Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon
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Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon. / Haderslev, K V; Jeppesen, P B; Hartmann, B; Thulesen, J; Sorensen, H A; Graff, J; Tofteng, F; Poulsen, S S; Madsen, J L; Holst, J J; Staun, M; Mortensen, P B; Poulsen, Steen Seier.
In: Scandinavian Journal of Gastroenterology, Vol. 37, No. 4, 01.04.2002, p. 392-8.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon
AU - Haderslev, K V
AU - Jeppesen, P B
AU - Hartmann, B
AU - Thulesen, J
AU - Sorensen, H A
AU - Graff, J
AU - Tofteng, F
AU - Poulsen, S S
AU - Madsen, J L
AU - Holst, J J
AU - Staun, M
AU - Mortensen, P B
AU - Poulsen, Steen Seier
PY - 2002/4/1
Y1 - 2002/4/1
N2 - Glucagon-like peptide 2 (GLP-2) is a newly discovered intestinotrophic hormone. We have recently reported that a 5-week GLP-2 treatment improved the intestinal absorptive capacity of short-bowel patients with no colon. Additionally, GLP-2 treatment was associated with changes in body composition that included a significant increase in total body bone mass. This article describes the effect of GLP-2 on spinal and hip bone mineral density (BMD) and biochemical markers of bone turnover in these patients.
AB - Glucagon-like peptide 2 (GLP-2) is a newly discovered intestinotrophic hormone. We have recently reported that a 5-week GLP-2 treatment improved the intestinal absorptive capacity of short-bowel patients with no colon. Additionally, GLP-2 treatment was associated with changes in body composition that included a significant increase in total body bone mass. This article describes the effect of GLP-2 on spinal and hip bone mineral density (BMD) and biochemical markers of bone turnover in these patients.
KW - Absorptiometry, Photon
KW - Adult
KW - Alkaline Phosphatase
KW - Amino Acids
KW - Bone Density
KW - Bone Diseases, Metabolic
KW - Bone Remodeling
KW - Calcium
KW - Female
KW - Gastrointestinal Hormones
KW - Glucagon
KW - Glucagon-Like Peptide 2
KW - Glucagon-Like Peptides
KW - Hormones
KW - Humans
KW - Intestinal Absorption
KW - Male
KW - Middle Aged
KW - Osteocalcin
KW - Osteoporosis
KW - Parathyroid Hormone
KW - Peptides
KW - Pilot Projects
KW - Short Bowel Syndrome
KW - Vitamin D
M3 - Journal article
C2 - 11989828
VL - 37
SP - 392
EP - 398
JO - Scandinavian Journal of Gastroenterology
JF - Scandinavian Journal of Gastroenterology
SN - 0036-5521
IS - 4
ER -
ID: 33793088