Hansen Group

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

Scott, R. A., Freitag, D. F., Li, L., Chu, A. Y., Surendran, P., Young, R., Grarup, N., Stancakova, A., Chen, Y., Varga, T. V., Yaghootkar, H., Luan, J., Zhao, J. H., Willems, S. M., Wessel, J., Wang, S., Maruthur, N., Michailidou, K., Pirie, A., van der Lee, S. J. & 119 others, Gillson, C., Al Olama, A. A., Amouyel, P., Arriola, L., Arveiler, D., Aviles-Olmos, I., Balkau, B., Barricarte, A., Barroso, I., Garcia, S. B., Bis, J. C., Blankenberg, S., Boehnke, M., Boeing, H., Boerwinkle, E., Borecki, I. B., Bork-Jensen, J., Bowden, S., Caldas, C., Caslake, M., Cupples, L. A., Cruchaga, C., Czajkowski, J., den Hoed, M., Dunn, J. A., Earl, H. M., Ehret, G. B., Ferrannini, E., Ferrieres, J., Foltynie, T., Ford, I., Forouhi, N. G., Gianfagna, F., Gonzalez, C., Grioni, S., Hiller, L., Jansson, J., Jørgensen, M. E., Jukema, J. W., Kaaks, R., Kee, F., Kerrison, N. D., Key, T. J., Kontto, J., Kote-Jarai, Z., Kraja, A. T., Kuulasmaa, K., Kuusisto, J., Linneberg, Allan René, Liu, C., Marenne, G., Mohlke, K. L., Morris, A. P., Muir, K., Mueller-Nurasyid, M., Munroe, P. B., Navarro, C., Nielsen, S. F., Nilsson, P. M., Nordestgaard, B. G., Packard, C. J., Palli, D., Panico, S., Peloso, G. M., Perola, M., Peters, A., Poole, C. J., Quiros, J. R., Rolandsson, O., Sacerdote, C., Salomaa, V., Sanchez, M., Sattar, N., Sharp, S. J., Sims, R., Slimani, N., Smith, J. A., Thompson, D. J., Trompet, S., Tumino, R., van der A, D. L., van der Schouw, Y. T., Virtamo, J., Walker, M., Walter, K., Abraham, J. E., Amundadottir, L. T., Aponte, J. L., Butterworth, A., Dupuis, J., Easton, D. F., Eeles, R. A., Erdmann, J., Franks, P. W., Frayling, T. M., Hansen, Torben, Howson, J. M. M., Jørgensen, T., Kooner, J., Laakso, M., Langenberg, C., McCarthy, M. I., Pankow, J. S., Pedersen, Oluf Borbye, Riboli, E., Rotter, J. I., Saleheen, D., Samani, N. J., Schunkert, H., Vollenweider, P., O'Rahilly, S., Deloukas, P., Danesh, J., Goodarzi, M. O., Kathiresan, S., Meigs, J. B., Ehm, M. G., Wareham, N. J. & Waterworth, D. M., 1 Jun 2016, In: Science Translational Medicine. 8, 341, 13 p., 341ra76.

Research output: Contribution to journal › Journal article › Research › peer-review

Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A. B., Norddahl, G. L., Helgadottir, A., Magnusdottir, A., Jonasdottir, A., Gretarsdottir, S., Jonsdottir, I., Steinthorsdottir, V., Rafnar, T., Swinkels, D. W., Galesloot, T. E., Grarup, N., Jørgensen, T., Vestergaard, H., Hansen, T., Lauritzen, T. & 34 others, Linneberg, Allan René, Friedrich, N., Krarup, N. T., Fenger, M., Abildgaard, U., Hansen, Peter Riis, Galløe, A. M., Braund, P. S., Nelson, C. P., Hall, A. S., Williams, M. J. A., van Rij, A. M., Jones, G. T., Patel, R. S., Levey, A. I., Hayek, S., Shah, S. H., Reilly, M., Eyjolfsson, G. I., Sigurdardottir, O., Olafsson, I., Kiemeney, L. A., Quyyumi, A. A., Rader, D. J., Kraus, W. E., Samani, N. J., Pedersen, Oluf Borbye, Thorgeirsson, G., Masson, G., Holm, H., Gudbjartsson, D., Sulem, P., Thorsteinsdottir, U. & Stefansson, K., 2 Jun 2016, In: New England Journal of Medicine. 374, 22, p. 2131-2141 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

Chami, N., Chen, M-H., Slater, A. J., Eicher, J. D., Evangelou, E., Tajuddin, S. M., Love-Gregory, L., Kacprowski, T., Schick, U. M., Nomura, A., Giri, A., Lessard, S., Brody, J. A., Schurmann, C., Pankratz, N., Yanek, L. R., Manichaikul, A., Pazoki, R., Mihailov, E., Hill, W. D. & 93 others, Raffield, L. M., Burt, A., Bartz, T. M., Becker, D. M., Becker, L. C., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., O'Donoghue, M. L., Crosslin, D. R., de Denus, S., Dubé, M., Elliott, P., Engström, G., Evans, M. K., Floyd, J. S., Fornage, M., Gao, H., Greinacher, A., Gudnason, V., Hansen, Torben, Harris, T. B., Hayward, C., Hernesniemi, J., Highland, H. M., Hirschhorn, J. N., Hofman, A., Irvin, M. R., Kähönen, M., Lange, E., Launer, L. J., Lehtimäki, T., Li, J., Liewald, D. C. M., Linneberg, Allan René, Liu, Y., Lu, Y., Lyytikäinen, L., Mägi, R., Mathias, R. A., Melander, O., Metspalu, A., Mononen, N., Nalls, M. A., Nickerson, D. A., Nikus, K., O'Donnell, C. J., Orho-Melander, M., Pedersen, Oluf Borbye, Petersmann, A., Polfus, L., Psaty, B. M., Raitakari, O. T., Raitoharju, E., Richard, M., Rice, K. M., Rivadeneira, F., Rotter, J. I., Schmidt, F., Smith, A. V., Starr, J. M., Taylor, K. D., Teumer, A., Thuesen, B. H., Torstenson, E. S., Tracy, R. P., Tzoulaki, I., Zakai, N. A., Vacchi-Suzzi, C., van Duijn, C. M., van Rooij, F. J. A., Cushman, M., Deary, I. J., Velez Edwards, D. R., Vergnaud, A., Wallentin, L., Waterworth, D. M., White, H. D., Wilson, J. G., Zonderman, A. B., Kathiresan, S., Grarup, Niels, Esko, T., Loos, R. J. F., Lange, L. A., Faraday, N., Abumrad, N. A., Edwards, T. L., Ganesh, S. K., Auer, P. L., Johnson, A. D., Reiner, A. P. & Lettre, G., 7 Jul 2016, In: American Journal of Human Genetics. 99, 1, p. 8-21 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Role of the Gut Microbiota in Childhood Obesity

Pihl, A. F., Fonvig, C. E., Stjernholm, T., Hansen, Torben, Pedersen, Oluf Borbye & Holm, Jens-Christian, 25 Jul 2016, In: Childhood Obesity. 12, 4, p. 292-299 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic risk scores link body fat distribution with specific cardiometabolic profiles

Svendstrup, M., Sandholt, C. H., Andersson Galijatovic, E. A., Linneberg, Allan René, Jørgensen, T., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Grarup, Niels, Hansen, Torben & drb459, drb459, Aug 2016, In: Obesity. 24, 8, p. 1778-1785 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits

CHARGE Consortium Hematology Working Group, C. C. H. W. G., Aug 2016, In: Nature Genetics. 48, 8, p. 867-876 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The genetic architecture of type 2 diabetes

Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Fernandez Tajes, J., Highland, H. M. & 281 others, Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, Niels, Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B., Kim, Y., Kim, Y. J., Kwon, M., Lee, J., Lee, S., Lin, K., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stancáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., van der Schouw, Y. T., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, Johanne Marie, Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, Allan René, Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., Hrabé de Angelis, M., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, Torben, Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, Oluf Borbye, Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Burtt, N. P., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Florez, J. C., Scott, L. J., Morris, A. P., Kang, H. M., Boehnke, M., Altshuler, D. & McCarthy, M. I., 4 Aug 2016, In: Nature. 536, 7614, p. 41-47 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Insulin Resistance is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation

Faerch, K., Vistisen, D., Pacini, G., Torekov, Signe Sørensen, Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Jørgensen, M. E., Ahrén, B. & Holst, Jens Juul, 8 Aug 2016, In: Diabetes. 65, 11, p. 3473-3481 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Transcriptional interactions suggest niche segregation among microorganisms in the human gut

Plichta, D. R., Juncker, A. S., Bertalan, M., Rettedal, E., Gautier, L., Varela, E., Manichanh, C., Fouqueray, C., Levenez, F., Nielsen, T., Doré, J., Machado, A. M. D., de Evgrafov, M. C. R., Hansen, T., Jørgensen, T., Bork, P., Guarner, F., Pedersen, O., Metagenomics of the Human Intestinal Tract (MetaHIT) Consortium, Sommer, M. O. A. & 4 others, Ehrlich, S. D., Sicheritz-Pontén, T., Brunak, Søren & Nielsen, H. B., 26 Aug 2016, In: Nature Microbiology. 1, p. 1-6 6 p., 16152.

Research output: Contribution to journal › Letter › Research › peer-review

Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population

Vestmar, M. A., Galijatovic, E. A. A., Christensen, C. R., Pedersen, M. H., Glümer, C., Linneberg, Allan René, Witte, D. R., Jørgensen, M. E., Christensen, C., Brandslund, I., Lauritzen, T., Pedersen, Oluf Borbye, Holst, Birgitte, Grarup, Niels, Schwartz, Thue W. & Hansen, Torben, Sep 2016, In: Journal of Medical Genetics. 53, 9, p. 616-23 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P., Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A., Harakalova, M. & 32 others, Mihailov, E., Liu, C., Kraja, A. T., Nielsen, S. F., Rasheed, A., Samuel, M., Zhao, W., Bonnycastle, L. L., Jackson, A. U., Narisu, N., Swift, A. J., Southam, L., Marten, J., Huyghe, J. R., Stančáková, A., Fava, C., Ohlsson, T., Matchan, A., Stirrups, K. E., Bork-Jensen, J., Gjesing, A. P., Kontto, J., Perola, M., Shaw-Hawkins, S., Havulinna, A. S., Husemoen, L. L., Linneberg, Allan René, Hansen, Torben, Pedersen, Oluf Borbye, Nordestgaard, Børge, CHARGE-Heart Failure Consortium, C. F. C. & V Varga, Tibor, 12 Sep 2016, In: Nature Genetics. 48, 10, p. 1151-1161 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide associations for birth weight and correlations with adult disease

Horikoshi, M., Beaumont, R. N., Day, F. R., Warrington, N. M., Kooijman, M. N., Fernandez-Tajes, J., Feenstra, B., van Zuydam, N. R., Gaulton, K. J., Grarup, N., Bradfield, J. P., Strachan, D. P., Li-Gao, R., Ahluwalia, T. V. S., Kreiner, E., Rueedi, R., Lyytikäinen, L-P., Cousminer, D. L., Wu, Y., Thiering, E. & 31 others, Wang, C. A., Have, C. T., Hottenga, J., Vilor-Tejedor, N., Joshi, P. K., Boh, E. T. H., Ntalla, I., Pitkänen, N., Mahajan, A., van Leeuwen, E. M., Joro, R., Lagou, V., Nodzenski, M., Diver, L. A., Zondervan, K. T., Bustamante, M., Marques-Vidal, P., Mercader, J. M., Appel, E. V. R., Waage, J., Sørensen, Thorkild I.A., Melbye, M., Kadarmideen, H. N., Holm, Jens-Christian, Hansen, Torben, Bønnelykke, Klaus, Bisgaard, H., Pisinger, C., Pedersen, Oluf Borbye, Vaag, Allan & CHARGE Consortium Hematology Working Group, C. C. H. W. G., 28 Sep 2016, In: Nature. 538, p. 248-252 5 p.

Research output: Contribution to journal › Letter › Research › peer-review

Genome-wide association study of the modified Stumvoll Insulin Sensitivity Index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci

Walford, G. A., Gustafsson, S., Rybin, D., Stančáková, A., Chen, H., Liu, C-T., Hong, J., Jensen, R. A., Rice, K., Morris, A. P., Mägi, R., Tönjes, A., Prokopenko, I., Kleber, M. E., Delgado, G., Silbernagel, G., Jackson, A. U., Appel, E. V., Grarup, N., Lewis, J. P. & 59 others, Montasser, M. E., Landenvall, C., Staiger, H., Luan, J., Frayling, T. M., Weedon, M. N., Xie, W., Morcillo, S., Martínez-Larrad, M. T., Biggs, M. L., Ida Chen, Y., Corbaton-Anchuelo, A., Faerch, K., Zumaquero, J. M., Goodarzi, M. O., Kizer, J., Koistinen, H. A., Leong, A., Lind, L., Lindgren, C., Machicao, F., Manning, A. K., Martín-Núñez, G. M., Rojo-Martínez, G., Rotter, J. I., Siscovick, D. S., Zmuda, J. M., Zhang, Z., Serrano-Rios, M., Smith, U., Soriguer, F., Hansen, Torben, Jørgensen, T., Linnenberg, A., Pedersen, Oluf Borbye, Walker, M., Langenberg, C., Scott, R. A., Wareham, N. J., Fritsche, A., Häring, H., Stefan, N., Groop, L., O'Connell, J. R., Boehnke, M., Bergman, R. N., Collins, F. S., Mohlke, K. L., Tuomilehto, J., März, W., Kovacs, P., Stumvoll, M., Psaty, B. M., Kuusisto, J., Laakso, M., Meigs, J. B., Dupuis, J., Ingelsson, E. & Florez, J. C., Oct 2016, In: Diabetes. 65, 10, p. 3200-3211 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Vejle diabetes Biobank: A resource for studies of the etiologies of diabetes and its comorbidities

Petersen, E. R. B., Nielsen, A. A., Christensen, H., Hansen, Torben, Pedersen, Oluf Borbye, Christensen, C. K. & Brandslund, I., 21 Oct 2016, In: Clinical Epidemiology. 8, p. 393-413 21 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology

Schnurr, T. M., Gjesing, A. M. P., Sandholt, C. H., Jonsson, Anna Elisabet, Mahendran, Y., Have, C. T., Ekstrøm, Claus Thorn, Bjerregaard, A., Brage, S., Witte, D., Jørgensen, M. E., Aadahl, Mette, Thuesen, B. H., Linneberg, Allan René, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye, Grarup, Niels, Kilpeläinen, Tuomas O. & Hansen, Torben, 15 Nov 2016, In: P L o S One. 11, 11, 14 p., e0166738.

