Hansen Group

  1. Published

    In vivo efficacy of HD0471953: A novel GPR119 agonist for the treatment of type 2 diabetes mellitus

    'T Hart, L. M., Fritsche, A., Nijpels, G., Van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N., Van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., MacHicao, F. & 14 others, Willemsen, G., Heine, R. J., Kramer, M. H., Holst, Jens Juul, De Koning, E. J., Häring, H. U., Pedersen, O., Groop, L., De Geus, E. J., Slagboom, P. E., Boomsma, D. I., Eekhoff, E. M., Pearson, E. R. & Diamant, M., 1 Feb 2015, In: Diabetes Technology & Therapeutics. 17, p. S131-S133

    Research output: Contribution to journalComment/debateResearchpeer-review

  2. Published

    The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway

    't Hart, L. M., Fritsche, A., Nijpels, G., van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N. A., van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M. C., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., Machicao, F. & 14 others, Willemsen, G., Heine, R. J., Kramer, M., Holst, Jens Juul, de Koning, E. J. P., Häring, H., Pedersen, Oluf Borbye, Groop, L., de Geus, E. J. C., Slagboom, P. E., Boomsma, D. I., Eekhoff, E. M. W., Pearson, E. R. & Diamant, M., 14 May 2013, In: Diabetes. 62, 9, p. 3275-3281 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Birthweight, Childhood Body Mass Index, Height and Growth, and Risk of Polycystic Ovary Syndrome

    Aarestrup, J., Pedersen, D. C., Thomas, P. E., Glintborg, D., Holm, Jens-Christian, Bjerregaard, L. G. & Baker, J. L., 2021, In: Obesity Facts. 14, 3, p. 283-290 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Birthweight and risk of thyroid cancer and its histological types: A large cohort study

    Aarestrup, J., Kitahara, C. M. & Baker, J. L., 2019, In: Cancer Epidemiology. 62, 101564.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Birth weight, childhood body mass index and height and risks of endometriosis and adenomyosis

    Aarestrup, J., Jensen, B. W., Ulrich, L. G., Hartwell, D., Trabert, B. & Baker, J. L., 2020, In: Annals of Human Biology. 47, 2, p. 173-180

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Childhood Overweight, Tallness, and Growth Increase Risks of Ovarian Cancer

    Aarestrup, J., Trabert, B., Ulrich, L. G., Wentzensen, N., Sørensen, Thorkild I.A. & Baker, J. L., 2019, In: Cancer Epidemiology, Biomarkers & Prevention. 28, 1, p. 183-188

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Birthweight, childhood overweight, height and growth and adult cancer risks: a review of studies using the Copenhagen School Health Records Register

    Aarestrup, J., Bjerregaard, L. G., Meyle, K. D., Pedersen, D. C., Gjaerde, L. K., Jensen, B. W. & Baker, J. L., 2020, In: International Journal of Obesity. p. 1546-1560

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Genetic Determinants of Weight Loss After Bariatric Surgery

    Aasbrenn, M., Schnurr, T. M., Have, C. T., Svendstrup, M., Hansen, D. L., Worm, Dorte, Balslev-Harder, M., Hollensted, M., Grarup, Niels, Burgdorf, K. S., drb459, drb459, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A., Fenger, M., Madsbad, Sten & Hansen, Torben, 2019, In: Obesity Surgery. 29, 8, p. 2554-2561 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Genetic markers of abdominal obesity and weight loss after gastric bypass surgery

    Aasbrenn, M., Svendstrup, M., Schnurr, T. M., Hansen, D. L., Worm, Dorte, Balslev-Harder, M., Grarup, Niels, Burgdorf, Kristoffer Sølvsten, drb459, drb459, Pedersen, Oluf Borbye, Ängquist, Lars, Fenger, M., Sørensen, Thorkild I.A., Madsbad, Sten & Hansen, Torben, 2021, In: PLoS ONE. 16, 5, 11 p., 0252525.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The antidepressant-like effect of probiotics and their faecal abundance may be modulated by the cohabiting gut microbiota in rats

    Abildgaard, A., Kern, T., Pedersen, Oluf Borbye, Hansen, Torben, Wegener, G. & Lund, S., 2019, In: European Neuropsychopharmacology. 29, 1, p. 98-110

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A diet-induced gut microbiota component and related plasma metabolites are associated with depressive-like behaviour in rats

    Abildgaard, A., Kern, T., Pedersen, Oluf Borbye, Hansen, Torben, Lund, S. & Wegener, G., 2021, In: European Neuropsychopharmacology. 43, p. 10-21

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Levels and Changes in Childhood Body Mass Index in Relation to Risk of Atrial Fibrillation and Atrial Flutter in Adulthood

    Adelborg, K., Ängquist, Lars, Ording, A., Gjærde, L. K., Bjerregaard, L. G., Sørensen, H. T., Sørensen, Thorkild I.A. & Baker, J. L., 2019, In: American Journal of Epidemiology. 188, 4, p. 684-693 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Genetic variants associated with syncope implicate neural and autonomic processes

