Hansen Group

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  1. 2016
  2. Published

    A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

    Scott, R. A., Freitag, D. F., Li, L., Chu, A. Y., Surendran, P., Young, R., Grarup, N., Stancakova, A., Chen, Y., Varga, T. V., Yaghootkar, H., Luan, J., Zhao, J. H., Willems, S. M., Wessel, J., Wang, S., Maruthur, N., Michailidou, K., Pirie, A., van der Lee, S. J. & 119 others, Gillson, C., Al Olama, A. A., Amouyel, P., Arriola, L., Arveiler, D., Aviles-Olmos, I., Balkau, B., Barricarte, A., Barroso, I., Garcia, S. B., Bis, J. C., Blankenberg, S., Boehnke, M., Boeing, H., Boerwinkle, E., Borecki, I. B., Bork-Jensen, J., Bowden, S., Caldas, C., Caslake, M., Cupples, L. A., Cruchaga, C., Czajkowski, J., den Hoed, M., Dunn, J. A., Earl, H. M., Ehret, G. B., Ferrannini, E., Ferrieres, J., Foltynie, T., Ford, I., Forouhi, N. G., Gianfagna, F., Gonzalez, C., Grioni, S., Hiller, L., Jansson, J., Jørgensen, M. E., Jukema, J. W., Kaaks, R., Kee, F., Kerrison, N. D., Key, T. J., Kontto, J., Kote-Jarai, Z., Kraja, A. T., Kuulasmaa, K., Kuusisto, J., Linneberg, Allan René, Liu, C., Marenne, G., Mohlke, K. L., Morris, A. P., Muir, K., Mueller-Nurasyid, M., Munroe, P. B., Navarro, C., Nielsen, S. F., Nilsson, P. M., Nordestgaard, B. G., Packard, C. J., Palli, D., Panico, S., Peloso, G. M., Perola, M., Peters, A., Poole, C. J., Quiros, J. R., Rolandsson, O., Sacerdote, C., Salomaa, V., Sanchez, M., Sattar, N., Sharp, S. J., Sims, R., Slimani, N., Smith, J. A., Thompson, D. J., Trompet, S., Tumino, R., van der A, D. L., van der Schouw, Y. T., Virtamo, J., Walker, M., Walter, K., Abraham, J. E., Amundadottir, L. T., Aponte, J. L., Butterworth, A., Dupuis, J., Easton, D. F., Eeles, R. A., Erdmann, J., Franks, P. W., Frayling, T. M., Hansen, Torben, Howson, J. M. M., Jørgensen, T., Kooner, J., Laakso, M., Langenberg, C., McCarthy, M. I., Pankow, J. S., Pedersen, Oluf Borbye, Riboli, E., Rotter, J. I., Saleheen, D., Samani, N. J., Schunkert, H., Vollenweider, P., O'Rahilly, S., Deloukas, P., Danesh, J., Goodarzi, M. O., Kathiresan, S., Meigs, J. B., Ehm, M. G., Wareham, N. J. & Waterworth, D. M., 1 Jun 2016, In: Science Translational Medicine. 8, 341, 13 p., 341ra76.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

    Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A. B., Norddahl, G. L., Helgadottir, A., Magnusdottir, A., Jonasdottir, A., Gretarsdottir, S., Jonsdottir, I., Steinthorsdottir, V., Rafnar, T., Swinkels, D. W., Galesloot, T. E., Grarup, N., Jørgensen, T., Vestergaard, H., Hansen, T., Lauritzen, T. & 34 others, Linneberg, Allan René, Friedrich, N., Krarup, N. T., Fenger, M., Abildgaard, U., Hansen, Peter Riis, Galløe, A. M., Braund, P. S., Nelson, C. P., Hall, A. S., Williams, M. J. A., van Rij, A. M., Jones, G. T., Patel, R. S., Levey, A. I., Hayek, S., Shah, S. H., Reilly, M., Eyjolfsson, G. I., Sigurdardottir, O., Olafsson, I., Kiemeney, L. A., Quyyumi, A. A., Rader, D. J., Kraus, W. E., Samani, N. J., Pedersen, Oluf Borbye, Thorgeirsson, G., Masson, G., Holm, H., Gudbjartsson, D., Sulem, P., Thorsteinsdottir, U. & Stefansson, K., 2 Jun 2016, In: New England Journal of Medicine. 374, 22, p. 2131-2141 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

