Hansen Group

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  1. 2014
  2. Published

    KCNQ1 Long QT syndrome patients have hyperinsulinemia and symptomatic hypoglycemia

    Torekov, Signe Sørensen, Iepsen, E., Christiansen, M., Linneberg, Allan René, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K. & Hansen, Torben, Apr 2014, In: Diabetes. 63, 4, p. 1315-1325 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

    Flannick, J., Thorleifsson, G., Beer, N. L., Jacobs, S. B. R., Grarup, N., Burtt, N. P., Mahajan, A., Fuchsberger, C., Atzmon, G., Benediktsson, R., Blangero, J., Bowden, D. W., Brandslund, I., Brosnan, J., Burslem, F., Chambers, J., Cho, Y. S., Christensen, C., Douglas, D. A., Duggirala, R. & 31 others, Dymek, Z., Farjoun, Y., Fennell, T., Fontanillas, P., Forsén, T., Gabriel, S., Glaser, B., Gudbjartsson, D. F., Hanis, C., Hansen, Torben, Hreidarsson, A. B., Hveem, K., Ingelsson, E., Isomaa, B., Johansson, S., Jørgensen, T., Jørgensen, M. E., Kathiresan, S., Kong, A., Kooner, J., Kravic, J., Laakso, M., Lee, J., Lind, L., Lindgren, C. M., Linneberg, Allan René, Masson, G., Meitinger, T., Ribel-Madsen, R., Pedersen, Oluf Borbye & Go-T2D Consortium, G. C., Apr 2014, In: Nature Genetics. 46, 4, p. 357-63 7 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  4. Published

    Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients with Maturity Onset Diabetes of the Young - Type 2 and Type 3

    Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 27 Mar 2014, In: Diabetes. 63, 8, p. 2838-44 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes

    Steinthorsdottir, V., Thorleifsson, G., Sulem, P., Helgason, H., Grarup, N., Sigurdsson, A., Helgadottir, H. T., Johannsdottir, H., Magnusson, O. T., Gudjonsson, S. A., Justesen, J. M., Harder, M. N., Jørgensen, M. E., Christensen, C., Brandslund, I., Sandbæk, A., Lauritzen, T., Vestergaard, H., Linneberg, A., Jørgensen, T. & 14 others, Hansen, Torben, Daneshpour, M. S., Fallah, M., Hreidarsson, A. B., Sigurdsson, G., Azizi, F., Benediktsson, R., Masson, G., Helgason, A., Kong, A., Gudbjartsson, D. F., Pedersen, Oluf Borbye, Thorsteinsdottir, U. & Stefansson, K., 26 Jan 2014, In: Nature Genetics. 46, 3, p. 294-300 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification

    Husemoen, L. L. N., Skaaby, T., Jørgensen, T., Thuesen, B. H., Fenger, M., Grarup, Niels, Sandholt, C. H., Hansen, Torben, Pedersen, Oluf Borbye & Linneberg, Allan René, 24 Jan 2014, In: European Journal of Nutrition. 53, 7, p. 1549-59 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A combined analysis of 48 type 2 diabetes genetic risk variants shows no discriminative value to predict time to first prescription of a glucose lowering drug in Danish patients with screen detected type 2 diabetes.

    Hornbak, M., Allin, K. H., Jensen, M. L., Lau, C. J., Witte, D. R., Jørgensen, M. E., Sandbæk, A., Lauritzen, T., Andersson, Åsa, Pedersen, Oluf Borbye & Hansen, Torben, 2014, In: PloS One. 9, 8, 10 p., e104837.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

    Moltke, I., Grarup, N., Jørgensen, M. E., Bjerregaard, P., Treebak, J. T., Fumagalli, M., Korneliussen, T. S., Andersen, M. A., Nielsen, T. S., Krarup, N. T., Gjesing, A. M. P., Zierath, J. R., Linneberg, A., Wu, X., Sun, G., Jin, X., Al-Aama, J., Wang, J., Borch-Johnsen, K., Pedersen, O. & 3 others, Nielsen, R., Albrechtsen, Anders & Hansen, Torben, 2014, In: Nature. 512, 7513, p. 190-193 4 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  9. Published

    An integrated catalog of reference genes in the human gut microbiome

    Li, J., Jia, H., Cai, X., Zhong, H., Feng, Q., Sunagawa, S., Arumugam, M., Kultima, J. R., Prifti, E., Nielsen, T., Juncker, A., Manichanh, C., Chen, B., Zhang, W., Levenez, F., Wang, J., Xu, X., Xiao, L., Liang, S., Zhang, D. & 17 others, Zhang, Z., Chen, W., Zhao, H., Al-Aama, J. Y., Edris, S., Yang, H., Wang, J., Hansen, Torben, Nielsen, H. B., Brunak, S., Kristiansen, Karsten, Guarner, F., Pedersen, Oluf Borbye, Doré, J., Ehrlich, S. D., Bork, P. & Wang, J., 2014, In: Nature Biotechnology. 32, 8, p. 834-845 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Blood pressure levels in male carriers of Arg82Cys in CD300LG

    Støy, J., Grarup, Niels, Hørlyck, A., Ibsen, L., Rungby, J., Poulsen, P. L., Brandslund, I., Christensen, C., Hansen, Torben, Pedersen, Oluf Borbye, Møller, N. & Kampmann, U., 2014, In: PLOS ONE. 9, 10, 6 p., e109646.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Dietary ascorbic acid and subsequent change in body weight and waist circumference: associations may depend on genetic predisposition to obesity - a prospective study of three independent cohorts

    Larsen, S. C., Ängquist, Lars, Ahluwalia, Tarun Veer Singh, Skaaby, T., Roswall, N., Tjønneland, A., Halkjær, J., Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Heitmann, B. L. & Sørensen, Thorkild I.A., 2014, In: Nutrition Journal. 13, p. 1-11 11 p., 43.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium: Diabetologia

    Koivula, R., Heggie, A., Barnett, A., Cederberg, H., Hansen, T. H., Koopman, A., Ridderstråle, M., Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M., Perry, M., Rauh, S., Siloaho, M., Teare, H. A., Thorand, B., Bell, J., Brunak, S., Frost, G. & 13 others, Jablonka, B., Mari, A., McDonald, T., Dekker, J., Hansen, Torben, Hattersley, A., Laakso, M., Pedersen, Oluf Borbye, Koivisto, V., Ruetten, H., Walker, M., Pearson, E. & Franks, P., 2014, In: Diabetologia. 57, 6, p. 1-11 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Effects of body size and change in body size from infancy through childhood on body mass index in adulthood

    Bjerregaard, L. G., Rasmussen, K. M., Michaelsen, Kim F., Skytthe, A., Mortensen, Erik Lykke, Baker, J. L. & Sørensen, Thorkild I.A., 2014, In: International Journal of Obesity. 38, 10, p. 1305-1311 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model

    Gao, R., Liu, Y., Gjesing, A. M. P., Hollensted, M., Wan, X., He, S., Pedersen, Oluf Borbye, Yi, X., Wang, J. & Hansen, Torben, 2014, In: B M C Genetics. 15, 9 p., 13.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Functional Screening Identifies miRNAs Influencing Apoptosis and Proliferation in Colorectal Cancer

    Christensen, L. L., Holm, A., Rantala, J., Kallioniemi, O., Rasmussen, M. H., Ostenfeld, M. S., Dagnaes-Hansen, F., Oster, B., Schepeler, T., Tobiasen, H., Thorsen, K., Sieber, O. M., Gibbs, P., Lamy, P., Hansen, T. F., Jakobsen, A., Riising, E. M., Helin, K., Lubinski, J., Hagemann-Madsen, R. & 3 others, Laurberg, S., Orntoft, T. F. & Andersen, C. L., 2014, In: PLOS ONE. 9, 6, p. e96767

