Zierath Group

  1. 2024
  2. Published

    Dietary fatty acid composition drives neuroinflammation and impaired behavior in obesity

    Sanchez, C., Colson, C., Gautier, N., Noser, P., Salvi, J., Villet, M., Fleuriot, L., Peltier, C., Schlich, P., Brau, F., Sharif, A., Altıntaş, Ali, Amri, E. Z., Nahon, J. L., Blondeau, N., Benani, A., Barrès, Romain & Rovère, C., 2024, In: Brain, Behavior, and Immunity. 117, p. 330-346 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Exercise induces tissue-specific adaptations to enhance cardiometabolic health

    Ashcroft, Stephen Paul, Stocks, Ben Nicholas, Egan, B. & Zierath, Juleen R, 2024, In: Cell Metabolism. 36, 2, p. 278-300

    Research output: Contribution to journalReviewpeer-review

  4. Published

    Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M

    Dollet, L., Lundell, L. S., Chibalin, A. V., Pendergrast, L. A., Pillon, N. J., Lansbury, Elizabeth Laura, Elmastas, M., Frendo-Cumbo, S., Jalkanen, J., de Castro Barbosa, T., Cervone, D. T., Caidahl, K., Dmytriyeva, O., Deshmukh, Atul Shahaji, Barrès, Romain, Rydén, M., Wallberg-Henriksson, H., Zierath, Juleen R & Krook, A., 2024, In: Cell Reports Medicine. 5, 1, 20 p., 101348.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Mass spectrometry-based proteomics approaches to interrogate skeletal muscle adaptations to exercise

    Cervone, D. T., Moreno Justicia, Roger, Prats Quesada, Júlia & Deshmukh, Atul Shahaji, 2024, In: Scandinavian Journal of Medicine and Science in Sports. 34, 1, 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    The use of a systems approach to increase NAD+ in human participants

    Henderson, John David, Quigley, S. N. Z., Chachra, S. S., Conlon, N. & Ford, D., 2024, In: npj Aging. 10, 12 p., 7.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia

    Membrez, M., Migliavacca, E., Christen, S., Yaku, K., Trieu, J., Lee, A. K., Morandini, F., Giner, M. P., Stiner, J., Makarov, M. V., Garratt, E. S., Vasiloglou, M. F., Chanvillard, L., Dalbram, E., Ehrlich, A. M., Sanchez-Garcia, J. L., Canto, C., Karagounis, L. G., Treebak, J. T., Migaud, M. E. & 15 others, Heshmat, R., Razi, F., Karnani, N., Ostovar, A., Farzadfar, F., Tay, S. K. H., Sanders, M. J., Lillycrop, K. A., Godfrey, K. M., Nakagawa, T., Moco, S., Koopman, R., Lynch, G. S., Sorrentino, V. & Feige, J. N., 2024, In: Nature Metabolism. 6, p. 433–447

    Research output: Contribution to journalLetterpeer-review

  8. 2023
  9. Published

    Exercise metabolism and adaptation in skeletal muscle

    Smith, J. A. B., Murach, K. A., Dyar, K. A. & Zierath, Juleen R, 2023, In: Nature Reviews Molecular Cell Biology. 24, p. 607-632

    Research output: Contribution to journalReviewpeer-review

  10. Published

    Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

    Brown, A. A., Fernandez-Tajes, J. J., Hong, M. G., Brorsson, C. A., Koivula, R. W., Davtian, D., Dupuis, T., Sartori, A., Michalettou, T. D., Forgie, I. M., Adam, J., Allin, K. H., Caiazzo, R., Cederberg, H., De Masi, F., Elders, P. J. M., Giordano, G. N., Haid, M., Hansen, T., Hansen, T. H. & 134 others, Hattersley, A. T., Heggie, A. J., Howald, C., Jones, A. G., Kokkola, T., Laakso, M., Mahajan, A., Mari, A., McDonald, T. J., McEvoy, D., Mourby, M., Musholt, P. B., Nilsson, B., Pattou, F., Penet, D., Raverdy, V., Ridderstråle, M., Romano, L., Rutters, F., Sharma, S., Teare, H., ‘t Hart, L., Tsirigos, Konstantinos, Vangipurapu, J., drb459, drb459, Brunak, Søren, Franks, P. W., Frost, G., Grallert, H., Jablonka, B., McCarthy, M. I., Pavo, I., Pedersen, Oluf Borbye, Ruetten, H., Walker, M., Adragni, K., Allesøe, R. L. L., Artati, A. A., Arumugam, Mani, Atabaki-Pasdar, N., Baltauss, T., Banasik, Karina, Barnett, A. L., Baum, P., Bell, J. D., Beulens, J. W., Bianzano, S. B., Bizzotto, R., Bonnefond, A., Cabrelli, L., Dale, M., Dawed, A. Y., de Preville, N., Dekkers, K. F., Deshmukh, H. A., Dings, C., Donnelly, L., Dutta, A., Ehrhardt, B., pjx571, pjx571, Eriksen, R., Fan, Yong, Ferrer, J., Fitipaldi, H., Forman, A., Fritsche, A., Froguel, P., Gassenhuber, J., Gough, S., Graefe-Mody, U., Grempler, R., Groeneveld, L., Groop, L., Gudmundsdóttir, V., Gupta, R., Hennige, A. M. H., Hill, A. V., Holl, R. W., Hudson, M., Jacobsen, Ulrik Plesner, Jennison, C., Johansen, Joachim, Jonsson, Anna Elisabet, Karaderi, Tugce, Kaye, J., Kennedy, G., Klintenberg, M., Kuulasmaa, T., Lehr, T., Loftus, H., Lundgaard, Agnete Troen, Mazzoni, G., McRobert, N., McVittie, I., Nice, R., Nicolay, C., Nijpels, G., Palmer, C. N., Pedersen, H. K., Perry, M. H., Pomares-Millan, H., Prehn, C. P., Ramisch, A., Rasmussen, Simon, Robertson, N., Rodriquez, M., Sackett, P., Scherer, N., Shah, N., Sihinevich, I., Slieker, R. C., Sondertoft, N. B., Steckel-Hamann, B., Thomas, M. K., Thomas, Cecilia Engel, Thomas, E. L. L., Thorand, B., Thorne, C. E., Tillner, J., Tura, A., Uhlen, M., van Leeuwen, N., van Oort, S., Verkindt, H., Vogt, J., Wad Sackett, P. W., Wesolowska-Andersen, A., Whitcher, B., White, M. W., Adamski, J., Schwenk, J. M., Pearson, E. R., Dermitzakis, E. T. & Viñuela, A., 2023, In: Nature Communications. 14, 17 p., 5062.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner

    Basse, A. L., Nielsen, K. N., Karavaeva, Iuliia, Ingerslev, L. R., Ma, Tao, Havelund, J. F., Nielsen, Thomas Svava, Frost, M., Peics, J., Kellezi, Emilie Dalbram, Dall, M., Zierath, Juleen R, Barrès, Romain, Færgeman, N. J., Treebak, Jonas Thue & Gerhart-Hines, Zach, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2220102120.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published
  13. Published

    Seasonal light hours modulate peripheral clocks and energy metabolism in mice

    Small, Lewin Barkla, Lundell, L. S., Iversen, Jo Frøkjær, Ehrlich, Amy M, Dall, M., Basse, A. L., Kellezi, Emilie Dalbram, Hansen, Ann Normann, Treebak, Jonas Thue, Barrès, Romain & Zierath, Juleen R, 2023, In: Cell Metabolism. 35, 10, p. 1722-1735.e5 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published
  15. Published

    Time of day determines postexercise metabolism in mouse adipose tissue

    Pendergrast, L. A., Lundell, L. S., Ehrlich, Amy M, Ashcroft, Stephen Paul, Schönke, M., Basse, A. L., Krook, A., Treebak, Jonas Thue, Dollet, L. & Zierath, Juleen R, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 8, e2218510120.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Transient changes to metabolic homeostasis initiate mitochondrial adaptation to endurance exercise

    Dent, J. R., Stocks, Ben Nicholas, Campelj, D. G. & Philp, A., 2023, In: Seminars in Cell and Developmental Biology. 143, p. 3-16

    Research output: Contribution to journalReviewpeer-review

  17. 2022
  18. Published

    Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis

    Sato, S., Dyar, K. A., Treebak, J. T., Jepsen, S. L., Ehrlich, A. M., Ashcroft, S. P., Trost, K., Kunzke, T., Prade, V. M., Small, L., Basse, A. L., Schönke, M., Chen, S., Samad, M., Baldi, P., Barrès, R., Walch, A., Moritz, T., Holst, J. J., Lutter, D. & 2 others, Zierath, Juleen R & Sassone-Corsi, P., 2022, In: Cell Metabolism. 34, 2, p. 329-345.e8 26 p.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published
  20. Published

    Comparative analysis of sperm DNA methylation supports evolutionary acquired epigenetic plasticity for organ speciation

    Moharrek, Farideh, Ingerslev, L. R., Altıntaş, Ali, Lundell, L., Hansen, Ann Normann, Small, Lewin Barkla, Workman, C. T. & Barrès, Romain, 2022, In: Epigenomics. 14, 21, p. 1305-1324 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Deciphering inhibitory activity of flavonoids against tau protein kinases: a coupled molecular docking and quantum chemical study

    Rasouli, H., Hosseini Ghazvini, S. M. B., Yarani, R., Altıntaş, Ali, Jooneghani, S. G. N. & Ramalho, T. C., 2022, In: Journal of Biomolecular Structure & Dynamics. 40, 1, p. 411-424 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Dynamic interplay between Afadin S1795 phosphorylation and diet regulates glucose homeostasis in obese mice

    Tozzi, M., Brown, E. L., Petersen, P. S., Lundh, M., Isidor, Marie Sophie, Plucinska, Kaja, Nielsen, Thomas Svava, Agueda Oyarzabal, Marina, Small, Lewin Barkla, Treebak, Jonas Thue & Emanuelli, Brice, 2022, In: The Journal of Physiology. 600, 4, p. 885-902

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Exercise timing influences multi-tissue metabolome and skeletal muscle proteome profiles in type 2 diabetic patients - A randomized crossover trial

    Savikj, M., Stocks, Ben Nicholas, Sato, S., Caidahl, K., Krook, A., Deshmukh, Atul Shahaji, Zierath, Juleen R & Wallberg-Henriksson, H., 2022, In: Metabolism. 135, 14 p., 155268.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Exerkines in health, resilience and disease

