Virtue, S., Moreno-Navarrete, J. M., Bidault, G., Vázquez-Borrego, M. C., Dias, A. R., Pucker, B., Dale, M., Campbell, M., Carobbio, S., Lin, Y. H., Vacca, M., Aron-Wisnewsky, J., Mora, S., Masiero, M. M., Emmanouilidou, A. & 8 others, Mukhopadhyay, S., Dougan, G., den Hoed, M., Loos, Ruth, Fernández-Real, J. M., Chiarugi, D., Clément, K. & Vidal-Puig, A., 2022, In: Nature Metabolism. 4, 4, p. 476-494 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Early detection of childhood overweight and related complications in a Danish population-based cohort aged 2–8 years

    Frithioff-Bøjsøe, C., Lund, Morten Asp Vonsild, Lausten-Thomsen, U., Fonvig, Cilius Esmann, Lankjær, I. O. J., Hansen, T., Hansen, Torben, Baker, J. L. & Holm, Jens-Christian, 2022, In: Obesity Research and Clinical Practice. 16, 3, p. 228-234 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Early effects of Roux-en-Y gastric bypass on dietary fatty acid absorption and metabolism in people with obesity and normal glucose tolerance

    Hindsø, M., Bojsen-Møller, K. N., Kristiansen, V. B., Holst, Jens Juul, van Hall, Gerrit & Madsbad, Sten, 2022, In: International Journal of Obesity. 46, 7, p. 1359-1365

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Effect of 6 weeks of very low-volume high-intensity interval training on oral glucose-stimulated incretin hormone response

    Hindsø, M., Kuhlman, A. B., Dohlmann, T. L., Lund, M. T., Hartmann, Bolette, Holst, Jens Juul, Larsen, Steen & Helge, Jørn Wulff, 2022, In: European Journal of Sport Science. 22, 3, p. 381-389

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Effect of Meal Texture on Postprandial Glucose Excursions and Gut Hormones After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy

    Hedbäck, N., Hindsø, M., Bojsen-Møller, K. N., Linddal, A. K., Jørgensen, N. B., Dirksen, C., Møller, A., Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul, Svane, M. S. & Madsbad, Sten, 2022, In: Frontiers in Nutrition. 9, 889710.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Effects of 18-months metformin versus placebo in combination with three insulin regimens on RNA and DNA oxidation in individuals with type 2 diabetes: A post-hoc analysis of a randomized clinical trial

    Larsen, E. L., Kjær, L. K., Lundby-Christensen, L., Boesgaard, T. W., Breum, Leif, Gluud, C., Hedetoft, C., Krarup, T., Lund, S. S., Mathiesen, Elisabeth, Perrild, Hans, Sneppen, S. B., Tarnow, L., Thorsteinsson, B., drb459, drb459, Poulsen, Henrik Enghusen, Madsbad, Sten & Almdal, Thomas Peter, 2022, In: Free Radical Biology and Medicine. 178, p. 18-25 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Effects of a Lifestyle Intervention on Bone Turnover in Persons with Type 2 Diabetes: A post hoc Analysis of the U-TURN Trial

    Abildgaard, J., Johansen, M. Y., Skov-Jeppesen, Kirsa, Andersen, L. B., Karstoft, K., Hansen, K. B., Hartmann, Bolette, Holst, Jens Juul, Pedersen, Bente Klarlund & Ried-Larsen, M., 2022, In: Medicine and Science in Sports and Exercise. 54, 1, p. 38-46

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Effects of carbohydrate restriction on body weight and glycemic control in individuals with type 2 diabetes: A randomized controlled trial of efficacy in real-life settings

    Weber, P., Thomsen, M. N., fbg982, fbg982, Samkani, A., Carl, M. H., Astrup, A., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Madsbad, Sten, Magkos, Faidon, Krarup, T. & Haugaard, Steen Bendix, 2022, In: Nutrients. 14, 24, 12 p., 5244.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Effects of short-acting exenatide added three times daily to insulin therapy on bone metabolism in type 1 diabetes

    Johansen, N. J., Dejgaard, T. F., Lund, A., Schlüntz, Camilla, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Andersen, H. U. & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 2, p. 221-227