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study

    Langenberg, C., Sharp, S. J., Franks, P. W., Scott, R. A., Deloukas, P., Forouhi, N. G., Froguel, P., Groop, L. C., Hansen, T., Palla, L., Pedersen, O., Schulze, M. B., Tormo, M-J., Wheeler, E., Agnoli, C., Arriola, L., Barricarte, A., Boeing, H., Clarke, G. M., Clavel-Chapelon, F. & 27 others, Duell, E. J., Fagherazzi, G., Kaaks, R., Kerrison, N. D., Key, T. J., Khaw, K. T., Kröger, J., Lajous, M., Morris, A. P., Navarro, C., Nilsson, P. M., Overvad, K., Palli, D., Panico, S., Quirós, J. R., Rolandsson, O., Sacerdote, C., Sánchez, M., Slimani, N., Spijkerman, A. M. W., Tumino, R., van der A, D. L., van der Schouw, Y. T., Barroso, I., McCarthy, M. I., Riboli, E. & Wareham, N. J., 2014, In: P L o S Medicine (Print). 11, 5, 14 p., e1001647.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

    Nielsen, H. B., Almeida, M., Juncker, A., Rasmussen, S., Li, J., Sunagawa, S., Plichta, D. R., Gautier, L., Pedersen, A. G., Le Chatelier, E., Pelletier, E., Bonde, I., Nielsen, T., Manichanh, C., Arumugam, M., Batto, J-M., dos Santos, M. B. Q., Blom, N., Borruel, N., Burgdorf, K. S. & 31 others, Boumezbeur, F., Casellas, F., Doré, J., Dworzynski, P., Guarner, F., Hansen, Torben, Hildebrand, F., Kaas, R. S., Kennedy, S., Kristiansen, Karsten, Kultima, J. R., Léonard, P., Levenez, F., Lund, O., Moumen, B., Le Paslier, D., Pons, N., Pedersen, Oluf Borbye, Prifti, E., Qin, J., Raes, J., Sørensen, Søren Johannes, Tap, J., Tims, S., Ussery, D., Yamada, T., Renault, P., Sicheritz-Pontén, T., Bork, P., Wang, J. & MetaHIT Consortium, M. C., 2014, In: Nature Biotechnology. 32, 8, p. 822–828 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Identification of Mislabeled Samples and Sample Mix-ups in Genotype Data using Barcode Genotypes

    Have, C. T., Appel, E. V. R., Grarup, Niels, Hansen, Torben & Bork-Jensen, J., 2014, In: International Journal of Bioscience, Biochemistry and Bioinformatics. 4, 5, p. 355-360 5 p., 370.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Interaction between genetic predisposition to adiposity and dietary protein in relation to subsequent change in body weight and waist circumference

    Ankarfeldt, Mikkel Zöllner, Larsen, S. C., Ängquist, Lars, Husemoen, L. L. N., Roswall, N., Overvad, K., Jakobsen, M. U., Halkjær, J., Tjønneland, A., Linneberg, Allan René, Toft, Ulla Marie Nørgaard, Hansen, Torben, Pedersen, Oluf Borbye, Heitmann, Berit, Astrup, A. & Sørensen, Thorkild I.A., 2014, In: P L o S One. 9, 10, 10 p., e110890.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Pleiotropic genes for metabolic syndrome and inflammation

    Kraja, A. T., Chasman, D. I., North, K. E., Reiner, A. P., Yanek, L. R., Oskari Kilpeläinen, T., Smith, J. A., Dehghan, A., Dupuis, J., Johnson, A. D., Feitosa, M. F., Tekola-Ayele, F., Chu, A. Y., Nolte, I. M., Dastani, Z., Morris, A., Pendergrass, S. A., Sun, Y. V., Ritchie, M. D., Vaez, A. & 31 others, Lin, H., Ligthart, S., Marullo, L., Rohde, R., Shao, Y., Ziegler, M. A., Im, H. K., Schnabel, R. B., Jørgensen, T., Jørgensen, M. E., Hansen, Torben, Pedersen, Oluf Borbye, Stolk, R. P., Snieder, H., Hofman, A., Uitterlinden, A. G., Franco, O. H., Ikram, M. A., Richards, J. B., Rotimi, C., Wilson, J. G., Lange, L., Ganesh, S. K., Nalls, M., Rasmussen-Torvik, L. J., Pankow, J. S., Coresh, J., Tang, W., Linda Kao, W. H., Boerwinkle, E. & Cross Consortia Pleiotropy (XC-Pleiotropy) Group, C. C. P. (. G., 2014, In: Molecular Genetics and Metabolism. 112, 4, p. 317-38 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Two randomized cross-over trials assessing the impact of dietary gluten or wholegrain on the gut microbiome and host metabolic health

