- 2022
- Published
Prolonged lipopolysaccharide-induced illness elevates glucagon-like peptide-1 and suppresses peptide YY: A human-randomized cross-over trial
Brodersen, K., Mose, M., Ramer Mikkelsen, U., Jørgensen, J. O. L., Festersen Nielsen, M., Møller, N., Wegeberg, A., Brock, C., Hartmann, Bolette, Holst, Jens Juul & Rittig, N., 2022, In: Physiological Reports. 10, 18, 12 p., e15462.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism
Haghikia, A., Zimmermann, F., Schumann, P., Jasina, A., Roessler, J., Schmidt, D., Heinze, P., Kaisler, J., Nageswaran, V., Aigner, A., Ceglarek, U., Cineus, R., Hegazy, A. N., Van Der Vorst, E. P. C., Doring, Y., Strauch, C. M., Nemet, I., Tremaroli, V., Dwibedi, C., Krankel, N. & 12 others, , 2022, In: European Heart Journal. 43, 6, p. 518-533 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protocol for qPCR analysis that corrects for cDNA amplification efficiency
Damgaard, Mads Vargas & Treebak, Jonas Thue, 2022, In: STAR Protocols. 3, 3, 11 p., 101515.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protocol to characterize mitochondrial supercomplexes from mouse tissues by combining BN-PAGE and MS-based proteomics
Moreno Justicia, Roger, Gonzalez-Franquesa, A., Stocks, Ben Nicholas & Deshmukh, Atul Shahaji, 2022, In: STAR Protocols. 3, 1, 21 p., 101135.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pterostilbene Fails to Rescue Insulin Secretion and Sensitivity in Multiple Murine Models of Diabetes
Damgaard, Mads Vargas, Jepsen, Sara Lind, Ashcroft, Stephen Paul, Holst, Jens Juul & Treebak, Jonas Thue, 2022, In: Nutrients. 14, 18, 11 p., 3741.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative Phosphoproteomics of the Angiotensin AT2-Receptor Signaling Network Identifies HDAC1 (Histone-Deacetylase-1) and p53 as Mediators of Antiproliferation and Apoptosis
Peluso, A. A., Kempf, S. J., Verano-braga, T., Rodrigues-ribeiro, L., Johansen, L. E., Hansen, M. R., Kitlen, G., Haugaard, A. H., Sumners, C., Ditzel, H. J., Santos, R. A., Bader, M., Larsen, M. R. & Steckelings, U. M., 2022, In: Hypertension. 79, 11, p. 2530-2541Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma
Andreassen, C. H., Lorenzen, M., Nielsen, J. E., Kafai Yahyavi, S., Toft, Birgitte Grønkær, Ingerslev, L. R., Clemmensen, Christoffer, Rasmussen, Lene Juel, Bokemeyer, C., Juul, Anders, Jørgensen, A. & Jensen, M. B., 2022, In: British Journal of Cancer. 127, p. 408-421Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare coding variants in 35 genes associate with circulating lipid levels - A multi-ancestry analysis of 170,000 exomes
Hindy, G., Dornbos, P., Chaffin, M. D., Liu, D. J., Wang, M., Selvaraj, M. S., Zhang, D., Park, J., Aguilar-Salinas, C. A., Antonacci-Fulton, L., Ardissino, D., Arnett, D. K., Aslibekyan, S., Atzmon, G., Ballantyne, C. M., Barajas-Olmos, F., Barzilai, N., Becker, L. C., Bielak, L. F., Bis, J. C. & 33 others, , 2022, In: American Journal of Human Genetics. 109, 1, p. 81-96 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recessive Genome-wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes
O'Connor, M. J., Schroeder, P., Huerta-Chagoya, A., Cortés-Sánchez, P., Bonàs-Guarch, S., Guindo Martínez, Marta, Cole, J. B., Kaur, V., Torrents, D., Veerapen, K., Grarup, Niels, Kurki, M., Friis, Carsten, Pedersen, Oluf Borbye, Brandslund, I., Linneberg, Allan René, Hansen, Torben, Leong, A., Florez, J. C. & Mercader, J. M., 2022, In: Diabetes. 71, 3, p. 554–565Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recombinant human β-defensin 2 delivery improves smoking-induced lung neutrophilia and bacterial exacerbation
Milad, N., Pineault, M., Bouffard, G., Maranda-Robitaille, M., Lechasseur, A., Beaulieu, M. J., Aubin, S., Jensen, Benjamin Anderschou Holbech & Morissette, M. C., 2022, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 323, 1, p. L37-L47 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue
Gonzalez-Franquesa, A., Gama-Perez, P., Kulis, M., Szczepanowska, K., Dahdah, N., Moreno-Gomez, S., Latorre-Pellicer, A., Fernández-Ruiz, R., Aguilar-Mogas, A., Hoffman, A., Monelli, E., Samino, S., Miró-Blanch, J., Oemer, G., Duran, X., Sanchez-Rebordelo, E., Schneeberger, M., Obach, M., Montane, J., Castellano, G. & 27 others, , 2022, In: Redox Biology. 54, 18 p., 102353.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply - Letter to the editor - On carbohydrate restriction and health-related quality of life and cognition in type 2 diabetes
