Schéele Group

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  1. 2024
  2. Published

    Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment

    Fadahunsi, N., Petersen, J. O., Metz, S., Jakobsen, A., Mathiesen, C. V., Buch-Rasmussen, A. S., Kurgan, N. K., Larsen, J. K., Andersen, R. C., Topilko, T., Svendsen, C., Apuschkin, M., Skovbjerg, G., Schmidt, J. H., Houser, G. A., Jager, S. E., Bach, A., Deshmukh, A. S., Kilpeläinen, T. O., Strømgaard, K. & 2 others, Madsen, Kenneth Lindegaard & Clemmensen, Christoffer, 2024, In: Science Advances. 10, 9, 20 p., eadg2636.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    De-novo reconstruction and identification of transcriptional gene regulatory network modules differentiating single-cell clusters

    Oubounyt, M., Elkjaer, M. L., Laske, T., Grønning, Alexander GB, Moeller, M. J. & Baumbach, J., 2023, In: NAR Genomics and Bioinformatics. 5, 1, 17 p., lqad018.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Mycobacterium tuberculosis Requires the Outer Membrane Lipid Phthiocerol Dimycocerosate for Starvation-Induced Antibiotic Tolerance

    Block, A. M., Namugenyi, S. B., Palani, Nagendra Prasad, Brokaw, A. M., Zhang, L., Beckman, K. B. & Tischler, A. D., 2023, In: mSystems. 8, 1, 19 p., e0069922.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Adipogenic and SWAT cells separate from a common progenitor in human brown and white adipose depots

    Palani, Nagendra Prasad, Horvath, C., Timshel, P. N., Folkertsma, P., Grønning, Alexander GB, Henriksen, T. I., Peijs, Lone, Jensen, V. H., Sun, W., Jespersen, N. Z., Wolfrum, C., Pers, Tune H, Nielsen, S. & Schéele, Camilla Charlotte Nielsen, 2023, In: Nature Metabolism. 5, 6, p. 996-1013 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. 2022
  8. Published

    Can we target obesity using a single-cell atlas of adipose tissue?

    Schéele, Camilla Charlotte Nielsen & Nielsen, S., 2022, In: Med. 3, 5, p. 276-278 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  9. Published

    Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity

    Hayashi, Y., Shimizu, I., Yoshida, Y., Ikegami, R., Suda, M., Katsuumi, G., Fujiki, S., Ozaki, K., Abe, M., Sakimura, K., Okuda, S., Hayano, T., Nakamura, K., Walsh, K., Jespersen, N. Z., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Minamino, T., 2022, In: iScience. 25, 7, 23 p., 104547.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Himalayan bacterial endophytes enhance microalgal cell numbers and chlorophyll content in synthetic co-culture

    Sonowal, S., Palani, Nagendra Prasad, Ahmed, R., Debbarma, J., Chikkaputtaiah, C., Basar, E. & Velmurugan, N., 2022, In: Journal of Applied Phycology. 34, 5, p. 2383-2400

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Human visceral and subcutaneous adipose stem and progenitor cells retain depot-specific adipogenic properties during obesity

    Mathur, N., Severinsen, M. C. K., Jensen, M. E., Naver, L., Schrölkamp, Maren, Laye, M. J., Watt, M. J., Nielsen, S., Krogh-Madsen, Rikke, Pedersen, Bente Klarlund & Schéele, Camilla Charlotte Nielsen, 2022, In: Frontiers in Cell and Developmental Biology. 10, 12 p., 983899.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Isolation and Characterization of Human Brown Adipocytes

    Schéele, Camilla Charlotte Nielsen, Henriksen, T. I. & Nielsen, S., 2022, In: Methods in Molecular Biology. 2448, p. 217-234 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    PRDM16 stability and metabolically healthy adipose tissue

    Horvath, C. & Schéele, Camilla Charlotte Nielsen, 2022, In: Nature Metabolism. 4, p. 1095-1096

    Research output: Contribution to journal › Comment/debate › Research

  14. Published

    The human batokine EPDR1 regulates β-cell metabolism and function

    Cataldo Bascunan, Luis Rodrigo, Gao, Q., Argemi Muntadas, Lidia, Hodek, O., Cowan, E., Hladkou, S., Gheibi, S., Spegel, P., Prasad, R. B., Eliasson, L., Schéele, Camilla Charlotte Nielsen, Fex, M., Mulder, H. & Moritz, Thomas, 2022, In: Molecular Metabolism. 66, 14 p., 101629.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. 2021
  16. Published

    Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men

    Soberg, S., Löfgren, J., Philipsen, F. E., Jensen, M., Hansen, Adam Espe, Ahrens, E., Nystrup, K. B., Nielsen, R. D., Solling, C., Wedell-Neergaard, A., Berntsen, M., Loft, A., Kjær, Andreas, Gerhart-Hines, Zach, Johannesen, H. H., Pedersen, Bente Klarlund, Karstoft, Kristian & Schéele, Camilla Charlotte Nielsen, 2021, In: Cell Reports Medicine. 2, 10, 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Brown Adipose Tissue: A Metabolic Regulator in a Hypothalamic Cross Talk?

