Hansen Group

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  1. 1993
  2. Published

    Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus

    Almind, K., Bjørbaek, C., drb459, drb459, Hansen, Torben, Echwald, S. M. & Pedersen, Oluf Borbye, 2 Oct 1993, In: Lancet. 342, 8875, p. 828-32 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Expression of insulin receptor spliced variants and their functional correlates in muscle from patients with non-insulin-dependent diabetes mellitus

    Hansen, Torben, Bjørbaek, C., drb459, drb459, Grønskov, K., Bak, J. F. & Pedersen, Oluf Borbye, Dec 1993, In: The Journal of clinical endocrinology and metabolism. 77, 6, p. 1500-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 1994
  5. Published

    Genetic variants in promoters and coding regions of the muscle glycogen synthase and the insulin-responsive GLUT4 genes in NIDDM

    Bjørbaek, C., Echwald, S. M., Hubricht, P., drb459, drb459, Hansen, Torben, Zierath, Juleen R & Pedersen, Oluf Borbye, Aug 1994, In: Diabetes. 43, 8, p. 976-83 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 1995
  7. Published

    Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity

    Echwald, S. M., Bjørbaek, C., Hansen, Torben, Clausen, J. O., drb459, drb459, Zierath, Juleen R, Printz, R. L., Granner, D. K. & Pedersen, Oluf Borbye, Mar 1995, In: Diabetes. 44, 3, p. 347-53 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2007
  9. Published

    The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

    Sparsø, T., Andersen, G., Nielsen, T., Burgdorf, K. S., Gjesing, A. M. P., Nielsen, A. L., Albrechtsen, Anders, Rasmussen, S. S., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetologia. 51, 1, p. 70-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects

    Gjesing, A. P., Andersen, G., Burgdorf, Kristoffer Sølvsten, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, Mar 2007, In: Diabetologia. 50, 3, p. 563-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2008
  12. Published

    The KCNMB1 Glu65Lys polymorphism associates with reduced systolic and diastolic blood pressure in the Inter99 study of 5729 Danes.

    Nielsen, T., Burgdorf, K. S., Grarup, Niels, Borch-Johnsen, K., Hansen, T., Jørgensen, T., Pedersen, Oluf Borbye & Andersen, G., 2008, In: Journal of Hypertension. 26, 11, p. 2142-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2009
  14. Published

    A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads

    Rose, C. S., Grarup, Niels, Krarup, N. T., Poulsen, P., Wegner, L., Nielsen, T., Banasik, Karina, Faerch, K., Andersen, G., Albrechtsen, Anders, Borch-Johnsen, K., Clausen, J. O., Jørgensen, T., Vaag, Allan, Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: Diabetologia. 52, 10, p. 2122-2129 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans

    Sparsø, T., Bonnefond, A., Andersson, E., Bouatia-Naji, N., Holmkvist, J., Wegner, L., Grarup, N., Gjesing, A. P., Banasik, K., Cavalcanti-Proença, C., Marchand, M., Vaxillaire, M., Charpentier, G., Jarvelin, M-R., Tichet, J., Balkau, B., Marre, M., Lévy-Marchal, C., Faerch, K., Borch-Johnsen, K. & 36 others, Jørgensen, T., Madsbad, Sten, Poulsen, P., Vaag, Allan, Dina, C., Hansen, T., Pedersen, Oluf Borbye, Froguel, P., Sparsø, T., Bonnefond, A., Andersson, E., Bouatia-Naji, N., Holmkvist, J., Wegner, L., Grarup, N., Gjesing, A. P., Banasik, K., Cavalcanti-Proença, C., Marchand, M., Vaxillaire, M., Charpentier, G., Jarvelin, M., Tichet, J., Balkau, B., Marre, M., Lévy-Marchal, C., Faerch, K., Borch-Johnsen, K., Jørgensen, T., Madsbad, Sten, Poulsen, P., Vaag, A., Dina, C., Hansen, T., Pedersen, O. & Froguel, P., 2009, In: Diabetes. 58, 6, p. 1450-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

