- 2013
- Published
Genetic risk score of 46 type 2 diabetes risk variants associates with changes in plasma glucose and estimates of pancreatic beta-cell function over 5 years of follow-up
Galijatovic, E. A. A., Allin, K. H., Sandholt, C. H., Borglykke, A., Lau, C. J., Ribel-Madsen, R., Sparsø, T., Justesen, Johanne Marie, Harder, M. N., Jørgensen, M. E., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 8 Jul 2013, In: Diabetes. 62, 10, p. 3610 3617 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does DNA Methylation of PPARGC1A Influence Insulin Action in First Degree Relatives of Patients with Type 2 Diabetes?
Gillberg, L., Jacobsen, S., Ribel-Madsen, R., Gjesing, A. M. P., Boesgaard, T. W., Ling, C., Pedersen, Oluf Borbye, Hansen, Torben & Vaag, Allan, 2013, In: P L o S One. 8, 3, p. e58384Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Grarup, N., Sulem, P., Sandholt, C. H., Thorleifsson, G., Ahluwalia, T. V. S., Steinthorsdottir, V., Bjarnason, H., Gudbjartsson, D. F., Magnusson, O. T., Sparsø, T., Albrechtsen, A., Kong, A., Masson, G., Tian, G., Cao, H., Nie, C., Kristiansen, K., Husemoen, L. L., Thuesen, B., Li, Y. & 10 others, , 2013, In: P L o S Genetics. 9, 6, 12 p., e1003530.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 2 Diabetes Risk Alleles Near BCAR1 and in ANK1 Associate With Decreased ß-Cell Function Whereas Risk Alleles Near ANKRD55 and GRB14 Associate With Decreased Insulin Sensitivity in the Danish Inter99 Cohort
Harder, M. N., Ribel-Madsen, R., Justesen, Johanne Marie, Sparsø, T., Galijatovic, E. A. A., Grarup, Niels, Jørgensen, T., Linneberg, Allan René, Hansen, Torben & Pedersen, Oluf Borbye, 1 Apr 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 4, p. 801-806Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism
Horikoshi, M., Yaghootkar, H., Mook-Kanamori, D. O., Sovio, U., Taal, H. R., Hennig, B. J., Bradfield, J. P., St Pourcain, B., Evans, D. M., Charoen, P., Kaakinen, M., Cousminer, D. L., Lehtimäki, T., Kreiner-Møller, E., Warrington, N. M., Bustamante, M., Feenstra, B., Berry, D. J., Thiering, E., Pfab, T. & 31 others, , 2013, In: Nature Genetics. 45, 1, p. 76-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin Resistance and Impaired Pancreatic β-Cell Function in Adult Offspring of Women With Diabetes in Pregnancy
Kelstrup, L., Damm, Peter, Mathiesen, Elisabeth, Hansen, Torben, Vaag, Allan, Pedersen, Oluf Borbye & Clausen, Tine Dalsgaard, 2013, In: The Journal of clinical endocrinology and metabolism. 98, 9, p. 3793-3801 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance and impaired pancreatic beta-cell function in adult offspring of women with diabetes in pregnancy
Kelstrup, L., Damm, Peter, Mathiesen, Elisabeth, Hansen, Torben, Vaag, Allan, Pedersen, Oluf Borbye & Clausen, Tine Dalsgaard, 24 Jun 2013, In: The Journal of clinical endocrinology and metabolism. 98, 9, p. 3793-3801 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Richness of human gut microbiome correlates with metabolic markers
Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J-M., Kennedy, S., Leonard, P., Li, J., Burgdorf, K. S., Grarup, N., Jørgensen, T., Brandslund, I., Nielsen, H. B., Juncker, A., dos Santos, M. B. Q., Levenez, F. & 62 others, , 2013, In: Nature. 500, 7464, p. 541-546 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes
Lohmueller, K. E., Sparsø, T. H., Li, Q., Galijatovic, E. A. A., Korneliussen, T. S., Albrechtsen, A., Banasik, K., Grarup, N., Hallgrimsdottir, I., Kiil, K., Oskari Kilpeläinen, T., Krarup, N. T., Pers, T. H., Sanchez, G., Hu, Y., DeGiorgio, M., Jørgensen, T., Sandbæk, A., Lauritzen, T., Brunak, S. & 6 others, , 5 Dec 2013, In: American Journal of Human Genetics. 93, 6, p. 1072-1086 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut microbiota may have influence on glucose and lipid metabolism.