    Chow, L. S., Gerszten, R. E., Taylor, J. M., Pedersen, B. K., van Praag, H., Trappe, S., Febbraio, M. A., Galis, Z. S., Gao, Y., Haus, J. M., Lanza, I. R., Lavie, C. J., Lee, C-H., Lucia, A., Moro, C., Pandey, A., Robbins, J. M., Stanford, K. I., Thackray, A. E., Villeda, S. & 5 others, Watt, M. J., Xia, A., Zierath, Juleen R, Goodpaster, B. H. & Snyder, M. P., 2022, In: Nature Reviews Endocrinology. 18, p. 273-289

    Research output: Contribution to journalReviewpeer-review

  25. Published

    Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

    Wang, Z., Emmerich, A., Pillon, N. J., Moore, T., Hemerich, D., Cornelis, M. C., Mazzaferro, E., Broos, S., Ahluwalia, T. S., Bartz, T. M., Bentley, A. R., Bielak, L. F., Chong, M., Chu, A. Y., Berry, D., Dorajoo, R., Dueker, N. D., Kasbohm, E., Feenstra, B., Feitosa, M. F. & 32 others, Gieger, C., Graff, M., Hall, L. M., Haller, T., Hartwig, F. P., Hillis, D. A., Huikari, V., Heard-Costa, N., Holzapfel, C., Jackson, A. U., Johansson, A., Jorgensen, A. M., Kaakinen, M. A., Karlsson, R., Kerr, K. F., Kim, B., Koolhaas, C. M., Kutalik, Z., Pacolet, A., Zhao, J., Balslev-Harder, M. N., Grarup, Niels, Linneberg, Allan René, Hansen, Torben, Melbye, Mads, Pedersen, Oluf Borbye, Pers, Tune H, Sørensen, Thorkild I.A., Zierath, Juleen R, Kilpeläinen, Tuomas O., Loos, Ruth & LifeLines Cohort Study, L. C. S., 2022, In: Nature Genetics. 54, p. 1332–1344 25 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    High-intensity interval training remodels the proteome and acetylome of human skeletal muscle

    Hostrup, Morten, Lemminger, A. K., Stocks, Ben Nicholas, Gonzalez-Franquesa, A., Larsen, Jeppe Kjærgaard, Prats Quesada, Júlia, Thomassen, Martin, Weinert, B. T., Bangsbo, Jens & Deshmukh, Atul Shahaji, 2022, In: eLife. 11, 37 p., 69802.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism

    Belda, E., Voland, L., Tremaroli, V., Falony, G., Adriouch, S., Assmann, K. E., Prifiti, E., Aron-Wisnewsky, J., Debedat, J., Le Roy, T., Nielsen, T., Amouyal, C., Andre, S., Andreelli, F., Blueher, M., Chakaroun, R., Chilloux, J., Coelho, L. P., Dao, M. C., Das, P. & 42 others, Fellahi, S., Forslund, S., Galleron, N., Hansen, T. H., Holmes, B., Ji, B., Pedersen, H. K., Phuong Le, Le Chatelier, E., Lewinter, C., Manneras-Holm, L., Marquet, F., Myridakis, A., Pelloux, V., Pons, N., Quinquis, B., Rouault, C., Roume, H., Salem, J., Sokolovska, N., Søndertoft, N. B., Touch, S., Vieira-Silva, S., Galan, P., Holst, Jens Juul, Gøtze, J. P., Køber, Lars Valeur, drb459, drb459, Hansen, Torben, Hercberg, S., Oppert, J., Nielsen, J., Letunic, I., Dumas, M., Stumvoll, M., Pedersen, Oluf Borbye, Bork, P., Ehrlich, S. D., Zucker, J., Baeckhed, F., Raes, J. & Clement, K., 2022, In: Gut. 71, 12, p. 2463-2480 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Insulin resistance rewires the metabolic gene program and glucose utilization in human white adipocytes

    Isidor, Marie Sophie, Dong, W., Servin-Uribe, R. I., Villarroel, J., Altıntaş, Ali, Ayala-Sumuano, J. T., Varela-Echavarría, A., Barrès, Romain, Stephanopoulos, G., Macotela, Y. & Emanuelli, Brice, 2022, In: International Journal of Obesity. 46, 3, p. 535-543

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Integrated Liver and Plasma Proteomics in Obese Mice Reveals Complex Metabolic Regulation

    Stocks, Ben Nicholas, Gonzalez-Franquesa, A., Borg, M. L., Björnholm, M., Niu, Lili, Zierath, Juleen R & Deshmukh, Atul Shahaji, 2022, In: Molecular and Cellular Proteomics. 21, 3, 19 p., 100207.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity

    Damgaard, Mads Vargas, Nielsen, Thomas Svava, Basse, A. L., Chubanava, Sabina, Trost, K., Moritz, Thomas, Dellinger, R. W., Larsen, Steen & Treebak, Jonas Thue, 2022, In: iScience. 25, 2, 21 p., 103863.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Palmitate impairs circadian transcriptomics in muscle cells through histone modification of enhancers

    Pillon, N. J., Puig, L. S., Altıntaş, Ali, Kamble, P. G., Casaní-Galdón, S., Gabriel, B. M., Barrès, Romain, Conesa, A., Chibalin, A. V., Näslund, E., Krook, A. & Zierath, Juleen R, 2022, In: Life Science Alliance. 6, 1, 14 p., e202201598.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Post-translational modifications: The signals at the intersection of exercise, glucose uptake and insulin sensitivity

    Stocks, Ben Nicholas & Zierath, Juleen R, 2022, In: Endocrine Reviews. 43, 4, p. 654-677 24 p.