Jensen, N. J., Thomsen, M. N., Skytte, M. J., Astrup, A., Holst, Jens Juul, Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Haugaard, Steen Bendix, Krarup, T. & Rungby, Jørgen, 2022, In: Clinical Nutrition. 41, 9, p. 2061-2062 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Reply to ‘Lactate as a major myokine and exerkine’
Chow, L. S., Gerszten, R. E., Taylor, J. M., Pedersen, B. K., van Praag, H., Trappe, S., Febbraio, M. A., Galis, Z. S., Gao, Y., Haus, J. M., Lanza, I. R., Lavie, C. J., Lee, C. H., Lucia, A., Moro, C., Pandey, A., Robbins, J. M., Stanford, K. I., Thackray, A. E., Villeda, S. & 5 others, , 2022, In: Nature Reviews Endocrinology. 18, 11, p. 713 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Rhythmic history: Towards a new research agenda for the history of health and medicine
Hussey, Kristin D., 2022, In: Endeavour. 46, 4, 10 p., 100846.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response
Snieckute, Goda, Genzor Garbayo, Aitana Victoria, Vind, Anna Constance, Jordan, Laura Ryder, Stoneley, M., Chamois, S., Dreos, R., Nordgaard, C., Sass, Frederike, Blasius, Melanie, López, A. R., Brynjólfsdóttir, S. H., Andersen, Kasper Langebjerg, Willis, A. E., Frankel, Lisa, Poulsen, Steen Seier, Gatfield, D., Gerhart-Hines, Zach, Clemmensen, Christoffer & Bekker-Jensen, Simon Holst, 2022, In: Cell Metabolism. 34, 12, p. 2036-2046.e8 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of endogenous incretins in the regulation of postprandial lipoprotein metabolism
Taskinen, M., Matikainen, N., Björnson, E., Söderlund, S., Ainola, M., Hakkarainen, A., Lundbom, N., Sihlbom, C., Thorsell, A., Andersson, L., Adiels, M., Hartmann, Bolette, Deacon, Carolyn F., Holst, Jens Juul, Packard, C. J. & Borén, J., 2022, In: European Journal of Endocrinology. 187, 1, p. 75-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Safety and efficacy of liraglutide versus colesevelam for the treatment of bile acid diarrhoea: A randomised, double-blind, active-comparator, non-inferiority clinical trial
Kårhus, M. L., Brønden, A., Forman, Julie Lyng, Haaber, A., Knudsen, E., Langholz, Ebbe, Dragsted, Lars Ove, Hansen, S. H., Krakauer, M., Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2022, In: The Lancet Gastroenterology and Hepatology. 7, 10, p. 922-931 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Scale in the history of medicine
Tybjerg, Karin, 2022, In: Studies in History and Philosophy of Science. 91, p. 221-233 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Segmental reversal of the distal small intestine in a short bowel syndrome model in piglets showed detrimental effect on weight gain
Schmidt, L. H., Aa, J. S., Hartmann, Bolette, Madsen, G. I., Qvist, N. & Ellebæk, M. B., 2022, In: BMC Gastroenterology. 22, 1, 9 p., 349.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Seroprevalence and infection fatality rate of the SARS-CoV-2 Omicron variant in Denmark: A nationwide serosurveillance study
Erikstrup, C., Laksafoss, A. D., Gladov, J., Kaspersen, K. A., Mikkelsen, S., Hindhede, L., Boldsen, J. K., Jørgensen, S. W., Ethelberg, S., Holm, D. K., Bruun, M. T., Nissen, J., Schwinn, M., Brodersen, T., Mikkelsen, C., Sækmose, S. G., Sørensen, E., Harritshøj, L. H., Aagaard, B., Dinh, K. M. & 7 others, , 2022, In: The Lancet Regional Health - Europe. 21, 100479.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serotonin G Protein-Coupled Receptor-Based Biosensing Modalities in Yeast
Lengger, B., Hoch-Schneider, E. E., Jensen, C. N., Jakočiū Nas, T., Petersen, A. A., Frimurer, Thomas Michael, Jensen, E. D. & Jensen, M. K., 2022, In: ACS Sensors. 7, 5, p. 1323-1335Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Blokland, G. A. M., Grove, J., Chen, C. Y., Cotsapas, C., Tobet, S., Handa, R., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M. & 35 others, , 2022, In: Biological Psychiatry. 91, 1, p. 107-117Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-cell transcriptome and cell type-specific molecular pathways of human non-alcoholic steatohepatitis
Fred, Rikard Göran, Steen Pedersen, J., Thompson, J. J., Lee, J., Timshel, P. N., Stender, S., Rygg, M. O., Gluud, Lise Lotte, Bjerregaard Kristiansen, V., Bendtsen, Flemming, Hansen, Torben & Pers, Tune H, 2022, In: Scientific Reports. 12, 1, 13 p., 13484.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Smoking during pregnancy is associated with child overweight independent of maternal pre-pregnancy BMI and genetic predisposition to adiposity
