Clemmensen Group

  1. 2024
  2. Published

    An RNA-seq atlas of mouse brain areas during fasting and diet-induced obesity

    Todorov, Petar Vladimirov, Klein, A. B., Egerod, Kristoffer Lihme, Clemmensen, Christoffer & Pers, Tune H, 2024, In: Scientific Data. 11, 8 p., 44.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Atlas of exercise-induced brain activation in mice

    Skovbjerg, G., Fritzen, Andreas Mæchel, Svendsen, C. S. A., Perens, J., Skytte, J. L., Lund, Camilla, Lund, Jens, Madsen, M. R., Roostalu, U., Hecksher-Sørensen, J. & Clemmensen, Christoffer, 2024, In: Molecular Metabolism. 82, 14 p., 101907.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R

    Lund, Camilla, Ranea-Robles, Pablo, Falk, S., Belmont-Rausch, Dylan Matthew, Skovbjerg, G., Vibe-Petersen, V. K., Krauth, Nathalie, Skytte, J. L., Vana, V., Roostalu, U., Pers, Tune H, Lund, Jens & Clemmensen, Christoffer, 2024, In: Nature Communications. 15, 1192.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published
  6. 2023
  7. Published

    Cross-species comparison of pregnancy-induced GDF15

    Klein, A. B., Ranea-Robles, Pablo, Nicolaisen, T. S., Gil, Cláudia, Johann, K., Prats Quesada, Júlia, Pistoljevic, N., Hviid, K. V. R., Olsen, L. F., Offersen, Simone Margaard, Helge, Jørn Wulff, Nielsen, Henriette Svarre, Bakker, J., Kleinert, Maximilian & Clemmensen, Christoffer, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E303-E309

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice

    Kanta, Josephine Maria, Deisen, L., Johann, K., Holm, Stephanie Kjærulff, Lundsgaard, Anne-Marie, Lund, Jens, Jähnert, M., Schürmann, A., Clemmensen, Christoffer, Kiens, Bente, Fritzen, Andreas Mæchel & Kleinert, Maximilian, 2023, In: Molecular Metabolism. 74, 10 p., 101760.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Do psychedelics have therapeutic potential for obesity?

    Fadahunsi, N., Knudsen, Gitte Moos & Clemmensen, Christoffer, 2023, In: Nature Reviews Endocrinology. 19, p. 1-2

    Research output: Contribution to journalComment/debate

  10. Published
  11. Published

    GDF15 increases insulin action in the liver and adipose tissue via a β-adrenergic receptor-mediated mechanism

    Sjøberg, K. A., Sigvardsen, Casper Møller, Alvarado-Diaz, A., Andersen, Nicoline Resen, Larance, M., Seeley, R. J., Schjerling, Peter, Knudsen, Jakob Grunnet, Katzilieris Petras, Georgios, Clemmensen, Christoffer, Jørgensen, S. B., De Bock, K. & Richter, Erik A., 2023, In: Cell Metabolism. 35, 8, p. 1327-1340.e5 19 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    GLP-1 and nicotine combination therapy engages hypothalamic and mesolimbic pathways to reverse obesity

    Falk, S., Petersen, Jonas Odgaard, Svendsen, C. S. A., Leguizamon, Cesar Ramon Romero, Jørgensen, Søren Heide, Krauth, Nathalie, Ludwig, M. Q., Jørgensen, Kathrine Lundø, Roostalu, U., Hjort-Gregersen, G. S., Nielsen, D. A. G., Ejdrup, Aske Lykke, Pers, Tune H, Dmytriyeva, O., Hecksher-Soerensen, J., Gether, Ulrik, Kohlmeier, Kristi Anne & Clemmensen, Christoffer, 2023, In: Cell Reports. 42, 5, 18 p., 112466.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Identification of GDF15 peptide fragments inhibiting GFRAL receptor signaling

    Alexopoulou, Flora, Buch-Månson, N., Pedersen, S. L., Vrang, N., Fink, L. N. & Strømgaard, Kristian, 2023, In: Peptides. 168, 7 p., 171063.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: a systematic review

    Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD PMDI, A. P., 2023, In: Communications Medicine. 3, 17 p., 133.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Is lactate a driver of skin burn-induced adipose browning?

    Lund, Jens, Johansen, Valdemar Brimnes Ingemann, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E421-E422 2 p.

