Chrono-nutrition for the prevention and treatment of obesity and type 2 diabetes: from mice to men

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Chrono-nutrition for the prevention and treatment of obesity and type 2 diabetes : from mice to men. / Hawley, John A.; Sassone-Corsi, Paolo; Zierath, Juleen R.

In: Diabetologia, Vol. 63, No. 11, 2020, p. 2253-2259.

Research output: Contribution to journalReviewpeer-review

Harvard

Hawley, JA, Sassone-Corsi, P & Zierath, JR 2020, 'Chrono-nutrition for the prevention and treatment of obesity and type 2 diabetes: from mice to men', Diabetologia, vol. 63, no. 11, pp. 2253-2259. https://doi.org/10.1007/s00125-020-05238-w

APA

Hawley, J. A., Sassone-Corsi, P., & Zierath, J. R. (2020). Chrono-nutrition for the prevention and treatment of obesity and type 2 diabetes: from mice to men. Diabetologia, 63(11), 2253-2259. https://doi.org/10.1007/s00125-020-05238-w

Vancouver

Hawley JA, Sassone-Corsi P, Zierath JR. Chrono-nutrition for the prevention and treatment of obesity and type 2 diabetes: from mice to men. Diabetologia. 2020;63(11):2253-2259. https://doi.org/10.1007/s00125-020-05238-w

Author

Hawley, John A. ; Sassone-Corsi, Paolo ; Zierath, Juleen R. / Chrono-nutrition for the prevention and treatment of obesity and type 2 diabetes : from mice to men. In: Diabetologia. 2020 ; Vol. 63, No. 11. pp. 2253-2259.

Bibtex

@article{7a38a44b19fe4478a7a7b494a138c1b2,
title = "Chrono-nutrition for the prevention and treatment of obesity and type 2 diabetes: from mice to men",
abstract = "The proliferation in the rate of diagnosis of obesity and type 2 diabetes mellitus continues unabated, with current recommendations for primary lifestyle changes (i.e. modification to dietary patterns) having a limited impact in reducing the incidence of these metabolic diseases. Part of the reason for the failure to alter nutritional practices is that current dietary recommendations may be unrealistic for the majority of adults. Indeed, round-the-clock access to energy-dense, nutrient-poor food makes long-term changes to dietary habits challenging. Hence, there is urgent need for innovations in the delivery of evidence-based diet interventions to rescue some of the deleterious effects on circadian biology induced by our modern-day lifestyle. With the growing appreciation that the duration over which food is consumed during a day has profound effects on numerous physiological and metabolic processes, we discuss dietary protocols that modify thetimingof food intake to deliberately alter the feeding-fasting cycle. Such chrono-nutrition functions to optimise metabolism by timing nutrient intake to the acrophases of metabolic rhythms to improve whole-body insulin sensitivity and glycaemic control, and thereby positively impact metabolic health.",
keywords = "Chronic energy restriction, Circadian disruption, Circadian rhythm, Diet, Food, Glycaemia, Intermittent fasting, Metabolic disease, Obesity, Review, Time-restricted eating, GLUCOSE-METABOLISM, CIRCADIAN DISRUPTION, PRACTICE GUIDELINE, TIME, DISEASE, ADULTS, FAT, RECOMMENDATIONS, INTERVENTION, ASSOCIATION",
author = "Hawley, {John A.} and Paolo Sassone-Corsi and Zierath, {Juleen R.}",
year = "2020",
doi = "10.1007/s00125-020-05238-w",
language = "English",
volume = "63",
pages = "2253--2259",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer",
number = "11",

}

RIS

TY - JOUR

T1 - Chrono-nutrition for the prevention and treatment of obesity and type 2 diabetes

T2 - from mice to men

AU - Hawley, John A.

AU - Sassone-Corsi, Paolo

AU - Zierath, Juleen R.

PY - 2020

Y1 - 2020

N2 - The proliferation in the rate of diagnosis of obesity and type 2 diabetes mellitus continues unabated, with current recommendations for primary lifestyle changes (i.e. modification to dietary patterns) having a limited impact in reducing the incidence of these metabolic diseases. Part of the reason for the failure to alter nutritional practices is that current dietary recommendations may be unrealistic for the majority of adults. Indeed, round-the-clock access to energy-dense, nutrient-poor food makes long-term changes to dietary habits challenging. Hence, there is urgent need for innovations in the delivery of evidence-based diet interventions to rescue some of the deleterious effects on circadian biology induced by our modern-day lifestyle. With the growing appreciation that the duration over which food is consumed during a day has profound effects on numerous physiological and metabolic processes, we discuss dietary protocols that modify thetimingof food intake to deliberately alter the feeding-fasting cycle. Such chrono-nutrition functions to optimise metabolism by timing nutrient intake to the acrophases of metabolic rhythms to improve whole-body insulin sensitivity and glycaemic control, and thereby positively impact metabolic health.

AB - The proliferation in the rate of diagnosis of obesity and type 2 diabetes mellitus continues unabated, with current recommendations for primary lifestyle changes (i.e. modification to dietary patterns) having a limited impact in reducing the incidence of these metabolic diseases. Part of the reason for the failure to alter nutritional practices is that current dietary recommendations may be unrealistic for the majority of adults. Indeed, round-the-clock access to energy-dense, nutrient-poor food makes long-term changes to dietary habits challenging. Hence, there is urgent need for innovations in the delivery of evidence-based diet interventions to rescue some of the deleterious effects on circadian biology induced by our modern-day lifestyle. With the growing appreciation that the duration over which food is consumed during a day has profound effects on numerous physiological and metabolic processes, we discuss dietary protocols that modify thetimingof food intake to deliberately alter the feeding-fasting cycle. Such chrono-nutrition functions to optimise metabolism by timing nutrient intake to the acrophases of metabolic rhythms to improve whole-body insulin sensitivity and glycaemic control, and thereby positively impact metabolic health.

KW - Chronic energy restriction

KW - Circadian disruption

KW - Circadian rhythm

KW - Diet

KW - Food

KW - Glycaemia

KW - Intermittent fasting

KW - Metabolic disease

KW - Obesity

KW - Review

KW - Time-restricted eating

KW - GLUCOSE-METABOLISM

KW - CIRCADIAN DISRUPTION

KW - PRACTICE GUIDELINE

KW - TIME

KW - DISEASE

KW - ADULTS

KW - FAT

KW - RECOMMENDATIONS

KW - INTERVENTION

KW - ASSOCIATION

U2 - 10.1007/s00125-020-05238-w

DO - 10.1007/s00125-020-05238-w

M3 - Review

C2 - 32761356

VL - 63

SP - 2253

EP - 2259

JO - Diabetologia

JF - Diabetologia

SN - 0012-186X

IS - 11

ER -

ID: 249860767