Schnurr, T. M., Ängquist, Lars, Nohr, E. A., Hansen, Torben, Sørensen, Thorkild I.A. & Morgen, C. S., 2022, In: Scientific Reports. 12, 1, 10 p., 3135.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Smoking remains associated with education after controlling for social background and genetic factors in a study of 18 twin cohorts
Silventoinen, K., Piirtola, M., Jelenkovic, A., Sund, R., Tarnoki, A. D., Tarnoki, D. L., Medda, E., Nisticò, L., Toccaceli, V., Honda, C., Inui, F., Tomizawa, R., Watanabe, M., Sakai, N., Gatz, M., Butler, D. A., Lee, J., Lee, S. J., Sung, J., Franz, C. E. & 31 others, , 2022, In: Scientific Reports. 12, 1, 9 p., 13148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Staying strong during hibernation
Sommer, F. & Bäckhed, F., 2022, In: Science. 375, 6579, p. 376-377 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stool energy density is positively correlated to intestinal transit time and related to microbial enterotypes
Boekhorst, J., Venlet, N., Procházková, Nicola, Hansen, M. L., Lieberoth, C. B., Bahl, M. I., Lauritzen, Lotte, Pedersen, Oluf Borbye, Licht, T. R., Kleerebezem, M. & Roager, Henrik Munch, 2022, In: Microbiome. 10, 10 p., 223.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies in Rats of Combined Muscle and Liver Perfusion and of Muscle Extract Indicate That Contractions Release a Muscle Hormone Directly Enhancing Hepatic Glycogenolysis
Han, X. X., Holst, Jens Juul & Galbo, Henrik, 2022, In: Journal of Personalized Medicine. 12, 5, 12 p., 837.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Successful treatment of psoriasis with adalimumab induced no changes in the gut microbiota
Todberg, T., Egeberg, Alexander, Zachariae, Claus, Sørensen, N., Pedersen, Oluf Borbye & Skov, Lone, 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 6, p. e464-e467 4 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Sucrose synthase activity is not required for cellulose biosynthesis in Arabidopsis
Wang, W., Viljamaa, S., Hodek, O., Moritz, Thomas & Niittylä, T., 2022, In: Plant Journal. 110, 5, p. 1493-1497Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustained inhibition of NPY/AgRP neuronal activity by FGF1
Hwang, E., Scarlett, J. M., Baquero, A. F., Bennett, C. M., Dong, Y., Chau, D., Brown, Jenny, Mercer, A. J., Meek, T. H., Grove, K. L., Phan, B. A. N., Morton, G. J., Williams, K. W. & Schwartz, M. W., 2022, In: JCI insight. 7, 17, 11 p., e160891.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
THERAPY OF ENDOCRINE DISEASE: Amylin and calcitonin - physiology and pharmacology
Mathiesen, D. S., Lund, A., Holst, Jens Juul, Knop, Filip Krag, Lutz, T. A. & Bagger, J. I., 2022, In: European Journal of Endocrinology. 186, 6, p. R93-R111Research output: Contribution to journal › Review › Research › peer-review
- Published
TOP-LD: A tool to explore linkage disequilibrium with TOPMed whole-genome sequence data
Huang, L., Rosen, J. D., Sun, Q., Chen, J., Wheeler, M. M., Zhou, Y., Min, Y. I., Kooperberg, C., Conomos, M. P., Stilp, A. M., Rich, S. S., Rotter, J. I., Manichaikul, A., Loos, R. J. F., Kenny, E. E., Blackwell, T. W., Smith, A. V., Jun, G., Sedlazeck, F. J., Metcalf, G. & 6 others, , 2022, In: American Journal of Human Genetics. 109, 6, p. 1175-1181 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Accuracy of Hemoglobin A1c and Fructosamine Evaluated by Long-Term Continuous Glucose Monitoring in Patients with Type 2 Diabetes Undergoing Hemodialysis
Bomholt, T., Rix, M., Almdal, Thomas Peter, Knop, Filip Krag, Rosthøj, Susanne, Heinrich, N. S., Jørgensen, M. B., Larsson, A., Hilsted, Linda, Feldt-Rasmussen, Bo & Hornum, Mads, 2022, In: Blood Purification. 51, p. 608–616 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Arg82Cys Polymorphism of the Protein Nepmucin Implies a Role in HDL Metabolism
Metz, Sophia, Krarup, N. T., Bryrup, T., Støy, J., Andersson, E. A., Christoffersen, Christina, Neville, M. J., Christiansen, Malene Revsbech, Jonsson, Anna Elisabet, Witte, D. R., Kampmann, U., Nielsen, L. B., Jørgensen, Niklas Rye, Karpe, F., Grarup, Niels, Pedersen, Oluf Borbye, Kilpeläinen, Tuomas O. & Hansen, Torben, 2022, In: Journal of the Endocrine Society. 6, 5, 10 p., bvac034.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance
