- Published
A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes
Moltke, I., Grarup, N., Jørgensen, M. E., Bjerregaard, P., Treebak, J. T., Fumagalli, M., Korneliussen, T. S., Andersen, M. A., Nielsen, T. S., Krarup, N. T., Gjesing, A. M. P., Zierath, J. R., Linneberg, A., Wu, X., Sun, G., Jin, X., Al-Aama, J., Wang, J., Borch-Johnsen, K., Pedersen, O. & 3 others, , 2014, In: Nature. 512, 7513, p. 190-193 4 p.Research output: Contribution to journal › Letter › Research › peer-review
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A comprehensive map of human glucokinase variant activity
Andersen, Sarah Gersing, Cagiada, Matteo, Gebbia, M., Gjesing, A. P., Coté, A. G., Seesankar, G., Li, R., Tabet, D., Weile, J., Stein, Amelie, Gloyn, A. L., Hansen, Torben, Roth, F. P., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2023, In: Genome Biology. 24, 1, 23 p., 97.Research output: Contribution to journal › Journal article › Research › peer-review
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A computational framework to integrate high-throughput "-omics" datasets for the identification of potential mechanistic links
Pedersen, H. K., Forslund, S. K., Gudmundsdottir, V., Petersen, A. Ø., Hildebrand, F., Hyötyläinen, T., Nielsen, T., Hansen, Torben, Bork, P., Ehrlich, S. D., Brunak, Søren, Oresic, M., Pedersen, Oluf Borbye & Nielsen, H. B., 2018, In: Nature Protocols. 13, 12, p. 2781-2800 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A diet-induced gut microbiota component and related plasma metabolites are associated with depressive-like behaviour in rats
Abildgaard, A., Kern, T., Pedersen, Oluf Borbye, Hansen, Torben, Lund, S. & Wegener, G., 2021, In: European Neuropsychopharmacology. 43, p. 10-21Research output: Contribution to journal › Journal article › Research › peer-review
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A functional amino acid substitution in the glucose-dependent insulinotropic polypeptide receptor (GIPR) gene is associated with lower bone mineral density and increased fracture risk
Torekov, Signe Sørensen, Harsløf, T., Rejnmark, L., Eiken, P., Jensen, Jens-Erik Beck, Herman, A. P., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul & Langdahl, B. L., Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 4, p. E729-33 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A genome-wide association search for type 2 diabetes genes in African Americans
Palmer, N. D., McDonough, C. W., Hicks, P. J., Roh, B. H., Wing, M. R., An, S. S., Hester, J. M., Cooke, J. N., Bostrom, M. A., Rudock, M. E., Talbert, M. E., Lewis, J. P., Ferrara, A., Lu, L., Ziegler, J. T., Sale, M. M., Divers, J., Shriner, D., Adeyemo, A., Rotimi, C. N. & 31 others, , 2012, In: P L o S One. 7, 1, p. e29202Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes
Van Zuydam, N. R., Ahlqvist, E., Sandholm, N., Deshmukh, H., William Rayner, N., Abdalla, M., Ladenvall, C., Ziemek, D., Fauman, E., Robertson, N. R., McKeigue, P. M., Valo, E., Forsblom, C., Harjutsalo, V., Perna, A., Rurali, E., Loredana Marcovecchio, M., Igo, R. P., Lajer, M., Ahluwalia, T. S. & 7 others, , 2018, In: Diabetes. 67, 7, p. 1414-1427 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents
Nielsen, T. R. H., Appel, E. V. R., Svendstrup, M., Ohrt, J. D., Dahl, M., Fonvig, C. E., Hollensted, M., Have, C. T., Kadarmideen, H. N., Pedersen, Oluf Borbye, Hansen, Torben, Holm, Jens-Christian & Grarup, Niels, 2017, In: PloS one. 12, 3, 16 p., e0174204.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease
Scott, R. A., Freitag, D. F., Li, L., Chu, A. Y., Surendran, P., Young, R., Grarup, N., Stancakova, A., Chen, Y., Varga, T. V., Yaghootkar, H., Luan, J., Zhao, J. H., Willems, S. M., Wessel, J., Wang, S., Maruthur, N., Michailidou, K., Pirie, A., van der Lee, S. J. & 119 others, , 1 Jun 2016, In: Science Translational Medicine. 8, 341, 13 p., 341ra76.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
Stacey, S. N., Sulem, P., Jonasdottir, A., Masson, G., Gudmundsson, J., Gudbjartsson, D. F., Magnusson, O. T., Gudjonsson, S. A., Sigurgeirsson, B., Thorisdottir, K., Ragnarsson, R., Benediktsdottir, K. R., Nexø, B. A., Tjønneland, A., Overvad, K., Rudnai, P., Gurzau, E., Koppova, K., Hemminki, K., Corredera, C. & 31 others, , 1 Jan 2011, In: Nature Genetics. 43, 11, p. 1098-1103 6 p.Research output: Contribution to journal › Letter › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Estimation of allele frequency and association mapping using next-generation sequencing data
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