    Research output: Contribution to journalReviewpeer-review

  33. Published

    Protocol to characterize mitochondrial supercomplexes from mouse tissues by combining BN-PAGE and MS-based proteomics

    Moreno Justicia, Roger, Gonzalez-Franquesa, A., Stocks, Ben Nicholas & Deshmukh, Atul Shahaji, 2022, In: STAR Protocols. 3, 1, 21 p., 101135.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published
  35. Published

    Reply to ‘Lactate as a major myokine and exerkine’

    Chow, L. S., Gerszten, R. E., Taylor, J. M., Pedersen, B. K., van Praag, H., Trappe, S., Febbraio, M. A., Galis, Z. S., Gao, Y., Haus, J. M., Lanza, I. R., Lavie, C. J., Lee, C. H., Lucia, A., Moro, C., Pandey, A., Robbins, J. M., Stanford, K. I., Thackray, A. E., Villeda, S. & 5 others, Watt, M. J., Xia, A., Zierath, Juleen R, Goodpaster, B. H. & Snyder, M., 2022, In: Nature Reviews Endocrinology. 18, 11, p. 713 1 p.

    Research output: Contribution to journalComment/debatepeer-review

  36. Published

    Transforming growth factor β1 impairs the transcriptomic response to contraction in myotubes from women with polycystic ovary syndrome

    McIlvenna, L. C., Altıntaş, Ali, Patten, R. K., McAinch, A. J., Rodgers, R. J., Stepto, N. K., Barrès, Romain & Moreno-Asso, A., 2022, In: The Journal of Physiology. 600, 14, p. 3313-3330

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Zeitgebers of skeletal muscle and implications for metabolic health

    Gabriel, B. M. & Zierath, Juleen R, 2022, In: Journal of Physiology. 600, 5, p. 1027-1036

    Research output: Contribution to journalJournal articlepeer-review

  38. 2021
  39. Published

    Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity

    Basse, A. L., Agerholm, M., Farup, J., Dalbram, E., Nielsen, J., Ørtenblad, N., Altıntaş, A., Ehrlich, A. M., Krag, T., Bruzzone, S., Dall, M., de Guia, R. M., Jensen, J. B., Møller, A. B., Karlsen, A., Kjær, M., Barrès, R., Vissing, J., Larsen, S., Jessen, N. & 1 others, Treebak, Jonas Thue, 2021, In: Molecular Metabolism. 53, 101271.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Ablation of DNA-methyltransferase 3A in skeletal muscle does not affect energy metabolism or exercise capacity

    Small, Lewin Barkla, Ingerslev, L. R., Manitta, Eleonora, Laker, R. C., Hansen, Ann Normann, Deeney, B., Carrie, A., Couvert, P. & Barrès, Romain, 2021, In: PLOS Genetics. 17, 1, 24 p., 1009325.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    COVID-19 editorial: mechanistic links and therapeutic challenges for metabolic diseases one year into the COVID-19 pandemic

    Tessier, C. M., Kokkinos, A., Mingrone, G., Koliaki, C., Zierath, Juleen R & Mantzoros, C. S., 2021, In: Metabolism. 119, 154769.

    Research output: Contribution to journalEditorial

  42. Published

    Cold-induction of afadin in brown fat supports its thermogenic capacity

    Lundh, M., Altıntaş, Ali, Tozzi, M., Fabre, O., Ma, Tao, Shamsi, F., Gerhart-Hines, Zach, Barrès, Romain, Tseng, Y. & Emanuelli, Brice, 2021, In: Scientific Reports. 11, 11 p., 9794.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle

    Rhein, P., Desjardins, E. M., Rong, P., Ahwazi, D., Bonhoure, N., Stolte, J., Santos, M. D., Ovens, A. J., Ehrlich, A. M., Sanchez Garcia, J. L., Ouyang, Q., Yabut, J. M., Kjolby, M., Membrez, M., Jessen, N., Oakhill, J. S., Treebak, J. T., Maire, P., Scott, J. W., Sanders, M. J. & 4 others, Descombes, P., Chen, S., Steinberg, G. R. & Sakamoto, Kei, 2021, In: Molecular Metabolism. 51, 18 p., 101228.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    Discovery of thymosin β4 as a human exerkine and growth factor

    Gonzalez-Franquesa, A., Stocks, Ben Nicholas, Borg, M. L., Kuefner, M., Kellezi, Emilie Dalbram, Nielsen, Thomas Svava, Agrawal, A., Pankratova, Stanislava, Chibalin, A. V., Karlsson, H. K. R., Gheibi, S., Björnholm, M., Jørgensen, Niklas Rye, Clemmensen, Christoffer, Treebak, Jonas Thue, Hostrup, Morten, Krook, A., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: American Journal of Physiology: Cell Physiology. 321, 5, p. C770-C778 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Disrupted circadian oscillations in type 2 diabetes are linked to altered rhythmic mitochondrial metabolism in skeletal muscle

    Gabriel, B. M., Altıntaş, Ali, Smith, J. A. B., Sardon-Puig, L., Zhang, X., Basse, A. L., Laker, R. C., Gao, H., Liu, Z., Dollet, L., Treebak, Jonas Thue, Zorzano, A., Huo, Z., Rydén, M., Lanner, J. T., Esser, K. A., Barrès, Romain, Pillon, N. J., Krook, A. & Zierath, Juleen R, 2021, In: Science Advances. 7, 43, 20 p., eabi9654.