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Efficient approaches for large-scale GWAS with genotype uncertainty

    Jørsboe, E. & Albrechtsen, Anders, 2022, In: G3: Genes, Genomes, Genetics (Bethesda). 12, 1, 9 p., jkab385.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Ellagic Acid prevents vascular dysfunction in small mesenteric arteries of ovariectomized hypertensive rats

    da Silva, F. B., Romero, W. G., Rouver, W. D. N., Silva, K., de Almeida, S. A., Mengal, V., Peluso, A. A., Endlich, P. W., Bissoli, N. S., Claudio, E. R. G. & de Abreu, G. R., 2022, In: Journal of Nutritional Biochemistry. 105, 8 p., 108995.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Ellagic acid prevents myocardial infarction-induced left ventricular diastolic dysfunction in ovariectomized rats

    Costa, B. M., Mengal, V., Brasil, G. A., Peluso, A. A., Treebak, Jonas Thue, Endlich, P. W., de Almeida, S. A. & de Abreu, G. R., 2022, In: Journal of Nutritional Biochemistry. 105, 9 p., 108990.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Endogenous Glucose-Dependent Insulinotropic Polypeptide Contributes to Sitagliptin-Mediated Improvement in Beta Cell Function in Patients with Type 2 Diabetes

    Stensen, S., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Diabetes. 71, 10, p. 2209-2221

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Endurance Training in Humans Modulates the Bacterial DNA Signature of Skeletal Muscle

    Villarroel, J., Donkin, I., Champion, C., Burcelin, R. & Barrès, Romain, 2022, In: Biomedicines. 10, 1, 15 p., 64.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Endurance training improves GLP-1 sensitivity and glucose tolerance in overweight women

    Åkerström, T., Stolpe, Malene Norup, Widmer, R., Dejgaard, T. F., Højberg, J. M., Møller, Kirsten, Hansen, J. S., Trinh, B., Holst, Jens Juul, Thomsen, C., Pedersen, Bente Klarlund & Ellingsgaard, H., 2022, In: Journal of the Endocrine Society. 6, 9, p. 1-8 8 p., bvac111.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Entero-pancreatic hormone secretion, gastric emptying and glucose absorption after frequently sampled meal tests

    Veedfald, Simon, Rehfeld, Jens Frederik, van Hall, Gerrit, Svendsen, Lars Bo & Holst, Jens Juul, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 1, p. e188-e204 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Enterohepatic, gluco-metabolic, and gut microbial characterization of individuals with bile acid malabsorption

    Kårhus, M. L., Sonne, David Peick, Thomasen, M., Ellegaard, A., Holst, Jens Juul, Rehfeld, Jens Frederik, Chávez-Talavera, O., Tailleux, A., Staels, B., Nielsen, Dennis Sandris, Dragsted, Lars Ove, Vilsbøll, Tina, Brønden, A. & Knop, Filip Krag, 2022, In: Gastro Hep Advances. 1, 3, p. 299-312 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Environmentality in biomedicine: microbiome research and the perspectival body

    Formosinho, Joana, Bencard, Adam & Whiteley, Louise, 2022, In: Studies in History and Philosophy of Science. 91, p. 148-158 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Estimating the causal relationship between smoking and abdominal adiposity using Mendelian randomization

    Carrasquilla, Germán D., García Ureña, Mario, Sharma, S. & Kilpeläinen, Tuomas O., 2022, Cold Spring Harbor Laboratory, (bioRxiv).

    Research output: Working paper › Preprint › Research

  55. Published

    Ethnic and sex differences in hepatic lipid content and related cardiometabolic parameters in lean individuals

    Petersen, K. F., Dufour, S., Li, F., Rothman, D. L. & Shulman, G. I., 2022, In: JCI insight. 7, 7, 10 p., e157906.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Evaluation of commercially available glucagon receptor antibodies and glucagon receptor expression

    Billeschou, Anna, Johansen, C. D., Christensen, J. B., Kjeldsen, Sasha Alexandra Sampson, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Serizawa, R., Hornum, Mads, Porrini, E., Pedersen, Jens, Ørskov, Cathrine, Gluud, Lise Lotte, Sorensen, Charlotte Mehlin, Holst, Jens Juul, Albrechtsen, Reidar & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Communications Biology . 5, 1, 13 p., 1278.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Exenatide once weekly for alcohol use disorder investigated in a randomized, placebo-controlled clinical trial