    Chami, N., Chen, M-H., Slater, A. J., Eicher, J. D., Evangelou, E., Tajuddin, S. M., Love-Gregory, L., Kacprowski, T., Schick, U. M., Nomura, A., Giri, A., Lessard, S., Brody, J. A., Schurmann, C., Pankratz, N., Yanek, L. R., Manichaikul, A., Pazoki, R., Mihailov, E., Hill, W. D. & 93 others, Raffield, L. M., Burt, A., Bartz, T. M., Becker, D. M., Becker, L. C., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., O'Donoghue, M. L., Crosslin, D. R., de Denus, S., Dubé, M., Elliott, P., Engström, G., Evans, M. K., Floyd, J. S., Fornage, M., Gao, H., Greinacher, A., Gudnason, V., Hansen, Torben, Harris, T. B., Hayward, C., Hernesniemi, J., Highland, H. M., Hirschhorn, J. N., Hofman, A., Irvin, M. R., Kähönen, M., Lange, E., Launer, L. J., Lehtimäki, T., Li, J., Liewald, D. C. M., Linneberg, Allan René, Liu, Y., Lu, Y., Lyytikäinen, L., Mägi, R., Mathias, R. A., Melander, O., Metspalu, A., Mononen, N., Nalls, M. A., Nickerson, D. A., Nikus, K., O'Donnell, C. J., Orho-Melander, M., Pedersen, Oluf Borbye, Petersmann, A., Polfus, L., Psaty, B. M., Raitakari, O. T., Raitoharju, E., Richard, M., Rice, K. M., Rivadeneira, F., Rotter, J. I., Schmidt, F., Smith, A. V., Starr, J. M., Taylor, K. D., Teumer, A., Thuesen, B. H., Torstenson, E. S., Tracy, R. P., Tzoulaki, I., Zakai, N. A., Vacchi-Suzzi, C., van Duijn, C. M., van Rooij, F. J. A., Cushman, M., Deary, I. J., Velez Edwards, D. R., Vergnaud, A., Wallentin, L., Waterworth, D. M., White, H. D., Wilson, J. G., Zonderman, A. B., Kathiresan, S., Grarup, Niels, Esko, T., Loos, R. J. F., Lange, L. A., Faraday, N., Abumrad, N. A., Edwards, T. L., Ganesh, S. K., Auer, P. L., Johnson, A. D., Reiner, A. P. & Lettre, G., 7 Jul 2016, In: American Journal of Human Genetics. 99, 1, p. 8-21 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The Role of the Gut Microbiota in Childhood Obesity

    Pihl, A. F., Fonvig, C. E., Stjernholm, T., Hansen, Torben, Pedersen, Oluf Borbye & Holm, Jens-Christian, 25 Jul 2016, In: Childhood Obesity. 12, 4, p. 292-299 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Genetic risk scores link body fat distribution with specific cardiometabolic profiles

    Svendstrup, M., Sandholt, C. H., Andersson Galijatovic, E. A., Linneberg, Allan René, Jørgensen, T., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Grarup, Niels, Hansen, Torben & drb459, drb459, Aug 2016, In: Obesity. 24, 8, p. 1778-1785 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits

    CHARGE Consortium Hematology Working Group, C. C. H. W. G., Aug 2016, In: Nature Genetics. 48, 8, p. 867-876 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The genetic architecture of type 2 diabetes

    Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Fernandez Tajes, J., Highland, H. M. & 281 others, Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, Niels, Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B., Kim, Y., Kim, Y. J., Kwon, M., Lee, J., Lee, S., Lin, K., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stancáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., van der Schouw, Y. T., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, Johanne Marie, Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, Allan René, Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., Hrabé de Angelis, M., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, Torben, Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, Oluf Borbye, Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Burtt, N. P., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Florez, J. C., Scott, L. J., Morris, A. P., Kang, H. M., Boehnke, M., Altshuler, D. & McCarthy, M. I., 4 Aug 2016, In: Nature. 536, 7614, p. 41-47 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Insulin Resistance is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation

    Faerch, K., Vistisen, D., Pacini, G., Torekov, Signe Sørensen, Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Jørgensen, M. E., Ahrén, B. & Holst, Jens Juul, 8 Aug 2016, In: Diabetes. 65, 11, p. 3473-3481 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Transcriptional interactions suggest niche segregation among microorganisms in the human gut

    Plichta, D. R., Juncker, A. S., Bertalan, M., Rettedal, E., Gautier, L., Varela, E., Manichanh, C., Fouqueray, C., Levenez, F., Nielsen, T., Doré, J., Machado, A. M. D., de Evgrafov, M. C. R., Hansen, T., Jørgensen, T., Bork, P., Guarner, F., Pedersen, O., Metagenomics of the Human Intestinal Tract (MetaHIT) Consortium, Sommer, M. O. A. & 4 others, Ehrlich, S. D., Sicheritz-Pontén, T., Brunak, Søren & Nielsen, H. B., 26 Aug 2016, In: Nature Microbiology. 1, p. 1-6 6 p., 16152.

    Research output: Contribution to journal › Letter › Research › peer-review

  11. Published

    Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population

    Vestmar, M. A., Galijatovic, E. A. A., Christensen, C. R., Pedersen, M. H., Glümer, C., Linneberg, Allan René, Witte, D. R., Jørgensen, M. E., Christensen, C., Brandslund, I., Lauritzen, T., Pedersen, Oluf Borbye, Holst, Birgitte, Grarup, Niels, Schwartz, Thue W. & Hansen, Torben, Sep 2016, In: Journal of Medical Genetics. 53, 9, p. 616-23 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

    Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P., Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A., Harakalova, M. & 32 others, Mihailov, E., Liu, C., Kraja, A. T., Nielsen, S. F., Rasheed, A., Samuel, M., Zhao, W., Bonnycastle, L. L., Jackson, A. U., Narisu, N., Swift, A. J., Southam, L., Marten, J., Huyghe, J. R., Stančáková, A., Fava, C., Ohlsson, T., Matchan, A., Stirrups, K. E., Bork-Jensen, J., Gjesing, A. P., Kontto, J., Perola, M., Shaw-Hawkins, S., Havulinna, A. S., Husemoen, L. L., Linneberg, Allan René, Hansen, Torben, Pedersen, Oluf Borbye, Nordestgaard, Børge, CHARGE-Heart Failure Consortium, C. F. C. & V Varga, Tibor, 12 Sep 2016, In: Nature Genetics. 48, 10, p. 1151-1161 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Genome-wide associations for birth weight and correlations with adult disease

    Horikoshi, M., Beaumont, R. N., Day, F. R., Warrington, N. M., Kooijman, M. N., Fernandez-Tajes, J., Feenstra, B., van Zuydam, N. R., Gaulton, K. J., Grarup, N., Bradfield, J. P., Strachan, D. P., Li-Gao, R., Ahluwalia, T. V. S., Kreiner, E., Rueedi, R., Lyytikäinen, L-P., Cousminer, D. L., Wu, Y., Thiering, E. & 31 others, Wang, C. A., Have, C. T., Hottenga, J., Vilor-Tejedor, N., Joshi, P. K., Boh, E. T. H., Ntalla, I., Pitkänen, N., Mahajan, A., van Leeuwen, E. M., Joro, R., Lagou, V., Nodzenski, M., Diver, L. A., Zondervan, K. T., Bustamante, M., Marques-Vidal, P., Mercader, J. M., Appel, E. V. R., Waage, J., Sørensen, Thorkild I.A., Melbye, M., Kadarmideen, H. N., Holm, Jens-Christian, Hansen, Torben, Bønnelykke, Klaus, Bisgaard, H., Pisinger, C., Pedersen, Oluf Borbye, Vaag, Allan & CHARGE Consortium Hematology Working Group, C. C. H. W. G., 28 Sep 2016, In: Nature. 538, p. 248-252 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  14. Published