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    Effects of lifestyle intervention in tissue‐specific lipidomic profile of formerly obese mice

    Dahdah, N., Gonzalez‐franquesa, A., Samino, S., Gama‐perez, P., Herrero, L., Perales, J. C., Yanes, O., Malagón, M. D. M. & Garcia‐roves, P. M., 2021, In: International Journal of Molecular Sciences. 22, 7, 18 p., 3694.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism

    Massart, J., Sjögren, R. J. O., Egan, B., Garde, C., Lindgren, M., Gu, W., Ferreira, D. M. S., Katayama, M., Ruas, J. L., Barrès, Romain, O'Gorman, D. J., Zierath, Juleen R & Krook, A., 2021, In: Nature Communications. 12, 1, 13 p., 5948.

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    Epigenetic rewiring of skeletal muscle enhancers after exercise training supports a role in the whole-body function and human health

    Williams, K., Carrasquilla, Germán D., Ingerslev, L. R., Hochreuter, Mette Yde, Hansson, Svenja, Pillon, N. J., Donkin, I., Versteyhe, S., Zierath, Juleen R, Kilpeläinen, Tuomas O. & Barrès, Romain, 2021, In: Molecular Metabolism. 53, 13 p., 101290.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Exercise during pregnancy mitigates negative effects of parental obesity on metabolic function in adult mouse offspring

    Laker, R. C. C., Altıntaş, Ali, Lillard, T. S., Zhang, M., Connelly, J. J., Sabik, O. L., Onengut, S., Rich, S. S., Farber, C. R., Barrès, Romain & Yan, Z., 2021, In: Journal of Applied Physiology. 130, 3, p. 605-616

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Insulin and 5-aminoimidazole-4-carboxamide ribonucleotide (Aicar) differentially regulate the skeletal muscle cell secretome

    Gonzalez-Franquesa, A., Peijs, Lone, Cervone, D. T., Koçana, C., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: Proteomes. 9, 3, 16 p., 37.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity

    Gonzalez-Franquesa, A., Stocks, Ben Nicholas, Chubanava, Sabina, Hattel, H. B., Moreno Justicia, Roger, Peijs, Lone, Treebak, Jonas Thue, Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: Cell Reports. 35, 8, 20 p., 109180.

    Research output: Contribution to journalJournal articlepeer-review

  52. Published

    Metabolic consequences of obesity and type 2 diabetes: Balancing genes and environment for personalized care

    Pillon, N. J., Loos, R. J. F., Marshall, S. M. & Zierath, Juleen R, 2021, In: Cell. 184, 6, p. 1530-1544 15 p.

    Research output: Contribution to journalReviewpeer-review

  53. Published

    Non-cell autonomous mechanisms control mitochondrial gene dysregulation in polycystic ovary syndrome

    Moreno-Asso, A., Altıntaş, Ali, McIlvenna, L. C., Patten, R. K., Botella, J., McAinch, A. J., Rodgers, R. J., Barrès, Romain & Stepto, N. K., 2021, In: Journal of Molecular Endocrinology. 68, 1, p. 63-76

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    Perinatal exposure to nicotine alters spermatozoal DNA methylation near genes controlling nicotine action

    Altıntaş, Ali, Liu, J., Fabre, O., Chuang, T., Wang, Y., Sakurai, R., Chehabi, G. N., Barrès, Romain & Rehan, V. K., 2021, In: F A S E B Journal. 35, 7, e21702.

    Research output: Contribution to journalJournal articlepeer-review

  55. Published

    Quantitative phosphoproteomic analysis of IRS1 in skeletal muscle from men with normal glucose tolerance or type 2 diabetes: A case-control study

    Karlsson, H. K. R., Kasahara, A., Ikeda, M., Chibalin, A. V., Harada, J., Rydén, M., Krook, A., Kato, M., Kubota, K. & Zierath, Juleen R, 2021, In: Metabolism. 118, 7 p., 154726.

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    The Comparative Methylome and Transcriptome After Change of Direction Compared to Straight Line Running Exercise in Human Skeletal Muscle

    Maasar, M. F., Turner, D. C., Gorski, P. P., Seaborne, R. A., Strauss, J. A., Shepherd, S. O., Cocks, M., Pillon, N. J., Zierath, Juleen R, Hulton, A. T., Drust, B. & Sharples, A. P., 2021, In: Frontiers in Physiology. 12, 17 p., 619447.

