Juul Holst Group

  1. 2024
  2. E-pub ahead of print
  3. Published

    An Extended Minimal Model of OGTT: estimation of α- and β-cell dysfunction, insulin resistance, and the incretin effect

    Subramanian, V., Bagger, J. I., Harihar, V., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2024, In: American Journal of Physiology - Endocrinology and Metabolism. 326, 2, p. E182-E205

    Research output: Contribution to journalJournal articlepeer-review

  4. Accepted/In press

    Counterregulatory hormone and symptom responses to hypoglycaemia in people with type 1 diabetes, insulin-treated type 2 diabetes or without diabetes: the Hypo-RESOLVE hypoglycaemic clamp study

    Fabricius, T. W., Verhulst, C. E. M., Kristensen, Peter Lommer, Holst, Jens Juul, Tack, C. J., McCrimmon, R. J., Heller, S. R., Evans, M. L., de Galan, B. E. & Pedersen-Bjergaard, Ulrik, 2024, (Accepted/In press) In: Acta Diabetologica.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Dietary impact on fasting and stimulated GLP-1 secretion in different metabolic conditions - a narrative review

    Huber, H., Schieren, A., Holst, Jens Juul & Simon, M., 2024, In: The American Journal of Clinical Nutrition. 119, 3, p. 599-627

    Research output: Contribution to journalReviewpeer-review

  6. Published

    Effect of a 6-Week Carbohydrate-Reduced High-Protein Diet on Levels of FGF21 and GDF15 in People With Type 2 Diabetes

    Richter, Michael Martin, Thomsen, M. N., Skytte, M. J., Kjeldsen, Sasha Alexandra Sampson, Samkani, A., Frystyk, J., Magkos, Faidon, Holst, Jens Juul, Madsbad, Sten, Krarup, T., Haugaard, Steen Bendix & Albrechtsen, Nicolai Jacob Wewer, 2024, In: Journal of the Endocrine Society. 8, 4, 11 p., bvae008.

    Research output: Contribution to journalJournal articlepeer-review

  7. Accepted/In press

    Effects of exogenous GIP and GLP-2 on bone turnover in individuals with type 2 diabetes

    Skov-Jeppesen, Kirsa, Christiansen, Charlotte Bayer, Hansen, L. S., Windeløv, Johanne Agerlin, Hedbäck, N., Gasbjerg, Lærke Smidt, Hindsø, M., Svane, M. S., Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2024, (Accepted/In press) In: The Journal of clinical endocrinology and metabolism.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Elucidating the glucose-lowering effect of the bile acid sequestrant sevelamer

    Nerild, H. H., Brønden, A., Haddouchi, A. E., Ellegaard, A., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Sonne, David Peick, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: Diabetes, Obesity and Metabolism. 26, 4, p. 1252-1263

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Signs of Glucagon Resistance After a Two-Week Hypercaloric Diet Intervention

    Suppli, M. P., Høgedal, A., Bagger, J. I., Chabanova, E., van Hall, Gerrit, Forman, Julie Lyng, Christensen, Mikkel Bring, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Knop, Filip Krag, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 4, p. 955–967 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Signs of a Glucose- and Insulin-Independent Gut-Bone Axis and Aberrant Bone Homeostasis in Type 1 Diabetes

    Hartmann, Bolette, Longo, M., Mathiesen, D. S., Hare, Kristine Juul, Jørgensen, Niklas Rye, Esposito, K., Deacon, Carolyn F., Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 1, p. e259-e265 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Suboptimal Weight Loss 13 Years After Roux-en-Y Gastric Bypass Is Associated with Blunted Appetite Response

    Nymo, S., Lundanes, J., Eriksen, K., Aukan, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Johnsen, G., Græslie, H., Kulseng, B., Sandvik, J. & Martins, C., 2024, In: Obesity Surgery. 34, 2, p. 592-601

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    The effect of exogenous glucagon on circulating amino acids in individuals with and without type 2 diabetes and obesity

    Grøndahl, M. F. G., Bagger, J. I., Suppli, M. P., van Hall, Gerrit, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring, Lund, A. B. & Knop, Filip Krag, 2024, In: Endocrine Connections. 13, 3, 7 p., e230516.

    Research output: Contribution to journalJournal articlepeer-review

  13. 2023
  14. Published
  15. Published

    100 years of glucagon and 100 more

    Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Cherrington, A. D., Finan, B., Gluud, Lise Lotte, Dean, E. D., Campbell, J. E., Bloom, S. R., Tan, T. M., Knop, Filip Krag & Müller, T. D., 2023, In: Diabetologia. 66, p. 1378–1394

    Research output: Contribution to journalReviewpeer-review

  16. Published

    2′-fucosyllactose alone or combined with resistant starch increases circulating short-chain fatty acids in lean men and men with prediabetes and obesity

    Canfora, E. E., Vliex, L. M. M., Wang, T., Nauta, A., Bouwman, F. G., Holst, Jens Juul, Venema, K., Zoetendal, E. G. & Blaak, E. E., 2023, In: Frontiers in Nutrition. 10, 13 p., 1200645.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Acarbose diminishes postprandial suppression of bone resorption in patients with type 2 diabetes

    Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Helsted, M. M., Hansen, L. S., Hansen, N. L., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Bone. 170, 116687.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Appetite stimulation with cannabis-based medicine and methods for assessment of glomerular filtration in older patients with medical illness: A study protocol

    Nielsen, R. L., Bornæs, O., Storgaard, I. K., Kallemose, T., Jørgensen, L. M., Jawad, B. N., Altintas, I., Juul-larsen, H. G., Tavenier, J., Durhuus, J. A., Bengaard, A. K. P., Holst, J. J., Kolko, M., Sonne, D. P., Breindahl, T., Damgaard, M., Porrini, E., Hornum, M., Andersen, O., Pedersen, M. M. & 6 others, Rasmussen, H. H., Munk, T., Lund, Trine Meldgaard, Jensen, A. P. S. L., Andersen, A. L. & Houlind, Morten Baltzer, 2023, In: Basic & Clinical Pharmacology & Toxicology. 133, 3, p. 237-253 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    Are SADI-S and BPD/DS bariatric procedures identical twins or distant relatives? – A case report

    Guimarães, M., Pereira, A. M., Pereira, S. S., Almeida, R., Lobato, C. B., Hartmann, Bolette, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2023, In: Obesity Research and Clinical Practice. 17, 2, p. 166-170

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    Butyrate and hexanoate-enriched triglycerides increase postprandrial systemic butyrate and hexanoate in men with overweight/obesity: A double-blind placebo-controlled randomized crossover trial

    van Deuren, T., Smolders, L., Hartog, A., Bouwman, F. G., Holst, Jens Juul, Venema, K., Blaak, E. E. & Canfora, E. E., 2023, In: Frontiers in Nutrition. 9, 19 p., 1066950.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Cardiovascular effects of incretins - focus on glucagon-like peptide-1 receptor agonists

    Madsbad, Sten & Holst, Jens Juul, 2023, In: Cardiovascular Research. p. 886–904 19 p.

    Research output: Contribution to journalReviewpeer-review

  22. Published

    Childhood Obesity at the Crossroads of Science and Social Justice

    Ludwig, D. S. & Holst, Jens Juul, 2023, In: JAMA. 329, 22, p. 1909-1910

    Research output: Contribution to journalEditorial

  23. Published

    Combination of exercise and GLP-1 receptor agonist treatment reduces severity of metabolic syndrome, abdominal obesity, and inflammation: a randomized controlled trial

    Sandsdal, Rasmus Michael, Juhl, C. R., Jensen, Simon Birk Kjær, Lundgren, J. R., Janus, C., Blond, Martin Bæk, Rosenkilde, M., Bogh, A. F., Gliemann, Lasse, Jensen, Jens-Erik Beck, Antoniades, C., Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Cardiovascular Diabetology. 22, 1, 12 p., 41.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Development of a glucagon sensitivity test in humans: Pilot data and the GLUSENTIC study protocol

    Kjeldsen, S. A. S., Richter, M. M., Jensen, N. J., Nilsson, M. S. D., Heinz, N., Nybing, J. D., Linden, F. H., Høgh-Schmidt, E., Boesen, M. P., Madsbad, S., Vilstrup, H., Schiødt, F. V., Møller, A., Nørgaard, K., Schmidt, S., Rashu, E. B., Gluud, L. L., Haugaard, S. B., Holst, J. J., Rungby, J. & 1 others, Albrechtsen, Nicolai Jacob Wewer, 2023, In: Peptides. 161, 10 p., 170938.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    Does glucose lowering restore GIP's effect on insulin secretion?

    Madsbad, Sten, Knop, Filip Krag & Holst, Jens Juul, 2023, In: Nutrition, Metabolism & Cardiovascular Diseases. 33, 9, p. 1817-1818

    Research output: Contribution to journalComment/debate

  26. Published

    Effects of aerobic training and semaglutide treatment on pancreatic β-cell secretory function in patients with type 2 diabetes

    Ingersen, Arthur, Schmücker, Malte, Alexandersen, C., Graungaard, B., Thorngreen, T., Borch, J., Holst, Jens Juul, Helge, Jørn Wulff & Dela, Flemming, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2798–2811

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Effects of different doses of exercise and diet-induced weight loss on beta-cell function in type 2 diabetes (DOSE-EX): a randomized clinical trial

    Legaard, G. E., Lyngbæk, M. P. P., Almdal, T. P., Karstoft, K., Bennetsen, S. L., Feineis, C. S., Nielsen, N. S., Durrer, C. G., Liebetrau, B., Nystrup, U., Østergaard, M., Thomsen, K., Trinh, B., Solomon, T. P. J., Van Hall, G., Brønd, J. C., Holst, J. J., Hartmann, B., Christensen, R., Pedersen, B. K. & 1 others, Ried-Larsen, M., 2023, In: Nature Metabolism. 5, p. 880–895

