- 2021
- Published
Trans-ethnic gut microbiota signatures of type 2 diabetes in Denmark and India
Alvarez-Silva, C., Kashani, A., Hansen, T. H., Pinna, N. K., Anjana, R. M., Dutta, A., Saxena, S., Støy, J., Kampmann, U., Nielsen, T., Jørgensen, T., Gnanaprakash, V., Gnanavadivel, R., Sukumaran, A., Rani, C. S. S., Færch, K., Radha, V., Balasubramanyam, M., Nair, G. B., Das, B. & 6 others, , 2021, In: Genome Medicine. 13, 37.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial postbiotics as promising tools to mitigate cardiometabolic diseases
Anhê, F. F., Jensen, Benjamin Anderschou Holbech, Perazza, L. R., Tchernof, A., Schertzer, J. D. & Marette, A., 2021, In: Journal of Lipid and Atherosclerosis. 10, 2, p. 123-129 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Danish population-based case series of patients with liver cirrhosis and coronavirus disease 2019
Attauabi, M., Burisch, J., Bendtsen, Flemming & Kimer, N., 2021, In: Scandinavian Journal of Gastroenterology. 56, 4, p. 453-457Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein intake, metabolic status and the gut microbiota in different ethnicities: Results from two independent cohorts
Bel Lassen, P., Attaye, I., Adriouch, S., Nicolaou, M., Aron-Wisnewsky, J., Nielsen, T., Chakaroun, R., Le Chatelier, E., Forslund, S., Belda, E., Bork, P., Bäckhed, F., Stumvoll, M., Pedersen, O., Herrema, H., Groen, A. K., Pinto-Sietsma, S. J., Zwinderman, A. H., Nieuwdorp, M., Clement, K. & 1 others, , 2021, In: Nutrients. 13, 9, 3159.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study
Bizzotto, R., Jennison, C., Jones, A. G., Kurbasic, A., Tura, A., Kennedy, G., Bell, J. D., Thomas, E. L., Frost, G., Eriksen, R., Koivula, R. W., Brage, S., Kaye, J., Hattersley, A. T., Heggie, A., McEvoy, D., 't Hart, L. M., Beulens, J. W., Elders, P., Musholt, P. B. & 28 others, , 2021, In: Diabetes Care. 44, 2, p. 511-518 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Instrumental variable analysis using offspring BMI in childhood as an indicator of parental BMI in relation to mortality
Blond, K., Carslake, D., Gjærde, L. K., Vistisen, D., Sørensen, Thorkild I.A., Smith, G. D. & Baker, J. L., 2021, In: Scientific Reports. 11, 1, 10 p., 22408.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HBD-2 mutations are associated with childhood asthma and prophylactic hBD-2 application prevents asthma in mice
Borchers, N., Santos-Valente, E., Toncheva, A. A., Wehkamp, J., Franke, A., Gaertner, V. D., Nordkild, P., Genuneit, J., Jensen, Benjamin Anderschou Holbech & Kabesch, M., 2021, In: European Respiratory Journal. 58, Suppl. 65, 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human β-Defensin 2 Mutations Are Associated With Asthma and Atopy in Children and Its Application Prevents Atopic Asthma in a Mouse Model
Borchers, N. S., Santos-Valente, E., Toncheva, A. A., Wehkamp, J., Franke, A., Gaertner, V. D., Nordkild, P., Genuneit, J., Jensen, Benjamin Anderschou Holbech & Kabesch, M., 2021, In: Frontiers in Immunology. 12, 12 p., 636061.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-linear interaction between physical activity and polygenic risk score of body mass index in Danish and Russian populations
Borisevich, D., Schnurr, T. M., pjx571, pjx571, Rakitko, A., Ängquist, Lars, Ilinsky, V., Aadahl, Mette, Grarup, Niels, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Hansen, Torben, 2021, In: PLoS ONE. 16, 10, 16 p., e0258748.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human and preclinical studies of the host-gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health
