Lowered muscle glycogen reduces body mass with no effect on short-term exercise performance in men

Research output: Contribution to journalJournal articlepeer-review

Standard

Lowered muscle glycogen reduces body mass with no effect on short-term exercise performance in men. / Schytz, Camilla Tvede; Ørtenblad, Niels; Birkholm, Thor Andersen; Plomgaard, Peter; Nybo, Lars; Kolnes, Kristoffer Jensen; Andersen, Ole Emil; Lundby, Carsten; Nielsen, Joachim; Gejl, Kasper Degn.

In: Scandinavian Journal of Medicine & Science in Sports, Vol. 33, No. 7, 2023, p. 1054-1071.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Schytz, CT, Ørtenblad, N, Birkholm, TA, Plomgaard, P, Nybo, L, Kolnes, KJ, Andersen, OE, Lundby, C, Nielsen, J & Gejl, KD 2023, 'Lowered muscle glycogen reduces body mass with no effect on short-term exercise performance in men', Scandinavian Journal of Medicine & Science in Sports, vol. 33, no. 7, pp. 1054-1071. https://doi.org/10.1111/sms.14354

APA

Schytz, C. T., Ørtenblad, N., Birkholm, T. A., Plomgaard, P., Nybo, L., Kolnes, K. J., Andersen, O. E., Lundby, C., Nielsen, J., & Gejl, K. D. (2023). Lowered muscle glycogen reduces body mass with no effect on short-term exercise performance in men. Scandinavian Journal of Medicine & Science in Sports, 33(7), 1054-1071. https://doi.org/10.1111/sms.14354

Vancouver

Schytz CT, Ørtenblad N, Birkholm TA, Plomgaard P, Nybo L, Kolnes KJ et al. Lowered muscle glycogen reduces body mass with no effect on short-term exercise performance in men. Scandinavian Journal of Medicine & Science in Sports. 2023;33(7):1054-1071. https://doi.org/10.1111/sms.14354

Author

Schytz, Camilla Tvede ; Ørtenblad, Niels ; Birkholm, Thor Andersen ; Plomgaard, Peter ; Nybo, Lars ; Kolnes, Kristoffer Jensen ; Andersen, Ole Emil ; Lundby, Carsten ; Nielsen, Joachim ; Gejl, Kasper Degn. / Lowered muscle glycogen reduces body mass with no effect on short-term exercise performance in men. In: Scandinavian Journal of Medicine & Science in Sports. 2023 ; Vol. 33, No. 7. pp. 1054-1071.

Bibtex

@article{fbaf38e126f9456b861246b1ff0df0b0,
title = "Lowered muscle glycogen reduces body mass with no effect on short-term exercise performance in men",
abstract = "Performance in short-duration sports is highly dependent on muscle glycogen, but the total degradation is only moderate and considering the water-binding property of glycogen, unnecessary storing of glycogen may cause an unfavorable increase in body mass. To investigate this, we determined the effect of manipulating dietary carbohydrates (CHO) on muscle glycogen content, body mass and short-term exercise performance. In a cross-over design twenty-two men completed two maximal cycle tests of either 1-min (n = 10) or 15-min (n = 12) duration with different pre-exercise muscle glycogen levels. Glycogen manipulation was initiated three days prior to the tests by exercise-induced glycogen-depletion followed by ingestion of a moderate (M-CHO) or high (H-CHO) CHO-diet. Subjects were weighed before each test, and muscle glycogen content was determined in biopsies from m. vastus lateralis before and after each test. Pre-exercise muscle glycogen content was lower following M-CHO than H-CHO (367 mmol · kg-1 DW vs. 525 mmol · kg-1 DW, p < 0.00001), accompanied by a 0.7 kg lower body mass (p < 0.00001). No differences were observed in performance between diets in neither the 1-min (p = 0.33) nor the 15-min (P = 0.99) test. In conclusion, pre-exercise muscle glycogen content and body mass was lower after ingesting moderate compared with high amounts of CHO, while short-term exercise performance was unaffected. This demonstrates that adjusting pre-exercise glycogen levels to the requirements of competition may provide an attractive weight management strategy in weight-bearing sports, particularly in athletes with high resting glycogen levels.",
keywords = "Faculty of Science, Diet manipulation, Taper, Weight management, Skeletal muscle, Fatigue",
author = "Schytz, {Camilla Tvede} and Niels {\O}rtenblad and Birkholm, {Thor Andersen} and Peter Plomgaard and Lars Nybo and Kolnes, {Kristoffer Jensen} and Andersen, {Ole Emil} and Carsten Lundby and Joachim Nielsen and Gejl, {Kasper Degn}",
note = "This article is protected by copyright. All rights reserved.",
year = "2023",
doi = "10.1111/sms.14354",
language = "English",
volume = "33",
pages = "1054--1071",
journal = "Scandinavian Journal of Medicine & Science in Sports",
issn = "0905-7188",
publisher = "Wiley-Blackwell",
number = "7",