    Klausen, M. K., Jensen, M. E., Møller, M., le Dous, N., Jensen, A-M. Ø., Zeeman, V. A., Johannsen, C-F., Lee, A. M., Thomsen, G. K., Macoveanu, J., Fisher, P. M., Gillum, M. P., Jørgensen, N. R., Bergmann, M. L., Enghusen Poulsen, H., Becker, U., Holst, J. J., Benveniste, H., Volkow, N. D., Vollstädt-Klein, S. & 5 others, Miskowiak, Kamilla, Ekstrøm, Claus Thorn, Knudsen, Gitte Moos, Visboll, T. & Fink-Jensen, Anders, 2022, In: JCI insight. 19, 20 p., e159863.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Exercise effects on γ3-AMPK activity, Akt substrate of 160 kDa phosphorylation, and glucose uptake in muscle of normal and insulin-resistant female rats

    Wang, H., Arias, E. B., Treebak, Jonas Thue & Cartee, G. D., 2022, In: Journal of Applied Physiology. 132, 1, p. 140-153 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Exercise timing influences multi-tissue metabolome and skeletal muscle proteome profiles in type 2 diabetic patients - A randomized crossover trial

    Savikj, M., Stocks, Ben Nicholas, Sato, S., Caidahl, K., Krook, A., Deshmukh, Atul Shahaji, Zierath, Juleen R & Wallberg-Henriksson, H., 2022, In: Metabolism. 135, 14 p., 155268.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Exerkines in health, resilience and disease

    Chow, L. S., Gerszten, R. E., Taylor, J. M., Pedersen, B. K., van Praag, H., Trappe, S., Febbraio, M. A., Galis, Z. S., Gao, Y., Haus, J. M., Lanza, I. R., Lavie, C. J., Lee, C-H., Lucia, A., Moro, C., Pandey, A., Robbins, J. M., Stanford, K. I., Thackray, A. E., Villeda, S. & 5 others, Watt, M. J., Xia, A., Zierath, Juleen R, Goodpaster, B. H. & Snyder, M. P., 2022, In: Nature Reviews Endocrinology. 18, p. 273-289

    Research output: Contribution to journal › Review › Research › peer-review

  61. Published

    Exome Sequencing Revealed a Novel Splice Site Variant in the CRB2 Gene Underlying Nephrotic Syndrome

    Simaab, A., Krishin, J., Alaradi, S. R., Haider, N., Shah, M., Ullah, A., Abdullah, A., Ahmad, W., Hansen, Torben & Basit, S., 2022, In: Medicina. 58, 12, 9 p., 1784.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Exome sequencing reveals the first intragenic deletion in ABCA5 underlying autosomal recessive hypertrichosis

    Raza, R., Ullah, A., Haider, N., Krishin, J., Shah, M., Khan, F. U., Abdullah, Hansen, Torben, Raza, S. I., Ahmad, W. & Basit, S., 2022, In: Clinical and Experimental Dermatology. 47, 6, p. 1137-1143

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Exploratory analysis of eating- and physical activity-related outcomes from a randomized controlled trial for weight loss maintenance with exercise and liraglutide single or combination treatment

    Jensen, Simon Birk Kjær, Janus, C., Lundgren, J. R., Juhl, C. R., Sandsdal, Rasmus Michael, Olsen, L. M., Andresen, A., Borg, S. A., Jacobsen, I. C., Finlayson, G., Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2022, In: Nature Communications. 13, 1, 11 p., 4770.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Expression Profile of the GLP-1 Receptor in the Gastrointestinal Tract and Pancreas in Adult Female Mice

    Grunddal, Kaare Villum, Jensen, E. P., Ørskov, Cathrine, Andersen, Daniel Bjørklund, Windeløv, Johanne Agerlin, Poulsen, Steen Seier, Rosenkilde, M. M., Knudsen, L. B., Pyke, C. & Holst, Jens Juul, 2022, In: Endocrinology. 163, 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    External validation of a genetic risk score that predicts development of alcohol-related cirrhosis

