- 2021
- Published
Large-scale association analyses identify host factors influencing human gut microbiome composition
Kurilshikov, A., Medina-Gomez, C., Bacigalupe, R., Radjabzadeh, D., Wang, J., Demirkan, A., Le Roy, C. I., Raygoza Garay, J. A., Finnicum, C. T., Liu, X., Zhernakova, D. V., Bonder, M. J., Hansen, T. H., Frost, F., Rühlemann, M. C., Turpin, W., Moon, J. Y., Kim, H. N., Lüll, K., Barkan, E. & 84 others, , 2021, In: Nature Genetics. 53, p. 156-165 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, , 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism
Jensen, B. A. H., Holm, J. B., Larsen, I. S., von Burg, N., Derer, S., Sonne, S. B., Pærregaard, S. I., Damgaard, M. V., Indrelid, S. A., Rivollier, A., Agrinier, A. L., Sulek, K., Arnoldussen, Y. J., Fjære, E., Marette, A., Angell, I. L., Rudi, K., Treebak, J. T., Madsen, L., Åkesson, C. P. & 5 others, , 2021, In: Nature Communications. 12, 19 p., 1093.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mapping the human genetic architecture of COVID-19
Niemi, M. E. K., Karjalainen, J., Liao, R. G., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Andrews, S. J., Kanai, M., Veerapen, K., Fernandez-Cadenas, I., Schulte, E. C., Striano, P., Marttila, M., Minica, C., Marouli, E., Karim, M. A., Wendt, F. R., Savage, J., Sloofman, L. & 41 others, , 2021, In: Nature. 600, p. 472-477Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-linear interaction between physical activity and polygenic risk score of body mass index in Danish and Russian populations
Borisevich, D., Schnurr, T. M., pjx571, pjx571, Rakitko, A., Ängquist, Lars, Ilinsky, V., Aadahl, Mette, Grarup, Niels, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Hansen, Torben, 2021, In: PLoS ONE. 16, 10, 16 p., e0258748.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: Overlapping Mechanisms
Møller, Søren, Kimer, N., Kronborg, T., Grandt, J., Hove, Jens Dahlgaard, Barløse, Mads Christian Johannes & Gluud, Lise Lotte, 2021, In: Seminars in Liver Disease. 41, 03, p. 235-247Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel Anti-inflammatory Treatments in Cirrhosis. A Literature-Based Study
Kronborg, T. M., Lambert, Henriette Ytting, Hobolth, L., Møller, Søren & Kimer, N., 2021, In: Frontiers in Medicine. 8, 718896.Research output: Contribution to journal › Review › Research › peer-review
- Published
Obesity treatment effect in Danish children and adolescents carrying Melanocortin-4 Receptor mutations
Trier, C., Hollensted, M., Schnurr, T. M., Lund, Morten Asp Vonsild, Nielsen, T. R. H., Rui, G., Andersson, E. A., Svendstrup, M., Bille, D. S., Gjesing, A. P., Fonvig, Cilius Esmann, Frithioff-Bojsoe, C., Balslev-Harder, M., Quan, S., Gamborg, Michael Orland, Pedersen, Oluf Borbye, Ängquist, Lars, Holm, Jens-Christian & Hansen, Torben, 2021, In: International Journal of Obesity. 45, p. 66-76 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers
Schnurr, T. M., Jørsboe, E., Chadt, A., Dahl-Petersen, I. K., Kristensen, Jonas Møller, Wojtaszewski, Jørgen F P, Springer, C., Bjerregaard, P., Brage, S., Pedersen, Oluf Borbye, Moltke, Ida, Grarup, Niels, Al-Hasani, H., Albrechtsen, Anders, Jørgensen, M. E. & Hansen, Torben, 2021, In: Diabetologia. 64, p. 1795-1804Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population-based pediatric reference values for serum parathyroid hormone, vitamin D, calcium, and phosphate in Danish/North-European white children and adolescents
Vissing Landgrebe, A., Lund, Morten Asp Vonsild, Lausten-Thomsen, U., Frithioff-Bøjsøe, C., Fonvig, Cilius Esmann, Lind Plesner, J., Aas Holm, L., Jespersen, Thomas, Hansen, Torben & Holm, Jens-Christian, 2021, In: Clinica Chimica Acta. 523, p. 483-490Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study
