Outrunning obesity with Lac-Phe?

Research output: Contribution to journalComment/debateResearchpeer-review

Lactate released from skeletal muscle during high-intensity exercise gives rise to a surge in circulating lactate-derived pseudo-dipeptide metabolites including N-lactoyl-phenylalanine (Lac-Phe). In a recent Nature paper, Li et al. use genetic and pharmacological evidence to now propose Lac-Phe to be an “exercise hormone” that suppresses appetite and obesity.

Original languageEnglish
JournalCell Metabolism
Issue number8
Pages (from-to)1085-1087
Number of pages3
Publication statusPublished - 2022

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© 2022 Elsevier Inc.

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