    Research output: Contribution to journalComment/debate

  16. Published

    Ketone monoester increases circulating levels of LEAP2 and decreases appetite in healthy men

    Holm, Stephanie Kjærulff, Vestergaard, E. T., Zubanovic, N. B., Byberg, Sarah, Clemmensen, Christoffer, Holst, Birgitte & Thomsen, H. H., 2023, In: Diabetes, Obesity and Metabolism. 25, 7, p. :2023–2027

    Research output: Contribution to journalLetterpeer-review

  17. Published

    LEAP2 is associated with cardiometabolic markers but is unchanged by antidiabetic treatment in people with prediabetes

    Byberg, Sarah, Blond, Martin Bæk, Holm, Stephanie Kjærulff, Amadid, H., Nielsen, L. B., Clemmensen, K. K. B., Færch, K. & Holst, Birgitte, 2023, In: American journal of physiology. Endocrinology and metabolism. 325, 3, p. E244-E251

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Linking Hypothermia and Altered Metabolism with TrkB Activation

    Alitalo, O., González-Hernández, G., Rosenholm, Marko, Kohtala, P., Matsui, N., Müller, H. K., Theilmann, W., Klein, A., Kärkkäinen, O., Rozov, S., Rantamäki, T. & Kohtala, S., 2023, In: ACS Chemical Neuroscience. 14, 17, p. 3212–3225

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    Neuronal Blockade of Thyroid Hormone Signaling Increases Sensitivity to Diet-Induced Obesity in Adult Male Mice

    Rial-Pensado, E., Canaple, L., Guyot, R., Clemmensen, Christoffer, Wiersema, J., Wu, S., Richard, S., Boelen, A., Müller, T. D., López, M., Flamant, F. & Gauthier, K., 2023, In: Endocrinology. 164, 4

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    Overlooked confounding in studies of metabolite salts

    Lund, Jens, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: Nature Metabolism. 5, 4, p. 542-543 2 p.

    Research output: Contribution to journalComment/debate

  21. Published

    Physiological protection against weight gain: evidence from overfeeding studies and future directions

    Lund, Jens & Clemmensen, Christoffer, 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 11 p., 2022.0229.

    Research output: Contribution to journalReviewpeer-review

  22. Published

    ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging

    Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, Lund, Anders H., Treebak, Jonas Thue, Olsen, Jesper Velgaard, Poulsen, Steen Seier, Pownall, M. E., Jensen, Benjamin Anderschou Holbech, Clemmensen, Christoffer, Gerhart-Hines, Zach, Gatfield, D. & Bekker-Jensen, Simon Holst, 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Role of sociodemographic, clinical, behavioral, and molecular factors in precision prevention of type 2 diabetes: a systematic review

    Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD Precision Medicine in Diabetes Initiative, A. P. M. I. D. I., 2023, medRxiv.

