- Published
Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study
Wesolowska-Andersen, A., Brorsson, C. A., Bizzotto, R., Mari, A., Tura, A., Koivula, R., Mahajan, A., Vinuela, A., Tajes, J. F., Sharma, S., Haid, M., Prehn, C., Artati, A., Hong, M. G., Musholt, P. B., Kurbasic, A., Masi, F. D., Tsirigos, K., Pedersen, H. K., Gudmundsdottir, V. & 31 others, , 2022, In: Cell Reports Medicine. 3, 1, 25 p., 100477.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fragmentation of Human Neutrophil α-Defensin 4 to Combat Multidrug Resistant Bacteria
Ehmann, D., Koeninger, L., Wendler, J., Malek, N. P., Stange, E. F., Wehkamp, J. & Jensen, Benjamin Anderschou Holbech, 2020, In: Frontiers in Microbiology. 11, 10 p., 1147.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional Screening Identifies miRNAs Influencing Apoptosis and Proliferation in Colorectal Cancer
Christensen, L. L., Holm, A., Rantala, J., Kallioniemi, O., Rasmussen, M. H., Ostenfeld, M. S., Dagnaes-Hansen, F., Oster, B., Schepeler, T., Tobiasen, H., Thorsen, K., Sieber, O. M., Gibbs, P., Lamy, P., Hansen, T. F., Jakobsen, A., Riising, E. M., Helin, K., Lubinski, J., Hagemann-Madsen, R. & 3 others, , 2014, In: PLOS ONE. 9, 6, p. e96767Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population
Vestmar, M. A., Galijatovic, E. A. A., Christensen, C. R., Pedersen, M. H., Glümer, C., Linneberg, Allan René, Witte, D. R., Jørgensen, M. E., Christensen, C., Brandslund, I., Lauritzen, T., Pedersen, Oluf Borbye, Holst, Birgitte, Grarup, Niels, Schwartz, Thue W. & Hansen, Torben, Sep 2016, In: Journal of Medical Genetics. 53, 9, p. 616-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fungal lysozyme leverages the gut microbiota to curb DSS-induced colitis
Larsen, I. S., Jensen, Benjamin Anderschou Holbech, Bonazzi, E., Choi, Beatrice So-Yun, Kristensen, N. N., Schmidt, E. G. W., Süenderhauf, A., Morin, L., Olsen, P. B., Hansen, L. B. S., Schröder, T., Sina, C., Chassaing, B. & Marette, A., 2021, In: Gut Microbes. 13, 1, 20 p., 1988836.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans
Sparsø, T., Bonnefond, A., Andersson, E., Bouatia-Naji, N., Holmkvist, J., Wegner, L., Grarup, N., Gjesing, A. P., Banasik, K., Cavalcanti-Proença, C., Marchand, M., Vaxillaire, M., Charpentier, G., Jarvelin, M-R., Tichet, J., Balkau, B., Marre, M., Lévy-Marchal, C., Faerch, K., Borch-Johnsen, K. & 36 others, , 2009, In: Diabetes. 58, 6, p. 1450-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst
Zylicz, Jan Jakub, Borensztein, M., Wong, F. C. K., Huang, Yun, Lee, C., Dietmann, S. & Surani, M. A., 10 May 2018, In: eLife. 7, e33361.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in HNF1A Diabetes
Christensen, A. S., Haedersdal, S., Storgaard, H., Rose, K., Hansen, N. L., Holst, Jens Juul, Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2019, In: Diabetes. 68, Suppl. 1, 1 p., 981-P.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in Hepatocyte Nuclear Factor 1 alpha Mutation Carriers
Christensen, A. S., Haedersdal, S., Storgaard, H., Rose, K., Hansen, N. L., Holst, Jens Juul, Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetes. 69, 9, p. 1989-2002 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 Receptor Agonist Treatment in Morbid Obesity and Type 2 Diabetes Due to Pathogenic Homozygous Melanocortin-4 Receptor Mutation: A Case Report
Iepsen, E. W., Have, C. T., Veedfald, Simon, Madsbad, Sten, Holst, Jens Juul, Grarup, Niels, Pedersen, Oluf Borbye, Brandslund, I., Holm, Jens-Christian, Hansen, Torben & Torekov, Signe Sørensen, 2020, In: Cell Reports Medicine. 1, 1, 8 p., 100006.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women
