Hansen Group

Evidence for shared genetics between physical activity, sedentary behaviour and adiposity-related traits

Schnurr, T. M., Stallknecht, Bente Merete, Sørensen, Thorkild I.A., Kilpeläinen, Tuomas O. & Hansen, Torben, 2021, In: Obesity Reviews. 22, 4, 12 p., e13182.

Research output: Contribution to journal › Journal article › Research › peer-review

Explaining deep neural networks for knowledge discovery in electrocardiogram analysis

Hicks, S. A., Isaksen, Jonas L., Thambawita, V., Ghouse, Jonas, Ahlberg, Gustav, Linneberg, Allan René, Grarup, Niels, Strümke, I., Ellervik, Christina, Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., von Holstein-Rathlou, Niels-Henrik, Halvorsen, P., Maleckar, M. M., Riegler, M. A. & Kanters, Jørgen K., 2021, In: Scientific Reports. 11, 1, 11 p., 10949.

Research output: Contribution to journal › Journal article › Research › peer-review

FGL1 as a modulator of plasma D-dimer levels: exome-wide marker analysis of plasma tPA, PAI-1 and D-dimer

Thibord, F., Song, C., Pattee, J., Rodriguez, B. A. T., Chen, M-H., O'Donnell, C. J., Kleber, M. E., Delgado, G. E., Guo, X., Yao, J., Taylor, K. D., Ozel, A. B., Brody, J. A., McKnight, B., Gyorgy, B., Simonsick, E., Leonard, H. L., Carrasquilla, G. D., Guindo-Martinez, M., Silveira, A. & 30 others, Temprano-Sagrera, G., Yanek, L. R., Becker, D. M., Mathias, R. A., Becker, L. C., Raffield, L. M., Kilpeläinen, Tuomas O., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Hamsten, A., Watkins, H., Sabater-Lleal, M., Nalls, M. A., Trégouët, D., Morange, P., Psaty, B. M., Tracy, R. P., Smith, N. L., Desch, K. C., Cushman, M., Rotter, J. I., de Vries, P. S., Pankratz, N. D., Folsom, A. R., Morrison, A. C., März, W., Tang, W. & Johnson, A. D., 2021, In: Journal of Thrombosis and Haemostasis. 19, 8, p. 2019-2028

Research output: Contribution to journal › Journal article › Research › peer-review

Fasting plasma GLP-1 associates with overweight/obesity and cardiometabolic risk factors in children and adolescents

Stinson, Sara, Jonsson, Anna Elisabet, Lund, M. A. V., Frithioff-Bøjsøe, C., Holm, L. A., Pedersen, Oluf Borbye, Ängquist, Lars, Sørensen, Thorkild I.A., Holst, Jens Juul, Christiansen, M., Holm, Jens-Christian, Hartmann, Bolette & Hansen, Torben, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 6, p. 1718-1727

Research output: Contribution to journal › Journal article › Research › peer-review

Fecal microbiota transplantation in hepatic encephalopathy: a systematic review

Madsen, M., Kimer, N., Bendtsen, Flemming & Petersen, Andreas Munk, 2021, In: Scandinavian Journal of Gastroenterology. 56, 5, p. 560-569 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Fish oil replacement prevents, while docosahexaenoic acid-derived protectin DX mitigates end-stage-renal-disease in atherosclerotic diabetic mice

Perazza, L. R., Mitchell, P. L., Lizotte, F., Jensen, Benjamin Anderschou Holbech, St-Pierre, P., Trottier, J., Barbier, O., Mathieu, P., Geraldes, P. M. & Marette, A., 2021, In: FASEB Journal. 35, 5, 18 p., 21559.

Research output: Contribution to journal › Journal article › Research › peer-review

Fungal lysozyme leverages the gut microbiota to curb DSS-induced colitis

Larsen, I. S., Jensen, Benjamin Anderschou Holbech, Bonazzi, E., Choi, Beatrice So-Yun, Kristensen, N. N., Schmidt, E. G. W., Süenderhauf, A., Morin, L., Olsen, P. B., Hansen, L. B. S., Schröder, T., Sina, C., Chassaing, B. & Marette, A., 2021, In: Gut Microbes. 13, 1, 20 p., 1988836.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic markers of abdominal obesity and weight loss after gastric bypass surgery

Aasbrenn, M., Svendstrup, M., Schnurr, T. M., Hansen, D. L., Worm, Dorte, Balslev-Harder, M., Grarup, Niels, Burgdorf, Kristoffer Sølvsten, drb459, drb459, Pedersen, Oluf Borbye, Ängquist, Lars, Fenger, M., Sørensen, Thorkild I.A., Madsbad, Sten & Hansen, Torben, 2021, In: PLoS ONE. 16, 5, 11 p., 0252525.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity

Deshmukh, H. A., Madsen, A. L., Viñuela, A., Have, C. T., Grarup, N., Tura, A., Mahajan, A., Heggie, A. J., Koivula, R. W., De Masi, F., Tsirigos, K. K., Linneberg, A., Drivsholm, T., Pedersen, O., Sørensen, T. I. A., Astrup, A., Gjesing, A. A. P., Pavo, I., Wood, A. R., Ruetten, H. & 14 others, Jones, A. G., Koopman, A. D. M., Cederberg, H., Rutters, F., Ridderstrale, M., Laakso, M., McCarthy, M. I., Frayling, T. M., Ferrannini, E., Franks, P. W., Pearson, E. R., Mari, A., Hansen, T. & Walker, M., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 1, p. 80-90 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study identifies novel susceptibility loci for KIT D816V positive mastocytosis

Galatà, G., García-Montero, A. C., Kristensen, T., Dawoud, A. A. Z., Muñoz-González, J. I., Meggendorfer, M., Guglielmelli, P., Hoade, Y., Alvarez-Twose, I., Gieger, C., Strauch, K., Ferrucci, L., Tanaka, T., Bandinelli, S., Schnurr, T. M., Haferlach, T., Broesby-Olsen, S., Vestergaard, H., Møller, M. B., Bindslev-Jensen, C. & 7 others, Vannucchi, A. M., Orfao, A., Radia, D., Reiter, A., Chase, A. J., Cross, N. C. P. & Tapper, W. J., 2021, In: American Journal of Human Genetics. 108, 2, p. 284-294 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test

Jonsson, Anna Elisabet, Stinson, Sara, Torekov, Signe Sørensen, Clausen, Tine Dalsgaard, Færch, K., Kelstrup, Louise, Grarup, Niels, Mathiesen, Elisabeth, Damm, Peter, Witte, D. R., Jørgensen, M. E., Pedersen, Oluf Borbye, Holst, Jens Juul & Hansen, Torben, 2021, In: BMC Medical Genomics. 14, 7 p., 3.

Research output: Contribution to journal › Journal article › Research › peer-review

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

Min, J. L., Hemani, G., Hannon, E., Dekkers, K. F., Castillo-Fernandez, J., Luijk, R., Carnero-Montoro, E., Lawson, D. J., Burrows, K., Suderman, M., Bretherick, A. D., Richardson, T. G., Klughammer, J., Iotchkova, V., Sharp, G., Al Khleifat, A., Shatunov, A., Iacoangeli, A., McArdle, W. L., Ho, K. M. & 31 others, Kumar, A., Söderhäll, C., Soriano-Tárraga, C., Giralt-Steinhauer, E., Kazmi, N., Mason, D., McRae, A. F., Corcoran, D. L., Sugden, K., Kasela, S., Cardona, A., Day, F. R., Cugliari, G., Viberti, C., Guarrera, S., Lerro, M., Gupta, R., Bollepalli, S., Mandaviya, P., Zeng, Y., Clarke, T. K., Walker, R. M., Schmoll, V., Czamara, D., Ruiz-Arenas, C., Elliott, H. R., Nohr, E. A., Sørensen, Thorkild I.A., Hansen, Torben, Morgen, C. S. & BIOS Consortium, B. C., 2021, In: Nature Genetics. 53, 9, p. 1311-1321 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Glucagon-Like Peptide-1 Is Associated With Systemic Inflammation in Pediatric Patients Treated With Hematopoietic Stem Cell Transplantation

Sørum, Maria Ebbesen, Kissow, Hannelouise, Hartmann, Bolette, Kielsen, K., Sørensen, K., Stinson, Sara, Frithioff-Bojsoe, C., Fonvig, Cilius Esmann, Holm, Jens-Christian, Hansen, Torben, Holst, Jens Juul & Müller, K. G., 2021, In: Frontiers in Immunology. 12, 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

HBD-2 mutations are associated with childhood asthma and prophylactic hBD-2 application prevents asthma in mice

Borchers, N., Santos-Valente, E., Toncheva, A. A., Wehkamp, J., Franke, A., Gaertner, V. D., Nordkild, P., Genuneit, J., Jensen, Benjamin Anderschou Holbech & Kabesch, M., 2021, In: European Respiratory Journal. 58, Suppl. 65, 2 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Human Milk Oligosaccharides Modulate Fecal Microbiota and Are Safe for Use in Children With Overweight: A Randomized Controlled Trial

Fonvig, Cilius Esmann, Amundsen, I. D., Vigsnæs, L. K., Sørensen, N., Frithioff-Bojsoe, C., Christiansen, M., Hedley, P. L., Holm, L. A., McConnell, B. & Holm, Jens-Christian, 2021, In: Journal of Pediatric Gastroenterology and Nutrition. 73, 3, p. 408-414 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Human and preclinical studies of the host-gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health

Brial, F., Chilloux, J., Nielsen, T., Vieira-Silva, S., Falony, G., Andrikopoulos, P., Olanipekun, M., Hoyles, L., Djouadi, F., Neves, A. L., Rodriguez-Martinez, A., Mouawad, G. I., Pons, N., Forslund, S., Le-chatelier, E., Le Lay, A., Nicholson, J., Hansen, T., Hyotylainen, T., Clement, K. & 7 others, Oresic, M., Bork, P., Ehrlich, S. D., Raes, J., Pedersen, Oluf Borbye, Gauguier, D. & Dumas, M., 2021, In: Gut. 70, 11, p. 2105-2114 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Human beta-defensin-2 suppresses key features of asthma in murine models of allergic airways disease