    Genome-wide association study of the modified Stumvoll Insulin Sensitivity Index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci

    Walford, G. A., Gustafsson, S., Rybin, D., Stančáková, A., Chen, H., Liu, C-T., Hong, J., Jensen, R. A., Rice, K., Morris, A. P., Mägi, R., Tönjes, A., Prokopenko, I., Kleber, M. E., Delgado, G., Silbernagel, G., Jackson, A. U., Appel, E. V., Grarup, N., Lewis, J. P. & 59 others, Montasser, M. E., Landenvall, C., Staiger, H., Luan, J., Frayling, T. M., Weedon, M. N., Xie, W., Morcillo, S., Martínez-Larrad, M. T., Biggs, M. L., Ida Chen, Y., Corbaton-Anchuelo, A., Faerch, K., Zumaquero, J. M., Goodarzi, M. O., Kizer, J., Koistinen, H. A., Leong, A., Lind, L., Lindgren, C., Machicao, F., Manning, A. K., Martín-Núñez, G. M., Rojo-Martínez, G., Rotter, J. I., Siscovick, D. S., Zmuda, J. M., Zhang, Z., Serrano-Rios, M., Smith, U., Soriguer, F., Hansen, Torben, Jørgensen, T., Linnenberg, A., Pedersen, Oluf Borbye, Walker, M., Langenberg, C., Scott, R. A., Wareham, N. J., Fritsche, A., Häring, H., Stefan, N., Groop, L., O'Connell, J. R., Boehnke, M., Bergman, R. N., Collins, F. S., Mohlke, K. L., Tuomilehto, J., März, W., Kovacs, P., Stumvoll, M., Psaty, B. M., Kuusisto, J., Laakso, M., Meigs, J. B., Dupuis, J., Ingelsson, E. & Florez, J. C., Oct 2016, In: Diabetes. 65, 10, p. 3200-3211 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Vejle diabetes Biobank: A resource for studies of the etiologies of diabetes and its comorbidities

    Petersen, E. R. B., Nielsen, A. A., Christensen, H., Hansen, Torben, Pedersen, Oluf Borbye, Christensen, C. K. & Brandslund, I., 21 Oct 2016, In: Clinical Epidemiology. 8, p. 393-413 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology

    Schnurr, T. M., Gjesing, A. M. P., Sandholt, C. H., Jonsson, Anna Elisabet, Mahendran, Y., Have, C. T., Ekstrøm, Claus Thorn, Bjerregaard, A., Brage, S., Witte, D., Jørgensen, M. E., Aadahl, Mette, Thuesen, B. H., Linneberg, Allan René, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye, Grarup, Niels, Kilpeläinen, Tuomas O. & Hansen, Torben, 15 Nov 2016, In: P L o S One. 11, 11, 14 p., e0166738.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