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Effects of levothyroxine substitution therapy on hunger and food intake in individuals with hypothyroidism

    Medici, B. R., Nygaard, Birte, la Cour, J. L., Krakauer, M., Brønden, A., Sonne, M. P., Holst, Jens Juul, Rehfeld, Jens Frederik, Vilsbøll, Tina, Faber, J. & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 10, 14 p., e230314.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Effects of topical corticosteroid vs. tacrolimus on insulin sensitivity and bone homeostasis in adults with atopic dermatitis - a randomized controlled study

    Gether, L., Storgaard, H., Kezic, S., Jakasa, I., Hartmann, Bolette, Skov-Jeppesen, Kirsa, Holst, Jens Juul, Pedersen, A. J., Forman, Julie Lyng, van Hall, Gerrit, Sørensen, O. E., Skov, Lone, Røpke, Mads Almose, Knop, Filip Krag & Thyssen, Jacob Pontoppidan, 2023, In: Allergy. 78, 7, p. 1964-1979 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Endogenous glucagon-like peptide (GLP)-1 as alternative for GLP-1 receptor agonists: Could this work and how?

    Smits, Mark & Holst, Jens Juul, 2023, In: Diabetes/Metabolism Research and Reviews. 39, 8, 17 p., e3699.

    Research output: Contribution to journalReviewpeer-review

  31. Published

    Endogenous incretin levels and risk of first incident cancer: a prospective cohort study

    Jujic, A., Godina, C., Belting, M., Melander, O., Holst, Jens Juul, Ahlqvist, E., Gomez, M. F., Nilsson, P. M., Jernstrom, H. & Magnusson, M., 2023, In: Scientific Reports. 13, 1, 11 p., 382.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide

    Andrikopoulos, P., Aron-Wisnewsky, J., Chakaroun, R., Myridakis, A., Forslund, S. K., Nielsen, T., Adriouch, S., Holmes, B., Chilloux, J., Vieira-Silva, S., Falony, G., Salem, J. E., Andreelli, F., Belda, E., Kieswich, J., Chechi, K., Puig-Castellvi, F., Chevalier, M., Le Chatelier, E., Olanipekun, M. T. & 83 others, Hoyles, L., Alves, R., Helft, G., Isnard, R., Køber, Lars Valeur, Coelho, L. P., Rouault, C., Gauguier, D., Goetze, Jens P. , Prifti, E., Froguel, P., Alili, R., Galijatovic, E. A. A., Barthelemy, O., Bastard, J. P., Batisse, J. P., Bel-Lassen, P., Berland, M., Bittar, R., Blottière, H., Bosquet, F., Boubrit, R., Bourron, O., Camus, M., Ciangura, C., Collet, J. P., Dietrich, A., Djebbar, M., Doré, A., pjx571, pjx571, Fezeu, L., Fromentin, S., Pons, N., Graine, M., Grünemann, C., Hartemann, A., Hartmann, Bolette, Hornbak, M., Jaqueminet, S., Jørgensen, Niklas Rye, Julienne, H., Justesen, Johanne Marie, Kammer, J., Karup, N., Kozlowski, R., Kuhn, M., Lejard, V., Letunic, I., Levenez, F., Marko, L., Martinez-Gili, L., Massey, R., Maziers, N., Moitinho-Silva, L., Montalescot, G., Neves, A. L., Le Pavin, L. P., Pousset, F., Rodriguez-Martinez, A., Schmidt, S., Schütz, T., Silva, L., Silvain, J., Svendstrup, M., Swartz, T. D., Vanduyvenboden, T., Verger, E. O., Walther, S., Zucker, J. D., Bäckhed, F., drb459, drb459, Hansen, Torben, Oppert, J. M., Blüher, M., Nielsen, J., Raes, J., Bork, P., Yaqoob, M. M., Stumvoll, M., Pedersen, Oluf Borbye, Ehrlich, S. D., Clément, K. & Dumas, M. E., 2023, In: Nature Communications. 14, 18 p., 5843.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Exercise-related hypoglycaemia induces QTc-interval prolongation in individuals with type 1 diabetes

    Hagelqvist, P. G., Andersen, A., Maytham, K. B., Andreasen, C. R., Engberg, S., Lindhardt, T. B., Faber, J., Holst, Jens Juul, Forman, Julie Lyng, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 25, 5, p. 1186-1195 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery

    Aukan, M. I., Skårvold, S., Brandsaeter, I. Ø., Rehfeld, Jens Frederik, Holst, Jens Juul, Nymo, S., Coutinho, S. & Martins, C., 2023, In: Obesity. 31, 2, p. 399-411 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Glucagon 100 years. Important, but still enigmatic

    Holst, Jens Juul, 2023, In: Peptides. 161, 6 p., 170942.