Mikkelsen, K. H., Nielsen, M. F., Tvede, M., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 11 Nov 2013, In: Ugeskrift for Laeger. 175, 46, p. 2785-2788 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of GWAS identified BMI loci on changes in body weight among middle-aged danes during a five year period
Sandholt, C. H., Allin, K. H., Toft, U., Borglykke, A., Ribel-Madsen, R., Sparsø, T. H., Justesen, Johanne Marie, Harder, M. N., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 26 Jun 2013, In: Obesity. 22, 3, p. 901-908 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes
Snogdal, L. S., Grarup, Niels, Banasik, Karina, Wod, M., Jørgensen, T., Witte, D. R., Lauritzen, T., Nielsen, A. A., Brandslund, I., Christensen, C., Pedersen, Oluf Borbye, Yderstræde, K. B., Beck-Nielsen, H., Henriksen, J. E., Hansen, Torben & Højlund, K., 25 Oct 2013, In: BMC Medical Genetics. 14, 1, p. 113Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations in HNF1A result in marked alterations of plasma glycan profile
Thanabalasingham, G., Huffman, J. E., Kattla, J. J., Novokmet, M., Rudan, I., Gloyn, A. L., Hayward, C., Adamczyk, B., Reynolds, R. M., Muzinic, A., Hassanali, N., Pucic, M., Bennett, A. J., Essafi, A., Polasek, O., Mughal, S. A., Redzic, I., Primorac, D., Zgaga, L., Kolcic, I. & 20 others, , Apr 2013, In: Diabetes. 62, 4, p. 1329-37 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cohort Profile: The Health2006 cohort, Research Centre for Prevention and Health
Thuesen, B. H., Cerqueira, C., Aadahl, M., Ebstrup, J. F., Toft, U., Thyssen, J. P., Fenger, R. V., Hersoug, L., Elberling, Jesper Vraamark, Pedersen, Oluf Borbye, Hansen, Torben, Johansen, Jeanne Duus, Jørgensen, T. & Linneberg, Allan René, 24 Apr 2013, In: International Journal of Epidemiology. 43, 2, p. 568-575Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solute carrier family 2 member 1 is involved in the development of nonalcoholic fatty liver disease
Vazquez-Chantada, M., Gonzalez-Lahera, A., Martinez-Arranz, I., Garcia-Monzon, C., Regueiro, M. M., Garcia-Rodriguez, J. L., Schlangen, K. A., Mendibil, I., Rodriguez-Ezpeleta, N., Lozano, J. J., Banasik, K., Justesen, J. M., Jørgensen, T., Witte, D. R., Lauritzen, T., Hansen, T., Pedersen, O., Veyrie, N., Clement, K., Tordjman, J. & 12 others, , Feb 2013, In: Hepatology. 57, 2, p. 505-514 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes
Xie, W., Wood, A. R., Lyssenko, V., Weedon, M. N., Knowles, J. W., Alkayyali, S., Assimes, T. L., Quertermous, T., Abbasi, F., Paananen, J., Häring, H., Hansen, T., Pedersen, O., Smith, U., Laakso, M., Dekker, J. M., Nolan, J. J., Groop, L., Ferrannini, E., Adam, K-P. & 4 others, , Jun 2013, In: Diabetes. 62, 6, p. 2141-50 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mendelian Randomisation Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes
Yaghootkar, H., Lamina, C., Scott, R. A., Dastani, Z., Hivert, M-F., Warren, L. L., Stancáková, A., Buxbaum, S. G., Lyytikäinen, L-P., Henneman, P., Wu, Y., Cheung, C. Y., Pankow, J. S., Jackson, A. U., Gustafsson, S., Zhao, J. H., Ballantyne, C. M., Xie, W., Bergman, R. N., Boehnke, M. & 31 others, , 8 Jul 2013, In: Diabetes. 62, 10, p. 3589 3598 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
The frequent UCP2 -866G>A polymorphism protects against insulin resistance and is associated with obesity: a study of obesity and related metabolic traits among 17¿636 Danes
Andersen, G., Dalgaard, L. T., Justesen, Johanne Marie, Anthonsen, S., Nielsen, T., Thørner, L. W., Witte, D., Jørgensen, T., Clausen, J. O., Lauritzen, T., Holmkvist, J., Hansen, Torben & Pedersen, Oluf Borbye, 2012, In: International Journal of Obesity.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals
Banasik, Karina, Hollensted, M., Andersson, E., Sparsø, T., Sandbaek, A., Lauritzen, T., Jørgensen, T., Witte, D. R., Pedersen, Oluf Borbye & Hansen, Torben, 2012, In: B M C Medical Genetics. 13, p. 10Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variant SLC2A2 Is Associated with Risk of Cardiovascular Disease - Assessing the Individual and Cumulative Effect of 46 Type 2 Diabetes Related Genetic Variants
Borglykke, A., Grarup, Niels, Sparsø, T., Linneberg, Allan René, Fenger, M., Jeppesen, J., Hansen, Torben, Pedersen, Oluf Borbye & Jørgensen, T., 2012, In: P L o S One. 7, 11, p. e50418Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
Dastani, Z., Hivert, M-F., Timpson, N., Perry, J. R. B., Yuan, X., Scott, R. A., Henneman, P., Heid, I. M., Kizer, J. R., Lyytikäinen, L-P., Fuchsberger, C., Tanaka, T., Morris, A. P., Small, K., Isaacs, A., Beekman, M., Coassin, S., Lohman, K., Qi, L., Kanoni, S. & 31 others, , 2012, In: P L o S Genetics (Online). 8, 3, p. e1002607Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin and pancreatic hormone secretion in Caucasian non-diabetic carriers of the TCF7L2 rs7903146 risk T allele
Faerch, K., Pilgaard, K., Knop, Filip Krag, Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T. & Holst, Jens Juul, 2012, In: Diabetes, Obesity and Metabolism Online. 15, 1, p. 91-95 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
'Omics'-driven discoveries in prevention and treatment of type 2 diabetes
Gjesing, A. M. P. & Pedersen, Oluf Borbye, 2012, In: European Journal of Clinical Investigation. Supplement. 42, 6, p. 579-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fasting and oral glucose-stimulated levels of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are highly familial traits
Gjesing, A. M. P., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Urhammer, S. A., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Teis Schjals, 2012, In: Diabetologia. 55, 5, p. 1338-1345 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism
Helgadottir, A., Gretarsdottir, S., Thorleifsson, G., Holm, H., Patel, R. S., Gudnason, T., Jones, G. T., van Rij, A. M., Eapen, D. J., Baas, A. F., Tregouet, D-A., Morange, P-E., Emmerich, J., Lindblad, B., Gottsäter, A., Kiemeny, L. A., Lindholt, J. S., Sakalihasan, N., Ferrell, R. E., Carey, D. J. & 63 others, , 2012, In: Journal of the American College of Cardiology. 60, 8, p. 722-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Estimation of allele frequency and association mapping using next-generation sequencing data
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