The new donor vigilance system in Denmark reveals regional differences in adverse reactions supposedly caused by variation in the registration

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

The new donor vigilance system in Denmark reveals regional differences in adverse reactions supposedly caused by variation in the registration. / Mikkelsen, Christina; Paarup, Helene Martina; Bruun, Mie Topholm; Pedersen, Louise Ørnskov; Hasslund, Sys; Larsen, Rune; Aagaard, Bitten; Sørensen, Betina Samuelsen.

In: Vox Sanguinis, Vol. 117, No. 3, 2022, p. 321-327.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Mikkelsen, C, Paarup, HM, Bruun, MT, Pedersen, LØ, Hasslund, S, Larsen, R, Aagaard, B & Sørensen, BS 2022, 'The new donor vigilance system in Denmark reveals regional differences in adverse reactions supposedly caused by variation in the registration', Vox Sanguinis, vol. 117, no. 3, pp. 321-327. https://doi.org/10.1111/vox.13202

APA

Mikkelsen, C., Paarup, H. M., Bruun, M. T., Pedersen, L. Ø., Hasslund, S., Larsen, R., Aagaard, B., & Sørensen, B. S. (2022). The new donor vigilance system in Denmark reveals regional differences in adverse reactions supposedly caused by variation in the registration. Vox Sanguinis, 117(3), 321-327. https://doi.org/10.1111/vox.13202

Vancouver

Mikkelsen C, Paarup HM, Bruun MT, Pedersen LØ, Hasslund S, Larsen R et al. The new donor vigilance system in Denmark reveals regional differences in adverse reactions supposedly caused by variation in the registration. Vox Sanguinis. 2022;117(3):321-327. https://doi.org/10.1111/vox.13202

Author

Mikkelsen, Christina ; Paarup, Helene Martina ; Bruun, Mie Topholm ; Pedersen, Louise Ørnskov ; Hasslund, Sys ; Larsen, Rune ; Aagaard, Bitten ; Sørensen, Betina Samuelsen. / The new donor vigilance system in Denmark reveals regional differences in adverse reactions supposedly caused by variation in the registration. In: Vox Sanguinis. 2022 ; Vol. 117, No. 3. pp. 321-327.

Bibtex

@article{38979e1233d94d8994aef528bab869fd,
title = "The new donor vigilance system in Denmark reveals regional differences in adverse reactions supposedly caused by variation in the registration",
abstract = "Background and Objectives: In recent years, there has been an increased focus among blood bank professionals on the health and safety of blood donors. In 2019, the Danish Haemovigilance Committee designed a national donor vigilance system to improve the registration of adverse reactions (AR) in blood donors. The new donor vigilance system was implemented on 1 January 2020 and we here present the results from the first year of registration. Materials and Methods: AR categories, severity level and imputability score were defined based on the definitions from the International Society of Blood Transfusion, AABB and the European Commission directive 2005/61/EC, respectively. Results: Across all severity levels, AR in Danish blood donors were found to be rare (1498 per 100,000 donations). Only 0.2% of the registered reactions were classified as serious (2.7 per 100,000 donations). Large regional differences were seen in the registration of citrate reactions and haematomas. Conclusion: Significant differences across regions in what to categorize as an AR were persistent even when including a severity score in the reporting. The Danish Haemovigilance Committee will commence a national work to align the definitions but suggests that this matter is raised to an international level as part of the current work to agree upon definitions for assessment of donor AR.",
keywords = "blood collection, donor health, donors, haemovigilance",
author = "Christina Mikkelsen and Paarup, {Helene Martina} and Bruun, {Mie Topholm} and Pedersen, {Louise {\O}rnskov} and Sys Hasslund and Rune Larsen and Bitten Aagaard and S{\o}rensen, {Betina Samuelsen}",
note = "Publisher Copyright: {\textcopyright} 2021 International Society of Blood Transfusion.",
year = "2022",
doi = "10.1111/vox.13202",
language = "English",
volume = "117",
pages = "321--327",
journal = "Vox Sanguinis",
issn = "0042-9007",
publisher = "Wiley-Blackwell",
number = "3",

}

RIS

TY - JOUR

T1 - The new donor vigilance system in Denmark reveals regional differences in adverse reactions supposedly caused by variation in the registration

AU - Mikkelsen, Christina

AU - Paarup, Helene Martina

AU - Bruun, Mie Topholm

AU - Pedersen, Louise Ørnskov

AU - Hasslund, Sys

AU - Larsen, Rune

AU - Aagaard, Bitten

AU - Sørensen, Betina Samuelsen

N1 - Publisher Copyright: © 2021 International Society of Blood Transfusion.

PY - 2022

Y1 - 2022

N2 - Background and Objectives: In recent years, there has been an increased focus among blood bank professionals on the health and safety of blood donors. In 2019, the Danish Haemovigilance Committee designed a national donor vigilance system to improve the registration of adverse reactions (AR) in blood donors. The new donor vigilance system was implemented on 1 January 2020 and we here present the results from the first year of registration. Materials and Methods: AR categories, severity level and imputability score were defined based on the definitions from the International Society of Blood Transfusion, AABB and the European Commission directive 2005/61/EC, respectively. Results: Across all severity levels, AR in Danish blood donors were found to be rare (1498 per 100,000 donations). Only 0.2% of the registered reactions were classified as serious (2.7 per 100,000 donations). Large regional differences were seen in the registration of citrate reactions and haematomas. Conclusion: Significant differences across regions in what to categorize as an AR were persistent even when including a severity score in the reporting. The Danish Haemovigilance Committee will commence a national work to align the definitions but suggests that this matter is raised to an international level as part of the current work to agree upon definitions for assessment of donor AR.

AB - Background and Objectives: In recent years, there has been an increased focus among blood bank professionals on the health and safety of blood donors. In 2019, the Danish Haemovigilance Committee designed a national donor vigilance system to improve the registration of adverse reactions (AR) in blood donors. The new donor vigilance system was implemented on 1 January 2020 and we here present the results from the first year of registration. Materials and Methods: AR categories, severity level and imputability score were defined based on the definitions from the International Society of Blood Transfusion, AABB and the European Commission directive 2005/61/EC, respectively. Results: Across all severity levels, AR in Danish blood donors were found to be rare (1498 per 100,000 donations). Only 0.2% of the registered reactions were classified as serious (2.7 per 100,000 donations). Large regional differences were seen in the registration of citrate reactions and haematomas. Conclusion: Significant differences across regions in what to categorize as an AR were persistent even when including a severity score in the reporting. The Danish Haemovigilance Committee will commence a national work to align the definitions but suggests that this matter is raised to an international level as part of the current work to agree upon definitions for assessment of donor AR.

KW - blood collection

KW - donor health

KW - donors

KW - haemovigilance

U2 - 10.1111/vox.13202

DO - 10.1111/vox.13202

M3 - Journal article

C2 - 34523137

AN - SCOPUS:85114901375

VL - 117

SP - 321

EP - 327

JO - Vox Sanguinis

JF - Vox Sanguinis

SN - 0042-9007

IS - 3

ER -

ID: 280172615