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Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts
Atabaki-Pasdar, N., Ohlsson, M., Viñuela, A., Frau, F., Pomares-Millan, H., Haid, M., Jones, A. G., Thomas, E. L., Koivula, R. W., Kurbasic, A., Mutie, P. M., Fitipaldi, H., Fernandez, J., Dawed, A. Y., Giordano, G. N., Forgie, I. M., McDonald, T. J., Rutters, F., Cederberg, H., Chabanova, E. & 30 others, , 2020, In: PLoS Medicine. 17, 6, 27 p., e1003149.Research output: Contribution to journal › Journal article › Research › peer-review
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Precision subclassification of type 2 diabetes: a systematic review
Misra, S., Wagner, R., Ozkan, B., Schön, M., Sevilla-Gonzalez, M., Prystupa, K., Wang, C. C., Kreienkamp, R. J., Cromer, S. J., Rooney, M. R., Duan, D., Thuesen, A. C. B., Wallace, A. S., Leong, A., Deutsch, A. J., Andersen, M. K., Billings, L. K., Eckel, R. H., Sheu, W. H-H., Hansen, T. & 8 others, , 2023, In: Communications Medicine. 3, 19 p., 138.Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young
Østoft, S. H., Bagger, J. I., Hansen, Torben, Hartmann, Bolette, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 1 Aug 2015, In: European Journal of Endocrinology. 173, 2, p. 205-215 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Post-load glucose subgroups and associated metabolic traits in individuals with type 2 diabetes: An IMI-DIRECT study
Obura, M., Beulens, J. W. J., Slieker, R., Koopman, A. D. M., Hoekstra, T., Nijpels, G., Elders, P., Koivula, R. W., Kurbasic, A., Laakso, M., Hansen, T. H., Ridderstråle, M., Hansen, T., Pavo, I., Forgie, I., Jablonka, B., Ruetten, H., Mari, A., McCarthy, M. I., Walker, M. & 19 others, , 2020, In: PLoS ONE. 15, 11, 11 p., e0242360.Research output: Contribution to journal › Journal article › Research › peer-review
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Possible prediction of obesity-related liver disease in children and adolescents using indices of body composition
Johansen, M. J., Lund, Morten Asp Vonsild, Ängquist, Lars, Fonvig, Cilius Esmann, Holm, L. A., Chabanova, E., Thomsen, Henrik S., Hansen, Torben & Holm, Jens-Christian, 2022, In: Pediatric Obesity. 17, 10, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Population-based studies of relationships between dietary acidity load, insulin resistance and incident diabetes in Danes 11 Medical and Health Sciences 1103 Clinical Sciences
Gæde, J., Nielsen, T., Madsen, M. L., Toft, Ulla Marie Nørgaard, Jørgensen, T., Overvad, K., Tjønneland, Anne, Hansen, Torben, Allin, K. H. & Pedersen, Oluf Borbye, 6 Oct 2018, In: Nutrition Journal. 17, 1, 91.Research output: Contribution to journal › Journal article › Research › peer-review
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Population-based pediatric reference values for serum parathyroid hormone, vitamin D, calcium, and phosphate in Danish/North-European white children and adolescents
Vissing Landgrebe, A., Lund, Morten Asp Vonsild, Lausten-Thomsen, U., Frithioff-Bøjsøe, C., Fonvig, Cilius Esmann, Lind Plesner, J., Aas Holm, L., Jespersen, Thomas, Hansen, Torben & Holm, Jens-Christian, 2021, In: Clinica Chimica Acta. 523, p. 483-490Research output: Contribution to journal › Journal article › Research › peer-review
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Population genomics of the Viking world: [incl. correction]