Pinkerton, J. W., Kim, R. Y., Koeninger, L., Armbruster, N. S., Hansbro, N. G., Brown, A. C., Jayaraman, R., Shen, S., Malek, N., Cooper, M. A., Nordkild, P., Horvat, J. C., Jensen, Benjamin Anderschou Holbech, Wehkamp, J. & Hansbro, P. M., 2021, In: Clinical and Experimental Allergy. 51, 1, p. 120-131 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Human skeletal muscle CD90⁺ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

Farup, J., Just, J., de Paoli, F., Lin, L., Jensen, J. B., Billeskov, T., Roman, I. S., Cömert, C., Møller, A. B., Madaro, L., Groppa, E., Fred, R. G., Kampmann, U., Gormsen, L. C., Pedersen, S. B., Bross, P., Stevnsner, T., Eldrup, N., Pers, T. H., Rossi, F. M. V. & 2 others, Puri, P. L. & Jessen, N., 2021, In: Cell Metabolism. 33, 11, p. 2201-2214.e11

Research output: Contribution to journal › Journal article › Research › peer-review

Human β-Defensin 2 Mutations Are Associated With Asthma and Atopy in Children and Its Application Prevents Atopic Asthma in a Mouse Model

Borchers, N. S., Santos-Valente, E., Toncheva, A. A., Wehkamp, J., Franke, A., Gaertner, V. D., Nordkild, P., Genuneit, J., Jensen, Benjamin Anderschou Holbech & Kabesch, M., 2021, In: Frontiers in Immunology. 12, 12 p., 636061.

Research output: Contribution to journal › Journal article › Research › peer-review

Instrumental variable analysis using offspring BMI in childhood as an indicator of parental BMI in relation to mortality

Blond, K., Carslake, D., Gjærde, L. K., Vistisen, D., Sørensen, Thorkild I.A., Smith, G. D. & Baker, J. L., 2021, In: Scientific Reports. 11, 1, 10 p., 22408.

Research output: Contribution to journal › Journal article › Research › peer-review

Insulin resistance genetic risk score and burden of coronary artery disease in patients referred for coronary angiography

Skals, R., Krogager, M. L., Appel, E. V. R., Schnurr, T. M., Have, C. T., Gislason, Gunnar Hilmar, Poulsen, Henrik Enghusen, Køber, Lars Valeur, Engstrøm, Thomas, Stender, Steen, Hansen, Torben, Grarup, Niels, Lee, C. J., Andersson, C., Torp-Pedersen, Christian & Weeke, P. E., 2021, In: PLoS ONE. 16, 6, 11 p., 0252855.

Research output: Contribution to journal › Journal article › Research › peer-review

Isolation and characterization of muscle stem cells, fibro-adipogenic progenitors, and macrophages from human skeletal muscle biopsies

Jensen, J. B., Møller, A. B., Just, J., Mose, M., de Paoli, F. V., Billeskov, T. B., Fred, Rikard Göran, Pers, Tune H, Pedersen, S. B., Petersen, K. K., Bjerre, M., Farup, J. & Jessen, N., 2021, In: American Journal of Physiology - Cell Physiology. 321, 2, p. C257-C268 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Large-scale association analyses identify host factors influencing human gut microbiome composition

Kurilshikov, A., Medina-Gomez, C., Bacigalupe, R., Radjabzadeh, D., Wang, J., Demirkan, A., Le Roy, C. I., Raygoza Garay, J. A., Finnicum, C. T., Liu, X., Zhernakova, D. V., Bonder, M. J., Hansen, T. H., Frost, F., Rühlemann, M. C., Turpin, W., Moon, J. Y., Kim, H. N., Lüll, K., Barkan, E. & 84 others, Shah, S. A., Fornage, M., Szopinska-Tokov, J., Wallen, Z. D., Borisevich, D., Agreus, L., Andreasson, A., Bang, C., Bedrani, L., Bell, J. T., Bisgaard, H., Boehnke, M., Boomsma, D. I., Burk, R. D., Claringbould, A., Croitoru, K., Davies, G. E., van Duijn, C. M., Duijts, L., Falony, G., Fu, J., van der Graaf, A., Hansen, Torben, Homuth, G., Hughes, D. A., Ijzerman, R. G., Jackson, M. A., Jaddoe, V. W. V., Joossens, M., Jørgensen, T., Keszthelyi, D., Knight, R., Laakso, M., Laudes, M., Launer, L. J., Lieb, W., Lusis, A. J., Masclee, A. A. M., Moll, H. A., Mujagic, Z., Qibin, Q., Rothschild, D., Shin, H., Sørensen, Søren Johannes, Steves, C. J., Thorsen, Jonathan Jan Ilve, Timpson, N. J., Tito, R. Y., Vieira-Silva, S., Völker, U., Völzke, H., Võsa, U., Wade, K. H., Walter, S., Watanabe, K., Weiss, S., Weiss, F. U., Weissbrod, O., Westra, H. J., Willemsen, G., Payami, H., Jonkers, D. M. A. E., Arias Vasquez, A., de Geus, E. J. C., Meyer, K. A., Stokholm, Jakob, Segal, E., Org, E., Wijmenga, C., Kim, H. L., Kaplan, R. C., Spector, T. D., Uitterlinden, A. G., Rivadeneira, F., Franke, A., Lerch, M. M., Franke, L., Sanna, S., D’Amato, M., Pedersen, Oluf Borbye, Paterson, A. D., Kraaij, R., Raes, J. & Zhernakova, A., 2021, In: Nature Genetics. 53, p. 156-165 19 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, Orchard, W., Willemsen, N., Jespersen, N. Z., Lundh, M., Sustarsic, E. G., Hallgren, C. M., Frost, M., McGonigle, S., Isidor, Marie Sophie, Broholm, C., Pedersen, Oluf Borbye, Hansen, Jacob B., Grarup, Niels, Hansen, Torben, Kjær, Andreas, Granneman, J. G., Babu, M. M., Calebiro, D., Nielsen, S., Rydén, M., Soccio, R., Rensen, P. C. N., Treebak, Jonas Thue, Schwartz, Thue W., Emanuelli, Brice, Bartolomucci, A., Pfeifer, A., Zechner, R., Schéele, Camilla Charlotte Nielsen, Mandrup, S. & Gerhart-Hines, Z., 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3⁺RORγt⁺IL-17⁺ Tregs and improve metabolism

