- Published
Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease
Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A. B., Norddahl, G. L., Helgadottir, A., Magnusdottir, A., Jonasdottir, A., Gretarsdottir, S., Jonsdottir, I., Steinthorsdottir, V., Rafnar, T., Swinkels, D. W., Galesloot, T. E., Grarup, N., Jørgensen, T., Vestergaard, H., Hansen, T., Lauritzen, T. & 34 others, , 2 Jun 2016, In: New England Journal of Medicine. 374, 22, p. 2131-2141 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals
et al., E. A. & Warren, H. R., 25 Jun 2019, In: Journal of the American College of Cardiology. 73, 24, p. 3118-3131Research output: Contribution to journal › Journal article › Research › peer-review
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Recessive Genome-wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes
O'Connor, M. J., Schroeder, P., Huerta-Chagoya, A., Cortés-Sánchez, P., Bonàs-Guarch, S., Guindo Martínez, Marta, Cole, J. B., Kaur, V., Torrents, D., Veerapen, K., Grarup, Niels, Kurki, M., Friis, Carsten, Pedersen, Oluf Borbye, Brandslund, I., Linneberg, Allan René, Hansen, Torben, Leong, A., Florez, J. C. & Mercader, J. M., 2022, In: Diabetes. 71, 3, p. 554–565Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus
Okamoto, K., Iwasaki, N., Nishimura, C., Doi, K., Noiri, E., Nakamura, S., Takizawa, M., Ogata, M., Fujimaki, R., Grarup, N., Pisinger, C., Borch-Johnsen, K., Lauritzen, T., Sandbaek, A., Hansen, T., Yasuda, K., Osawa, H., Nanjo, K., Kadowaki, T., Kasuga, M. & 5 others, , 2010, In: American Journal of Human Genetics. 86, 1, p. 54-64 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of diabetes and the diabetogenic TBC1D4 p.Arg684ter variant on kidney function in Inuit in Greenland
Overvad, M., Díaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Grarup, Niels, Hansen, Torben, Rossing, Peter & Jørgensen, M. E., 2023, In: International Journal of Circumpolar Health. 82, 8 p., 2191406.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of diabetes and the common diabetogenic TBC1D4 p.Arg684Ter variant on cardiovascular risk in Inuit in Greenland
Overvad, M., Diaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Senftleber, N., Grarup, Niels, Hansen, Torben & Jørgensen, M. E., 2020, In: Scientific Reports. 10, 9 p., 22081.Research output: Contribution to journal › Journal article › Research › peer-review
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A genome-wide association search for type 2 diabetes genes in African Americans
Palmer, N. D., McDonough, C. W., Hicks, P. J., Roh, B. H., Wing, M. R., An, S. S., Hester, J. M., Cooke, J. N., Bostrom, M. A., Rudock, M. E., Talbert, M. E., Lewis, J. P., Ferrara, A., Lu, L., Ziegler, J. T., Sale, M. M., Divers, J., Shriner, D., Adeyemo, A., Rotimi, C. N. & 31 others, , 2012, In: P L o S One. 7, 1, p. e29202Research output: Contribution to journal › Journal article › Research › peer-review
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Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits
CHARGE Consortium Hematology Working Group, C. C. H. W. G., Aug 2016, In: Nature Genetics. 48, 8, p. 867-876 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparative analyses of QTLs influencing obesity and metabolic phenotypes in pigs and humans
Pant, S. D., Karlskov-Mortensen, Peter, Jacobsen, M. J., Cirera, Susanna, Kogelman, L., Bruun, Camilla Vibeke Sichlau, Mark, T., Jørgensen, Claus Bøttcher, Grarup, Niels, Appel, E. V. R., Galjatovic, E. A. A., Hansen, T., Pedersen, Oluf Borbye, Guerin, M., Huby, T., Lesnik, P., Meuwissen, T. H. E., Kadarmideen, H. & Fredholm, Merete, 8 Sep 2015, In: PLOS ONE. 10, 9, 22 p., e0137356.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of an extreme and prolonged population bottleneck on patterns of deleterious variation: insights from the Greenlandic Inuit
Pedersen, C. T., Lohmueller, K. E., Grarup, Niels, Bjerregaard, P., Hansen, Torben, Siegismund, Hans Redlef, Moltke, Ida & Albrechtsen, Anders, Feb 2017, In: Genetics. 205, 2, p. 787-801 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of general health and lifestyle factors with the salivary microbiota – Lessons learned from the ADDITION-PRO cohort
Poulsen, C. S., Nygaard, Nikoline, Constancias, F., Stankevic, Evelina, Kern, T., Witte, D. R., Vistisen, D., Grarup, Niels, Pedersen, Oluf Borbye, Midjord-Belstrøm, Daniel & Hansen, Torben, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 15 p., 1055117.Research output: Contribution to journal › Journal article › Research › peer-review
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Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6
Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., Li-Gao, R. & 31 others, , 17 Jul 2018, In: Genome Biology. 19, 17 p., 87.Research output: Contribution to journal › Journal article › Research › peer-review
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A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
Ramdas, S., Judd, J., Graham, S. E., Kanoni, S., Wang, Y., Surakka, I., Wenz, B., Clarke, S. L., Chesi, A., Wells, A., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K. H. H., Ntalla, I., Hui, Q., Klarin, D. & 32 others, , 2022, In: American Journal of Human Genetics. 109, 8, p. 1366-1387 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Meal sugar-protein balance determines postprandial FGF21 response in humans
