Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release

Research output: Contribution to journalJournal articleResearchpeer-review

  • Trine Nielsen
  • T Sparsø
  • Grarup, Niels
  • Torben Jørgensen
  • Charlotta Holm Pisinger
  • Daniel Rinse Witte
  • T Hansen
  • Pedersen, Oluf Borbye
  • Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium
By combining multiple genome-wide association (GWA) studies and comprehensive replication efforts, 12 novel type 2 diabetes associated loci have recently been discovered. Here we evaluate the effect of lead variants of these loci on estimates of insulin release and insulin resistance derived from an oral glucose tolerance test.
Original languageEnglish
JournalDiabetologica
Volume54
Issue number5
Pages (from-to)1052-6
Number of pages5
ISSN1432-0428
DOIs
Publication statusPublished - 1 May 2011

ID: 33506165