Klein, A. B., Nicolaisen, T. S., Johann, K., Fritzen, Andreas Mæchel, Mathiesen, C. V., Gil, Cláudia, Pilmark, N. S., Karstoft, Kristian, Blond, Martin Bæk, Quist, Jonas Salling, Seeley, R. J., Færch, K., Lund, Jens, Kleinert, Maximilian & Clemmensen, Christoffer, 2022, In: Cell Reports. 40, 8, 111258.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Glucagon Receptor Antagonist LY2409021 has No Effect on Postprandial Glucose in Type 2 Diabetes
Hædersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Forman, Julie Lyng, van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 186, 2, p. 207-221 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Greenland population health survey 2018 - methods of a prospective study of risk factors for lifestyle related diseases and social determinants of health amongst Inuit
Bjerregaard, P., Larsen, C. V. L., Olesen, I., Ottendahl, C. B., Backer, Vibeke, Senftleber, N., Christensen, M. M. B., Larsen, T. J., Byberg, S., Hansen, Torben & Jørgensen, M. E., 2022, In: International Journal of Circumpolar Health. 81, 1, 11 p., 2090067.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Liver-Alpha Cell Axis in Health and in Disease
Richter, Michael Martin, Galsgaard, Katrine Douglas, Elmelund, E., Knop, Filip Krag, Suppli, M. P., Holst, Jens Juul, Winther-Sørensen, Marie, Kjeldsen, Sasha Alexandra Sampson & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Diabetes. 71, +, p. 1852–1861Research output: Contribution to journal › Review › Research › peer-review
- Published
The Location of Missense Variants in the Human GIP Gene Is Indicative for Natural Selection
Lindquist, Peter, Gasbjerg, Lærke Smidt, Mokrosinski, J., Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, Mette, 2022, In: Frontiers in Endocrinology. 13, 14 p., 891586.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Many Faces of Gaia’s Response-ability: A Field Trip to the Critical Zones Digital Platform
Formosinho, Joana, 2022, In: Museums Worlds: Advances in Research. 10, p. 181-192 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Metabolic Role and Therapeutic Potential of the Microbiome
Olofsson, L. E. & Backhed, F., 2022, In: Endocrine Reviews. 43, p. 907-926Research output: Contribution to journal › Review › Research › peer-review
- Published
The Role of D-allulose and Erythritol on the Activity of the Gut Sweet Taste Receptor and Gastrointestinal Satiation Hormone Release in Humans: A Randomized, Controlled Trial
Teysseire, F., Bordier, V., Budzinska, A., Weltens, N., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Beglinger, C., Van Oudenhove, L., Wölnerhanssen, B. K. & Meyer-Gerspach, A. C., 2022, In: Journal of Nutrition. 152, 5, p. 1228–1238,Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion
Hjørne, A. P., Modvig, Ida Marie & Holst, Jens Juul, 2022, In: Metabolites. 12, 5, 15 p., 420.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Value of Rare Genetic Variation in the Prediction of Common Obesity in European Ancestry Populations
Wang, Z., Choi, S. W., Chami, N., Boerwinkle, E., Fornage, M., Redline, S., Bis, J. C., Brody, J. A., Psaty, B. M., Kim, W., McDonald, M. L. N., Regan, E. A., Silverman, E. K., Liu, C. T., Vasan, R. S., Kalyani, R. R., Mathias, R. A., Yanek, L. R., Arnett, D. K., Justice, A. E. & 21 others, , 2022, In: Frontiers in Endocrinology. 13, 12 p., 863893.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The developing airway and gut microbiota in early life is influenced by age of older siblings
Christensen, E. D., Hjelmsø, M. H., Thorsen, Jonathan Jan Ilve, Shah, S., Redgwell, T., Poulsen, Christina Egeø, Trivedi, Urvish, Russel, J., Gupta, S., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Sørensen, Søren Johannes, Rasmussen, Morten Arendt, Bisgaard, H. & Stokholm, Jakob, 2022, In: Microbiome. 10, 15 p., 106.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The developing infant gut microbiome: A strain-level view
Enav, H., Bäckhed, F. & Ley, R. E., 2022, In: Cell Host and Microbe. 30, 5, p. 627-638 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The effect of curcumin on hepatic fat content in individuals with obesity
Hellmann, P. H., Bagger, J. I., Carlander, K. R., Forman, Julie Lyng, Chabanova, E., Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2192-2202 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of gluten in adolescents and young adults with gastrointestinal symptoms: A blinded randomised cross-over trial