    Perry, J. R. B., Weedon, M. N., Langenberg, C., Jackson, A. U., Lyssenko, V., Sparsø, T., Thorleifsson, G., Grallert, H., Ferrucci, L., Maggio, M., Paolisso, G., Walker, M., Palmer, C. N. A., Payne, F., Young, E., Herder, C., Narisu, N., Morken, M. A., Bonnycastle, L. L., Owen, K. R. & 38 others, Shields, B., Knight, B., Bennett, A., Groves, C. J., Ruokonen, A., Jarvelin, M. R., Pearson, E., Pascoe, L., Ferrannini, E., Bornstein, S. R., Stringham, H. M., Scott, L. J., Kuusisto, J., Nilsson, Carl Martin Peter, Neptin, M., Gjesing, A. P., Pisinger, C., Lauritzen, T., Sandbaek, A., Sampson, M., Zeggini, M. E., Lindgren, C. M., Steinthorsdottir, V., Thorsteinsdottir, U., Hansen, T., Schwarz, Peter, Illig, T., Laakso, M., Stefansson, K., Morris, A. D., Groop, L., Pedersen, Oluf Borbye, Boehnke, M., Barroso, I., Wareham, N. J., Hattersley, A. T., McCarthy, M. I. & Frayling, T. M., 2009, In: Human Molecular Genetics. 19, 3, p. 535-44 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2010
  18. Published

    Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

    Saxena, R., Hivert, M-F., Langenberg, C., Tanaka, T., Pankow, J. S., Vollenweider, P., Lyssenko, V., Bouatia-Naji, N., Dupuis, J., Jackson, A. U., Kao, W. H. L., Li, M., Glazer, N. L., Manning, A. K., Luan, J., Stringham, H. M., Prokopenko, I., Johnson, T., Grarup, N., Boesgaard, T. W. & 31 others, Lecoeur, C., Shrader, P., O'Connell, J., Ingelsson, E., Couper, D. J., Rice, K., Song, K., Andreasen, C. H., Dina, C., Köttgen, A., Le Bacquer, O., Pattou, F., Taneera, J., Steinthorsdottir, V., Rybin, D., Ardlie, K., Sampson, M., Qi, L., van Hoek, M., Weedon, M. N., Aulchenko, Y. S., Voight, B. F., Grallert, H., Balkau, B., Bergman, R. N., Borch-Johnsen, K., Jørgensen, T., Sparsø, T., Hansen, Torben, Pedersen, Oluf Borbye & GIANT Consortium, G. C., 1 Feb 2010, In: Nature Genetics. 42, 2, p. 142-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

    Dupuis, J., Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., Jackson, A. U., Wheeler, E., Glazer, N. L., Bouatia-Naji, N., Gloyn, A. L., Lindgren, C. M., Mägi, R., Morris, A. P., Randall, J., Johnson, T., Elliott, P., Rybin, D., Thorleifsson, G., Steinthorsdottir, V., Henneman, P. & 31 others, Grallert, H., Dehghan, A., Hottenga, J. J., Franklin, C. S., Navarro, P., Song, K., Goel, A., Perry, J. R. B., Egan, J. M., Lajunen, T., Grarup, Niels, Sparsø, T., Doney, A., Voight, B. F., Stringham, H. M., Li, M., Kanoni, S., Shrader, P., Cavalcanti-Proença, C., Kumari, M., Qi, L., Timpson, N. J., Gieger, C., Zabena, C., Rocheleau, G., Ingelsson, E., An, P., Jørgensen, T., Hansen, Torben, Pedersen, Oluf Borbye & DIAGRAM Consortium, D. C., 1 Feb 2010, In: Nature Genetics. 42, 2, p. 105-16 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes

    Burgdorf, K. S., Sandholt, C. H., Sparsø, T., Andersen, G., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Sørensen, Thorkild I.A., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 1 Jul 2010, In: European Journal of Endocrinology. 163, 1, p. 81-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., Hofmann, O. M. & 31 others, Dupuis, J., Qi, L., Segrè, A. V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Bengtsson Boström, K., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Grarup, Niels, Jørgensen, T., Sparsø, T., Hansen, Torben, Pedersen, Oluf Borbye & MAGIC investigators, M. I., 1 Jul 2010, In: Nature Genetics. 42, 7, p. 579-89 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    LMNA rs4641 and the muscle lamin A and C isoforms in twins--metabolic implications and transcriptional regulation

    Wegner, L., Anthonsen, S., Bork-Jensen, J., Dalgaard, L., Hansen, Torben, Pedersen, Oluf Borbye, Poulsen, P. & Vaag, Allan, Aug 2010, In: The Journal of clinical endocrinology and metabolism. 95, 8, p. 3884-92 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