Bizzotto, R., Jennison, C., Jones, A. G., Kurbasic, A., Tura, A., Kennedy, G., Bell, J. D., Thomas, E. L., Frost, G., Eriksen, R., Koivula, R. W., Brage, S., Kaye, J., Hattersley, A. T., Heggie, A., McEvoy, D., 't Hart, L. M., Beulens, J. W., Elders, P., Musholt, P. B. & 28 others, , 2021, In: Diabetes Care. 44, 2, p. 511-518 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Profiles of glucose metabolism in different prediabetes phenotypes, classified by fasting glycemia, 2-hour OGTT, glycated hemoglobin, and 1-hour OGTT: An IMI DIRECT study
Tura, A., Grespan, E., Göbl, C. S., Koivula, R. W., Franks, P. W., Pearson, E. R., Walker, M., Forgie, I. M., Giordano, G. N., Pavo, I., Ruetten, H., Dermitzakis, E. T., McCarthy, M. I., Pedersen, O., Schwenk, J. M., Adamski, J., De Masi, F., Tsirigos, K. D., Brunak, S., Viñuela, A. & 17 others, , 2021, In: Diabetes. 70, 6, db210227.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prognostic performance of 7 biomarkers compared to liver biopsy in early alcohol-related liver disease
Rasmussen, D. N., Thiele, M., Johansen, S., Kjærgaard, M., Lindvig, K. P., Israelsen, M., Antonsen, S., Detlefsen, S., Krag, A., Anastasiadou, E., Arumugam, M., Bork, P., Hansen, T., Hartoft, C., Israelsen, H., Karsdal, M., Legido-Quigley, C., Melberg, H. O., Trebicka, J., Mann, M. & 2 others, , 2021, In: Journal of Hepatology. 75, 5, p. 1017-1025 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein intake, metabolic status and the gut microbiota in different ethnicities: Results from two independent cohorts
Bel Lassen, P., Attaye, I., Adriouch, S., Nicolaou, M., Aron-Wisnewsky, J., Nielsen, T., Chakaroun, R., Le Chatelier, E., Forslund, S., Belda, E., Bork, P., Bäckhed, F., Stumvoll, M., Pedersen, O., Herrema, H., Groen, A. K., Pinto-Sietsma, S. J., Zwinderman, A. H., Nieuwdorp, M., Clement, K. & 1 others, , 2021, In: Nutrients. 13, 9, 3159.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply to: “Dietary sucrose induces atherosclerotic diseases more than dietary fat in LDLr−/− ApoB100/100 mice: Is it independent of differences in plasma cholesterol levels?”
Perazza, L. R., Daniel, N., Mitchell, P. L., Jensen, Benjamin Anderschou Holbech & Marette, A., 2021, In: Atherosclerosis. 325, p. 118-120 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Revision rates of trapeziometacarpal total joint arthroplasty in relation to occupational hand force requirements
Kirkeby, L., Frost, Poul, Svendsen, S. W. & Hansen, Torben, 2021, In: Journal of Hand Surgery: European Volume. 46, 9, p. 968-974 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of melatonin on incretin hormones: results from experimental and randomized clinical studies
Lauritzen, E. S., Støy, J., Bæch-Laursen, C., Grarup, Niels, Jessen, N., Hansen, Torben, Møller, N., Hartmann, Bolette, Holst, Jens Juul & Kampmann, U., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 12, p. e5109-e5123 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study
Eloranta, A-M., Sallinen, T., Viitasalo, A., Lintu, N., Väistö, J., Jalkanen, H., Tompuri, T. T., Soininen, S., Haapala, E. A., Kiiskinen, S., Schnurr, T. M., Kilpeläinen, T. O., Mikkonen, S., Savonen, K., Atalay, M., Brage, S., Laaksonen, D. E., Lindi, V., Ågren, J., Schwab, U. & 2 others, , 2021, In: European Journal of Nutrition. 60, p. 425-434Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic history of Greenlandic-European contact