    Henningsen, J. B. & Schéele, Camilla Charlotte Nielsen, 2021, In: Annual Review of Physiology. 83, p. 279-301 23 p.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Challenges in tackling energy expenditure as obesity therapy: From preclinical models to clinical application

    Löffler, M. C., Betz, M. J., Blondin, D. P., Augustin, R., Sharma, A. K., Tseng, Y. H., Schéele, Camilla Charlotte Nielsen, Zimdahl, H., Mark, M., Hennige, A. M., Wolfrum, C., Langhans, W., Hamilton, B. S. & Neubauer, H., 2021, In: Molecular Metabolism. 51, 15 p., 101237.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training

    Deshmukh, Atul Shahaji, Steenberg, D. E., Hostrup, Morten, Birk, Jesper Bratz, Larsen, Jeppe Kjærgaard, Santos, A., Kjøbsted, Rasmus, Hingst, J. R., Schéele, Camilla Charlotte Nielsen, Murgia, M., Kiens, Bente, Richter, Erik A., Mann, Matthias & Wojtaszewski, Jørgen F P, 2021, In: Nature Communications. 12, 15 p., 304.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Effects of excitotoxicity in the hypothalamus in transgenic mouse models of Huntington disease

    Henningsen, J. B., Soylu-Kucharz, R., Bjorkqvist, M. & Petersen, Å., 2021, In: Heliyon. 7, 8, 9 p., 07808.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Enabling single-cell trajectory network enrichment

    Grønning, Alexander GB, Oubounyt, M., Kanev, K., Lund, J., Kacprowski, T., Zehn, D., Röttger, R. & Baumbach, J., 2021, In: Nature Computational Science. 1, 2, p. 153-163

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution

    Schlein, C., Fischer, A. W., Sass, F., Worthmann, A., Tödter, K., Jaeckstein, M. Y., Behrens, J., Lynes, M. D., Kiebish, M. A., Narain, N. R., Bussberg, V., Darkwah, A., Jespersen, N. Z., Nielsen, S., Scheele, C., Schweizer, M., Braren, I., Bartelt, A., Tseng, Y. H., Heeren, J. & 1 others, Scheja, L., 2021, In: Cell Reports. 34, 2, 19 p., 108624.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Functional diversity of human adipose tissue revealed by spatial mapping

    Schéele, Camilla Charlotte Nielsen & Wolfrum, C., 2021, In: Nature Reviews Endocrinology. 17, p. 713-714 2 p.

    Research output: Contribution to journal › Editorial › Research

  24. Published

    Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

    Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, Orchard, W., Willemsen, N., Jespersen, N. Z., Lundh, M., Sustarsic, E. G., Hallgren, C. M., Frost, M., McGonigle, S., Isidor, Marie Sophie, Broholm, C., Pedersen, Oluf Borbye, Hansen, Jacob B., Grarup, Niels, Hansen, Torben, Kjær, Andreas, Granneman, J. G., Babu, M. M., Calebiro, D., Nielsen, S., Rydén, M., Soccio, R., Rensen, P. C. N., Treebak, Jonas Thue, Schwartz, Thue W., Emanuelli, Brice, Bartolomucci, A., Pfeifer, A., Zechner, R., Schéele, Camilla Charlotte Nielsen, Mandrup, S. & Gerhart-Hines, Z., 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    MultiPep: a hierarchical deep learning approach for multi-label classification of peptide bioactivities

    Grønning, Alexander GB, Kacprowski, T. & Schéele, Camilla Charlotte Nielsen, 2021, In: Biology Methods and Protocols. 6, 1, 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Perspectives on the role of brown adipose tissue in human body temperature and metabolism

    Schéele, Camilla Charlotte Nielsen, 2021, In: Cell Reports Medicine. 2, 10, 3 p., 100427.

    Research output: Contribution to journal › Editorial › Research

  27. Published

    Transient postprandial increase in intact circulating fibroblast growth factor-21 levels after Roux-en-Y gastric bypass: A randomized controlled clinical trial

    Nielsen, M. S., Søberg, S., Schmidt, J. B., Chenchar, A., Sjödin, Anders Mikael & Gillum, M. P., 2021, In: PeerJ. 9, 14 p., e11174.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics

    Davegårdh, C., Säll, J., Benrick, A., Broholm, C., Volkov, P., Perfilyev, A., Henriksen, T. I., Wu, Y., Hjort, L., Brøns, C., Hansson, O., Pedersen, M., Würthner, J. U., Pfeffer, K., Nilsson, E., Vaag, Allan, Stener-Victorin, E., Pircs, K., Schéele, Camilla Charlotte Nielsen & Ling, C., 2021, In: Nature Communications. 12, 1, 20 p., 2431.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. 2020
  30. Published

    Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity

    Gnad, T., Navarro, G., Lahesmaa, M., Reverte-Salisa, L., Copperi, F., Cordomi, A., Naumann, J., Hochhaeuser, A., Haufs-Brusberg, S., Wenzel, D., Suhr, F., Jespersen, N. Z., Scheele, C., Tsvilovskyy, V., Brinkmann, C., Rittweger, J., Dani, C., Kranz, M., Deuther-Conrad, W., Eltzschig, H. K. & 11 others, Niemi, T., Taittonen, M., Brust, P., Nuutila, P., Pardo, L., Fleischmann, B. K., Blueher, M., Franco, R., Bloch, W., Virtanen, K. A. & Pfeifer, A., 2020, In: Cell Metabolism. 32, 1, p. 56-70.e7 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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