Gerhart-Hines Group

  1. 2024
  2. Published

    Atlas of exercise-induced brain activation in mice

    Skovbjerg, G., Fritzen, Andreas Mæchel, Svendsen, C. S. A., Perens, J., Skytte, J. L., Lund, Camilla, Lund, Jens, Madsen, M. R., Roostalu, U., Hecksher-Sørensen, J. & Clemmensen, Christoffer, 2024, In: Molecular Metabolism. 82, 14 p., 101907.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M

    Dollet, L., Lundell, L. S., Chibalin, A. V., Pendergrast, L. A., Pillon, N. J., Lansbury, Elizabeth Laura, Elmastas, M., Frendo-Cumbo, S., Jalkanen, J., de Castro Barbosa, T., Cervone, D. T., Caidahl, K., Dmytriyeva, O., Deshmukh, Atul Shahaji, Barrès, Romain, Rydén, M., Wallberg-Henriksson, H., Zierath, Juleen R & Krook, A., 2024, In: Cell Reports Medicine. 5, 1, 20 p., 101348.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    MCT1 helps brown fat suck up succinate

    Lund, Jens, Isidor, Marie Sophie & Gerhart-Hines, Zach, 2024, In: Nature Metabolism. 6, p. 387–388

    Research output: Contribution to journalLetterpeer-review

  5. Published

    Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R

    Lund, Camilla, Ranea-Robles, Pablo, Falk, S., Belmont-Rausch, Dylan Matthew, Skovbjerg, G., Vibe-Petersen, V. K., Krauth, Nathalie, Skytte, J. L., Vana, V., Roostalu, U., Pers, Tune H, Lund, Jens & Clemmensen, Christoffer, 2024, In: Nature Communications. 15, 1192.

    Research output: Contribution to journalJournal articlepeer-review

  6. 2023
  7. Published

    Acute Deletion of the Glucocorticoid Receptor in Hepatocytes Disrupts Postprandial Lipid Metabolism in Male Mice

    Correia, C. M., Præstholm, S. M., Havelund, J. F., Boel, Felix, Siersbæk, M. S., Ebbesen, M. F., Gerhart-Hines, Zach, Heeren, J., Brewer, J., Larsen, Steen, Blagoev, B., Færgeman, N. J. & Grøntved, L., 2023, In: Endocrinology. 164, 10, p. 1-17 164.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Chasing the hunger-suppressive signals of human exercise

    Brunetta, H. S. & Lund, Jens, 2023, In: Journal of Physiology. 601, 16, p. 3441-3442 2 p.

    Research output: Contribution to journalComment/debatepeer-review

  9. Published

    Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice

    Kanta, Josephine Maria, Deisen, L., Johann, K., Holm, Stephanie Kjærulff, Lundsgaard, Anne-Marie, Lund, Jens, Jähnert, M., Schürmann, A., Clemmensen, Christoffer, Kiens, Bente, Fritzen, Andreas Mæchel & Kleinert, Maximilian, 2023, In: Molecular Metabolism. 74, 10 p., 101760.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Editorial overview: Fat tissue in focus: Assembled deeply insightful perspectives on state-of-the-art explorations

    Gerhart-Hines, Zach & Loos, Ruth, 2023, In: Current Opinion in Genetics and Development. 83, 102117.

    Research output: Contribution to journalEditorial

  11. Published

    Effect of Simvastatin Treatment on Mitochondrial Function and Inflammatory Status of Human White Adipose Tissue

    Bager Christensen, I., Blom, Ida, Dohlmann, T. L., Finger, Fabian Michael, Helge, Jørn Wulff, Gerhart-Hines, Zach, Dela, Flemming & Larsen, Steen, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 10, p. e916-e922 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Full activation of thermogenesis in brown adipocytes requires Basigin action

    Rupar, K., Isidor, Marie Sophie, Argemi Muntadas, Lidia, Agueda Oyarzabal, Marina, Plucinska, Kaja, Brown, E. L., Mattanovich, M., Bossi, Simone, Tozzi, M., Tandio, David, Petersen, P. S. S., Henriksen, T. I., Trošt, K., Hansen, Jacob B., Gerhart-Hines, Zach, Nielsen, S., Moritz, Thomas & Emanuelli, Brice, 2023, In: F E B S Journal. 290, 10, p. 2673-2691

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Is lactate a driver of skin burn-induced adipose browning?

