Pers Group

  1. Published

    Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965

    Ahwazi, Danial, Neopane, K., Markby, G. R., Kopietz, F., Ovens, A. J., Dall, M., Hassing, A. S., Gräsle, P., Alshuweishi, Y., Treebak, Jonas Thue, Salt, I. P., Göransson, O., Zeqiraj, E., Scott, J. W. & Sakamoto, Kei, 2021, In: Biochemical Journal. 478, 15, p. 2977-2997 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  2. Published

    Hypothalamic perineuronal net assembly is required for sustained diabetes remission induced by fibroblast growth factor 1 in rats

    Alonge, K. M., Mirzadeh, Z., Scarlett, J. M., Logsdon, A. F., Brown, Jenny, Cabrales, E., Chan, C. K., Kaiyala, K. J., Bentsen, M. A., Banks, W. A., Guttman, M., Wight, T. N., Morton, G. J. & Schwartz, M. W., 2020, In: Nature Metabolism. 2, 10, p. 1025-1033 11 p.

    Research output: Contribution to journalLetterpeer-review

  3. Published

    Hypothalamic chondroitin sulfate glycosaminoglycan matrix assembly is required for sustained diabetes remission induced by fibroblast growth factor 1 in rats

    Alonge, K. M., Mirzadeh, Z., Scarlett, J. M., Logsdon, A. F., Brown, Jenny, Cabrales, E., Chan, C. K., Kaiyala, K. J., Bentsen, M. A., Banks, W. A., Guttman, M., Wight, T. N., Morton, G. J. & Schwartz, M. W., 2020, In: Glycobiology. 30, 12, p. 1032-1033 2 p.

    Research output: Contribution to journalConference abstract in journal

  4. Published

    Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

    Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., González, M. J., Gil Flores, S., Cabaleiro Fabeiro, F. J., del Río Noriega, F., Perez, F. P., Haro González, J., Orozco Diaz, G., de Diego-Otero, Y., Moreno-Küstner, B., Auburger, G., Degenhardt, F., Heilmann-Heimbach, S., Herms, S., Hoffmann, P., Frank, J., Foo, J. C. & 26 others, Treutlein, J., Witt, S. H., Cichon, S., Kogevinas, M., Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R. I., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pers, Tune H, Bækvad-Hansen, M., Pedersen, C. B., Pedersen, M. G., Hansen, C. S., Nordentoft, Merete, Werge, Thomas, Hansen, Thomas Folkmann, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, B. D. W. G. O. T. P. G. C. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2021, In: Molecular Psychiatry. 26, 4, p. 1286-1298 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission

    Bentsen, M. A., Rausch, D. M., Mirzadeh, Z., Muta, K., Scarlett, J. M., Brown, J. M., Herranz-Pérez, V., Baquero, A. F., Thompson, J., Alonge, K. M., Faber, C. L., Kaiyala, K. J., Bennett, C., Pyke, C., Ratner, C., Egerod, K. L., Holst, B., Meek, T. H., Kutlu, B., Zhang, Y. & 9 others, Sparso, T., Grove, K. L., Morton, G. J., Kornum, Birgitte Rahbek, García-Verdugo, J. M., Secher, A., Jorgensen, R., Schwartz, M. W. & Pers, Tune H, 2020, In: Nature Communications. 11, 1, 4458.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Revisiting How the Brain Senses Glucose-And Why

    Bentsen, M. A., Mirzadeh, Z. & Schwartz, M. W., 2019, In: Cell Metabolism. 29, 1, p. 11-17

    Research output: Contribution to journalReviewpeer-review

  7. Published

    Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming

    Bergmann, T., Liu, Y., Skov, J., Mogus, L., Lee, J., Pfisterer, U., Handfield, L. F., Asenjo-Martinez, A., Lisa-Vargas, I., Seemann, S. E., Lee, J. T. H., Patikas, N., Kornum, B. R., Denham, M., Hyttel, P., Witter, M. P., Gorodkin, J., Pers, T. H., Hemberg, M., Khodosevich, K. & 1 others, Hall, Vanessa Jane, 2022, In: Frontiers in Cell and Developmental Biology. 10, 976549.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    The developing Entorhinal Cortex – a cellular map

    Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  9. Published

    The developing Entorhinal cortex - a cellular map

    Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 25 Nov 2019. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  10. Published

    Uncovering the anatomical and molecular landscape of the starting point of Alzheimer’s disease in the brain

    Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  11. Published

    The developmental neurogenic niche of the Entorhinal cortex revealed by single-cell transcriptomics.

