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A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening
van den Berg, R., Kooijman, S., Noordam, R., Ramkisoensing, A., Abreu-Vieira, G., Tambyrajah, L. L., Dijk, W., Ruppert, P., Mol, I. M., Kramar, B., Caputo, R., Puig, L. S., de Ruiter, E. M., Kroon, J., Hoekstra, M., van der Sluis, R. J., Meijer, O. C., Willems van Dijk, K., van Kerkhof, L. W. M., Christodoulides, C. & 8 others, , 2018, In: Cell Reports. 22, 13, p. 3521-3533 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A metabolic prosurvival role for PML in breast cancer
Carracedo, A., Weiss, D., Leliaert, A. K., Bhasin, M., De Boer, V. C. J., Laurent, G., Adams, A. C., Sundvall, M., Song, S. J., Ito, K., Finley, L. S., Egia, A., Libermann, T., Gerhart-Hines, Zach, Puigserver, P., Haigis, M. C., Maratos-Flier, E., Richardson, A. L., Schafer, Z. T. & Pandolfi, P. P., 4 Sep 2012, In: Journal of Clinical Investigation. 122, 9, p. 3088-3100 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ADRA1A–Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP
Rahbani, J. F., Scholtes, C., Lagarde, D. M., Hussain, M. F., Roesler, A., Dykstra, C. B., Bunk, J., Samborska, B., O’Brien, S. L., Tripp, E., Pacis, A., Angueira, A. R., Johansen, O. S., Cinkornpumin, J., Hossain, I., Lynes, M. D., Zhang, Y., White, A. P., Pastor, W. A., Chondronikola, M. & 12 others, , 2022, In: Nature Metabolism. 4, 11, p. 1459-1473Research output: Contribution to journal › Letter › Research › peer-review
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AMPK regulates energy expenditure by modulating NAD + metabolism and SIRT1 activity
Cantó, C., Gerhart-Hines, Zach, Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P. & Auwerx, J., 23 Apr 2009, In: Nature. 458, 7241, p. 1056-1060 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting- and ghrelin-mediated food intake
de Guia, R. M., Hassing, Anna Skab, Ma, Tao, Plucinska, Kaja, Holst, Birgitte, Gerhart-Hines, Zach, Emanuelli, Brice & Treebak, Jonas Thue, 2021, In: F A S E B Journal. 35, 5, e21450.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute Deletion of the Glucocorticoid Receptor in Hepatocytes Disrupts Postprandial Lipid Metabolism in Male Mice
Correia, C. M., Præstholm, S. M., Havelund, J. F., Boel, Felix, Siersbæk, M. S., Ebbesen, M. F., Gerhart-Hines, Zach, Heeren, J., Brewer, J., Larsen, Steen, Blagoev, B., Færgeman, N. J. & Grøntved, L., 2023, In: Endocrinology. 164, 10, p. 1-17 164.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute and long-term effects of psilocybin on energy balance and feeding behavior in mice
Fadahunsi, N., Lund, Jens, Breum, Alberte Wollesen, Mathiesen, C. V., Larsen, I. B., Knudsen, Gitte Moos, Klein, A. B. & Clemmensen, Christoffer, 2022, In: Translational Psychiatry. 12, 12 p., 330.Research output: Contribution to journal › Journal article › Research › peer-review
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Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue
Lundh, M., Petersen, P. S., Isidor, Marie Sophie, Kazoka-Sørensen, D. N., Plucinska, Kaja, Shamsi, F., Ørskov, Cathrine, Tozzi, M., Brown, E. L., Andersen, E., Ma, Tao, Müller, U. A., Barrès, Romain, Kristiansen, V. B., Gerhart-Hines, Zach, Tseng, Y. & Emanuelli, Brice, 2019, In: EMBO Reports. 20, 8, e48216.Research output: Contribution to journal › Journal article › Research › peer-review
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Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men
Soberg, S., Löfgren, J., Philipsen, F. E., Jensen, M., Hansen, Adam Espe, Ahrens, E., Nystrup, K. B., Nielsen, R. D., Solling, C., Wedell-Neergaard, A., Berntsen, M., Loft, A., Kjær, Andreas, Gerhart-Hines, Zach, Johannesen, H. H., Pedersen, Bente Klarlund, Karstoft, Kristian & Schéele, Camilla Charlotte Nielsen, 2021, In: Cell Reports Medicine. 2, 10, 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
Schafer, Z. T., Grassian, A. R., Song, L., Jiang, Z., Gerhart-Hines, Zach, Irie, H. Y., Gao, S., Puigserver, P. & Brugge, J. S., 3 Sep 2009, In: Nature. 461, 7260, p. 109-113 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Atlas of exercise-induced brain activation in mice
Skovbjerg, G., Fritzen, Andreas Mæchel, Svendsen, C. S. A., Perens, J., Skytte, J. L., Lund, Camilla, Lund, Jens, Madsen, M. R., Roostalu, U., Hecksher-Sørensen, J. & Clemmensen, Christoffer, 2024, In: Molecular Metabolism. 82, 14 p., 101907.Research output: Contribution to journal › Journal article › Research › peer-review
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Autocrine negative feed-back regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT
Husted, Anna Sofie, Ekberg, J. H., Tripp, E., Nissen, T. A. D., Meijnikman, S., O'Brien, S. L., Ulven, Trond, Acherman, Y., Bruin, S. C., Nieuwdorp, M., Gerhart-Hines, Zach, Calebiro, D., Dragsted, Lars Ove & Schwartz, Thue W., 2020, In: Molecular Metabolism. 42, 10 p., 101103.Research output: Contribution to journal › Journal article › Research › peer-review