    Lund, Jens, Johansen, Valdemar Brimnes Ingemann, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E421-E422 2 p.

    Research output: Contribution to journalComment/debate

  14. Published

    Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis

    Johnson, J. M., Peterlin, A. D., Balderas, E., Sustarsic, E. G., Maschek, J. A., Lang, M. J., Jara-Ramos, A., Panic, V., Morgan, J. T., Villanueva, C. J., Sanchez, A., Rutter, J., Lodhi, I. J., Cox, J. E., Fisher-Wellman, K. H., Chaudhuri, D., Gerhart-Hines, Zach & Funai, K., 2023, In: Science Advances. 9, 8, 15 p., eade7864.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner

    Basse, A. L., Nielsen, K. N., Karavaeva, Iuliia, Ingerslev, L. R., Ma, Tao, Havelund, J. F., Nielsen, Thomas Svava, Frost, M., Peics, J., Kellezi, Emilie Dalbram, Dall, M., Zierath, Juleen R, Barrès, Romain, Færgeman, N. J., Treebak, Jonas Thue & Gerhart-Hines, Zach, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2220102120.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

    Peluso, A. A., Lundgaard, A. T., Babaei, P., Mousovich-Neto, F., Rocha, A. L., Damgaard, M. V., Bak, E. G., Gnanasekaran, T., Dollerup, O. L., Trammell, S. A. J., Nielsen, T. S., Kern, T., Abild, C. B., Sulek, K., Ma, T., Gerhart-Hines, Z., Gillum, M. P., Arumugam, M., Ørskov, C., McCloskey, D. & 4 others, Jessen, N., Herrgård, M. J., Mori, M. A. S. & Treebak, Jonas Thue, 2023, In: npj Aging. 9, 21 p., 7.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Overlooked confounding in studies of metabolite salts

    Lund, Jens, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: Nature Metabolism. 5, 4, p. 542-543 2 p.

    Research output: Contribution to journalComment/debate

  18. Published

    PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity

    Backe, M. B., Andersen, Rita Chan, Jensen, M., Jin, C., Hundahl, C., Dmytriyeva, O., Treebak, Jonas Thue, Hansen, J. B., Gerhart-Hines, Zach, Madsen, Kenneth Lindegaard & Holst, Birgitte, 2023, In: Journal of the endocrine society. 7, 6, p. 1-13 bvad057.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    Physiological protection against weight gain: evidence from overfeeding studies and future directions

    Lund, Jens & Clemmensen, Christoffer, 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 11 p., 2022.0229.

    Research output: Contribution to journalReviewpeer-review

  20. Published

    ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging

    Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, Lund, Anders H., Treebak, Jonas Thue, Olsen, Jesper Velgaard, Poulsen, Steen Seier, Pownall, M. E., Jensen, Benjamin Anderschou Holbech, Clemmensen, Christoffer, Gerhart-Hines, Zach, Gatfield, D. & Bekker-Jensen, Simon Holst, 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    TNIK is a conserved regulator of glucose and lipid metabolism in obesity

    Pham, Tang Cam Phung, Dollet, L., Ali, Mona Sadek, Raun, Steffen Henning, Møller, Lisbeth L V, Jafari Kermani, Abbas, Ditzel, N., Andersen, Nicoline Resen, Fritzen, Andreas Mæchel, Gerhart-Hines, Zach, Kiens, Bente, Suomalainen, A., Simpson, S. J., Salling Olsen, M., Kieser, A., Schjerling, Peter, Nieminen, A. I., Richter, Erik A., Havula, E. & Sylow, Lykke, 2023, In: Science Advances. 9, 32, 18 p., eadf7119.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions

    Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, Clemmensen, Christoffer, 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Time of day determines postexercise metabolism in mouse adipose tissue

    Pendergrast, L. A., Lundell, L. S., Ehrlich, Amy M, Ashcroft, Stephen Paul, Schönke, M., Basse, A. L., Krook, A., Treebak, Jonas Thue, Dollet, L. & Zierath, Juleen R, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 8, e2218510120.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Tracing the biological roots of obesity resistance in humans

    Lund, Jens, 2023, In: Nature Reviews Endocrinology. 19, p. 500 1 p.