Crawley, C., Savino, N., Halby, C., Sander, S. D., Nybo Andersen, Anne-Marie, Arumugam, Mani, Murray, J., Christensen, R. & Husby, S., 2022, In: Alimentary Pharmacology and Therapeutics, Supplement. 55, 9, p. 1116-1127 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of laparoscopic Roux-en-Y gastric bypass and one-anastomosis gastric bypass on glycemic control and remission of type 2 diabetes mellitus: study protocol for a multi-center randomized controlled trial (the DIABAR-trial)
van Rijswijk, A., van Olst, N., Meijnikman, A. S., Acherman, Y. I. Z., Bruin, S. C., van de Laar, A. W., van Olden, C. C., Aydin, O., Borger, H., Beuers, U. H. W., Herrema, H., Verheij, J., Apers, J. A., Bäckhed, F., Gerdes, V. E. A., Nieuwdorp, M. & de Brauw, L. M., 2022, In: Trials. 23, 12 p., 900.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The energy balance model of obesity: beyond calories in, calories out
Hall, K. D., Farooqi, I. S., Friedman, J. M., Klein, S., Loos, Ruth, Mangelsdorf, D. J., O'Rahilly, S., Ravussin, E., Redman, L. M., Ryan, D. H., Speakman, J. R. & Tobias, D. K., 2022, In: American Journal of Clinical Nutrition. 115, 5, p. 1243-1254 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glucagon receptor antagonist LY2409021 does not affect gastrointestinal-mediated glucose disposal or the incretin effect in individuals with and without type 2 diabetes
Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., Forman, Julie Lyng, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 187, 4, p. 507-518 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The human batokine EPDR1 regulates β-cell metabolism and function
Cataldo Bascunan, Luis Rodrigo, Gao, Q., Argemi Muntadas, Lidia, Hodek, O., Cowan, E., Hladkou, S., Gheibi, S., Spegel, P., Prasad, R. B., Eliasson, L., Schéele, Camilla Charlotte Nielsen, Fex, M., Mulder, H. & Moritz, Thomas, 2022, In: Molecular Metabolism. 66, 14 p., 101629.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of anorexia nervosa and BMI polygenic risk on childhood growth: A 20-year longitudinal population-based study
Abdulkadir, M., Hübel, C., Herle, M., Loos, Ruth, Breen, G., Bulik, C. M. & Micali, N., 2022, In: American Journal of Human Genetics. 109, 7, p. 1242-1254 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The incretin/glucagon system as a target for pharmacotherapy of obesity
Del Prato, S., Gallwitz, B., Holst, Jens Juul & Meier, J. J., 2022, In: Obesity Reviews. 23, 2, 13 p., e13372.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The new donor vigilance system in Denmark reveals regional differences in adverse reactions supposedly caused by variation in the registration
Mikkelsen, Christina, Paarup, H. M., Bruun, M. T., Pedersen, L. Ø., Hasslund, S., Larsen, R., Aagaard, B. & Sørensen, B. S., 2022, In: Vox Sanguinis. 117, 3, p. 321-327Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids
Desjardins, E. M., Smith, B. K., Day, E. A., Ducommun, S., Sanders, M. J., Nederveen, J. P., Ford, R. J., Pinkosky, S. L., Townsend, L. K., Gutgesell, R. M., Lu, R., Sakamoto, Kei & Steinberg, G. R., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 48, 8 p., e2119824119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The physiology of experimental overfeeding in animals
Ranea-Robles, Pablo, Lund, Jens & Clemmensen, Christoffer, 2022, In: Molecular Metabolism. 64, 15 p., 101573.Research output: Contribution to journal › Review › Research › peer-review
- Published
The physiology of obesity: from mechanisms to medicine (M2M). Part one
Lewis, J. E. & Aldiss, Peter Stuart Jacob, 2022, In: Journal of Physiology. 600, 4, p. 697-698 2 p.Research output: Contribution to journal › Editorial › Research
- Published
The physiology of obesity; from mechanisms to medicine. Part two
Aldiss, Peter Stuart Jacob & Lewis, J. E., 2022, In: Journal of Physiology. 600, 5, p. 999-1000 2 p.Research output: Contribution to journal › Editorial › Research
- Published
The proteomic profile of the human myotendinous junction
Karlsen, Anders, Gonzalez-Franquesa, A., Jakobsen, J. R., Krogsgaard, Michael R., Koch, M., Kjær, Michael, Schiaffino, S., Mackey, Abigail & Deshmukh, Atul Shahaji, 2022, In: iScience. 25, 2, 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling
Segref, A., Vakkayil, K. L., Padvitski, T., Li, Q., Kroef, V., Lormann, J., Körner, L., Finger, Fabian Michael & Hoppe, T., 2022, In: Nature Communications. 13, 1, 17 p., 5874.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thyrotropin-releasing hormone induces Ca2+ increase in a subset of vagal nodose ganglion neurons