    Research output: Working paperPreprintResearch

  24. Published

    Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

    Tobias, D. K., Merino, J., Ahmad, A., Aiken, C., Benham, J. L., Bodhini, D., Clark, A. L., Colclough, K., Corcoy, R., Cromer, S. J., Duan, D., Felton, J. L., Francis, E. C., Gillard, P., Gingras, V., Gaillard, R., Haider, E., Hughes, A., Ikle, J. M., Jacobsen, L. M. & 180 others, Kahkoska, A. R., Kettunen, J. L. T., Kreienkamp, R. J., Lim, L. L., Männistö, J. M. E., Massey, R., Mclennan, N. M., Miller, R. G., Morieri, M. L., Most, J., Naylor, R. N., Ozkan, B., Patel, K. A., Pilla, S. J., Prystupa, K., Raghavan, S., Rooney, M. R., Schön, M., Semnani-Azad, Z., Sevilla-Gonzalez, M., Svalastoga, P., Takele, W. W., Tam, C. H. T., Thuesen, Anne Cathrine Baun, Tosur, M., Wallace, A. S., Wang, C. C., Wong, J. J., Yamamoto, J. M., Young, K., Amouyal, C., Lepola, Mette Andersen, Bonham, M. P., Chen, M., Cheng, F., Chikowore, T., Chivers, S. C., Clemmensen, Christoffer, Dabelea, D., Dawed, A. Y., Deutsch, A. J., Dickens, L. T., DiMeglio, L. A., Dudenhöffer-Pfeifer, M., Evans-Molina, C., Fernández-Balsells, M. M., Fitipaldi, H., Fitzpatrick, S. L., Gitelman, S. E., Goodarzi, M. O., Grieger, J. A., Guasch Ferre, Marta, Habibi, N., Hansen, Torben, Huang, C., Harris-Kawano, A., Ismail, H. M., Hoag, B., Johnson, R. K., Jones, A. G., Koivula, R. W., Leong, A., Leung, G. K. W., Libman, I. M., Liu, K., Long, S. A., Lowe, W. L., Morton, R. W., Motala, A. A., Onengut-Gumuscu, S., Pankow, J. S., Pathirana, M., Pazmino, S., Perez, D., Petrie, J. R., Powe, C. E., Quinteros, A., Jain, R., Ray, D., Ried-Larsen, M., Saeed, Z., Santhakumar, V., Kanbour, S., Sarkar, S., Monaco, G. S. F., Scholtens, D. M., Selvin, E., Sheu, W. H. H., Speake, C., Stanislawski, M. A., Steenackers, N., Steck, A. K., Stefan, N., Støy, J., Taylor, R., Tye, S. C., Ukke, G. G., Urazbayeva, M., Van der Schueren, B., Vatier, C., Wentworth, J. M., Hannah, W., White, S. L., Yu, G., Zhang, Y., Zhou, S. J., Beltrand, J., Polak, M., Aukrust, I., de Franco, E., Flanagan, S. E., Maloney, K. A., McGovern, A., Molnes, J., Nakabuye, Mariam, Njølstad, P. R., Pomares-Millan, H., Provenzano, M., Saint-Martin, C., Zhang, C., Zhu, Y., Auh, S., de Souza, R., Fawcett, A. J., Gruber, C., Mekonnen, E. G., Mixter, E., Sherifali, D., Eckel, R. H., Nolan, J. J., Philipson, L. H., Brown, R. J., Billings, L. K., Boyle, K., Costacou, T., Dennis, J. M., Florez, J. C., Gloyn, A. L., Gomez, M. F., Gottlieb, P. A., Greeley, S. A. W., Griffin, K., Hattersley, A. T., Hirsch, I. B., Hivert, M. F., Hood, K. K., Josefson, J. L., Kwak, S. H., Laffel, L. M., Lim, S. S., Loos, Ruth, Ma, R. C. W., Mathieu, C., Mathioudakis, N., Meigs, J. B., Misra, S., Mohan, V., Murphy, R., Oram, R., Owen, K. R., Ozanne, S. E., Pearson, E. R., Perng, W., Pollin, T. I., Pop-Busui, R., Pratley, R. E., Redman, L. M., Redondo, M. J., Reynolds, R. M., Semple, R. K., Sherr, J. L., Sims, E. K., Sweeting, A., Tuomi, T., Udler, M. S., Vesco, K. K., Vilsbøll, Tina, Wagner, R., Rich, S. S. & Franks, P. W., 2023, In: Nature Medicine. 29, 10, p. 2438-2457 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα

    Griem-Krey, Nane, Klein, A. B., Clausen, B. H., Namini, M. R. J., Nielsen, P. V., Bhuiyan, M., Nagaraja, R. Y., De Silva, T. M., Sobey, C. G., Cheng, H. C., Orset, C., Vivien, D., Lambertsen, K. L., Clarkson, A. N. & Wellendorph, Petrine, 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 8, p. 1419-1434

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions

    Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, Clemmensen, Christoffer, 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    The biochemistry and physiology of long-chain dicarboxylic acid metabolism

    Ranea-Robles, Pablo & Houten, S. M., 2023, In: Biochemical Journal. 480, 9, p. 607-627 21 p.

    Research output: Contribution to journalReviewpeer-review

  28. Published

    The dietary regulation of LEAP2 depends on meal composition in mice

    Gradel, Anna Katrina Jógvansdóttir, Holm, Stephanie Kjærulff, Byberg, Sarah, Merkestein, M., Hogendorf, W. F. J., Lund, M. L., Buijink, Jesse A., Damgaard, J., Lykkesfeldt, Jens & Holst, Birgitte, 2023, In: FASEB Journal. 37, 6, 21 p., 22923.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Uncovering CNS access of lipidated exendin-4 analogues by quantitative whole-brain 3D light sheet imaging

    Skovbjerg, G., Roostalu, U., Salinas, C. G., Skytte, J. L., Perens, J., Clemmensen, Christoffer, Elster, L., Frich, C. K., Hansen, H. H. & Hecksher-Sørensen, J., 2023, In: Neuropharmacology. 238, 109637.