    Research output: Contribution to journalLetterpeer-review

  25. 2022
  26. Published

    ADRA1A–Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP

    Rahbani, J. F., Scholtes, C., Lagarde, D. M., Hussain, M. F., Roesler, A., Dykstra, C. B., Bunk, J., Samborska, B., O’Brien, S. L., Tripp, E., Pacis, A., Angueira, A. R., Johansen, O. S., Cinkornpumin, J., Hossain, I., Lynes, M. D., Zhang, Y., White, A. P., Pastor, W. A., Chondronikola, M. & 12 others, Sidossis, L., Klein, S., Kralli, A., Cypess, A. M., Pedersen, S. B., Jessen, N., Tseng, Y. H., Gerhart-Hines, Zach, Seale, P., Calebiro, D., Giguère, V. & Kazak, L., 2022, In: Nature Metabolism. 4, 11, p. 1459-1473

    Research output: Contribution to journalLetterpeer-review

  27. Published

    Acute and long-term effects of psilocybin on energy balance and feeding behavior in mice

    Fadahunsi, N., Lund, Jens, Breum, Alberte Wollesen, Mathiesen, C. V., Larsen, I. B., Knudsen, Gitte Moos, Klein, A. B. & Clemmensen, Christoffer, 2022, In: Translational Psychiatry. 12, 12 p., 330.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Fueling the fire of adipose thermogenesis

    Wolfrum, C. & Gerhart-Hines, Zach, 2022, In: Science. 375, 6586, p. 1229-1231 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration

    Pedersen, J. S., Rygg, M. O., Chrøis, K., Sustarsic, E. G., Gerhart-Hines, Zach, Wever Albrechtsen, N. J., Serizawa, R. R., Kristiansen, V. B., Basse, A. L., Boilesen, Astrid Elisabeth Bruun, Olsen, B. H., Hansen, Torben, Gluud, Lise Lotte, Madsbad, Sten, Larsen, S., Bendtsen, Flemming & Dela, Flemming, 2022, In: Nature Communications. 13, 15 p., 2931.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Leveraging GPCR signaling in thermogenic fat to counteract metabolic diseases

    Sveidahl Johansen, O., Ma, Tao & Gerhart-Hines, Zach, 2022, In: Molecular Metabolism. 60, 8 p., 101474.

    Research output: Contribution to journalReviewpeer-review

  31. Published

    Lipolysis regulates major transcriptional programs in brown adipocytes

    Markussen, L. K., Rondini, E. A., Johansen, O. S., Madsen, J. G. S., Sustarsic, E. G., Marcher, A. B., Hansen, Jacob B., Gerhart-Hines, Zach, Granneman, J. G. & Mandrup, S., 2022, In: Nature Communications. 13, 1, 16 p., 3956.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Outrunning obesity with Lac-Phe?

    Lund, Jens, Clemmensen, Christoffer & Schwartz, Thue W., 2022, In: Cell Metabolism. 34, 8, p. 1085-1087 3 p.

    Research output: Contribution to journalComment/debatepeer-review

  33. Published

    Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response

    Snieckute, Goda, Genzor Garbayo, Aitana Victoria, Vind, Anna Constance, Jordan, Laura Ryder, Stoneley, M., Chamois, S., Dreos, R., Nordgaard, C., Sass, Frederike, Blasius, Melanie, López, A. R., Brynjólfsdóttir, S. H., Andersen, Kasper Langebjerg, Willis, A. E., Frankel, Lisa, Poulsen, Steen Seier, Gatfield, D., Gerhart-Hines, Zach, Clemmensen, Christoffer & Bekker-Jensen, Simon Holst, 2022, In: Cell Metabolism. 34, 12, p. 2036-2046.e8 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance

    Klein, A. B., Nicolaisen, T. S., Johann, K., Fritzen, Andreas Mæchel, Mathiesen, C. V., Gil, Cláudia, Pilmark, N. S., Karstoft, Kristian, Blond, Martin Bæk, Quist, Jonas Salling, Seeley, R. J., Færch, K., Lund, Jens, Kleinert, Maximilian & Clemmensen, Christoffer, 2022, In: Cell Reports. 40, 8, 111258.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    The physiology of experimental overfeeding in animals

    Ranea-Robles, Pablo, Lund, Jens & Clemmensen, Christoffer, 2022, In: Molecular Metabolism. 64, 15 p., 101573.