    Gretarsdottir, S., Baas, A. F., Thorleifsson, G., Holm, H., den Heijer, M., de Vries, J-P. P. M., Kranendonk, S. E., Zeebregts, C. J. A. M., van Sterkenburg, S. M., Geelkerken, R. H., van Rij, A. M., Williams, M. J. A., Boll, A. P. M., Kostic, J. P., Jonasdottir, A., Jonasdottir, A., Walters, G. B., Masson, G., Sulem, P., Saemundsdottir, J. & 82 others, Mouy, M., Magnusson, K. P., Tromp, G., Elmore, J. R., Sakalihasan, N., Limet, R., Defraigne, J., Ferrell, R. E., Ronkainen, A., Ruigrok, Y. M., Wijmenga, C., Grobbee, D. E., Shah, S. H., Granger, C. B., Quyyumi, A. A., Vaccarino, V., Patel, R. S., Zafari, A. M., Levey, A. I., Austin, H., Girelli, D., Pignatti, P. F., Olivieri, O., Martinelli, N., Malerba, G., Trabetti, E., Becker, L. C., Becker, D. M., Reilly, M. P., Rader, D. J., Mueller, T., Dieplinger, B., Haltmayer, M., Urbonavicius, S., Lindblad, B., Gottsäter, A., Gaetani, E., Pola, R., Wells, P., Rodger, M., Forgie, M., Langlois, N., Corral, J., Vasquez, V., Fontcuberta, J., España, F., Grarup, Niels, Jørgensen, T., Witte, D. R., Hansen, Torben, Pedersen, Oluf Borbye, Aben, K. K., de Graaf, J., Holewijn, S., Folkersen, L., Franco-Cereceda, A., Eriksson, P., Collier, D. A., Stefansson, H., Steinthorsdottir, V., Rafnar, T., Valdimarsson, E. M., Magnadottir, H. B., Sveinbjornsdottir, S., Olafsson, I., Magnusson, M. K., Palmason, R., Haraldsdottir, V., Andersen, K., Onundarson, P. T., Thorgeirsson, G., Kiemeney, L. A., Powell, J. T., Carey, D. J., Kuivaniemi, H., Lindholt, J. S., Jones, G. T., Kong, A., Blankensteijn, J. D., Matthiasson, S. E., Thorsteinsdottir, U. & Stefansson, K., 1 Aug 2010, In: Nature Genetics. 42, 8, p. 692-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

    Boesgaard, T. W., Grarup, Niels, Jørgensen, T., Borch-Johnsen, K., Hansen, Torben, Pedersen, Oluf Borbye & Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC), M. O. G. A. I. T. C. (., 1 Aug 2010, In: Diabetologia. 53, 8, p. 1647-55 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight

    Andersson, E. A., Pilgaard, K., Pisinger, C., Harder, M. N., Grarup, Niels, Faerch, K., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Hansen, Torben & Pedersen, Oluf Borbye, 1 Sep 2010, In: Diabetologia. 53, 9, p. 1908-16 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Speliotes, E. K., Willer, C. J., Berndt, S. I., Monda, K. L., Thorleifsson, G., Jackson, A. U., Allen, H. L., Lindgren, C. M., Luan, J., Mägi, R., Randall, J. C., Vedantam, S., Winkler, T. W., Lu, Q., Workalemahu, T., Heid, I. M., Steinthorsdottir, V., Stringham, H. M., Weedon, M. N., Wheeler, E. & 31 others, Wood, A. R., Ferreira, T., Weyant, R. J., Segrè, A. V., Estrada, K., Liang, L., Nemesh, J., Park, J., Gustafsson, S., Kilpeläinen, Tuomas O., Yang, J., Bouatia-Naji, N., Esko, T., Feitosa, M. F., Kutalik, Z., Mangino, M., Raychaudhuri, S., Scherag, A., Smith, A. V., Welch, R., Zhao, J. H., Aben, K. K., Absher, D. M., Amin, N., Dixon, A. L., Gjesing, A. P., Jørgensen, T., Witte, D. R., Hansen, Torben, Pedersen, Oluf Borbye & MAGIC, M., 1 Nov 2010, In: Nature Genetics. 42, 11, p. 937-48 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

    Heid, I. M., Jackson, A. U., Randall, J. C., Winkler, T. W., Qi, L., Steinthorsdottir, V., Thorleifsson, G., Zillikens, M. C., Speliotes, E. K., Mägi, R., Workalemahu, T., White, C. C., Bouatia-Naji, N., Harris, T. B., Berndt, S. I., Ingelsson, E., Willer, C. J., Weedon, M. N., Luan, J., Vedantam, S. & 31 others, Esko, T., Kilpeläinen, Tuomas O., Kutalik, Z., Li, S., Monda, K. L., Dixon, A. L., Holmes, C. C., Kaplan, L. M., Liang, L., Min, J. L., Moffatt, M. F., Molony, C., Nicholson, G., Schadt, E. E., Zondervan, K. T., Feitosa, M. F., Ferreira, T., Allen, H. L., Weyant, R. J., Wheeler, E., Wood, A. R., Estrada, K., Goddard, M. E., Lettre, G., Mangino, M., Gjesing, A. P., Witte, D. R., Hansen, Torben, Jørgensen, T., Pedersen, Oluf Borbye & MAGIC, M., 1 Nov 2010, In: Nature Genetics. 42, 11, p. 949-60 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Glucokinase diabetes in 103 families from a country-based study in the Czech Republic: geographically restricted distribution of two prevalent GCK mutations

