- Published
Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1
Torekov, S. S., Ma, L., Grarup, N., Hartmann, B., Hainerová, I. A., Kielgast, U., Kissow, H., Rosenkilde, M., Lebl, J., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Madsen, O. D., Wang, J., Linneberg, A., Madsbad, S., Holst, J. J., Hansen, T., Pedersen, O. & 1 others, , 2011, In: Diabetologia. 54, 11, p. 2820-31 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine
Tobias, D. K., Merino, J., Ahmad, A., Aiken, C., Benham, J. L., Bodhini, D., Clark, A. L., Colclough, K., Corcoy, R., Cromer, S. J., Duan, D., Felton, J. L., Francis, E. C., Gillard, P., Gingras, V., Gaillard, R., Haider, E., Hughes, A., Ikle, J. M., Jacobsen, L. M. & 180 others, , 2023, In: Nature Medicine. 29, 10, p. 2438-2457 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A possible association between a dysfunctional skin barrier (filaggrin null-mutation status) and diabetes: a cross-sectional study
Thyssen, Jacob Pontoppidan, Linneberg, Allan René, Carlsen, B. C., Johansen, Jeanne Duus, Engkilde, K., Hansen, Torben, Pociot, Flemming, Pedersen, Oluf Borbye, Meldgaard, M., Szecsi, P. B., Stender, Steen & Menné, T., 1 Jan 2011, In: BMJ Open. 1, 1, p. e000062 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cohort Profile: The Health2006 cohort, Research Centre for Prevention and Health
Thuesen, B. H., Cerqueira, C., Aadahl, M., Ebstrup, J. F., Toft, U., Thyssen, J. P., Fenger, R. V., Hersoug, L., Elberling, Jesper Vraamark, Pedersen, Oluf Borbye, Hansen, Torben, Johansen, Jeanne Duus, Jørgensen, T. & Linneberg, Allan René, 24 Apr 2013, In: International Journal of Epidemiology. 43, 2, p. 568-575Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland
Thuesen, A. C. B., Stæger, F. F., Kaci, A., Solheim, M. H., Aukrust, I., Jørsboe, E., Santander, C. G., Andersen, M. K., Li, Z., Gilly, A., Stinson, S. E., Gjesing, A. P., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Grarup, N., Jørgensen, M. E., Zeggini, E., Bjørkhaug, L., Njølstad, P. R. & 3 others, , 2023, In: The Lancet Regional Health - Europe. 24, 12 p., 100529.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of pathogenic GCK variants in patients with common type 2 diabetes can lead to discontinuation of pharmacological treatment
Thuesen, Anne Cathrine Baun, Jensen, Rasmus Tanderup, Maagensen, H., Kristiansen, M. R., Sørensen, H. T., Vaag, Allan, Beck-Nielsen, H., Pedersen, Oluf Borbye, Grarup, Niels, Nielsen, J. S., Rungby, Jørgen, Gjesing, A. P., Storgaard, H., Vilsbøll, Tina & Hansen, Torben, 2023, In: Molecular Genetics and Metabolism Reports. 35, 8 p., 100972.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics of metabolic traits in Greenlanders
Thuesen, Anne Cathrine Baun, Lepola, Mette Andersen & Hansen, Torben, 2023, In: Danish Medical Journal. 70, 12, 9 p., A05230332.Research output: Contribution to journal › Review › Research › peer-review
- Published
Variants at the Interleukin 1 Gene Locus and Pericarditis
Thorolfsdottir, R. B., Jonsdottir, A. B., Sveinbjornsson, G., Aegisdottir, H. M., Oddsson, A., Stefansson, O. A., Halldorsson, G. H., Saevarsdottir, S., Thorleifsson, G., Stefansdottir, L., Pedersen, O. B., Sørensen, E., Ghouse, J., Raja, A. A., Zheng, C., Silajdzija, E., Rand, S. A., Erikstrup, C., Ullum, H., Mikkelsen, C. & 26 others, , 2024, In: JAMA Cardiology. 9, 2, p. 165-172 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations of the Inflammatory Marker YKL-40 with Measures of Obesity and Dyslipidaemia in Individuals at High Risk of Type 2 Diabetes
Thomsen, S. B., Gjesing, A. M. P., Rathcke, C. N., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Hansen, T., Pedersen, Oluf Borbye & drb459, drb459, 21 Jul 2015, In: PLOS ONE. 10, 7, p. 1-10 10 p., e0133672.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early life body size, growth and risks of systemic lupus erythematosus: A large Danish observational cohort study
Thomas, P. E., Jensen, B. W., Sørensen, K. K., Jacobsen, Søren, Aarestrup, J. & Baker, J. L., 2020, In: Seminars in Arthritis and Rheumatism. 50, 6, p. 1507-1512 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
The gut microbiota in multiple sclerosis varies with disease activity
Thirion, F., Sellebjerg, Finn Thorup, Fan, Yong, Lyu, Liwei, Hansen, T. H., Pons, N., Levenez, F., Quinquis, B., Stankevic, Evelina, Søndergaard, H. B., Dantoft, T. M., Poulsen, C. S., Forslund, S. K., drb459, drb459, Hansen, Torben, Brix, S., Oturai, A., Sørensen, Per Soelberg, Ehrlich, S. D. & Pedersen, Oluf Borbye, 2023, In: Genome Medicine. 15, 17 p., 1.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alteration of Gut Microbiome in Patients With Schizophrenia Indicates Links Between Bacterial Tyrosine Biosynthesis and Cognitive Dysfunction
Thirion, F., Speyer, H., Hansen, T. H., Nielsen, T., Fan, Y., Le Chatelier, E., Fromentin, S., Berland, M., Plaza Oñate, F., Pons, N., Galleron, N., Levenez, F., Markó, L., Birkner, T., Jørgensen, T., Forslund, S. K., Vestergaard, H., Hansen, T., Nordentoft, M., Mors, O. & 3 others, , 2023, In: Biological Psychiatry Global Open Science. 3, 2, p. 283-291 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sphingolipids Are Depleted in Alcohol-Related Liver Fibrosis
