- 2016
- Published
Effects of a Family-Based Childhood Obesity Treatment Program on Parental Weight Status
Trier, C., Dahl, M., Stjernholm, T., Nielsen, T. R. H., Bøjsøe, C., Fonvig, C. E., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2016, In: P L o S One. 11, 8, p. 1-11 11 p., e0161921.Research output: Contribution to journal › Journal article › Research › peer-review
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FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials
Livingstone, K. M., Celis-Morales, C., Papandonatos, G. D., Erar, B., Florez, J. C., Jablonski, K. A., Razquin, C., Marti, A., Heianza, Y., Huang, T., Sacks, F. M., Svendstrup, M., Sui, X., Church, T. S., Jääskeläinen, T., Lindström, J., Tuomilehto, J., Uusitupa, M., Rankinen, T., Saris, W. H. M. & 12 others, , 2016, In: B M J. 354, 11 p., i4707.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic investigations of sudden unexpected deaths in infancy using next-generation sequencing of 100 genes associated with cardiac diseases
Hertz, C. L., Christiansen, S. L., Larsen, M. K., Dahl, M., Ferrero-Miliani, L., Weeke, P. E., Pedersen, Oluf Borbye, Hansen, Torben, Grarup, Niels, Ottesen, G. L., Frank-Hansen, R., Banner, Jytte & Morling, Niels, 2016, In: European Journal of Human Genetics. 24, p. 817–822Research output: Contribution to journal › Journal article › Research › peer-review
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Genetics of Type 2 diabetes: the power of isolated populations
Lepola, Mette Andersen, Pedersen, C. T., Moltke, Ida, Hansen, Torben, Albrechtsen, Anders & Grarup, Niels, 2016, In: Current Diabetes Reports. 16, 7, 9 p., 65.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index
Felix, J. F., Bradfield, J. P., Monnereau, C., van der Valk, R. J. P., Stergiakouli, E., Chesi, A., Gaillard, R., Feenstra, B., Thiering, E., Kreiner-Møller, E., Mahajan, A., Pitkänen, N., Joro, R., Cavadino, A., Huikari, V., Franks, S., Groen-Blokhuis, M. M., Cousminer, D. L., Marsh, J. A., Lehtimäki, T. & 31 others, , 2016, In: Human Molecular Genetics. 25, 2, p. 389-403Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes
Imamura, M., Takahashi, A., Yamauchi, T., Hara, K., Yasuda, K., Grarup, N., Zhao, W., Wang, X., Huerta-Chagoya, A., Hu, C., Moon, S., Long, J., Kwak, S. H., Rasheed, A., Saxena, R., Ma, R. C. W., Okada, Y., Iwata, M., Hosoe, J., Shojima, N. & 43 others, , 2016, In: Nature Communications. 7, 12 p., 10531.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
Kilpeläinen, T. O., Carli, J. F. M., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, Å. K., Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikäinen, L-P., Eriksson, J. & 157 others, , 2016, In: Nature Communications. 7, 14 p., 10494.Research output: Contribution to journal › Journal article › Research › peer-review
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Human gut microbes impact host serum metabolome and insulin sensitivity
Pedersen, H. K., Gudmundsdottir, V., Nielsen, H. B., Hyotylainen, T., Nielsen, T., Jensen, B. A. H., Forslund, K., Hildebrand, F., Prifti, E., Falony, G., Le Chatelier, E., Levenez, F., Doré, J., Mattila, I., Plichta, D. R., Pöhö, P., Hellgren, L. I., Arumugam, M., Sunagawa, S., Vieira-Silva, S. & 14 others, , 2016, In: Nature. 535, 7612, p. 376-381 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of novel genetic determinants of erythrocyte membrane fatty acid composition among Greenlanders
Lepola, Mette Andersen, Jørsboe, E., Sandholt, C. H., Grarup, Niels, Jørgensen, M. E., Færgeman, N. J., Bjerregaard, P., Pedersen, Oluf Borbye, Moltke, Ida, Hansen, Torben & Albrechtsen, Anders, 2016, In: P L o S Genetics. 12, 6, 19 p., e1006119.Research output: Contribution to journal › Journal article › Research › peer-review
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Interactions between genetic variants associated with adiposity traits and soft drinks in relation to longitudinal changes in body weight and waist circumference
Olsen, N. J., Ängquist, Lars, Larsen, S. C., Linneberg, Allan René, Skaaby, T., Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Tjønneland, A., Halkjær, J., Hansen, Torben, Pedersen, Oluf Borbye, Overvad, K., Ahluwalia, T. S., Sørensen, Thorkild I.A. & Heitmann, Berit, 2016, In: American Journal of Clinical Nutrition. 104, 3, p. 816-826 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physiology insights
Watanabe, R. M. & Hansen, Torben, 2016, The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation. Springer, p. 207-221 15 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Plasma alkylresorcinols reflect gluten intake and distinguish between gluten-rich and gluten-poor diets in a population at risk of metabolic syndrome
Lind, M. V., Madsen, M. L., Rumessen, J. J., drb459, drb459, Gøbel, R. J., Hansen, Torben, Lauritzen, Lotte, Pedersen, Oluf Borbye, Kristensen, M. B. & Ross, A. B., 2016, In: Journal of Nutrition. 146, 10, p. 1991-1998 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reference values for serum leptin in healthy non-obese children and adolescents