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    Glucagon-like peptide-1 receptor agonists: role in the prevention and treatment of diabetes-related cardiovascular complications

    Lubberding, Anniek Frederike, Holst, Jens Juul & Madsbad, Sten, 2023, Cardiovascular Endocrinology and Metabolism: Theory and Practice of Cardiometabolic Medicine. Elsevier, p. 365-396

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  37. Published

    Glucose metabolism, gut-brain hormones, and acromegaly treatment: an explorative single centre descriptive analysis

    Jørgensen, N. T., Erichsen, T. M., Jørgensen, M. B., Idorn, T., Feldt-Rasmussen, Bo, Holst, Jens Juul, Feldt-Rasmussen, Ulla & Klose, M., 2023, In: Pituitary. 26, p. 152–163

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Hepatic Glucose Production, Ureagenesis, and Lipolysis Quantified using the Perfused Mouse Liver Model

    Winther-Sørensen, Marie, Kemp, I. M., Bisgaard, Hanne Cathrine, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Journal of Visualized Experiments. 2023, 200, e65596.

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    Hyperglucagonaemia and amino acid alterations in individuals with type 2 diabetes and non-alcoholic fatty liver disease

    Rix, I., Johansen, M. L., Lund, A., Suppli, M. P., Chabanova, E., van Hall, Gerrit, Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Kistorp, Caroline Michaela Nervil & Knop, Filip Krag, 2023, In: Endocrine Connections. 13, 1, 11 p., e230161.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Increased Insulin Secretion and Glucose Effectiveness in Obese Patients with Type 2 Diabetes following Bariatric Surgery

    Visentin, R., Brodersen, K., Richelsen, B., Møller, N., Dalla Man, C., Pedersen, A. K., Abrahamsen, J., Holst, Jens Juul & Nielsen, M. F., 2023, In: Journal of Diabetes Research. 2023, 14 p., 127426.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published
  42. Published

    Incretin-based therapy of metabolic disease

    Holst, Jens Juul, 2023, In: Danish Medical Journal. 70, 1, A10220597.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Individuals with type 2 diabetes have higher density of small intestinal neurotensin-expressing cells

    Ferreira, F. P., Pereira, S. S., Costa, M. M., Guimarães, M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2023, In: Molecular and Cellular Biochemistry. 478, 12, p. 2779-2787

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    Insufficient sleep predicts poor weight loss maintenance after one year

    Bogh, A. F., Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Sandsdal, Rasmus Michael, Lundgren, J. R., Noer, M. H., Vu, N. Q., Fiorenza, Matteo, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Sleep. 46, 5, 12 p., zsac295.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Insulinotropic effect of endogenously secreted incretins after gastric bypass and sleeve gastrectomy

    Madsbad, Sten & Holst, Jens Juul, 2023, In: Obesity. 31, 11, p. 2723-2724 2 p.

    Research output: Contribution to journalComment/debatepeer-review

  46. Published

    Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility

    Nerild, H. H., Brønden, A., Gether, I. M., Hellmann, P. H., Baekdal, M., Gillum, M. P., Svenningsen, J. S., Hartmann, Bolette, Rathor, N., Kudiyanur Muniraju, H. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1632-1637

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Liraglutide treatment for the prevention of glucose tolerance deterioration in women with prior gestational diabetes mellitus: A 52-week randomized controlled clinical trial

    Foghsgaard, S., Vedtofte, L., Andersen, E. S., Bahne, E., Andreasen, C., Sørensen, A. L., Forman, Julie Lyng, Mathiesen, Elisabeth, Svare, J. A., Clausen, Tine Dalsgaard, Damm, Peter, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 26, 1, p. 201-214 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    Long-acting agonists of human and rodent GLP-2 receptors for studies of the physiology and pharmacological potential of the GLP-2 system

    Gadgaard, S., Windeløv, Johanne Agerlin, Schiellerup, S. P., Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, Mette, 2023, In: Biomedicine and Pharmacotherapy. 160, 13 p., 114383.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Loss of the Secretin Receptor Impairs Renal Bicarbonate Excretion and Aggravates Metabolic Alkalosis in Mice during Acute Base-Loading

    Berg, P., Jensen, T., Andersen, J. F., Svendsen, S. L., Modvig, Ida Marie, Wang, T., Frische, S., Chow, B. K. C., Malte, H., Holst, Jens Juul, Sørensen, M. V. & Leipziger, J., 2023, In: Journal of the American Society of Nephrology : JASN. 34, 8, p. 1329-1342 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Markers of Glucagon Resistance Improve With Reductions in Hepatic Steatosis and Body Weight in Type 2 Diabetes

    Kjeldsen, Sasha Alexandra Sampson, Thomsen, M. N., Skytte, M. J., Samkani, A., Richter, Michael Martin, Frystyk, J., Magkos, Faidon, Hansen, E., Thomsen, Henrik S., Holst, Jens Juul, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Journal of the Endocrine Society. 7, 11, 11 p., bvad122.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Metabolic Dysregulation in Adult Survivors of Pediatric Hematopoietic Stem Cell Transplantation: The Role of Incretins

    Vadmand, A. C., Nissen, A. A., Mathiesen, S., Ebbesen, M. S., Gerbek, T., Fridh, M. K., Sørensen, K., Hartmann, Bolette, Holst, Jens Juul & Muller, Klaus, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 2, p. 453–462