Research output: Contribution to journal › Journal article › Research › peer-review

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

Ried, J. S., Jeff M, J., Chu, A. Y., Bragg-Gresham, J. L., van Dongen, J., Huffman, J. E., Ahluwalia, T. V. S., Cadby, G., Eklund, N., Eriksson, J., Esko, T., Feitosa, M. F., Goel, A., Gorski, M., Hayward, C., Heard-Costa, N. L., Jackson, A. U., Jokinen, E., Kanoni, S., Kristiansson, K. & 256 others, Kutalik, Z., Lahti, J., Luan, J., Mägi, R., Mahajan, A., Mangino, M., Medina-Gomez, C., Monda, K. L., Nolte, I. M., Pérusse, L., Prokopenko, I., Qi, L., Rose, L. M., Salvi, E., Smith, M. T., Snieder, H., Stančáková, A., Ju Sung, Y., Tachmazidou, I., Teumer, A., Thorleifsson, G., van der Harst, P., Walker, R. W., Wang, S. R., Wild, S. H., Willems, S. M., Wong, A., Zhang, W., Albrecht, E., Couto Alves, A., Bakker, S. J. L., Barlassina, C., Bartz, T. M., Beilby, J., Bellis, C., Bergman, R. N., Bergmann, S., Blangero, J., Blüher, M., Boerwinkle, E., Bonnycastle, L. L., Bornstein, S. R., Bruinenberg, M., Campbell, H., Chen, Y. I., Chiang, C. W. K., Chines, P. S., Collins, F. S., Cucca, F., Cupples, L. A., D'Avila, F., de Geus, E. J. C., Dedoussis, G., Dimitriou, M., Döring, A., Eriksson, J. G., Farmaki, A., Farrall, M., Ferreira, T., Fischer, K., Forouhi, N. G., Friedrich, N., Gjesing, A. M. P., Glorioso, N., Graff, M., Grallert, H., Grarup, Niels, Gräßler, J., Grewal, J., Hamsten, A., Harder, M. N., Hartman, C. A., Hassinen, M., Hastie, N., Hattersley, A. T., Havulinna, A. S., Heliövaara, M., Hillege, H., Hofman, A., Holmen, O., Homuth, G., Hottenga, J., Hui, J., Husemoen, L. L., Hysi, P. G., Isaacs, A., Ittermann, T., Jalilzadeh, S., James, A. L., Jørgensen, T., Jousilahti, P., Jula, A., Justesen, Johanne Marie, Justice, A. E., Kähönen, M., Karaleftheri, M., Tee Khaw, K., Keinanen-Kiukaanniemi, S. M., Kinnunen, L., Knekt, P. B., Koistinen, H. A., Kolcic, I., Kooner, I. K., Koskinen, S., Kovacs, P., Kyriakou, T., Laitinen, T., Langenberg, C., Lewin, A. M., Lichtner, P., Lindgren, C. M., Lindström, J., Linneberg, Allan René, Lorbeer, R., Lorentzon, M., Luben, R., Lyssenko, V., Männistö, S., Manunta, P., Leach, I. M., McArdle, W. L., Mcknight, B., Mohlke, K. L., Mihailov, E., Milani, L., Mills, R., Montasser, M. E., Morris, A. P., Müller, G., Musk, A. W., Narisu, N., Ong, K. K., Oostra, B. A., Osmond, C., Palotie, A., Pankow, J. S., Paternoster, L., Penninx, B. W., Pichler, I., Pilia, M. G., Polašek, O., Pramstaller, P. P., Raitakari, O. T., Rankinen, T., Rao, D. C., Rayner, N. W., Ribel-Madsen, R., Rice, T. K., Richards, M., Ridker, P. M., Rivadeneira, F., Ryan, K. A., Sanna, S., Sarzynski, M. A., Scholtens, S., Scott, R. A., Sebert, S., Southam, L., Sparsø, T. H., Steinthorsdottir, V., Stirrups, K., Stolk, R. P., Strauch, K., Stringham, H. M., Swertz, M. A., Swift, A. J., Tönjes, A., Tsafantakis, E., van der Most, P. J., Van Vliet-Ostaptchouk, J. V., Vandenput, L., Vartiainen, E., Venturini, C., Verweij, N., Viikari, J. S., Vitart, V., Vohl, M., Vonk, J. M., Waeber, G., Widén, E., Willemsen, G., Wilsgaard, T., Winkler, T. W., Wright, A. F., Yerges-Armstrong, L. M., Hua Zhao, J., Carola Zillikens, M., Boomsma, D. I., Bouchard, C., Chambers, J. C., Chasman, D. I., Cusi, D., Gansevoort, R. T., Gieger, C., Hansen, Torben, Hicks, A. A., Hu, F., Hveem, K., Jarvelin, M., Kajantie, E., Kooner, J. S., Kuh, D., Kuusisto, J., Laakso, M., Lakka, T. A., Lehtimäki, T., Metspalu, A., Njølstad, I., Ohlsson, C., Oldehinkel, A. J., Palmer, L. J., Pedersen, Oluf Borbye, Perola, M., Peters, A., Psaty, B. M., Puolijoki, H., Rauramaa, R., Rudan, I., Salomaa, V., Schwarz, Peter, Shudiner, A. R., Smit, J. H., Sørensen, Thorkild I.A., Spector, T. D., Stefansson, K., Stumvoll, M., Tremblay, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., Völker, U., Vollenweider, P., Wareham, N. J., Watkins, H., Wilson, J. F., Zeggini, E., Abecasis, G. R., Boehnke, M., Borecki, I. B., Deloukas, P., van Duijn, C. M., Fox, C., Groop, L. C., Heid, I. M., Hunter, D. J., Kaplan, R. C., McCarthy, M. I., North, K. E., O'Connell, J. R., Schlessinger, D., Thorsteinsdottir, U., Strachan, D. P., Frayling, T., Hirschhorn, J. N., Müller-Nurasyid, M. & Loos, R. J. F., 23 Nov 2016, In: Nature Communications. 7, 11 p., 13357.

Research output: Contribution to journal › Journal article › Research › peer-review

(1)H-MRS measured ectopic fat in liver and muscle is associated with the metabolic syndrome in Danish girls but not in boys with overweight and obesity

Nissen, A., Fonvig, C. E., Chabanova, E., Bøjsøe, C., Trier, C., Pedersen, Oluf Borbye, Hansen, Torben, Thomsen, Henrik S. & Holm, Jens-Christian, Dec 2016, In: Obesity Science & Practice. 2, 4, p. 376-384 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Increasing insulin resistance accentuates the effect of triglyceride-associated loci on serum triglycerides during 5 years

Justesen, Johanne Marie, Andersson, E. A., Allin, K. H., Sandholt, C. H., Jørgensen, T., Linneberg, Allan René, Jørgensen, M. E., Hansen, Torben, Pedersen, Oluf Borbye & Grarup, Niels, Dec 2016, In: Journal of Lipid Research. 57, 12, p. 2193-2199 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Weight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels

pjx571, pjx571, Iepsen, E. P. W., Galijatovic, E. A. A., Mahendran, Y., Lundgren, J. R., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, Dec 2016, In: Metabolomics. 12, 12, p. 1-9 9 p., 181.

Research output: Contribution to journal › Journal article › Research › peer-review

A Genome-Wide Association Study of IVGTT-Based Measures of First Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

Wood, A. R., Jonsson, A., Jackson, A. U., Wang, T-N., van Leewen, N., Palmer, N. D., Kobes, S., Deelen, J., Boquete-Vilarino, L., Paananen, J., Stančáková, A., Boomsma, D. I., de Geus, E. J., Eekhoff, E. M., Fritsche, A., Kramer, M., Nijpels, G., Simonis-Bik, A. M. C., van Haeften, T. W., Mahajan, A. & 31 others, Boehnke, M., Bergman, R. N., Tuomilehto, J., Collins, F. S., Mohlke, K. L., Banasik, Karina, Groves, C. J., McCarthy, M. I., Pearson, E. R., Natali, A., Mari, A., Buchanan, T. A., Taylor, K. D., Xiang, A. H., Gjesing, A. P., Grarup, Niels, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye, Chen, Y., Laakso, M., Norris, J. M., Smith, U., Wagenknecht, L. E., Baier, L., Bowden, D. W., Hansen, Torben, Walker, M., Watanabe, R. M., 't Hart, L. M., Hanson, R. L. & Frayling, T. M., 2017, In: Diabetes. 66, 8, p. 2296-2309

Research output: Contribution to journal › Journal article › Research › peer-review

A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents

Nielsen, T. R. H., Appel, E. V. R., Svendstrup, M., Ohrt, J. D., Dahl, M., Fonvig, C. E., Hollensted, M., Have, C. T., Kadarmideen, H. N., Pedersen, Oluf Borbye, Hansen, Torben, Holm, Jens-Christian & Grarup, Niels, 2017, In: PloS one. 12, 3, 16 p., e0174204.