    Ibrügger, S., Gøbel, R. J., drb459, drb459, Licht, T. R., Frøkiær, Hanne, Linneberg, Allan René, Hansen, Torben, Gupta, R., Pedersen, Oluf Borbye, Kristensen, M. B. & Lauritzen, Lotte, 2014, In: Journal of Clinical Trials. 4, 4, 9 p., 1000178.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population

    Li, S., Besenbacher, S., Li, Y., Kristiansen, Karsten, Grarup, Niels, Albrechtsen, Anders, Sparsø, T. H., Korneliussen, Thorfinn Sand, Hansen, Torben, Wang, J., Nielsen, Rasmus, Pedersen, Oluf Borbye, Bolund, L. & Schierup, M. H., 2014, In: European Journal of Human Genetics. 22, p. 1040-1045 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2013
  24. Published

    Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes

    Lohmueller, K. E., Sparsø, T. H., Li, Q., Galijatovic, E. A. A., Korneliussen, T. S., Albrechtsen, A., Banasik, K., Grarup, N., Hallgrimsdottir, I., Kiil, K., Oskari Kilpeläinen, T., Krarup, N. T., Pers, T. H., Sanchez, G., Hu, Y., DeGiorgio, M., Jørgensen, T., Sandbæk, A., Lauritzen, T., Brunak, S. & 6 others, Kristiansen, Karsten, Li, Y., Hansen, Torben, Wang, J., Nielsen, Rasmus & Pedersen, Oluf Borbye, 5 Dec 2013, In: American Journal of Human Genetics. 93, 6, p. 1072-1086 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

    Dimas, A. S., Lagou, V., Barker, A., Knowles, J. W., Mägi, R., Hivert, M-F., Benazzo, A., Rybin, D., Jackson, A. U., Stringham, H. M., Song, C., Fischer-Rosinsky, A., Boesgaard, T. W., Grarup, N., Abbasi, F. A., Assimes, T. L., Hao, K., Yang, X., Lecoeur, C., Barroso, I. & 31 others, Bonnycastle, L. L., Böttcher, Y., Bumpstead, S., Chines, P. S., Erdos, M. R., Graessler, J., Kovacs, P., Morken, M. A., Narisu, N., Payne, F., Stancakova, A., Swift, A. J., Tönjes, A., Bornstein, S. R., Cauchi, S., Froguel, P., Meyre, D., Schwarz, P. E. H., Häring, H., Smith, U., Boehnke, M., Bergman, R. N., Collins, F. S., Mohlke, K. L., Tuomilehto, J., Quertemous, T., Lind, L., Hansen, Torben, Pedersen, Oluf Borbye, Walker, M. & on behalf of the MAGIC investigators, O. B. O. T. M. I., 2 Dec 2013, In: Diabetes. 63, 6, p. 2158-2171 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Gut microbiota may have influence on glucose and lipid metabolism.

    Mikkelsen, K. H., Nielsen, M. F., Tvede, M., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 11 Nov 2013, In: Ugeskrift for Laeger. 175, 46, p. 2785-2788 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes

    Snogdal, L. S., Grarup, Niels, Banasik, Karina, Wod, M., Jørgensen, T., Witte, D. R., Lauritzen, T., Nielsen, A. A., Brandslund, I., Christensen, C., Pedersen, Oluf Borbye, Yderstræde, K. B., Beck-Nielsen, H., Henriksen, J. E., Hansen, Torben & Højlund, K., 25 Oct 2013, In: BMC Medical Genetics. 14, 1, p. 113

    Research output: Contribution to journal › Journal article › Research › peer-review

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