    Research output: Contribution to journalJournal articlepeer-review

  52. Published

    Neprilysin activity is increased in metabolic dysfunction-associated steatotic liver disease and normalizes after bariatric surgery or GLP-1 therapy

    Kjeldsen, S. A. S., Gluud, L. L., Werge, M. P., Pedersen, J. S., Bendtsen, F., Alexiadou, K., Tan, T., Torekov, S. S., Iepsen, E. W., Jensen, N. J., Richter, M. M., Goetze, J. P., Rungby, J., Hartmann, B., Holst, J. J., Holst, B., Holt, J., Gustafsson, F., Madsbad, S., Svane, M. S. & 2 others, Bojsen-Møller, K. N. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: iScience. 26, 11, 13 p., 108190.

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    New therapies for obesity

    Papamargaritis, D., le Roux, C. W., Holst, Jens Juul & Davies, M. J., 2023, In: Cardiovascular Research. 119, 18, p. 2825–2842

    Research output: Contribution to journalReviewpeer-review

  54. Published

    No effect of the turmeric root phenol curcumin on prednisolone-induced gluco-metabolic perturbations in men with overweight or obesity

    Hellmann, P. H., Bagger, J. I., Carlander, K. R., Hansen, K. B., Forman, Julie Lyng, Størling, J., Chabanova, E., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 4, e220334.

    Research output: Contribution to journalJournal articlepeer-review

  55. Published

    Postprandial secretion of follistatin after gastric bypass surgery and sleeve gastrectomy

    Richter, Michael Martin, Svane, M. S., Kristiansen, V. B., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Peptides. 163, 8 p., 170978.

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    Preanalytical impact on the accuracy of measurements of glucagon, GLP-1 and GIP in clinical trials

    Rasmussen, C., Richter, Michael Martin, Jensen, N. J., Heinz, N., Hartmann, Bolette, Holst, Jens Juul, Kjeldsen, Sasha Alexandra Sampson & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Scandinavian Journal of Clinical and Laboratory Investigation. 83, 8, p. 591-598

    Research output: Contribution to journalJournal articlepeer-review

  57. Published
  58. Published
  59. Published
  60. Published

    Secretion and Impact of Gut Hormones in Obesity and Diabetes

    Holst, Jens Juul, 2023, Encyclopedia of Cell Biology: Systems, Translational and Specialized Cell Aspects of Cell Biology. Bradshaw, R. A., Hart, G. W. & Stahl, P. D. (eds.). 2 ed. Elsevier, Vol. 6. p. 543-550 8 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  61. Published

    Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones

    Pedersen, K., Andersen, H., Fledelius, C., Holst, Jens Juul, Hjuler, S. T. & Kuhre, Rune Ehrenreich, 2023, In: Molecular Metabolism. 69, 101689.

    Research output: Contribution to journalJournal articlepeer-review

  62. Published

    The expanding incretin universe: from basic biology to clinical translation

    Drucker, D. J. & Holst, Jens Juul, 2023, In: Diabetologia. 66, p. 1765-1779

    Research output: Contribution to journalReviewpeer-review

  63. Published

    The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery

    Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347

    Research output: Contribution to journalJournal articlepeer-review

  64. Published

    The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide

    Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Meier, J. J., Holst, Jens Juul & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 11, p. 3079-3092

    Research output: Contribution to journalReviewpeer-review

  65. Published

    The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

    Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, J., Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.

    Research output: Contribution to journalJournal articlepeer-review

  66. Published

    Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists

    Umapathysivam, M. M., Araldi, E., Hastoy, B., Dawed, A. Y., Vatandaslar, H., Sengupta, S., Kaufmann, A., Thomsen, S., Hartmann, B., Jonsson, A. E., Kabakci, H., Thaman, S., Grarup, N., Have, C. T., Færch, K., Gjesing, A. P., Nawaz, S., Cheeseman, J., Neville, M. J., Pedersen, O. & 12 others, Walker, M., Jennison, C., Hattersley, A. T., Hansen, Torben, Karpe, F., Holst, Jens Juul, Jones, A. G., Ristow, M., McCarthy, M. I., Pearson, E. R., Stoffel, M. & Gloyn, A. L., 2023, medRxiv, 35 p.

    Research output: Working paperPreprintResearch

  67. Published

    Unravelling Effects of Rosemary (Rosmarinus officinalis L.) Extract on Hepatic Fat Accumulation and Plasma Lipid Profile in Rats Fed a High-Fat Western-Style Diet

    Madsen, S., Bak, S. Y., Yde, C. C., Jensen, H. M., Knudsen, T. A., Bæch-Laursen, C., Holst, Jens Juul, Laustsen, C. & Hedemann, M. S., 2023, In: Metabolites. 13, 9, 21 p., 974.