    Research output: Contribution to journalJournal articlepeer-review

  30. 2022
  31. Published

    Acute and long-term effects of psilocybin on energy balance and feeding behavior in mice

    Fadahunsi, N., Lund, Jens, Breum, Alberte Wollesen, Mathiesen, C. V., Larsen, I. B., Knudsen, Gitte Moos, Klein, A. B. & Clemmensen, Christoffer, 2022, In: Translational Psychiatry. 12, 12 p., 330.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2

    Holm, Stephanie Kjærulff, Husted, Anna Sofie, Skov, Louise Julie, Morville, T. H., Hagemann, C. A., Jorsal, T., Dall, M., Jakobsen, Alexander, Klein, A. B., Treebak, Jonas Thue, Knop, Filip Krag, Schwartz, Thue W., Clemmensen, Christoffer & Holst, Birgitte, 2022, In: Endocrinology. 163, 6, 13 p., bqac038.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Divergent Roles of α5 and β4 Nicotinic Receptor Subunits in Food Reward and Nicotine-induced Weight Loss in Male Mice

    Breum, Alberte Wollesen, Falk, S., Svendsen, C. S. A., Nicolaisen, T. S., Mathiesen, C. V., Maskos, U. & Clemmensen, Christoffer, 2022, In: Endocrinology. 163, 7, 9 p., bqac079.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Extreme duration exercise affects old and younger men differently

    Frandsen, J., Sahl, R. E., Rømer, T., Thunestvedt Hansen, M., Nielsen, A. B., Lie-Olesen, M. M., Rasmusen, H. K., Søgaard, D., Ingersen, A., Rosenkilde, M., Westerterp, K., Holst, J. J., Andersen, J. L., Markowski, A. R., Blachnio-Zabielska, A., Clemmensen, C., Sacchetti, M., Cataldo, A., Traina, M., Larsen, S. & 2 others, Dela, Flemming & Helge, Jørn Wulff, 2022, In: Acta Physiologica. 235, 3, e13816.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    GDF15 in appetite and exercise: Essential player or coincidental bystander?

    Klein, A. B., Kleinert, Maximilian, Richter, Erik A. & Clemmensen, Christoffer, 2022, In: Endocrinology. 163, 1, p. 1-10 10 p.

    Research output: Contribution to journalReviewpeer-review

  36. Published

    GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice

    Quarta, C., Stemmer, K., Novikoff, A., Yang, B., Klingelhuber, F., Harger, A., Bakhti, M., Bastidas-Ponce, A., Baugé, E., Campbell, J. E., Capozzi, M., Clemmensen, C., Collden, G., Cota, P., Douros, J., Drucker, D. J., DuBois, B., Feuchtinger, A., Garcia-Caceres, C., Grandl, G. & 20 others, Hennuyer, N., Herzig, S., Hofmann, S. M., Knerr, P. J., Kulaj, K., Lalloyer, F., Lickert, H., Liskiewicz, A., Liskiewicz, D., Maity, G., Perez-Tilve, D., Prakash, S., Sanchez-Garrido, M. A., Zhang, Q., Staels, B., Krahmer, N., DiMarchi, R. D., Tschöp, M. H., Finan, B. & Müller, T. D., 2022, In: Nature Metabolism. 4, 8, p. 1071-1083 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published
  38. Published
  39. Published

    Outrunning obesity with Lac-Phe?

    Lund, Jens, Clemmensen, Christoffer & Schwartz, Thue W., 2022, In: Cell Metabolism. 34, 8, p. 1085-1087 3 p.

