Loos Group

  1. 2024
  2. E-pub ahead of print

    An integrative framework to prioritize genes in more than 500 loci associated with body mass index

    Hemerich, D., Svenstrup, Victor, Díez Obrero, Virginia, Preuss, M. H., Moscati, A., Hirschhorn, J. N. & Loos, Ruth, 9 May 2024, (E-pub ahead of print) In: American Journal of Human Genetics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels

    de Vries, P. S., Reventun, P., Brown, M. R., Heath, A. S., Huffman, J. E., Le, N. Q., Bebo, A., Brody, J. A., Temprano-Sagrera, G., Raffield, L. M., Ozel, A. B., Thibord, F., Jain, D., Lewis, J. P., Rodriguez, B. A. T., Pankratz, N., Taylor, K. D., Polasek, O., Chen, M. H., Yanek, L. R. & 32 others, Carrasquilla, Germán D., Marioni, R. E., Kleber, M. E., Trégouët, D. A., Yao, J., Li-Gao, R., Joshi, P. K., Trompet, S., Martinez-Perez, A., Ghanbari, M., Howard, T. E., Reiner, A. P., Arvanitis, M., Ryan, K. A., Bartz, T. M., Rudan, I., Faraday, N., Linneberg, Allan René, Ekunwe, L., Davies, G., Delgado, G. E., Hansen, Torben, Chen, W. M., Jackson, Rebecca, Liu, Y., Loos, Ruth, Rao, Divya, Wang, L., Nielsen, J. B., Kilpeläinen, Tuomas O., Trans-Omics for Precision Medicine (TOPMed) program, T. F. P. M. (. P. & the INVENT consortium, T. I. C., 2 May 2024, In: Blood. 143, 18, p. 1845-1855 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A genomic mutational constraint map using variation in 76,156 human genomes

    Chen, S., Francioli, L. C., Goodrich, J. K., Collins, R. L., Kanai, M., Wang, Q., Alföldi, J., Watts, N. A., Vittal, C., Gauthier, L. D., Poterba, T., Wilson, M. W., Tarasova, Y., Phu, W., Grant, R., Yohannes, M. T., Koenig, Z., Farjoun, Y., Banks, E., Donnelly, S. & 18 others, Gabriel, S., Gupta, N., Ferriera, S., Tolonen, C., Novod, S., Bergelson, L., Roazen, D., Ruano-Rubio, V., Covarrubias, M., Llanwarne, C., Petrillo, N., Wade, G., Jeandet, T., Munshi, R., Tibbetts, K., Loos, Ruth, Karczewski, K. J. & Genome Aggregation Database Consortium, G. A. D. C., 2024, In: Nature. 625, 7993, p. 92-100 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Child-to-adult body size change and risk of type 2 diabetes and cardiovascular disease

    Carrasquilla, Germán D., Ängquist, Lars, Sørensen, Thorkild I.A., Kilpeläinen, Tuomas O. & Loos, Ruth, 2024, In: Diabetologia. 67, p. 864–873 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Elucidating pathways to pediatric obesity: a study evaluating obesity polygenic risk scores related to appetitive traits in children

    Renier, T. J., Yeum, D., Emond, J. A., Lansigan, R. K., Ballarino, G. A., Carlson, D. D., Loos, Ruth & Gilbert-Diamond, D., 2024, In: International Journal of Obesity. 48, p. 71-77

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Epigenetics of the non-coding RNA nc886 across blood, adipose tissue and skeletal muscle in offspring exposed to diabetes in pregnancy

    Hjort, Line, Bredgaard, S. S., Manitta, Eleonora, Marques, I., Sørensen, A. E., Martino, D., Grunnet, Louise Groth, Kelstrup, Louise, Houshmand-Oeregaard, A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Olsen, S. F., Saffery, R., Barrès, Romain, Damm, Peter, Vaag, A. A. & Dalgaard, L. T., 2024, In: Clinical Epigenetics. 16, 1, 15 p., 61.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Finding Ophthalmic Risk and Evaluating the Value of Eye exams and their predictive Reliability (FOREVER)—A cohort study in a Danish high street optician setting: Design and methodology

    Freiberg, J., Rovelt, J., Gazzard, G., Cour, M. L., Kolko, M., Torp‐Pedersen, C., Benn, M., Brunak, S., Cour, M. L., Tolstrup, J., Toft‐Petersen, A. P., Burgdorf, K. S., Banasik, K., Chmura, P. J., Freiberg, J., Rovelt, J., Thornit, D. N., Foster, P., Gazzard, G., Crabb, D. P. & 4 others, Viswanathan, A., Barman, Sarah, Owen, C. G. & Rudnicka, A. R., 2024, In: Acta Ophthalmologica. 102, 1, p. 80-90 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Genetic Variation and Obesity

    Loos, Ruth, 2024, Handbook of Obesity: Epidemiology, Etiology, and Physiopathology. Bray, G. A. & Bouchard, C. (eds.). 4 ed. CRC Press, Vol. 1. p. 113-122 10 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  10. Published

    Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

    Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., Rayner, N. W., Bocher, O., Arruda, A. L., Sonehara, K., Namba, S., Lee, S. S. K., Preuss, M. H., Petty, L. E., Schroeder, P., Vanderwerff, B. & 31 others, Kals, M., Bragg, F., Lin, K., Guo, X., Zhang, W., Yao, J., Kim, Y. J., Graff, M., Takeuchi, F., Nano, J., Lamri, A., Nakatochi, M., Moon, S., Scott, R. A., Cook, J. P., Lee, J., Pan, I., Taliun, D., Parra, E. J., Grarup, Niels, Chen, W., Bork-Jensen, J., Islam, M. T., Jørgensen, T., Linneberg, Allan René, Witte, D. R., Lind, L., Hansen, Torben, Pedersen, Oluf Borbye, Loos, Ruth & VA Million Veteran Program, V. M. V. P., 2024, In: Nature. 627, 8003, p. 347-357 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Accepted/In press

    Genetic underpinnings of fasting and oral glucose-stimulated based insulin sensitivity indices

    Suleman, Sufyan, Madsen, Anne Lundager, Ängquist, Lars, Schubert, Mikkel, Linneberg, Allan René, Loos, Ruth, Hansen, Torben & Grarup, Niels, 2024, (Accepted/In press) In: Journal of Clinical Endocrinology and Metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

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