    Research output: Contribution to journalReviewpeer-review

  36. Published

    Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling

    Segref, A., Vakkayil, K. L., Padvitski, T., Li, Q., Kroef, V., Lormann, J., Körner, L., Finger, Fabian Michael & Hoppe, T., 2022, In: Nature Communications. 13, 1, 17 p., 5874.

    Research output: Contribution to journalJournal articlepeer-review

  37. 2021
  38. Published

    TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality

    Sass, Frederike, Schlein, C., Jaeckstein, M. Y., Pertzborn, P., Schweizer, M., Schinke, T., Ballabio, A., Scheja, L., Heeren, J. & Fischer, A. W., 1 May 2021, In: Molecular Metabolism. 47, 19 p., 101173.

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting- and ghrelin-mediated food intake

    de Guia, R. M., Hassing, A. S., Ma, Tao, Plucinska, Kaja, Holst, Birgitte, Gerhart-Hines, Zach, Emanuelli, Brice & Treebak, Jonas Thue, 2021, In: F A S E B Journal. 35, 5, e21450.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men

    Soberg, S., Löfgren, J., Philipsen, F. E., Jensen, M., Hansen, Adam Espe, Ahrens, E., Nystrup, K. B., Nielsen, R. D., Solling, C., Wedell-Neergaard, A., Berntsen, M., Loft, A., Kjær, Andreas, Gerhart-Hines, Zach, Johannesen, H. H., Pedersen, Bente Klarlund, Karstoft, Kristian & Schéele, Camilla Charlotte Nielsen, 2021, In: Cell Reports Medicine. 2, 10, 23 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Cold-induction of afadin in brown fat supports its thermogenic capacity

    Lundh, M., Altıntaş, Ali, Tozzi, M., Fabre, O., Ma, Tao, Shamsi, F., Gerhart-Hines, Zach, Barrès, Romain, Tseng, Y. & Emanuelli, Brice, 2021, In: Scientific Reports. 11, 11 p., 9794.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Epidermal Acyl-CoA-binding protein is indispensable for systemic energy homeostasis

    Neess, D., Kruse, V., Marcher, A. B., Wæde, M. R., Vistisen, J., Møller, P. M., Petersen, R., Brewer, J. R., Ma, Tao, Colleluori, G., Severi, I., Cinti, S., Gerhart-Hines, Zach, Mandrup, S. & Færgeman, N. J., 2021, In: Molecular Metabolism. 44, 11 p., 101144.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

    Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, Orchard, W., Willemsen, N., Jespersen, N. Z., Lundh, M., Sustarsic, E. G., Hallgren, C. M., Frost, M., McGonigle, S., Isidor, Marie Sophie, Broholm, C., Pedersen, Oluf Borbye, Hansen, Jacob B., Grarup, Niels, Hansen, Torben, Kjær, Andreas, Granneman, J. G., Babu, M. M., Calebiro, D., Nielsen, S., Rydén, M., Soccio, R., Rensen, P. C. N., Treebak, Jonas Thue, Schwartz, Thue W., Emanuelli, Brice, Bartolomucci, A., Pfeifer, A., Zechner, R., Schéele, Camilla Charlotte Nielsen, Mandrup, S. & Gerhart-Hines, Z., 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    No effect of dietary fish oil supplementation on the recruitment of brown and brite adipocytes in mice or humans under thermoneutral conditions

    Maurer, S. F., Dieckmann, S., Lund, Jens, Fromme, T., Hess, A. L., Colson, C., Kjølbæk, Louise, Astrup, A., Gillum, M. P., Larsen, L. H., Liebisch, G., Amri, E. & Klingenspor, M., 2021, In: Molecular Nutrition & Food Research. 65, 2, 15 p., 2000681.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

    Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, Seeley, R. J., Kleinert, Maximilian, Kiens, Bente, Richter, Erik A. & Clemmensen, Christoffer, 2021, In: Nature Communications. 12, 9 p., 1041.