Jensen, B. A. H., Holm, J. B., Larsen, I. S., von Burg, N., Derer, S., Sonne, S. B., Pærregaard, S. I., Damgaard, M. V., Indrelid, S. A., Rivollier, A., Agrinier, A. L., Sulek, K., Arnoldussen, Y. J., Fjære, E., Marette, A., Angell, I. L., Rudi, K., Treebak, J. T., Madsen, L., Åkesson, C. P. & 5 others, Agace, W., Sina, C., Kleiveland, C. R., Kristiansen, Karsten & Lea, T. E., 2021, In: Nature Communications. 12, 19 p., 1093.

Research output: Contribution to journal › Journal article › Research › peer-review

Mapping the human genetic architecture of COVID-19

Niemi, M. E. K., Karjalainen, J., Liao, R. G., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Andrews, S. J., Kanai, M., Veerapen, K., Fernandez-Cadenas, I., Schulte, E. C., Striano, P., Marttila, M., Minica, C., Marouli, E., Karim, M. A., Wendt, F. R., Savage, J., Sloofman, L. & 41 others, Butler-Laporte, G., Kim, H., Kanoni, S., Okada, Y., Byun, J., Han, Y., Uddin, M. J., Smith, G. D., Willer, C. J., Buxbaum, J. D., Karjalainen, J., Mehtonen, J., Folkersen, L., Moltke, Ida, Hinney, A., Wang, C., Ellinghaus, D., Brunak, Søren, Castro, P., Guindo Martínez, Marta, Lee, J. Y., Loos, Ruth, Zhao, J. H., Sun, Y. V., Wang, B., Parker, R., Garcia, S. M., Smith, O., Davis, C., COVID-19 Host Genetics Initiative, C. H. G. I., 23andMe COVID-19 Team, 2. C. T., Norwegian SARS-CoV-2 Study Grp, N. S. S. G., Humanitas COVID-19 Task Force, H. C. T. F., Humanitas Gavazzeni COVID-19 Task, H. G. C. T., FHoGID, F., RegCOVID, R., P-PredictUs, P., SeroCOVID, S., CRiPSI, C., Genes & Hlth Res Team, G. &. H. R. T. & UCLA Hlth ATLAS Data Mart Working, U. H. A. D. M. W., 2021, In: Nature. 600, p. 472-477

Research output: Contribution to journal › Journal article › Research › peer-review

Non-linear interaction between physical activity and polygenic risk score of body mass index in Danish and Russian populations

Borisevich, D., Schnurr, T. M., pjx571, pjx571, Rakitko, A., Ängquist, Lars, Ilinsky, V., Aadahl, Mette, Grarup, Niels, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Hansen, Torben, 2021, In: PLoS ONE. 16, 10, 16 p., e0258748.

Research output: Contribution to journal › Journal article › Research › peer-review

Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: Overlapping Mechanisms

Møller, Søren, Kimer, N., Kronborg, T., Grandt, J., Hove, Jens Dahlgaard, Barløse, Mads Christian Johannes & Gluud, Lise Lotte, 2021, In: Seminars in Liver Disease. 41, 03, p. 235-247

Research output: Contribution to journal › Journal article › Research › peer-review

Novel Anti-inflammatory Treatments in Cirrhosis. A Literature-Based Study

Kronborg, T. M., Lambert, Henriette Ytting, Hobolth, L., Møller, Søren & Kimer, N., 2021, In: Frontiers in Medicine. 8, 718896.