    Bergmann, T. B., Liu, Y., Lee, J., Peralvo Vidal, Juan Miguel, Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Gorodkin, Jan, Hall, Vanessa Jane & Pers, Tune H, 2018.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  12. Published

    Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

    Blokland, G. A. M., Grove, J., Chen, C. Y., Cotsapas, C., Tobet, S., Handa, R., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M. & 35 others, Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Hansen, M., Hansen, T., Li, T., Olsen, L., Bækvad-Hansen, M., Pedersen, C. B., Pedersen, M. G., Hansen, C. S., Hansen, Thomas Folkmann, Nordentoft, Merete, Werge, Thomas, Plath, N., Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, B. D. W. G. O. T. P. G. C., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium, S. D. C. A. G. O. T. P. G. C. & iPSYCH, I., 2022, In: Biological Psychiatry. 91, 1, p. 107-117

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes

    Bonàs-Guarch, S., Guindo-Martínez, M., Miguel-Escalada, I., Grarup, N., Sebastian, D., Rodriguez-Fos, E., Sánchez, F., Planas-Fèlix, M., Cortes-Sánchez, P., González, S., Timshel, P., Pers, T. H., Morgan, C. C., Moran, I., Atla, G., González, J. R., Puiggros, M., Martí, J., Andersson, E. A., Díaz, C. & 23 others, Badia, R. M., Udler, M., Leong, A., Kaur, V., Flannick, J., Jørgensen, T., Linneberg, Allan René, Jørgensen, M. E., Witte, D. R., Christensen, C., Brandslund, I., Appel, E. V., Scott, R. A., Luan, J., Langenberg, C., Wareham, N. J., Pedersen, Oluf Borbye, Zorzano, A., Florez, J. C., Hansen, Torben, Ferrer, J., Mercader, J. M. & Torrents, D., 22 Jan 2018, In: Nature Communications. 9, 14 p., 321.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

    Brown, A. A., Fernandez-Tajes, J. J., Hong, M. G., Brorsson, C. A., Koivula, R. W., Davtian, D., Dupuis, T., Sartori, A., Michalettou, T. D., Forgie, I. M., Adam, J., Allin, K. H., Caiazzo, R., Cederberg, H., De Masi, F., Elders, P. J. M., Giordano, G. N., Haid, M., Hansen, T., Hansen, T. H. & 134 others, Hattersley, A. T., Heggie, A. J., Howald, C., Jones, A. G., Kokkola, T., Laakso, M., Mahajan, A., Mari, A., McDonald, T. J., McEvoy, D., Mourby, M., Musholt, P. B., Nilsson, B., Pattou, F., Penet, D., Raverdy, V., Ridderstråle, M., Romano, L., Rutters, F., Sharma, S., Teare, H., ‘t Hart, L., Tsirigos, Konstantinos, Vangipurapu, J., drb459, drb459, Brunak, Søren, Franks, P. W., Frost, G., Grallert, H., Jablonka, B., McCarthy, M. I., Pavo, I., Pedersen, Oluf Borbye, Ruetten, H., Walker, M., Adragni, K., Allesøe, R. L. L., Artati, A. A., Arumugam, Mani, Atabaki-Pasdar, N., Baltauss, T., Banasik, Karina, Barnett, A. L., Baum, P., Bell, J. D., Beulens, J. W., Bianzano, S. B., Bizzotto, R., Bonnefond, A., Cabrelli, L., Dale, M., Dawed, A. Y., de Preville, N., Dekkers, K. F., Deshmukh, H. A., Dings, C., Donnelly, L., Dutta, A., Ehrhardt, B., pjx571, pjx571, Eriksen, R., Fan, Yong, Ferrer, J., Fitipaldi, H., Forman, A., Fritsche, A., Froguel, P., Gassenhuber, J., Gough, S., Graefe-Mody, U., Grempler, R., Groeneveld, L., Groop, L., Gudmundsdóttir, V., Gupta, R., Hennige, A. M. H., Hill, A. V., Holl, R. W., Hudson, M., Jacobsen, Ulrik Plesner, Jennison, C., Johansen, Joachim, Jonsson, Anna Elisabet, Karaderi, Tugce, Kaye, J., Kennedy, G., Klintenberg, M., Kuulasmaa, T., Lehr, T., Loftus, H., Lundgaard, Agnete Troen, Mazzoni, G., McRobert, N., McVittie, I., Nice, R., Nicolay, C., Nijpels, G., Palmer, C. N., Pedersen, H. K., Perry, M. H., Pomares-Millan, H., Prehn, C. P., Ramisch, A., Rasmussen, Simon, Robertson, N., Rodriquez, M., Sackett, P., Scherer, N., Shah, N., Sihinevich, I., Slieker, R. C., Sondertoft, N. B., Steckel-Hamann, B., Thomas, M. K., Thomas, Cecilia Engel, Thomas, E. L. L., Thorand, B., Thorne, C. E., Tillner, J., Tura, A., Uhlen, M., van Leeuwen, N., van Oort, S., Verkindt, H., Vogt, J., Wad Sackett, P. W., Wesolowska-Andersen, A., Whitcher, B., White, M. W., Adamski, J., Schwenk, J. M., Pearson, E. R., Dermitzakis, E. T. & Viñuela, A., 2023, In: Nature Communications. 14, 17 p., 5062.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Combined micro-osmotic pump infusion and intracerebroventricular injection to study FGF1 signaling pathways in the mouse brain