    Johansen, S., Thiele, M., Juel, H. B., Hansen, Torben & Krag, A., 2022, In: Journal of Hepatology. 77, 6, p. 1720-1721 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  66. Published

    Extreme duration exercise affects old and younger men differently

    Frandsen, J., Sahl, R. E., Rømer, T., Thunestvedt Hansen, M., Nielsen, A. B., Lie-Olesen, M. M., Rasmusen, H. K., Søgaard, D., Ingersen, A., Rosenkilde, M., Westerterp, K., Holst, J. J., Andersen, J. L., Markowski, A. R., Blachnio-Zabielska, A., Clemmensen, C., Sacchetti, M., Cataldo, A., Traina, M., Larsen, S. & 2 others, Dela, Flemming & Helge, Jørn Wulff, 2022, In: Acta Physiologica. 235, 3, e13816.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    FGF21 suppresses alcohol consumption through an amygdalo-striatal circuit

    Flippo, K. H., Trammell, Sam, Gillum, M. P., Aklan, I., Perez, M. B., Yavuz, Y., Smith, N. K., Jensen-Cody, S. O., Zhou, B., Claflin, K. E., Beierschmitt, A., Fink-Jensen, Anders, Knop, Filip Krag, Palmour, R. M., Grueter, B. A., Atasoy, D. & Potthoff, M. J., 2022, In: Cell Metabolism. 34, 2, p. 317-328.e6

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Fasting potentiates insulin-mediated glucose uptake in rested and prior-contracted rat skeletal muscle

    Kido, K., Egawa, T., Watanabe, S., Kawanaka, K., Treebak, Jonas Thue & Hayashi, T., 2022, In: American Journal of Physiology - Endocrinology and Metabolism. 322, 5, p. E425-E435

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Fiber mixture-specific effect on distal colonic fermentation and metabolic health in lean but not in prediabetic men

    Canfora, E. E., Hermes, G. D. A., Mueller, M., Bastings, J., Vaughan, E. E., van den Berg, M. A., Holst, Jens Juul, Venema, K., Zoetendal, E. G. & Blaak, E. E., 2022, In: Gut Microbes. 14, 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Fibroblast growth factor 21 is the main alcohol responsive peptide hormone in humans and individuals with alcohol use disorder exihibit increased plasma concentrations after alcohol intake

    Lanng, A., Gasbjerg, Lærke Smidt, Sucksdorff, A., Svenningsen, J., Trammell, Sam, Vilsbøll, Tina, Gillum, M. & Knop, Filip Krag, 2022, In: Journal of Hepatology. 77, S1, p. S121-S121 1 p., THU006.

    Research output: Contribution to journal › Conference abstract in journal › Research

  71. Published

    Fortifying a meal with oyster mushroom powder beneficially affects postprandial glucagon-like peptide-1, non-esterified free fatty acids and hunger sensation in adults with impaired glucose tolerance: a double-blind randomized controlled crossover trial

    Dicks, L., Jakobs, L., Sari, M., Hambitzer, R., Ludwig, N., Simon, M., Stehle, P., Stoffel-Wagner, B., Helfrich, H., Ahlborn, J., Rühl, M., Hartmann, Bolette, Holst, Jens Juul & Ellinger, S., 2022, In: European Journal of Nutrition. 61, p. 687–701

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study

    Wesolowska-Andersen, A., Brorsson, C. A., Bizzotto, R., Mari, A., Tura, A., Koivula, R., Mahajan, A., Vinuela, A., Tajes, J. F., Sharma, S., Haid, M., Prehn, C., Artati, A., Hong, M. G., Musholt, P. B., Kurbasic, A., Masi, F. D., Tsirigos, K., Pedersen, H. K., Gudmundsdottir, V. & 31 others, Thomas, Cecilia Engel, Banasik, Karina, Jennison, C., Jones, A., Kennedy, G., Bell, J., Thomas, L., Frost, G., Thomsen, H., Allin, K., Hansen, T. H., drb459, drb459, Hansen, Torben, Rutters, F., Elders, P., t'Hart, L., Bonnefond, A., Canouil, M., Brage, S., Kokkola, T., Heggie, A., McEvoy, D., Hattersley, A., McDonald, T., Teare, H., Ridderstrale, M., Walker, M., Forgie, I., Pedersen, Oluf Borbye, Brunak, Søren & IMI-DIRECT consortium, I. C., 2022, In: Cell Reports Medicine. 3, 1, 25 p., 100477.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Four weeks treatment with the GLP-1 receptor analogue liraglutide lowers liver fat and concomitantly circulating glucagon in individuals with overweight