    Research output: Contribution to journalJournal articlepeer-review

  57. Published

    The role of the molecular circadian clock in human energy homeostasis

    Dollet, L., Pendergrast, L. A. & Zierath, Juleen R, 2021, In: Current Opinion in Lipidology. 32, 1, p. 16-23 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  58. Published

    White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment

    Rabiee, A., Plucinska, Kaja, Isidor, Marie Sophie, Brown, E. L., Tozzi, M., Sidoli, S., Petersen, P. S. S., Agueda Oyarzabal, Marina, Torsetnes, S. B., Chehabi, G. N., Lundh, M., Altıntaş, Ali, Barrès, Romain, Jensen, O. N., Gerhart-Hines, Zach & Emanuelli, Brice, 2021, In: Molecular Metabolism. 44, 17 p., 101137.

    Research output: Contribution to journalJournal articlepeer-review

  59. 2020
  60. Published

    A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes

    Batista, T. M., Jayavelu, A. K., Albrechtsen, Nicolai Jacob Wewer, Iovino, S., Lebastchi, J., Pan, H., Dreyfuss, J. M., Krook, A., Zierath, Juleen R, Mann, Matthias & Kahn, C. R., 2020, In: Cell Metabolism. 32, 5, p. 844-859.e5

    Research output: Contribution to journalJournal articlepeer-review

  61. Published

    Chrono-nutrition for the prevention and treatment of obesity and type 2 diabetes: from mice to men

    Hawley, J. A., Sassone-Corsi, P. & Zierath, Juleen R, 2020, In: Diabetologia. 63, 11, p. 2253-2259 7 p.

    Research output: Contribution to journalReviewpeer-review

  62. Published

    Comparative profiling of skeletal muscle models reveals heterogeneity of transcriptome and metabolism

    Abdelmoez, A. M., Puig, L. S., Smith, J. A. B., Gabriel, B. M., Savikj, M., Dollet, L., Chibalin, A. V., Krook, A., Zierath, Juleen R & Pillon, N. J., 2020, In: American Journal of Physiology: Cell Physiology. 318, 3, p. C615-C626 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  63. Published

    Contraction influences Per2 gene expression in skeletal muscle through a calcium-dependent pathway

    Small, Lewin Barkla, Altıntaş, Ali, Laker, R. C., Ehrlich, Amy M, Pattamaprapanont, P., Villarroel, J., Pillon, N. J., Zierath, Juleen R & Barrès, Romain, 2020, In: The Journal of Physiology. 598, 24, p. 5739-5752

    Research output: Contribution to journalJournal articlepeer-review

  64. Published

    Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise

    Brandão, B. B., Madsen, S., Rabiee, A., Oliverio, M., Ruiz, G. P., Ferrucci, D. L., Branquinho, J. L., Razolli, D., Pinto, S., Nielsen, T. S., Festuccia, W. T., Martins, A. S., Guerra, B. A., Knittel, T. L., Søgaard, D., Larsen, S., Helge, J. W., Brandauer, J., Velloso, L. A., Emanuelli, B. & 6 others, Kornfeld, J., Kahn, C. R., Vienberg, S. G., Zierath, Juleen R, Treebak, Jonas Thue & Mori, M. A., 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 38, p. 23932-23941

    Research output: Contribution to journalJournal articlepeer-review

  65. Published

    Influence of obesity, weight loss, and free fatty acids on skeletal muscle clock gene expression

    Puig, L. S., Pillon, N. J., Naslund, E., Krook, A. & Zierath, Juleen R, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 1, p. E1-E10 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  66. Published

    Insulin-induced serine 22 phosphorylation of retinoid X receptor alpha is dispensable for adipogenesis in brown adipocytes

    Ardenkjær-Larsen, J., Rupar, K., Snieckute, Goda, Petersen, P. S. S., Villarroel, J., Lundh, M., Barrès, Romain, Rabiee, A. & Emanuelli, Brice, 2020, In: Adipocyte (Philadelphia). 9, 1, p. 142-152 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  67. Published

    Next Generation Diabetes Scientists Shape Global Research Culture: A reflective proposal from postdoctoral researchers in diabetes research

    Gonzalez-Franquesa, A., Carrasquilla Lopez, G. D., Mamidi, A., Ghiasi, S. M., Juel, H. B., Falk, S., Isidor, M. S., Gillberg, L. M. E., Huang, L. O., Quist, J. S., Knudsen, J. R., Quaranta, R., Tozzi, M., Mikkelsen, R. B., Dall, M., Drag, M. H., Small, L. B., Altıntaş, A., Osborne, B., Modvig, I. M. & 11 others, Husted, Anna Sofie, Brown, E. L., Bak, Emilie Glad, Bastos Peluso, A. A., Finger, Fabian Michael, Grunddal, Kaare Villum, Rupar, K., Henningsen, J. B., Pedersen, M. H., Plucinska, Kaja & Attendees of the Danish Diabetes Academy Winter School 2019, A. O. T. D. D. A. W. S. 2., 2020, In: Acta Physiologica. 229, 2, 5 p., e13455.

