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  1. Published

    Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts

    Atabaki-Pasdar, N., Ohlsson, M., Viñuela, A., Frau, F., Pomares-Millan, H., Haid, M., Jones, A. G., Thomas, E. L., Koivula, R. W., Kurbasic, A., Mutie, P. M., Fitipaldi, H., Fernandez, J., Dawed, A. Y., Giordano, G. N., Forgie, I. M., McDonald, T. J., Rutters, F., Cederberg, H., Chabanova, E. & 30 others, Dale, M., Masi, F. D., Thomas, C. E., Allin, K. H., Hansen, T. H., Heggie, A., Hong, M., Elders, P. J. M., Kennedy, G., Kokkola, T., Pedersen, H. K., Mahajan, A., McEvoy, D., Pattou, F., Raverdy, V., Häussler, R. S., Sharma, S., Thomsen, Henrik S., Vangipurapu, J., Vestergaard, H., Adamski, J., Musholt, P. B., Brage, S., Brunak, Søren, Dermitzakis, E., Frost, G., Hansen, Torben, Laakso, M., Pedersen, Oluf Borbye & IMI-DIRECT consortium, I. C., 2020, In: PLoS Medicine. 17, 6, 27 p., e1003149.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Precision subclassification of type 2 diabetes: a systematic review

    Misra, S., Wagner, R., Ozkan, B., Schön, M., Sevilla-Gonzalez, M., Prystupa, K., Wang, C. C., Kreienkamp, R. J., Cromer, S. J., Rooney, M. R., Duan, D., Thuesen, A. C. B., Wallace, A. S., Leong, A., Deutsch, A. J., Andersen, M. K., Billings, L. K., Eckel, R. H., Sheu, W. H-H., Hansen, T. & 8 others, Stefan, N., Goodarzi, M. O., Ray, D., Selvin, E., Florez, J. C., Meigs, J. B., Udler, M. S. & ADA/EASD PMDI, A. P., 2023, In: Communications Medicine. 3, 19 p., 138.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young

    Østoft, S. H., Bagger, J. I., Hansen, Torben, Hartmann, Bolette, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 1 Aug 2015, In: European Journal of Endocrinology. 173, 2, p. 205-215 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Post-load glucose subgroups and associated metabolic traits in individuals with type 2 diabetes: An IMI-DIRECT study

    Obura, M., Beulens, J. W. J., Slieker, R., Koopman, A. D. M., Hoekstra, T., Nijpels, G., Elders, P., Koivula, R. W., Kurbasic, A., Laakso, M., Hansen, T. H., Ridderstråle, M., Hansen, T., Pavo, I., Forgie, I., Jablonka, B., Ruetten, H., Mari, A., McCarthy, M. I., Walker, M. & 19 others, Heggie, A., McDonald, T. J., Perry, M. H., De Masi, F., Brunak, Søren, Mahajan, A., Giordano, G. N., Kokkola, T., Dermitzakis, E., Viñuela, A., Pedersen, Oluf Borbye, Schwenk, J. M., Adamski, J., Teare, H. J. A., Pearson, E. R., Franks, P. W., Hart, L. M. T., Rutters, F. & for the IMI-DIRECT Consortium, F. T. I. C., 2020, In: PLoS ONE. 15, 11, 11 p., e0242360.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Possible prediction of obesity-related liver disease in children and adolescents using indices of body composition

    Johansen, M. J., Lund, Morten Asp Vonsild, Ängquist, Lars, Fonvig, Cilius Esmann, Holm, L. A., Chabanova, E., Thomsen, Henrik S., Hansen, Torben & Holm, Jens-Christian, 2022, In: Pediatric Obesity. 17, 10, 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Population-based studies of relationships between dietary acidity load, insulin resistance and incident diabetes in Danes 11 Medical and Health Sciences 1103 Clinical Sciences

