Hansen Group

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  1. 2014
  2. Published

    Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium: Diabetologia

    Koivula, R., Heggie, A., Barnett, A., Cederberg, H., Hansen, T. H., Koopman, A., Ridderstråle, M., Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M., Perry, M., Rauh, S., Siloaho, M., Teare, H. A., Thorand, B., Bell, J., Brunak, S., Frost, G. & 13 others, Jablonka, B., Mari, A., McDonald, T., Dekker, J., Hansen, Torben, Hattersley, A., Laakso, M., Pedersen, Oluf Borbye, Koivisto, V., Ruetten, H., Walker, M., Pearson, E. & Franks, P., 2014, In: Diabetologia. 57, 6, p. 1-11 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Effects of body size and change in body size from infancy through childhood on body mass index in adulthood

    Bjerregaard, L. G., Rasmussen, K. M., Michaelsen, Kim F., Skytthe, A., Mortensen, Erik Lykke, Baker, J. L. & Sørensen, Thorkild I.A., 2014, In: International Journal of Obesity. 38, 10, p. 1305-1311 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model

    Gao, R., Liu, Y., Gjesing, A. M. P., Hollensted, M., Wan, X., He, S., Pedersen, Oluf Borbye, Yi, X., Wang, J. & Hansen, Torben, 2014, In: B M C Genetics. 15, 9 p., 13.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Functional Screening Identifies miRNAs Influencing Apoptosis and Proliferation in Colorectal Cancer

    Christensen, L. L., Holm, A., Rantala, J., Kallioniemi, O., Rasmussen, M. H., Ostenfeld, M. S., Dagnaes-Hansen, F., Oster, B., Schepeler, T., Tobiasen, H., Thorsen, K., Sieber, O. M., Gibbs, P., Lamy, P., Hansen, T. F., Jakobsen, A., Riising, E. M., Helin, K., Lubinski, J., Hagemann-Madsen, R. & 3 others, Laurberg, S., Orntoft, T. F. & Andersen, C. L., 2014, In: PLOS ONE. 9, 6, p. e96767

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study

    Langenberg, C., Sharp, S. J., Franks, P. W., Scott, R. A., Deloukas, P., Forouhi, N. G., Froguel, P., Groop, L. C., Hansen, T., Palla, L., Pedersen, O., Schulze, M. B., Tormo, M-J., Wheeler, E., Agnoli, C., Arriola, L., Barricarte, A., Boeing, H., Clarke, G. M., Clavel-Chapelon, F. & 27 others, Duell, E. J., Fagherazzi, G., Kaaks, R., Kerrison, N. D., Key, T. J., Khaw, K. T., Kröger, J., Lajous, M., Morris, A. P., Navarro, C., Nilsson, P. M., Overvad, K., Palli, D., Panico, S., Quirós, J. R., Rolandsson, O., Sacerdote, C., Sánchez, M., Slimani, N., Spijkerman, A. M. W., Tumino, R., van der A, D. L., van der Schouw, Y. T., Barroso, I., McCarthy, M. I., Riboli, E. & Wareham, N. J., 2014, In: P L o S Medicine (Print). 11, 5, 14 p., e1001647.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

    Nielsen, H. B., Almeida, M., Juncker, A., Rasmussen, S., Li, J., Sunagawa, S., Plichta, D. R., Gautier, L., Pedersen, A. G., Le Chatelier, E., Pelletier, E., Bonde, I., Nielsen, T., Manichanh, C., Arumugam, M., Batto, J-M., dos Santos, M. B. Q., Blom, N., Borruel, N., Burgdorf, K. S. & 31 others, Boumezbeur, F., Casellas, F., Doré, J., Dworzynski, P., Guarner, F., Hansen, Torben, Hildebrand, F., Kaas, R. S., Kennedy, S., Kristiansen, Karsten, Kultima, J. R., Léonard, P., Levenez, F., Lund, O., Moumen, B., Le Paslier, D., Pons, N., Pedersen, Oluf Borbye, Prifti, E., Qin, J., Raes, J., Sørensen, Søren Johannes, Tap, J., Tims, S., Ussery, D., Yamada, T., Renault, P., Sicheritz-Pontén, T., Bork, P., Wang, J. & MetaHIT Consortium, M. C., 2014, In: Nature Biotechnology. 32, 8, p. 822–828 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Identification of Mislabeled Samples and Sample Mix-ups in Genotype Data using Barcode Genotypes