    Ried, J. S., Jeff M, J., Chu, A. Y., Bragg-Gresham, J. L., van Dongen, J., Huffman, J. E., Ahluwalia, T. V. S., Cadby, G., Eklund, N., Eriksson, J., Esko, T., Feitosa, M. F., Goel, A., Gorski, M., Hayward, C., Heard-Costa, N. L., Jackson, A. U., Jokinen, E., Kanoni, S., Kristiansson, K. & 256 others, Kutalik, Z., Lahti, J., Luan, J., Mägi, R., Mahajan, A., Mangino, M., Medina-Gomez, C., Monda, K. L., Nolte, I. M., Pérusse, L., Prokopenko, I., Qi, L., Rose, L. M., Salvi, E., Smith, M. T., Snieder, H., Stančáková, A., Ju Sung, Y., Tachmazidou, I., Teumer, A., Thorleifsson, G., van der Harst, P., Walker, R. W., Wang, S. R., Wild, S. H., Willems, S. M., Wong, A., Zhang, W., Albrecht, E., Couto Alves, A., Bakker, S. J. L., Barlassina, C., Bartz, T. M., Beilby, J., Bellis, C., Bergman, R. N., Bergmann, S., Blangero, J., Blüher, M., Boerwinkle, E., Bonnycastle, L. L., Bornstein, S. R., Bruinenberg, M., Campbell, H., Chen, Y. I., Chiang, C. W. K., Chines, P. S., Collins, F. S., Cucca, F., Cupples, L. A., D'Avila, F., de Geus, E. J. C., Dedoussis, G., Dimitriou, M., Döring, A., Eriksson, J. G., Farmaki, A., Farrall, M., Ferreira, T., Fischer, K., Forouhi, N. G., Friedrich, N., Gjesing, A. M. P., Glorioso, N., Graff, M., Grallert, H., Grarup, Niels, Gräßler, J., Grewal, J., Hamsten, A., Harder, M. N., Hartman, C. A., Hassinen, M., Hastie, N., Hattersley, A. T., Havulinna, A. S., Heliövaara, M., Hillege, H., Hofman, A., Holmen, O., Homuth, G., Hottenga, J., Hui, J., Husemoen, L. L., Hysi, P. G., Isaacs, A., Ittermann, T., Jalilzadeh, S., James, A. L., Jørgensen, T., Jousilahti, P., Jula, A., Justesen, Johanne Marie, Justice, A. E., Kähönen, M., Karaleftheri, M., Tee Khaw, K., Keinanen-Kiukaanniemi, S. M., Kinnunen, L., Knekt, P. B., Koistinen, H. A., Kolcic, I., Kooner, I. K., Koskinen, S., Kovacs, P., Kyriakou, T., Laitinen, T., Langenberg, C., Lewin, A. M., Lichtner, P., Lindgren, C. M., Lindström, J., Linneberg, Allan René, Lorbeer, R., Lorentzon, M., Luben, R., Lyssenko, V., Männistö, S., Manunta, P., Leach, I. M., McArdle, W. L., Mcknight, B., Mohlke, K. L., Mihailov, E., Milani, L., Mills, R., Montasser, M. E., Morris, A. P., Müller, G., Musk, A. W., Narisu, N., Ong, K. K., Oostra, B. A., Osmond, C., Palotie, A., Pankow, J. S., Paternoster, L., Penninx, B. W., Pichler, I., Pilia, M. G., Polašek, O., Pramstaller, P. P., Raitakari, O. T., Rankinen, T., Rao, D. C., Rayner, N. W., Ribel-Madsen, R., Rice, T. K., Richards, M., Ridker, P. M., Rivadeneira, F., Ryan, K. A., Sanna, S., Sarzynski, M. A., Scholtens, S., Scott, R. A., Sebert, S., Southam, L., Sparsø, T. H., Steinthorsdottir, V., Stirrups, K., Stolk, R. P., Strauch, K., Stringham, H. M., Swertz, M. A., Swift, A. J., Tönjes, A., Tsafantakis, E., van der Most, P. J., Van Vliet-Ostaptchouk, J. V., Vandenput, L., Vartiainen, E., Venturini, C., Verweij, N., Viikari, J. S., Vitart, V., Vohl, M., Vonk, J. M., Waeber, G., Widén, E., Willemsen, G., Wilsgaard, T., Winkler, T. W., Wright, A. F., Yerges-Armstrong, L. M., Hua Zhao, J., Carola Zillikens, M., Boomsma, D. I., Bouchard, C., Chambers, J. C., Chasman, D. I., Cusi, D., Gansevoort, R. T., Gieger, C., Hansen, Torben, Hicks, A. A., Hu, F., Hveem, K., Jarvelin, M., Kajantie, E., Kooner, J. S., Kuh, D., Kuusisto, J., Laakso, M., Lakka, T. A., Lehtimäki, T., Metspalu, A., Njølstad, I., Ohlsson, C., Oldehinkel, A. J., Palmer, L. J., Pedersen, Oluf Borbye, Perola, M., Peters, A., Psaty, B. M., Puolijoki, H., Rauramaa, R., Rudan, I., Salomaa, V., Schwarz, Peter, Shudiner, A. R., Smit, J. H., Sørensen, Thorkild I.A., Spector, T. D., Stefansson, K., Stumvoll, M., Tremblay, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., Völker, U., Vollenweider, P., Wareham, N. J., Watkins, H., Wilson, J. F., Zeggini, E., Abecasis, G. R., Boehnke, M., Borecki, I. B., Deloukas, P., van Duijn, C. M., Fox, C., Groop, L. C., Heid, I. M., Hunter, D. J., Kaplan, R. C., McCarthy, M. I., North, K. E., O'Connell, J. R., Schlessinger, D., Thorsteinsdottir, U., Strachan, D. P., Frayling, T., Hirschhorn, J. N., Müller-Nurasyid, M. & Loos, R. J. F., 23 Nov 2016, In: Nature Communications. 7, 11 p., 13357.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    (1)H-MRS measured ectopic fat in liver and muscle is associated with the metabolic syndrome in Danish girls but not in boys with overweight and obesity