    Gæde, J., Nielsen, T., Madsen, M. L., Toft, Ulla Marie Nørgaard, Jørgensen, T., Overvad, K., Tjønneland, Anne, Hansen, Torben, Allin, K. H. & Pedersen, Oluf Borbye, 6 Oct 2018, In: Nutrition Journal. 17, 1, 91.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Population-based pediatric reference values for serum parathyroid hormone, vitamin D, calcium, and phosphate in Danish/North-European white children and adolescents

    Vissing Landgrebe, A., Lund, Morten Asp Vonsild, Lausten-Thomsen, U., Frithioff-Bøjsøe, C., Fonvig, Cilius Esmann, Lind Plesner, J., Aas Holm, L., Jespersen, Thomas, Hansen, Torben & Holm, Jens-Christian, 2021, In: Clinica Chimica Acta. 523, p. 483-490

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Population genomics of the Viking world: [incl. correction]

    Margaryan, A., Lawson, D. J., Sikora, M., Racimo, F., Rasmussen, S., Moltke, I., Cassidy, L. M., Jørsboe, E., Ingason, A., Pedersen, M. W., Korneliussen, T., Wilhelmson, H., Buś, M. M., de Barros Damgaard, P., Martiniano, R., Renaud, G., Bhérer, C., Moreno-Mayar, J. V., Fotakis, A. K., Allen, M. & 30 others, Allmäe, R., Molak, M., Cappellini, Enrico, Scorrano, Gabriele, McColl, Hugh, Buzhilova, A., Fox, A., Albrechtsen, Anders, Schütz, B., Skar, B., Arcini, C., Lundstrøm, I., Cheng, J., Stenderup, Jesper Tandberg, Iversen, K. H., Arge, S. V., Ellingvåg, S., Orlando, L., Pentz, P., Jessen, M. D., Pedersen, A., Jørkov, M L S, Lynnerup, Niels, Gilbert, M Thomas P, Allentoft, Morten Erik, Sindbæk, S. M., Kristiansen, K., Nielsen, Rasmus, Werge, Thomas & Willerslev, Eske, 2020, In: Nature. 585, 7825, p. 390-396 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Ponderal index at birth associates with later risk of gestational diabetes mellitus

    Crusell, Mie Korslund Wiinblad, Damm, Peter, Hansen, Torben, Pedersen, Oluf Borbye, Glümer, C., Vaag, Allan & Lauenborg, J., Aug 2017, In: Archives of Gynecology and Obstetrics. 296, 2, p. 249-256 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Polygenic predisposition to breast cancer and the risk of coronary artery disease

    D'Souza, M., Schou, Morten, Skals, R., Weeke, P. E., Lee, C., Smedegaard, L., Madelaire, C., Gerds, Thomas Alexander, Poulsen, Henrik Enghusen, Hansen, Torben, Grarup, Niels, Pedersen, Oluf Borbye, Stender, Steen, Engstrøm, Thomas, Fosbøl, E., Nielsen, D., Gislason, Gunnar Hilmar, Køber, Lars Valeur, Torp-Pedersen, C. & Andersson, C., 2019, In: International Journal of Cardiology. 291, p. 145-151 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

    Okbay, A., Wu, Y., Wang, N., Jayashankar, H., Bennett, M., Nehzati, S. M., Sidorenko, J., Kweon, H., Goldman, G., Gjorgjieva, T., Jiang, Y., Hicks, B., Tian, C., Hinds, D. A., Ahlskog, R., Magnusson, P. K. E., Oskarsson, S., Hayward, C., Campbell, A., Porteous, D. J. & 31 others, Freese, J., Herd, P., Agee, M., Alipanahi, B., Auton, A., Bell, R. K., Bryc, K., Elson, S. L., Fontanillas, P., Furlotte, N. A., Hinds, D. A., Huber, K. E., Kleinman, A., Litterman, N. K., McCreight, J. C., McIntyre, M. H., Mountain, J. L., Northover, C. A. M., Pitts, S. J., Sathirapongsasuti, J. F., Sazonova, O. V., Shelton, J. F., Pers, Tune H, Timshel, P., Ahluwalia, Tarun Veer Singh, Bønnelykke, Klaus, Bisgaard, H., Sørensen, Thorkild I.A., 23andMe Research Team, 2. R. T., Social Science Genetic Association Consortium, S. S. G. A. C. & LifeLines Cohort Study, L. C. S., 2022, In: Nature Genetics. 54, 4, p. 437-449 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Pleiotropic genes for metabolic syndrome and inflammation