    Brown, Jenny, Phan, B. A., Aalling, Nadia, Morton, G. J., Schwartz, M. W. & Scarlett, J. M., 2022, In: STAR Protocols. 3, 2, 16 p., 101329.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission

    Brown, Jenny, Bentsen, M. A., Belmont-Rausch, Dylan Matthew, Phan, B. A., Wieck, D., Wasanwala, H., Matsen, M. E., Acharya, N., Richardson, N. E., Zhao, X., Zhai, P., Secher, A., Morton, G. J., Pers, Tune H, Schwartz, M. W. & Scarlett, J. M., 2021, In: iScience. 24, 9, 19 p., 102944.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Hindbrain circuits in the control of eating behaviour and energy balance

    Cheng, W., Gordian, D., Ludwig, M. Q., Pers, Tune H, Seeley, R. J. & Myers, M. G., 2022, In: Nature Metabolism. 4, 7, p. 826-835 10 p.

    Research output: Contribution to journalReviewpeer-review

  18. Published

    Multiomics signatures of type 1 diabetes with and without albuminuria

    Clos-Garcia, M., Ahluwalia, Tarun Veer Singh, Winther, S. A., Henriksen, P., Ali, M., Fan, Yong, Stankevic, Evelina, Lyu, Liwei, Vogt, J. K., Hansen, Torben, Legido-Quigley, C., Rossing, Peter & Pedersen, Oluf Borbye, 2022, In: Frontiers in Endocrinology. 13, 17 p., 1015557.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

    Coleman, J. R. I., Gaspar, H. A., Bryois, J., Byrne, E. M., Forstner, A. J., Holmans, P. A., de Leeuw, C. A., Mattheisen, M., McQuillin, A., Whitehead Pavlides, J. M., Pers, T. H., Ripke, S., Stahl, E. A., Steinberg, S., Trubetskoy, V., Trzaskowski, M., Wang, Y., Abbott, L., Abdellaoui, A., Adams, M. J. & 32 others, Adolfsson, A. N., Agerbo, E., Akil, H., Albani, D., Alliey-Rodriguez, N., Als, T. D., Andlauer, T. F. M., Anjorin, A., Antilla, V., Van der Auwera, S., Awasthi, S., Bacanu, S. A., Badner, J. A., Bækvad-Hansen, M., Barchas, J. D., Bass, N., Bauer, M., Beekman, A. T. F., Belliveau, R., Bergen, S. E., Bigdeli, T. B., Binder, E. B., Bøen, E., Hansen, C. S., Hansen, Thomas Folkmann, Krogh, Jesper, Pedersen, C. B., Pedersen, M. G., Nordentoft, Merete, Werge, Thomas, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, B. D. W. G. O. T. P. G. C. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2020, In: Biological Psychiatry. 88, 2, p. 169-184 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    Habitual sleep disturbances and migraine: a Mendelian randomization study

