A Gene Candidate Discovery Pipeline

A pipeline for propelling flagship investigations of organ cross-talk in metabolic research.

The delivery method follows three basic steps. Molecules are selected based on inclusion and exclusion criteria, the delivery method is investigated to see how the molecule can be delivered, and finally metabolic assays are conducted to evaluate their potentialIn addition to being of broad interest for understanding the fundamental mechanisms by which organs coordinate and regulate whole-body metabolism, secreted factors are prime candidates for therapies and drug development.

This pipeline is a system whereby potential secreted factors undergo an initial screening process, where they must pass several checkpoints before moving into a deeper evaluation of their potential for drug development.

The pipeline aims to encourage researchers to join forces and collaborate to accelerate the discovery of secreted proteins that play a role in regulation of energy metabolism.
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Portrait of Professor Romain Barrès

Flagship Contact

Romain Barrès

Phone +45 353-37025