Mamedova, Esmira, Dmytriyeva, O. & Rekling, Jens Christian, 2022, In: Neuropeptides. 94, 9 p., 102261.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tolerable Duration of Warm Ischaemia After Circulatory Death Is Safe For At Least One Hour in Porcine Lungs: Functional Assessment with Ex Vivo Lung Perfusion
Hebsgaard, M. M. B., Kissow, Hannelouise, Lilleør, N. B., Lorenzen, U. S., Chemtob, R. A., Møller-Sørensen, H., Olsen, P. S. & Møller, Christian H., 2022, In: Heart Surgery Forum. 25, 1, p. E48-E52 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transforming growth factor β1 impairs the transcriptomic response to contraction in myotubes from women with polycystic ovary syndrome
McIlvenna, L. C., Altıntaş, Ali, Patten, R. K., McAinch, A. J., Rodgers, R. J., Stepto, N. K., Barrès, Romain & Moreno-Asso, A., 2022, In: The Journal of Physiology. 600, 14, p. 3313-3330Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 2 diabetes classification: a data-driven cluster study of the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort
Christensen, D. H., Nicolaisen, S. K., Ahlqvist, E., Stidsen, J. V., Nielsen, J. S., Hojlund, K., Olsen, M. H., García-Calzón, S., Ling, C., Rungby, Jørgen, Brandslund, I., Vestergaard, P., Jessen, N., Hansen, Torben, Brøns, C., Beck-Nielsen, H., Sørensen, H. T., Thomsen, R. W. & Vaag, Allan, 2022, In: B M J Open Diabetes Research & Care. 10, 2, 12 p., e002731.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 2 diabetes is associated with increased circulating levels of 3-hydroxydecanoate activating GPR84 and neutrophil migration
Mikkelsen, R. B., Arora, Tulika, Trošt, K., Dmytriyeva, O., Jensen, Sune K. , Meijnikman, A. S., Olofsson, L. E., Lappa, D., Aydin, Ö., Nielsen, J., Gerdes, V., Moritz, Thomas, van de Laar, A., de Brauw, M., Nieuwdorp, M., Hjorth, Siv Annegrethe, Schwartz, Thue W. & Bäckhed, F., 2022, In: iScience. 25, 12, 29 p., 105683.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vagal afferent cholecystokinin receptor activation is required for glucagon-like peptide-1–induced satiation
Vana, V., Lærke, M. K., Rehfeld, Jens Frederik, Arnold, M., Dmytriyeva, O., Langhans, W., Schwartz, Thue W. & Hansen, Harald S., 2022, In: Diabetes, Obesity and Metabolism. 24, 2, p. 268-280Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin D Supplementation Improves Fasting Insulin Levels and HDL Cholesterol in Infertile Men
Holt, R., Petersen, Jørgen Holm, Dinsdale, E., Knop, Filip Krag, Juul, Anders, Jørgensen, N. & Jensen, M. B., 2022, In: Journal of Clinical Endocrinology & Metabolism. 107, 1, p. 98-108Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial
Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2022, In: Frontiers in Nutrition. 9, 14 p., 933118.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Weight-loss induced by carbohydrate restriction does not negatively affect health-related quality of life and cognition in people with type 2 diabetes: A randomised controlled trial
Jensen, N. J., Wodschow, H. Z., Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Haugaard, Steen Bendix, Krarup, T., Rungby, Jørgen & Thomsen, M. N., 2022, In: Clinical Nutrition. 41, 7, p. 1605-1612 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole genome sequence analysis of blood lipid levels in >66,000 individuals
Selvaraj, M. S., Li, X., Li, Z., Pampana, A., Zhang, D. Y., Park, J., Aslibekyan, S., Bis, J. C., Brody, J. A., Cade, B. E., Chuang, L. M., Chung, R. H., Curran, J. E., de las Fuentes, L., de Vries, P. S., Duggirala, R., Freedman, B. I., Graff, M., Guo, X., Heard-Costa, N. & 27 others, , 2022, In: Nature Communications. 13, 18 p., 5995.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program
Wheeler, M. M., Stilp, A. M., Rao, S., Halldórsson, B. V., Beyter, D., Wen, J., Mihkaylova, A. V., McHugh, C. P., Lane, J., Jiang, M. Z., Raffield, L. M., Jun, G., Sedlazeck, F. J., Metcalf, G., Yao, Y., Bis, J. B., Chami, N., de Vries, P. S., Desai, P., Floyd, J. S. & 39 others, , 2022, In: Nature Communications. 13, 18 p., 7592.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
With obesity becoming the new normal, what should we do? Volume II
Tziomalos, K., Kilpeläinen, Tuomas O. & Samaras, K., 2022, In: Frontiers in Endocrinology. 13, 3 p., 1119910.Research output: Contribution to journal › Editorial › Research
- Published
Worsening Postural Tachycardia Syndrome Is Associated With Increased Glucose-Dependent Insulinotropic Polypeptide Secretion
