Regulation of Metabolism by Microbial Metabolites in the Bäckhed Group

The main goal of the group is to understand the repertoire of microbially produced metabolites that modulates insulin signaling and to identify host receptors and signaling pathways with the greater aim of identifying therapeutic targets to treat cardiometabolic diseases.

Close-up photo of the hands of a researcher working in the lab

 

 

 

 

 

 

 

 

The microbial community has an immense capacity to affect host biology and is fundamental to many processes, including the development of our immune system, processing of otherwise indigestible dietary polysaccharides, and vitamin and hormone production. The gut microbiome encodes perhaps 1000-fold more genes than the human genome and provides us with numerous complementary functions and activities.

The overall aim of the Bäckhed Group is to clarify the role of bacteria associated with the human body in the development of metabolic diseases, with particular emphasis on diabetes. A main focus is to identify microbially produced metabolites that contributes to insulin resistance and their host receptors as well as identify how such metabolites affect enteroendocrine cell biology.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Group Leader Fredrik Bäckhed

Group Leader

Fredrik Bäckhed
Professor

Phone +45 3533 7033
gert.backhed@sund.ku.dk

Group members

Name Title Phone E-mail
Arora, Tulika Assistant Professor +4535335383 E-mail
Bäckhed, Gert Fredrik Professor +4535337033 E-mail
Johansen, Marianne Gregers Laboratory Technician. +4535334413 E-mail
Mikkelsen, Randi Bonke Postdoc +4535334898 E-mail
Rosenberg, Carina Onuczak Animal Keeper +4535332738 E-mail