    Research output: Contribution to journalComment/debatepeer-review

  40. Published

    RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma

    Andreassen, C. H., Lorenzen, M., Nielsen, J. E., Kafai Yahyavi, S., Toft, Birgitte Grønkær, Ingerslev, L. R., Clemmensen, Christoffer, Rasmussen, Lene Juel, Bokemeyer, C., Juul, Anders, Jørgensen, A. & Jensen, M. B., 2022, In: British Journal of Cancer. 127, p. 408-421

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response

    Snieckute, Goda, Genzor Garbayo, Aitana Victoria, Vind, Anna Constance, Jordan, Laura Ryder, Stoneley, M., Chamois, S., Dreos, R., Nordgaard, C., Sass, Frederike, Blasius, Melanie, López, A. R., Brynjólfsdóttir, S. H., Andersen, Kasper Langebjerg, Willis, A. E., Frankel, Lisa, Poulsen, Steen Seier, Gatfield, D., Gerhart-Hines, Zach, Clemmensen, Christoffer & Bekker-Jensen, Simon Holst, 2022, In: Cell Metabolism. 34, 12, p. 2036-2046.e8 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance

    Klein, A. B., Nicolaisen, T. S., Johann, K., Fritzen, Andreas Mæchel, Mathiesen, C. V., Gil, Cláudia, Pilmark, N. S., Karstoft, Kristian, Blond, Martin Bæk, Quist, Jonas Salling, Seeley, R. J., Færch, K., Lund, Jens, Kleinert, Maximilian & Clemmensen, Christoffer, 2022, In: Cell Reports. 40, 8, 111258.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    The physiology of experimental overfeeding in animals

    Ranea-Robles, Pablo, Lund, Jens & Clemmensen, Christoffer, 2022, In: Molecular Metabolism. 64, 15 p., 101573.

    Research output: Contribution to journalReviewpeer-review

  44. Published

    ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle

    Nordgaard, C., Vind, A. C., Stonadge, A., Kjøbsted, R., Snieckute, G., Antas, P., Blasius, M., Reinert, M. S., Del Val, A. M., Bekker-Jensen, D. B., Haahr, P., Miroshnikova, Y. A., Mazouzi, A., Falk, S., Perrier-Groult, E., Tiedje, C., Li, X., Jakobsen, J. R., Jørgensen, N. O., Wojtaszewski, J. & 12 others, Mallein-Gerin, F., Andersen, J. L., Pennisi, C. P., Clemmensen, Christoffer, Kassem, Moustapha Saad El-Deen, Jafari Kermani, Abbas, Brummelkamp, T., Li, V. S., Wickström, S. A., Olsen, Jesper Velgaard, Blanco, G. & Bekker-Jensen, Simon Holst, 2022, In: E M B O Journal. 41, 17, 19 p., e111650.

    Research output: Contribution to journalJournal articlepeer-review

  45. 2021
  46. Published

    Acute erythropoietin injection increases muscle mitochondrial respiratory capacity in young men: A double-blinded randomized crossover trial

    Larsen, Steen, Søndergård, S. D., Sahl, Ronni Eg, Frandsen, J., Morville, T., Dela, Flemming & Helge, Jørn Wulff, 2021, In: Journal of Applied Physiology. 131, 4, p. 1340-1347

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    CB1 and GLP-1 Receptors Cross Talk Provides New Therapies for Obesity

    Zizzari, P., He, R., Falk, S., Bellocchio, L., Allard, C., Clark, S., Lesté-Lasserre, T., Marsicano, G., Clemmensen, Christoffer, Perez-Tilve, D., Finan, B., Cota, D. & Quarta, C., 2021, In: Diabetes. 70, 2, p. 415-422 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    Discovery of thymosin β4 as a human exerkine and growth factor

    Gonzalez-Franquesa, A., Stocks, Ben Nicholas, Borg, M. L., Kuefner, M., Kellezi, Emilie Dalbram, Nielsen, Thomas Svava, Agrawal, A., Pankratova, Stanislava, Chibalin, A. V., Karlsson, H. K. R., Gheibi, S., Björnholm, M., Jørgensen, Niklas Rye, Clemmensen, Christoffer, Treebak, Jonas Thue, Hostrup, Morten, Krook, A., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: American Journal of Physiology: Cell Physiology. 321, 5, p. C770-C778 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Maximal fat oxidation rate is higher in fit women and unfit women with obesity, compared to normal weight unfit women

    Frandsen, J., Hansen, I. M. D., Wismann, J. F., Olsen, M. H., Brage-Andersen, M. R., Sahl, Ronni Eg, Hansen, M., Ingersen, Arthur, Modvig, J. L., Schmücker, M., brl298, brl298, Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 11, p. E4389-E4399 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

    Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, Seeley, R. J., Kleinert, Maximilian, Kiens, Bente, Richter, Erik A. & Clemmensen, Christoffer, 2021, In: Nature Communications. 12, 9 p., 1041.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Reliability and variation in mitochondrial respiration in human adipose tissue

    Sahl, Ronni Eg, Høy Helms, E. F., Schmücker, Malte, Flensted-Jensen, Mathias, Ingersen, Arthur, Morville, T., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 2021, In: Adipocytes. 10, 1, p. 605-611 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  52. Published

    Spinal astroglial cannabinoid receptors control pathological tremor

    Carlsen, Eva Maria Meier, Falk, S., Skupio, U., Robin, L., Zottola, A. C. P., Marsicano, G. & Perrier, Jean-Francois Marie, 2021, In: Nature Neuroscience. 24, p. 658–666 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Structure-Activity Studies of 3,9-Diazaspiro[5.5]undecane-Based ?-Aminobutyric Acid Type A Receptor Antagonists with Immunomodulatory Effect

    Bavo, Francesco, De-Jong, H., Petersen, Jonas Odgaard, Falk-Petersen, C. B., Löffler, R., Sparrow, E., Rostrup, F., Eliasen, Jannik Nicklas, Wilhelmsen, K. S., Barslund, K., Bundgaard, C., Nielsen, Birgitte, Kristiansen, Uffe, Wellendorph, Petrine, Bogdanov, Y. & Frølund, Bente, 2021, In: Journal of Medicinal Chemistry. 64, 24, p. 17795-17812

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    Systematic review and consensus definitions for the Standardized Endpoints in Perioperative Medicine (StEP) initiative: cardiovascular outcomes

    StEP COMPAC Group, S. C. G., 2021, In: British Journal of Anaesthesia. 126, 1, p. 56-66 11 p.

    Research output: Contribution to journalReviewpeer-review

  55. Published

    The effects of 3 weeks of oral glutathione supplementation on whole body insulin sensitivity in obese males with and without type 2 diabetes: a randomized trial

    Søndergård, S. D., Cintin, I., Kuhlman, A. B., Morville, T. H., Bergmann, M. L., Kjær, L. K., Poulsen, Henrik Enghusen, Giustarini, D., Rossi, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 9, 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    α-Synuclein Responses in the Laterodorsal Tegmentum, the Pedunculopontine Tegmentum and the Substantia Nigra: Implications for Early Appearance of Sleep Disorders in Parkinson’s Disease

    Brito dos Santos, Altair, Skaanning, L. K., Mikkelsen, E., Leguizamon, Cesar Ramon Romero, Kristensen, M. P., Klein, A. B., Thaneshwaran, S. S., Langkilde, Annette Eva & Kohlmeier, Kristi Anne, 2021, In: Journal of Parkinson's Disease. 11, 4, p. 1773-1790

    Research output: Contribution to journalJournal articlepeer-review

  57. 2020
  58. Published

    Har du let eller svært ved at tage på? Måske skyldes det kalorierne i toilettet

    Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 1 Oct 2020, Videnskab.dk, ForskerZonen.

    Research output: Other contributionNet publication - Internet publicationCommunication

  59. Published

    Mechanism and Binding Site of the ASIC1A-Big Dynorphin Interaction

    Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedstrom, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 7 Feb 2020, In: Biophysical Journal. 118, 3, supplement 1, p. 582A-582A

    Research output: Contribution to journalConference abstract in journalpeer-review

  60. Published

    Compounds for the treatment of acute brain injury

    Klein, A. B., Leurs, U., Houlton, J., Clausen, Rasmus Prætorius, Frølund, Bente, Clarkson, A. & Wellendorph, Petrine, 2020, Patent No. CN111989094, 24 Nov 2020, Priority date 1 Feb 2019, Priority No. PCT/DK2019/050041

    Research output: Patent

  61. Published

    Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation

    Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Nicolaisen, T. S., Carl, Christian Strini, Sjøberg, K. A., Raun, Steffen Henning, Klein, A. B., Sanchez-Quant, E., Langer, J., Ørskov, Cathrine, Clemmensen, Christoffer, Tschöp, M. H., Richter, Erik A., Kiens, Bente & Kleinert, Maximilian, 2020, In: Journal of Lipid Research. 61, 1, p. 10-19 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  62. Published

    Mechanism and site of action of big dynorphin on ASIC1a

    Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedström, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 13, p. 7447-7454

    Research output: Contribution to journalJournal articlepeer-review

  63. Published

    Muscarinic receptors in energy homeostasis: Physiology and pharmacology

    Falk, S., Lund, Camilla & Clemmensen, Christoffer, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, Suppl. 6, p. 66-76 11 p.