Ramne, Stina, Duizer, Lisanne, Nielsen, M. S., Jørgensen, Niklas Rye, Svenningsen, J. S., Grarup, Niels, Sjödin, Anders Mikael, Raben, Anne & Gillum, M. P., 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 5, p. E491-E499Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscle
Ribel-Madsen, R., Poulsen, P., Holmkvist, J., Mortensen, B., Grarup, Niels, Friedrichsen, M., Jørgensen, T., Lauritzen, T., Wojtaszewski, Jørgen F P, Pedersen, Oluf Borbye, Hansen, Torben & Vaag, Allan, 2010, In: Diabetes. 59, 4, p. 1108-1112 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
Ried, J. S., Jeff M, J., Chu, A. Y., Bragg-Gresham, J. L., van Dongen, J., Huffman, J. E., Ahluwalia, T. V. S., Cadby, G., Eklund, N., Eriksson, J., Esko, T., Feitosa, M. F., Goel, A., Gorski, M., Hayward, C., Heard-Costa, N. L., Jackson, A. U., Jokinen, E., Kanoni, S., Kristiansson, K. & 256 others, , 23 Nov 2016, In: Nature Communications. 7, 11 p., 13357.Research output: Contribution to journal › Journal article › Research › peer-review
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A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads
Rose, C. S., Grarup, Niels, Krarup, N. T., Poulsen, P., Wegner, L., Nielsen, T., Banasik, Karina, Faerch, K., Andersen, G., Albrechtsen, Anders, Borch-Johnsen, K., Clausen, J. O., Jørgensen, T., Vaag, Allan, Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: Diabetologia. 52, 10, p. 2122-2129 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Abdominal visceral and subcutaneous adipose tissue and associations with cardiometabolic risk in Inuit, Africans and Europeans: a cross-sectional study
Rønn, P. F., Andersen, G. S., Lauritzen, T., Christensen, Dirk Lund, Aadahl, Mette, Carstensen, Bendix, Grarup, Niels & Jørgensen, M. E., 14 Sep 2020, In: BMJ Open. 10, 9, 11 p., e038071.Research output: Contribution to journal › Journal article › Research › peer-review
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Associations between birth weight and glucose intolerance in adulthood among Greenlandic Inuit
Rønn, P. F., Jørgensen, M. E., Smith, L. S., Bjerregaard, P., Dahl-Petersen, I. K., Larsen, C. V. L., Grarup, Niels & Andersen, G. S., 2019, In: Diabetes Research and Clinical Practice. 150, p. 129-137 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association studies of human adiposity: Zooming in on synapses.
Sandholt, C. H., Grarup, Niels, Pedersen, Oluf Borbye & Hansen, Torben, 2015, In: Molecular and Cellular Endocrinology. 418, Part 2, p. 90-100 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of GWAS identified BMI loci on changes in body weight among middle-aged danes during a five year period
Sandholt, C. H., Allin, K. H., Toft, U., Borglykke, A., Ribel-Madsen, R., Sparsø, T. H., Justesen, Johanne Marie, Harder, M. N., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 26 Jun 2013, In: Obesity. 22, 3, p. 901-908 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
Saxena, R., Hivert, M-F., Langenberg, C., Tanaka, T., Pankow, J. S., Vollenweider, P., Lyssenko, V., Bouatia-Naji, N., Dupuis, J., Jackson, A. U., Kao, W. H. L., Li, M., Glazer, N. L., Manning, A. K., Luan, J., Stringham, H. M., Prokopenko, I., Johnson, T., Grarup, N., Boesgaard, T. W. & 31 others, , 1 Feb 2010, In: Nature Genetics. 42, 2, p. 142-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study
Schmidt, A. F., Swerdlow, D. I., Holmes, M. V., Patel, R. S., Fairhurst-Hunter, Z., Lyall, D. M., Hartwig, F. P., Horta, B. L., Hyppönen, E., Power, C., Moldovan, M., van Iperen, E., Hovingh, G. K., Demuth, I., Norman, K., Steinhagen-Thiessen, E., Demuth, J., Bertram, L., Liu, T., Coassin, S. & 31 others, , Feb 2017, In: The Lancet Diabetes & Endocrinology. 5, 2, p. 97–105Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
Schmidt, A. F., Holmes, M. V., Preiss, D., Swerdlow, D. I., Denaxas, S., Fatemifar, G., Faraway, R., Finan, C., Valentine, D., Fairhurst-Hunter, Z., Hartwig, F. P., Horta, B. L., Hypponen, E., Power, C., Moldovan, M., Van Iperen, E., Hovingh, K., Demuth, I., Norman, K., Steinhagen-Thiessen, E. & 145 others, , 2019, In: BMC Cardiovascular Disorders. 19, 1, 10 p., 240.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interactions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD
Schnurr, T. M., Katz, S. F., Justesen, Johanne Marie, O'Sullivan, J. W., Saliba-Gustafsson, P., Assimes, T. L., Carcamo-Orive, I., Ahmed, A., Ashley, E. A., Hansen, Torben & Knowles, J. W., 2022, In: Hepatology Communications. 6, 7, p. 1516-1526Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Estimation of allele frequency and association mapping using next-generation sequencing data
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Genome-wide association study of preserved ratio impaired spirometry (PRISm)
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Identification of novel homozygous variants in FOXE3 and AP4M1 underlying congenital syndromic anophthalmia and microphthalmia
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GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal
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