Research output: Contribution to journal › Journal article › Research › peer-review

A study of associations between early DHA status and fatty acid desaturase (FADS) SNP and developmental outcomes in children of obese mothers

Andersen, K. R., Harsløf, L. B. S., Schnurr, T. M., Hansen, Torben, Hellgren, L. I., Michaelsen, Kim F. & Lauritzen, Lotte, 2017, In: The British Journal of Nutrition. 117, 2, p. 278-286 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Scott, R. A., Scott, L. J., Mägi, R., Marullo, L., Gaulton, K. J., Kaakinen, M., Pervjakova, N., Pers, T. H., Johnson, A. D., Eicher, J. D., Jackson, A. U., Ferreira, T., Lee, Y., Ma, C., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Van Zuydam, N. R., Mahajan, A., Chen, H. & 155 others, Almgren, P., Voight, B. F., Grallert, H., Müller-Nurasyid, M., Ried, J. S., Rayner, W. N., Robertson, N., Karssen, L. C., van Leeuwen, E. M., Willems, S. M., Fuchsberger, C., Kwan, P., Teslovich, T. M., Chanda, P., Li, M., Lu, Y., Dina, C., Thuillier, D., Yengo, L., Jiang, L., Sparso, T., Kestler, H. A., Chheda, H., Eisele, L., Gustafsson, S., Frånberg, M., Strawbridge, R. J., Benediktsson, R., Hreidarsson, A. B., Kong, A., Sigurðsson, G., Kerrison, N. D., Luan, J., Liang, L., Meitinger, T., Roden, M., Thorand, B., Esko, T., Mihailov, E., Fox, C., Liu, C., Rybin, D., Isomaa, B., Lyssenko, V., Tuomi, T., Couper, D. J., Pankow, J. S., Grarup, Niels, Have, C. T., Jørgensen, M. E., Jørgensen, T., Linneberg, Allan René, Cornelis, M. C., van Dam, R. M., Hunter, D. J., Kraft, P., Sun, Q., Edkins, S., Owen, K. R., Perry, J. R., Wood, A. R., Zeggini, E., Tajes-Fernandes, J., Abecasis, G. R., Bonnycastle, L. L., Chines, P. S., Stringham, H. M., Koistinen, H. A., Kinnunen, L., Sennblad, B., Mühleisen, T. W., Nöthen, M. M., Pechlivanis, S., Baldassarre, D., Gertow, K., Humphries, S. E., Tremoli, E., Klopp, N., Meyer, J., Steinbach, G., Wennauer, R., Eriksson, J. G., Mӓnnistö, S., Peltonen, L., Tikkanen, E., Charpentier, G., Eury, E., Lobbens, S., Gigante, B., Leander, K., McLeod, O., Bottinger, E. P., Gottesman, O., Ruderfer, D., Blüher, M., Kovacs, P., Tonjes, A., Maruthur, N. M., Scapoli, C., Erbel, R., Jöckel, K., Moebus, S., de Faire, U., Hamsten, A., Stumvoll, M., Deloukas, P., Donnelly, P. J., Frayling, T. M., Hattersley, A. T., Ripatti, S., Salomaa, V., Pedersen, N. L., Boehm, B. O., Bergman, R. N., Collins, F. S., Mohlke, K. L., Tuomilehto, J., Hansen, Torben, Pedersen, Oluf Borbye, Barroso, I., Lannfelt, L., Ingelsson, E., Lind, L., Lindgren, C. M., Cauchi, S., Froguel, P., Loos, R. J., Balkau, B., Boeing, H., Franks, P. W., Gurrea, A. B., Palli, D., van der Schouw, Y. T., Altshuler, D., Groop, L. C., Langenberg, C., Wareham, N. J., Sijbrands, E., van Duijn, C. M., Florez, J. C., Meigs, J. B., Boerwinkle, E., Gieger, C., Strauch, K., Metspalu, A., Morris, A. D., Palmer, C. N., Hu, F. B., Thorsteinsdottir, U., Stefansson, K., Dupuis, J., Morris, A. P., Boehnke, M., McCarthy, M. I. & Prokopenko, I., 2017, In: Diabetes. 66, 11, p. 2888-2902

Research output: Contribution to journal › Journal article › Research › peer-review

Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion

Skov, L., Schierup, M. H., Danish Pan Genome Consortium, D. P. G. C., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Rasmussen, Simon, Kristiansen, Karsten & Brunak, Søren, 2017, In: PLOS Genetics. 13, 8, p. e1006834

Research output: Contribution to journal › Journal article › Research › peer-review

Archaic adaptive introgression in TBX15/WARS2

Racimo, Fernando, Gokhman, D., Fumagalli, M., Ko, A., Hansen, Torben, Moltke, Ida, Albrechtsen, Anders, Carmel, L., Huerta-Sánchez, E. & Nielsen, Rasmus, 2017, In: Molecular Biology and Evolution. 34, 3, p. 509-524 16 p., msw283.

Research output: Contribution to journal › Journal article › Research › peer-review

Association studies of genetic scores of serum vitamin B12 and folate levels with symptoms of depression and anxiety in two danish population studies

Møllehave, L. T., Skaaby, T., Simonsen, K. S., Thuesen, B. H., Mortensen, Erik Lykke, Sandholt, C. H., Pedersen, Oluf Borbye, Grarup, Niels, Hansen, Torben & Linneberg, Allan René, 2017, In: European Journal of Clinical Nutrition. 71, p. 1054-1060 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

Eriksson, J., Haring, R., Grarup, Niels, Vandenput, L., Wallaschofski, H., Lorentzen, E., Hansen, Torben, Mellström, D., Pedersen, Oluf Borbye, Nauck, M., Lorentzon, M., Nystrup Husemoen, L. L., Völzke, H., Karlsson, M., Baumeister, S. E., Linneberg, Allan René & Ohlsson, C., 2017, In: PloS one. 12, 4, 15 p., e0176277.

Research output: Contribution to journal › Journal article › Research › peer-review

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

de Vries, P. S., Sabater-Lleal, M., Chasman, D. I., Trompet, S., Ahluwalia, T. S., Teumer, A., Kleber, M. E., Chen, M-H., Wang, J. J., Attia, J. R., Marioni, R. E., Steri, M., Weng, L-C., Pool, R., Grossmann, V., Brody, J. A., Venturini, C., Tanaka, T., Rose, L. M., Oldmeadow, C. & 66 others, Mazur, J., Basu, S., Frånberg, M., Yang, Q., Ligthart, S., Hottenga, J. J., Rumley, A., Mulas, A., de Craen, A. J. M., Grotevendt, A., Taylor, K. D., Delgado, G. E., Kifley, A., Lopez, L. M., Berentzen, T. L., Mangino, M., Bandinelli, S., Morrison, A. C., Hamsten, A., Tofler, G., de Maat, M. P. M., Draisma, H. H. M., Lowe, G. D., Zoledziewska, M., Sattar, N., Lackner, K. J., Völker, U., McKnight, B., Huang, J., Holliday, E. G., McEvoy, M. A., Starr, J. M., Hysi, P. G., Hernandez, D. G., Guan, W., Rivadeneira, F., McArdle, W. L., Slagboom, P. E., Zeller, T., Psaty, B. M., Uitterlinden, A. G., de Geus, E. J. C., Stott, D. J., Binder, H., Hofman, A., Franco, O. H., Rotter, J. I., Ferrucci, L., Spector, T. D., Deary, I. J., März, W., Greinacher, A., Wild, P. S., Cucca, F., Boomsma, D. I., Watkins, H., Tang, W., Ridker, P. M., Jukema, J. W., Scott, R. J., Mitchell, P., Hansen, Torben, O'Donnell, C. J., Smith, N. L., Strachan, D. P. & Dehghan, A., 2017, In: PLOS ONE. 12, 1, 22 p., e0167742.