    Daghlas, I., Vgontzas, A., Guo, Y., Chasman, D. I., Saxena, R., Pers, Tune H & International Headache Genetics Consortium, I. H. G. C., 2020, In: Annals of Clinical and Translational Neurology. 7, 12, p. 2370-2380 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Nationwide prediction of type 2 diabetes comorbidities

    Dworzynski, P., Aasbrenn, M., Rostgaard, K., Melbye, Mads, Gerds, Thomas Alexander, Hjalgrim, H. & Pers, Tune H, 2020, In: Scientific Reports. 10, 13 p., 1776.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    5S rRNA genes in Pisum: Sequence, long range and chromosomal organization

    Ellis, T. H. N., Lee, D., Thomas, Cecilia Engel, Simpson, P. R., Cleary, W. G., Newman, Mari-Anne & Burcham, K. W. G., Oct 1988, In: MGG Molecular & General Genetics. 214, 2, p. 333-342 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    A single-cell atlas of human and mouse white adipose tissue

    Emont, M. P., Jacobs, C., Essene, A. L., Pant, D., Tenen, D., Colleluori, G., Di Vincenzo, A., Jørgensen, A. M., Dashti, H., Stefek, A., McGonagle, E., Strobel, S., Laber, S., Agrawal, S., Westcott, G. P., Kar, A., Veregge, M. L., Gulko, A., Srinivasan, H., Kramer, Z. & 18 others, De Filippis, E., Merkel, E., Ducie, J., Boyd, C. G., Gourash, W., Courcoulas, A., Lin, S. J., Lee, B. T., Morris, D., Tobias, A., Khera, A. V., Claussnitzer, M., Pers, Tune H, Giordano, A., Ashenberg, O., Regev, A., Tsai, L. T. & Rosen, E. D., 2022, In: Nature. 603, p. 926-933

    Research output: Contribution to journalJournal articlepeer-review

  24. Published
  25. Published

    GLP-1 and nicotine combination therapy engages hypothalamic and mesolimbic pathways to reverse obesity

    Falk, S., Petersen, Jonas Odgaard, Svendsen, C. S. A., Leguizamon, Cesar Ramon Romero, Jørgensen, Søren Heide, Krauth, Nathalie, Ludwig, M. Q., Jørgensen, Kathrine Lundø, Roostalu, U., Hjort-Gregersen, G. S., Nielsen, D. A. G., Ejdrup, Aske Lykke, Pers, Tune H, Dmytriyeva, O., Hecksher-Soerensen, J., Gether, Ulrik, Kohlmeier, Kristi Anne & Clemmensen, Christoffer, 2023, In: Cell Reports. 42, 5, 18 p., 112466.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice

    Fan, Y., Støving, R. K., Berreira Ibraim, S., Hyötyläinen, T., Thirion, F., Arora, T., Lyu, L., Stankevic, E., Hansen, T. H., Déchelotte, P., Sinioja, T., Ragnarsdottir, O., Pons, N., Galleron, N., Quinquis, B., Levenez, F., Roume, H., Falony, G., Vieira-Silva, S., Raes, J. & 6 others, Clausen, L., Telléus, G. K., Bäckhed, F., Oresic, M., Ehrlich, S. D. & Pedersen, Oluf Borbye, 2023, In: Nature Microbiology. 8, p. 787–802

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells

    Fardoos, R., Asowata, O. E., Herbert, N., Nyquist, S. K., Zungu, Y., Singh, A., Ngoepe, A., Mbano, I. M., Mthabela, N., Ramjit, D., Karim, F., Kuhn, W., Madela, F. G., Manzini, V. T., Anderson, F., Berger, B., Pers, Tune H, Shalek, A. K., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 16, e148920.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

    Farup, J., Just, J., de Paoli, F., Lin, L., Jensen, J. B., Billeskov, T., Roman, I. S., Cömert, C., Møller, A. B., Madaro, L., Groppa, E., Fred, R. G., Kampmann, U., Gormsen, L. C., Pedersen, S. B., Bross, P., Stevnsner, T., Eldrup, N., Pers, T. H., Rossi, F. M. V. & 2 others, Puri, P. L. & Jessen, N., 2021, In: Cell Metabolism. 33, 11, p. 2201-2214.e11