    Svane, M. S., Johannesen, H. H., Hansen, Adam Espe, Martinussen, C., Bojsen-Møller, K. N., Hansen, M. L., Deacon, Carolyn F., Keller, S. H., Klausen, Thomas Levin, Loft, A., Kjær, Andreas, Löfgren, J., Madsbad, Sten, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: International Journal of Obesity. 46, 11, p. 2058–2062 8 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  74. Published

    From trainee to trainer: lessons Learned through implementation of a dual-catheter model in mice

    Nielsen, Thomas Svava & Treebak, Jonas Thue, 2022, In: Laboratory Animals. 56, S1, p. 105 1 p., S5C1.2.

    Research output: Contribution to journal › Conference abstract in journal › Research

  75. Published

    Fueling the fire of adipose thermogenesis

    Wolfrum, C. & Gerhart-Hines, Zach, 2022, In: Science. 375, 6586, p. 1229-1231 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    GDF15 in appetite and exercise: Essential player or coincidental bystander?

    Klein, A. B., Kleinert, Maximilian, Richter, Erik A. & Clemmensen, Christoffer, 2022, In: Endocrinology. 163, 1, p. 1-10 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  77. Published

    GIP affects hepatic fat and brown adipose tissue thermogenesis, but not white adipose tissue transcriptome in T1D

    Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergman, N. C., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Havelund, J. F., Gorshkov, V., Kjeldsen, F., Færgeman, N. J. K., Madsen, M. R., Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 12, p. 3261–3274

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    GIP and GLP-2 together improve bone turnover in humans supporting GIPR-GLP-2R co-agonists as future osteoporosis treatment

    Gabe, M. B. N., Skov-Jeppesen, Kirsa, Gasbjerg, Lærke Smidt, Schiellerup, S. P., Martinussen, C., Gadgaard, S., Boer, G. A., Oeke, J., Pedersen, Lola Julie Torz, Veedfald, Simon, Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: Pharmacological Research. 176, 106058.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    GLP-1 - Incretin and pleiotropic hormone with pharmacotherapy potential. Increasing secretion of endogenous GLP-1 for diabetes and obesity therapy

    Holst, Jens Juul, Jepsen, Sara Lind & Modvig, Ida Marie, 2022, In: Current Opinion in Pharmacology. 63, p. 1-7 102189.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    GLP-1 effect on ß-cell function varies according to diabetes remission status after RYGB

    Shah, A., Prasad, M., Mark, V., Holst, Jens Juul & Laferrère, B., 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2081-2089

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice

    Quarta, C., Stemmer, K., Novikoff, A., Yang, B., Klingelhuber, F., Harger, A., Bakhti, M., Bastidas-Ponce, A., Baugé, E., Campbell, J. E., Capozzi, M., Clemmensen, C., Collden, G., Cota, P., Douros, J., Drucker, D. J., DuBois, B., Feuchtinger, A., Garcia-Caceres, C., Grandl, G. & 20 others, Hennuyer, N., Herzig, S., Hofmann, S. M., Knerr, P. J., Kulaj, K., Lalloyer, F., Lickert, H., Liskiewicz, A., Liskiewicz, D., Maity, G., Perez-Tilve, D., Prakash, S., Sanchez-Garrido, M. A., Zhang, Q., Staels, B., Krahmer, N., DiMarchi, R. D., Tschöp, M. H., Finan, B. & Müller, T. D., 2022, In: Nature Metabolism. 4, 8, p. 1071-1083 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Gastric Aspiration Improves Postprandial Glucose Tolerance Without Causing a Compensatory Increase in Appetite and Food Intake

    Gether, I. M., Jensen, M. M., Nexøe-Larsen, C. C., Jorsal, T., Gasbjerg, Lærke Smidt, Naver, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Obesity Surgery. 32, p. 1385–1390