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Brown fat: the biological furnace that could burn away obesity
Lund, Jens, Peics, J. & Gerhart-Hines, Zach, 2018, In: Biozoom. 20, 3, p. 4-6 3 p.Research output: Contribution to journal › Journal article › Research
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Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
Sustarsic, E. G., Ma, T., Lynes, M. D., Larsen, M., Karavaeva, I., Havelund, J. F., Nielsen, C. H., Jedrychowski, M. P., Moreno-Torres, M., Lundh, M., Plucinska, K., Jespersen, N. Z., Grevengoed, T. J., Kramar, B., Peics, J., Hansen, J. B., Shamsi, F., Forss, I., Neess, D., Keipert, S. & 24 others, , 2018, In: Cell Metabolism. 28, 1, p. 159-174.e11Research output: Contribution to journal › Journal article › Research › peer-review
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Chasing the hunger-suppressive signals of human exercise
Brunetta, H. S. & Lund, Jens, 2023, In: Journal of Physiology. 601, 16, p. 3441-3442 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo
Fang, B., Everett, L. J., Jager, J., Briggs, E., Armour, S. M., Feng, D., Roy, A., Gerhart-Hines, Zach, Sun, Z. & Lazar, M. A., 20 Nov 2014, In: Cell. 159, 5, p. 1140-1152 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cold-Activated Lipid Dynamics in Adipose Tissue Highlights a Role for Cardiolipin in Thermogenic Metabolism
Lynes, M. D., Shamsi, F., Sustarsic, E. G., Leiria, L. O., Wang, C. H., Su, S. C., Huang, T. L., Gao, Fei, Narain, N. R., Chen, E. Y., Cypess, A. M., Schulz, T. J., Gerhart-Hines, Zach, Kiebish, M. A. & Tseng, Y. H., 2018, In: Cell Reports. 24, 3, p. 781-790 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cold-induction of afadin in brown fat supports its thermogenic capacity
Lundh, M., Altıntaş, Ali, Tozzi, M., Fabre, O., Ma, Tao, Shamsi, F., Gerhart-Hines, Zach, Barrès, Romain, Tseng, Y. & Emanuelli, Brice, 2021, In: Scientific Reports. 11, 11 p., 9794.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative profiling of skeletal muscle models reveals heterogeneity of transcriptome and metabolism
Abdelmoez, A. M., Puig, L. S., Smith, J. A. B., Gabriel, B. M., Savikj, M., Dollet, L., Chibalin, A. V., Krook, A., Zierath, Juleen R & Pillon, N. J., 2020, In: American Journal of Physiology: Cell Physiology. 318, 3, p. C615-C626 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells
Suchankova, G., Nelson, L. E., Gerhart-Hines, Zach, Kelly, M., Gauthier, M. S., Saha, A. K., Ido, Y., Puigserver, P. & Ruderman, N. B., 23 Jan 2009, In: Biochemical and Biophysical Research Communications. 378, 4, p. 836-841 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells
Møller, S. H., Mellergaard, M., Madsen, M., Bermejo, A. V., Jepsen, Stine Dam, Hansen, M. H., Høgh, R. I., Aldana, Blanca, Desler, Claus, Rasmussen, Lene Juel, Sustarsic, E. G., Gerhart-Hines, Zach, Daskalaki, E., Wheelock, C. E., Hiron, T. K., Lin, D., O'Callaghan, C. A., Wandall, Hans H., Andresen, Lars & Skov, Søren, 2020, In: Frontiers in Immunology. 11, 22 p., 1968.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice
Kanta, Josephine Maria, Deisen, L., Johann, K., Holm, Stephanie Kjærulff, Lundsgaard, Anne-Marie, Lund, Jens, Jähnert, M., Schürmann, A., Clemmensen, Christoffer, Kiens, Bente, Fritzen, Andreas Mæchel & Kleinert, Maximilian, 2023, In: Molecular Metabolism. 74, 10 p., 101760.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Editorial overview: Fat tissue in focus: Assembled deeply insightful perspectives on state-of-the-art explorations
Gerhart-Hines, Zach & Loos, Ruth, 2023, In: Current Opinion in Genetics and Development. 83, 102117.Research output: Contribution to journal › Editorial › Research
- Published
Effect of Simvastatin Treatment on Mitochondrial Function and Inflammatory Status of Human White Adipose Tissue
Bager Christensen, I., Blom, Ida, Dohlmann, T. L., Finger, Fabian Michael, Helge, Jørn Wulff, Gerhart-Hines, Zach, Dela, Flemming & Larsen, Steen, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 10, p. e916-e922 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epidermal Acyl-CoA-binding protein is indispensable for systemic energy homeostasis
Neess, D., Kruse, V., Marcher, A. B., Wæde, M. R., Vistisen, J., Møller, P. M., Petersen, R., Brewer, J. R., Ma, Tao, Colleluori, G., Severi, I., Cinti, S., Gerhart-Hines, Zach, Mandrup, S. & Færgeman, N. J., 2021, In: Molecular Metabolism. 44, 11 p., 101144.Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
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A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening
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NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity
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Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
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Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M
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MCT1 helps brown fat suck up succinate
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