    Pruhova, S., Dusatkova, P., Sumnik, Z., Kolouskova, S., Pedersen, Oluf Borbye, Hansen, Torben, Cinek, O. & Lebl, J., 1 Dec 2010, In: Pediatric Diabetes Online. 11, 8, p. 529-35 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Low birthweight and premature birth are both associated with type 2 diabetes in a random sample of middle-aged Danes

    Pilgaard, K., Færch, K., Carstensen, B., Poulsen, P., Pisinger, C., Pedersen, Oluf Borbye, Witte, D. R., Hansen, Torben, Jørgensen, T. & Vaag, Allan, 1 Dec 2010, In: Diabetologia. 53, 12, p. 2526-30 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Physiologic characterization of type 2 diabetes-related loci

    Grarup, Niels, Sparsø, T. & Hansen, Torben, 1 Dec 2010, In: Current Diabetes Reports. 10, 6, p. 485-97 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2011
  32. Published

    Enterotypes of the human gut microbiome: [Plus]Corrigendum [Plus]Addendum

    Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., Fernandes, G. R., Tap, J., Bruls, T., Batto, J-M., dos Santos, M. B. Q., Borruel, N., Casellas, F., Fernandez, L., Gautier, L., Hansen, T., Hattori, M., Hayashi, T., Kleerebezem, M., Kurokawa, K. & 31 others, Leclerc, M., Levenez, F., Manichanh, C., Nielsen, H. B., Nielsen, T., Pons, N., Poulain, J., Qin, J., Sicheritz-Ponten, T., Tims, S., Torrents, D., Ugarte, E., Zoetendal, E. G., Wang, J., Guarner, F., Pedersen, Oluf Borbye, de Vos, W. M., Brunak, Søren, Doré, J., Antolín, M., Artiguenave, F., Blottiere, H. M., Almeida, M., Brechot, C., Cara, C., Chervaux, C., Cultrone, A., Delorme, C., Denariaz, G., Kristiansen, Karsten & MetaHIT Consortium, M. C., 2011, In: Nature. 473, 7346, p. 174-180 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Estimation of allele frequency and association mapping using next-generation sequencing data

    Kim, S. Y., Lohmueller, K. E., Albrechtsen, Anders, Li, Y., Korneliussen, Thorfinn Sand, Tian, G., Grarup, Niels, Jiang, T., Andersen, G., Witte, D., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2011, In: B M C Bioinformatics. 12, p. 231 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Genome wide association study identifies KCNMA1 contributing to human obesity

    Jiao, H., Arner, P., Hoffstedt, J., Brodin, D., Dubern, B., Czernichow, S., van't Hooft, F., Axelsson, T., Pedersen, Oluf Borbye, Hansen, Torben, Sørensen, Thorkild I.A., Hebebrand, J., Kere, J., Dahlman-Wright, K., Hamsten, A., Clement, K. & Dahlman, I., 2011, In: B M C Medical Genomics. 4, p. 51 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B

    Hribal, M. L., Presta, I., Procopio, T., Marini, M. A., Stancáková, A., Kuusisto, J., Andreozzi, F., Hammarstedt, A., Jansson, P., Grarup, Niels, Hansen, Torben, Walker, M., Stefan, N., Fritsche, A., Häring, H. U., Pedersen, Oluf Borbye, Smith, U., Laakso, M., Sesti, G. & EUGENE2 Consortium, E. C., 2011, In: Diabetologia. 54, 4, p. 795-802 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1

    Torekov, S. S., Ma, L., Grarup, N., Hartmann, B., Hainerová, I. A., Kielgast, U., Kissow, H., Rosenkilde, M., Lebl, J., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Madsen, O. D., Wang, J., Linneberg, A., Madsbad, S., Holst, J. J., Hansen, T., Pedersen, O. & 1 others, GIANT Consortium, G. C., 2011, In: Diabetologia. 54, 11, p. 2820-31 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Intrafamilial Variability of Early-Onset Diabetes due to an INS Mutation