    Kraja, A. T., Chasman, D. I., North, K. E., Reiner, A. P., Yanek, L. R., Oskari Kilpeläinen, T., Smith, J. A., Dehghan, A., Dupuis, J., Johnson, A. D., Feitosa, M. F., Tekola-Ayele, F., Chu, A. Y., Nolte, I. M., Dastani, Z., Morris, A., Pendergrass, S. A., Sun, Y. V., Ritchie, M. D., Vaez, A. & 31 others, Lin, H., Ligthart, S., Marullo, L., Rohde, R., Shao, Y., Ziegler, M. A., Im, H. K., Schnabel, R. B., Jørgensen, T., Jørgensen, M. E., Hansen, Torben, Pedersen, Oluf Borbye, Stolk, R. P., Snieder, H., Hofman, A., Uitterlinden, A. G., Franco, O. H., Ikram, M. A., Richards, J. B., Rotimi, C., Wilson, J. G., Lange, L., Ganesh, S. K., Nalls, M., Rasmussen-Torvik, L. J., Pankow, J. S., Coresh, J., Tang, W., Linda Kao, W. H., Boerwinkle, E. & Cross Consortia Pleiotropy (XC-Pleiotropy) Group, C. C. P. (. G., 2014, In: Molecular Genetics and Metabolism. 112, 4, p. 317-38 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Plasma alkylresorcinols reflect gluten intake and distinguish between gluten-rich and gluten-poor diets in a population at risk of metabolic syndrome

    Lind, M. V., Madsen, M. L., Rumessen, J. J., drb459, drb459, Gøbel, R. J., Hansen, Torben, Lauritzen, Lotte, Pedersen, Oluf Borbye, Kristensen, M. B. & Ross, A. B., 2016, In: Journal of Nutrition. 146, 10, p. 1991-1998 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Physiology insights

    Watanabe, R. M. & Hansen, Torben, 2016, The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation. Springer, p. 207-221 15 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  15. Published

    Physiologic characterization of type 2 diabetes-related loci

    Grarup, Niels, Sparsø, T. & Hansen, Torben, 1 Dec 2010, In: Current Diabetes Reports. 10, 6, p. 485-97 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers

    Schnurr, T. M., Jørsboe, E., Chadt, A., Dahl-Petersen, I. K., Kristensen, Jonas Møller, Wojtaszewski, Jørgen F P, Springer, C., Bjerregaard, P., Brage, S., Pedersen, Oluf Borbye, Moltke, Ida, Grarup, Niels, Al-Hasani, H., Albrechtsen, Anders, Jørgensen, M. E. & Hansen, Torben, 2021, In: Diabetologia. 64, p. 1795-1804

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity

    Lepola, Mette Andersen, Ängquist, Lars, Bork-Jensen, J., Jonsson, Anna Elisabet, Stinson, Sara, Sandholt, C. H., Thodberg, Malte, Pikkupeura, Laura Maarit, Ongstad, E. L., Grarup, Niels, Astrup, A., Pedersen, Oluf Borbye, Williams, K., Barrès, Romain, Sørensen, Thorkild I.A., Linneberg, Allan René, Grimsby, J., Rhodes, C. J. & Hansen, Torben, 2023, In: Diabetes Care. 46, 5, p. 985–992 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children

