PC-1 amino acid variant (K121Q) has no impact on progression of diabetic nephropathy in type 1 diabetic patients
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
PC-1 amino acid variant (K121Q) has no impact on progression of diabetic nephropathy in type 1 diabetic patients. / Jacobsen, Peter; Grarup, Niels; Tarnow, Lise; Parving, Hans-Henrik; Pedersen, Oluf.
In: Nephrology, Dialysis, Transplantation, Vol. 17, No. 8, 2002, p. 1408-12.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - PC-1 amino acid variant (K121Q) has no impact on progression of diabetic nephropathy in type 1 diabetic patients
AU - Jacobsen, Peter
AU - Grarup, Niels
AU - Tarnow, Lise
AU - Parving, Hans-Henrik
AU - Pedersen, Oluf
PY - 2002
Y1 - 2002
N2 - Recently, an amino acid variant (K121Q) in the glycoprotein PC-1 (Q allele) has been associated with faster progression of diabetic nephropathy, as estimated by calculated creatinine clearance. We tested the impact of the PC-1 (K121Q) variant on loss of glomerular filtration rate (GFR) measured by the [(51)Cr]EDTA plasma clearance technique.
AB - Recently, an amino acid variant (K121Q) in the glycoprotein PC-1 (Q allele) has been associated with faster progression of diabetic nephropathy, as estimated by calculated creatinine clearance. We tested the impact of the PC-1 (K121Q) variant on loss of glomerular filtration rate (GFR) measured by the [(51)Cr]EDTA plasma clearance technique.
KW - Adult
KW - Age of Onset
KW - Amino Acid Substitution
KW - Diabetes Mellitus, Type 1
KW - Diabetic Nephropathies
KW - Disease Progression
KW - Female
KW - Follow-Up Studies
KW - Genetic Variation
KW - Genotype
KW - Glomerular Filtration Rate
KW - Heterozygote Detection
KW - Humans
KW - Male
KW - Phosphoric Diester Hydrolases
KW - Pyrophosphatases
KW - Time Factors
M3 - Journal article
C2 - 12147787
VL - 17
SP - 1408
EP - 1412
JO - Nephrology, Dialysis, Transplantation
JF - Nephrology, Dialysis, Transplantation
SN - 0931-0509
IS - 8
ER -
ID: 38457959