    Have, C. T., Appel, E. V. R., Grarup, Niels, Hansen, Torben & Bork-Jensen, J., 2014, In: International Journal of Bioscience, Biochemistry and Bioinformatics. 4, 5, p. 355-360 5 p., 370.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Interaction between genetic predisposition to adiposity and dietary protein in relation to subsequent change in body weight and waist circumference

    Ankarfeldt, Mikkel Zöllner, Larsen, S. C., Ängquist, Lars, Husemoen, L. L. N., Roswall, N., Overvad, K., Jakobsen, M. U., Halkjær, J., Tjønneland, A., Linneberg, Allan René, Toft, Ulla Marie Nørgaard, Hansen, Torben, Pedersen, Oluf Borbye, Heitmann, Berit, Astrup, A. & Sørensen, Thorkild I.A., 2014, In: P L o S One. 9, 10, 10 p., e110890.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Pleiotropic genes for metabolic syndrome and inflammation

    Kraja, A. T., Chasman, D. I., North, K. E., Reiner, A. P., Yanek, L. R., Oskari Kilpeläinen, T., Smith, J. A., Dehghan, A., Dupuis, J., Johnson, A. D., Feitosa, M. F., Tekola-Ayele, F., Chu, A. Y., Nolte, I. M., Dastani, Z., Morris, A., Pendergrass, S. A., Sun, Y. V., Ritchie, M. D., Vaez, A. & 31 others, Lin, H., Ligthart, S., Marullo, L., Rohde, R., Shao, Y., Ziegler, M. A., Im, H. K., Schnabel, R. B., Jørgensen, T., Jørgensen, M. E., Hansen, Torben, Pedersen, Oluf Borbye, Stolk, R. P., Snieder, H., Hofman, A., Uitterlinden, A. G., Franco, O. H., Ikram, M. A., Richards, J. B., Rotimi, C., Wilson, J. G., Lange, L., Ganesh, S. K., Nalls, M., Rasmussen-Torvik, L. J., Pankow, J. S., Coresh, J., Tang, W., Linda Kao, W. H., Boerwinkle, E. & Cross Consortia Pleiotropy (XC-Pleiotropy) Group, C. C. P. (. G., 2014, In: Molecular Genetics and Metabolism. 112, 4, p. 317-38 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Two randomized cross-over trials assessing the impact of dietary gluten or wholegrain on the gut microbiome and host metabolic health

    Ibrügger, S., Gøbel, R. J., drb459, drb459, Licht, T. R., Frøkiær, Hanne, Linneberg, Allan René, Hansen, Torben, Gupta, R., Pedersen, Oluf Borbye, Kristensen, M. B. & Lauritzen, Lotte, 2014, In: Journal of Clinical Trials. 4, 4, 9 p., 1000178.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population

    Li, S., Besenbacher, S., Li, Y., Kristiansen, Karsten, Grarup, Niels, Albrechtsen, Anders, Sparsø, T. H., Korneliussen, Thorfinn Sand, Hansen, Torben, Wang, J., Nielsen, Rasmus, Pedersen, Oluf Borbye, Bolund, L. & Schierup, M. H., 2014, In: European Journal of Human Genetics. 22, p. 1040-1045 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification

    Husemoen, L. L. N., Skaaby, T., Jørgensen, T., Thuesen, B. H., Fenger, M., Grarup, Niels, Sandholt, C. H., Hansen, Torben, Pedersen, Oluf Borbye & Linneberg, Allan René, 24 Jan 2014, In: European Journal of Nutrition. 53, 7, p. 1549-59 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes

    Steinthorsdottir, V., Thorleifsson, G., Sulem, P., Helgason, H., Grarup, N., Sigurdsson, A., Helgadottir, H. T., Johannsdottir, H., Magnusson, O. T., Gudjonsson, S. A., Justesen, J. M., Harder, M. N., Jørgensen, M. E., Christensen, C., Brandslund, I., Sandbæk, A., Lauritzen, T., Vestergaard, H., Linneberg, A., Jørgensen, T. & 14 others, Hansen, Torben, Daneshpour, M. S., Fallah, M., Hreidarsson, A. B., Sigurdsson, G., Azizi, F., Benediktsson, R., Masson, G., Helgason, A., Kong, A., Gudbjartsson, D. F., Pedersen, Oluf Borbye, Thorsteinsdottir, U. & Stefansson, K., 26 Jan 2014, In: Nature Genetics. 46, 3, p. 294-300 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients with Maturity Onset Diabetes of the Young - Type 2 and Type 3

    Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 27 Mar 2014, In: Diabetes. 63, 8, p. 2838-44 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    A functional amino acid substitution in the glucose-dependent insulinotropic polypeptide receptor (GIPR) gene is associated with lower bone mineral density and increased fracture risk

    Torekov, Signe Sørensen, Harsløf, T., Rejnmark, L., Eiken, P., Jensen, Jens-Erik Beck, Herman, A. P., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul & Langdahl, B. L., Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 4, p. E729-33 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Interaction between genetic predisposition to obesity and dietary calcium in relation to subsequent change in body weight and waist circumference

    Larsen, S. C., Ängquist, Lars, Ahluwalia, Tarun Veer Singh, Skaaby, T., Roswall, N., Tjønneland, A., Halkjær, J., Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Heitmann, Berit & Sørensen, Thorkild I.A., Apr 2014, In: The American Journal of Clinical Nutrition. 99, 4

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    KCNQ1 Long QT syndrome patients have hyperinsulinemia and symptomatic hypoglycemia

    Torekov, Signe Sørensen, Iepsen, E., Christiansen, M., Linneberg, Allan René, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K. & Hansen, Torben, Apr 2014, In: Diabetes. 63, 4, p. 1315-1325 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

    Flannick, J., Thorleifsson, G., Beer, N. L., Jacobs, S. B. R., Grarup, N., Burtt, N. P., Mahajan, A., Fuchsberger, C., Atzmon, G., Benediktsson, R., Blangero, J., Bowden, D. W., Brandslund, I., Brosnan, J., Burslem, F., Chambers, J., Cho, Y. S., Christensen, C., Douglas, D. A., Duggirala, R. & 31 others, Dymek, Z., Farjoun, Y., Fennell, T., Fontanillas, P., Forsén, T., Gabriel, S., Glaser, B., Gudbjartsson, D. F., Hanis, C., Hansen, Torben, Hreidarsson, A. B., Hveem, K., Ingelsson, E., Isomaa, B., Johansson, S., Jørgensen, T., Jørgensen, M. E., Kathiresan, S., Kong, A., Kooner, J., Kravic, J., Laakso, M., Lee, J., Lind, L., Lindgren, C. M., Linneberg, Allan René, Masson, G., Meitinger, T., Ribel-Madsen, R., Pedersen, Oluf Borbye & Go-T2D Consortium, G. C., Apr 2014, In: Nature Genetics. 46, 4, p. 357-63 7 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  20. Published

    High heritability and genetic correlation of intravenous glucose- and tolbutamide-induced insulin secretion among non-diabetic family members of type 2 diabetic patients

    Gjesing, A. M. P., Hornbak, M., Allin, K. H., Ekstrøm, Claus Thorn, Urhammer, Søren Asger, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye & Hansen, Torben, Jun 2014, In: Diabetologia. 57, 6, p. 1173-1181 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Lessons from whole-exome sequencing in MODYX families

    Dusatkova, P., Fang, M., Pruhova, S., Gjesing, A. P., Cinek, O., Hansen, Torben, Pedersen, Oluf Borbye, Xu, X. & Lebl, J., Jun 2014, In: Diabetes Research and Clinical Practice. 104, 3, p. e72-4 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial

    Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Faber, Jens, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 14 Jun 2014, In: Diabetes Care. 37, 7, p. 1797-1805 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond

    Grarup, Niels, Sandholt, C. H., Hansen, Torben & Pedersen, Oluf Borbye, Aug 2014, In: Diabetologia. 57, 8, p. 1528-41 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility

    Guigas, B., de Leeuw van Weenen, J. E., van Leeuwen, N., Simonis-Bik, A. M., van Haeften, T. W., Nijpels, G., Houwing-Duistermaat, J. J., Beekman, M., Deelen, J., Havekes, L. M., Penninx, B. W. J. H., Vogelzangs, N., van 't Riet, E., Dehghan, A., Hofman, A., Witteman, J. C., Uitterlinden, A. G., Grarup, N., Jørgensen, T., Witte, D. R. & 15 others, Lauritzen, T., Hansen, Torben, Pedersen, Oluf Borbye, Hottenga, J., Romijn, J. A., Diamant, M., Kramer, M. H. H., Heine, R. J., Willemsen, G., Dekker, J. M., Eekhoff, E. M., Pijl, H., de Geus, E. J., Slagboom, P. E. & 't Hart, L. M., Aug 2014, In: Diabetic Medicine. 31, 8, p. 1001-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals

    Qi, Q., Oskari Kilpeläinen, T., Downer, M. K., Tanaka, T., Smith, C. E., Sluijs, I., Sonestedt, E., Chu, A. Y., Renström, F., Lin, X., Angquist, L. H., Huang, J., Liu, Z., Li, Y., Asif Ali, M., Xu, M., Ahluwalia, T. V. S., Boer, J. M. A., Chen, P., Daimon, M. & 89 others, Eriksson, J., Perola, M., Friedlander, Y., Gao, Y., Heppe, D. H. M., Holloway, J. W., Houston, D. K., Kanoni, S., Kim, Y., Laaksonen, M. A., Jääskeläinen, T., Lee, N. R., Lehtimäki, T., Lemaitre, R. N., Lu, W., Luben, R. N., Manichaikul, A., Männistö, S., Marques-Vidal, P., Monda, K. L., Ngwa, J. S., Perusse, L., van Rooij, F. J. A., Xiang, Y., Wen, W., Wojczynski, M. K., Zhu, J., Borecki, I. B., Bouchard, C., Cai, Q., Cooper, C., Dedoussis, G. V., Deloukas, P., Ferrucci, L., Forouhi, N. G., Hansen, Torben, Christiansen, L., Hofman, A., Johansson, I., Jørgensen, T., Karasawa, S., Khaw, K., Kim, M., Kristiansson, K., Li, H., Lin, X., Liu, Y., Lohman, K. K., Long, J., Mikkilä, V., Mozaffarian, D., North, K., Pedersen, Oluf Borbye, Raitakari, O., Rissanen, H., Tuomilehto, J., van der Schouw, Y. T., Uitterlinden, A. G., Carola Zillikens, M., Franco, O. H., Shyong Tai, E., Ou Shu, X., Siscovick, D. S., Toft, Ulla Marie Nørgaard, Monique Verschuren, W. M., Vollenweider, P., Wareham, N. J., Witteman, J. C. M., Zheng, W., Ridker, P. M., Kang, J. H., Liang, L., Jensen, M. K., Curhan, G. C., Pasquale, L. R., Hunter, D. J., Mohlke, K. L., Uusitupa, M., Adrienne Cupples, L., Rankinen, T., Orho-Melander, M., Wang, T., Chasman, D. I., Franks, P. W., Sørensen, Thorkild I.A., Hu, F. B., Loos, R. J. F., Nettleton, J. A. & Qi, L., 7 Aug 2014, In: Human Molecular Genetics. 23, 25, p. 6961-6972 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Tarmbakterier kan have betydning for overvægt i barnealderen

    Fonvig, C. E., Pihl, A. F., Hansen, Torben, Pedersen, Oluf Borbye & Holm, Jens-Christian, 18 Aug 2014, In: Ugeskrift for Laeger. 176, p. 2-6 5 p., V03140171.

    Research output: Contribution to journal › Journal article › Research › peer-review

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