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Gastrointestinal Hormones and β-Cell Function After Gastric Bypass and Sleeve Gastrectomy: A Randomized Controlled Trial (Oseberg)

    Fatima, F., Hjelmesæth, J., Birkeland, K. I., Hanne, G. L., Hertel, J. K., Svanevik, M., Sandbu, R., Småstuen, M. C., Hartmann, Bolette, Holst, Jens Juul & Hofsø, D., 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 2, p. e756-e766 11 p., dgab643.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Genetic Predictors of Change in Waist Circumference and Waist-to-Hip Ratio With Lifestyle Intervention: The Trans-NIH Consortium for Genetics of Weight Loss Response to Lifestyle Intervention

    McCaffery, J. M., Jablonski, K. A., Pan, Q., Astrup, A., Christiansen, Malene Revsbech, Corella, D., Corso, L. M. L., Florez, J. C., Franks, P. W., Gardner, C., Hansen, Torben, Kilpeläinen, Tuomas O., Knowler, W. C., Lindström, J., Saris, W. H. M., Sørensen, Thorkild I.A., Tuomilehto, J., Uusitupa, M., Wing, R. R. & Agurs-Collins, T., 2022, In: Diabetes. 71, 4, p. 669-676 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

    Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J-W., Haessler, J., Lyytikäinen, L-P., Repetto, L., Concas, M. P., van den Berg, M. E., Weiss, S., Baldassari, A. R., Bartz, T. M., Cook, J. P., Evans, D. S. & 31 others, Freudling, R., Hines, O., Isaksen, Jonas L., Lin, H., Mei, H., Moscati, A., Müller-Nurasyid, M., Nursyifa, Casia, Qian, Y., Richmond, A., Roselli, C., Ryan, K. A., Tarazona-Santos, E., Thériault, S., van Duijvenboden, S., Warren, H. R., Yao, J., Raza, D., Aeschbacher, S., Ahlberg, Gustav, Andreasen, Laura Korsholm, Ellervik, Christina, Hansen, Torben, Jackson, R. D., Lind, L., Linneberg, Allan René, Grarup, Niels, Kanters, Jørgen K., Loos, Ruth, Olesen, Morten Steen Salling & CHARGE Consortium, C. C., 2022, In: Nature Communications. 13, 1, 18 p., 5144.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Genetic analysis of dietary intake identifies new loci and functional links with metabolic traits

    Merino, J., Dashti, H. S., Sarnowski, C., Lane, J. M., Todorov, Petar Vladimirov, Udler, M. S., Song, Y., Wang, H., Kim, J., Tucker, C., Campbell, J., Tanaka, T., Chu, A. Y., Tsai, L., Pers, Tune H, Chasman, D., Rutter, M. K., Dupuis, J., Florez, J. C. & Saxena, R., 2022, In: Nature Human Behaviour. 6, p. 155-163 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Genetic studies indicate that fetal - and not maternal - insulin resistance is associated with birth weight

    Jakupovic, Hermina, García Ureña, Mario, Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2022, In: European Journal of Human Genetics. 30, Supplement 1, p. 592-593 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  88. Published

    Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes

    Vogelezang, S., Bradfield, J. P., Early Growth Genetics Consortium, Ahluwalia, T. V. S., Liu, X., Schnurr, T. M., Frithioff-Bøjsøe, C., Bønnelykke, K., Lind, M. V., Lauritzen, L., Michaelsen, K. F., Lund, M. A. V., Melbye, M., Morgen, C. S., Pedersen, O. B., Holm, J-C., Grarup, N., Hansen, T., Nohr, E. A., Bisgaard, H. & 3 others, Grant, S. F. A., Felix, J. F. & Jaddoe, V. W. V., 2022, In: BMC Medical Genomics. 15, 16 p., 124.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