Margaryan, A., Lawson, D. J., Sikora, M., Racimo, F., Rasmussen, S., Moltke, I., Cassidy, L. M., Jørsboe, E., Ingason, A., Pedersen, M. W., Korneliussen, T., Wilhelmson, H., Buś, M. M., de Barros Damgaard, P., Martiniano, R., Renaud, G., Bhérer, C., Moreno-Mayar, J. V., Fotakis, A. K., Allen, M. & 30 others, , 2020, In: Nature. 585, 7825, p. 390-396 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ponderal index at birth associates with later risk of gestational diabetes mellitus
Crusell, Mie Korslund Wiinblad, Damm, Peter, Hansen, Torben, Pedersen, Oluf Borbye, Glümer, C., Vaag, Allan & Lauenborg, J., Aug 2017, In: Archives of Gynecology and Obstetrics. 296, 2, p. 249-256 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polygenic predisposition to breast cancer and the risk of coronary artery disease
D'Souza, M., Schou, Morten, Skals, R., Weeke, P. E., Lee, C., Smedegaard, L., Madelaire, C., Gerds, Thomas Alexander, Poulsen, Henrik Enghusen, Hansen, Torben, Grarup, Niels, Pedersen, Oluf Borbye, Stender, Steen, Engstrøm, Thomas, Fosbøl, E., Nielsen, D., Gislason, Gunnar Hilmar, Køber, Lars Valeur, Torp-Pedersen, C. & Andersson, C., 2019, In: International Journal of Cardiology. 291, p. 145-151 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
Okbay, A., Wu, Y., Wang, N., Jayashankar, H., Bennett, M., Nehzati, S. M., Sidorenko, J., Kweon, H., Goldman, G., Gjorgjieva, T., Jiang, Y., Hicks, B., Tian, C., Hinds, D. A., Ahlskog, R., Magnusson, P. K. E., Oskarsson, S., Hayward, C., Campbell, A., Porteous, D. J. & 31 others, , 2022, In: Nature Genetics. 54, 4, p. 437-449 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pleiotropic genes for metabolic syndrome and inflammation
Kraja, A. T., Chasman, D. I., North, K. E., Reiner, A. P., Yanek, L. R., Oskari Kilpeläinen, T., Smith, J. A., Dehghan, A., Dupuis, J., Johnson, A. D., Feitosa, M. F., Tekola-Ayele, F., Chu, A. Y., Nolte, I. M., Dastani, Z., Morris, A., Pendergrass, S. A., Sun, Y. V., Ritchie, M. D., Vaez, A. & 31 others, , 2014, In: Molecular Genetics and Metabolism. 112, 4, p. 317-38 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma alkylresorcinols reflect gluten intake and distinguish between gluten-rich and gluten-poor diets in a population at risk of metabolic syndrome
Lind, M. V., Madsen, M. L., Rumessen, J. J., drb459, drb459, Gøbel, R. J., Hansen, Torben, Lauritzen, Lotte, Pedersen, Oluf Borbye, Kristensen, M. B. & Ross, A. B., 2016, In: Journal of Nutrition. 146, 10, p. 1991-1998 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physiology insights
Watanabe, R. M. & Hansen, Torben, 2016, The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation. Springer, p. 207-221 15 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Physiologic characterization of type 2 diabetes-related loci
Grarup, Niels, Sparsø, T. & Hansen, Torben, 1 Dec 2010, In: Current Diabetes Reports. 10, 6, p. 485-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers
Schnurr, T. M., Jørsboe, E., Chadt, A., Dahl-Petersen, I. K., Kristensen, Jonas Møller, Wojtaszewski, Jørgen F P, Springer, C., Bjerregaard, P., Brage, S., Pedersen, Oluf Borbye, Moltke, Ida, Grarup, Niels, Al-Hasani, H., Albrechtsen, Anders, Jørgensen, M. E. & Hansen, Torben, 2021, In: Diabetologia. 64, p. 1795-1804Research output: Contribution to journal › Journal article › Research › peer-review
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Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity
Lepola, Mette Andersen, Ängquist, Lars, Bork-Jensen, J., Jonsson, Anna Elisabet, Stinson, Sara, Sandholt, C. H., Thodberg, Malte, Pikkupeura, Laura Maarit, Ongstad, E. L., Grarup, Niels, Astrup, A., Pedersen, Oluf Borbye, Williams, K., Barrès, Romain, Sørensen, Thorkild I.A., Linneberg, Allan René, Grimsby, J., Rhodes, C. J. & Hansen, Torben, 2023, In: Diabetes Care. 46, 5, p. 985–992 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children