Research output: Contribution to journal › Review › Research › peer-review

Obesity treatment effect in Danish children and adolescents carrying Melanocortin-4 Receptor mutations

Trier, C., Hollensted, M., Schnurr, T. M., Lund, Morten Asp Vonsild, Nielsen, T. R. H., Rui, G., Andersson, E. A., Svendstrup, M., Bille, D. S., Gjesing, A. P., Fonvig, Cilius Esmann, Frithioff-Bojsoe, C., Balslev-Harder, M., Quan, S., Gamborg, Michael Orland, Pedersen, Oluf Borbye, Ängquist, Lars, Holm, Jens-Christian & Hansen, Torben, 2021, In: International Journal of Obesity. 45, p. 66-76 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers

Schnurr, T. M., Jørsboe, E., Chadt, A., Dahl-Petersen, I. K., Kristensen, Jonas Møller, Wojtaszewski, Jørgen F P, Springer, C., Bjerregaard, P., Brage, S., Pedersen, Oluf Borbye, Moltke, Ida, Grarup, Niels, Al-Hasani, H., Albrechtsen, Anders, Jørgensen, M. E. & Hansen, Torben, 2021, In: Diabetologia. 64, p. 1795-1804

Research output: Contribution to journal › Journal article › Research › peer-review

Population-based pediatric reference values for serum parathyroid hormone, vitamin D, calcium, and phosphate in Danish/North-European white children and adolescents

Vissing Landgrebe, A., Lund, Morten Asp Vonsild, Lausten-Thomsen, U., Frithioff-Bøjsøe, C., Fonvig, Cilius Esmann, Lind Plesner, J., Aas Holm, L., Jespersen, Thomas, Hansen, Torben & Holm, Jens-Christian, 2021, In: Clinica Chimica Acta. 523, p. 483-490

Research output: Contribution to journal › Journal article › Research › peer-review

Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study

Bizzotto, R., Jennison, C., Jones, A. G., Kurbasic, A., Tura, A., Kennedy, G., Bell, J. D., Thomas, E. L., Frost, G., Eriksen, R., Koivula, R. W., Brage, S., Kaye, J., Hattersley, A. T., Heggie, A., McEvoy, D., 't Hart, L. M., Beulens, J. W., Elders, P., Musholt, P. B. & 28 others, Ridderstrale, M., Hansen, T. H., Allin, K. H., Hansen, Torben, drb459, drb459, Lundgaard, Agnete Troen, Thomsen, Henrik S., De Masi, F., Tsirigos, Konstantinos, Brunak, Søren, Vinuela, A., Mahajan, A., McDonald, T. J., Kokkola, T., Forgie, I. M., Giordano, G. N., Pavo, I., Ruetten, H., Dermitzakis, E., McCarthy, M. I., Pedersen, Oluf Borbye, Schwenk, J. M., Adamski, J., Franks, P. W., Walker, M., Pearson, E. R., Mari, A. & IMI-DIRECT consortium, I. C., 2021, In: Diabetes Care. 44, 2, p. 511-518 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Profiles of glucose metabolism in different prediabetes phenotypes, classified by fasting glycemia, 2-hour OGTT, glycated hemoglobin, and 1-hour OGTT: An IMI DIRECT study

Tura, A., Grespan, E., Göbl, C. S., Koivula, R. W., Franks, P. W., Pearson, E. R., Walker, M., Forgie, I. M., Giordano, G. N., Pavo, I., Ruetten, H., Dermitzakis, E. T., McCarthy, M. I., Pedersen, O., Schwenk, J. M., Adamski, J., De Masi, F., Tsirigos, K. D., Brunak, S., Viñuela, A. & 17 others, Mahajan, A., McDonald, T. J., Kokkola, T., Vangipurapu, J., Cederberg, H., Laakso, M., Rutters, F., Elders, P. J. M., Koopman, A. D. M., Beulens, J. W., Ridderstråle, M., Hansen, T. H., Allin, K. H., Hansen, Torben, drb459, drb459, Mari, A. & IMI-DIRECT consortium, I. C., 2021, In: Diabetes. 70, 6, db210227.

Research output: Contribution to journal › Journal article › Research › peer-review

Prognostic performance of 7 biomarkers compared to liver biopsy in early alcohol-related liver disease

Rasmussen, D. N., Thiele, M., Johansen, S., Kjærgaard, M., Lindvig, K. P., Israelsen, M., Antonsen, S., Detlefsen, S., Krag, A., Anastasiadou, E., Arumugam, M., Bork, P., Hansen, T., Hartoft, C., Israelsen, H., Karsdal, M., Legido-Quigley, C., Melberg, H. O., Trebicka, J., Mann, M. & 2 others, Matthijnssens, J. & MicrobLiver consortia, M. C., 2021, In: Journal of Hepatology. 75, 5, p. 1017-1025 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Protein intake, metabolic status and the gut microbiota in different ethnicities: Results from two independent cohorts

Bel Lassen, P., Attaye, I., Adriouch, S., Nicolaou, M., Aron-Wisnewsky, J., Nielsen, T., Chakaroun, R., Le Chatelier, E., Forslund, S., Belda, E., Bork, P., Bäckhed, F., Stumvoll, M., Pedersen, O., Herrema, H., Groen, A. K., Pinto-Sietsma, S. J., Zwinderman, A. H., Nieuwdorp, M., Clement, K. & 1 others, MetaCardis Consortium, M. C., 2021, In: Nutrients. 13, 9, 3159.

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Reply to: “Dietary sucrose induces atherosclerotic diseases more than dietary fat in LDLr^−/− ApoB^100/100 mice: Is it independent of differences in plasma cholesterol levels?”