    Aegisdottir, H. M., Thorolfsdottir, R. B., Sveinbjornsson, G., Stefansson, O. A., Gunnarsson, B., Tragante, V., Thorleifsson, G., Stefansdottir, L., Thorgeirsson, T. E., Ferkingstad, E., Sulem, P., Norddahl, G., Rutsdottir, G., Banasik, K., Christensen, A. H., Mikkelsen, C., Pedersen, O. B., Brunak, S., Bruun, M. T., Erikstrup, C. & 26 others, Jacobsen, R. L., Nielsen, K. R., Sorensen, E., Frigge, M. L., Hjorleifsson, K. E., Ivarsdottir, E., Helgadottir, A., Gretarsdottir, S., Steinthorsdottir, V., Oddsson, A., Eggertsson, H. P., Halldorsson, G. H., Jones, D. A., Anderson, J. L., Knowlton, K. U., Nadauld, L. D., DBDS Genomic Consortium, D. B. D. S. G. C., Haraldsson, M., Thorgeirsson, G., Bundgård, Henning, Arnar, D. O., Thorsteinsdottir, U., Gudbjartsson, D. F., Ostrowsk, S. R., Holm, H. & Stefansson, K., 2023, In: European Heart Journal. 44, 12, p. 1070–1080 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Carriers of a VEGFA enhancer polymorphism selectively binding CHOP/DDIT3 are predisposed to increased circulating levels of thyroid-stimulating hormone

    Ahluwalia, Tarun Veer Singh, Troelsen, J. T., Balslev-Harder, M., Bork-Jensen, J., Thuesen, B. H., Cerqueira, C., Linneberg, Allan René, Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben & Dalgaard, L. T., Mar 2017, In: Journal of Medical Genetics. 54, 3, p. 166-175 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes

    Ahluwalia, Tarun Veer Singh, Allin, K. H., Sandholt, C. H., Sparsø, T. H., Jørgensen, M. E., Rowe, M., Christensen, C., Brandslund, I., Lauritzen, T., Linneberg, Allan René, Husemoen, L., Jørgensen, T., Hansen, Torben, Grarup, Niels & Pedersen, Oluf Borbye, Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E664-71

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

    Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Agerbo, E., Gern, J. E., Lemanske, R. F., Ober, C., Pedersen, A. G., Bisgaard, H. & Bønnelykke, Klaus, 2020, In: Nature Communications. 11, 12 p., 6398.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria

    Ahluwalia, T. S., Schulz, C-A., Waage, J., Skaaby, T., Sandholm, N., van Zuydam, N., Charmet, R., Bork-Jensen, J., Almgren, P., Thuesen, B. H., Bedin, M., Brandslund, I., Christensen, C. K., Linneberg, A., Ahlqvist, E., Groop, P-H., Hadjadj, S., Tregouet, D-A., Jorgensen, M. E., Grarup, N. & 9 others, Pedersen, Oluf Borbye, Simons, M., Groop, L., Orho-Melander, M., McCarthy, M. I., Melander, O., Rossing, Peter, Kilpeläinen, Tuomas O. & Hansen, Torben, 2019, In: Diabetologia. 62, 2, p. 292-305

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Gene x Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry

    Ahmad, S., Rukh, G., Varga, T. V., Ali, A., Kurbasic, A., Shungin, D., Ericson, U., Koivula, R. W., Chu, A. Y., Rose, L. M., Ganna, A., Qi, Q., Stancakova, A., Sandholt, C. H., Elks, C. E., Curhan, G., Jensen, M. K., Tamimi, R. M., Allin, K. H., Jorgensen, T. & 26 others, Brage, S., Langenberg, C., Aadahl, Mette, Grarup, Niels, Linneberg, Allan René, Pare, G., Magnusson, P. K. E., Pedersen, N. L., Boehnke, M., Hamsten, A., Mohlke, K. L., Pasquale, L. T., Pedersen, Oluf Borbye, Scott, R. A., Ridker, P. M., Ingelsson, E., Laakso, M., Hansen, Torben, Qi, L., Wareham, N. J., Chasman, D. I., Hallmans, G., Hu, F. B., Renstrom, F., Orho-Melander, M. & Franks, P. W., Jul 2013, In: PLOS Genetics. 9, 7

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry

    Ahmad, S., Rukh, G., Varga, T. V., Ali, A., Kurbasic, A., Shungin, D., Ericson, U., Koivula, R. W., Chu, A. Y., Rose, L. M., Ganna, A., Qi, Q., Stančáková, A., Sandholt, C. H., Elks, C. E., Curhan, G., Jensen, M. K., Tamimi, R. M., Allin, K. H., Jørgensen, T. & 27 others, Brage, S., Langenberg, C., Aadahl, M., Grarup, Niels, Linneberg, Allan René, Paré, G., Magnusson, P. K. E., Pedersen, N. L., Boehnke, M., Hamsten, A., Mohlke, K. L., Pasquale, L. T., Pedersen, Oluf Borbye, Scott, R. A., Ridker, P. M., Ingelsson, E., Laakso, M., Hansen, Torben, Qi, L., Wareham, N. J., Chasman, D. I., Hallmans, G., Hu, F. B., Renström, F., Orho-Melander, M., Franks, P. W. & InterAct Consortium, I. C., Jul 2013, In: P L o S Genetics (Online). 9, 7, p. e1003607

