Protocol to assess arteriovenous differences across the liver and hindlimb muscles in mice following treadmill exercise
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The tissue-specific release and uptake of metabolites in response to exercise is incompletely understood. Here, we detail a protocol to assess arteriovenous differences across the liver and hindlimb muscles in response to treadmill exercise in mice. We describe steps for the treadmill running of mice and the region-specific sampling of blood from the liver and hindlimb. This procedure is particularly relevant for the study of tissue-specific metabolism in response to exercise. For complete details on the use and execution of this protocol, please refer to Sato et al. (2022). 1.
|Number of pages||11|
|Publication status||Published - 2023|
Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved.