- Published
Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis
Eriksson, J., Haring, R., Grarup, Niels, Vandenput, L., Wallaschofski, H., Lorentzen, E., Hansen, Torben, Mellström, D., Pedersen, Oluf Borbye, Nauck, M., Lorentzon, M., Nystrup Husemoen, L. L., Völzke, H., Karlsson, M., Baumeister, S. E., Linneberg, Allan René & Ohlsson, C., 2017, In: PloS one. 12, 4, 15 p., e0176277.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating Soluble CD163, Associations With Cardiovascular Outcomes and Mortality, and Identification of Genetic Variants in Older Individuals: The Cardiovascular Health Study
Durda, P., Raffield, L. M., Lange, E. M., Olson, N. C., Jenny, N. S., Cushman, M., Deichgraeber, P., Grarup, Niels, Jonsson, Anna Elisabet, Hansen, Torben, Mychaleckyj, J. C., Psaty, B. M., Reiner, A. P., Tracy, R. P. & Lange, L. A., 2022, In: Journal of the American Heart Association. 11, 21, 14 p., e024374.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical exome sequencing reveals a novel pathogenic variant in KIF12 underlying cholestasis with highly variable phenotypes
Waheed, N., Waris, R., Naseer, M., Razzaq, A., Suleman, Sufyan & Ullah, A., 2024, In: Clinical Genetics. 105, 1, p. 106-108Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Combinatorial, additive and dose-dependent drug–microbiome associations
Forslund, S. K., Chakaroun, R., Zimmermann-Kogadeeva, M., Markó, L., Aron-Wisnewsky, J., Nielsen, T., Moitinho-Silva, L., Schmidt, T. S. B., Falony, G., Vieira-Silva, S., Adriouch, S., Alves, R. J., Assmann, K., Bastard, J. P., Birkner, T., Caesar, R., Chilloux, J., Coelho, L. P., Fezeu, L., Galleron, N. & 23 others, , 2021, In: Nature. 600, p. 500-517 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined immunotherapy for advanced prostate cancer: Empowering the T cell army.
Suleman, Sufyan & Wei, G., May 2017, In: Asian Journal of Urology.Research output: Contribution to journal › Journal article › Communication
- Published
Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval
Lin, H., van Setten, J., Smith, A. V., Bihlmeyer, N. A., Warren, H. R., Brody, J. A., Radmanesh, F., Hall, L., Grarup, N., Müller-Nurasyid, M., Boutin, T., Verweij, N., Lin, H. J., Li-Gao, R., van den Berg, M. E., Marten, J., Weiss, S., Prins, B. P., Haessler, J., Lyytikäinen, L-P. & 81 others, , 2018, In: Circulation. Genomic and precision medicine. 11, 5, p. 1-11 e002037.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes: a case-control study
Hollensted, M., Ahluwalia, Tarun Veer Singh, Have, C. T., Grarup, Niels, Fonvig, C. E., Nielsen, T. R. H., Trier, C., Paternoster, L., Pedersen, Oluf Borbye, Holm, Jens-Christian, Sørensen, Thorkild I.A. & Hansen, Torben, 2015, In: BMC Medical Genetics. 16, 9 p., 105.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses
pjx571, pjx571, Mahendran, Y., Jonsson, Anna Elisabet, Gjesing, A. P., Weeke, P. E., Jørgensen, M. E., Færch, K., Witte, D. R., Holst, Jens Juul, Jørgensen, T., Grarup, Niels, Pedersen, Oluf Borbye, drb459, drb459, Torekov, Signe Sørensen, Kanters, Jørgen K. & Hansen, Torben, 2018, In: B M C Genetics. 19, 1, p. 1-9 9 p., 15.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population: studies of 7,495 Danish whites
Wegner, L., Andersen, G., Sparsø, T., Grarup, Niels, Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetes. 56, 3, p. 694-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common variation in oxidative phosphorylation genes is not a major cause of insulin resistance or type 2 diabetes
Snogdal, L. S., Wod, M., Grarup, Niels, Vestmar, M., Sparsø, T. H., Jørgensen, T., Lauritzen, T., Beck-Nielsen, H., Henriksen, J. E., Pedersen, Oluf Borbye, Hansen, Torben & Højlund, K., 2012, In: Diabetologia. 55, 2, p. 340-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative analyses of QTLs influencing obesity and metabolic phenotypes in pigs and humans
Pant, S. D., Karlskov-Mortensen, Peter, Jacobsen, M. J., Cirera, Susanna, Kogelman, L., Bruun, Camilla Vibeke Sichlau, Mark, T., Jørgensen, Claus Bøttcher, Grarup, Niels, Appel, E. V. R., Galjatovic, E. A. A., Hansen, T., Pedersen, Oluf Borbye, Guerin, M., Huby, T., Lesnik, P., Meuwissen, T. H. E., Kadarmideen, H. & Fredholm, Merete, 8 Sep 2015, In: PLOS ONE. 10, 9, 22 p., e0137356.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology
Tanigawa, Y., Li, J., Justesen, Johanne Marie, Horn, H., Aguirre, M., DeBoever, C., Chang, C., Narasimhan, B., Lage, K., Hastie, T., Park, C. Y., Bejerano, G., Ingelsson, E. & Rivas, M. A., 2019, In: Nature Communications. 10, 14 p., 4064.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, , 19 Dec 2017, In: Scientific Data. 4, p. 1-20 20 p., 170179.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DeepFake electrocardiograms: the key for open science for artificial intelligence in medicine
Thambawita, V., Isaksen, Jonas L., Hicks, S. A., Ghouse, Jonas, Ahlberg, Gustav, Linneberg, Allan René, Grarup, Niels, Ellervik, Christina, Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., Holstein-Rathlou, N., Strümke, I., Hammer, H. L., Maleckar, M., Halvorsen, P., Riegler, M. A. & Kanters, Jørgen K., 2022, 17 p. (medRxiv).Research output: Working paper › Preprint › Research
- Published
DeepFake electrocardiograms using generative adversarial networks are the beginning of the end for privacy issues in medicine
Thambawita, Vajira Lasantha Bandara, Isaksen, Jonas L., Hicks, S. A., Ghouse, Jonas, Ahlberg, G., Linneberg, Allan René, Grarup, Niels, Ellervik, Christina, Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., Holstein-Rathlou, N., Strümke, I., Hammer, H. L., Maleckar, M. M., Halvorsen, P., Riegler, M. A. & Kanters, Jørgen K., 2021, In: Scientific Reports. 11, 1, 8 p., 21896.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes
Goodrich, J. K., Singer-Berk, M., Son, R., Sveden, A., Wood, J., England, E., Cole, J. B., Weisburd, B., Watts, N., Caulkins, L., Dornbos, P., Koesterer, R., Zappala, Z., Zhang, H., Maloney, K. A., Dahl, A., Aguilar-Salinas, C. A., Atzmon, G., Barajas-Olmos, F., Barzilai, N. & 31 others, , 2021, In: Nature Communications. 12, 15 p., 3505.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes in population isolates: lessons from Greenland
Grarup, Niels, Moltke, Ida, Albrechtsen, Anders & Hansen, Torben, 2015, In: The Review of Diabetic Studies. 12, 3-4, p. 320-329 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes
Ahluwalia, Tarun Veer Singh, Allin, K. H., Sandholt, C. H., Sparsø, T. H., Jørgensen, M. E., Rowe, M., Christensen, C., Brandslund, I., Lauritzen, T., Linneberg, Allan René, Husemoen, L., Jørgensen, T., Hansen, Torben, Grarup, Niels & Pedersen, Oluf Borbye, Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E664-71Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of novel heart rate-associated loci using the Exome Chip
van den Berg, M. E., Warren, H. R., Cabrera, C. P., Verweij, N., Mifsud, B., Haessler, J., Bihlmeyer, N. A., Fu, Y-P., Weiss, S., Lin, H. J., Grarup, N., Li-Gao, R., Pistis, G., Shah, N., Brody, J. A., Müller-Nurasyid, M., Lin, H., Mei, H., Smith, A. V., Lyytikäinen, L-P. & 101 others, , 15 Jun 2017, In: Human Molecular Genetics. 26, 12, p. 2346-2363 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
Surendran, P., Feofanova, E. V., Lahrouchi, N., Ntalla, I., Karthikeyan, S., Cook, J., Chen, L., Mifsud, B., Yao, C., Kraja, A. T., Cartwright, J. H., Hellwege, J. N., Giri, A., Tragante, V., Thorleifsson, G., Liu, D. J., Prins, B. P., Stewart, I. D., Cabrera, C. P., Eales, J. M. & 34 others, , 2020, In: Nature Genetics. 52, 12, p. 1314-1332 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do gene variants influencing adult adiposity affect birth weight? A population-based study of 24 loci in 4,744 Danish individuals
Andersson, E. A., Pilgaard, K., Pisinger, C., Harder, M. N., Grarup, Niels, Færch, K., Sandholt, C., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Pedersen, Oluf Borbye & Hansen, T., 1 Jan 2010, In: P L o S One. 5, 12, p. e14190Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does genetic predisposition to higher fat expandability attenuate the impact of weight gain on cardiometabolic risk?
Carrasquilla, Germán D., Linneberg, Allan René, Jørgensen, T., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2019, In: European Journal of Human Genetics. 27, Suppl. 2, p. 1764 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity
Dallner, O. S., Marinis, J. M., Lu, Y., Birsoy, K., Werner, E., Fayzikhodjaeva, G., Dill, B. D., Molina, H., Moscati, A., Kutalik, Z., Marques-Vidal, P., Kilpeläinen, Tuomas O., Grarup, Niels, Linneberg, Allan René, Zhang, Y., Vaughan, R., Loos, Ruth, Lazar, M. A. & Friedman, J. M., 2019, In: Nature Medicine. 25, 3, p. 507-530 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals
et al., E. A. & Warren, H. R., 25 Jun 2019, In: Journal of the American College of Cardiology. 73, 24, p. 3118-3131Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating narrow-sense heritability using family data from admixed populations
Athanasiadis, G., Speed, D., Lepola, Mette Andersen, Appel, E. V. R., Grarup, Niels, Brandslund, I., Jørgensen, M. E., Larsen, C. V. L., Bjerregaard, P., Hansen, Torben & Albrechtsen, Anders, 2020, In: Heredity. 124, 6, p. 751-762 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Most downloads
-
5481
downloads
Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
5235
downloads
Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2449
downloads
Estimation of allele frequency and association mapping using next-generation sequencing data
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Latest publications
Genome-wide association study of preserved ratio impaired spirometry (PRISm)
Research output: Contribution to journal › Journal article › Research › peer-review
Identification of novel homozygous variants in FOXE3 and AP4M1 underlying congenital syndromic anophthalmia and microphthalmia
Research output: Contribution to journal › Journal article › Research › peer-review
GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal
Research output: Contribution to journal › Journal article › Research › peer-review