    Research output: Contribution to journalJournal articlepeer-review

  68. Published

    Weight loss by calorie restriction does not alter appetite-regulating gut hormone responses from perfused rat small intestine

    Gerstenberg, M. K., Andersen, Daniel Bjørklund, Torz, L., Castorena, C. M., Bookout, A. L., Hartmann, Bolette, Rehfeld, Jens Frederik, Petersen, N., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2023, In: Acta Physiologica. 238, 1, 12 p., e13947.

    Research output: Contribution to journalJournal articlepeer-review

  69. Published

    Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function

    Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Lundgren, J. R., Martinussen, C., Wiingaard, C., Knudsen, C., Frikke-Schmidt, Ruth, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Obesity. 31, 4, p. 977-989 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  70. 2022
  71. Published

    Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial

    Andersen, E., Juhl, C. R., Kjøller, E. T., Lundgren, J. R., Janus, C., Dehestani, Y., Saupstad, M., Ingerslev, L. R., Duun, O. M., Jensen, Simon Birk Kjær, Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten, Torekov, Signe Sørensen & Barrès, Romain, May 2022, In: Human Reproduction. 37, 7, p. 1414–1422 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  72. Published

    A glucose-insulin-glucagon coupled model of the isoglycemic intravenous glucose infusion experiment

    Subramanian, V., Bagger, J. I., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Frontiers in Physiology. 13, 20 p., 911616.

    Research output: Contribution to journalJournal articlepeer-review

  73. Published

    Actions of glucagon-like peptide-1 receptor ligands in the gut

    Holst, Jens Juul, Andersen, Daniel Bjørklund & Grunddal, Kaare Villum, 2022, In: British Journal of Pharmacology. 179, 4, p. 727-742

    Research output: Contribution to journalReviewpeer-review

  74. Published
  75. Published

    Acute effects of linagliptin on intact and total glucagon-like peptide-1 and gastric inhibitory polypeptide levels in insulin-dependent type 2 diabetes patients with and without moderate renal impairment

    Meier, J. J., Quast, D. R., Nauck, M. A., Schenker, N., Deacon, Carolyn F., Holst, Jens Juul, Plum-Mörschel, L. & Kapitza, C., 2022, In: Diabetes, Obesity and Metabolism. 24, 5, p. 806-815

    Research output: Contribution to journalJournal articlepeer-review

  76. Published

    Acute effects on glucose tolerance by neprilysin inhibition in patients with type 2 diabetes

    Albrechtsen, Nicolai Jacob Wewer, Møller, A., Martinussen, C., Gluud, Lise Lotte, Rashu, E. B., Richter, Michael Martin, Plomgaard, Peter Stendahl, Goetze, Jens P. , Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2022, In: Diabetes, Obesity and Metabolism. 24, 10, p. 2017-2026 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  77. Published

    Arginine-induced glucagon secretion and glucagon-induced enhancement of amino acid catabolism are not influenced by ambient glucose levels in mice

    Maruszczak, K., Rasmussen, C., Ceutz, F. R., Ørgaard, A., Elmelund, E., Richter, Michael Martin, Holst, Jens Juul, Winther-Sørensen, Marie & Albrechtsen, Nicolai Jacob Wewer, 2022, In: American Journal of Physiology - Endocrinology and Metabolism. 323, p. E207–E214

    Research output: Contribution to journalJournal articlepeer-review

  78. Published

    Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis

    Sato, S., Dyar, K. A., Treebak, J. T., Jepsen, S. L., Ehrlich, A. M., Ashcroft, S. P., Trost, K., Kunzke, T., Prade, V. M., Small, L., Basse, A. L., Schönke, M., Chen, S., Samad, M., Baldi, P., Barrès, R., Walch, A., Moritz, T., Holst, J. J., Lutter, D. & 2 others, Zierath, Juleen R & Sassone-Corsi, P., 2022, In: Cell Metabolism. 34, 2, p. 329-345.e8 26 p.

    Research output: Contribution to journalJournal articlepeer-review

  79. Published

    Colonic lactulose fermentation has no impact on glucagon-like peptide-1 and peptide-YY secretion in healthy young men

    Christiansen, Charlotte Bayer, Veedfald, Simon, Hartmann, Bolette, Gauguin, A. M., Møller, Søren, Moritz, Thomas, Madsbad, Sten & Holst, Jens Juul, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 1, p. 77-87

    Research output: Contribution to journalJournal articlepeer-review

  80. Published

    Comparable Effects of Sleeve Gastrectomy and Roux-en-Y Gastric Bypass on Basal Fuel Metabolism and Insulin Sensitivity in Individuals with Obesity and Type 2 Diabetes

    Brodersen, K., Nielsen, M. F., Richelsen, B., Lauritzen, E. S., Pahle, E., Abrahamsen, J., Hartmann, Bolette, Holst, Jens Juul & Møller, N., 2022, In: Journal of Diabetes Research. 2022, 9 p., 5476454.

