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The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders
Andersen, M. K., Jørsboe, E., Skotte, L., Hanghøj, K., Sandholt, C. H., Moltke, I., Grarup, N., Kern, T., Mahendran, Y., Søborg, B., Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Tiwari, H. K., Feenstra, B., Koch, A., Wiener, H. W., Hopkins, S. E., Pedersen, O., Melbye, M. & 4 others, , 2020, In: PLOS Genetics. 16, 1, 17 p., e1008544.Research output: Contribution to journal › Journal article › Research › peer-review
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The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals
Grarup, Niels, Overvad, M., Sparsø, T., Witte, D. R., Pisinger, C., Jørgensen, T., Yamauchi, T., Hara, K., Maeda, S., Kadowaki, T., Hansen, T. & Pedersen, Oluf Borbye, 2011, In: Diabetologica. 54, 4, p. 789-94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of GWAS identified BMI loci on changes in body weight among middle-aged danes during a five year period
Sandholt, C. H., Allin, K. H., Toft, U., Borglykke, A., Ribel-Madsen, R., Sparsø, T. H., Justesen, Johanne Marie, Harder, M. N., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 26 Jun 2013, In: Obesity. 22, 3, p. 901-908 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of an extreme and prolonged population bottleneck on patterns of deleterious variation: insights from the Greenlandic Inuit
Pedersen, C. T., Lohmueller, K. E., Grarup, Niels, Bjerregaard, P., Hansen, Torben, Siegismund, Hans Redlef, Moltke, Ida & Albrechtsen, Anders, Feb 2017, In: Genetics. 205, 2, p. 787-801 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of diabetes and the common diabetogenic TBC1D4 p.Arg684Ter variant on cardiovascular risk in Inuit in Greenland
Overvad, M., Diaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Senftleber, N., Grarup, Niels, Hansen, Torben & Jørgensen, M. E., 2020, In: Scientific Reports. 10, 9 p., 22081.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of diabetes and the diabetogenic TBC1D4 p.Arg684ter variant on kidney function in Inuit in Greenland
Overvad, M., Díaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Grarup, Niels, Hansen, Torben, Rossing, Peter & Jørgensen, M. E., 2023, In: International Journal of Circumpolar Health. 82, 8 p., 2191406.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of melatonin on incretin hormones: results from experimental and randomized clinical studies
Lauritzen, E. S., Støy, J., Bæch-Laursen, C., Grarup, Niels, Jessen, N., Hansen, Torben, Møller, N., Hartmann, Bolette, Holst, Jens Juul & Kampmann, U., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 12, p. e5109-e5123 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The frequent UCP2 -866G>A polymorphism protects against insulin resistance and is associated with obesity: a study of obesity and related metabolic traits among 17¿636 Danes
Andersen, G., Dalgaard, L. T., Justesen, Johanne Marie, Anthonsen, S., Nielsen, T., Thørner, L. W., Witte, D., Jørgensen, T., Clausen, J. O., Lauritzen, T., Holmkvist, J., Hansen, Torben & Pedersen, Oluf Borbye, 2012, In: International Journal of Obesity.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic architecture of type 2 diabetes
Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Fernandez Tajes, J., Highland, H. M. & 281 others, , 4 Aug 2016, In: Nature. 536, 7614, p. 41-47 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load
Hornbak, M., Banasik, Karina, Justesen, Johanne Marie, Krarup, N. T., Sandholt, C. H., Andersson, Åsa, Sandbaek, A., Lauritzen, T., Pisinger, C., Witte, D. R., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 6 Jan 2011, In: BMC Medical Genetics. 12, 1, p. 4 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Estimation of allele frequency and association mapping using next-generation sequencing data
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Genome-wide association study of preserved ratio impaired spirometry (PRISm)
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Identification of novel homozygous variants in FOXE3 and AP4M1 underlying congenital syndromic anophthalmia and microphthalmia
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GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal
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