Research output: Contribution to journal › Journal article › Research › peer-review

Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study

Ding, M., Huang, T., Bergholdt, H. K. M., Sørensen, Thorkild I.A., Linneberg, Allan René, Sandholt, C. H., Pedersen, Oluf Borbye, Hansen, Torben, Kilpeläinen, Tuomas O., CHARGE Consortium, C. C., Nordestgaard, Børge, Ellervik, Christina, Qi, L. & Mendelian Randomization of Dairy Consumption Working Group, M. R. O. D. C. W. G., 2017, In: The BMJ. 356, 10 p., j1000.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of the interaction between diet composition and the PPM1K genetic variant on insulin resistance and β cell function markers during weight loss: results from the Nutrient Gene Interactions in Human Obesity: implications for dietary guidelines (NUGENOB) randomized trial

Goni, L., Qi, L., Cuervo, M., Milagro, F. I., Saris, W. H., Macdonald, I. A., Langin, D., Astrup, A., Arner, P., Oppert, J. M., Svendstrup, M., Blaak, E., Sørensen, Thorkild I.A., Hansen, Torben & Martinez, J. A., 2017, In: American Journal of Clinical Nutrition. 106, 3, p. 902-908 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Estimates of insulin sensitivity and β-cell function in children and adolescents with and without components of the metabolic syndrome

Frithioff-Bøjsøe, C., Trier, C., Fonvig, Cilius Esmann, Nissen, A., Kloppenborg, J. T., Mollerup, P. M., Bjerrum, P. J., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2017, In: Pediatric Endocrinology, Diabetes and Metabolism. 23, 3, p. 122-129 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans

Søberg, S., Sandholt, C. H., Z. Jespersen, N., Toft, U., L. Madsen, A., Holstein-Rønsbo, Stephanie, Grevengoed, Trisha Jean, Christensen, Karl Bang, Bredie, Wender, Potthoff, M. J., P. J. Solomon, T., Schéele, Camilla Charlotte Nielsen, Linneberg, Allan René, Jørgensen, T., Pedersen, Oluf Borbye, Hansen, Torben, Gillum, M. P. & Grarup, Niels, 2017, In: Cell Metabolism. 25, 5, p. 1045-1053 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function

Jorgensen, S., Have, C. T., Underwood, C. R., Johansen, L. D., Wellendorph, Petrine, Gjesing, A. P., Jorgensen, C. V., Quan, S., Rui, G., Inoue, A., Linneberg, Allan René, Grarup, Niels, Jun, W., Pedersen, Oluf Borbye, Hansen, Torben & Bräuner, Hans, 2017, In: The Journal of Biological Chemistry. 292, 4, p. 1524-1534 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Heterogeneity in glucose response curves during an oral glucose tolerance test and associated cardiometabolic risk

Hulman, A., Simmons, R. K., Vistisen, D., Tabák, A. G., Dekker, J. M., Alssema, M., Rutters, F., Koopman, A. D. M., Solomon, T. P. J., Kirwan, J. P., Hansen, Torben, Jonsson, Anna Elisabet, Gjesing, A. M. P., Eiberg, Hans Rudolf Lytchoff, Astrup, A., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A., Witte, D. & Færch, K., 2017, In: Endocrine. 55, 2, p. 427-434 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus

Gjesing, A. M. P., Rui, G., Lauenborg, J., Have, C. T., Hollensted, M., Andersson, E., Grarup, Niels, Sun, J., Quan, S., Brandslund, I., Damm, Peter, Pedersen, Oluf Borbye, Wang, J. & Hansen, Torben, 2017, In: Endocrine Research. 1, 6, p. 681-690 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Higher intake of fish and fat is associated with lower plasma s-adenosylhomocysteine: a cross-sectional study

Lind, M. V., Lauritzen, Lotte, Pedersen, Oluf Borbye, drb459, drb459, Stark, K. D., Hansen, Torben, Ross, A. B. & Kristensen, M. B., 2017, In: Nutrition Research. 46, p. 78-87 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium

Skaaby, T., Taylor, A. E., Jacobsen, R. K., Paternoster, L., Thuesen, B. H., Ahluwalia, T. S., Larsen, S. C., Zhou, A., Wong, A., Gabrielsen, M. E., Bjørngaard, J. H., Flexeder, C., Männistö, S., Hardy, R., Kuh, D., Barry, S. J., Tang Møllehave, L., Cerqueira, C., Friedrich, N., Bonten, T. N. & 34 others, Noordam, R., Mook-Kanamori, D. O., Taube, C., Jessen, L. E., McConnachie, A., Sattar, N., Upton, M. N., McSharry, C., Bønnelykke, Klaus, Bisgaard, H., Schulz, H., Strauch, K., Meitinger, T., Peters, A., Grallert, H., Nohr, E. A., Kivimaki, M., Kumari, M., Völker, U., Nauck, M., Völzke, H., Power, C., Hyppönen, E., Hansen, Torben, Jørgensen, T., Pedersen, Oluf Borbye, Salomaa, V., Grarup, Niels, Langhammer, A., Romundstad, P. R., Skorpen, F., Kaprio, J., R Munafò, M. & Linneberg, Allan René, 2017, In: Scientific Reports. 7, 1, 9 p., 2224.

Research output: Contribution to journal › Journal article › Research › peer-review

Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia

Hyltén-Cavallius, L., Iepsen, E. W., Albrechtsen, Nicolai Jacob Wewer, Svendstrup, M., Lubberding, Anniek Frederike, Hartmann, Bolette, Jespersen, Thomas, Linneberg, Allan René, Christiansen, M., drb459, drb459, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K., Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Circulation. 135, 18, p. 1705-1719 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Self-Reported Versus Accelerometer-Assessed Daily Physical Activity in Childhood Obesity Treatment

Schnurr, T. M., Bech, B., Haarmark Nielsen, T. R., Andersen, I. G., Hjorth, Mads Fiil, Aadahl, Mette, Fonvig, Cilius Esmann, Hansen, Torben & Holm, Jens-Christian, 2017, In: Perceptual and Motor Skills. 124, 4, p. 795-811 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Sequencing and de novo assembly of 150 genomes from Denmark as a population reference

Sørensen, L. M., Jensen, J. M., Petersen, B., Sibbesen, J. A., Liu, S., Villesen, P., Skov, L., Belling, K. G., Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R., Ye, W., Rao, J., Guo, X. & 39 others, Sun, J., Cao, H., Ye, C., van Beusekom, J., Espeseth, T., Flindt, E., Friborg, R. M., Halager, A. E., Le Hellard, S., Hultman, C. M., Lescai, F., Li, S., Lund, O., Løngren, P., Mailund, T., Matey-Hernandez, M. L., Mors, O., Pedersen, C. N. S., Sicheritz-Pontén, T., Sullivan, P., Syed, A., Westergaard, David, Yadav, R., Li, N., Xu, X., Hansen, Torben, Krogh, Anders, Bolund, L., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Gupta, R., Rasmussen, Simon, Besenbacher, S., Børglum, A. D., Wang, J., Eiberg, Hans Rudolf Lytchoff, Kristiansen, Karsten, Brunak, Søren & Schierup, M. H., 2017, In: Nature. 548, 7665, p. 87-91 5 p.

Research output: Contribution to journal › Letter › Research › peer-review

The effect of smoking on the urinary excretion of 8-oxodG and 8-oxoGuo in patients with type 2 diabetes

Sørensen, A., Kjær, L. K., Petersen, K. M., Henriksen, T., Cejvanovic, V., Pedersen, Oluf Borbye, Hansen, Torben, Christensen, C. K., Brandslund, I. & Poulsen, Henrik Enghusen, 2017, In: Scandinavian Journal of Clinical & Laboratory Investigation. 77, 4, p. 253-258 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB

pjx571, pjx571, Lundgren, Jens, Albrechtsen, Nicolai Jacob Wewer, Mahendran, Y., Iepsen, E. P. W., Finocchietto, P., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Obesity Science & Practice. 3, 4, p. 425-433 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Urinary metabolomics reveals glycemic and coffee associated signatures of thyroid function in two population-based cohorts

Friedrich, N., Pietzner, M., Cannet, C., Thuesen, B. H., Hansen, Torben, Wallaschofski, H., Grarup, Niels, Skaaby, T., Budde, K., Pedersen, Oluf Borbye, Nauck, M. & Linneberg, Allan René, 2017, In: PLOS ONE. 12, 3, 17 p., e0173078.

