- 2016
- Published
Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits
CHARGE Consortium Hematology Working Group, C. C. H. W. G., Aug 2016, In: Nature Genetics. 48, 8, p. 867-876 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
Ried, J. S., Jeff M, J., Chu, A. Y., Bragg-Gresham, J. L., van Dongen, J., Huffman, J. E., Ahluwalia, T. V. S., Cadby, G., Eklund, N., Eriksson, J., Esko, T., Feitosa, M. F., Goel, A., Gorski, M., Hayward, C., Heard-Costa, N. L., Jackson, A. U., Jokinen, E., Kanoni, S., Kristiansson, K. & 256 others, , 23 Nov 2016, In: Nature Communications. 7, 11 p., 13357.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology
Schnurr, T. M., Gjesing, A. M. P., Sandholt, C. H., Jonsson, Anna Elisabet, Mahendran, Y., Have, C. T., Ekstrøm, Claus Thorn, Bjerregaard, A., Brage, S., Witte, D., Jørgensen, M. E., Aadahl, Mette, Thuesen, B. H., Linneberg, Allan René, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye, Grarup, Niels, Kilpeläinen, Tuomas O. & Hansen, Torben, 15 Nov 2016, In: P L o S One. 11, 11, 14 p., e0166738.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease
Scott, R. A., Freitag, D. F., Li, L., Chu, A. Y., Surendran, P., Young, R., Grarup, N., Stancakova, A., Chen, Y., Varga, T. V., Yaghootkar, H., Luan, J., Zhao, J. H., Willems, S. M., Wessel, J., Wang, S., Maruthur, N., Michailidou, K., Pirie, A., van der Lee, S. J. & 119 others, , 1 Jun 2016, In: Science Translational Medicine. 8, 341, 13 p., 341ra76.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P., Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A., Harakalova, M. & 32 others, , 12 Sep 2016, In: Nature Genetics. 48, 10, p. 1151-1161 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk scores link body fat distribution with specific cardiometabolic profiles
Svendstrup, M., Sandholt, C. H., Andersson Galijatovic, E. A., Linneberg, Allan René, Jørgensen, T., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Grarup, Niels, Hansen, Torben & drb459, drb459, Aug 2016, In: Obesity. 24, 8, p. 1778-1785 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population
Vestmar, M. A., Galijatovic, E. A. A., Christensen, C. R., Pedersen, M. H., Glümer, C., Linneberg, Allan René, Witte, D. R., Jørgensen, M. E., Christensen, C., Brandslund, I., Lauritzen, T., Pedersen, Oluf Borbye, Holst, Birgitte, Grarup, Niels, Schwartz, Thue W. & Hansen, Torben, Sep 2016, In: Journal of Medical Genetics. 53, 9, p. 616-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of the modified Stumvoll Insulin Sensitivity Index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci
Walford, G. A., Gustafsson, S., Rybin, D., Stančáková, A., Chen, H., Liu, C-T., Hong, J., Jensen, R. A., Rice, K., Morris, A. P., Mägi, R., Tönjes, A., Prokopenko, I., Kleber, M. E., Delgado, G., Silbernagel, G., Jackson, A. U., Appel, E. V., Grarup, N., Lewis, J. P. & 59 others, , Oct 2016, In: Diabetes. 65, 10, p. 3200-3211 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Carriers of a VEGFA enhancer polymorphism selectively binding CHOP/DDIT3 are predisposed to increased circulating levels of thyroid-stimulating hormone
Ahluwalia, Tarun Veer Singh, Troelsen, J. T., Balslev-Harder, M., Bork-Jensen, J., Thuesen, B. H., Cerqueira, C., Linneberg, Allan René, Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben & Dalgaard, L. T., Mar 2017, In: Journal of Medical Genetics. 54, 3, p. 166-175 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic determinants of serum vitamin B12 and their relation to body mass index
Allin, K. H., Friedrich, N., Pietzner, M., Grarup, Niels, Thuesen, B. H., Linneberg, Allan René, Pisinger, C., Hansen, Torben, Pedersen, Oluf Borbye & Sandholt, C. H., Feb 2017, In: European Journal of Epidemiology. 32, 2, p. 125–134Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selection in Europeans on fatty acid desaturases associated with dietary changes
Buckley, M. T., Racimo, Fernando, Allentoft, Morten Erik, Jensen, M. K., Jonsson, Anna Elisabet, Huang, H., Hormozdiari, F., Sikora, Martin, Marnetto, D., Eskin, E., Jørgensen, M. E., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Kraft, P., Willerslev, Eske & Nielsen, Rasmus, Jun 2017, In: Molecular Biology and Evolution. 34, 6, p. 1307-1318 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis
Eriksson, J., Haring, R., Grarup, Niels, Vandenput, L., Wallaschofski, H., Lorentzen, E., Hansen, Torben, Mellström, D., Pedersen, Oluf Borbye, Nauck, M., Lorentzon, M., Nystrup Husemoen, L. L., Völzke, H., Karlsson, M., Baumeister, S. E., Linneberg, Allan René & Ohlsson, C., 2017, In: PloS one. 12, 4, 15 p., e0176277.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, , 19 Dec 2017, In: Scientific Data. 4, p. 1-20 20 p., 170179.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urinary metabolomics reveals glycemic and coffee associated signatures of thyroid function in two population-based cohorts
Friedrich, N., Pietzner, M., Cannet, C., Thuesen, B. H., Hansen, Torben, Wallaschofski, H., Grarup, Niels, Skaaby, T., Budde, K., Pedersen, Oluf Borbye, Nauck, M. & Linneberg, Allan René, 2017, In: PLOS ONE. 12, 3, 17 p., e0173078.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Numerous Brugada syndrome-associated genetic variants have no effect on J-point elevation, syncope susceptibility, malignant cardiac arrhythmia, and all-cause mortality
Ghouse, Jonas, Have, C. T., Skov, M. W., Andreasen, Laura Korsholm, Ahlberg, G., Nielsen, J. B., Skaaby, T., Olesen, Søren-Peter, Grarup, Niels, Linneberg, Allan René, Pedersen, Oluf Borbye, drb459, drb459, Haunsø, Stig, Svendsen, Jesper Hastrup, Hansen, Torben, Kanters, Jørgen K. & Olesen, Morten Steen Salling, May 2017, In: Genetics In Medicine. 19, 5, p. 521-528 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus
Gjesing, A. M. P., Rui, G., Lauenborg, J., Have, C. T., Hollensted, M., Andersson, E., Grarup, Niels, Sun, J., Quan, S., Brandslund, I., Damm, Peter, Pedersen, Oluf Borbye, Wang, J. & Hansen, Torben, 2017, In: Endocrine Research. 1, 6, p. 681-690 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 34 others, , 1 Apr 2017, In: PLOS Genetics. 13, 4, e1006528.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function
Jorgensen, S., Have, C. T., Underwood, C. R., Johansen, L. D., Wellendorph, Petrine, Gjesing, A. P., Jorgensen, C. V., Quan, S., Rui, G., Inoue, A., Linneberg, Allan René, Grarup, Niels, Jun, W., Pedersen, Oluf Borbye, Hansen, Torben & Bräuner, Hans, 2017, In: The Journal of Biological Chemistry. 292, 4, p. 1524-1534 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K. L., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A. & 297 others, , 26 Apr 2017, In: Nature Communications. 8, 19 p., 14977.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals
Kraja, A. T., Cook, J. P., Warren, H. R., Surendran, P., Liu, C., Evangelou, E., Manning, A. K., Grarup, N., Drenos, F., Sim, X., Smith, A. V., Amin, N., Blakemore, A. I. F., Bork-Jensen, J., Brandslund, I., Farmaki, A. E., Fava, C., Ferreira, T., Herzig, K. H., Giri, A. & 31 others, , Oct 2017, In: Circulation: Cardiovascular Genetics. 10, 5, 9 p., e001778.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475000 Individuals
Kraja, A. T., Cook, J. P., Warren, H. R., Surendran, P., Liu, C., Evangelou, E., Manning, A. K., Grarup, N., Drenos, F., Sim, X., Smith, A. V., Amin, N., Blakemore, A. I. F., Bork-Jensen, J., Brandslund, I., Farmaki, A-E., Fava, C., Ferreira, T., Herzig, K-H., Giri, A. & 122 others, , Oct 2017, In: Circulation: Cardiovascular Genetics. 10, 5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function
Li, M., Li, Y., Weeks, O., Mijatovic, V., Teumer, A., Huffman, J. E., Tromp, G., Fuchsberger, C., Gorski, M., Lyytikäinen, L-P., Nutile, T., Sedaghat, S., Sorice, R., Tin, A., Yang, Q., Ahluwalia, T. S., Arking, D. E., Bihlmeyer, N. A., Böger, C. A., Carroll, R. J. & 31 others, , 2017, In: Journal of the American Society of Nephrology. 28, 3, p. 981-994 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome-wide association study of plasma lipids in >300,000 individuals
Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Angelantonio, E. DI., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 208 others, , 1 Dec 2017, In: Nature Genetics. 49, 12, p. 1758-1766 9 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels
Mahendran, Y., Jonsson, Anna Elisabet, Have, C. T., Allin, K. H., Witte, D. R., Jørgensen, M. E., Grarup, Niels, Pedersen, Oluf Borbye, Kilpeläinen, Tuomas O. & Hansen, Torben, 10 Feb 2017, In: Diabetologia. 60, 5, p. 873-878 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 243 others, , Dec 2017, In: Diabetes. 66, p. 2019-2032 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Estimation of allele frequency and association mapping using next-generation sequencing data
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Interaction of genetic risk and lifestyle on the incidence of atrial fibrillation
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Identification of novel homozygous variants in FOXE3 and AP4M1 underlying congenital syndromic anophthalmia and microphthalmia
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