Grarup Group

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  1. Published

    Loci for insulin processing and secretion provide insight into type 2 diabetes risk

    Broadaway, K. A., Yin, X., Williamson, A., Parsons, V. A., Wilson, E. P., Moxley, A. H., Vadlamudi, S., Varshney, A., Jackson, A. U., Ahuja, V., Bornstein, S. R., Corbin, L. J., Delgado, G. E., Dwivedi, O. P., Silva, L. F., Frayling, T. M., Grallert, H., Gustafsson, S., Hakaste, L., Hammar, U. & 51 others, Herder, C., Herrmann, S., Højlund, K., Hughes, D. A., Kleber, M. E., Lindgren, C. M., Liu, C. T., Luan, J., Malmberg, A., Moissl, A. P., Morris, A. P., Perakakis, N., Peters, A., Petrie, J. R., Roden, M., Schwarz, P. E. H., Sharma, S., Silveira, A., Strawbridge, R. J., Tuomi, T., Wood, A. R., Wu, P., Zethelius, B., Baldassarre, D., Eriksson, J. G., Fall, T., Florez, J. C., Fritsche, A., Gigante, B., Hamsten, A., Kajantie, E., Laakso, M., Lahti, J., Lawlor, D. A., Lind, L., März, W., Meigs, J. B., Sundström, J., Timpson, N. J., Wagner, R., Walker, M., Wareham, N. J., Watkins, H., Barroso, I., O'Rahilly, S., Grarup, Niels, Parker, S. C., Boehnke, M., Langenberg, C., Wheeler, E. & Mohlke, K. L., 2023, In: American Journal of Human Genetics. 110, 2, p. 284-299 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Loss of Function Glucose-Dependent Insulinotropic Polypeptide Receptor Variants Are Associated With Alterations in BMI, Bone Strength and Cardiovascular Outcomes

    Kizilkaya, Hüsün Sheyma, Sørensen, Kimmie Vestergaard, Kibsgaard, C. J., Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, wbf943, wbf943, Grarup, Niels & Rosenkilde, Mette, 2021, In: Frontiers in Cell and Developmental Biology. 9, 12 p., 749607.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Loss of sucrase-isomaltase function increases acetate levels and improves metabolic health in Greenlandic cohorts

    Andersen, M. K., Skotte, L., Jørsboe, E., Polito, R., Stæger, F. F., Aldiss, P., Hanghøj, K., Waples, R. K., Santander, C. G., Grarup, N., Dahl-Petersen, I. K., Diaz, L. J., Overvad, M., Senftleber, N. K., Søborg, B., Larsen, C. V. L., Lemoine, C., Pedersen, O., Feenstra, B., Bjerregaard, P. & 9 others, Melbye, M., Jørgensen, M. E., Færgeman, N. J., Koch, A., Moritz, Thomas, Gillum, M. P., Moltke, Ida, Hansen, Torben & Albrechtsen, Anders, 2022, In: Gastroenterology. 162, 4, p. 1171-1182.e3

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

    Flannick, J., Thorleifsson, G., Beer, N. L., Jacobs, S. B. R., Grarup, N., Burtt, N. P., Mahajan, A., Fuchsberger, C., Atzmon, G., Benediktsson, R., Blangero, J., Bowden, D. W., Brandslund, I., Brosnan, J., Burslem, F., Chambers, J., Cho, Y. S., Christensen, C., Douglas, D. A., Duggirala, R. & 31 others, Dymek, Z., Farjoun, Y., Fennell, T., Fontanillas, P., Forsén, T., Gabriel, S., Glaser, B., Gudbjartsson, D. F., Hanis, C., Hansen, Torben, Hreidarsson, A. B., Hveem, K., Ingelsson, E., Isomaa, B., Johansson, S., Jørgensen, T., Jørgensen, M. E., Kathiresan, S., Kong, A., Kooner, J., Kravic, J., Laakso, M., Lee, J., Lind, L., Lindgren, C. M., Linneberg, Allan René, Masson, G., Meitinger, T., Ribel-Madsen, R., Pedersen, Oluf Borbye & Go-T2D Consortium, G. C., Apr 2014, In: Nature Genetics. 46, 4, p. 357-63 7 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  5. Published

    Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

    Grarup, Niels, Moltke, Ida, Lepola, Mette Andersen, Dalby, M., Vitting-Seerup, K., Kern, T. S., Mahendran, Y., Jørsboe, E., Larsen, C. V. L., Dahl-Petersen, I. K., Gilly, A., Suveges, D., Dedoussis, G., Zeggini, E., Pedersen, Oluf Borbye, Andersson, Robin, Bjerregaard, P., Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 2018, In: Nature Genetics. 50, 2, p. 172-174 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Low birthweight is associated with a higher incidence of type 2 diabetes over two decades independent of adult BMI and genetic predisposition

    Wibaek, R., Andersen, G. S., Linneberg, Allan René, Hansen, Torben, Grarup, Niels, Thuesen, Anne Cathrine Baun, Jensen, Rasmus Tanderup, Wells, J. C. K., Pilgaard, Kasper Ascanius, Brøns, C., Vistisen, D. & Vaag, Allan, 2023, In: Diabetologia. 66, p. 1669–1679 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

    Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M-F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., Baldridge, A. S. & 31 others, Stančáková, A., Abrol, R., Besse, C., Boland, A., Bork-Jensen, J., Fornage, M., Freitag, D. F., Garcia, M. E., Guo, X., Hara, K., Isaacs, A., Jakobsdottir, J., Lange, L. A., Layton, J. C., Li, M., Hua Zhao, J., Meidtner, K., Morrison, A. C., Nalls, M. A., Peters, M. J., Sabater-Lleal, M., Schurmann, C., Silveira, A., Smith, A. V., Southam, L., Allin, K. H., Jørgensen, T., Linneberg, Allan René, Hansen, Torben, Pedersen, Oluf Borbye & EPIC-InterAct Consortium, E. C., 29 Jan 2015, In: Nature Communications. 6, p. 5897

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification

    Husemoen, L. L. N., Skaaby, T., Jørgensen, T., Thuesen, B. H., Fenger, M., Grarup, Niels, Sandholt, C. H., Hansen, Torben, Pedersen, Oluf Borbye & Linneberg, Allan René, 24 Jan 2014, In: European Journal of Nutrition. 53, 7, p. 1549-59 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans

    Andersson, E. A., Holst, Birgitte, Sparsø, T., Grarup, Niels, Banasik, Karina, Holmkvist, J., Jørgensen, T., Borch-Johnsen, K., Egerod, Kristoffer Lihme, Lauritzen, T., Sørensen, Thorkild I.A., Bonnefond, A., Meyre, D., Froguel, P., Schwartz, Thue W., Pedersen, Oluf Borbye & Hansen, Torben, 2010, In: Diabetes. 59, 6, p. 1539-48 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

    Stokholm, Jakob, Michaelsen, Kim F., Freathy, R. M. & EGG Consortium, E. C., 2019, In: Nature Genetics. 51, 5, p. 804-814

    Research output: Contribution to journal › Journal article › Research › peer-review

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