    Oskari Kilpeläinen, T., Qi, L., Brage, S., Sharp, S. J., Sonestedt, E., Demerath, E., Ahmad, T., Mora, S., Kaakinen, M., Sandholt, C. H., Holzapfel, C., Autenrieth, C. S., Hyppönen, E., Cauchi, S., He, M., Kutalik, Z., Kumari, M., Stancáková, A., Meidtner, K., Balkau, B. & 96 others, Tan, J. T., Mangino, M., Timpson, N. J., Song, Y., Zillikens, M. C., Jablonski, K. A., Garcia, M. E., Johansson, S., Bragg-Gresham, J. L., Wu, Y., van Vliet-Ostaptchouk, J. V., Onland-Moret, N. C., Zimmermann, E., Rivera, N. V., Tanaka, T., Stringham, H. M., Silbernagel, G., Kanoni, S., Feitosa, M. F., Snitker, S., Ruiz, J. R., Metter, J., Larrad, M. T. M., Atalay, M., Hakanen, M., Amin, N., Cavalcanti-Proença, C., Grøntved, A., Hallmans, G., Jansson, J., Kuusisto, J., Kähönen, M., Lutsey, P. L., Nolan, J. J., Palla, L., Pedersen, Oluf Borbye, Pérusse, L., Renström, F., Scott, R. A., Shungin, D., Sovio, U., Tammelin, T. H., Rönnemaa, T., Lakka, T. A., Uusitupa, M., Rios, M. S., Ferrucci, L., Bouchard, C., Meirhaeghe, A., Fu, M., Walker, M., Borecki, I. B., Dedoussis, G. V., Fritsche, A., Ohlsson, C., Boehnke, M., Bandinelli, S., van Duijn, C. M., Ebrahim, S., Lawlor, D. A., Gudnason, V., Harris, T. B., Sørensen, Thorkild I.A., Mohlke, K. L., Hofman, A., Uitterlinden, A. G., Tuomilehto, J., Lehtimäki, T., Raitakari, O., Isomaa, B., Njølstad, P. R., Florez, J. C., Liu, S., Ness, A., Spector, T. D., Tai, E. S., Froguel, P., Boeing, H., Laakso, M., Marmot, M., Bergmann, S., Power, C., Khaw, K., Chasman, D., Ridker, P., Hansen, Torben, Monda, K. L., Illig, T., Järvelin, M., Wareham, N. J., Hu, F. B., Groop, L. C., Orho-Melander, M., Ekelund, U., Franks, P. W. & Loos, R. J. F., 1 Nov 2011, In: P L o S Medicine (Online). 8, 11, p. e1001116

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

    Schmidt, A. F., Holmes, M. V., Preiss, D., Swerdlow, D. I., Denaxas, S., Fatemifar, G., Faraway, R., Finan, C., Valentine, D., Fairhurst-Hunter, Z., Hartwig, F. P., Horta, B. L., Hypponen, E., Power, C., Moldovan, M., Van Iperen, E., Hovingh, K., Demuth, I., Norman, K., Steinhagen-Thiessen, E. & 145 others, Demuth, J., Bertram, L., Lill, C. M., Coassin, S., Willeit, J., Kiechl, S., Willeit, K., Mason, D., Wright, J., Morris, R., Wanamethee, G., Whincup, P., Ben-Shlomo, Y., McLachlan, S., Price, J. F., Kivimaki, M., Welch, C., Sanchez-Galvez, A., Marques-Vidal, P., Nicolaides, A., Panayiotou, A. G., Onland-Moret, N. C., Van Der Schouw, Y. T., Matullo, G., Fiorito, G., Guarrera, S., Sacerdote, C., Wareham, N. J., Langenberg, C., Scott, R. A., Luan, J., Bobak, M., Malyutina, S., Pajak, A., Kubinova, R., Tamosiunas, A., Pikhart, H., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Jess, T., Cooper, J., Humphries, S. E., Brilliant, M., Kitchner, T., Hakonarson, H., Carrell, D. S., McCarty, C. A., Lester, K. H., Larson, E. B., Crosslin, D. R., De Andrade, M., Roden, D. M., Denny, J. C., Carty, C., Hancock, S., Attia, J., Holliday, E., Scott, R., Schofield, P., O'Donnell, M., Yusuf, S., Chong, M., Pare, G., Van Der Harst, P., Said, M. A., Eppinga, R. N., Verweij, N., Snieder, H., Christen, T., Mook-Kanamori, D. O., Gustafsson, S., Lind, L., Ingelsson, E., Pazoki, R., Franco, O., Hofman, A., Uitterlinden, A., Dehghan, A., Teumer, A., Baumeister, S., Dörr, M., Lerch, M. M., Völker, U., Völzke, H., Ward, J., Pell, J. P., Meade, T., Christophersen, I. E., Maitland-Van Der Zee, A. H., Baranova, E. V., Young, R., Ford, I., Campbell, A., Padmanabhan, S., Bots, M. L., Grobbee, D. E., Froguel, P., Thuillier, D., Roussel, R., Bonnefond, A., Cariou, B., Smart, M., Bao, Y., Kumari, M., Mahajan, A., Hopewell, J. C., Seshadri, S., Dale, C., Costa, R. P. E., Ridker, P. M., Chasman, D. I., Reiner, A. P., Ritchie, M. D., Lange, L. A., Cornish, A. J., Dobbins, S. E., Hemminki, K., Kinnersley, B., Sanson, M., Labreche, K., Simon, M., Bondy, M., Law, P., Speedy, H., Allan, J., Li, N., Went, M., Weinhold, N., Morgan, G., Sonneveld, P., Nilsson, B., Goldschmidt, H., Sud, A., Engert, A., Hansson, M., Hemingway, H., Asselbergs, F. W., Patel, R. S., Keating, B. J., Sattar, N., Houlston, R., Casas, J. P. & Hingorani, A. D., 2019, In: BMC Cardiovascular Disorders. 19, 1, 10 p., 240.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Pharmacogenetics and individual responses to treatment of hyperglycemia in type 2 diabetes.

