Grarup Group

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  1. 2018
  2. Published

    Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

    Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P. & 32 others, Flannick, J., Grarup, Niels, Trubetskoy, V. V., Kravic, J., Kim, Y. J., Rybin, D. V., Yaghootkar, H., Müller-Nurasyid, M., Meidtner, K., Li-Gao, R., Varga, T. V., Marten, J., Li, J., Afzal, Shoaib, Bork-Jensen, J., Tybjærg-Hansen, Anne, Jørgensen, M. E., Jørgensen, T., Kovacs, P., Linneberg, Allan René, Liu, J., Nielsen, S. F., Rode, L., Witte, D. R., Hansen, Torben, Karpe, F., Lind, L., Loos, R. J. F., Nordestgaard, Børge, Pedersen, Oluf Borbye, ExomeBP Consortium, E. C. & V Varga, Tibor, Apr 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

    Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., Li-Gao, R. & 31 others, Lin, H., Liu, C., Lyytikäinen, L., Marten, J., Mei, H., Müller-Nurasyid, M., Orini, M., Padmanabhan, S., Radmanesh, F., Ramirez, J., Robino, A., Schwartz, M., van Setten, J., Smith, A. V., Verweij, N., Warren, H. R., Weiss, S., Alonso, A., Arnar, D. O., Bots, M. L., de Boer, R. A., Dominiczak, A. F., Eijgelsheim, M., Ellinor, P. T., Guo, X., Felix, S. B., Linneberg, Allan René, Pedersen, Oluf Borbye, Hansen, Torben, Kanters, Jørgen K. & et al., E. A., 17 Jul 2018, In: Genome Biology. 19, 17 p., 87.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese

    Graae, A. S., Hollensted, M., Kloppenborg, J. T., Mahendran, Y., Schnurr, T. M., Appel, E. V. R., Rask, J., Nielsen, T. R. H., Johansen, M., Linneberg, Allan René, Jørgensen, M. E., Grarup, Niels, Kadarmideen, H. N., Holst, Birgitte, Pedersen, Oluf Borbye, Holm, Jens-Christian & Hansen, Torben, Aug 2018, In: Diabetologia. 61, 8, p. 1769-1779

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population

    Grarup, Niels, Moltke, Ida, Lepola, Mette Andersen, Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Jørsboe, E., Tiwari, H. K., Hopkins, S. E., Wiener, H. W., Boyer, B. B., Linneberg, Allan René, Pedersen, Oluf Borbye, Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 1 Sep 2018, In: Diabetologia. 61, 9, p. 2005–2015

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2019
  7. Published

    PPARG Pro12Ala Ala carriers exhibit greater improvements in peripheral insulin sensitivity in response to 12 weeks of aerobic exercise training

    Blond, Martin Bæk, Schnurr, T. M., Rasenkilde, M., Quist, Jonas Salling, Gram, A. S., Reichkendler, M. H., Auerbach, P. L., Nordby, P., Skovgaard, Lene Theil, Ribel-Madsen, R., Justesen, Johanne Marie, Kilpeläinen, Tuomas O., Ploug, Thorkil, Stallknecht, Bente Merete & Hansen, Torben, 2019, In: Physiological Genomics. 51, 6, p. 254-260

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria

    Ahluwalia, T. S., Schulz, C-A., Waage, J., Skaaby, T., Sandholm, N., van Zuydam, N., Charmet, R., Bork-Jensen, J., Almgren, P., Thuesen, B. H., Bedin, M., Brandslund, I., Christensen, C. K., Linneberg, A., Ahlqvist, E., Groop, P-H., Hadjadj, S., Tregouet, D-A., Jorgensen, M. E., Grarup, N. & 9 others, Pedersen, Oluf Borbye, Simons, M., Groop, L., Orho-Melander, M., McCarthy, M. I., Melander, O., Rossing, Peter, Kilpeläinen, Tuomas O. & Hansen, Torben, 2019, In: Diabetologia. 62, 2, p. 292-305