Lausten-Thomsen, U., Christiansen, M., Louise Hedley, P., Fonvig, C. E., Stjernholm, T., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2016, In: Scandinavian Journal of Clinical & Laboratory Investigation. 76, 7, p. 561-567 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota
Palleja, A., Kashani, A., Allin, K. H., Nielsen, T., Zhang, C., Li, Y., Brach, Thorsten, Liang, S., Feng, Q., Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Burgdorf, Kristoffer Sølvsten, Holst, Jens Juul, Madsbad, Sten, Wang, J., Pedersen, Oluf Borbye, Hansen, Torben & Arumugam, Mani, 2016, In: Genome Medicine. 8, 13 p., 67.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample
Esserlind, A., Christensen, A. F., Steinberg, S., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Werge, Thomas, Hansen, T. F., Husemoen, L. L. N., Linneberg, Allan René, Budtz-Joergensen, Esben, Westergaard, M. L., Stefansson, H. & Olesen, Jes, 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The gut microbiota in type 2 diabetes
Nielsen, T., Allin, K. H. & Pedersen, Oluf Borbye, 1 Jan 2016, The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation. Springer, p. 275-293 19 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide (GIP) is associated with lower LDL but unhealthy fat distribution, independent of insulin: The ADDITION-PRO study
Møller, C. L., Vistisen, D., Færch, K., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Jørgensen, M. E., Torekov, Signe Sørensen & Holst, Jens Juul, Feb 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 2, p. 485– 493 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., Cousminer, D. L., Dastani, Z., Drong, A. W., Esko, T., Evans, D. M., Falchi, M., Feitosa, M. F., Ferreira, T., Hedman, Å. K., Haring, R., Hysi, P. G., Iles, M. M., Justice, A. E., Kanoni, S. & 239 others, , 1 Feb 2016, In: Nature Communications. 7, p. 1-15 15 p., 10495.Research output: Contribution to journal › Journal article › Research › peer-review
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Obesity and Bariatric Surgery Drive Epigenetic Variation of Spermatozoa in Humans
Donkin, I., Versteyhe, S., Ingerslev, L. R., Qian, K., Mechta, Mie, Nordkap, L., Mortensen, B., Appel, E. V. R., Jørgensen, N., Kristiansen, V. B., Hansen, Torben, Workman, C. T., Zierath, Juleen R & Barrès, Romain, 9 Feb 2016, In: Cell Metabolism. 23, 2, p. 369-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Major rapid weight loss induces changes in cardiac repolarization
Vedel-Larsen, E., Iepsen, E. P. W., Lundgren, J., Graff, C., Struijk, J. J., Hansen, Torben, Holst, Jens Juul, Madsbad, Sten, Torekov, Signe Sørensen & Kanters, Jørgen K., 10 Feb 2016, In: Journal of Electrocardiology. 49, 3, p. 467-472 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mendelian randomisation study of the associations of vitamin B12 and folate genetic risk scores with blood pressure and fasting serum lipid levels in three Danish population-based studies
Husemoen, L. L. N., Skaaby, T., Thuesen, B. H., Grarup, Niels, Sandholt, C. H., Hansen, Torben, Pedersen, Oluf Borbye & Linneberg, Allan René, 24 Feb 2016, In: European Journal of Clinical Nutrition. 70, p. 613-619 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insights into metabolic disease from studying genetics in isolated populations: stories from Greece to Greenland
Zeggini, E., Gloyn, A. L. & Hansen, Torben, 18 Mar 2016, In: Diabetologia. 59, 5, p. 938-941 4 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Levels of the inflammation marker YKL-40 in young adults exposed to intrauterine hyperglycemia
Kelstrup, L., Dejgaard, T. F., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Hansen, Torben, drb459, drb459 & Damm, Peter, Apr 2016, In: Diabetes Research and Clinical Practice. 114, p. 50-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prognostic impact of carboxylesterase 1 gene variants in patients with congestive heart failure treated with angiotensin-converting enzyme inhibitors
Nelveg-Kristensen, K. E., Madsen, M. B., Torp-Pedersen, C., Køber, Lars Valeur, Egfjord, Martin, Hansen, Torben, Pedersen, Oluf Borbye, Rasmussen, H. B. & Hansen, Peter Riis, Apr 2016, In: Pharmacogenetics and Genomics. 26, 4, p. 169–177 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
Okbay, A., Baselmans, B. M. L., De Neve, J-E., Turley, P., Nivard, M. G., Fontana, M. A., Meddens, S. F. W., Linnér, R. K., Rietveld, C. A., Derringer, J., Gratten, J., Lee, J. J., Liu, J. Z., de Vlaming, R., Ahluwalia, T. V. S., Buchwald, J., Cavadino, A., Frazier-Wood, A. C., Furlotte, N. A., Garfield, V. & 31 others, , Jun 2016, In: Nature Genetics. 48, 6, p. 624-33 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Estimation of allele frequency and association mapping using next-generation sequencing data
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Change in abdominal obesity after colon cancer surgery – effects of left-sided and right-sided colonic resection
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