Waples, R. K., Hauptmann, A. L., Seiding, I. H., Jørsboe, E., Jørgensen, M. E., Grarup, Niels, Andersen, M. K., Larsen, C. V. L., Bjerregaard, P., Hellenthal, G., Hansen, Torben, Albrechtsen, Anders & Moltke, Ida, 2021, In: Current Biology. 31, 10, p. 2214-2219.e4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The power of genetic diversity in genome-wide association studies of lipids
Graham, S. E., Clarke, S. L., Wu, K-H. H., Kanoni, S., Zajac, G. J. M., Ramdas, S., Surakka, I., Ntalla, I., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Hwang, M. Y., Han, S., Narita, A., Choudhury, A., Bentley, A. R., Ekoru, K., Verma, A., Trivedi, B. & 504 others, , 2021, In: Nature. 600, p. 675-679Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of a traditional and western diet on glucose homeostasis in Greenlandic Inuit carriers and non-carriers of type 2 diabetes variant in the TBC1D4 gene: A protocol for a randomized clinical trial
Møller, G., Lind, M. V., Hauptmann, A. L., Senftleber, N., Hansen, C. B., Hansen, Torben, Jørgensen, M. E. & Lauritzen, Lotte, 2021, In: Contemporary Clinical Trials Communications. 21, 6 p., 100734.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The trans-ancestral genomic architecture of glycemic traits
Chen, J., Spracklen, C. N., Marenne, G., Varshney, A., Corbin, L. J., Luan, J., Willems, S. M., Wu, Y., Zhang, X., Horikoshi, M., Boutin, T. S., Magi, R., Waage, J., Li-Gao, R., Chan, K. H. K., Yao, J., Anasanti, M. D., Chu, A. Y., Claringbould, A., Heikkinen, J. & 31 others, , 2021, In: Nature Genetics. 53, 6, p. 840-860 41 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trans-ethnic gut microbial signatures of prediabetic subjects from India and Denmark
Pinna, N. K., Anjana, R. M., Saxena, S., Dutta, A., Gnanaprakash, V., Rameshkumar, G., Aswath, S., Raghavan, S., Rani, C. S. S., Radha, V., Balasubramanyam, M., Pant, A., Nielsen, T., Jørgensen, T., Færch, K., Kashani, A., Silva, M. C. A., Vestergaard, H., Hansen, T. H., Hansen, T. & 6 others, , 2021, In: Genome Medicine. 13, 20 p., 36.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trans-ethnic gut microbiota signatures of type 2 diabetes in Denmark and India
Alvarez-Silva, C., Kashani, A., Hansen, T. H., Pinna, N. K., Anjana, R. M., Dutta, A., Saxena, S., Støy, J., Kampmann, U., Nielsen, T., Jørgensen, T., Gnanaprakash, V., Gnanavadivel, R., Sukumaran, A., Rani, C. S. S., Færch, K., Radha, V., Balasubramanyam, M., Nair, G. B., Das, B. & 6 others, , 2021, In: Genome Medicine. 13, 37.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome analysis uncover differential regulation in cell cycle, immunity, and metabolism in Anopheles albimanus during immune priming with Plasmodium berghei
Maya-Maldonado, K., Cime-Castillo, J., Maya, Otoniel, Argotte-Ramos, R., Rodríguez, M. C. & Lanz-Mendoza, H., 2021, In: Developmental and Comparative Immunology. 120, 104046.Research output: Contribution to journal › Journal article › Research › peer-review
Most downloads
-
5492
downloads
Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
5241
downloads
Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2449
downloads
Estimation of allele frequency and association mapping using next-generation sequencing data
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Latest publications
A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels
Research output: Contribution to journal › Journal article › Research › peer-review
Interaction of genetic risk and lifestyle on the incidence of atrial fibrillation
Research output: Contribution to journal › Journal article › Research › peer-review
Genome-wide association study of preserved ratio impaired spirometry (PRISm)
Research output: Contribution to journal › Journal article › Research › peer-review