Breier, N. C., Paranjape, S. Y., Scudder, S., Mehr, S. E., Diedrich, A., Flynn, C. R., Okamoto, L. E., Hartmann, Bolette, Gasbjerg, Lærke Smidt & Shibao, C. A., 2022, In: Hypertension. 79, 5, p. e89-e99Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle
Nordgaard, C., Vind, A. C., Stonadge, A., Kjøbsted, R., Snieckute, G., Antas, P., Blasius, M., Reinert, M. S., Del Val, A. M., Bekker-Jensen, D. B., Haahr, P., Miroshnikova, Y. A., Mazouzi, A., Falk, S., Perrier-Groult, E., Tiedje, C., Li, X., Jakobsen, J. R., Jørgensen, N. O., Wojtaszewski, J. & 12 others, , 2022, In: E M B O Journal. 41, 17, 19 p., e111650.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Zeitgebers of skeletal muscle and implications for metabolic health
Gabriel, B. M. & Zierath, Juleen R, 2022, In: Journal of Physiology. 600, 5, p. 1027-1036Research output: Contribution to journal › Journal article › Research › peer-review
- Published
microRNA-based signatures obtained from endometrial fluid identify implantative endometrium
Ibañez-Perez, J., Díaz-Nuñez, M., Clos-García, M., Lainz, L., Iglesias, M., Díez-Zapirain, M., Rabanal, A., Bárcena, L., González, M., Lozano, J. J., Marigorta, U. M., González, E., Royo, F., Aransay, A. M., Subiran, N., Matorras, R. & Falcón-Pérez, J. M., 2022, In: Human Reproduction. 37, 10, p. 2375-2391 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Editorial: Proglucagon-Derived Peptides
Flatt, P. R., Knop, Filip Krag & Tarasov, A. I., Nov 2021, In: Frontiers in Endocrinology. 12, 776871.Research output: Contribution to journal › Editorial › Research
- Published
Museum as Academy: Research Practices at Copenhagen’s Medical Museion
Arnold, Ken, Bencard, Adam, Tybjerg, Karin & Whiteley, Louise, 24 Sep 2021, In: The Garage Journal: Studies in Art, Museums & Culture. 3, p. 52 81 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Authors’ Reply to Letter to the Editor: Continued improvement to genetic diversity indicator for CBD
Laikre, L., Hohenlohe, P. A., Allendorf, F. W., Bertola, L. D., Breed, M. F., Bruford, M. W., Funk, W. C., Gajardo, G., González-Rodríguez, A., Grueber, C. E., Hedrick, P. W., Heuertz, M., Hunter, M. E., Johannesson, K., Liggins, L., MacDonald, A. J., Mergeay, J., Moharrek, F., O’Brien, D., Ogden, R. & 11 others, , Aug 2021, In: Conservation Genetics. 22, 4, p. 533-536 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Hepatic microbiome in healthy lean and obese humans
Suppli, M. P., Bagger, J. I., Lelouvier, B., Broha, A., Demant, M., Kønig, M. J., Strandberg, C., Lund, A., Vilsbøll, Tina & Knop, Filip Krag, Aug 2021, In: JHEP Reports. 3, 4, 100299.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined
Lundgren, J. R., Janus, C., Jensen, Simon Birk Kjær, Juhl, C. R., Olsen, L. M., Christensen, R. M., Svane, M. S., Bandholm, Thomas Quaade, Bojsen-Møller, K. N., Blond, Martin Bæk, Jensen, Jens-Erik Beck, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 6 May 2021, In: New England Journal of Medicine. 384, p. 1719-1730 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
Sass, Frederike, Schlein, C., Jaeckstein, M. Y., Pertzborn, P., Schweizer, M., Schinke, T., Ballabio, A., Scheja, L., Heeren, J. & Fischer, A. W., 1 May 2021, In: Molecular Metabolism. 47, 19 p., 101173.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal obesity and metabolic disorders associate with congenital heart defects in the offspring: A systematic review
Hedermann, G., Hedley, P. L., Thagaard, I. N., Krebs, Lone, Ekelund, Charlotte Kvist, Sørensen, Thorkild I.A. & Christiansen, M., May 2021, In: PLoS ONE. 16, 5 , 22 p., e0252343.Research output: Contribution to journal › Review › Research › peer-review
- Published
Pancreatic polypeptide: A potential biomarker of glucose-dependent insulinotropic polypeptide receptor activation in vivo
Veedfald, Simon, Bergmann, N. C., Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Jens Juul & Knop, Filip Krag, May 2021, In: Diabetic Medicine Online. 38, 8, e14592.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Effects of endogenous GIP in patients with type 2 diabetes
Stensen, S., Gasbjerg, Lærke Smidt, Krogh, L. L., Skov-Jeppesen, Kirsa, wbf943, wbf943, Jensen, M. H., Dela, Flemming, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, Mikkel Bring & Knop, Filip Krag, Apr 2021, In: European Journal of Endocrinology. 185, 1, p. 33-45Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic effects of one-week binge drinking and fast food intake during Roskilde Festival in young healthy male adults