    Nissen, A., Fonvig, C. E., Chabanova, E., Bøjsøe, C., Trier, C., Pedersen, Oluf Borbye, Hansen, Torben, Thomsen, Henrik S. & Holm, Jens-Christian, Dec 2016, In: Obesity Science & Practice. 2, 4, p. 376-384 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Increasing insulin resistance accentuates the effect of triglyceride-associated loci on serum triglycerides during 5 years

    Justesen, Johanne Marie, Andersson, E. A., Allin, K. H., Sandholt, C. H., Jørgensen, T., Linneberg, Allan René, Jørgensen, M. E., Hansen, Torben, Pedersen, Oluf Borbye & Grarup, Niels, Dec 2016, In: Journal of Lipid Research. 57, 12, p. 2193-2199 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Weight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels

    pjx571, pjx571, Iepsen, E. P. W., Galijatovic, E. A. A., Mahendran, Y., Lundgren, J. R., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, Dec 2016, In: Metabolomics. 12, 12, p. 1-9 9 p., 181.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. 2017
  22. Published

    A Genome-Wide Association Study of IVGTT-Based Measures of First Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

    Wood, A. R., Jonsson, A., Jackson, A. U., Wang, T-N., van Leewen, N., Palmer, N. D., Kobes, S., Deelen, J., Boquete-Vilarino, L., Paananen, J., Stančáková, A., Boomsma, D. I., de Geus, E. J., Eekhoff, E. M., Fritsche, A., Kramer, M., Nijpels, G., Simonis-Bik, A. M. C., van Haeften, T. W., Mahajan, A. & 31 others, Boehnke, M., Bergman, R. N., Tuomilehto, J., Collins, F. S., Mohlke, K. L., Banasik, Karina, Groves, C. J., McCarthy, M. I., Pearson, E. R., Natali, A., Mari, A., Buchanan, T. A., Taylor, K. D., Xiang, A. H., Gjesing, A. P., Grarup, Niels, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye, Chen, Y., Laakso, M., Norris, J. M., Smith, U., Wagenknecht, L. E., Baier, L., Bowden, D. W., Hansen, Torben, Walker, M., Watanabe, R. M., 't Hart, L. M., Hanson, R. L. & Frayling, T. M., 2017, In: Diabetes. 66, 8, p. 2296-2309

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents

    Nielsen, T. R. H., Appel, E. V. R., Svendstrup, M., Ohrt, J. D., Dahl, M., Fonvig, C. E., Hollensted, M., Have, C. T., Kadarmideen, H. N., Pedersen, Oluf Borbye, Hansen, Torben, Holm, Jens-Christian & Grarup, Niels, 2017, In: PloS one. 12, 3, 16 p., e0174204.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A study of associations between early DHA status and fatty acid desaturase (FADS) SNP and developmental outcomes in children of obese mothers

    Andersen, K. R., Harsløf, L. B. S., Schnurr, T. M., Hansen, Torben, Hellgren, L. I., Michaelsen, Kim F. & Lauritzen, Lotte, 2017, In: The British Journal of Nutrition. 117, 2, p. 278-286 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