Perazza, L. R., Daniel, N., Mitchell, P. L., Jensen, Benjamin Anderschou Holbech & Marette, A., 2021, In: Atherosclerosis. 325, p. 118-120 3 p.

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Revision rates of trapeziometacarpal total joint arthroplasty in relation to occupational hand force requirements

Kirkeby, L., Frost, Poul, Svendsen, S. W. & Hansen, Torben, 2021, In: Journal of Hand Surgery: European Volume. 46, 9, p. 968-974 7 p.

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The effect of melatonin on incretin hormones: results from experimental and randomized clinical studies

Lauritzen, E. S., Støy, J., Bæch-Laursen, C., Grarup, Niels, Jessen, N., Hansen, Torben, Møller, N., Hartmann, Bolette, Holst, Jens Juul & Kampmann, U., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 12, p. e5109-e5123 15 p.

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The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study

Eloranta, A-M., Sallinen, T., Viitasalo, A., Lintu, N., Väistö, J., Jalkanen, H., Tompuri, T. T., Soininen, S., Haapala, E. A., Kiiskinen, S., Schnurr, T. M., Kilpeläinen, T. O., Mikkonen, S., Savonen, K., Atalay, M., Brage, S., Laaksonen, D. E., Lindi, V., Ågren, J., Schwab, U. & 2 others, Jääskeläinen, J. & Lakka, T. A., 2021, In: European Journal of Nutrition. 60, p. 425-434

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The genetic history of Greenlandic-European contact

Waples, R. K., Hauptmann, A. L., Seiding, I. H., Jørsboe, E., Jørgensen, M. E., Grarup, Niels, Andersen, M. K., Larsen, C. V. L., Bjerregaard, P., Hellenthal, G., Hansen, Torben, Albrechtsen, Anders & Moltke, Ida, 2021, In: Current Biology. 31, 10, p. 2214-2219.e4

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The power of genetic diversity in genome-wide association studies of lipids