Demant, Mia Grønlund, Suppli, M. P., Foghsgaard, S., Gether, L., Grøndahl, M. F. G., Dalsgaard, N. B., Bergmann, S. S., Lanng, A. R., Gasbjerg, Lærke Smidt, Thomasen, M., Bagger, J. I., Strandberg, C., Kønig, M. J., Grønbæk, H., Becker, U., Holst, Jens Juul, Knop, J., Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, Apr 2021, In: European Journal of Endocrinology. 185, 1, p. 23-32Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structured supervised exercise training or motivational counselling during pregnancy on physical activity level and health of mother and offspring: FitMum study protocol
Roland, Caroline Borup, Knudsen, S. D. P., Alomairah, S. A., Jessen, Anne Dsane, Bendix, J., Clausen, Tine Dalsgaard, Mølsted, Stig, Jensen, Andreas Kryger, Teilmann, Grete Katrine, Jespersen, Astrid Pernille, Larsen, J. E., van Hall, Gerrit, Andersen, E., Barrès, Romain, Mortensen, Ole Hartvig, Maindal, H. T., Tarnow, L., Løkkegaard, Ellen Christine Leth & Stallknecht, Bente Merete, 19 Mar 2021, In: BMJ Open. 11, 3, 11 p., e043671.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Editorial: non-selective beta blockers—in and out of circulation
Kimer, N., Mortensen, C. & Hobolth, L., Mar 2021, In: Alimentary Pharmacology and Therapeutics. 53, 5, p. 632-633 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Too narrow and too broad: Differentiating late-onset dementiafrom its historical entanglement with Alzheimer’s disease
Moseholm, Kristine Frøsig, Tybjerg, Karin, Jensen, Majken Karoline & Westendorp, Rudi GJ, Mar 2021, In: Aging Brain. 1, 100010.Research output: Contribution to journal › Journal article › Research
- Published
Venous thromboembolism after fast-track elective revision hip and knee arthroplasty – A multicentre cohort study of 2814 unselected consecutive procedures
Lundbeck Foundation Centre for Fast-track Hip and Knee Arthroplasty collaborating group, L. F. C. F. F. H. A. K. A. C. G., Mar 2021, In: Thrombosis Research. 199, p. 101-105 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Medicinske museer – museet som trickster
Tybjerg, Karin, 15 Jan 2021, Museologi mellem fagene. Skytte Jakobsen, L., Hejlskov Larsen, A. & Nørskov, V. (eds.). 1 ed. Aarhus: Aarhus Universitetsforlag, p. 383-406 23 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Skeletal muscle
Markby, G. R. & Sakamoto, Kei, 1 Jan 2021, Autophagy in Health and Disease. Elsevier, p. 213-225 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
"Visceral Consciousness": The Gut-Brain Axis in Victorian Sleep and Sleeplessness in Britain and America, 1850-1914
Hussey, Kristin D., 2021, In: Bulletin of the History of Medicine. 95, 3, p. 350-378Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity
Basse, A. L., Agerholm, M., Farup, J., Dalbram, E., Nielsen, J., Ørtenblad, N., Altıntaş, A., Ehrlich, A. M., Krag, T., Bruzzone, S., Dall, M., de Guia, R. M., Jensen, J. B., Møller, A. B., Karlsen, A., Kjær, M., Barrès, R., Vissing, J., Larsen, S., Jessen, N. & 1 others, , 2021, In: Molecular Metabolism. 53, 101271.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts
Ni, G., Zeng, J., Revez, J. A., Wang, Y., Zheng, Z., Ge, T., Restuadi, R., Kiewa, J., Nyholt, D. R., Coleman, J. R. I., Smoller, J. W., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A. & 21 others, , 2021, In: Biological Psychiatry. 90, 9, p. 611-620Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Danish population-based case series of patients with liver cirrhosis and coronavirus disease 2019
Attauabi, M., Burisch, J., Bendtsen, Flemming & Kimer, N., 2021, In: Scandinavian Journal of Gastroenterology. 56, 4, p. 453-457Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Gut-Intrinsic Melanocortin Signaling Complex Augments L-Cell Secretion in Humans
Sun, E. W., Iepsen, E. W., Pezos, N., Lumsden, A. L., Martin, A. M., Schober, G., Isaacs, N. J., Rayner, C. K., Nguyen, N. Q., de Fontgalland, D., Rabbitt, P., Hollington, P., Wattchow, D. A., Hansen, Torben, Holm, Jens-Christian, Liou, A. P., Jackson, V. M., Torekov, Signe Sørensen, Young, R. L. & Keating, D. J., 2021, In: Gastroenterology. 161, 2, p. 536-547.e2 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Pharmacological and Clinical Overview of Oral Semaglutide for the Treatment of Type 2 Diabetes
Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Drugs. 81, p. 1003-1030 28 p.Research output: Contribution to journal › Review › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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