    Research output: Contribution to journalComment/debate

  68. Published

    Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin resistant men

    Dollerup, O. L., Chubanava, Sabina, Agerholm, M., Søndergård, S. D., Altıntaş, Ali, Møller, A. B., Høyer, K. F., Ringgaard, S., Stødkilde-Jørgensen, H., Lavery, G. G., Barrès, Romain, Larsen, Steen, Prats Gavalda, Clara, Jessen, N. & Treebak, Jonas Thue, 2020, In: Journal of Physiology. 598, 4, p. 731-754

    Research output: Contribution to journalJournal articlepeer-review

  69. Published

    Pyruvate kinase M2 represses thermogenic gene expression in brown adipocytes

    Isidor, Marie Sophie, Winther, Sally, Markussen, L. K., Basse, A. L., Quistorff, B., Nedergaard, J., Emanuelli, Brice & Hansen, Jacob B., 2020, In: FEBS Letters. 594, 7, p. 1218-1225

    Research output: Contribution to journalJournal articlepeer-review

  70. Published

    Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism

    Williams, K., Ingerslev, L. R., Bork-Jensen, J., Wohlwend, M., Hansen, Ann Normann, Small, Lewin Barkla, Ribel-Madsen, R., Astrup, A., Pedersen, Oluf Borbye, Auwerx, J., Workman, C. T., Grarup, Niels, Hansen, Torben & Barrès, Romain, 2020, In: Nature Communications. 11, 16 p., 2695.

    Research output: Contribution to journalJournal articlepeer-review

  71. Published

    Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression: [Author Correction]

    Lundell, L. S., Parr, E. B., Devlin, B. L., Ingerslev, L. R., Altıntaş, Ali, Sato, S., Sassone-Corsi, P., Barrès, Romain, Zierath, Juleen R & Hawley, J. A., 2020, In: Nature Communications. 11, 1, 11 p., 4643.

    Research output: Contribution to journalJournal articlepeer-review

  72. Published

    Train like an athlete: applying exercise interventions to manage type 2 diabetes

    Savikj, M. & Zierath, Juleen R, 2020, In: Diabetologia. 63, 8, p. 1491-1499

    Research output: Contribution to journalReviewpeer-review

  73. Published

    Transcriptomic and epigenomics atlas of myotubes reveals insight into the circadian control of metabolism and development

    Altıntaş, Ali, Laker, R. C., Garde, C., Barrès, Romain & Zierath, Juleen R, 2020, In: Epigenomics. 12, 8, p. 701-713

    Research output: Contribution to journalJournal articlepeer-review

  74. Published

    Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity

    Pillon, N. J., Gabriel, B. M., Dollet, L., Smith, J. A. B., Puig, L. S., Botella, J., Bishop, D. J., Krook, A. & Zierath, Juleen R, 2020, In: Nature Communications. 11, 1, 15 p., 470.

    Research output: Contribution to journalJournal articlepeer-review

  75. 2019
  76. Published

    Calorie restriction prevents diet-induced insulin resistance independently of PGC-1-driven mitochondrial biogenesis in white adipose tissue

    Pardo, R., Vila, M., Cervela, L., de Marco, M., Gama-Perez, P., Gonzalez-Franquesa, A., Statuto, L., Vilallonga, R., Simo, R., Garcia-Roves, P. M. & Villena, J. A., 2019, In: FASEB Journal. 33, 2, p. 2343-2358

    Research output: Contribution to journalJournal articlepeer-review

  77. Published

    Circadian rhythms and exercise - re-setting the clock in metabolic disease

    Gabriel, B. M. & Zierath, Juleen R, 2019, In: Nature Reviews Endocrinology. 15, 4, p. 197-206

    Research output: Contribution to journalReviewpeer-review

  78. Published

    Environmental factors influence the epigenetic signature of newborns from mothers with gestational diabetes

    Andersen, E., Altıntaş, Ali, Andersson-Hall, U., Holmäng, A. & Barrès, Romain, 2019, In: Epigenomics. 11, 8, p. 861-873 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  79. Published

    Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function

    Hiam, D., Simar, D., Laker, R., Altıntaş, Ali, Gibson-Helm, M., Fletcher, E., Moreno-Asso, A., Trewin, A. J., Barrès, Romain & Stepto, N. K., 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 12, p. 6155-6170

    Research output: Contribution to journalJournal articlepeer-review

  80. Published

    Heterogeneity in the perirenal region of humans suggests presence of dormant brown adipose tissue that contains brown fat precursor cells

    Jespersen, N. Z., Feizi, A., Andersen, E. S., Heywood, S., Hattel, H. B., Daugaard, S., Peijs, Lone, Bagi, P., Feldt-Rasmussen, Bo, Schultz, H. S., Hansen, N. S., Krogh-Madsen, Rikke, Pedersen, Bente Klarlund, Petrovic, N., Nielsen, S. & Schéele, Camilla Charlotte Nielsen, 2019, In: Molecular Metabolism. 24, p. 30-43 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  81. Published

    Identification of two microRNA nodes as potential cooperative modulators of liver metabolism

    Hochreuter, Mette Yde, Altıntaş, Ali, Garde, C., Emanuelli, Brice, Kahn, C. R., Zierath, Juleen R, Vienberg, S. & Barrès, Romain, 2019, In: Hepatology Research. 49, 12, p. 1451-1465

    Research output: Contribution to journalJournal articlepeer-review

  82. Published

    Interplay between diet, exercise and the molecular circadian clock in orchestrating metabolic adaptations of adipose tissue

    Dollet, L. & Zierath, Juleen R, 2019, In: Journal of Physiology. 597, 6, p. 1439-1450

    Research output: Contribution to journalReviewpeer-review

  83. Published

    Mechanisms preserving insulin action during high dietary fat intake

    Lundsgaard, Anne-Marie, Holm, J. B., Sjøberg, K. A., Bojsen-Møller, K. N., Myrmel, L. S., Fjære, E., Jensen, Benjamin Anderschou Holbech, Nicolaisen, T. S., Hingst, J. R., Hansen, S. L., Doll, S., Geyer, P. E., Deshmukh, Atul Shahaji, Holst, Jens Juul, Madsen, L., Kristiansen, Karsten, Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2019, In: Cell Metabolism. 29, 1, p. 50-63, e1-e4 19 p.