    Research output: Contribution to journalReviewpeer-review

  64. Published

    Next Generation Diabetes Scientists Shape Global Research Culture: A reflective proposal from postdoctoral researchers in diabetes research

    Gonzalez-Franquesa, A., Carrasquilla Lopez, G. D., Mamidi, A., Ghiasi, S. M., Juel, H. B., Falk, S., Isidor, M. S., Gillberg, L. M. E., Huang, L. O., Quist, J. S., Knudsen, J. R., Quaranta, R., Tozzi, M., Mikkelsen, R. B., Dall, M., Drag, M. H., Small, L. B., Altıntaş, A., Osborne, B., Modvig, I. M. & 11 others, Husted, Anna Sofie, Brown, E. L., Bak, Emilie Glad, Bastos Peluso, A. A., Finger, Fabian Michael, Grunddal, Kaare Villum, Rupar, K., Henningsen, J. B., Pedersen, M. H., Plucinska, Kaja & Attendees of the Danish Diabetes Academy Winter School 2019, A. O. T. D. D. A. W. S. 2., 2020, In: Acta Physiologica. 229, 2, 5 p., e13455.

    Research output: Contribution to journalComment/debate

  65. Published

    Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity

    Jall, S., De Angelis, M., Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Nicolaisen, T. S., Klein, A. B., Novikoff, A., Sachs, S., Richter, Erik A., Kiens, Bente, Schramm, K., Tschöp, M. H., Stemmer, K., Clemmensen, Christoffer, Müller, T. D. & Kleinert, Maximilian, 2020, In: Diabetologia. 63, 6, p. 1236-1247 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  66. Published

    Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans

    Morville, T., Sahl, Ronni Eg, Moritz, Thomas, Helge, Jørn Wulff & Clemmensen, Christoffer, 2020, In: Cell Reports. 33, 13, 14 p., 108554.

    Research output: Contribution to journalJournal articlepeer-review

  67. Published

    Role of Energy Excretion in Human Body Weight Regulation

    Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 2020, In: Trends in Endocrinology and Metabolism. 31, 10, p. 705-708 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  68. Published

    The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation

    Fischer, K., Fenzl, A., Liu, D., Dyar, K. A., Kleinert, M., Brielmeier, M., Clemmensen, C., Fedl, A., Finan, B., Gessner, A., Jastroch, M., Huang, J., Keipert, S., Klingenspor, M., Brüning, J. C., Kneilling, M., Maier, F. C., Othman, A. E., Pichler, B. J., Pramme-Steinwachs, I. & 13 others, Sachs, S., Scheideler, A., Thaiss, W. M., Uhlenhaut, H., Ussar, S., Woods, S. C., Zorn, J., Stemmer, K., Collins, S., Diaz-Meco, M., Moscat, J., Tschöp, M. H. & Müller, T. D., 2020, In: Nature Communications. 11, 1, 13 p., 2306.

    Research output: Contribution to journalJournal articlepeer-review

  69. Published

    The unidentified hormonal defense against weight gain

    Lund, Jens, Lund, Camilla, Morville, T. H. & Clemmensen, Christoffer, 2020, In: PLOS Biology. 18, 2, 14 p., e3000629.

    Research output: Contribution to journalJournal articlepeer-review

  70. Published

    Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure

    Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, Jens, Ingerslev, L. R., Fritzen, Andreas Mæchel, Carl, Christian Strini, Lundsgaard, Anne-Marie, Frost, M., Ma, Tao, Schjerling, P., Gerhart-Hines, Zach, Flamant, F., Gauthier, K., Larsen, Steen, Richter, Erik A., Kiens, Bente & Clemmensen, Christoffer, 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  71. Published

    Will the COVID-19 pandemic worsen the obesity epidemic?

    Clemmensen, Christoffer, Petersen, M. B. & Sørensen, Thorkild I.A., 2020, In: Nature Reviews Endocrinology. 2 p.