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Benchmarker: An Unbiased, Association-Data-Driven Strategy to Evaluate Gene Prioritization Algorithms

    Fine, R. S., Pers, Tune H, Amariuta, T., Raychaudhuri, S. & Hirschhorn, J. N., 2019, In: American Journal of Human Genetics. 104, 6, p. 1025-1039

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Single-cell transcriptome and cell type-specific molecular pathways of human non-alcoholic steatohepatitis

    Fred, Rikard Göran, Steen Pedersen, J., Thompson, J. J., Lee, J., Timshel, P. N., Stender, S., Rygg, M. O., Gluud, Lise Lotte, Bjerregaard Kristiansen, V., Bendtsen, Flemming, Hansen, Torben & Pers, Tune H, 2022, In: Scientific Reports. 12, 1, 13 p., 13484.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Microbiome and metabolome features of the cardiometabolic disease spectrum

    Fromentin, S., Forslund, S. K., Chechi, K., Aron-Wisnewsky, J., Chakaroun, R., Nielsen, T., Tremaroli, V., Ji, B., Prifti, E., Myridakis, A., Chilloux, J., Andrikopoulos, P., Fan, Y., Olanipekun, M. T., Alves, R., Adiouch, S., Bar, N., Talmor-Barkan, Y., Belda, E., Caesar, R. & 44 others, Coelho, L. P., Falony, G., Fellahi, S., Galan, P., Galleron, N., Helft, G., Hoyles, L., Isnard, R., Le Chatelier, E., Julienne, H., Olsson, L., Pedersen, H. K., Pons, N., Quinquis, B., Rouault, C., Roume, H., Salem, J. E., Schmidt, T. S. B., Vieira-Silva, S., Li, P., Zimmermann-Kogadeeva, M., Lewinter, C., Søndertoft, N. B., Hansen, T. H., Gauguier, D., Gøtze, J. P., Køber, Lars Valeur, Kornowski, R., drb459, drb459, Hansen, Torben, Zucker, J. D., Hercberg, S., Letunic, I., Bäckhed, F., Oppert, J. M., Nielsen, J., Raes, J., Bork, P., Stumvoll, M., Segal, E., Clément, K., Dumas, M. E., Ehrlich, S. D. & Pedersen, Oluf Borbye, 2022, In: Nature Medicine. 28, 2, p. 303-314

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Genome-wide association analyses identify variants in developmental genes associated with hypospadias

    Geller, F., Feenstra, B., Carstensen, L., Pers, Tune H, van Rooij, I. A. L. M., Korberg, I. B., Choudhry, S., Karjalainen, J. M., Schnack, T. H., Hollegaard, M. V., Feitz, W. F. J., Roeleveld, N., Hougaard, D. M., Hirschhorn, J. N., Franke, L., Baskin, L. S., Nordenskjold, A., van der Zanden, L. F. M. & Melbye, Mads, Sep 2014, In: Nature Genetics. 46, 9, p. 957-+

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    scVAE: variational auto-encoders for single-cell gene expression data

    Grønbech, Christopher Heje, Vording, M. F., Timshel, P., Sønderby, C. K., Pers, Tune H & Winther, Ole, 2020, In: Bioinformatics. 36, 16, p. 4415-4422 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Tracing the origin of adult intestinal stem cells

    Guiu, J., Hannezo, E., Yui, S., Demharter, S., Ulyanchenko, Svetlana, Maimets, Martti, Jørgensen, A., Perlman, S., Lundvall, L., Mamsen, L. S., Larsen, A., Olesen, R. H., Andersen, C. Y., Thuesen, L. L., Hare, Kristine Juul, Pers, Tune H, Khodosevich, Konstantin, Simons, B. D. & Jensen, Kim Bak, 2019, In: Nature. 570, 7759, p. 107-111

    Research output: Contribution to journalLetterpeer-review

  35. Published

    Protocol for flow cytometry-assisted single-nucleus RNA sequencing of human and mouse adipose tissue with sample multiplexing

    Gulko, A., Essene, A., Belmont-Rausch, Dylan Matthew, Veregge, M., Pant, D., Tenen, D., Kapel, Benedicte Schultz, Emont, M. P., Pers, Tune H, Rosen, E. D. & Tsai, L. T., 2024, In: STAR Protocols. 5, 1, 21 p., 102893.