Brial, F., Chilloux, J., Nielsen, T., Vieira-Silva, S., Falony, G., Andrikopoulos, P., Olanipekun, M., Hoyles, L., Djouadi, F., Neves, A. L., Rodriguez-Martinez, A., Mouawad, G. I., Pons, N., Forslund, S., Le-chatelier, E., Le Lay, A., Nicholson, J., Hansen, T., Hyotylainen, T., Clement, K. & 7 others, , 2021, In: Gut. 70, 11, p. 2105-2114 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The trans-ancestral genomic architecture of glycemic traits
Chen, J., Spracklen, C. N., Marenne, G., Varshney, A., Corbin, L. J., Luan, J., Willems, S. M., Wu, Y., Zhang, X., Horikoshi, M., Boutin, T. S., Magi, R., Waage, J., Li-Gao, R., Chan, K. H. K., Yao, J., Anasanti, M. D., Chu, A. Y., Claringbould, A., Heikkinen, J. & 31 others, , 2021, In: Nature Genetics. 53, 6, p. 840-860 41 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Abdominal and gluteofemoral fat depots show opposing associations with postprandial lipemia
Christiansen, Malene Revsbech, García Ureña, Mario, Borisevich, D., Grarup, Niels, Martínez, J. A., Oppert, J., Sørensen, Thorkild I.A., Hansen, Torben, Blaak, E. E. & Kilpeläinen, Tuomas O., 2021, In: American Journal of Clinical Nutrition. 114, 4, p. 1467–1475 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity
Deshmukh, H. A., Madsen, A. L., Viñuela, A., Have, C. T., Grarup, N., Tura, A., Mahajan, A., Heggie, A. J., Koivula, R. W., De Masi, F., Tsirigos, K. K., Linneberg, A., Drivsholm, T., Pedersen, O., Sørensen, T. I. A., Astrup, A., Gjesing, A. A. P., Pavo, I., Wood, A. R., Ruetten, H. & 14 others, , 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 1, p. 80-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-Like Peptide-1 Is Associated With Systemic Inflammation in Pediatric Patients Treated With Hematopoietic Stem Cell Transplantation
Sørum, Maria Ebbesen, Kissow, Hannelouise, Hartmann, Bolette, Kielsen, K., Sørensen, K., Stinson, Sara, Frithioff-Bojsoe, C., Fonvig, Cilius Esmann, Holm, Jens-Christian, Hansen, Torben, Holst, Jens Juul & Müller, K. G., 2021, In: Frontiers in Immunology. 12, 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study
Eloranta, A-M., Sallinen, T., Viitasalo, A., Lintu, N., Väistö, J., Jalkanen, H., Tompuri, T. T., Soininen, S., Haapala, E. A., Kiiskinen, S., Schnurr, T. M., Kilpeläinen, T. O., Mikkonen, S., Savonen, K., Atalay, M., Brage, S., Laaksonen, D. E., Lindi, V., Ågren, J., Schwab, U. & 2 others, , 2021, In: European Journal of Nutrition. 60, p. 425-434Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimation of SARS-CoV-2 Infection Fatality Rate by Real-time Antibody Screening of Blood Donors
Erikstrup, C., Hother, C. E., Pedersen, O. B. V., Mølbak, K., Skov, R. L., Holm, D. K., Saekmose, S. G., Nilsson, A. C., Brooks, P. T., Boldsen, J. K., Mikkelsen, C., Gybel-Brask, M., Sørensen, E., Dinh, K. M., Mikkelsen, S., Moller, B. K., Haunstrup, T., Harritshøj, L., Jensen, B. A., Hjalgrim, H. & 2 others, , 2021, In: Clinical Infectious Diseases. 72, 2, p. 249-253 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients
Farup, J., Just, J., de Paoli, F., Lin, L., Jensen, J. B., Billeskov, T., Roman, I. S., Cömert, C., Møller, A. B., Madaro, L., Groppa, E., Fred, R. G., Kampmann, U., Gormsen, L. C., Pedersen, S. B., Bross, P., Stevnsner, T., Eldrup, N., Pers, T. H., Rossi, F. M. V. & 2 others, , 2021, In: Cell Metabolism. 33, 11, p. 2201-2214.e11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Milk Oligosaccharides Modulate Fecal Microbiota and Are Safe for Use in Children With Overweight: A Randomized Controlled Trial