Graham, S. E., Clarke, S. L., Wu, K-H. H., Kanoni, S., Zajac, G. J. M., Ramdas, S., Surakka, I., Ntalla, I., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Hwang, M. Y., Han, S., Narita, A., Choudhury, A., Bentley, A. R., Ekoru, K., Verma, A., Trivedi, B. & 504 others, Martin, H. C., Hunt, K. A., Hui, Q., Klarin, D., Zhu, X., Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Akiyama, M., Sakaue, S., Terao, C., Kanai, M., Zhou, W., Brumpton, B. M., Rasheed, H., Ruotsalainen, S. E., Havulinna, A. S., Veturi, Y., Feng, Q., Rosenthal, E. A., Lingren, T., Pacheco, J. A., Pendergrass, S. A., Haessler, J., Giulianini, F., Bradford, Y., Miller, J. E., Campbell, A., Lin, K., Millwood, I. Y., Hindy, G., Rasheed, A., Faul, J. D., Zhao, W., Weir, D. R., Turman, C., Huang, H., Graff, M., Mahajan, A., Brown, M. R., Zhang, W., Yu, K., Schmidt, E. M., Pandit, A., Gustafsson, S., Yin, X., Luan, J., Zhao, J., Matsuda, F., Jang, H., Yoon, K., Medina-Gomez, C., Pitsillides, A., Hottenga, J. J., Willemsen, G., Wood, A. R., Ji, Y., Gao, Z., Haworth, S., Mitchell, R. E., Chai, J. F., Aadahl, Mette, Yao, J., Manichaikul, A., Warren, H. R., Ramirez, J., Bork-Jensen, J., Karhus, L. L., Goel, A., Sabater-Lleal, M., Noordam, R., Sidore, C., Fiorillo, E., McDaid, A. F., Marques-Vidal, P., Wielscher, M., Trompet, S., Sattar, N., Møllehave, Line Tang, Thuesen, B. H., Munz, M., Zeng, L., Huang, J., Yang, B., Poveda, A., Kurbasic, A., Lamina, C., Forer, L., Scholz, M., Galesloot, T. E., Bradfield, J. P., Daw, E. W., Zmuda, J. M., Mitchell, J. S., Fuchsberger, C., Christensen, H., Brody, J. A., Feitosa, M. F., Wojczynski, M. K., Preuss, M., Mangino, M., Christofidou, P., Verweij, N., Benjamins, J. W., Engmann, J., Kember, R. L., Slieker, R. C., Lo, K. S., Zilhao, N. R., Phuong Le, Kleber, M. E., Delgado, G. E., Huo, S., Ikeda, D. D., Iha, H., Yang, J., Liu, J., Leonard, H. L., Marten, J., Schmidt, B., Arendt, M., Smyth, L. J., Canadas-Garre, M., Wang, C., Nakatochi, M., Wong, A., Hutri-Kahonen, N., Sim, X., Xia, R., Huerta-Chagoya, A., Fernandez-Lopez, J. C., Lyssenko, V., Ahmed, M., Jackson, A. U., Irvin, M. R., Oldmeadow, C., Kim, H., Ryu, S., Timmers, P. R. H. J., Arbeeva, L., Dorajoo, R., Lange, L. A., Chai, X., Prasad, G., Lores-Motta, L., Pauper, M., Long, J., Li, X., Theusch, E., Takeuchi, F., Spracklen, C. N., Loukola, A., Bollepalli, S., Warner, S. C., Wang, Y. X., Wei, W. B., Nutile, T., Ruggiero, D., Sung, Y. J., Hung, Y., Chen, S., Liu, F., Yang, J., Kentistou, K. A., Gorski, M., Brumat, M., Meidtner, K., Bielak, L. F., Smith, J. A., Hebbar, P., Farmaki, A., Hofer, E., Lin, M., Xue, C., Zhang, J., Concas, M. P., Vaccargiu, S., van der Most, P. J., Pitkanen, N., Cade, B. E., Lee, J., van Der Laan, S. W., Chitrala, K. N., Weiss, S., Zimmermann, M. E., Lee, J. Y., Choi, H. S., Nethander, M., Freitag-Wolf, S., Southam, L., Rayner, N. W., Wang, C. A., Lin, S., Wang, J., Couture, C., Lyytikainen, L., Nikus, K., Cuellar-Partida, G., Vestergaard, H., Hildalgo, B., Giannakopoulou, O., Cai, Q., Obura, M. O., van Setten, J., Li, X., Schwander, K., Terzikhan, N., Shin, J. H., Jackson, R. D., Reiner, A. P., Martin, L. W., Chen, Z., Li, L., Highland, H. M., Young, K. L., Kawaguchi, T., Thiery, J., Bis, J. C., Nadkarni, G. N., Launer, L. J., Li, H., Nalls, M. A., Raitakari, O. T., Ichihara, S., Wild, S. H., Nelson, C. P., Campbell, H., Jager, S., Nabika, T., Al-Mulla, F., Niinikoski, H., Braund, P. S., Kolcic, I., Kovacs, P., Giardoglou, T., Katsuya, T., Bhatti, F., de Kleijn, D., de Borst, G. J., Kim, E. K., Adams, H. H. H., Ikram, M. A., Zhu, X., Asselbergs, F. W., Kraaijeveld, A. O., Beulens, J. W. J., Shu, X., Rallidis, L. S., Pedersen, Oluf Borbye, Hansen, Torben, Mitchell, P., Hewitt, A. W., Kahonen, M., Perusse, L., Bouchard, C., Tonjes, A., Chen, Y. 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C., Arnett, D. K., Walker, M., Koistinen, H. A., Chandak, G. R., Yajnik, C. S., Mercader, J. M., Tusie-Luna, T., Aguilar-Salinas, C. A., Villalpando, C. G., Orozco, L., Fornage, M., Tai, E. S., van Dam, R. M., Lehtimaki, T., Chaturvedi, N., Yokota, M., Liu, J., Reilly, D. F., McKnight, A. J., Kee, F., Jockel, K., McCarthy, M. I., Palmer, C. N. A., Vitart, V., Hayward, C., Simonsick, E., van Duijn, C. M., Lu, F., Qu, J., Hishigaki, H., Lin, X., Marz, W., Parra, E. J., Cruz, M., Gudnason, V., Tardif, J., Lettre, G., 't Hart, L. M., Elders, P. J. M., Damrauer, S. M., Kumari, M., Kivimaki, M., van der Harst, P., Spector, T. D., Loos, R. J. F., Province, M. A., Psaty, B. M., Brandslund, I., Pramstaller, P. P., Christensen, K., Ripatti, S., Widen, E., Hakonarson, H., Grant, S. F. A., Kiemeney, L. A. L. M., de Graaf, J., Loeffler, M., Kronenberg, F., Gu, D., Erdmann, J., Schunkert, H., Franks, P. W., Linneberg, Allan René, Jukema, J. W., Khera, A. V., Mannikko, M., Jarvelin, M., Kutalik, Z., Cucca, F., Mook-Kanamori, D. O., van Dijk, K. W., Watkins, H., Strachan, D. P., Grarup, Niels, Sever, P., Poulter, N., Rotter, J. I., Dantoft, T. M., Karpe, F., Neville, M. J., Timpson, N. J., Cheng, C., Wong, T., Khor, C. C., Sabanayagam, C., Peters, A., Gieger, C., Hattersley, A. T., Pedersen, N. L., Magnusson, P. K. E., Boomsma, D. I., de Geus, E. J. C., Cupples, L. A., van Meurs, J. B. J., Ghanbari, M., Rsen, P. G., Huang, W., Kim, Y. J., Tabara, Y., Wareham, N. J., Langenberg, C., Zeggini, E., Kuusisto, J., Laakso, M., Ingelsson, E., Abecasis, G., Chambers, J. C., Kooner, J. S., de Vries, P. S., Morrison, A. C., North, K. E., Daviglus, M., Kraft, P., Martin, N. G., Whitfield, J. B., Abbas, S., Saleheen, D., Walters, R. G., Holmes, M. V., Black, C., Smith, B. H., Justice, A. E., Baras, A., Buring, J. E., Ridker, P. M., Chasman, D. I., Kooperberg, C., Wei, W., Jarvik, G. P., Namjou, B., Hayes, M. G., Ritchie, M. D., Jousilahti, P., Salomaa, V., Hveem, K., Asvold, B. O., Kubo, M., Kamatani, Y., Okada, Y., Murakami, Y., Thorsteinsdottir, U., Stefansson, K., Ho, Y., Lynch, J. A., Rader, D. J., Tsao, P. S., Chang, K., Cho, K., O'Donnell, C. J., Gaziano, J. M., Wilson, P., Rotimi, C. N., Hazelhurst, S., Ramsay, M., Trembath, R. C., van Heel, D. A., Tamiya, G., Yamamoto, M., Kim, B., Mohlke, K. L., Frayling, T. M., Hirschhorn, J. N., Kathiresan, S., Boehnke, M., Natarajan, P., Peloso, G. M., Brown, C. D., Morris, A. P., Assimes, T. L., Deloukas, P., Sun, Y. V. & Willer, C. J., 2021, In: Nature. 600, p. 675-679