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment

    Rabiee, A., Plucinska, Kaja, Isidor, Marie Sophie, Brown, E. L., Tozzi, M., Sidoli, S., Petersen, P. S. S., Agueda Oyarzabal, Marina, Torsetnes, S. B., Chehabi, G. N., Lundh, M., Altıntaş, Ali, Barrès, Romain, Jensen, O. N., Gerhart-Hines, Zach & Emanuelli, Brice, 2021, In: Molecular Metabolism. 44, 17 p., 101137.

    Research output: Contribution to journalJournal articlepeer-review

  47. 2020
  48. Published

    Autocrine negative feed-back regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT

    Husted, Anna Sofie, Ekberg, J. H., Tripp, E., Nissen, T. A. D., Meijnikman, S., O'Brien, S. L., Ulven, Trond, Acherman, Y., Bruin, S. C., Nieuwdorp, M., Gerhart-Hines, Zach, Calebiro, D., Dragsted, Lars Ove & Schwartz, Thue W., 2020, In: Molecular Metabolism. 42, 10 p., 101103.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Comparative profiling of skeletal muscle models reveals heterogeneity of transcriptome and metabolism

    Abdelmoez, A. M., Puig, L. S., Smith, J. A. B., Gabriel, B. M., Savikj, M., Dollet, L., Chibalin, A. V., Krook, A., Zierath, Juleen R & Pillon, N. J., 2020, In: American Journal of Physiology: Cell Physiology. 318, 3, p. C615-C626 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells

    Møller, S. H., Mellergaard, M., Madsen, M., Bermejo, A. V., Jepsen, Stine Dam, Hansen, M. H., Høgh, R. I., Aldana, Blanca, Desler, Claus, Rasmussen, Lene Juel, Sustarsic, E. G., Gerhart-Hines, Zach, Daskalaki, E., Wheelock, C. E., Hiron, T. K., Lin, D., O'Callaghan, C. A., Wandall, Hans H., Andresen, Lars & Skov, Søren, 2020, In: Frontiers in Immunology. 11, 22 p., 1968.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus

    de Guia, R. M., Hassing, A. S., Skov, Louise Julie, Ratner, C., Plucinska, Kaja, Madsen, S., Diep, T. A., dela Cruz, Gelo, Trammell, Sam, Sustarsic, E. G., Emanuelli, Brice, Gillum, M. P., Gerhart-Hines, Zach, Holst, Birgitte & Treebak, Jonas Thue, 2020, In: Acta Physiologica. 228, 4

    Research output: Contribution to journalJournal articlepeer-review

  52. Published

    Housing temperature influences exercise training adaptations in mice

    Raun, Steffen Henning, Henriquez-Olguín, Carlos, Karavaeva, Iuliia, Ali, Mona Sadek, Møller, Lisbeth L V, Kot, Witold, Castro-Mejía, J. L., Nielsen, Dennis Sandris, Gerhart-Hines, Zach, Richter, Erik A. & Sylow, Lykke, 2020, In: Nature Communications. 11, 16 p., 1560.

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling

    Khatib-Massalha, E., Bhattacharya, S., Massalha, H., Biram, A., Golan, K., Kollet, O., Kumari, A., Avemaria, F., Petrovich-Kopitman, E., Gur-Cohen, S., Itkin, T., Brandenburger, I., Spiegel, A., Shulman, Z., Gerhart-Hines, Z., Itzkovitz, S., Gunzer, M., Offermanns, S., Alon, R., Ariel, A. & 1 others, Lapidot, T., 2020, In: Nature Communications. 11, 1, 18 p., 3547.

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    Next Generation Diabetes Scientists Shape Global Research Culture: A reflective proposal from postdoctoral researchers in diabetes research

    Gonzalez-Franquesa, A., Carrasquilla Lopez, G. D., Mamidi, A., Ghiasi, S. M., Juel, H. B., Falk, S., Isidor, M. S., Gillberg, L. M. E., Huang, L. O., Quist, J. S., Knudsen, J. R., Quaranta, R., Tozzi, M., Mikkelsen, R. B., Dall, M., Drag, M. H., Small, L. B., Altıntaş, A., Osborne, B., Modvig, I. M. & 11 others, Husted, Anna Sofie, Brown, E. L., Bak, Emilie Glad, Bastos Peluso, A. A., Finger, Fabian Michael, Grunddal, Kaare Villum, Rupar, K., Henningsen, J. B., Pedersen, M. H., Plucinska, Kaja & Attendees of the Danish Diabetes Academy Winter School 2019, A. O. T. D. D. A. W. S. 2., 2020, In: Acta Physiologica. 229, 2, 5 p., e13455.