    Scott, R. A., Scott, L. J., Mägi, R., Marullo, L., Gaulton, K. J., Kaakinen, M., Pervjakova, N., Pers, T. H., Johnson, A. D., Eicher, J. D., Jackson, A. U., Ferreira, T., Lee, Y., Ma, C., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Van Zuydam, N. R., Mahajan, A., Chen, H. & 155 others, Almgren, P., Voight, B. F., Grallert, H., Müller-Nurasyid, M., Ried, J. S., Rayner, W. N., Robertson, N., Karssen, L. C., van Leeuwen, E. M., Willems, S. M., Fuchsberger, C., Kwan, P., Teslovich, T. M., Chanda, P., Li, M., Lu, Y., Dina, C., Thuillier, D., Yengo, L., Jiang, L., Sparso, T., Kestler, H. A., Chheda, H., Eisele, L., Gustafsson, S., Frånberg, M., Strawbridge, R. J., Benediktsson, R., Hreidarsson, A. B., Kong, A., Sigurðsson, G., Kerrison, N. D., Luan, J., Liang, L., Meitinger, T., Roden, M., Thorand, B., Esko, T., Mihailov, E., Fox, C., Liu, C., Rybin, D., Isomaa, B., Lyssenko, V., Tuomi, T., Couper, D. J., Pankow, J. S., Grarup, Niels, Have, C. T., Jørgensen, M. E., Jørgensen, T., Linneberg, Allan René, Cornelis, M. C., van Dam, R. M., Hunter, D. J., Kraft, P., Sun, Q., Edkins, S., Owen, K. R., Perry, J. R., Wood, A. R., Zeggini, E., Tajes-Fernandes, J., Abecasis, G. R., Bonnycastle, L. L., Chines, P. S., Stringham, H. M., Koistinen, H. A., Kinnunen, L., Sennblad, B., Mühleisen, T. W., Nöthen, M. M., Pechlivanis, S., Baldassarre, D., Gertow, K., Humphries, S. E., Tremoli, E., Klopp, N., Meyer, J., Steinbach, G., Wennauer, R., Eriksson, J. G., Mӓnnistö, S., Peltonen, L., Tikkanen, E., Charpentier, G., Eury, E., Lobbens, S., Gigante, B., Leander, K., McLeod, O., Bottinger, E. P., Gottesman, O., Ruderfer, D., Blüher, M., Kovacs, P., Tonjes, A., Maruthur, N. M., Scapoli, C., Erbel, R., Jöckel, K., Moebus, S., de Faire, U., Hamsten, A., Stumvoll, M., Deloukas, P., Donnelly, P. J., Frayling, T. M., Hattersley, A. T., Ripatti, S., Salomaa, V., Pedersen, N. L., Boehm, B. O., Bergman, R. N., Collins, F. S., Mohlke, K. L., Tuomilehto, J., Hansen, Torben, Pedersen, Oluf Borbye, Barroso, I., Lannfelt, L., Ingelsson, E., Lind, L., Lindgren, C. M., Cauchi, S., Froguel, P., Loos, R. J., Balkau, B., Boeing, H., Franks, P. W., Gurrea, A. B., Palli, D., van der Schouw, Y. T., Altshuler, D., Groop, L. C., Langenberg, C., Wareham, N. J., Sijbrands, E., van Duijn, C. M., Florez, J. C., Meigs, J. B., Boerwinkle, E., Gieger, C., Strauch, K., Metspalu, A., Morris, A. D., Palmer, C. N., Hu, F. B., Thorsteinsdottir, U., Stefansson, K., Dupuis, J., Morris, A. P., Boehnke, M., McCarthy, M. I. & Prokopenko, I., 2017, In: Diabetes. 66, 11, p. 2888-2902

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion

    Skov, L., Schierup, M. H., Danish Pan Genome Consortium, D. P. G. C., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Rasmussen, Simon, Kristiansen, Karsten & Brunak, Søren, 2017, In: PLOS Genetics. 13, 8, p. e1006834

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Archaic adaptive introgression in TBX15/WARS2

    Racimo, Fernando, Gokhman, D., Fumagalli, M., Ko, A., Hansen, Torben, Moltke, Ida, Albrechtsen, Anders, Carmel, L., Huerta-Sánchez, E. & Nielsen, Rasmus, 2017, In: Molecular Biology and Evolution. 34, 3, p. 509-524 16 p., msw283.

    Research output: Contribution to journal › Journal article › Research › peer-review

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