    Research output: Contribution to journalJournal articlepeer-review

  84. Published

    Protein aggregation capture on microparticles enables multi-purpose proteomics sample preparation

    Batth, Tanveer Singh, Tollenaere, M. A. X., Rüther, P. L., Gonzalez-Franquesa, A., Prabhakar, B. S., Bekker-Jensen, Simon Holst, Deshmukh, Atul Shahaji & Olsen, Jesper Velgaard, 2019, In: Molecular and Cellular Proteomics. 18, 5, p. 1027-1035

    Research output: Contribution to journalJournal articlepeer-review

  85. Published

    Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

    Deshmukh, A. S., Peijs, L., Beaudry, J. L., Jespersen, N. Z., Nielsen, C. H., Ma, T., Brunner, A. D., Larsen, T. J., Bayarri-Olmos, R., Prabhakar, B. S., Helgstrand, C., Severinsen, M. C. K., Holst, B., Kjaer, A., Tang-Christensen, M., Sanfridson, A., Garred, P., Privé, G. G., Pedersen, B. K., Gerhart-Hines, Z. & 4 others, Nielsen, S., Drucker, D. J., Mann, Matthias & Schéele, Camilla Charlotte Nielsen, 2019, In: Cell Metabolism. 30, 5, p. 963-975.e7 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  86. Published

    Regulation of glucose uptake and inflammation markers by FOXO1 and FOXO3 in skeletal muscle

    Lundell, L. S., Massart, J., Altıntaş, Ali, Krook, A. & Zierath, Juleen R, 2019, In: Molecular Metabolism. 20, p. 79-88 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  87. Published

    Role of Diacylglycerol Kinases in Glucose and Energy Homeostasis

    Massart, J. & Zierath, Juleen R, 2019, In: Trends in Endocrinology and Metabolism. 30, 9, p. 603-617

    Research output: Contribution to journalReviewpeer-review

  88. Published

    Time of Exercise Specifies the Impact on Muscle Metabolic Pathways and Systemic Energy Homeostasis

    Sato, S., Basse, A. L., Schönke, M., Chen, S., Samad, M., Altıntaş, Ali, Laker, R. C., Kellezi, Emilie Dalbram, Barrès, Romain, Baldi, P., Treebak, Jonas Thue, Zierath, Juleen R & Sassone-Corsi, P., 2019, In: Cell Metabolism. 30, 1, p. 92-110.e4 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  89. Published

    Voluntary wheel running in the late dark phase ameliorates diet-induced obesity in mice without altering insulin action

    Kellezi, Emilie Dalbram, Basse, A. L., Zierath, Juleen R & Treebak, Jonas Thue, 2019, In: Journal of Applied Physiology. 126, 4, p. 993-1005 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  90. 2018
  91. Published

    Squeezing Flux Out of Fat

    Gonzalez-Franquesa, A. & Patti, M., 2018, In: Trends in Endocrinology and Metabolism. 29, 4, p. 201-202

    Research output: Contribution to journalJournal articlepeer-review

  92. 2015
  93. Published

    Quantification of oxidative stress phenotypes based on high-throughput growth profiling of protein kinase and phosphatase knockouts.

    Altıntaş, Ali, 11 Nov 2015, In: FEMS Yeast Research.

    Research output: Contribution to journalJournal articlepeer-review

  94. Published

    Diabetes mellitus and metabolic syndrome

    Ortega, E., Martín-Cordero, L., Garcia-Roves, P. M., Chicco, A. J., Gonzalez-Franquesa, A. & Marado, D., 1 Jan 2015, Biomarkers of Cardiometabolic Risk, Inflammation and Disease. Springer, p. 55-79 25 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  95. 2014
  96. Published

    Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice

    Zachariah Tom, R., Garcia-Roves, P. M., Sjögren, R. J. O., Jiang, L. Q., Holmström, M. H., Deshmukh, Atul Shahaji, Vieira, E., Chibalin, A. V., Björnholm, M. & Zierath, Juleen R, May 2014, In: Diabetes. 63, 5, p. 1560-71 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  97. 2013
  98. Published

    Contrasting metabolic effects of medium-versus long-chain fatty acids in skeletal muscle

    Montgomery, M. K., Osborne, Brenna, Brown, S. H. J., Small, Lewin Barkla, Mitchell, T. W., Cooney, G. J. & Turner, N., Dec 2013, In: Journal of Lipid Research. 54, 12, p. 3322-3333 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  99. 2008
  100. Published

    Role of AMPK in IL-6 release from isolated mouse skeletal muscle

    Glund, S., Treebak, Jonas Thue, Long, Y. C., Barrès, Romain, Viollet, B., Wojtaszewski, Jørgen F P & Zierath, Juleen R, 2008, In: Diabetologia.

    Research output: Contribution to journalJournal articlepeer-review