Thiele, M., Suvitaival, T., Trošt, K., Kim, M., de Zawadzki, A., Kjaergaard, M., Rasmussen, D. N., Lindvig, K. P., Israelsen, M., Detlefsen, S., Andersen, P., Juel, H. B., Nielsen, T., Georgiou, S., Filippa, V., Kuhn, M., Nishijima, S., Moitinho-Silva, L., Rossing, P., Trebicka, J. & 14 others, , 2023, In: Gastroenterology. 164, 7, p. 1248-1260Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Opportunities and barriers in omics-based biomarker discovery for steatotic liver diseases
Thiele, M., Villesen, I. F., Niu, L., Johansen, S., Sulek, K., Nishijima, S., Espen, L. V., Keller, M., Israelsen, M., Suvitaival, T., Zawadzki, A. D., Juel, H. B., Brol, M. J., Stinson, S. E., Huang, Y., Silva, M. C. A., Kuhn, M., Anastasiadou, E., Leeming, D. J., Karsdal, M. & 12 others, , 2024, (E-pub ahead of print) In: Journal of Hepatology.Research output: Contribution to journal › Review › Research › peer-review
- Published
FGL1 as a modulator of plasma D-dimer levels: exome-wide marker analysis of plasma tPA, PAI-1 and D-dimer
Thibord, F., Song, C., Pattee, J., Rodriguez, B. A. T., Chen, M-H., O'Donnell, C. J., Kleber, M. E., Delgado, G. E., Guo, X., Yao, J., Taylor, K. D., Ozel, A. B., Brody, J. A., McKnight, B., Gyorgy, B., Simonsick, E., Leonard, H. L., Carrasquilla, G. D., Guindo-Martinez, M., Silveira, A. & 30 others, , 2021, In: Journal of Thrombosis and Haemostasis. 19, 8, p. 2019-2028Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations in HNF1A result in marked alterations of plasma glycan profile
Thanabalasingham, G., Huffman, J. E., Kattla, J. J., Novokmet, M., Rudan, I., Gloyn, A. L., Hayward, C., Adamczyk, B., Reynolds, R. M., Muzinic, A., Hassanali, N., Pucic, M., Bennett, A. J., Essafi, A., Polasek, O., Mughal, S. A., Redzic, I., Primorac, D., Zgaga, L., Kolcic, I. & 20 others, , Apr 2013, In: Diabetes. 62, 4, p. 1329-37 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DeepFake electrocardiograms using generative adversarial networks are the beginning of the end for privacy issues in medicine
Thambawita, Vajira Lasantha Bandara, Isaksen, Jonas L., Hicks, S. A., Ghouse, Jonas, Ahlberg, G., Linneberg, Allan René, Grarup, Niels, Ellervik, Christina, Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., Holstein-Rathlou, N., Strümke, I., Hammer, H. L., Maleckar, M. M., Halvorsen, P., Riegler, M. A. & Kanters, Jørgen K., 2021, In: Scientific Reports. 11, 1, 8 p., 21896.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DeepFake electrocardiograms: the key for open science for artificial intelligence in medicine
Thambawita, V., Isaksen, Jonas L., Hicks, S. A., Ghouse, Jonas, Ahlberg, Gustav, Linneberg, Allan René, Grarup, Niels, Ellervik, Christina, Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., Holstein-Rathlou, N., Strümke, I., Hammer, H. L., Maleckar, M., Halvorsen, P., Riegler, M. A. & Kanters, Jørgen K., 2022, 17 p. (medRxiv).Research output: Working paper › Preprint
- Published
Interethnic analyses of blood pressure loci in populations of East Asian and European descent
The International Genomics of Blood Pressure (iGEN-BP) Consortium, T. I. G. O. B. P. (. C., 2018, In: Nature Communications. 9, 5052.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An adiposity force induces obesity in humans independently of a normal energy balance system-a thought experiment
Sørensen, Thorkild I.A., 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 9 p., 20220203.Research output: Contribution to journal › Review › Research › peer-review
- Published
Do gene-environment interactions have implications for the precision prevention of type 2 diabetes?
Sørensen, Thorkild I.A., Metz, Sophia & Kilpeläinen, Tuomas O., 2022, In: Diabetologia. 65, p. 1804–1813 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Sequencing and de novo assembly of 150 genomes from Denmark as a population reference
Sørensen, L. M., Jensen, J. M., Petersen, B., Sibbesen, J. A., Liu, S., Villesen, P., Skov, L., Belling, K. G., Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R., Ye, W., Rao, J., Guo, X. & 39 others, , 2017, In: Nature. 548, 7665, p. 87-91 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Early life body size and its associations with adult bladder cancer
Sørensen, K. K., Jensen, B. W., Thomas, P. E., Madsen, K., Eriksson, Frank, Aarestrup, J. & Baker, J. L., 2020, In: Annals of Human Biology. 47, 2, p. 166-172 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of smoking on the urinary excretion of 8-oxodG and 8-oxoGuo in patients with type 2 diabetes
Sørensen, A., Kjær, L. K., Petersen, K. M., Henriksen, T., Cejvanovic, V., Pedersen, Oluf Borbye, Hansen, Torben, Christensen, C. K., Brandslund, I. & Poulsen, Henrik Enghusen, 2017, In: Scandinavian Journal of Clinical & Laboratory Investigation. 77, 4, p. 253-258 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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