}

RIS

TY - JOUR

T1 - Lowered muscle glycogen reduces body mass with no effect on short-term exercise performance in men

AU - Schytz, Camilla Tvede

AU - Ørtenblad, Niels

AU - Birkholm, Thor Andersen

AU - Plomgaard, Peter

AU - Nybo, Lars

AU - Kolnes, Kristoffer Jensen

AU - Andersen, Ole Emil

AU - Lundby, Carsten

AU - Nielsen, Joachim

AU - Gejl, Kasper Degn

N1 - This article is protected by copyright. All rights reserved.

PY - 2023

Y1 - 2023

N2 - Performance in short-duration sports is highly dependent on muscle glycogen, but the total degradation is only moderate and considering the water-binding property of glycogen, unnecessary storing of glycogen may cause an unfavorable increase in body mass. To investigate this, we determined the effect of manipulating dietary carbohydrates (CHO) on muscle glycogen content, body mass and short-term exercise performance. In a cross-over design twenty-two men completed two maximal cycle tests of either 1-min (n = 10) or 15-min (n = 12) duration with different pre-exercise muscle glycogen levels. Glycogen manipulation was initiated three days prior to the tests by exercise-induced glycogen-depletion followed by ingestion of a moderate (M-CHO) or high (H-CHO) CHO-diet. Subjects were weighed before each test, and muscle glycogen content was determined in biopsies from m. vastus lateralis before and after each test. Pre-exercise muscle glycogen content was lower following M-CHO than H-CHO (367 mmol · kg-1 DW vs. 525 mmol · kg-1 DW, p < 0.00001), accompanied by a 0.7 kg lower body mass (p < 0.00001). No differences were observed in performance between diets in neither the 1-min (p = 0.33) nor the 15-min (P = 0.99) test. In conclusion, pre-exercise muscle glycogen content and body mass was lower after ingesting moderate compared with high amounts of CHO, while short-term exercise performance was unaffected. This demonstrates that adjusting pre-exercise glycogen levels to the requirements of competition may provide an attractive weight management strategy in weight-bearing sports, particularly in athletes with high resting glycogen levels.

AB - Performance in short-duration sports is highly dependent on muscle glycogen, but the total degradation is only moderate and considering the water-binding property of glycogen, unnecessary storing of glycogen may cause an unfavorable increase in body mass. To investigate this, we determined the effect of manipulating dietary carbohydrates (CHO) on muscle glycogen content, body mass and short-term exercise performance. In a cross-over design twenty-two men completed two maximal cycle tests of either 1-min (n = 10) or 15-min (n = 12) duration with different pre-exercise muscle glycogen levels. Glycogen manipulation was initiated three days prior to the tests by exercise-induced glycogen-depletion followed by ingestion of a moderate (M-CHO) or high (H-CHO) CHO-diet. Subjects were weighed before each test, and muscle glycogen content was determined in biopsies from m. vastus lateralis before and after each test. Pre-exercise muscle glycogen content was lower following M-CHO than H-CHO (367 mmol · kg-1 DW vs. 525 mmol · kg-1 DW, p < 0.00001), accompanied by a 0.7 kg lower body mass (p < 0.00001). No differences were observed in performance between diets in neither the 1-min (p = 0.33) nor the 15-min (P = 0.99) test. In conclusion, pre-exercise muscle glycogen content and body mass was lower after ingesting moderate compared with high amounts of CHO, while short-term exercise performance was unaffected. This demonstrates that adjusting pre-exercise glycogen levels to the requirements of competition may provide an attractive weight management strategy in weight-bearing sports, particularly in athletes with high resting glycogen levels.

KW - Faculty of Science

KW - Diet manipulation

KW - Taper

KW - Weight management

KW - Skeletal muscle

KW - Fatigue

U2 - 10.1111/sms.14354

DO - 10.1111/sms.14354

M3 - Journal article

C2 - 36932633

VL - 33

SP - 1054

EP - 1071

JO - Scandinavian Journal of Medicine & Science in Sports

JF - Scandinavian Journal of Medicine & Science in Sports

SN - 0905-7188

IS - 7

ER -

ID: 339721754