Iepsen, E. P. W., Lundgren, J. R., Hartmann, Bolette, Pedersen, Oluf Borbye, Hansen, Torben, Jørgensen, Niklas Rye, Jensen, J. B., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2015, In: The Journal of clinical endocrinology and metabolism. 100, 8, p. 2909 –2917 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal
Senftleber, N. K., Andersen, M. K., Jørsboe, E., Stæger, Frederik Filip Vinggaard, Nøhr, A. K., Garcia Erill, Genís, Meisner, Jonas, Santander, Cindy, Balboa, Renzo Fidel Ferdinando, Gilly, A., Bjerregaard, P., Larsen, C. V. L., Grarup, Niels, Jørgensen, M. E., Zeggini, E., Moltke, Ida, Hansen, Torben & Albrechtsen, Anders, 2024, In: European Journal of Human Genetics. 32, p. 215–223 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gain-of-function mutation in the voltage-gated potassium channel gene KCNQ1 and glucose-stimulated hypoinsulinemia - case report
Zhang, J., Juhl, C. R., Hylten-Cavallius, L., Olesen, Morten Steen Salling, Linneberg, Allan René, Holst, Jens Juul, Hansen, Torben, Kanters, Jørgen K. & Torekov, Signe Sørensen, 2020, In: B M C Endocrine Disorders. 20, 5 p., 38.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene x Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry
Ahmad, S., Rukh, G., Varga, T. V., Ali, A., Kurbasic, A., Shungin, D., Ericson, U., Koivula, R. W., Chu, A. Y., Rose, L. M., Ganna, A., Qi, Q., Stancakova, A., Sandholt, C. H., Elks, C. E., Curhan, G., Jensen, M. K., Tamimi, R. M., Allin, K. H., Jorgensen, T. & 26 others, , Jul 2013, In: PLOS Genetics. 9, 7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry
Ahmad, S., Rukh, G., Varga, T. V., Ali, A., Kurbasic, A., Shungin, D., Ericson, U., Koivula, R. W., Chu, A. Y., Rose, L. M., Ganna, A., Qi, Q., Stančáková, A., Sandholt, C. H., Elks, C. E., Curhan, G., Jensen, M. K., Tamimi, R. M., Allin, K. H., Jørgensen, T. & 27 others, , Jul 2013, In: P L o S Genetics (Online). 9, 7, p. e1003607Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study
Langenberg, C., Sharp, S. J., Franks, P. W., Scott, R. A., Deloukas, P., Forouhi, N. G., Froguel, P., Groop, L. C., Hansen, T., Palla, L., Pedersen, O., Schulze, M. B., Tormo, M-J., Wheeler, E., Agnoli, C., Arriola, L., Barricarte, A., Boeing, H., Clarke, G. M., Clavel-Chapelon, F. & 27 others, , 2014, In: P L o S Medicine (Print). 11, 5, 14 p., e1001647.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology
Schnurr, T. M., Gjesing, A. M. P., Sandholt, C. H., Jonsson, Anna Elisabet, Mahendran, Y., Have, C. T., Ekstrøm, Claus Thorn, Bjerregaard, A., Brage, S., Witte, D., Jørgensen, M. E., Aadahl, Mette, Thuesen, B. H., Linneberg, Allan René, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye, Grarup, Niels, Kilpeläinen, Tuomas O. & Hansen, Torben, 15 Nov 2016, In: P L o S One. 11, 11, 14 p., e0166738.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation
Weng, L. C., Hall, A. W., Choi, S. H., Jurgens, S. J., Haessler, J., Bihlmeyer, N. A., Grarup, N., Lin, H., Teumer, A., Li-Gao, R., Yao, J., Guo, X., Brody, J. A., Müller-Nurasyid, M., Schramm, K., Verweij, N., van den Berg, M. E., van Setten, J., Isaacs, A., Ramírez, J. & 40 others, , 2020, In: Circulation. Genomic and precision medicine. 13, 5, p. 387-395 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Determinants of Weight Loss After Bariatric Surgery