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine

    Guo, Y., Rist, P. M., Daghlas, I., Giulianini, F., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M. & 32 others, Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H., Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A. P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Hrafnsdottir, M. G., Stefansson, H., Ring, S. M., Hottenga, J. J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M., Vepsäläinen, S., Malik, R., Christensen, A. F., Hansen, Thomas Folkmann, Werge, Thomas, Olesen, Jes, The International Headache Genetics Consortium, T. I. H. G. C. & the 23andMe Research Team, T. 2. R. T., 2020, In: Nature Communications. 11, 1, 3368.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia

    Harold, D., Connolly, S., Riley, B. P., Kendler, K. S., McCarthy, S. E., McCombie, W. R., Richards, A., Owen, M. J., O'Donovan, M. C., Walters, J., Donnelly, P., Bates, L., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A. & 32 others, Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Spencer, C. C. A., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Hopkins, L., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Pers, Tune H, Hansen, M., Hansen, Thomas Folkmann, Li, T., Olsen, L., Pantelis, C., Rasmussen, Henrik Berg, Werge, Thomas, Wellcome Trust Case Control Consortium 2, W. T. C. C. C. 2. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., 2019, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 3, p. 223-231 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    PAIRUP-MS: Pathway analysis and imputation to relate unknowns in profiles from mass spectrometry-based metabolite data

    Hsu, Y. H., Churchhouse, C., Pers, Tune H, Mercader, J. M., Metspalu, A., Fischer, K., Fortney, K., Morgen, E. K., Gonzalez, C., Gonzalez, M. E., Esko, T. & Hirschhorn, J. N., 2019, In: PLOS Computational Biology. 15, 1, 26 p., e1006734.

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis

    Johnsen, Cecilie Hundahl, Kotzbeck, P., Burm, Hayley Beth, Christiansen, S. H., Pedersen, Lola Julie Torz, zmw799, zmw799, Madsen, M. P., Ratner, C., Serup, A. K., Thompson, J. J., Eichmann, T. O., Pers, Tune H, Woldbye, David Paul Drucker, Piomelli, D., Kiens, Bente, Zechner, R., Skov, Louise Julie & Holst, Birgitte, 2021, In: Molecular Metabolism. 47, 16 p., 101174.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Sustained inhibition of NPY/AgRP neuronal activity by FGF1

    Hwang, E., Scarlett, J. M., Baquero, A. F., Bennett, C. M., Dong, Y., Chau, D., Brown, Jenny, Mercer, A. J., Meek, T. H., Grove, K. L., Phan, B. A. N., Morton, G. J., Williams, K. W. & Schwartz, M. W., 2022, In: JCI insight. 7, 17, 11 p., e160891.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    microRNA-based signatures obtained from endometrial fluid identify implantative endometrium

    Ibañez-Perez, J., Díaz-Nuñez, M., Clos-García, M., Lainz, L., Iglesias, M., Díez-Zapirain, M., Rabanal, A., Bárcena, L., González, M., Lozano, J. J., Marigorta, U. M., González, E., Royo, F., Aransay, A. M., Subiran, N., Matorras, R. & Falcón-Pérez, J. M., 2022, In: Human Reproduction. 37, 10, p. 2375-2391 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Isolation and characterization of muscle stem cells, fibro-adipogenic progenitors, and macrophages from human skeletal muscle biopsies

    Jensen, J. B., Møller, A. B., Just, J., Mose, M., de Paoli, F. V., Billeskov, T. B., Fred, Rikard Göran, Pers, Tune H, Pedersen, S. B., Petersen, K. K., Bjerre, M., Farup, J. & Jessen, N., 2021, In: American Journal of Physiology - Cell Physiology. 321, 2, p. C257-C268 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

    Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., Turcot, V., Auer, P. L., Fine, R. S., Guo, X., Schurmann, C., Lempradl, A., Marouli, E., Mahajan, A., Winkler, T. W., Locke, A. E., Medina-Gomez, C., Esko, T., Vedantam, S., Giri, A. & 31 others, Lo, K. S., Alfred, T., Mudgal, P., Ng, M. C. Y., Heard-Costa, N. L., Feitosa, M. F., Manning, A. K., Willems, S. M., Sivapalaratnam, S., Abecasis, G., Alam, D. S., Allison, M., Amouyel, P., Arzumanyan, Z., Balkau, B., Bork-Jensen, J., Grarup, Niels, Hansen, Torben, Jørgensen, T., Justesen, Johanne Marie, Karpe, F., Kovacs, P., Li, J., Lind, L., Linneberg, Allan René, Pedersen, Oluf Borbye, Pers, Tune H, drb459, drb459, Zhao, J. H., Loos, R. J. F. & CHD Exome+ Consortium, C. E. C., 2019, In: Nature Genetics. 51, 3, p. 452-469 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    Complement genes contribute sex-biased vulnerability in diverse disorders

    Kamitaki, N., Sekar, A., Handsaker, R. E., de Rivera, H., Tooley, K., Morris, D. L., Taylor, K. E., Whelan, C. W., Tombleson, P., Loohuis, L. M. O., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H. & 33 others, Pers, Tune H, Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Cairns, M. J., Campion, D., Hansen, M., Hansen, T., Li, T., Olsen, L., Pantelis, C., Rasmussen, H. B., Werge, Thomas, Su, Z., Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., Psychosis Endophenotypes International Consortium, P. E. I. C. & Wellcome Trust Case–Control Consortium 2, W. T. C. C. 2., 2020, In: Nature. 582, 7813, p. 577-581 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

    Karlsson Linnér, R., Biroli, P., Kong, E., Meddens, S. F. W., Wedow, R., Fontana, M. A., Lebreton, M., Tino, S. P., Abdellaoui, A., Hammerschlag, A. R., Nivard, M. G., Okbay, A., Rietveld, C. A., Timshel, P. N., Trzaskowski, M., Vlaming, R. D., Zünd, C. L., Bao, Y., Buzdugan, L., Caplin, A. H. & 31 others, Chen, C., Eibich, P., Fontanillas, P., Gonzalez, J. R., Joshi, P. K., Karhunen, V., Kleinman, A., Levin, R. Z., Lill, C. M., Meddens, G. A., Muntané, G., Sanchez-Roige, S., Rooij, F. J. V., Taskesen, E., Wu, Y., Zhang, F., Auton, A., Boardman, J. D., Clark, D. W., Conlin, A., Dolan, C. C., Fischbacher, U., Groenen, P. J. F., Harris, K. M., Hasler, G., Hofman, A., Ikram, M. A., Jain, S., Karlsson, R., Pers, Tune H & 23and Me Research Team, 2. M. R. T., 2019, In: Nature Genetics. 51, 2, p. 245-257

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

    Kilpeläinen, T. O., Carli, J. F. M., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, Å. K., Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikäinen, L-P., Eriksson, J. & 157 others, Henneman, P., Lahti, J., Tanaka, T., Luan, J., Greco M, F. D., Pasko, D., Renström, F., Willems, S. M., Mahajan, A., Rose, L. M., Guo, X., Liu, Y., Kleber, M. E., Pérusse, L., Gaunt, T., Ahluwalia, Tarun Veer Singh, Ju Sung, Y., Ramos, Y. F., Amin, N., Amuzu, A., Barroso, I., Bellis, C., Blangero, J., Buckley, B. M., Böhringer, S., I Chen, Y., de Craen, A. J. N., Crosslin, D. R., Dale, C. E., Dastani, Z., Day, F. R., Deelen, J., Delgado, G. E., Demirkan, A., Finucane, F. M., Ford, I., Garcia, M. E., Gieger, C., Gustafsson, S., Hallmans, G., Hankinson, S. E., Havulinna, A. S., Herder, C., Hernandez, D., Hicks, A. A., Hunter, D. J., Illig, T., Ingelsson, E., Ioan-Facsinay, A., Jansson, J., Jenny, N. S., Jørgensen, M. E., Jørgensen, T., Karlsson, M., Koenig, W., Kraft, P., Kwekkeboom, J., Laatikainen, T., Ladwig, K., LeDuc, C. A., Lowe, G., Lu, Y., Marques-Vidal, P., Meisinger, C., Menni, C., Morris, A. P., Myers, R. H., Männistö, S., Nalls, M. A., Paternoster, L., Peters, A., Pradhan, A. D., Rankinen, T., Rasmussen-Torvik, L. J., Rathmann, W., Rice, T. K., Brent Richards, J., Ridker, P. M., Sattar, N., Savage, D. B., Söderberg, S., Timpson, N. J., Vandenput, L., van Heemst, D., Uh, H., Vohl, M., Walker, M., Wichmann, H., Widén, E., Wood, A. R., Yao, J., Zeller, T., Zhang, Y., Meulenbelt, I., Kloppenburg, M., Astrup, A., Sørensen, Thorkild I.A., Sarzynski, M. A., Rao, D. C., Jousilahti, P., Vartiainen, E., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Kajantie, E., Osmond, C., Palotie, A., Eriksson, J. G., Heliövaara, M., Knekt, P. B., Koskinen, S., Jula, A., Perola, M., Huupponen, R. K., Viikari, J. S., Kähönen, M., Lehtimäki, T., Raitakari, O. T., Mellström, D., Lorentzon, M., Casas, J. P., Bandinelli, S., März, W., Isaacs, A., van Dijk, K. W., van Duijn, C. M., Harris, T. B., Bouchard, C., Allison, M. A., Chasman, D. I., Ohlsson, C., Lind, L., Scott, R. A., Langenberg, C., Wareham, N. J., Ferrucci, L., Frayling, T. M., Pramstaller, P. P., Borecki, I. B., Waterworth, D. M., Bergmann, S., Waeber, G., Vollenweider, P., drb459, drb459, Hansen, Torben, Pedersen, Oluf Borbye, Hu, F. B., Eline Slagboom, P., Grallert, H., Spector, T. D., Jukema, J. W., Klein, R. J., Schadt, E. E., Franks, P. W., Lindgren, C. M., Leibel, R. L. & Loos, Ruth, 2016, In: Nature Communications. 7, 14 p., 10494.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification

    Lagou, V., Jiang, L., Ulrich, A., Zudina, L., González, K. S. G., Balkhiyarova, Z., Faggian, A., Maina, J. G., Chen, S., Todorov, P. V., Sharapov, S., David, A., Marullo, L., Mägi, R., Rujan, R. M., Ahlqvist, E., Thorleifsson, G., Gao, Η., Εvangelou, Ε., Benyamin, B. & 78 others, Scott, R. A., Isaacs, A., Zhao, J. H., Willems, S. M., Johnson, T., Gieger, C., Grallert, H., Meisinger, C., Müller-Nurasyid, M., Strawbridge, R. J., Goel, A., Rybin, D., Albrecht, E., Jackson, A. U., Stringham, H. M., Corrêa, I. R., Farber-Eger, E., Steinthorsdottir, V., Uitterlinden, A. G., Munroe, P. B., Brown, M. J., Schmidberger, J., Holmen, O., Thorand, B., Hveem, K., Wilsgaard, T., Mohlke, K. L., Wang, Z., den Hoed, M., Shmeliov, A., den Hoed, M., Loos, Ruth, Kratzer, W., Haenle, M., Koenig, W., Boehm, B. O., Tan, T. M., Tomas, A., Salem, V., Barroso, I., Tuomilehto, J., Boehnke, M., Florez, J. C., Hamsten, A., Watkins, H., Njølstad, I., Wichmann, H. E., Caulfield, M. J., Khaw, K. T., van Duijn, C. M., Hofman, A., Wareham, N. J., Langenberg, C., Whitfield, J. B., Martin, N. G., Montgomery, G., Scapoli, C., Tzoulaki, I., Elliott, P., Thorsteinsdottir, U., Stefansson, K., Brittain, E. L., McCarthy, M. I., Froguel, P., Sexton, P. M., Wootten, D., Groop, L., Dupuis, J., Meigs, J. B., Deganutti, G., Demirkan, A., Pers, Tune H, Reynolds, C. A., Aulchenko, Y. S., Kaakinen, M. A., Jones, B., Prokopenko, I. & van Duijn, C. M., 2023, In: Nature Genetics. 55, 9, p. 1448-1461 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development

    Lee, J., Møller, A. F., Chae, S., Bussek-Sedzinski, Alexandra Maria, Park, T. J., Kim, Y., Lee, H. S., Pers, Tune H, Kwon, T., Sedzinski, Jakub & Natarajan, K. N., 2023, In: Science Advances. 9, 14, p. eadd5745 23 p.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published
  50. Published
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