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Identification of novel homozygous variants in FOXE3 and AP4M1 underlying congenital syndromic anophthalmia and microphthalmia

    Akbar, W., Ullah, A., Haider, N., Suleman, Sufyan, Khan, F. U., Shah, A. A., Sikandar, M. A., Basit, S. & Ahmad, W., 2024, In: Journal of Gene Medicine. 26, 1, 10 p., e3601.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes

    Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T. H., Tian, G., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T. S., Li, Q., Nie, C., Wu, R., Skotte, L., Morris, A. P., Ladenvall, C., Cauchi, S., Stancáková, A., Andersen, G., Astrup, A., Banasik, K. & 86 others, Bennett, A. J., Bolund, L., Charpentier, G., Chen, Y., Dekker, J. M., Doney, A. S. F., Dorkhan, M., Forsen, T., Frayling, T. M., Groves, C. J., Gui, Y., Hallmans, G., Hattersley, A. T., He, K., Hitman, G. A., Holmkvist, J., Huang, S., Jiang, H., Jin, X., Justesen, Johanne Marie, Kristiansen, Karsten, Kuusisto, J., Lajer, M., Lantieri, O., Li, W., Liang, H., Liao, Q., Liu, X., Ma, T., Ma, X., Manijak, M. P., Marre, M., Mokrosinski, J., Morris, A. D., Mu, B., Nielsen, A. A., Nijpels, G., Nilsson, P., Palmer, C. N. A., Rayner, N. W., Renström, F., Ribel-Madsen, R., Robertson, N., Rolandsson, O., Rossing, P., Schwartz, Thue W., Slagboom, P. E., Sterner, M., Tang, M., Tarnow, L., Tuomi, T., Van't Riet, E., van Leeuwen, N., V Varga, Tibor, Vestmar, M. A., Walker, M., Wang, B., Wang, Y., Wu, H., Xi, F., Yengo, L., Yu, C., Zhang, X., Zhang, J., Zhang, Q., Zhang, W., Zheng, H., Zhou, Y., Altshuler, D., 't Hart, L. M., Franks, P. W., Balkau, B., Froguel, P., McCarthy, M. I., Laakso, M., Groop, L., Christensen, C., Brandslund, I., Lauritzen, T., Witte, D. R., Linneberg, A., Jørgensen, T., Hansen, Torben, Wang, J., Nielsen, Rasmus & Pedersen, Oluf Borbye, 2013, In: Diabetologia. 56, 2, p. 298-310 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models: [with Author Correction]

    Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., Brasas, V., Webel, H., Benros, M. E., Pedersen, A. G., Chmura, P. J., Jacobsen, U. P., Mari, A., Koivula, R., Mahajan, A., Vinuela, A. & 31 others, Tajes, J. F., Sharma, S., Haid, M., Hong, M., Musholt, P. B., De Masi, F., Vogt, J., Pedersen, H. K., Gudmundsdottir, V., Jones, A., Kennedy, G., Bell, J., Thomas, E. L., Frost, G., Thomsen, Henrik S., Hansen, E., Hansen, T. H., drb459, drb459, Muilwijk, M., Blom, M. T., 't Hart, L. M., Pattou, F., Raverdy, V., Brage, S., Ridderstråle, M., Pedersen, Oluf Borbye, Hansen, Torben, Banasik, Karina, Rasmussen, Simon, Brunak, Søren & IMI-DIRECT consortium, I. C., 2023, In: Nature Biotechnology. 41, 3, p. 399–408 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Genetic determinants of serum vitamin B12 and their relation to body mass index

    Allin, K. H., Friedrich, N., Pietzner, M., Grarup, Niels, Thuesen, B. H., Linneberg, Allan René, Pisinger, C., Hansen, Torben, Pedersen, Oluf Borbye & Sandholt, C. H., Feb 2017, In: European Journal of Epidemiology. 32, 2, p. 125–134

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    MECHANISMS IN ENDOCRINOLOGY: Gut microbiota in patients with type 2 diabetes mellitus

    Allin, K. H., Nielsen, T. & Pedersen, Oluf Borbye, 2015, In: European Journal of Endocrinology. 172, 4, p. R167-R177 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    Genomet og diabetes

    Allin, K. H., Hansen, Torben & Pedersen, Oluf Borbye, 10 Nov 2014, In: Ugeskrift for Laeger. 176, 23, p. 2176-2179 V06140337.

    Research output: Contribution to journalJournal articleResearchpeer-review

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