Research output: Contribution to journal › Journal article › Research › peer-review

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

Schmidt, A. F., Swerdlow, D. I., Holmes, M. V., Patel, R. S., Fairhurst-Hunter, Z., Lyall, D. M., Hartwig, F. P., Horta, B. L., Hyppönen, E., Power, C., Moldovan, M., van Iperen, E., Hovingh, G. K., Demuth, I., Norman, K., Steinhagen-Thiessen, E., Demuth, J., Bertram, L., Liu, T., Coassin, S. & 31 others, Willeit, J., Kiechl, S., Willeit, K., Mason, D., Wright, J., Morris, R., Wanamethee, G., Whincup, P., Ben-Shlomo, Y., McLachlan, S., Price, J. F., Kivimaki, M., Welch, C., Sanchez-Galvez, A., Marques-Vidal, P., Nicolaides, A., Panayiotou, A. G., Onland-Moret, N. C., van der Schouw, Y. T., Matullo, G., Fiorito, G., Guarrera, S., Sacerdote, C., Wareham, N. J., Langenberg, C., Scott, R., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René & LifeLines Cohort study group, L. C. S. G., Feb 2017, In: The Lancet Diabetes & Endocrinology. 5, 2, p. 97–105

Research output: Contribution to journal › Journal article › Research › peer-review

Cohort description: The Danish study of Functional Disorders

Dantoft, T. M., Ebstrup, J. F., Linneberg, Allan René, Skovbjerg, S., Madsen, A. L., Mehlsen, J., Brinth, L., Eplov, L. F., Carstensen, T. W., Schroder, A., Fink, P. K., Mortensen, Erik Lykke, Hansen, Torben, Pedersen, Oluf Borbye & Jørgensen, T., Feb 2017, In: Clinical Epidemiology. 9, p. 127-139 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic determinants of serum vitamin B12 and their relation to body mass index

Allin, K. H., Friedrich, N., Pietzner, M., Grarup, Niels, Thuesen, B. H., Linneberg, Allan René, Pisinger, C., Hansen, Torben, Pedersen, Oluf Borbye & Sandholt, C. H., Feb 2017, In: European Journal of Epidemiology. 32, 2, p. 125–134

Research output: Contribution to journal › Journal article › Research › peer-review

The effect of an extreme and prolonged population bottleneck on patterns of deleterious variation: insights from the Greenlandic Inuit

Pedersen, C. T., Lohmueller, K. E., Grarup, Niels, Bjerregaard, P., Hansen, Torben, Siegismund, Hans Redlef, Moltke, Ida & Albrechtsen, Anders, Feb 2017, In: Genetics. 205, 2, p. 787-801 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Rare and low-frequency coding variants alter human adult height

Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T. & 31 others, Locke, A. E., Masca, N. G. D., Ng, M. C. Y., Mudgal, P., Rivas, M. A., Vedantam, S., Mahajan, A., Guo, X., Abecasis, G., Aben, K. K., Allin, K. H., Appel, E. V., Bang, L. E., Benn, Marianne, Bork-Jensen, J., Frikke-Schmidt, Ruth, Grarup, Niels, Hansen, Torben, Hollensted, M., Jensen, G. B., Jørgensen, M. E., Jørgensen, T., Kamstrup, P. R., Linneberg, Allan René, Nielsen, S. F., Nordestgaard, Børge, Pedersen, Oluf Borbye, Tybjærg-Hansen, Anne, drb459, drb459, Pers, Tune H & EPIC-InterAct Consortium, E. C., 9 Feb 2017, In: Nature. 542, 7640, p. 186-190 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels

Mahendran, Y., Jonsson, Anna Elisabet, Have, C. T., Allin, K. H., Witte, D. R., Jørgensen, M. E., Grarup, Niels, Pedersen, Oluf Borbye, Kilpeläinen, Tuomas O. & Hansen, Torben, 10 Feb 2017, In: Diabetologia. 60, 5, p. 873-878 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Homozygous carriers of the TCF7L2 rs7903146 T-allele show altered postprandial response in triglycerides and triglyceride-rich lipoproteins

pjx571, pjx571, Hansen, T. H., Mahendran, Y., Pyl, P., Galijatovic, E. A. A., Jonsson, Anna Elisabet, Gjesing, A., Linneberg, Allan René, Jørgensen, T., Hansen, Torben & drb459, drb459, 21 Feb 2017, In: Scientific Reports. 7, 8 p., 43128.

Research output: Contribution to journal › Journal article › Research › peer-review

Carriers of a VEGFA enhancer polymorphism selectively binding CHOP/DDIT3 are predisposed to increased circulating levels of thyroid-stimulating hormone

Ahluwalia, Tarun Veer Singh, Troelsen, J. T., Balslev-Harder, M., Bork-Jensen, J., Thuesen, B. H., Cerqueira, C., Linneberg, Allan René, Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben & Dalgaard, L. T., Mar 2017, In: Journal of Medical Genetics. 54, 3, p. 166-175 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Objective assessment of dietary patterns by use of metabolic phenotyping: a randomised, controlled, crossover trial

Garcia-Perez, I., Posma, J. M., Gibson, R., Chambers, E. S., Hansen, T. H., drb459, drb459, Hansen, Torben, Beckmann, M., Pedersen, Oluf Borbye, Elliott, P., Stamler, J., Nicholson, J. K., Draper, J., Mathers, J. C., Holmes, E. & Frost, G., Mar 2017, In: The Lancet Diabetes & Endocrinology. 5, 3, p. 184-195 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Subclinical Hypothyroidism in Danish Lean and Obese Children and Adolescents

Dahl, M., Ohrt, J. D., Fonvig, C. E., Kloppenborg, J. T., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 1 Mar 2017, In: JCRPE Journal of Clinical Research in Pediatric Endocrinology. 9, 1, p. 8-16 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults

Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 34 others, Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, Johanne Marie, Kleber, M. E., Hollensted, M., Aadahl, Mette, Færch, K., Grarup, Niels, drb459, drb459, Sørensen, Thorkild I.A., Linneberg, Allan René, Hansen, Torben, Pedersen, Oluf Borbye, Loos, Ruth, Kilpeläinen, Tuomas O., CHARGE Consortium, C. C., EPIC-InterAct Consortium, E. C. & PAGE Consortium, P. C., 1 Apr 2017, In: PLOS Genetics. 13, 4, e1006528.

Research output: Contribution to journal › Journal article › Research › peer-review

Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression

Rocha, N., Bulger, D. A., Frontini, A., Titheradge, H., Gribsholt, S. B., Knox, R., Page, M., Harris, J., Payne, F., Adams, C., Sleigh, A., Crawford, J., Gjesing, A. P., Bork-Jensen, J., Pedersen, O., Barroso, I., Hansen, T., Cox, H., Reilly, M., Rossor, A. & 11 others, Brown, R. J., Taylor, S. I., McHale, D., Armstrong, M., Oral, E. A., Saudek, V., O'Rahilly, S., Maher, E. R., Richelsen, B., Savage, D. B. & Semple, R. K., 19 Apr 2017, In: eLife. 6, 27 p., e23813.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K. L., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A. & 297 others, Renström, F., Wu, J. C., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg-Gresham, J. L., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Neergaard Harder, M., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, Johanne Marie, Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-Nurasyid, M., Navarro, P., Pérusse, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stančáková, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., van der Laan, S. W., van der Most, P. J., van Vliet-Ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Hua Zhao, J., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E. P., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., de Borst, G. J., De Craen, A. J. M., de Geus, E. J. C., Dedoussis, G., Delgado, G. E., den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, Niels, Haitjema, S., Hallmans, G., Hamsten, A., Hansen, Torben, Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D., Hindorff, L. A., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Jan Hottenga, J., Huang, J., Hung, J., Hutri-Kähönen, N., Ingelsson, E., James, A. L., Jansson, J., Jarvelin, M. R., Jhun, M. A., Jørgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaløy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, Allan René, Lobbens, S., Loh, M., Lorentzon, M., Luben, R., Lubke, G., Ludolph-Donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-Vidal, P., Martin, N. G., Mckenzie, C. A., McKnight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A. B., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-Torvik, L. J., Rawal, R., Rice, T. K., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Chen, Y., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., Faire, U. D., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-Larsen, P., Grabe, H. J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Wouter Jukema, J., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Marchand, L. L., März, W., McCarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, Oluf Borbye, Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sørensen, Thorkild I.A., Strauch, K., Tiemeier, H., Tremoli, E., van der Harst, P., drb459, drb459, Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J. L., Loos, R. J. F., Kilpeläinen, Tuomas O., Liu, C., Borecki, I. B., North, K. E. & Cupples, L. A., 26 Apr 2017, In: Nature Communications. 8, 19 p., 14977.