    pjx571, pjx571, Galijatovic, E. A. A., Roepstorff, S., Hansen, Torben & drb459, drb459, Oct 2015, In: Pharmacogenetics and Genomics. 25, 10, p. 475-84 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Pediatric Features of Genetic Predisposition to Polycystic Ovary Syndrome

    Zhu, J., Eliasen, A. U., Aris, I. M., Stinson, Sara, Holm, Jens-Christian, Hansen, Torben, Hivert, M., Bønnelykke, Klaus, Salem, R. M., Hirschhorn, J. N. & Chan, Y., 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 2, p. 380-388

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Patients with Obesity Caused by Melanocortin-4 Receptor Mutations Can Be Treated with a Glucagon-like Peptide-1 Receptor Agonist

    Iepsen, E. W., Zhang, J., Thomsen, Henrik S., Hansen, E. L., Hollensted, M., Madsbad, Sten, Hansen, Torben, Holst, Jens Juul, Holm, Jens-Christian & Torekov, Signe Sørensen, 2018, In: Cell Metabolism. 28, 1, p. 23-32.e3

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia

    Hyltén-Cavallius, L., Iepsen, E. W., Albrechtsen, Nicolai Jacob Wewer, Svendstrup, M., Lubberding, Anniek Frederike, Hartmann, Bolette, Jespersen, Thomas, Linneberg, Allan René, Christiansen, M., drb459, drb459, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K., Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Circulation. 135, 18, p. 1705-1719 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Patient profiling for success after weight loss surgery (GO Bypass study): An interdisciplinary study protocol

    Christensen, Bodil Just, Schmidt, J. B., Nielsen, M. S., Tækker, L., Holm, Lotte, Lunn, Susanne, Bredie, Wender, Ritz, C., Holst, Jens Juul, Hansen, Torben, Hilbert, A., le Roux, C. W., Hulme, O. J., Siebner, Hartwig Roman, Morville, T., Naver, L., Floyd, A. K. & Sjödin, Anders Mikael, 2018, In: Contemporary Clinical Trials Communications. 10, p. 121-130 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Pathophysiological-based treatments of complications of cirrhosis

    Møller, Søren, Kimer, N., Barløse, Mads Christian Johannes & Bendtsen, Flemming, 2020, In: Scandinavian Journal of Gastroenterology. 55, 4, p. 383-394

    Research output: Contribution to journal › Review › Research › peer-review

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