    Wang, Z., Emmerich, A., Pillon, N. J., Moore, T., Hemerich, D., Cornelis, M. C., Mazzaferro, E., Broos, S., Ahluwalia, T. S., Bartz, T. M., Bentley, A. R., Bielak, L. F., Chong, M., Chu, A. Y., Berry, D., Dorajoo, R., Dueker, N. D., Kasbohm, E., Feenstra, B., Feitosa, M. F. & 32 others, Gieger, C., Graff, M., Hall, L. M., Haller, T., Hartwig, F. P., Hillis, D. A., Huikari, V., Heard-Costa, N., Holzapfel, C., Jackson, A. U., Johansson, A., Jorgensen, A. M., Kaakinen, M. A., Karlsson, R., Kerr, K. F., Kim, B., Koolhaas, C. M., Kutalik, Z., Pacolet, A., Zhao, J., Balslev-Harder, M. N., Grarup, Niels, Linneberg, Allan René, Hansen, Torben, Melbye, M., Pedersen, Oluf Borbye, Pers, Tune H, Sørensen, Thorkild I.A., Zierath, Juleen R, Kilpeläinen, Tuomas O., Loos, Ruth & LifeLines Cohort Study, L. C. S., 2022, In: Nature Genetics. 54, p. 1332–1344 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes

    Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K., Grove, J., Albiñana, C., Geller, F., Bjurström, C. F., Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V., Erikstrup, C., Westergaard, D., Nielsen, K. R. & 19 others, Sørensen, E., Bruun, M. T., Liu, X., Hjalgrim, Henrik, Pers, Tune H, Mortensen, P. B., Mors, O., Nordentoft, Merete, Dreier, J. W., Børglum, A. D., Christensen, J., Hougaard, D. M., Buil, A., Hviid, Anders Peter, Melbye, M., Ullum, H., Berkovic, S. F., Werge, Thomas & Feenstra, B., 2022, In: Brain. 145, 2, p. 555–568

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB

    Eliasen, A. U., Pedersen, C. E. T., Rasmussen, M. A., Wang, N., Soverini, M., Fritz, A., Stokholm, J., Chawes, B. L., Morin, A., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Mortensen, P. B., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, M. & 14 others, Børglum, A. D., Werge, Thomas, Agerbo, E., Söderhall, C., Altman, M. C., Thysen, A. H., McKennan, C. G., Brix, Susanne, Gern, J. E., Ober, C., Ahluwalia, Tarun Veer Singh, Bisgaard, H., Pedersen, A. G. & Bønnelykke, Klaus, 2022, In: Journal of Allergy and Clinical Immunology. 150, 3, p. 622-630

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Genomics and phenomics of body mass index reveals a complex disease network

    Huang, J., Huffman, J. E., Huang, Y., Do Valle, Í., Assimes, T. L., Raghavan, S., Voight, B. F., Liu, C., Barabási, A. L., Huang, R. D. L., Hui, Q., Nguyen, X. M. T., Ho, Y. L., Djousse, L., Lynch, J. A., Vujkovic, M., Tcheandjieu, C., Tang, H., Damrauer, S. M., Reaven, P. D. & 19 others, Miller, D., Phillips, L. S., Ng, M. C. Y., Graff, M., Haiman, C. A., Loos, Ruth, North, K. E., Yengo, L., Smith, G. D., Saleheen, D., Gaziano, J. M., Rader, D. J., Tsao, P. S., Cho, K., Chang, K. M., Wilson, P. W. F., Sun, Y. V., O’Donnell, C. J. & VA Million Veteran Program, V. M. V. P., 2022, In: Nature Communications. 13, 1, 10 p., 7973.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease

    Zhou, W., Kanai, M., Wu, K. H. H., Rasheed, H., Tsuo, K., Hirbo, J. B., Wang, Y., Bhattacharya, A., Zhao, H., Namba, S., Surakka, I., Wolford, B. N., Lo Faro, V., Lopera-Maya, E. A., Läll, K., Favé, M. J., Partanen, J. J., Chapman, S. B., Karjalainen, J., Kurki, M. & 54 others, Maasha, M., Brumpton, B. M., Chavan, S., Chen, T. T., Daya, M., Ding, Y., Feng, Y. C. A., Guare, L. A., Gignoux, C. R., Graham, S. E., Hornsby, W. E., Ingold, N., Ismail, S. I., Johnson, R., Laisk, T., Lin, K., Lv, J., Millwood, I. Y., Moreno-Grau, S., Nam, K., Palta, P., Pandit, A., Preuss, M. H., Saad, C., Setia-Verma, S., Thorsteinsdottir, U., Uzunovic, J., Verma, A., Zawistowski, M., Loos, Ruth, deCODE Genetics, D. G., Estonian Biobank, E. B., FinnGen, F., Generation Scotland, G. S., Genes & Health Research Team, G. &. H. R. T., LifeLines, L., Mass General Brigham Biobank, M. G. B. B., Michigan Genomics Initiative, M. G. I., National Biobank of Korea, N. B. O. K., Penn Medicine BioBank, P. M. B., Qatar Biobank, Q. B., The QSkin Sun and Health Study, T. Q. S. A. H. S., Taiwan Biobank, T. B., The HUNT Study, T. H. S., UCLA ATLAS Community Health Initiative, U. A. C. H. I., Uganda Genome Resource, U. G. R., UK Biobank, U. B., Biobank of the Americas, B. O. T. A., BioBank Japan Project, B. J. P., BioMe, B., BioVU, B., CanPath - Ontario Health Study, C. -. O. H. S., China Kadoorie Biobank Collaborative Group, C. K. B. C. G. & Colorado Center for Personalized Medicine, C. C. F. P. M., 2022, In: Cell Genomics. 2, 10, 20 p., 100192.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Glucagon Clearance is Preserved in Type 2 Diabetes

    Grøndahl, M. F. G., Lund, A., Bagger, J. I., Petersen, Tonny Studsgaard, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Diabetes. 71, 1, db210024.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Glucagon and other proglucagon-derived peptides in the pathogenesis of obesity

    Holst, Jens Juul, 2022, In: Frontiers in Nutrition. 9, 8 p., 964406.

    Research output: Contribution to journal › Review › Research › peer-review

  96. Published

    Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice

    Galsgaard, Katrine Douglas, Elmelund, E., Johansen, C. D., Billeschou, Anna, Kizilkaya, Hüsün Sheyma, Ceutz, F., Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Winther-Sørensen, Marie, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Rosenkilde, Mette, Ørskov, Cathrine, Christoffersen, Christina, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Molecular Metabolism. 66, 14 p., 101639.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Glucagon-like peptide-1 (GLP-1): are its roles as endogenous hormone and therapeutic wizard congruent?

    Holst, Jens Juul, 2022, In: Journal of Internal Medicine. 291, 5, p. 557-573

    Research output: Contribution to journal › Review › Research › peer-review

  98. Published

    Glucose- and Bile Acid-Stimulated Secretion of Gut Hormones in the Isolated Perfused Intestine Is Not Impaired in Diet-Induced Obese Mice

    Dal, Jenna Elizabeth Hunt, Holst, Jens Juul & Jepsen, Sara Lind, 2022, In: Frontiers in Endocrinology. 13, 10 p., 884501.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function

    Cheung, R., Pizza, G., Chabosseau, P., Rolando, D., Tomas, A., Burgoyne, T., Wu, Z., Salowka, A., Thapa, A., Macklin, A., Cao, Y., Nguyen-Tu, M. S., Dickerson, M. T., Jacobson, D. A., Marchetti, P., Shapiro, J., Piemonti, L., de Koning, E., Leclerc, I., Bouzakri, K. & 4 others, Sakamoto, Kei, Smith, D. M., Rutter, G. A. & Martinez-Sanchez, A., 2022, In: Diabetes. 71, 7, p. 1525-1545 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Glucose-dependent insulinotropic polypeptide (GIP) induces lipolysis during stable basal insulin substitution and hyperglycemia in men with type 1 diabetes: a randomized, double-blind, placebo-controlled, crossover clinical trial

    Heimburger, S. M., Nielsen, C. N., Calanna, S., Holst, Jens Juul, Vilsbøll, Tina, Knop, Filip Krag & Christensen, Mikkel Bring, 2022, In: Diabetes, Obesity and Metabolism. 24, 1, p. 142-147

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Glucose-dependent insulinotropic polypeptide receptor antagonist treatment causes a reduction in weight gain in ovariectomised high fat diet-fed mice

    Boer, G. A., Dal, Jenna Elizabeth Hunt, Gabe, M. B. N., Windeløv, Johanne Agerlin, Sparre-Ulrich, A. H., Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4486-4499

    Research output: Contribution to journal › Journal article › Research › peer-review

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