    Research output: Contribution to journalJournal articlepeer-review

  81. Published
  82. Published

    Dasiglucagon Effectively Mitigates Postbariatric Postprandial Hypoglycemia: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial

    Nielsen, C. K., Øhrstrøm, C. C., Kielgast, U. L., Hansen, D. L., Hartmann, Bolette, Holst, Jens Juul, Lund, A., Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes Care. 45, 6, p. 1476–1481

    Research output: Contribution to journalJournal articlepeer-review

  83. Published

    Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes: A randomised controlled trial

    Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Chabanova, E., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Haugaard, Steen Bendix & Krarup, T., 2022, In: Diabetologia. 65, p. 506-517 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  84. Published

    Discovery of the GI Effects of GLP-1: An Historical Perspective

    Holst, Jens Juul, 2022, In: Digestive Diseases and Sciences. 67, p. 2716-2720

    Research output: Contribution to journalReviewpeer-review

  85. Published

    Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study

    Koopen, A., Witjes, J., Wortelboer, K., Majait, S., Prodan, A., Levin, E., Herrema, H., Winkelmeijer, M., Aalvink, S., Bergman, J. J. G. H. M., Havik, S., Hartmann, B., Levels, H., Bergh, P-O., van Son, J., Balvers, M., Bastos, D. M., Stroes, E., Groen, A. K., Henricsson, M. & 8 others, Kemper, E. M., Holst, Jens Juul, Strauch, C. M., Hazen, S. L., Backhed, F., De Vos, W. M., Nieuwdorp, M. & Rampanelli, E., 2022, In: Gut. 71, p. 1577-1587 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  86. Published

    Early effects of Roux-en-Y gastric bypass on dietary fatty acid absorption and metabolism in people with obesity and normal glucose tolerance

    Hindsø, M., Bojsen-Møller, K. N., Kristiansen, V. B., Holst, Jens Juul, van Hall, Gerrit & Madsbad, Sten, 2022, In: International Journal of Obesity. 46, 7, p. 1359-1365

    Research output: Contribution to journalJournal articlepeer-review

  87. Published

    Effect of 6 weeks of very low-volume high-intensity interval training on oral glucose-stimulated incretin hormone response

    Hindsø, M., Kuhlman, A. B., Dohlmann, T. L., Lund, M. T., Hartmann, Bolette, Holst, Jens Juul, Larsen, Steen & Helge, Jørn Wulff, 2022, In: European Journal of Sport Science. 22, 3, p. 381-389

    Research output: Contribution to journalJournal articlepeer-review

  88. Published

    Effect of Meal Texture on Postprandial Glucose Excursions and Gut Hormones After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy

    Hedbäck, N., Hindsø, M., Bojsen-Møller, K. N., Linddal, A. K., Jørgensen, N. B., Dirksen, C., Møller, A., Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul, Svane, M. S. & Madsbad, Sten, 2022, In: Frontiers in Nutrition. 9, 889710.

    Research output: Contribution to journalJournal articlepeer-review

  89. Published

    Effects of a Lifestyle Intervention on Bone Turnover in Persons with Type 2 Diabetes: A post hoc Analysis of the U-TURN Trial

    Abildgaard, J., Johansen, M. Y., Skov-Jeppesen, Kirsa, Andersen, L. B., Karstoft, K., Hansen, K. B., Hartmann, Bolette, Holst, Jens Juul, Pedersen, Bente Klarlund & Ried-Larsen, M., 2022, In: Medicine and Science in Sports and Exercise. 54, 1, p. 38-46

    Research output: Contribution to journalJournal articlepeer-review

  90. Published

    Effects of carbohydrate restriction on body weight and glycemic control in individuals with type 2 diabetes: A randomized controlled trial of efficacy in real-life settings

    Weber, P., Thomsen, M. N., fbg982, fbg982, Samkani, A., Carl, M. H., Astrup, A., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Madsbad, Sten, Magkos, Faidon, Krarup, T. & Haugaard, Steen Bendix, 2022, In: Nutrients. 14, 24, 12 p., 5244.

    Research output: Contribution to journalJournal articlepeer-review

  91. Published

    Effects of short-acting exenatide added three times daily to insulin therapy on bone metabolism in type 1 diabetes

    Johansen, N. J., Dejgaard, T. F., Lund, A., Schlüntz, Camilla, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Andersen, H. U. & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 2, p. 221-227

    Research output: Contribution to journalJournal articlepeer-review

  92. Published
  93. Published

    Endurance training improves GLP-1 sensitivity and glucose tolerance in overweight women

    Åkerström, T., Stolpe, Malene Norup, Widmer, R., Dejgaard, T. F., Højberg, J. M., Møller, Kirsten, Hansen, J. S., Trinh, B., Holst, Jens Juul, Thomsen, C., Pedersen, Bente Klarlund & Ellingsgaard, H., 2022, In: Journal of the Endocrine Society. 6, 9, p. 1-8 8 p., bvac111.