Aasbrenn, M., Schnurr, T. M., Have, C. T., Svendstrup, M., Hansen, D. L., Worm, Dorte, Balslev-Harder, M., Hollensted, M., Grarup, Niels, Burgdorf, K. S., drb459, drb459, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A., Fenger, M., Madsbad, Sten & Hansen, Torben, 2019, In: Obesity Surgery. 29, 8, p. 2554-2561 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Loss of Sucrase-Isomaltase Function: Mechanisms, Implications, and Future Perspectives
Senftleber, N. K., Ramne, Stina, Moltke, Ida, Jørgensen, M. E., Albrechtsen, Anders, Hansen, Torben & Lepola, Mette Andersen, 2023, In: Application of Clinical Genetics. 16, p. 31-39 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Genetic Predictors of Change in Waist Circumference and Waist-to-Hip Ratio With Lifestyle Intervention: The Trans-NIH Consortium for Genetics of Weight Loss Response to Lifestyle Intervention
McCaffery, J. M., Jablonski, K. A., Pan, Q., Astrup, A., Christiansen, Malene Revsbech, Corella, D., Corso, L. M. L., Florez, J. C., Franks, P. W., Gardner, C., Hansen, Torben, Kilpeläinen, Tuomas O., Knowler, W. C., Lindström, J., Saris, W. H. M., Sørensen, Thorkild I.A., Tuomilehto, J., Uusitupa, M., Wing, R. R. & Agurs-Collins, T., 2022, In: Diabetes. 71, 4, p. 669-676 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity
Yaghootkar, H., Zhang, Y., Spracklen, C. N., Karaderi, T., Huang, L. O., Bradfield, J., Schurmann, C., Fine, R. S., Preuss, M. H., Kutalik, Z., Wittemans, L. B., Lu, Y., Metz, S., Willems, S. M., Li-Gao, R., Grarup, N., Wang, S., Molnos, S., Sandoval-Zárate, A. A., Nalls, M. A. & 32 others, , 2020, In: Diabetes. 69, 11, 93 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Susceptibility for Childhood BMI has no Impact on Weight Loss Following Lifestyle Intervention in Danish Children
Hollensted, M., Fogh, M., Schnurr, T. M., Kloppenborg, J. T., Have, C. T., Nielsen, T. R. H., Rask, J., Lund, Morten Asp Vonsild, Frithioff-Bøjsøe, C., Østergaard Johansen, M., Vincent Rosenbaum Appel, E., Mahendran, Y., Grarup, Niels, Kadarmideen, H. N., Pedersen, Oluf Borbye, Holm, Jens-Christian & Hansen, Torben, 2018, In: Obesity. 26, 12, p. 1915-1922 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variant SLC2A2 Is Associated with Risk of Cardiovascular Disease - Assessing the Individual and Cumulative Effect of 46 Type 2 Diabetes Related Genetic Variants
Borglykke, A., Grarup, Niels, Sparsø, T., Linneberg, Allan René, Fenger, M., Jeppesen, J., Hansen, Torben, Pedersen, Oluf Borbye & Jørgensen, T., 2012, In: P L o S One. 7, 11, p. e50418Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function
Jorgensen, S., Have, C. T., Underwood, C. R., Johansen, L. D., Wellendorph, Petrine, Gjesing, A. P., Jorgensen, C. V., Quan, S., Rui, G., Inoue, A., Linneberg, Allan René, Grarup, Niels, Jun, W., Pedersen, Oluf Borbye, Hansen, Torben & Bräuner, Hans, 2017, In: The Journal of Biological Chemistry. 292, 4, p. 1524-1534 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Most downloads
-
5481
downloads
Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
5236
downloads
Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2449
downloads
Estimation of allele frequency and association mapping using next-generation sequencing data
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Latest publications
Genome-wide association study of preserved ratio impaired spirometry (PRISm)
Research output: Contribution to journal › Journal article › Research › peer-review
Variants at the Interleukin 1 Gene Locus and Pericarditis
Research output: Contribution to journal › Journal article › Research › peer-review
Change in abdominal obesity after colon cancer surgery – effects of left-sided and right-sided colonic resection
Research output: Contribution to journal › Journal article › Research › peer-review