    Fredheim, S., Svensson, Jannet, Pørksen, S., Hansen, L., Hansen, Torben, Pedersen, Oluf Borbye, Mortensen, H. B., Barbetti, F. & Nielsen, L. B., 2011, In: Case Reports in Genetics. 2011, p. 258978

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test

    Møller, J. B., Jusko, W. J., Gao, W., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Overgaard, R. V., Madsen, H. & Ingwersen, S. H., 2011, In: Journal of Pharmacokinetics and Pharmacodynamics. 38, 6, p. 713-25 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome

    Lohmueller, K. E., Albrechtsen, Anders, Li, Y., Kim, S. Y., Korneliussen, Thorfinn Sand, Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Feder, A. F., Grarup, Niels, Jørgensen, T., Jiang, T., Witte, D. R., Sandbæk, A., Hellmann, I., Lauritzen, T., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2011, In: P L o S Genetics. 7, 10, 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Studies of the Association of Arg72Pro of Tumor Suppressor Protein p53 with Type 2 Diabetes in a Combined Analysis of 55,521 Europeans

    Burgdorf, K. S., Grarup, Niels, Justesen, Johanne Marie, Harder, M. N., Witte, D. R., Jørgensen, T., Sandbæk, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben, DIAGRAM Consortium, D. C. & Pedersen, Oluf Borbye, 2011, In: P L o S One. 6, 1, p. e15813 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    A role for coding functional variants in HNF4A in type 2 diabetes susceptibility

    Jafar-Mohammadi, B., Groves, C. J., Gjesing, A. P., Herrera, B. M., Winckler, W., Stringham, H. M., Morris, A. P., Lauritzen, T., Doney, A. S. F., Morris, A. D., Weedon, M. N., Swift, A. J., Kuusisto, J., Laakso, M., Altshuler, D., Hattersley, A. T., Collins, F. S., Boehnke, M., Hansen, T., Pedersen, O. & 5 others, Palmer, C. N. A., Frayling, T. M., Gloyn, A. L., McCarthy, M. I. & DIAGRAM Consortium, D. C., Jan 2011, In: Diabetologia. 54, 1, p. 111-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

    Stacey, S. N., Sulem, P., Jonasdottir, A., Masson, G., Gudmundsson, J., Gudbjartsson, D. F., Magnusson, O. T., Gudjonsson, S. A., Sigurgeirsson, B., Thorisdottir, K., Ragnarsson, R., Benediktsdottir, K. R., Nexø, B. A., Tjønneland, A., Overvad, K., Rudnai, P., Gurzau, E., Koppova, K., Hemminki, K., Corredera, C. & 31 others, Fuentelsaz, V., Grasa, P., Navarrete, S., Fuertes, F., García-Prats, M. D., Sanambrosio, E., Panadero, A., De Juan, A., Garcia, A., Rivera, F., Planelles, D., Soriano, V., Requena, C., Aben, K. K., van Rossum, M. M., Cremers, R. G. H. M., van Oort, I. M., van Spronsen, D., Schalken, J. A., Peters, W. H. M., Helfand, B. T., Donovan, J. L., Hamdy, F. C., Badescu, D., Codreanu, O., Banasik, Karina, Jørgensen, T., Witte, D. R., Hansen, Torben, Pedersen, Oluf Borbye & Swedish Low-risk Colorectal Cancer Study Group, S. L. C. C. S. G., 1 Jan 2011, In: Nature Genetics. 43, 11, p. 1098-1103 6 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  43. Published

    A possible association between a dysfunctional skin barrier (filaggrin null-mutation status) and diabetes: a cross-sectional study

    Thyssen, Jacob Pontoppidan, Linneberg, Allan René, Carlsen, B. C., Johansen, Jeanne Duus, Engkilde, K., Hansen, Torben, Pociot, Flemming, Pedersen, Oluf Borbye, Meldgaard, M., Szecsi, P. B., Stender, Steen & Menné, T., 1 Jan 2011, In: BMJ Open. 1, 1, p. e000062 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease

    Banasik, Karina, Justesen, Johanne Marie, Hornbak, M., Krarup, N. T., Gjesing, A. P., Sandholt, C. H., Søndergaard Jensen, T., Grarup, Niels, Andersson, Åsa, Jørgensen, T., Witte, D. R., Sandbæk, A., Lauritzen, T., Thorens, B., Brunak, Søren, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: P L o S One. 6, 1, p. e16542

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test

    Gjesing, A. P., Kjems, L. L., Vestmar, M. A., Grarup, Niels, Linneberg, Allan René, Deacon, Carolyn F., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: Diabetologia. 54, 1, p. 103-10 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Corrigendum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