    Research output: Contribution to journalJournal articlepeer-review

  94. Published

    Entero-pancreatic hormone secretion, gastric emptying and glucose absorption after frequently sampled meal tests

    Veedfald, Simon, Rehfeld, Jens Frederik, van Hall, Gerrit, Svendsen, Lars Bo & Holst, Jens Juul, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 1, p. e188-e204 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  95. Published
  96. Published

    Exenatide once weekly for alcohol use disorder investigated in a randomized, placebo-controlled clinical trial

    Klausen, M. K., Jensen, M. E., Møller, M., le Dous, N., Jensen, A-M. Ø., Zeeman, V. A., Johannsen, C-F., Lee, A. M., Thomsen, G. K., Macoveanu, J., Fisher, P. M., Gillum, M. P., Jørgensen, N. R., Bergmann, M. L., Enghusen Poulsen, H., Becker, U., Holst, J. J., Benveniste, H., Volkow, N. D., Vollstädt-Klein, S. & 5 others, Miskowiak, Kamilla, Ekstrøm, Claus Thorn, Knudsen, Gitte Moos, Visboll, T. & Fink-Jensen, Anders, 2022, In: JCI insight. 19, 20 p., e159863.

    Research output: Contribution to journalJournal articlepeer-review

  97. Published

    Exploratory analysis of eating- and physical activity-related outcomes from a randomized controlled trial for weight loss maintenance with exercise and liraglutide single or combination treatment

    Jensen, Simon Birk Kjær, Janus, C., Lundgren, J. R., Juhl, C. R., Sandsdal, Rasmus Michael, Olsen, L. M., Andresen, A., Borg, S. A., Jacobsen, I. C., Finlayson, G., Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2022, In: Nature Communications. 13, 1, 11 p., 4770.

    Research output: Contribution to journalJournal articlepeer-review

  98. Published

    Expression Profile of the GLP-1 Receptor in the Gastrointestinal Tract and Pancreas in Adult Female Mice

    Grunddal, Kaare Villum, Jensen, E. P., Ørskov, Cathrine, Andersen, Daniel Bjørklund, Windeløv, Johanne Agerlin, Poulsen, Steen Seier, Rosenkilde, M. M., Knudsen, L. B., Pyke, C. & Holst, Jens Juul, 2022, In: Endocrinology. 163, 1

    Research output: Contribution to journalJournal articlepeer-review

  99. Published

    Extreme duration exercise affects old and younger men differently

    Frandsen, J., Sahl, R. E., Rømer, T., Thunestvedt Hansen, M., Nielsen, A. B., Lie-Olesen, M. M., Rasmusen, H. K., Søgaard, D., Ingersen, A., Rosenkilde, M., Westerterp, K., Holst, J. J., Andersen, J. L., Markowski, A. R., Blachnio-Zabielska, A., Clemmensen, C., Sacchetti, M., Cataldo, A., Traina, M., Larsen, S. & 2 others, Dela, Flemming & Helge, Jørn Wulff, 2022, In: Acta Physiologica. 235, 3, e13816.

    Research output: Contribution to journalJournal articlepeer-review

  100. Published

    Fiber mixture-specific effect on distal colonic fermentation and metabolic health in lean but not in prediabetic men

    Canfora, E. E., Hermes, G. D. A., Mueller, M., Bastings, J., Vaughan, E. E., van den Berg, M. A., Holst, Jens Juul, Venema, K., Zoetendal, E. G. & Blaak, E. E., 2022, In: Gut Microbes. 14, 1

    Research output: Contribution to journalJournal articlepeer-review

  101. Published

    Fortifying a meal with oyster mushroom powder beneficially affects postprandial glucagon-like peptide-1, non-esterified free fatty acids and hunger sensation in adults with impaired glucose tolerance: a double-blind randomized controlled crossover trial

    Dicks, L., Jakobs, L., Sari, M., Hambitzer, R., Ludwig, N., Simon, M., Stehle, P., Stoffel-Wagner, B., Helfrich, H., Ahlborn, J., Rühl, M., Hartmann, Bolette, Holst, Jens Juul & Ellinger, S., 2022, In: European Journal of Nutrition. 61, p. 687–701

    Research output: Contribution to journalJournal articlepeer-review

  102. Published

    Four weeks treatment with the GLP-1 receptor analogue liraglutide lowers liver fat and concomitantly circulating glucagon in individuals with overweight

    Svane, M. S., Johannesen, H. H., Hansen, Adam Espe, Martinussen, C., Bojsen-Møller, K. N., Hansen, M. L., Deacon, Carolyn F., Keller, S. H., Klausen, Thomas Levin, Loft, A., Kjær, Andreas, Löfgren, J., Madsbad, Sten, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: International Journal of Obesity. 46, 11, p. 2058–2062 8 p.

    Research output: Contribution to journalLetterpeer-review

  103. Published

    GIP affects hepatic fat and brown adipose tissue thermogenesis, but not white adipose tissue transcriptome in T1D

    Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergman, N. C., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, J., Vilsbøll, Tina, Dejgaard, T. F., Havelund, J. F., Gorshkov, V., Kjeldsen, F., Færgeman, N. J. K., Madsen, M. R., Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 12, p. 3261–3274

    Research output: Contribution to journalJournal articlepeer-review

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