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The role of a traditional and western diet on glucose homeostasis in Greenlandic Inuit carriers and non-carriers of type 2 diabetes variant in the TBC1D4 gene: A protocol for a randomized clinical trial

Møller, G., Lind, M. V., Hauptmann, A. L., Senftleber, N., Hansen, C. B., Hansen, Torben, Jørgensen, M. E. & Lauritzen, Lotte, 2021, In: Contemporary Clinical Trials Communications. 21, 6 p., 100734.

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The trans-ancestral genomic architecture of glycemic traits

Chen, J., Spracklen, C. N., Marenne, G., Varshney, A., Corbin, L. J., Luan, J., Willems, S. M., Wu, Y., Zhang, X., Horikoshi, M., Boutin, T. S., Magi, R., Waage, J., Li-Gao, R., Chan, K. H. K., Yao, J., Anasanti, M. D., Chu, A. Y., Claringbould, A., Heikkinen, J. & 31 others, Hong, J., Hottenga, J., Huo, S., Kaakinen, M. A., Louie, T., Maerz, W., Moreno-Macias, H., Ndungu, A., Nelson, S. C., Nolte, I. M., North, K. E., Appel, E. V. R., Liu, J., Sparso, T., Zhao, J., Astrup, A., Jørgensen, M. E., Linneberg, Allan René, Vestergaard, H., Bisgaard, H., Bønnelykke, Klaus, Grarup, Niels, Hansen, Torben, Kovacs, P., Lind, L., Loos, R. J. F., Njølstad, I., Pedersen, Oluf Borbye, Schwarz, Peter, Sørensen, Thorkild I.A. & Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC), M. O. G. A. I. T. C. (., 2021, In: Nature Genetics. 53, 6, p. 840-860 41 p.

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Trans-ethnic gut microbial signatures of prediabetic subjects from India and Denmark

Pinna, N. K., Anjana, R. M., Saxena, S., Dutta, A., Gnanaprakash, V., Rameshkumar, G., Aswath, S., Raghavan, S., Rani, C. S. S., Radha, V., Balasubramanyam, M., Pant, A., Nielsen, T., Jørgensen, T., Færch, K., Kashani, A., Silva, M. C. A., Vestergaard, H., Hansen, T. H., Hansen, T. & 6 others, Arumugam, Mani, Nair, G. B., Das, B., Pedersen, Oluf Borbye, Mohan, V. & Mande, S. S., 2021, In: Genome Medicine. 13, 20 p., 36.

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Trans-ethnic gut microbiota signatures of type 2 diabetes in Denmark and India

Alvarez-Silva, C., Kashani, A., Hansen, T. H., Pinna, N. K., Anjana, R. M., Dutta, A., Saxena, S., Støy, J., Kampmann, U., Nielsen, T., Jørgensen, T., Gnanaprakash, V., Gnanavadivel, R., Sukumaran, A., Rani, C. S. S., Færch, K., Radha, V., Balasubramanyam, M., Nair, G. B., Das, B. & 6 others, drb459, drb459, Hansen, Torben, Mande, S. S., Mohan, V., Arumugam, Mani & Pedersen, Oluf Borbye, 2021, In: Genome Medicine. 13, 37.

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Transcriptome analysis uncover differential regulation in cell cycle, immunity, and metabolism in Anopheles albimanus during immune priming with Plasmodium berghei

Maya-Maldonado, K., Cime-Castillo, J., Maya, Otoniel, Argotte-Ramos, R., Rodríguez, M. C. & Lanz-Mendoza, H., 2021, In: Developmental and Comparative Immunology. 120, 104046.

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r-cubed: Guiding the overwhelmed scientist from random wrangling to Reproducible Research in R

Johnston, L., Juel, H., Lengger, B., Witte, D., Chatwin, H., Christiansen, Malene Revsbech & Isaksen, A., 2021, In: Journal of Open Source Education. 4, 44, 5 p.

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Experience from a COVID-19 first-line referral clinic in Greater Copenhagen

Kronborg, T. M., Kimer, N., Junker, A. E., Werge, M. P., Gluud, Lise Lotte & Ytting, H., 7 Aug 2020, In: Danish Medical Journal. 67, 9, 10 p., A05200343.

Research output: Contribution to journal › Journal article › Research › peer-review