    Heid, I. M., Jackson, A. U., Randall, J. C., Winkler, T. W., Qi, L., Steinthorsdottir, V., Thorleifsson, G., Zillikens, M. C., Speliotes, E. K., Mägi, R., Workalemahu, T., White, C. C., Bouatia-Naji, N., Harris, T. B., Berndt, S. I., Ingelsson, E., Willer, C. J., Weedon, M. N., Luan, J., Vedantam, S. & 280 others, Esko, T., Kilpeläinen, T. O., Kutalik, Z., Li, S., Monda, K. L., Dixon, A. L., Holmes, C. C., Kaplan, L. M., Liang, L., Min, J. L., Moffatt, M. F., Molony, C., Nicholson, G., Schadt, E. E., Zondervan, K. T., Feitosa, M. F., Ferreira, T., Allen, H. L., Weyant, R. J., Wheeler, E., Wood, A. R., Estrada, K., Goddard, M. E., Lettre, G., Mangino, M., Nyholt, D. R., Purcell, S., Vernon Smith, A., Visscher, P. M., Yang, J., McCarroll, S. A., Nemesh, J., Voight, B. F., Absher, D., Amin, N., Aspelund, T., Coin, L., Glazer, N. L., Hayward, C., Heard-Costa, N. L., Hottenga, J., Johansson, A., Johnson, T., Kaakinen, M., Kapur, K., Ketkar, S., Knowles, J. W., Kraft, P., Kraja, A. T., Lamina, C., Leitzmann, M. F., McKnight, B., Morris, A. P., Ong, K. K., Perry, J. R. B., Peters, M. J., Polasek, O., Prokopenko, I., Rayner, N. W., Ripatti, S., Rivadeneira, F., Robertson, N. R., Sanna, S., Sovio, U., Surakka, I., Teumer, A., van Wingerden, S., Vitart, V., Zhao, J. H., Cavalcanti-Proença, C., Chines, P. S., Fisher, E., Kulzer, J. R., Lecoeur, C., Narisu, N., Sandholt, C., Scott, L. J., Silander, K., Stark, K., Tammesoo, M., Teslovich, T. M., Timpson, N. J., Watanabe, R. M., Welch, R., Chasman, D. I., Cooper, M. N., Jansson, J., Kettunen, J., Lawrence, R. W., Pellikka, N., Perola, M., Vandenput, L., Alavere, H., Almgren, P., Atwood, L. D., Bennett, A. J., Biffar, R., Bonnycastle, L. L., Bornstein, S. R., Buchanan, T. A., Campbell, H., Day, I. N. M., Dei, M., Dörr, M., Elliott, P., Erdos, M. R., Eriksson, J. G., Freimer, N. B., Fu, M., Gaget, S., Geus, E. J. C., Gjesing, A. P., Grallert, H., Gräßler, J., Groves, C. J., Guiducci, C., Hartikainen, A., Hassanali, N., Havulinna, A. S., Herzig, K., Hicks, A. A., Hui, J., Igl, W., Jousilahti, P., Jula, A., Kajantie, E., Kinnunen, L., Kolcic, I., Koskinen, S., Kovacs, P., Kroemer, H. K., Krzelj, V., Kuusisto, J., Kvaloy, K., Laitinen, J., Lantieri, O., Lathrop, G. M., Lokki, M., Luben, R. N., Ludwig, B., McArdle, W. L., McCarthy, A., Morken, M. A., Nelis, M., Neville, M. J., Paré, G., Parker, A. N., Peden, J. F., Pichler, I., Pietiläinen, K. H., Platou, C. G. P., Pouta, A., Ridderstråle, M., Samani, N. J., Saramies, J., Sinisalo, J., Smit, J. H., Strawbridge, R. J., Stringham, H. M., Swift, A. J., Teder-Laving, M., Thomson, B., Usala, G., van Meurs, J. B. J., van Ommen, G., Vatin, V., Volpato, C. B., Wallaschofski, H., Walters, G. B., Widen, E., Wild, S. H., Willemsen, G., Witte, D. R., Zgaga, L., Zitting, P., Beilby, J. P., James, A. L., Kähönen, M., Lehtimäki, T., Nieminen, M. S., Ohlsson, C., Palmer, L. J., Raitakari, O., Ridker, P. M., Stumvoll, M., Tönjes, A., Viikari, J., Balkau, B., Ben-Shlomo, Y., Bergman, R. N., Boeing, H., Smith, G. D., Ebrahim, S., Froguel, P., Hansen, Torben, Hengstenberg, C., Hveem, K., Isomaa, B., Jørgensen, T., Karpe, F., Khaw, K., Laakso, M., Lawlor, D. A., Marre, M., Meitinger, T., Metspalu, A., Midthjell, K., Pedersen, Oluf Borbye, Salomaa, V., Schwarz, P. E. H., Tuomi, T., Tuomilehto, J., Valle, T. T., Wareham, N. J., Arnold, A. M., Beckmann, J. S., Bergmann, S., Boerwinkle, E., Boomsma, D. I., Caulfield, M. J., Collins, F. S., Eiriksdottir, G., Gudnason, V., Gyllensten, U., Hamsten, A., Hattersley, A. T., Hofman, A., Hu, F. B., Illig, T., Iribarren, C., Jarvelin, M., Kao, W. H. L., Kaprio, J., Launer, L. J., Munroe, P. B., Oostra, B., Penninx, B. W., Pramstaller, P. P., Psaty, B. M., Quertermous, T., Rissanen, A., Rudan, I., Shuldiner, A. R., Soranzo, N., Spector, T. D., Syvanen, A., Uda, M., Uitterlinden, A., Völzke, H., Vollenweider, P., Wilson, J. F., Witteman, J. C., Wright, A. F., Abecasis, G. R., Boehnke, M., Borecki, I. B., Deloukas, P., Frayling, T. M., Groop, L. C., Haritunians, T., Hunter, D. J., Kaplan, R. C., North, K. E., O'Connell, J. R., Peltonen, L., Schlessinger, D., Strachan, D. P., Hirschhorn, J. N., Assimes, T. L., Wichmann, H., Thorsteinsdottir, U., van Duijn, C. M., Stefansson, K., Cupples, L. A., Loos, R. J. F., Barroso, I., McCarthy, M. I., Fox, C. S., Mohlke, K. L. & Lindgren, C. M., 1 Jan 2011, In: Nature Genetics. 43, 11, p. 1164 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  47. Published

    Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes

    Gjesing, A. P., Nielsen, A. A., Brandslund, I., Christensen, C., Sandbæk, A., Jørgensen, T., Witte, D., Bonnefond, A., Froguel, P., Hansen, Torben & Pedersen, Oluf Borbye, 1 Jan 2011, In: B M C Medical Genetics. 12, p. 99 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Studies of metabolic phenotypic correlates of 15 obesity associated gene variants

    Sandholt, C. H., Vestmar, M. A., Bille, D. S., Borglykke, A., Almind, K., Hansen, L., Sandbæk, A., Lauritzen, T., Witte, D., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: P L o S One. 6, 9, p. e23531 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The Effect of PCSK1 Variants on Waist, Waist-Hip Ratio and Glucose Metabolism Is Modified by Sex and Glucose Tolerance Status

    Gjesing, A. P., Vestmar, M. A., Jørgensen, T., Heni, M., Holst, Jens Juul, Witte, D. R., Hansen, Torben & Pedersen, Oluf Borbye, 1 Jan 2011, In: P L o S One. 6, 9, p. e23907 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    The FOXO3A rs2802292 G-Allele Associates with Improved Peripheral and Hepatic Insulin Sensitivity and Increased Skeletal Muscle-FOXO3A mRNA Expression in Twins

    Banasik, Karina, Ribel-Madsen, R., Gjesing, A. P., Wegner, L., Andersson, Åsa, Poulsen, P., Borglykke, A., Witte, D. R., Pedersen, Oluf Borbye, Hansen, Torben & Vaag, Allan, 1 Jan 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 1, p. E119-24

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load

    Hornbak, M., Banasik, Karina, Justesen, Johanne Marie, Krarup, N. T., Sandholt, C. H., Andersson, Åsa, Sandbaek, A., Lauritzen, T., Pisinger, C., Witte, D. R., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 6 Jan 2011, In: BMC Medical Genetics. 12, 1, p. 4 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes

    Pers, T. H., Hansen, N. T., Hansen, K. L., Koefoed, P., Dworzynski, P., Miller, M. L., Flint, T. J., Mellerup, E., Dam, H., Andreassen, O. A., Djurovic, S., Melle, I., Børglum, A. D., Werge, T., Purcell, S., Ferreira, M. A., Kouskoumvekaki, I., Workman, C., Hansen, T., Mors, O. & 1 others, Brunak, Søren, 11 Apr 2011, In: Genetic Epidemiology. 35, 5, p. 318-332 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Familial mild hyperglycemia associated with a novel ABCC8-V84I mutation within three generations