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

    Bradfield, J. P., Vogelezang, S., Felix, J. F., Chesi, A., Helgeland, O., Horikoshi, M., Karhunen, V., Lowry, E., Cousminer, D. L., Ahluwalia, T. S., Thiering, E., Boh, E. T-H., Zafarmand, M. H., Vilor-Tejedor, N., Wang, C. A., Joro, R., Chen, Z., Gauderman, W. J., Pitkanen, N., Parra, E. J. & 79 others, Fernandez-Rhodes, L., Alyass, A., Monnereau, C., Curtin, J. A., Have, C. T., McCormack, S. E., Hollensted, M., Frithioff-Bojsoe, C., Valladares-Salgado, A., Peralta-Romero, J., Teo, Y., Standl, M., Leinonen, J. T., Holm, Jens-Christian, Peters, T., Vioque, J., Vrijheid, M., Simpson, A., Custovic, A., Vaudel, M., Canouil, M., Lindi, V., Atalay, M., Kahonen, M., Raitakari, O. T., van Schaik, B. D. C., Berkowitz, R. I., Cole, S. A., Voruganti, V. S., Wang, Y., Highland, H. M., Comuzzie, A. G., Butte, N. F., Justice, A. E., Gahagan, S., Blanco, E., Lehtimaki, T., Lakka, T. A., Hebebrand, J., Bonnefond, A., Grarup, Niels, Froguel, P., Lyytikainen, L., Cruz, M., Kobes, S., Hanson, R. L., Zemel, B. S., Hinney, A., Teo, K. K., Meyre, D., North, K. E., Gilliland, F. D., Bisgaard, H., Bustamante, M., Bønnelykke, Klaus, Pennell, C. E., Rivadeneira, F., Uitterlinden, A. G., Baier, L. J., Vrijkotte, T. G. M., Heinrich, J., Sørensen, Thorkild I.A., Saw, S., Pedersen, Oluf Borbye, Hansen, Torben, Eriksson, J., Widen, E., McCarthy, M. I., Njolstad, P. R., Power, C., Hypponen, E., Sebert, S., Brown, C. D., Jarvelin, M., Timpson, N. J., Johansson, S., Hakonarson, H., Jaddoe, V. W. V. & Grant, S. F. A., 2019, In: Human Molecular Genetics. 28, 19, p. 3327-3338

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations

    Graae, A-S., Grarup, N., Ribel-Madsen, R., Lystbæk, S. H., Boesgaard, T., Staiger, H., Fritsche, A., Wellner, N., Sulek, K., Kjølby, M. F., Backe, M. B., Chubanava, S., Prats, C., Serup, A. K. L., Birk, J. B., Dubail, J., Gillberg, L., Vienberg, S. G., Nykjær, A., Kiens, B. & 10 others, Wojtaszewski, Jørgen F P, Larsen, Steen, Apte, S. S., Häring, H., Vaag, A., Zethelius, B., Pedersen, Oluf Borbye, Treebak, Jonas Thue, Hansen, Torben & Holst, Birgitte, 2019, In: Diabetes. 68, 3, p. 502-514

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Abdominal adiposity and cardiometabolic risk factors in children and adolescents: A Mendelian randomization analysis

    Viitasalo, A., Schnurr, T. M., Pitkänen, N., Hollensted, M., Nielsen, T. R. H., Pahkala, K., Atalay, M., Lind, M. V., Heikkinen, S., Frithioff-Bøjsøe, C., Fonvig, C. E., Grarup, N., Kähönen, M., Carrasquilla, G. D., Larnkjær, A., Pedersen, O., Michaelsen, K. F., Lakka, T. A., Holm, J-C., Lehtimäki, T. & 3 others, Raitakari, O., Hansen, Torben & Kilpeläinen, Tuomas O., 2019, In: American Journal of Clinical Nutrition. 110, 5, p. 1079-1087 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

    Skaaby, T., Kilpeläinen, T. O., Taylor, A. E., Mahendran, Y., Wong, A., Ahluwalia, T. S., Paternoster, L., Trompet, S., Stott, D. J., Flexeder, C., Zhou, A., Brusselle, G., Sajjad, A., Lahousse, L., Tiemeier, H., Have, C. T., Thuesen, B. H., Kårhus, L. L., Møllehave, L. T., Leth-Møller, K. B. & 27 others, Shabanzadeh, D. M., Gonzalez-Quintela, A., Power, C., Hyppönen, E., Kuh, D., Hardy, R., Meitinger, T., Jukema, J. W., Völker, U., Nauck, M., Völzke, H., Friedrich, N., Bonten, T. N., Noordam, R., Mook-Kanamori, D. O., Tolstrup, J. S., Taube, C., Peters, A., Grallert, H., Strauch, K., Schulz, H., Grarup, Niels, Hansen, Torben, Pedersen, Oluf Borbye, Burgess, S., Munafò, M. R. & Linneberg, Allan René, 2019, In: Addiction. 114, 2, p. 216-225 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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