Fonvig, Cilius Esmann, Amundsen, I. D., Vigsnæs, L. K., Sørensen, N., Frithioff-Bojsoe, C., Christiansen, M., Hedley, P. L., Holm, L. A., McConnell, B. & Holm, Jens-Christian, 2021, In: Journal of Pediatric Gastroenterology and Nutrition. 73, 3, p. 408-414 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combinatorial, additive and dose-dependent drug–microbiome associations
Forslund, S. K., Chakaroun, R., Zimmermann-Kogadeeva, M., Markó, L., Aron-Wisnewsky, J., Nielsen, T., Moitinho-Silva, L., Schmidt, T. S. B., Falony, G., Vieira-Silva, S., Adriouch, S., Alves, R. J., Assmann, K., Bastard, J. P., Birkner, T., Caesar, R., Chilloux, J., Coelho, L. P., Fezeu, L., Galleron, N. & 23 others, , 2021, In: Nature. 600, p. 500-517 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies novel susceptibility loci for KIT D816V positive mastocytosis
Galatà, G., García-Montero, A. C., Kristensen, T., Dawoud, A. A. Z., Muñoz-González, J. I., Meggendorfer, M., Guglielmelli, P., Hoade, Y., Alvarez-Twose, I., Gieger, C., Strauch, K., Ferrucci, L., Tanaka, T., Bandinelli, S., Schnurr, T. M., Haferlach, T., Broesby-Olsen, S., Vestergaard, H., Møller, M. B., Bindslev-Jensen, C. & 7 others, , 2021, In: American Journal of Human Genetics. 108, 2, p. 284-294 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes
Goodrich, J. K., Singer-Berk, M., Son, R., Sveden, A., Wood, J., England, E., Cole, J. B., Weisburd, B., Watts, N., Caulkins, L., Dornbos, P., Koesterer, R., Zappala, Z., Zhang, H., Maloney, K. A., Dahl, A., Aguilar-Salinas, C. A., Atzmon, G., Barajas-Olmos, F., Barzilai, N. & 31 others, , 2021, In: Nature Communications. 12, 15 p., 3505.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The power of genetic diversity in genome-wide association studies of lipids
Graham, S. E., Clarke, S. L., Wu, K-H. H., Kanoni, S., Zajac, G. J. M., Ramdas, S., Surakka, I., Ntalla, I., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Hwang, M. Y., Han, S., Narita, A., Choudhury, A., Bentley, A. R., Ekoru, K., Verma, A., Trivedi, B. & 504 others, , 2021, In: Nature. 600, p. 675-679Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Explaining deep neural networks for knowledge discovery in electrocardiogram analysis
Hicks, S. A., Isaksen, Jonas L., Thambawita, V., Ghouse, Jonas, Ahlberg, Gustav, Linneberg, Allan René, Grarup, Niels, Strümke, I., Ellervik, Christina, Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., von Holstein-Rathlou, Niels-Henrik, Halvorsen, P., Maleckar, M. M., Riegler, M. A. & Kanters, Jørgen K., 2021, In: Scientific Reports. 11, 1, 11 p., 10949.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do genetic risk scores for childhood adiposity operate independent of BMI of their mothers?
Huang, L. O., Morgen, C. S., Ängquist, Lars, Nohr, E. A., Kilpeläinen, Tuomas O., Hansen, Torben, Sørensen, Thorkild I.A. & Schnurr, T. M., 2021, In: International Journal of Obesity. 45, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comprehensive lipidomics reveals phenotypic differences in hepatic lipid turnover in ALD and NAFLD during alcohol intoxication
Israelsen, M., Kim, M., Suvitaival, T., Madsen, B. S., Hansen, C. D., Torp, N., Trost, K., Thiele, M., Hansen, Torben, Legido-Quigley, C., Krag, A. & MicrobLiver Consortium, M. C., 2021, In: JHEP Reports. 3, 5, 11 p., 100325.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Estimation of allele frequency and association mapping using next-generation sequencing data
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