Oskari Kilpeläinen, T., Qi, L., Brage, S., Sharp, S. J., Sonestedt, E., Demerath, E., Ahmad, T., Mora, S., Kaakinen, M., Sandholt, C. H., Holzapfel, C., Autenrieth, C. S., Hyppönen, E., Cauchi, S., He, M., Kutalik, Z., Kumari, M., Stancáková, A., Meidtner, K., Balkau, B. & 96 others, , 1 Nov 2011, In: P L o S Medicine (Online). 8, 11, p. e1001116Research output: Contribution to journal › Journal article › Research › peer-review
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Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
Schmidt, A. F., Holmes, M. V., Preiss, D., Swerdlow, D. I., Denaxas, S., Fatemifar, G., Faraway, R., Finan, C., Valentine, D., Fairhurst-Hunter, Z., Hartwig, F. P., Horta, B. L., Hypponen, E., Power, C., Moldovan, M., Van Iperen, E., Hovingh, K., Demuth, I., Norman, K., Steinhagen-Thiessen, E. & 145 others, , 2019, In: BMC Cardiovascular Disorders. 19, 1, 10 p., 240.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacogenetics and individual responses to treatment of hyperglycemia in type 2 diabetes.
pjx571, pjx571, Galijatovic, E. A. A., Roepstorff, S., Hansen, Torben & drb459, drb459, Oct 2015, In: Pharmacogenetics and Genomics. 25, 10, p. 475-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pediatric Features of Genetic Predisposition to Polycystic Ovary Syndrome
Zhu, J., Eliasen, A. U., Aris, I. M., Stinson, Sara, Holm, Jens-Christian, Hansen, Torben, Hivert, M., Bønnelykke, Klaus, Salem, R. M., Hirschhorn, J. N. & Chan, Y., 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 2, p. 380-388Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with Obesity Caused by Melanocortin-4 Receptor Mutations Can Be Treated with a Glucagon-like Peptide-1 Receptor Agonist
Iepsen, E. W., Zhang, J., Thomsen, Henrik S., Hansen, E. L., Hollensted, M., Madsbad, Sten, Hansen, Torben, Holst, Jens Juul, Holm, Jens-Christian & Torekov, Signe Sørensen, 2018, In: Cell Metabolism. 28, 1, p. 23-32.e3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia
Hyltén-Cavallius, L., Iepsen, E. W., Albrechtsen, Nicolai Jacob Wewer, Svendstrup, M., Lubberding, Anniek Frederike, Hartmann, Bolette, Jespersen, Thomas, Linneberg, Allan René, Christiansen, M., drb459, drb459, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K., Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Circulation. 135, 18, p. 1705-1719 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patient profiling for success after weight loss surgery (GO Bypass study): An interdisciplinary study protocol
Christensen, Bodil Just, Schmidt, J. B., Nielsen, M. S., Tækker, L., Holm, Lotte, Lunn, Susanne, Bredie, Wender, Ritz, C., Holst, Jens Juul, Hansen, Torben, Hilbert, A., le Roux, C. W., Hulme, O. J., Siebner, Hartwig Roman, Morville, T., Naver, L., Floyd, A. K. & Sjödin, Anders Mikael, 2018, In: Contemporary Clinical Trials Communications. 10, p. 121-130 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathophysiological-based treatments of complications of cirrhosis
Møller, Søren, Kimer, N., Barløse, Mads Christian Johannes & Bendtsen, Flemming, 2020, In: Scandinavian Journal of Gastroenterology. 55, 4, p. 383-394Research output: Contribution to journal › Review › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Estimation of allele frequency and association mapping using next-generation sequencing data
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