Research output: Contribution to journal › Journal article › Research › peer-review

Dyslipidemia and reference values for fasting plasma lipid concentrations in Danish/North-European White children and adolescents

Nielsen, T. R. H., Lausten-Thomsen, U., Fonvig, Cilius Esmann, Bøjsøe, C., Pedersen, L., Bratholm, P. S., Hansen, Torben, Pedersen, Oluf Borbye & Holm, Jens-Christian, 28 Apr 2017, In: B M C Pediatrics. 17, 11 p., 116.

Research output: Contribution to journal › Journal article › Research › peer-review

Numerous Brugada syndrome-associated genetic variants have no effect on J-point elevation, syncope susceptibility, malignant cardiac arrhythmia, and all-cause mortality

Ghouse, Jonas, Have, C. T., Skov, M. W., Andreasen, Laura Korsholm, Ahlberg, G., Nielsen, J. B., Skaaby, T., Olesen, Søren-Peter, Grarup, Niels, Linneberg, Allan René, Pedersen, Oluf Borbye, drb459, drb459, Haunsø, Stig, Svendsen, Jesper Hastrup, Hansen, Torben, Kanters, Jørgen K. & Olesen, Morten Steen Salling, May 2017, In: Genetics In Medicine. 19, 5, p. 521-528 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Reference intervals for C-peptide and insulin derived from a general adult Danish population

Larsen, P. B., Linneberg, Allan René, Hansen, Torben & Friis-Hansen, L. J., May 2017, In: Clinical Biochemistry. 50, 7-8, p. 408-413

Research output: Contribution to journal › Journal article › Research › peer-review

Corrigendum: Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, M., Kristiansen, K., Voigt, A. Y., Vestergaard, H., Hercog, R., Costea, P. I., Kultima, J. R., Li, J., Jørgensen, T., Levenez, F. & 10 others, Doré, J., Nielsen, H. B., Brunak, Søren, Raes, J., Hansen, Torben, Wang, J., Ehrlich, S. D., Bork, P., Pedersen, Oluf Borbye & MetaHIT consortium, M. C., 3 May 2017, In: Nature. 545, 116, 1 p., 22318.

Research output: Contribution to journal › Comment/debate › Research

Reference values for fasting serum resistin in healthy children and adolescents

Lausten-Thomsen, U., Christiansen, M., Hedley, P. L., Nielsen, T. R. H., Fonvig, Cilius Esmann, Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, Jun 2017, In: Clinica Chimica Acta. 469, p. 161-165 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Selection in Europeans on fatty acid desaturases associated with dietary changes

Buckley, M. T., Racimo, Fernando, Allentoft, Morten Erik, Jensen, M. K., Jonsson, Anna Elisabet, Huang, H., Hormozdiari, F., Sikora, Martin, Marnetto, D., Eskin, E., Jørgensen, M. E., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Kraft, P., Willerslev, Eske & Nielsen, Rasmus, Jun 2017, In: Molecular Biology and Evolution. 34, 6, p. 1307-1318 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Discovery of novel heart rate-associated loci using the Exome Chip

van den Berg, M. E., Warren, H. R., Cabrera, C. P., Verweij, N., Mifsud, B., Haessler, J., Bihlmeyer, N. A., Fu, Y-P., Weiss, S., Lin, H. J., Grarup, N., Li-Gao, R., Pistis, G., Shah, N., Brody, J. A., Müller-Nurasyid, M., Lin, H., Mei, H., Smith, A. V., Lyytikäinen, L-P. & 101 others, Hall, L. M., van Setten, J., Trompet, S., Prins, B. P., Isaacs, A., Radmanesh, F., Marten, J., Entwistle, A., Kors, J. A., Silva, C. T., Alonso, A., Bis, J. C., de Boer, R. A., de Haan, H. G., de Mutsert, R., Dedoussis, G., Dominiczak, A. F., Doney, A. S. F., Ellinor, P. T., Eppinga, R. N., Felix, S. B., Guo, X., Hagemeijer, Y., Hansen, Torben, Harris, T. B., Heckbert, S. R., Huang, P. L., Hwang, S., Kähönen, M., Kanters, Jørgen K., Kolcic, I., Launer, L. J., Li, M., Yao, X. J., Linneberg, Allan René, Liu, S., Macfarlane, P. W., Mangino, M., Morris, A. D., Mulas, A., Murray, A. D., Nelson, C. P., Orrù, M., Padmanabhan, S., Peters, A., Porteous, D. J., Poulter, N., Psaty, B. M., Qi, L., Raitakari, O. T., Rivadeneira, F., Roselli, C., Rudan, I., Sattar, N., Sever, P., Sinner, M. F., Soliman, E. Z., Spector, T. D., Stanton, A. V., Stirrups, K. E., Taylor, K. D., Tobin, M. D., Uitterlinden, A., Vaartjes, I., Hoes, A. W., van der Meer, P., Völker, U., Waldenberger, M., Xie, Z., Zoledziewska, M., Tinker, A., Polasek, O., Rosand, J., Jamshidi, Y., van Duijn, C. M., Zeggini, E., Jukema, J. W., Asselbergs, F. W., Samani, N. J., Lehtimäki, T., Gudnason, V., Wilson, J., Lubitz, S. A., Kääb, S., Sotoodehnia, N., Caulfield, M. J., Palmer, C. N. A., Sanna, S., Mook-Kanamori, D. O., Deloukas, P., Pedersen, Oluf Borbye, Rotter, J. I., Dörr, M., O'Donnell, C. J., Hayward, C., Arking, D. E., Kooperberg, C., van der Harst, P., Eijgelsheim, M., Stricker, B. H. C. & Munroe, P. B., 15 Jun 2017, In: Human Molecular Genetics. 26, 12, p. 2346-2363 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

Willems, S. M., et al., E. A., Grarup, Niels, Linneberg, Allan René, Schnurr, T. M., Pedersen, Oluf Borbye, GEFOS Any-Type of Fracture Consortium, G. A. O. F. C. & Hansen, Torben, 12 Jul 2017, In: Nature Communications. 8, 12 p., 16015.

Research output: Contribution to journal › Journal article › Research › peer-review

Glucose ingestion causes cardiac repolarization disturbances in type 1 long QT syndrome patients and healthy subjects

Hyltén-Cavallius, L., Iepsen, E. W., Christiansen, M., Graff, C., Linneberg, Allan René, Pedersen, Oluf Borbye, Holst, Jens Juul, Hansen, Torben, Torekov, Signe Sørensen & Kanters, Jørgen K., Aug 2017, In: Heart Rhythm. 14, 8, p. 1165-1170 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Ponderal index at birth associates with later risk of gestational diabetes mellitus

Crusell, Mie Korslund Wiinblad, Damm, Peter, Hansen, Torben, Pedersen, Oluf Borbye, Glümer, C., Vaag, Allan & Lauenborg, J., Aug 2017, In: Archives of Gynecology and Obstetrics. 296, 2, p. 249-256 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Alcohol consumption and its interaction with adiposity-associated genetic variants in relation to subsequent changes in waist circumference and body weight

Rohde, J. F., Ängquist, Lars, Larsen, S. C., Tolstrup, J. S., Husemoen, L. L. N., Linneberg, Allan René, Toft, Ulla Marie Nørgaard, Overvad, K., Halkjær, J., Tjønneland, A., Hansen, Torben, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Heitmann, Berit, 25 Aug 2017, In: Nutrition Journal. 16, 11 p., 51.