    Research output: Contribution to journalEditorialpeer-review

  72. 2019
  73. Published

    Chronic high dose P2X7 receptor inhibition exacerbates cancer-induced bone pain

    Falk, S., Appel, C. K., Bennedbæk, H. B., Al-Dihaissy, T., Unger, A., Dinkel, K. & Heegaard, Anne-Marie, 15 Feb 2019, In: European Journal of Pharmacology. 845, p. 48-55 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  74. Published

    Aerobic Exercise Performance and Muscle Strength in Statin Users-The LIFESTAT Study

    Morville, T., Dohlmann, T. L., Kuhlman, A. B., Sahl, Ronni Eg, Kriegbaum, Margit, Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Medicine and Science in Sports and Exercise. 51, 7, p. 1429-1437 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  75. Published

    Designing Poly-agonists for Treatment of Metabolic Diseases: Challenges and Opportunities

    Petersen, Jonas Odgaard, Strømgaard, Kristian, Frølund, Bente & Clemmensen, Christoffer, 2019, In: Drugs. 79, 11, p. 1187-1197 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  76. Published

    Emerging hormonal-based combination pharmacotherapies for the treatment of metabolic diseases

    Clemmensen, Christoffer, Finan, B., Müller, T. D., DiMarchi, R. D., Tschöp, M. H. & Hofmann, S. M., 2019, In: Nature Reviews Endocrinology. 15, p. 90-104

    Research output: Contribution to journalReviewpeer-review

  77. Published

    GLP-1/dexamethasone inhibits food reward without inducing mood and memory deficits in mice

    Decarie-Spain, L., Fisette, A., Zhu, Z., Yang, B., DiMarchi, R. D., Tschoep, M. H., Finan, B., Fulton, S. & Clemmensen, Christoffer, 2019, In: Neuropharmacology. 151, p. 55-63

    Research output: Contribution to journalJournal articlepeer-review

  78. Published

    Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway

    Ratner, C., He, Z., Grunddal, Kaare Villum, Skov, Louise Julie, Hartmann, Bolette, Zhang, F., Feuchtinger, A., Bjerregaard, Anette, Christoffersen, Christina, Tschöp, M. H., Finan, B., DiMarchi, R. D., Leinninger, G. M., Williams, K. W., Clemmensen, Christoffer & Holst, Birgitte, 2019, In: Diabetes. 68, 6, p. 1329-1340

    Research output: Contribution to journalJournal articlepeer-review

  79. Published

    Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice

    Jall, S., Finan, B., Collden, G., Fischer, K., Dong, X., Tschoep, M. H., Mueller, T. D. & Clemmensen, Christoffer, 2019, In: Molecular Metabolism. 23, p. 75-81

    Research output: Contribution to journalJournal articlepeer-review

  80. Published

    Unge forskere: S-løftebrud er en katastrofe for universiteterne

    Aguirre, V., Andersen, C., Andersen, P. R., Bjørk, R., Clemmensen, C., Dalsgaard, P., Danbolt, M., Dimke, H., Engberg-Pedersen, A., Feliu, E., Jauffred, L., Jønsson, K., Kornum, B. R., Kropp, K., Laustsen, A., Levisen, C., Lock, N., Lomborg, S., Møller, N. M., Niss, K. & 5 others, Pedersen, B. P., Pristed, B. B., Sørensen, Thomas Just, Ulstrup, S. & Vallgårda, Karen Asta Arnfred, 2019

    Research output: Other contributionCommunication

  81. 2018
  82. Published

    Anti-Obesity Therapy: from Rainbow Pills to Polyagonists.

    Müller, T., Clemmensen, Christoffer, Finan, B., DiMarchi, R. & Tschöp, M., Oct 2018, In: Pharmacological Reviews.

    Research output: Contribution to journalJournal articlepeer-review

  83. 2015
  84. Published

    Accelerated food source location in aging Drosophila.

    Egenriether, S., Chow, E., Krauth, Nathalie & Giebultowicz, J., 23 Jun 2015, In: Aging Cell.

    Research output: Contribution to journalJournal articlepeer-review

  85. Published

    Novel combinatorial therapies involving leptin: Opportunities for mechanistic advances and therapeutic translation in human diseases

    Müller, T. D., Clemmensen, Christoffer, Finan, B., Dimarchi, R. D. & Tschöp, M. H., 1 Jan 2015, Leptin: Regulation and Clinical Applications. Springer, p. 267-279 13 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review