    Research output: Contribution to journalComment/debate

  55. Published

    Role of Energy Excretion in Human Body Weight Regulation

    Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 2020, In: Trends in Endocrinology and Metabolism. 31, 10, p. 705-708 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    The unidentified hormonal defense against weight gain

    Lund, Jens, Lund, Camilla, Morville, T. H. & Clemmensen, Christoffer, 2020, In: PLOS Biology. 18, 2, 14 p., e3000629.

    Research output: Contribution to journalJournal articlepeer-review

  57. Published

    Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure

    Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, Jens, Ingerslev, L. R., Fritzen, Andreas Mæchel, Carl, Christian Strini, Lundsgaard, Anne-Marie, Frost, M., Ma, Tao, Schjerling, P., Gerhart-Hines, Zach, Flamant, F., Gauthier, K., Larsen, Steen, Richter, Erik A., Kiens, Bente & Clemmensen, Christoffer, 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  58. 2019
  59. Published

    Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue

    Lundh, M., Petersen, P. S., Isidor, Marie Sophie, Kazoka-Sørensen, D. N., Plucinska, Kaja, Shamsi, F., Ørskov, Cathrine, Tozzi, M., Brown, E. L., Andersen, E., Ma, Tao, Müller, U. A., Barrès, Romain, Kristiansen, V. B., Gerhart-Hines, Zach, Tseng, Y. & Emanuelli, Brice, 2019, In: EMBO Reports. 20, 8, e48216.

    Research output: Contribution to journalJournal articlepeer-review

  60. Published

    Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

    Deshmukh, A. S., Peijs, L., Beaudry, J. L., Jespersen, N. Z., Nielsen, C. H., Ma, T., Brunner, A. D., Larsen, T. J., Bayarri-Olmos, R., Prabhakar, B. S., Helgstrand, C., Severinsen, M. C. K., Holst, B., Kjaer, A., Tang-Christensen, M., Sanfridson, A., Garred, P., Privé, G. G., Pedersen, B. K., Gerhart-Hines, Z. & 4 others, Nielsen, S., Drucker, D. J., Mann, Matthias & Schéele, Camilla Charlotte Nielsen, 2019, In: Cell Metabolism. 30, 5, p. 963-975.e7 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  61. Published

    THU-491-The role of alanine glyoxylate aminotransferase in hepatocellular carcinoma

    Satriano, L., Lewinska, Monika, Rourke, C. O., Oliveira, D. V., Bhatt, D. K., Taranta, A., Herr, M., Straub, B., Conner, D. E. A., Budhu, D. A., Pomyen, Y., Ma, Tao, Gerhart-Hines, Zach, Stjernegaard, D. C. S., Matter, M., Crocoll, D. C., Wang, X. W., Marquardt, J. & Andersen, Jesper Bøje, 2019, p. e377.

    Research output: Contribution to conferencePosterResearch

  62. 2018
  63. Published

    NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity

    Nielsen, K. N., Peics, J., Ma, Tao, Karavaeva, Iuliia, Dall, M., Chubanava, Sabina, Basse, A. L., Dmytriyeva, O., Treebak, Jonas Thue & Gerhart-Hines, Zach, May 2018, In: Molecular Metabolism. 11, p. 178-188 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  64. Published

    Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation

    Agudelo, L. Z., Ferreira, D. M. S., Cervenka, I., Bryzgalova, G., Dadvar, S., Jannig, P. R., Pettersson-Klein, A. T., Lakshmikanth, T., Sustarsic, E. G., Porsmyr-Palmertz, M., Correia, J. C., Izadi, M., Martínez-Redondo, V., Ueland, P. M., Midttun, Ø., Gerhart-Hines, Zach, Brodin, P., Pereira, T., Berggren, P. & Ruas, J. L., 6 Feb 2018, In: Cell Metabolism. 27, 2, p. 378-392.e5