    Gonsorcikova, L., Vaxillaire, M., Pruhova, S., Dechaume, A., Dusatkova, P., Cinek, O., Pedersen, Oluf Borbye, Froguel, P., Hansen, Torben & Lebl, J., 1 May 2011, In: Pediatric Diabetes. 12, 3pt2, p. 266-9 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Implications of central obesity-related variants in LYPLAL1, NRXN3, MSRA, and TFAP2B on quantitative metabolic traits in adult Danes

    Bille, D. S., Banasik, Karina, Justesen, Johanne Marie, Sandholt, C. H., Sandbæk, A., Lauritzen, T., Jørgensen, T., Witte, D. R., Holm, Jens-Christian, Hansen, Torben & Pedersen, Oluf Borbye, 1 Jun 2011, In: P L o S One. 6, 6, p. e20640 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Comparison of Accuracy of Diabetes Risk Score and Components of the Metabolic Syndrome in Assessing Risk of Incident Type 2 Diabetes in Inter99 Cohort

    Shafizadeh, T. B., Moler, E. J., Kolberg, J. A., Nguyen, U. T., Hansen, Torben, Jørgensen, T., Pedersen, Oluf Borbye & Borch-Johnsen, K., 1 Jul 2011, In: P L o S One. 6, 7, p. e22863 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals

    Burgdorf, K. S., Gjesing, A. P., Grarup, Niels, Justesen, Johanne Marie, Sandholt, C. H., Witte, D. R., Jørgensen, T., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 28 Sep 2011, In: Diabetologia. 55, 1, p. 105-13 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    The Birth Weight Lowering C-Allele of rs900400 Near LEKR1 and CCNL1 Associates with Elevated Insulin Release following an Oral Glucose Challenge

    Andersson, E. A., Harder, M. N., Pilgaard, K., Pisinger, C., Stancáková, A., Kuusisto, J., Grarup, Niels, Færch, K., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Laakso, M., Pedersen, Oluf Borbye & Hansen, Torben, Nov 2011, In: P L o S One. 6, 11, p. e27096 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children

    Oskari Kilpeläinen, T., Qi, L., Brage, S., Sharp, S. J., Sonestedt, E., Demerath, E., Ahmad, T., Mora, S., Kaakinen, M., Sandholt, C. H., Holzapfel, C., Autenrieth, C. S., Hyppönen, E., Cauchi, S., He, M., Kutalik, Z., Kumari, M., Stancáková, A., Meidtner, K., Balkau, B. & 96 others, Tan, J. T., Mangino, M., Timpson, N. J., Song, Y., Zillikens, M. C., Jablonski, K. A., Garcia, M. E., Johansson, S., Bragg-Gresham, J. L., Wu, Y., van Vliet-Ostaptchouk, J. V., Onland-Moret, N. C., Zimmermann, E., Rivera, N. V., Tanaka, T., Stringham, H. M., Silbernagel, G., Kanoni, S., Feitosa, M. F., Snitker, S., Ruiz, J. R., Metter, J., Larrad, M. T. M., Atalay, M., Hakanen, M., Amin, N., Cavalcanti-Proença, C., Grøntved, A., Hallmans, G., Jansson, J., Kuusisto, J., Kähönen, M., Lutsey, P. L., Nolan, J. J., Palla, L., Pedersen, Oluf Borbye, Pérusse, L., Renström, F., Scott, R. A., Shungin, D., Sovio, U., Tammelin, T. H., Rönnemaa, T., Lakka, T. A., Uusitupa, M., Rios, M. S., Ferrucci, L., Bouchard, C., Meirhaeghe, A., Fu, M., Walker, M., Borecki, I. B., Dedoussis, G. V., Fritsche, A., Ohlsson, C., Boehnke, M., Bandinelli, S., van Duijn, C. M., Ebrahim, S., Lawlor, D. A., Gudnason, V., Harris, T. B., Sørensen, Thorkild I.A., Mohlke, K. L., Hofman, A., Uitterlinden, A. G., Tuomilehto, J., Lehtimäki, T., Raitakari, O., Isomaa, B., Njølstad, P. R., Florez, J. C., Liu, S., Ness, A., Spector, T. D., Tai, E. S., Froguel, P., Boeing, H., Laakso, M., Marmot, M., Bergmann, S., Power, C., Khaw, K., Chasman, D., Ridker, P., Hansen, Torben, Monda, K. L., Illig, T., Järvelin, M., Wareham, N. J., Hu, F. B., Groop, L. C., Orho-Melander, M., Ekelund, U., Franks, P. W. & Loos, R. J. F., 1 Nov 2011, In: P L o S Medicine (Online). 8, 11, p. e1001116

    Research output: Contribution to journal › Journal article › Research › peer-review

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