Research output: Contribution to journal › Journal article › Research › peer-review

Assembly and analysis of 100 full MHC haplotypes from the Danish population

Jensen, J. M., Villesen, P., Friborg, R. M., Mailund, T., Besenbacher, S., Sørensen, L. M., Petersen, B., Sibbesen, J. A., Liu, S., Skov, L., Belling, K. G., Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R. & 39 others, Ye, W., Rao, J., Guo, X., Sun, J., Cao, H., Ye, C., Beusekom, J. V., Espeseth, T., Flindt, E., Halager, A. E., Hellard, S. L., Hultman, C. M., Lescai, F., Li, S., Lund, O., Løngren, P., Matey-Hernandez, M. L., Mors, O., Pedersen, C. N. S., Sicheritz-Pontén, T., Sullivan, P., Syed, A., Westergaard, D., Yadav, R., Li, N., Xu, X., Hansen, Torben, Bolund, L., Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Gupta, R., Rasmussen, Simon, Børglum, A. D., Wang, J., Eiberg, Hans Rudolf Lytchoff, Kristiansen, Karsten, Brunak, Søren & Schierup, M. H., Sep 2017, In: Genome Research. 27, 9, p. 1597-1607 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cell-Free DNA in Metastatic Colorectal Cancer: A Systematic Review and Meta-Analysis

Spindler, K. G., Boysen, A. K., Pallisgård, N., Johansen, Julia Sidenius, Tabernero, J., Sørensen, M. M., Jensen, B. V., Hansen, Torben, Sefrioui, D., Andersen, R. F., Brandslund, I. & Jakobsen, A., Sep 2017, In: Oncologist. 22, 9, p. 1049-1055 7 p.

Research output: Contribution to journal › Review › Research › peer-review

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

Kraja, A. T., Cook, J. P., Warren, H. R., Surendran, P., Liu, C., Evangelou, E., Manning, A. K., Grarup, N., Drenos, F., Sim, X., Smith, A. V., Amin, N., Blakemore, A. I. F., Bork-Jensen, J., Brandslund, I., Farmaki, A. E., Fava, C., Ferreira, T., Herzig, K. H., Giri, A. & 31 others, Giulianini, F., Grove, M. L., Guo, X., Harris, S. E., Have, C. T., Havulinna, A. S., Zhang, H., Jørgensen, M. E., Käräjämäki, A. M., Kooperberg, C., Linneberg, Allan René, Little, L., Liu, Y., Bonnycastle, L. L., Lu, Y., Mägi, R., Mahajan, A., Malerba, G., Marioni, R. E., Mei, H., Menni, C., Morrison, A. C., Padmanabhan, S., Palmas, W., Poveda, A., Rauramaa, R., Rayner, N. W., Riaz, M., Hansen, Torben, Pedersen, Oluf Borbye & behalf of the CHARGE EXOME BP, CHD Exome+, Exome BP, GoT2D:T2DGenes Consortia, The UK Biobank Cardio-Metabolic Traits Consortium Blood Pressure Working Group, B. O. T. C. E. B. C. E. E. B. G. C. T. U. B. C. T. C. B. P. W. G., Oct 2017, In: Circulation: Cardiovascular Genetics. 10, 5, 9 p., e001778.

Research output: Contribution to journal › Journal article › Research › peer-review

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475000 Individuals

Kraja, A. T., Cook, J. P., Warren, H. R., Surendran, P., Liu, C., Evangelou, E., Manning, A. K., Grarup, N., Drenos, F., Sim, X., Smith, A. V., Amin, N., Blakemore, A. I. F., Bork-Jensen, J., Brandslund, I., Farmaki, A-E., Fava, C., Ferreira, T., Herzig, K-H., Giri, A. & 122 others, Giulianini, F., Grove, M. L., Guo, X., Harris, S. E., Have, C. T., Havulinna, A. S., Zhang, H., Jørgensen, M. E., Karajamaki, A., Kooperberg, C., Linneberg, Allan René, Little, L., Liu, Y., Bonnycastle, L. L., Lu, Y., Magi, R., Mahajan, A., Malerba, G., Marioni, R. E., Mei, H., Menni, C., Morrison, A. C., Padmanabhan, S., Palmas, W., Poveda, A., Rauramaa, R., Rayner, N. W., Riaz, M., Rice, K., Richard, M. A., Smith, J. A., Southam, L., Stancakova, A., Stirrups, K. E., Tragante, V., Tuomi, T., Tzoulald, I., V Varga, Tibor, Weiss, S., Yiorkas, A. M., Young, R., Zhang, W., Barnes, M. R., Cabrera, C. P., Gao, H., Boehnke, M., Boerwinkle, E., Chambers, J. C., Connell, J. M., Christensen, C. K., de Boer, R. A., Deary, I. J., Dedoussis, G., Deloukas, P., Dominiczak, A. F., Dorr, M., Joehanes, R., Edwards, T. L., Esko, T., Fornage, M., Franceschini, N., Franks, P. W., Gambaro, G., Groop, L., Hallmans, G., Hansen, Torben, Hayward, C., Heikki, O., Ingelsson, E., Tuomilehto, J., Jarvelin, M., Kardia, S. L. R., Karpe, F., Kooner, J. S., Lakka, T. A., Langenberg, C., Lind, L., Loos, Ruth, Laakso, M., McCarthy, M. I., Melander, O., Mohlke, K. L., Moris, A. P., Palmer, C. N. A., Pedersen, Oluf Borbye, Polasek, O., Poulter, N. R., Province, M. A., Psaty, B. M., Ridker, P. M., Rotter, J. I., Rudan, I., Salomaa, V., Samani, N. J., Sever, P. J., Skaaby, T., Stafford, J. M., Starr, J. M., van der Harst, P., van der Meer, P., van Duijn, C. M., Vergnaud, A., Gudnason, V., Wareham, N. J., Wilson, J. G., Willer, C. J., Witte, D. R., Zeggini, E., Saleheen, D., Butterworth, A. S., Danesh, J., Asselbergs, F. W., Wain, L. V., Ehret, G. B., Chasman, D. I., Caulfield, M. J., Elliott, P., Lindgren, C. M., Levy, D., Newton-Cheh, C., Munroe, P. B. & Howson, J. M. M., Oct 2017, In: Circulation: Cardiovascular Genetics. 10, 5

Research output: Contribution to journal › Journal article › Research › peer-review

Environmental spread of microbes impacts the development of metabolic phenotypes in mice transplanted with microbial communities from humans

Zhang, L., Bahl, M. I., Roager, Henrik Munch, Fonvig, C. E., Hellgren, L. I., Frandsen, H. L., Pedersen, Oluf Borbye, Holm, Jens-Christian, Hansen, Torben & Licht, T. R., 18 Nov 2017, In: The ISME Journal. 11, p. 676-690 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 243 others, Teslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimäki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S., Gjesing, A. M. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, Johanne Marie, Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., DePristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., Hrabé de Angelis, M., Maguire, J., Neale, B. M., Poplin, R., Purcell, S., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., V Varga, Tibor, Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Hale, D. E., Fowler, S. P., Arya, R., DeFronzo, R. A., Abboud, H. E., Syvänen, A., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Mägi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Müller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J., Han, B., Käräjämäki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., Melander, O., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., Liu, J., Khor, C., Chia, K. S., Lim, W. Y., Cheng, C., Chan, E., Tai, E. S., Aung, T., Linneberg, Allan René, Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Kravic, J., Jørgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Owen, K. R., Farmer, A. J., Frayling, T. M., O'Rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stančáková, A., Barroso, I., Bharadwaj, D., Chan, J., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Kesaniemi, Y. A., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jørgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Kuusisto, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. & Lindgren, C. M., Dec 2017, In: Diabetes. 66, p. 2019-2032 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review