    Research output: Contribution to journalJournal articlepeer-review

  65. Published

    A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening

    van den Berg, R., Kooijman, S., Noordam, R., Ramkisoensing, A., Abreu-Vieira, G., Tambyrajah, L. L., Dijk, W., Ruppert, P., Mol, I. M., Kramar, B., Caputo, R., Puig, L. S., de Ruiter, E. M., Kroon, J., Hoekstra, M., van der Sluis, R. J., Meijer, O. C., Willems van Dijk, K., van Kerkhof, L. W. M., Christodoulides, C. & 8 others, Karpe, F., Gerhart-Hines, Zach, Kersten, S., Meijer, J. H., Coomans, C. P., van Heemst, D., Biermasz, N. R. & Rensen, P. C. N., 2018, In: Cell Reports. 22, 13, p. 3521-3533 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  66. Published

    Brown fat: the biological furnace that could burn away obesity

    Lund, Jens, Peics, J. & Gerhart-Hines, Zach, 2018, In: Biozoom. 20, 3, p. 4-6 3 p.

    Research output: Contribution to journalJournal article

  67. Published

    Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

    Sustarsic, E. G., Ma, T., Lynes, M. D., Larsen, M., Karavaeva, I., Havelund, J. F., Nielsen, C. H., Jedrychowski, M. P., Moreno-Torres, M., Lundh, M., Plucinska, K., Jespersen, N. Z., Grevengoed, T. J., Kramar, B., Peics, J., Hansen, J. B., Shamsi, F., Forss, I., Neess, D., Keipert, S. & 24 others, Wang, J., Stohlmann, K., Brandslund, I., Christensen, C., Jørgensen, M. E., Linneberg, Allan René, Pedersen, Oluf Borbye, Kiebish, M. A., Qvortrup, Klaus, Han, X., Pedersen, Bente Klarlund, Jastroch, M., Mandrup, S., Kjær, Andreas, Gygi, S. P., Hansen, Torben, Gillum, M. P., Grarup, Niels, Emanuelli, Brice, Nielsen, S., Schéele, Camilla Charlotte Nielsen, Tseng, Y., Færgeman, N. J. & Gerhart-Hines, Zach, 2018, In: Cell Metabolism. 28, 1, p. 159-174.e11

    Research output: Contribution to journalJournal articlepeer-review

  68. Published

    Cold-Activated Lipid Dynamics in Adipose Tissue Highlights a Role for Cardiolipin in Thermogenic Metabolism

    Lynes, M. D., Shamsi, F., Sustarsic, E. G., Leiria, L. O., Wang, C. H., Su, S. C., Huang, T. L., Gao, Fei, Narain, N. R., Chen, E. Y., Cypess, A. M., Schulz, T. J., Gerhart-Hines, Zach, Kiebish, M. A. & Tseng, Y. H., 2018, In: Cell Reports. 24, 3, p. 781-790 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  69. 2017
  70. Published

    Keeping fat on time: Circadian control of adipose tissue

    Ninel Hansen, S., Peics, J. & Gerhart-Hines, Zach, Nov 2017, In: Experimental Cell Research. 360, 1, p. 31-34 4 p.

    Research output: Contribution to journalReviewpeer-review

  71. Published

    Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge

    Emmett, M. J., Lim, H., Jager, J., Richter, H. J., Adlanmerini, M., Peed, L. C., Briggs, E. R., Steger, D. J., Ma, Tao, Sims, C. A., Baur, J. A., Pei, L., Won, K., Seale, P., Gerhart-Hines, Zach & Lazar, M. A., 2017, In: Nature Genetics. 546, 7659, p. 544-448

    Research output: Contribution to journalJournal articlepeer-review

  72. 2015
  73. Published

    First report on intraoperative vector flow imaging of the heart among patients with healthy and diseased aortic valves

    Hansen, Kristoffer Lindskov, Møller-Sørensen, H., Pedersen, M. M., Hansen, P. M., Kjærgaard, Jesper, Lund, Jens, Nilsson, J. C., Jensen, J. A. & Nielsen, Michael Bachmann, 1 Feb 2015, In: Ultrasonics. 56, p. 243-250 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  74. 2014
  75. Published

    Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo

    Fang, B., Everett, L. J., Jager, J., Briggs, E., Armour, S. M., Feng, D., Roy, A., Gerhart-Hines, Zach, Sun, Z. & Lazar, M. A., 20 Nov 2014, In: Cell. 159, 5, p. 1140-1152 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  76. 2013
  77. Published

    Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex

    Lim, J. H., Gerhart-Hines, Zach, Dominy, J. E., Lee, Y., Kim, S., Tabata, M., Xiang, Y. K. & Puigserver, P., 8 Mar 2013, In: Journal of Biological Chemistry. 288, 10, p. 7117-7126 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  78. Published

    Intraoperative vector flow imaging of the heart

    Hansen, Kristoffer Lindskov, Moller-Sorensen, H., Pedersen, M. M., Kjærgaard, Jesper, Nilsson, J. C., Lund, Jens, Nielsen, Michael Bachmann & Jensen, J. A., 2013, 2013 IEEE International Ultrasonics Symposium, IUS 2013. p. 1745-1748 4 p. 6725113. (IEEE International Ultrasonics Symposium, IUS).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  79. 2012
  80. Published

    A metabolic prosurvival role for PML in breast cancer

    Carracedo, A., Weiss, D., Leliaert, A. K., Bhasin, M., De Boer, V. C. J., Laurent, G., Adams, A. C., Sundvall, M., Song, S. J., Ito, K., Finley, L. S., Egia, A., Libermann, T., Gerhart-Hines, Zach, Puigserver, P., Haigis, M. C., Maratos-Flier, E., Richardson, A. L., Schafer, Z. T. & Pandolfi, P. P., 4 Sep 2012, In: Journal of Clinical Investigation. 122, 9, p. 3088-3100 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  81. 2011
  82. Published

    The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD +

    Gerhart-Hines, Zach, Dominy, J. E., Blättler, S. M., Jedrychowski, M. P., Banks, A. S., Lim, J. H., Chim, H., Gygi, S. P. & Puigserver, P., 23 Dec 2011, In: Molecular Cell. 44, 6, p. 851-863 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  83. Published

    Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming

    Dominy, J. E., Gerhart-Hines, Zach & Puigserver, P., 2011, In: Cold Spring Harbor Symposia on Quantitative Biology. 76, p. 203-209 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  84. 2010
  85. Published

    Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5

    Dominy, J. E., Lee, Y., Gerhart-Hines, Zach & Puigserver, P., Aug 2010, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1804, 8, p. 1676-1683 8 p.

    Research output: Contribution to journalReviewpeer-review

  86. 2009
  87. Published

    Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

    Schafer, Z. T., Grassian, A. R., Song, L., Jiang, Z., Gerhart-Hines, Zach, Irie, H. Y., Gao, S., Puigserver, P. & Brugge, J. S., 3 Sep 2009, In: Nature. 461, 7260, p. 109-113 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  88. Published

    AMPK regulates energy expenditure by modulating NAD + metabolism and SIRT1 activity

    Cantó, C., Gerhart-Hines, Zach, Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P. & Auwerx, J., 23 Apr 2009, In: Nature. 458, 7241, p. 1056-1060 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  89. Published

    Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells

    Suchankova, G., Nelson, L. E., Gerhart-Hines, Zach, Kelly, M., Gauthier, M. S., Saha, A. K., Ido, Y., Puigserver, P. & Ruderman, N. B., 23 Jan 2009, In: Biochemical and Biophysical Research Communications. 378, 4, p. 836-841 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  90. 2008
  91. Published

    Metabolic adaptations through the PGC-1α and SIRT1 pathways

    Rodgers, J. T., Lerin, C., Gerhart-Hines, Zach & Puigserver, P., 9 Jan 2008, In: FEBS Letters. 582, 1, p. 46-53 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  92. 2007
  93. Published

    Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α

    Gerhart-Hines, Zach, Rodgers, J. T., Bare, O., Lerin, C., Kim, S. H., Mostoslavsky, R., Alt, F. W., Wu, Z. & Puigserver, P., 4 Apr 2007, In: EMBO Journal. 26, 7, p. 1913-1923 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  94. 2006
  95. Published

    Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

    Lagouge, M., Argmann, C., Gerhart-Hines, Zach, Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., Geny, B., Laakso, M., Puigserver, P. & Auwerx, J., 15 Dec 2006, In: Cell. 127, 6, p. 1109-1122 14 p.

    Research output: Contribution to journalJournal articlepeer-review